Włókniaki
Epidemiologia
Enterobius vermicularis, powszechnie znany jako włókniak lub owsik, jest najczęstszą helmintozą na świecie, szczególnie w klimacie umiarkowanym, z szacowaną globalną częstością zakażeń około 1 miliarda przypadków. W populacjach dziecięcych częstość występowania waha się od 0,2% do 61% w zależności od regionu, z najwyższą zapadalnością u dzieci w wieku 5-9 lat. W USA zakażonych jest około 40 milionów osób, a w instytucjach zamkniętych częstość może sięgać nawet 50-100%. Zakażenie przenosi się głównie drogą fekalno-oralną, a jaja pasożyta mogą przetrwać na powierzchniach do 2 tygodni, co sprzyja reinfekcjom. Diagnostyka wymaga wielokrotnych badań próbek kału ze względu na przerywany charakter wydalania jaj. Brak nabytej odporności powoduje, że ponowne zakażenia są częste, co utrudnia eradykację.
Epidemiologia włókniaków
Włókniaki (threadworms), znane również jako owsiki (Enterobius vermicularis), są najczęstszą inwazją helmintyczną na świecie, szczególnie w regionach o umiarkowanym klimacie. Zakażenie to charakteryzuje się szerokim rozpowszechnieniem geograficznym, dotykając wszystkie grupy społeczno-ekonomiczne niezależnie od rasy czy pochodzenia kulturowego.12 Stanowi wyjątek od zasady, że pasożyty jelitowe są rzadko spotykane w zamożnych społecznościach.3
Rozpowszechnienie na świecie
Szacuje się, że około 1 miliarda ludzi na całym świecie jest zarażonych włókniakami.45 W Stanach Zjednoczonych liczba zakażonych osób szacowana jest na około 40 milionów.67 Częstość występowania włókniaków w populacji ogólnej wynosi około 5-15%, jednak w ostatnich latach zaobserwowano jej spadek.89
Badania częstości występowania u dzieci w różnych krajach europejskich wykazały zróżnicowane wyniki:1011
Badanie norweskie wykazało, że 18% z 395 przebadanych dzieci miało pozytywny wynik testu na obecność jaj Enterobius, z najwyższą częstością występowania (34%) wśród dzieci w wieku 6-11 lat.17 Natomiast w badaniu z Niemiec przeprowadzonym w obszarze Berlina zaobserwowano, że odsetek dodatnich wyników podwoił się w latach 2007-2017 (z 12,7% do 23,6%), z sezonowym szczytem między październikiem a grudniem.18
Grupy wysokiego ryzyka
Włókniaki dotykają przede wszystkim dzieci, szczególnie w wieku szkolnym. Ogólna częstość występowania u dzieci wynosi od 0,2% do 20% w Stanach Zjednoczonych.19 Badania przeprowadzone wśród dzieci bez objawów sugerują, że między 18% a 34% dzieci ma włókniaki.20
Najwyższą częstość występowania obserwuje się u dzieci w wieku 5-9 lat.2122 U dorosłych zakażenie jest najczęstsze wśród rodziców w wieku 30-39 lat, zwykle z powodu przeniesienia od ich dzieci.2324
Istotne jest również występowanie zakażeń w ośrodkach opiekuńczych oraz instytucjach zamkniętych, gdzie częstość może osiągać nawet 50-100%.2526
Ogólnie, mężczyźni są dotknięci dwukrotnie częściej niż kobiety, z wyjątkiem osób w wieku 5-14 lat, gdy zakażenie dominuje u dziewczynek.2728
Czynniki ryzyka
Do głównych czynników ryzyka zakażenia włókniakami należą:293031
- Mieszkanie z osobą zakażoną
- Jedzenie przed umyciem rąk
- Słaba higiena osobista lub grupowa
- Przebywanie w placówkach o dużym zagęszczeniu (przedszkola, szkoły, instytucje zamknięte)
- Nawyki takie jak ssanie kciuka czy obgryzanie paznokci
- Większa liczebność rodziny
Mechanizmy transmisji i przetrwania pasożyta
Włókniaki rozprzestrzeniają się poprzez połknięcie jaj pasożyta. Samice składają jaja wokół odbytu, co powoduje świąd. Podczas drapania jaja przyczepiają się do palców, a następnie mogą być przenoszone na różne powierzchnie, w tym żywność, ubrania, pościel i meble.3233
Jaja mogą przetrwać na powierzchniach do 2 tygodni.3435 Po połknięciu larwy wylęgają się w jelitach i dojrzewają do postaci dorosłych w ciągu 1-2 miesięcy.36
Przenoszenie zakażenia następuje głównie drogą fekalno-oralną, ale może również nastąpić przez wdychanie jaj unoszących się w powietrzu, które następnie są połykane.3738
Istnieją trzy mechanizmy zapewniające przetrwanie pasożyta:39
- Zdolność przetrwania przez pewien czas w formie niepasożytniczej
- Możliwe różne drogi transmisji
- Zdolność do osiągnięcia dojrzałości w ciągu kilku dni
Obserwowane trendy w zakażeniach włókniakami
W regionach o wysokim poziomie zasobów, takich jak Tajwan, zaobserwowano stopniowy spadek częstości występowania zakażeń włókniakami wśród dzieci w wieku szkolnym w latach 2009-2018. Jednakże, co istotne, nie stwierdzono tendencji spadkowej w obszarach wiejskich, gdzie zakażenie włókniakami pozostaje istotnym problemem zdrowia publicznego.40
Badanie przeprowadzone w ośrodku rozwojowym wykazało, że częstość występowania enterbiozy spadła szybko i stopniowo z 21% przed wprowadzeniem masowych leków do 1% po 3 latach.41
Mimo to, całkowita eradykacja pasożyta okazała się trudna do osiągnięcia. Nawet po masowym leczeniu, zakażenie włókniakami nie zostało całkowicie wyeliminowane.42
Wyzwania w nadzorze i kontroli
Istnieją przesłanki sugerujące, że zakażenia włókniakami są niedodiagnozowane i niedostatecznie zgłaszane w niektórych regionach, takich jak Stany Zjednoczone.43 Prawdziwy zakres i obciążenie chorobą nie są dobrze zrozumiane.44
Skuteczny nadzór wymaga testowania próbek kału w wielu punktach czasowych lub od wielu osób w jednym punkcie czasowym, ponieważ jaja pasożyta są wydalane z kałem zakażonych zwierząt w sposób przerywany.45
Warto zauważyć, że zakażeniu nie towarzyszy nabycie odporności, co oznacza, że ponowne zakażenie jest możliwe.46
Strategie kontroli i zapobiegania
Skuteczna kontrola zakażeń włókniakami wymaga kompleksowego podejścia obejmującego zarówno leczenie farmakologiczne, jak i środki higieniczne.4748
Leczenie grupowe
Dla skutecznej kontroli enterbiozy, wszystkie osoby z gospodarstwa domowego powinny być leczone dwoma dawkami leku przeciwrobaczego, w odstępie 14 dni.4950 Jest to konieczne, ponieważ jeśli jeden członek gospodarstwa domowego jest zakażony, często inni również są zakażeni.51
Zakażenia leczy się najczęściej iwermektyną, choć niektóre nicienie zaczynają rozwijać oporność na ten lek pierwszego rzutu.52
Środki higieniczne
Aby zapobiec reinfekcji, należy podkreślić znaczenie ogólnych środków kontroli:5354
- Dokładne mycie rąk, szczególnie po korzystaniu z toalety i przed jedzeniem
- Przycinanie paznokci
- Codzienne mycie okolic krocza
- Kontrola pica (spożywania substancji niejadalnych)
- Utrzymanie czystości w domu
- Stosowanie długich piżam zamiast koszul nocnych
Jaja włókniaków mogą przetrwać do 2 tygodni poza ciałem na bieliźnie, pościeli i innych przedmiotach. Dobre środki higieniczne pomogą usunąć jaja z ciała i domu, a tym samym zapobiec ponownej infekcji.55
Nadzór i kontrola w społecznościach
W społecznościach endemicznych możliwe są obecnie strategie kontroli dzięki udoskonalonym testom diagnostycznym i skutecznym schematom leczenia. Niektóre placówki zdrowotne w takich społecznościach włączyły serologię włókniaków do dwuletnich kontroli zdrowia dorosłych, aby zapewnić lepsze leczenie pacjentów z przewlekłymi zakażeniami.56
Eradykacja włókniaków z instytucji jest bardzo trudna i wymaga długoterminowego nadzoru.57 W przypadku ognisk zakażeń w ośrodkach badawczych stosuje się rygorystyczne protokoły nadzoru i monitorowania patogenów w celu zapobiegania rozprzestrzenianiu się infekcji.58
Konsekwencje zdrowotne i znaczenie dla zdrowia publicznego
Mimo że zakażenie włókniakami jest powszechne, zazwyczaj nie powoduje poważnych problemów zdrowotnych.59 Jednak ze względu na łatwość przenoszenia i wysoką częstość występowania, stanowi istotne wyzwanie dla zdrowia publicznego, szczególnie wśród dzieci i w środowiskach instytucjonalnych.
W wielu regionach o wysokim poziomie zasobów zakażenie włókniakami pozostaje ważnym problemem zdrowia publicznego, pomimo malejącej częstości występowania.60 Tym bardziej istotne jest więc zwiększanie świadomości na temat tej choroby zarówno wśród społeczności, jak i pracowników ochrony zdrowia.61
Zakażenie włókniakami jest około 3 razy częstsze niż wszawica głowy wśród małych dzieci w Stanach Zjednoczonych.62 Ta statystyka podkreśla znaczenie tej inwazji pasożytniczej w kontekście zdrowia publicznego.
Znaczenie edukacji zdrowotnej
Edukacja zdrowotna dotycząca znaczenia mycia rąk może pomóc w zapobieganiu rozprzestrzeniania się włókniaków.63 Szczególnie ważne jest zachęcanie dzieci do regularnego mycia rąk, ponieważ mogą one zarazić się włókniakami ponownie po leczeniu, jeśli jaja dostaną się do ich ust.64
Szeroko zakrojone programy edukacyjne skupiające się na higienie mogą przyczynić się do zmniejszenia częstości występowania zakażeń włókniakami i poprawy ogólnego stanu zdrowia publicznego, szczególnie w społecznościach o wysokim ryzyku.
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Materiały źródłowe
- #1 Pinworm (threadworm) infectionhttps://www.health.vic.gov.au/infectious-diseases/pinworm-threadworm-infection
The pinworm is the most common helminth parasite of temperate regions. These infections are found worldwide and affect all socioeconomic groups. […] The pinworm is the most common helminth parasite of temperate regions. These infections are found worldwide and affect all socioeconomic groups. […] Pinworm infections predominantly affect paediatric populations, in which the prevalence is reported to be 1050 per cent in some groups. […] Pinworms are transmitted by direct transfer of infected eggs by hand from the anus to the mouth of the same or another person. They can also be transmitted indirectly through bedding, clothing, food or other articles. Spread is facilitated by overcrowding. […] Communicability continues as long as the eggs are being discharged onto the perianal area. The eggs can survive for several days in the right conditions. Reinfection from contaminated hands is common. […] Infection does not confer immunity. […] Public health education on the importance of handwashing may assist. […] Infectious diseases surveillance in Victoria.
- #2 Pinworm (parasite) – Wikipediahttps://en.wikipedia.org/wiki/Pinworm_(parasite)
The pinworm has a worldwide distribution, and is the cause of the most common helminthiasis (parasitic worm infection) in the United States, western Europe, and Oceania. […] In the United States, a study by the Center of Disease Control reported an overall incidence rate of 11.4% among children. […] Pinworms are particularly common in children, with prevalence rates in this age group having been reported as high as 61% in India, 50% in England, 39% in Thailand, 37% in Sweden, and 29% in Denmark. […] Because it spreads from host to host through contamination, pinworms are common among people living in close contact, and tends to occur in all people within a household. […] The prevalence of pinworms is not associated with gender, nor with any particular social class, race, or culture. […] Pinworms are an exception to the tenet that intestinal parasites are uncommon in affluent communities.
- #3 Pinworm infection – Wikipediahttps://en.wikipedia.org/wiki/Pinworm_infection
Pinworm infection occurs worldwide, and is the most common helminth (i.e., parasitic worm) infection in the United States and Western Europe. In the United States, a study by the Center of Disease Control reported an overall incidence rate of 11.4% among people of all ages. Pinworms are particularly common in children with approximately 30% of children being infected and most commonly seen in children between 7 and 11 years old. The prevalence rates in children having been reported as high as 61% in India, 50% in England, 39% in Thailand, 37% in Sweden, and 29% in Denmark. […] Because it spreads from host to host through contamination, enterobiasis is common among people living in close contact, and tends to occur in all people within a household. The prevalence of pinworms is not associated with gender, nor with any particular social class, race, or culture. Pinworms are an exception to the tenet that intestinal parasites are uncommon in affluent communities.
- #4 Pinworms (Threadworms): Symptoms, How You Get Them & Treatmenthttps://my.clevelandclinic.org/health/diseases/21137-pinworms
Enterobiasis is the most common type of worm infection in the United States. It affects approximately 40 million people in the U.S. and 1 billion people worldwide. […] Pinworm infections pass easily from person to person in places where children are in close contact, including daycare centers, preschools and schools. People who live in institutions also commonly get infected. […] Theyre highly contagious. Transmission is easy because the eggs can survive for a long time on surfaces or your fingers if you dont wash your hands. […] The most effective way to prevent a pinworm infection (or reinfection) is by preventing the eggs from reaching your childs (or your) mouth.
- #5 The Diagnosis and Treatment of Pinworm Infection (29.03.2019)https://di.aerzteblatt.de/int/archive/article/206305/The-diagnosis-and-treatment-of-pinworm-infection
Rough estimates put the worldwide E. vermicularis infection rate at more than a billion people. […] Pinworm infection is also common in moderate climates and industrial countries, where it is seen at all social levels. […] Frequency analyses in children have been conducted for some European countries: a Norwegian study found that 18% of 395 children tested positive for Enterobius eggs using the Scotch tape test, with the highest prevalence (34%) among 6- to 11-year-olds. […] A recent German study conducted in the greater Berlin area showed that the rate of positive detections doubled during the period 2007-2017 (from 12.7% to 23.6%), with a seasonal peak between October and December. […] Despite a high disease incidence, there is surprisingly scant systematically proven knowledge on treatment not to mention a German-language guideline; therefore, since general practitioners, as well as infectious disease and pediatric outpatient departments, are nevertheless regularly confronted with enterobiasis, this article aims to summarize the current state of knowledge in order to ensure optimal diagnosis and treatment.
- #6 Enterobius Vermicularis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK536974/
Enterobius vermicularis, also called pinworm, is one of the most common helminth infections in the world, with most cases occurring in children. […] Describe the epidemiology of Enterobius vermicularis infection. […] The male to female infection frequency is 2 to 1. However, a female predominance of infection is seen in those between the ages of 5 and 14 years. It most commonly affects children younger than 18 years of age. It is also commonly seen in adults who take care of children and institutionalized children. Center for Disease Control and Prevention data indicates that there are about 40 million people estimated to have been infected in the United States. Transmission can occur via contact with contaminated clothes, bedding, personal care products, and furniture. Fecal-oral is the most common mode of transmission. Rarely, transmission can occur via inhalation mode when eggs are inhaled and then subsequently swallowed. […] Eradicating pinworms from institutions is very difficult and long term surveillance is required.
- #7 Enterobius (Pinworm) | Johns Hopkins ABX Guidehttps://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540202/all/Enterobius__Pinworm_?q=E+Hepatitis
Epidemiology: worldwide, with 40 million cases per year. Infection is mostly seen in children. […] Most common nematode infection in the U.S. […] Increased prevalence with congestion, institutionalization, and poor sanitation. […] A larger family size is associated with increased risk.
- #8 Enterobiasis (Pinworm Infestation): Practice Essentials, Pathophysiology, Epidemiologyhttps://emedicine.medscape.com/article/997814-overview
Prevalence is approximately 5-15% in the general population; however, this rate has declined in recent years. Prevalence rates are probably higher in institutionalized individuals. Humans are the only known host. […] Infestation rate increases with increased population density, and with personal habits such as thumb sucking and nail biting. […] E vermicularis infestation occurs worldwide. Prevalence data vary by country. […] A study that aimed to determine the extent of enterobiasis, strongyloidiasis, and other helminth infections in infants, preschool-aged, and school-aged children from rural coastal Tanzania reported that E vermicularis infestations were found in 4.2% of infants, 16.7%, of preschool-aged children, and 26.3% of school-aged children. […] A study of kindergarten students in the Republic of the Marshall Islands found that the overall prevalence of E vermicularis infestation was 22.4%. The prevalence was higher among boys (24.5%) than among girls (20.31%) in the study.
- #9 Enterobius/Enterobiasis | Concise Medical Knowledgehttps://www.lecturio.com/concepts/enterobius-enterobiasis/
Enterobiasis is the most common helminth infection in the United States and Western Europe. […] Prevalence in the United States: 5%-15% of the general population (approximately 40 million people). […] Worldwide: 60 million to 100 million infections annually. […] Prevalence in primary school children: 34.7%. […] 13% of children around the world have been infected with E. vermicularis.
- #10 Pinworm (parasite) – Wikipediahttps://en.wikipedia.org/wiki/Pinworm_(parasite)
The pinworm has a worldwide distribution, and is the cause of the most common helminthiasis (parasitic worm infection) in the United States, western Europe, and Oceania. […] In the United States, a study by the Center of Disease Control reported an overall incidence rate of 11.4% among children. […] Pinworms are particularly common in children, with prevalence rates in this age group having been reported as high as 61% in India, 50% in England, 39% in Thailand, 37% in Sweden, and 29% in Denmark. […] Because it spreads from host to host through contamination, pinworms are common among people living in close contact, and tends to occur in all people within a household. […] The prevalence of pinworms is not associated with gender, nor with any particular social class, race, or culture. […] Pinworms are an exception to the tenet that intestinal parasites are uncommon in affluent communities.
- #11 Pinworm infection – Wikipediahttps://en.wikipedia.org/wiki/Pinworm_infection
Pinworm infection occurs worldwide, and is the most common helminth (i.e., parasitic worm) infection in the United States and Western Europe. In the United States, a study by the Center of Disease Control reported an overall incidence rate of 11.4% among people of all ages. Pinworms are particularly common in children with approximately 30% of children being infected and most commonly seen in children between 7 and 11 years old. The prevalence rates in children having been reported as high as 61% in India, 50% in England, 39% in Thailand, 37% in Sweden, and 29% in Denmark. […] Because it spreads from host to host through contamination, enterobiasis is common among people living in close contact, and tends to occur in all people within a household. The prevalence of pinworms is not associated with gender, nor with any particular social class, race, or culture. Pinworms are an exception to the tenet that intestinal parasites are uncommon in affluent communities.
- #12 Pinworm (parasite) – Wikipediahttps://en.wikipedia.org/wiki/Pinworm_(parasite)
The pinworm has a worldwide distribution, and is the cause of the most common helminthiasis (parasitic worm infection) in the United States, western Europe, and Oceania. […] In the United States, a study by the Center of Disease Control reported an overall incidence rate of 11.4% among children. […] Pinworms are particularly common in children, with prevalence rates in this age group having been reported as high as 61% in India, 50% in England, 39% in Thailand, 37% in Sweden, and 29% in Denmark. […] Because it spreads from host to host through contamination, pinworms are common among people living in close contact, and tends to occur in all people within a household. […] The prevalence of pinworms is not associated with gender, nor with any particular social class, race, or culture. […] Pinworms are an exception to the tenet that intestinal parasites are uncommon in affluent communities.
- #13 Pinworm (parasite) – Wikipediahttps://en.wikipedia.org/wiki/Pinworm_(parasite)
The pinworm has a worldwide distribution, and is the cause of the most common helminthiasis (parasitic worm infection) in the United States, western Europe, and Oceania. […] In the United States, a study by the Center of Disease Control reported an overall incidence rate of 11.4% among children. […] Pinworms are particularly common in children, with prevalence rates in this age group having been reported as high as 61% in India, 50% in England, 39% in Thailand, 37% in Sweden, and 29% in Denmark. […] Because it spreads from host to host through contamination, pinworms are common among people living in close contact, and tends to occur in all people within a household. […] The prevalence of pinworms is not associated with gender, nor with any particular social class, race, or culture. […] Pinworms are an exception to the tenet that intestinal parasites are uncommon in affluent communities.
- #14 Pinworm (parasite) – Wikipediahttps://en.wikipedia.org/wiki/Pinworm_(parasite)
The pinworm has a worldwide distribution, and is the cause of the most common helminthiasis (parasitic worm infection) in the United States, western Europe, and Oceania. […] In the United States, a study by the Center of Disease Control reported an overall incidence rate of 11.4% among children. […] Pinworms are particularly common in children, with prevalence rates in this age group having been reported as high as 61% in India, 50% in England, 39% in Thailand, 37% in Sweden, and 29% in Denmark. […] Because it spreads from host to host through contamination, pinworms are common among people living in close contact, and tends to occur in all people within a household. […] The prevalence of pinworms is not associated with gender, nor with any particular social class, race, or culture. […] Pinworms are an exception to the tenet that intestinal parasites are uncommon in affluent communities.
- #15 Pinworm (parasite) – Wikipediahttps://en.wikipedia.org/wiki/Pinworm_(parasite)
The pinworm has a worldwide distribution, and is the cause of the most common helminthiasis (parasitic worm infection) in the United States, western Europe, and Oceania. […] In the United States, a study by the Center of Disease Control reported an overall incidence rate of 11.4% among children. […] Pinworms are particularly common in children, with prevalence rates in this age group having been reported as high as 61% in India, 50% in England, 39% in Thailand, 37% in Sweden, and 29% in Denmark. […] Because it spreads from host to host through contamination, pinworms are common among people living in close contact, and tends to occur in all people within a household. […] The prevalence of pinworms is not associated with gender, nor with any particular social class, race, or culture. […] Pinworms are an exception to the tenet that intestinal parasites are uncommon in affluent communities.
- #16 Pinworm (parasite) – Wikipediahttps://en.wikipedia.org/wiki/Pinworm_(parasite)
The pinworm has a worldwide distribution, and is the cause of the most common helminthiasis (parasitic worm infection) in the United States, western Europe, and Oceania. […] In the United States, a study by the Center of Disease Control reported an overall incidence rate of 11.4% among children. […] Pinworms are particularly common in children, with prevalence rates in this age group having been reported as high as 61% in India, 50% in England, 39% in Thailand, 37% in Sweden, and 29% in Denmark. […] Because it spreads from host to host through contamination, pinworms are common among people living in close contact, and tends to occur in all people within a household. […] The prevalence of pinworms is not associated with gender, nor with any particular social class, race, or culture. […] Pinworms are an exception to the tenet that intestinal parasites are uncommon in affluent communities.
- #17 The Diagnosis and Treatment of Pinworm Infection (29.03.2019)https://di.aerzteblatt.de/int/archive/article/206305/The-diagnosis-and-treatment-of-pinworm-infection
Rough estimates put the worldwide E. vermicularis infection rate at more than a billion people. […] Pinworm infection is also common in moderate climates and industrial countries, where it is seen at all social levels. […] Frequency analyses in children have been conducted for some European countries: a Norwegian study found that 18% of 395 children tested positive for Enterobius eggs using the Scotch tape test, with the highest prevalence (34%) among 6- to 11-year-olds. […] A recent German study conducted in the greater Berlin area showed that the rate of positive detections doubled during the period 2007-2017 (from 12.7% to 23.6%), with a seasonal peak between October and December. […] Despite a high disease incidence, there is surprisingly scant systematically proven knowledge on treatment not to mention a German-language guideline; therefore, since general practitioners, as well as infectious disease and pediatric outpatient departments, are nevertheless regularly confronted with enterobiasis, this article aims to summarize the current state of knowledge in order to ensure optimal diagnosis and treatment.
- #18 The Diagnosis and Treatment of Pinworm Infection (29.03.2019)https://di.aerzteblatt.de/int/archive/article/206305/The-diagnosis-and-treatment-of-pinworm-infection
Rough estimates put the worldwide E. vermicularis infection rate at more than a billion people. […] Pinworm infection is also common in moderate climates and industrial countries, where it is seen at all social levels. […] Frequency analyses in children have been conducted for some European countries: a Norwegian study found that 18% of 395 children tested positive for Enterobius eggs using the Scotch tape test, with the highest prevalence (34%) among 6- to 11-year-olds. […] A recent German study conducted in the greater Berlin area showed that the rate of positive detections doubled during the period 2007-2017 (from 12.7% to 23.6%), with a seasonal peak between October and December. […] Despite a high disease incidence, there is surprisingly scant systematically proven knowledge on treatment not to mention a German-language guideline; therefore, since general practitioners, as well as infectious disease and pediatric outpatient departments, are nevertheless regularly confronted with enterobiasis, this article aims to summarize the current state of knowledge in order to ensure optimal diagnosis and treatment.
- #19 Pinworm (Enterobiasis): Practice Essentials, Etiology, Transmissionhttps://emedicine.medscape.com/article/225652-overview
Pinworm infection, caused by the nematode Enterobius vermicularis, is prevalent in temperate regions worldwide. It primarily affects children, with transmission often occurring to parents via their children. In the US, general prevalence in children ranges from 0.2-20%, whereas in institutional settings, it can be as high as 50-100%. […] E vermicularis is the most common helminthic infestation in the United States. General prevalence in children is reported to be 0.2-20%. Pinworm infection is most common in persons who live in crowded living conditions and in individuals who are institutionalized. […] Prevalence in institutionalized persons is reported to be 50-100%. A similar prevalence of pinworm infestation has been reported in European countries. […] The general prevalence of pinworm infection in some regions may be as high as 12%. Pinworm infection is most common in cosmopolitan areas in cool and temperate regions. Egg carrier rates vary by country, from 0.1-98.4%.
- #20 Threadworms: Symptoms and Treatment | Doctorhttps://patient.info/doctor/threadworms-pro
How common are threadworms? (Epidemiology) This is the most common helminthic infection in the UK. An average GP practice of 10,000 patients would expect about 40 consultations a year for threadworms but many more simply buy medication from a pharmacist. It tends to affect family groups or institutions. […] Prevalence is highest between the ages of 5 and 9 years but all ages may be affected. Studies in asymptomatic children suggest that between 18 and 34% of children have threadworms.
- #21 Threadworms: Symptoms and Treatment | Doctorhttps://patient.info/doctor/threadworms-pro
How common are threadworms? (Epidemiology) This is the most common helminthic infection in the UK. An average GP practice of 10,000 patients would expect about 40 consultations a year for threadworms but many more simply buy medication from a pharmacist. It tends to affect family groups or institutions. […] Prevalence is highest between the ages of 5 and 9 years but all ages may be affected. Studies in asymptomatic children suggest that between 18 and 34% of children have threadworms.
- #22 Pinworm (Enterobiasis): Practice Essentials, Etiology, Transmissionhttps://emedicine.medscape.com/article/225652-overview
Of all age groups, school-aged children are most at risk for pinworm infections. In adults, pinworm infection is most common in parents aged 30-39 years, typically owing to transmission from their children aged 5-9 years. […] Overall, males are affected twice as often as females, except in people aged 5-14 years, when infection is predominantly in females. […] Risk factors for pinworms include living with a person who is egg-positive, eating before washing hands, and poor personal or group hygiene.
- #23 Pinworm (Enterobiasis): Practice Essentials, Etiology, Transmissionhttps://emedicine.medscape.com/article/225652-overview
Of all age groups, school-aged children are most at risk for pinworm infections. In adults, pinworm infection is most common in parents aged 30-39 years, typically owing to transmission from their children aged 5-9 years. […] Overall, males are affected twice as often as females, except in people aged 5-14 years, when infection is predominantly in females. […] Risk factors for pinworms include living with a person who is egg-positive, eating before washing hands, and poor personal or group hygiene.
- #24 Pinworm: A Common Human Parasitehttps://www.uspharmacist.com/article/pinworm-a-common-human-parasite
Pinworm infestation is linked to age, being most common in children of school age, followed by preschool children. […] Adults are the least common age-group to experience enterobiasis, with the exception of mothers whose children are infested. […] Children attending day care and other institutions are at greater risk for pinworm because of the high potential for transmission to those who are closely associated with the first case in the household. […] While some authors assert that pinworm crosses all social barriers, others state that poverty and poor personal hygiene increase the risk of infestation.
- #25 Pinworm (Enterobiasis): Practice Essentials, Etiology, Transmissionhttps://emedicine.medscape.com/article/225652-overview
Pinworm infection, caused by the nematode Enterobius vermicularis, is prevalent in temperate regions worldwide. It primarily affects children, with transmission often occurring to parents via their children. In the US, general prevalence in children ranges from 0.2-20%, whereas in institutional settings, it can be as high as 50-100%. […] E vermicularis is the most common helminthic infestation in the United States. General prevalence in children is reported to be 0.2-20%. Pinworm infection is most common in persons who live in crowded living conditions and in individuals who are institutionalized. […] Prevalence in institutionalized persons is reported to be 50-100%. A similar prevalence of pinworm infestation has been reported in European countries. […] The general prevalence of pinworm infection in some regions may be as high as 12%. Pinworm infection is most common in cosmopolitan areas in cool and temperate regions. Egg carrier rates vary by country, from 0.1-98.4%.
- #26 Enterobiasis (Pinworm Infestation): Practice Essentials, Pathophysiology, Epidemiologyhttps://emedicine.medscape.com/article/997814-overview
Prevalence is approximately 5-15% in the general population; however, this rate has declined in recent years. Prevalence rates are probably higher in institutionalized individuals. Humans are the only known host. […] Infestation rate increases with increased population density, and with personal habits such as thumb sucking and nail biting. […] E vermicularis infestation occurs worldwide. Prevalence data vary by country. […] A study that aimed to determine the extent of enterobiasis, strongyloidiasis, and other helminth infections in infants, preschool-aged, and school-aged children from rural coastal Tanzania reported that E vermicularis infestations were found in 4.2% of infants, 16.7%, of preschool-aged children, and 26.3% of school-aged children. […] A study of kindergarten students in the Republic of the Marshall Islands found that the overall prevalence of E vermicularis infestation was 22.4%. The prevalence was higher among boys (24.5%) than among girls (20.31%) in the study.
- #27 Enterobius Vermicularis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK536974/
Enterobius vermicularis, also called pinworm, is one of the most common helminth infections in the world, with most cases occurring in children. […] Describe the epidemiology of Enterobius vermicularis infection. […] The male to female infection frequency is 2 to 1. However, a female predominance of infection is seen in those between the ages of 5 and 14 years. It most commonly affects children younger than 18 years of age. It is also commonly seen in adults who take care of children and institutionalized children. Center for Disease Control and Prevention data indicates that there are about 40 million people estimated to have been infected in the United States. Transmission can occur via contact with contaminated clothes, bedding, personal care products, and furniture. Fecal-oral is the most common mode of transmission. Rarely, transmission can occur via inhalation mode when eggs are inhaled and then subsequently swallowed. […] Eradicating pinworms from institutions is very difficult and long term surveillance is required.
- #28 Pinworm (Enterobiasis): Practice Essentials, Etiology, Transmissionhttps://emedicine.medscape.com/article/225652-overview
Of all age groups, school-aged children are most at risk for pinworm infections. In adults, pinworm infection is most common in parents aged 30-39 years, typically owing to transmission from their children aged 5-9 years. […] Overall, males are affected twice as often as females, except in people aged 5-14 years, when infection is predominantly in females. […] Risk factors for pinworms include living with a person who is egg-positive, eating before washing hands, and poor personal or group hygiene.
- #29 Pinworm (Enterobiasis): Practice Essentials, Etiology, Transmissionhttps://emedicine.medscape.com/article/225652-overview
Of all age groups, school-aged children are most at risk for pinworm infections. In adults, pinworm infection is most common in parents aged 30-39 years, typically owing to transmission from their children aged 5-9 years. […] Overall, males are affected twice as often as females, except in people aged 5-14 years, when infection is predominantly in females. […] Risk factors for pinworms include living with a person who is egg-positive, eating before washing hands, and poor personal or group hygiene.
- #30 Enterobius Vermicularis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK536974/
Enterobius vermicularis, also called pinworm, is one of the most common helminth infections in the world, with most cases occurring in children. […] Describe the epidemiology of Enterobius vermicularis infection. […] The male to female infection frequency is 2 to 1. However, a female predominance of infection is seen in those between the ages of 5 and 14 years. It most commonly affects children younger than 18 years of age. It is also commonly seen in adults who take care of children and institutionalized children. Center for Disease Control and Prevention data indicates that there are about 40 million people estimated to have been infected in the United States. Transmission can occur via contact with contaminated clothes, bedding, personal care products, and furniture. Fecal-oral is the most common mode of transmission. Rarely, transmission can occur via inhalation mode when eggs are inhaled and then subsequently swallowed. […] Eradicating pinworms from institutions is very difficult and long term surveillance is required.
- #31 Enterobiasis (Pinworm Infestation): Practice Essentials, Pathophysiology, Epidemiologyhttps://emedicine.medscape.com/article/997814-overview
Prevalence is approximately 5-15% in the general population; however, this rate has declined in recent years. Prevalence rates are probably higher in institutionalized individuals. Humans are the only known host. […] Infestation rate increases with increased population density, and with personal habits such as thumb sucking and nail biting. […] E vermicularis infestation occurs worldwide. Prevalence data vary by country. […] A study that aimed to determine the extent of enterobiasis, strongyloidiasis, and other helminth infections in infants, preschool-aged, and school-aged children from rural coastal Tanzania reported that E vermicularis infestations were found in 4.2% of infants, 16.7%, of preschool-aged children, and 26.3% of school-aged children. […] A study of kindergarten students in the Republic of the Marshall Islands found that the overall prevalence of E vermicularis infestation was 22.4%. The prevalence was higher among boys (24.5%) than among girls (20.31%) in the study.
- #32 Threadworms | NHS informhttps://www.nhsinform.scot/illnesses-and-conditions/stomach-liver-and-gastrointestinal-tract/threadworms/
Threadworm infection most commonly affects young children because they often forget to wash their hands and share toys with other children. […] People who are in close contact with someone with a threadworm infection also have a high risk of infection. This is why all members of a household need to be treated when someone has a threadworm infection. […] Threadworms spread when their eggs are swallowed. They lay eggs around your bottom (anus) or vagina, which can cause an itchy bottom. The eggs get stuck on your fingers when you scratch. They can then pass on to anything you touch, including: […] Eggs can pass to other people when they touch these surfaces and then touch their mouth. The eggs can survive up to 2 weeks. The larvae hatch from the eggs in your gut after you swallow them, and take 1 to 2 months to mature into threadworms.
- #33 Threadwormshttps://www.nhs.uk/conditions/threadworms/
Threadworms spread when their eggs are swallowed. They lay eggs around your bottom (anus), which make it itchy. The eggs get stuck on your fingers when you scratch. […] Eggs can pass to other people when they touch these surfaces and then touch their mouth. The eggs can survive up to 2 weeks. The larvae hatch from the eggs in your gut after you swallow them, and take 1 to 2 months to mature into threadworms. […] Children can get threadworms again after they’ve been treated for them if they get the eggs in their mouth. This is why it’s important to encourage children to wash their hands regularly.
- #34 Threadworms | NHS informhttps://www.nhsinform.scot/illnesses-and-conditions/stomach-liver-and-gastrointestinal-tract/threadworms/
Threadworm infection most commonly affects young children because they often forget to wash their hands and share toys with other children. […] People who are in close contact with someone with a threadworm infection also have a high risk of infection. This is why all members of a household need to be treated when someone has a threadworm infection. […] Threadworms spread when their eggs are swallowed. They lay eggs around your bottom (anus) or vagina, which can cause an itchy bottom. The eggs get stuck on your fingers when you scratch. They can then pass on to anything you touch, including: […] Eggs can pass to other people when they touch these surfaces and then touch their mouth. The eggs can survive up to 2 weeks. The larvae hatch from the eggs in your gut after you swallow them, and take 1 to 2 months to mature into threadworms.
- #35 Worms fact sheet | NHMRCNHMRCNHMRC TaglineNHMRC Taglinehttps://www.nhmrc.gov.au/about-us/publications/staying-healthy-guidelines/fact-sheets/worms
Many types of worms can infect people. In Australia, threadworm (also called pinworm) is the most common worm in children, but worms can infect people of any age. Threadworms are small, white, thread-like worms that are 2 to 13 millimetres long. The worms only infect humans, so children cannot catch threadworms from pets. […] People get threadworms by swallowing worm eggs. Worm eggs are picked up and transferred to the mouth when an infected person scratches their bottom and then touches their mouth, or when they do not wash their hands properly after going to the toilet. This keeps this infection going. The eggs can also be transferred to bedding, clothes and other surfaces, where other people can pick them up. Eggs can survive on surfaces for up to 2 weeks. […] Not excluded – people with worms can attend the service.
- #36 Threadwormshttps://www.nhs.uk/conditions/threadworms/
Threadworms spread when their eggs are swallowed. They lay eggs around your bottom (anus), which make it itchy. The eggs get stuck on your fingers when you scratch. […] Eggs can pass to other people when they touch these surfaces and then touch their mouth. The eggs can survive up to 2 weeks. The larvae hatch from the eggs in your gut after you swallow them, and take 1 to 2 months to mature into threadworms. […] Children can get threadworms again after they’ve been treated for them if they get the eggs in their mouth. This is why it’s important to encourage children to wash their hands regularly.
- #37 Enterobius Vermicularis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK536974/
Enterobius vermicularis, also called pinworm, is one of the most common helminth infections in the world, with most cases occurring in children. […] Describe the epidemiology of Enterobius vermicularis infection. […] The male to female infection frequency is 2 to 1. However, a female predominance of infection is seen in those between the ages of 5 and 14 years. It most commonly affects children younger than 18 years of age. It is also commonly seen in adults who take care of children and institutionalized children. Center for Disease Control and Prevention data indicates that there are about 40 million people estimated to have been infected in the United States. Transmission can occur via contact with contaminated clothes, bedding, personal care products, and furniture. Fecal-oral is the most common mode of transmission. Rarely, transmission can occur via inhalation mode when eggs are inhaled and then subsequently swallowed. […] Eradicating pinworms from institutions is very difficult and long term surveillance is required.
- #38 Threadworms: Advice for Referrers | NHSGGChttps://clinicalguidelines.scot.nhs.uk/rhc-for-health-professionals/guidelines/primary-care-referral-guidelines/medical-paediatric-pre-referral-guidance/threadworms-advice-for-referrers/
Threadworm (Enterobius Vermicularis) is a parasitic infection that affects the human gut. It is the most common parasitic infection in the UK, usually affecting children under the age of 18 years. […] They are spread via the faecal-oral route when threadworm eggs are ingested. […] The eggs can survive for up to 2 weeks, so repeat infection is common. […] Any previous episodes of threadworm […] Which other members of household, if any, are displaying similar symptoms and if they have been treated. […] Threadworm eggs can survive for up to 2 weeks outside the body on underwear, bedding and other objects. Good hygiene measures will help to clear eggs from the body and home and therefore prevent re-infection. […] If re-infection occurs: Other causes of symptoms should be considered. […] However, in most cases strict hygiene measures have not been adhered to.
- #39 Threadworm Infection (Strongyloidosis) | Iowa State Universityhttps://vdl.iastate.edu/vdpam/about/focus-areas/swine/swine-disease-manual/index-diseases/threadworm-infection
Three mechanisms tend to assure survival of the parasite. These include the ability of S. ransomi to survive for some time in a non-parasitic form, four possible routes of transmission, and the ability to achieve patency in piglets in only a few days. […] Parasitic larvae invade the host either by penetration of the skin (percutaneous), ingestion in feed (oral), ingestion in colostrum (transcolostral), or through direct invasion of developing fetuses (transplacental/perinatal). […] Larvae sequestered in muscle or in the mammary fat of sows are mobilized in the periparturient period and transmitted to piglets in colostrum. This is the most common route of transmission to neonatal piglets. […] Larvae that penetrate the skin enter the blood stream and are carried to the lungs. After breaking out into alveoli and tracheal migration to the pharynx, they are swallowed and reach the small intestine.
- #40 Is pinworm infection still a public health concern among children in resource-rich regions? Trends in pinworm infection prevalence and associated factors among children in Hualien County, Taiwan: a retrospective cross-sectional study | BMC Public Health |https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-022-14641-4
Enterobius vermicularis (pinworm) is a common intestinal parasitic infection in children. A gradual decrease in the prevalence of pinworm infection has been noted in resource-rich settings, such as Taiwan. […] The overall prevalence of pinworm infection gradually decreased from 2009 to 2018 among school-age children in Hualien. However, there was no declining trend in pinworm infection in rural areas. Pinworm infection remains a major public health concern among children in rural areas of Hualien. […] However, pinworm infection is still an important public health issue in some areas of resource-rich regions, regardless of the decreasing prevalence rates. […] This study revealed the prevalence, time-trend analysis, and associated sociodemographic factors among school-age children in Hualien, Taiwan, from 2009 to 2018. […] The non-obvious decline in the trend of pinworm infection rate in the rural areas of Hualien was an important finding of this study. […] This study highlighted the fact that pinworm infection remains a vital public issue among school-age children in the rural areas of Hualien.
- #41 Epidemiology and control of enterobiasis in a developmental centerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1070873/
Enterobiasis is a common and readily transmissible helminthic infection. […] The prevalence of enterobiasis fell rapidly and progressively, from 21% before mass medication to 1% after 3 years. […] Several researchers have experimented with mass medication for enterobiasis, but their studies have been marred by high rates of reinfection, lack of a cost-benefit analysis, short follow-ups, and inadequate surveillance data. […] We describe our positive experience with mass medication, a 3-year follow-up with surveillance, and a financial analysis. […] The initiation of mass medication in 1995 progressively reduced the prevalence from 21% in 1994 to 1% in 1998. […] Our study supports the recommendation of other investigators that for the effective control of enterobiasis, all household contacts should be treated with two anthelminth doses, 14 days apart. […] Despite mass medication, enterobiasis has not been eradicated in our center. […] To prevent reinfection, general control measures (hand washing, fingernail trimming, daily perineal cleaning, pica control, housekeeping, and the use of long pajamas instead of nightgowns) should be emphasized.
- #42 Epidemiology and control of enterobiasis in a developmental centerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1070873/
Enterobiasis is a common and readily transmissible helminthic infection. […] The prevalence of enterobiasis fell rapidly and progressively, from 21% before mass medication to 1% after 3 years. […] Several researchers have experimented with mass medication for enterobiasis, but their studies have been marred by high rates of reinfection, lack of a cost-benefit analysis, short follow-ups, and inadequate surveillance data. […] We describe our positive experience with mass medication, a 3-year follow-up with surveillance, and a financial analysis. […] The initiation of mass medication in 1995 progressively reduced the prevalence from 21% in 1994 to 1% in 1998. […] Our study supports the recommendation of other investigators that for the effective control of enterobiasis, all household contacts should be treated with two anthelminth doses, 14 days apart. […] Despite mass medication, enterobiasis has not been eradicated in our center. […] To prevent reinfection, general control measures (hand washing, fingernail trimming, daily perineal cleaning, pica control, housekeeping, and the use of long pajamas instead of nightgowns) should be emphasized.
- #43 BugBitten Threadworm: underdiagnosed and underreported in Texas?https://blogs.biomedcentral.com/bugbitten/2021/02/26/threadworm-underdiagnosed-and-underreported-in-texas/
Worm infections are often associated with low and middle income countries, but mounting evidence suggests that intestinal parasites are found in some United States communities. […] However, the true extent and burden of the disease is not well understood. […] This study reports the highest prevalence of S. stercoralis antibody ever recorded in the US. However, the sample size is low. High prevalence has been recorded in some communities in Alabama and institutionalized people. Together these studies suggest threadworms are underreported in the US. There is an opportunity for increasing awareness of this disease within the community and the health care providers for this community and similar communities. There is a need to increase diagnostic effort to identify and effectively treat these diseases, particularly given the high prevalence.
- #44 BugBitten Threadworm: underdiagnosed and underreported in Texas?https://blogs.biomedcentral.com/bugbitten/2021/02/26/threadworm-underdiagnosed-and-underreported-in-texas/
Worm infections are often associated with low and middle income countries, but mounting evidence suggests that intestinal parasites are found in some United States communities. […] However, the true extent and burden of the disease is not well understood. […] This study reports the highest prevalence of S. stercoralis antibody ever recorded in the US. However, the sample size is low. High prevalence has been recorded in some communities in Alabama and institutionalized people. Together these studies suggest threadworms are underreported in the US. There is an opportunity for increasing awareness of this disease within the community and the health care providers for this community and similar communities. There is a need to increase diagnostic effort to identify and effectively treat these diseases, particularly given the high prevalence.
- #45 Do Not Let Pinworms Spoil Your Experimentshttps://www.jax.org/news-and-insights/jax-blog/2015/february/do-not-let-pinworms-spoil-your-experiments
Pinworm outbreaks occur when the parasites take residence in the gastrointestinal tracts of the animals, and although even low-barrier rooms at JAX are pinworm-free, it is a relatively common occurrence in research facilities worldwide. […] Because pinworm eggs are intermittently shed in the feces of infected animals, testing feces at multiple time points or from multiple individuals at a single time point is recommended for more effective surveillance. […] JAX maintains strict protocols for the surveillance and monitoring of pathogenic and opportunistic pathogens in all of our facilities. The last pinworm infection at JAX dates back to the 1970s. Should an outbreak occur, pinworms are one of the pathogens excluded from all JAX mouse rooms, and therefore, all mice shipments would stop to contain the infection.
- #46 Pinworm (threadworm) infectionhttps://www.health.vic.gov.au/infectious-diseases/pinworm-threadworm-infection
The pinworm is the most common helminth parasite of temperate regions. These infections are found worldwide and affect all socioeconomic groups. […] The pinworm is the most common helminth parasite of temperate regions. These infections are found worldwide and affect all socioeconomic groups. […] Pinworm infections predominantly affect paediatric populations, in which the prevalence is reported to be 1050 per cent in some groups. […] Pinworms are transmitted by direct transfer of infected eggs by hand from the anus to the mouth of the same or another person. They can also be transmitted indirectly through bedding, clothing, food or other articles. Spread is facilitated by overcrowding. […] Communicability continues as long as the eggs are being discharged onto the perianal area. The eggs can survive for several days in the right conditions. Reinfection from contaminated hands is common. […] Infection does not confer immunity. […] Public health education on the importance of handwashing may assist. […] Infectious diseases surveillance in Victoria.
- #47 Threadworms: Causes, Symptoms, and Treatmenthttps://patient.info/skin-conditions/itchy-bottom-pruritus-ani/threadworms
Threadworms infect the gut and lay eggs around the anus which causes itchiness. Threadworms are common but do not cause severe problems. […] All household members should be treated at the same time, including those without symptoms. […] If one member of a household is infected, it is common for others also to be infected. So, everyone needs treatment. […] This is why a child may have recurring threadworms, even if the home and personal hygiene are of a very high standard.
- #48 Epidemiology and control of enterobiasis in a developmental centerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1070873/
Enterobiasis is a common and readily transmissible helminthic infection. […] The prevalence of enterobiasis fell rapidly and progressively, from 21% before mass medication to 1% after 3 years. […] Several researchers have experimented with mass medication for enterobiasis, but their studies have been marred by high rates of reinfection, lack of a cost-benefit analysis, short follow-ups, and inadequate surveillance data. […] We describe our positive experience with mass medication, a 3-year follow-up with surveillance, and a financial analysis. […] The initiation of mass medication in 1995 progressively reduced the prevalence from 21% in 1994 to 1% in 1998. […] Our study supports the recommendation of other investigators that for the effective control of enterobiasis, all household contacts should be treated with two anthelminth doses, 14 days apart. […] Despite mass medication, enterobiasis has not been eradicated in our center. […] To prevent reinfection, general control measures (hand washing, fingernail trimming, daily perineal cleaning, pica control, housekeeping, and the use of long pajamas instead of nightgowns) should be emphasized.
- #49 Epidemiology and control of enterobiasis in a developmental centerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1070873/
Enterobiasis is a common and readily transmissible helminthic infection. […] The prevalence of enterobiasis fell rapidly and progressively, from 21% before mass medication to 1% after 3 years. […] Several researchers have experimented with mass medication for enterobiasis, but their studies have been marred by high rates of reinfection, lack of a cost-benefit analysis, short follow-ups, and inadequate surveillance data. […] We describe our positive experience with mass medication, a 3-year follow-up with surveillance, and a financial analysis. […] The initiation of mass medication in 1995 progressively reduced the prevalence from 21% in 1994 to 1% in 1998. […] Our study supports the recommendation of other investigators that for the effective control of enterobiasis, all household contacts should be treated with two anthelminth doses, 14 days apart. […] Despite mass medication, enterobiasis has not been eradicated in our center. […] To prevent reinfection, general control measures (hand washing, fingernail trimming, daily perineal cleaning, pica control, housekeeping, and the use of long pajamas instead of nightgowns) should be emphasized.
- #50 Threadworms: Causes, Symptoms, and Treatmenthttps://patient.info/skin-conditions/itchy-bottom-pruritus-ani/threadworms
Threadworms infect the gut and lay eggs around the anus which causes itchiness. Threadworms are common but do not cause severe problems. […] All household members should be treated at the same time, including those without symptoms. […] If one member of a household is infected, it is common for others also to be infected. So, everyone needs treatment. […] This is why a child may have recurring threadworms, even if the home and personal hygiene are of a very high standard.
- #51 Threadworms: Causes, Symptoms, and Treatmenthttps://patient.info/skin-conditions/itchy-bottom-pruritus-ani/threadworms
Threadworms infect the gut and lay eggs around the anus which causes itchiness. Threadworms are common but do not cause severe problems. […] All household members should be treated at the same time, including those without symptoms. […] If one member of a household is infected, it is common for others also to be infected. So, everyone needs treatment. […] This is why a child may have recurring threadworms, even if the home and personal hygiene are of a very high standard.
- #52 Threadworms have love-hate relationship with carbon dioxide | UCLAhttps://newsroom.ucla.edu/releases/skin-penetrating-nematodes-have-love-hate-relationship-with-carbon-dioxide
Globally, over 600 million people are infected with the skin-penetrating threadworm, Strongyloides stercoralis, mostly in tropical and subtropical regions with poor sanitation infrastructure. […] Infections are treated with ivermectin, but some nematodes are starting to develop resistance to this first-line drug. […] UCLA researchers report that S. stercoralis threadworms respond differently to carbon dioxide at different stages in their life cycle. […] The identification of chemosensory mechanisms that shape the interaction between parasitic nematodes and their human hosts may help scientists design new drugs that target the CO2-sensing pathway.
- #53 Epidemiology and control of enterobiasis in a developmental centerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1070873/
Enterobiasis is a common and readily transmissible helminthic infection. […] The prevalence of enterobiasis fell rapidly and progressively, from 21% before mass medication to 1% after 3 years. […] Several researchers have experimented with mass medication for enterobiasis, but their studies have been marred by high rates of reinfection, lack of a cost-benefit analysis, short follow-ups, and inadequate surveillance data. […] We describe our positive experience with mass medication, a 3-year follow-up with surveillance, and a financial analysis. […] The initiation of mass medication in 1995 progressively reduced the prevalence from 21% in 1994 to 1% in 1998. […] Our study supports the recommendation of other investigators that for the effective control of enterobiasis, all household contacts should be treated with two anthelminth doses, 14 days apart. […] Despite mass medication, enterobiasis has not been eradicated in our center. […] To prevent reinfection, general control measures (hand washing, fingernail trimming, daily perineal cleaning, pica control, housekeeping, and the use of long pajamas instead of nightgowns) should be emphasized.
- #54 Worms fact sheet | NHMRCNHMRCNHMRC TaglineNHMRC Taglinehttps://www.nhmrc.gov.au/about-us/publications/staying-healthy-guidelines/fact-sheets/worms
Ensure staff and children have good hand hygiene, especially after touching animals and before preparing or eating food. […] To minimise the chance of your child getting any kind of worms, make sure they wash their hands thoroughly and often. This is especially important after going to the toilet or touching animals, and before eating.
- #55 Threadworms: Advice for Referrers | NHSGGChttps://clinicalguidelines.scot.nhs.uk/rhc-for-health-professionals/guidelines/primary-care-referral-guidelines/medical-paediatric-pre-referral-guidance/threadworms-advice-for-referrers/
Threadworm (Enterobius Vermicularis) is a parasitic infection that affects the human gut. It is the most common parasitic infection in the UK, usually affecting children under the age of 18 years. […] They are spread via the faecal-oral route when threadworm eggs are ingested. […] The eggs can survive for up to 2 weeks, so repeat infection is common. […] Any previous episodes of threadworm […] Which other members of household, if any, are displaying similar symptoms and if they have been treated. […] Threadworm eggs can survive for up to 2 weeks outside the body on underwear, bedding and other objects. Good hygiene measures will help to clear eggs from the body and home and therefore prevent re-infection. […] If re-infection occurs: Other causes of symptoms should be considered. […] However, in most cases strict hygiene measures have not been adhered to.
- #56 Chronic strongyloidiasis â Donât look and you wonât findhttps://www.racgp.org.au/afp/2016/january-february/chronic-strongyloidiasis-don-t-look-and-you-won-t
Aboriginal and Torres Strait Islander patients from rural and remote areas in Australia should not be given immunosuppressive treatment without being tested or treated prophylactically for strongyloidiasis. […] Control strategies in endemic communities are now possible with improved diagnostic testing and effective treatment regimens. Some health services in endemic communities have incorporated strongyloides serology into biennial adult health checks to ensure better management of patients with chronic strongyloidiasis.
- #57 Enterobius Vermicularis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK536974/
Enterobius vermicularis, also called pinworm, is one of the most common helminth infections in the world, with most cases occurring in children. […] Describe the epidemiology of Enterobius vermicularis infection. […] The male to female infection frequency is 2 to 1. However, a female predominance of infection is seen in those between the ages of 5 and 14 years. It most commonly affects children younger than 18 years of age. It is also commonly seen in adults who take care of children and institutionalized children. Center for Disease Control and Prevention data indicates that there are about 40 million people estimated to have been infected in the United States. Transmission can occur via contact with contaminated clothes, bedding, personal care products, and furniture. Fecal-oral is the most common mode of transmission. Rarely, transmission can occur via inhalation mode when eggs are inhaled and then subsequently swallowed. […] Eradicating pinworms from institutions is very difficult and long term surveillance is required.
- #58 Do Not Let Pinworms Spoil Your Experimentshttps://www.jax.org/news-and-insights/jax-blog/2015/february/do-not-let-pinworms-spoil-your-experiments
Pinworm outbreaks occur when the parasites take residence in the gastrointestinal tracts of the animals, and although even low-barrier rooms at JAX are pinworm-free, it is a relatively common occurrence in research facilities worldwide. […] Because pinworm eggs are intermittently shed in the feces of infected animals, testing feces at multiple time points or from multiple individuals at a single time point is recommended for more effective surveillance. […] JAX maintains strict protocols for the surveillance and monitoring of pathogenic and opportunistic pathogens in all of our facilities. The last pinworm infection at JAX dates back to the 1970s. Should an outbreak occur, pinworms are one of the pathogens excluded from all JAX mouse rooms, and therefore, all mice shipments would stop to contain the infection.
- #59 Threadworms: Causes, Symptoms, and Treatmenthttps://patient.info/skin-conditions/itchy-bottom-pruritus-ani/threadworms
Threadworms infect the gut and lay eggs around the anus which causes itchiness. Threadworms are common but do not cause severe problems. […] All household members should be treated at the same time, including those without symptoms. […] If one member of a household is infected, it is common for others also to be infected. So, everyone needs treatment. […] This is why a child may have recurring threadworms, even if the home and personal hygiene are of a very high standard.
- #60 Is pinworm infection still a public health concern among children in resource-rich regions? Trends in pinworm infection prevalence and associated factors among children in Hualien County, Taiwan: a retrospective cross-sectional study | BMC Public Health |https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-022-14641-4
Enterobius vermicularis (pinworm) is a common intestinal parasitic infection in children. A gradual decrease in the prevalence of pinworm infection has been noted in resource-rich settings, such as Taiwan. […] The overall prevalence of pinworm infection gradually decreased from 2009 to 2018 among school-age children in Hualien. However, there was no declining trend in pinworm infection in rural areas. Pinworm infection remains a major public health concern among children in rural areas of Hualien. […] However, pinworm infection is still an important public health issue in some areas of resource-rich regions, regardless of the decreasing prevalence rates. […] This study revealed the prevalence, time-trend analysis, and associated sociodemographic factors among school-age children in Hualien, Taiwan, from 2009 to 2018. […] The non-obvious decline in the trend of pinworm infection rate in the rural areas of Hualien was an important finding of this study. […] This study highlighted the fact that pinworm infection remains a vital public issue among school-age children in the rural areas of Hualien.
- #61 BugBitten Threadworm: underdiagnosed and underreported in Texas?https://blogs.biomedcentral.com/bugbitten/2021/02/26/threadworm-underdiagnosed-and-underreported-in-texas/
Worm infections are often associated with low and middle income countries, but mounting evidence suggests that intestinal parasites are found in some United States communities. […] However, the true extent and burden of the disease is not well understood. […] This study reports the highest prevalence of S. stercoralis antibody ever recorded in the US. However, the sample size is low. High prevalence has been recorded in some communities in Alabama and institutionalized people. Together these studies suggest threadworms are underreported in the US. There is an opportunity for increasing awareness of this disease within the community and the health care providers for this community and similar communities. There is a need to increase diagnostic effort to identify and effectively treat these diseases, particularly given the high prevalence.
- #62 EMVERM® (mebendazole)âWhat Are Pinworms?https://www.emverm.com/what-are-pinworms/
PINWORM infection is 3x more common than head lice. […] In fact, pinworm is one of the most common parasitic worm infections worldwide and is the most common parasitic worm infection in the United States. […] Pinworm infections happen more often than head lice infestations among young children in the United States. […] In fact, pinworm infection is approximately 3 times more common than head lice.
- #63 Pinworm (threadworm) infectionhttps://www.health.vic.gov.au/infectious-diseases/pinworm-threadworm-infection
The pinworm is the most common helminth parasite of temperate regions. These infections are found worldwide and affect all socioeconomic groups. […] The pinworm is the most common helminth parasite of temperate regions. These infections are found worldwide and affect all socioeconomic groups. […] Pinworm infections predominantly affect paediatric populations, in which the prevalence is reported to be 1050 per cent in some groups. […] Pinworms are transmitted by direct transfer of infected eggs by hand from the anus to the mouth of the same or another person. They can also be transmitted indirectly through bedding, clothing, food or other articles. Spread is facilitated by overcrowding. […] Communicability continues as long as the eggs are being discharged onto the perianal area. The eggs can survive for several days in the right conditions. Reinfection from contaminated hands is common. […] Infection does not confer immunity. […] Public health education on the importance of handwashing may assist. […] Infectious diseases surveillance in Victoria.
- #64 Threadwormshttps://www.nhs.uk/conditions/threadworms/
Threadworms spread when their eggs are swallowed. They lay eggs around your bottom (anus), which make it itchy. The eggs get stuck on your fingers when you scratch. […] Eggs can pass to other people when they touch these surfaces and then touch their mouth. The eggs can survive up to 2 weeks. The larvae hatch from the eggs in your gut after you swallow them, and take 1 to 2 months to mature into threadworms. […] Children can get threadworms again after they’ve been treated for them if they get the eggs in their mouth. This is why it’s important to encourage children to wash their hands regularly.