Materiały źródłowe

• #1 Acute myeloid leukaemia | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/cancer/cancer-types-in-adults/acute-myeloid-leukaemia/

  The symptoms of acute myeloid leukaemia (AML) usually develop over a few weeks, becoming more severe as the number of immature white blood cells (blast cells) in your blood increases. […] Symptoms can include: pale skin, tiredness, breathlessness, a high temperature (fever), excessive sweating, weight loss, frequent infections, unusual and frequent bleeding, such as bleeding gums or nosebleeds, easily bruised skin, flat red or purple spots on the skin (petechiae), bone and joint pain, a feeling of fullness or discomfort in your tummy (abdomen), caused by swelling of the liver or spleen. […] In more advanced cases, AML can make you extremely vulnerable to life-threatening infections or serious internal bleeding. […] If you have AML, you’ll bleed and bruise more easily due to the low levels of platelets (clot-forming cells) in your blood. Bleeding may also be excessive. […] People with advanced AML are more vulnerable to excessive bleeding inside their body, which is the second most common cause of death in people with the condition.

• #2

  https://www.nhs.uk/conditions/acute-myeloid-leukaemia/

  The symptoms of AML usually develop over a few weeks and become worse over time. […] Symptoms can include: […] looking pale or „washed out” […] feeling tired or weak […] breathlessness […] frequent infections […] unusual and frequent bruising or bleeding, such as bleeding gums or nosebleeds […] losing weight without trying to. […] Treatment for AML needs to begin as soon as possible, as it can develop quickly.

• #3 Acute Myeloid Leukemia Treatment – NCI

  https://www.cancer.gov/types/leukemia/patient/adult-aml-treatment-pdq

  Signs and symptoms of AML include fever, feeling tired, and easy bruising or bleeding. […] The early signs and symptoms of AML may be like those caused by the flu or other common diseases. […] Symptoms of acute leukemia often develop between 4 and 6 weeks before diagnosis. […] In AML, there is an increase in the number of immature white blood cells called myeloblasts (or myeloid blasts). […] As the number of these cells, also called leukemia cells, increases in the blood and bone marrow, there is less room for healthy platelets, red blood cells, and other white blood cells. This may lead to easy bleeding, anemia, and infection. […] The leukemia cells can spread outside the blood to other parts of the body, including the central nervous system (CNS; brain and spinal cord), skin, and gums.

• #4 Are there any early signs of acute myeloid leukemia?

  https://www.medicalnewstoday.com/articles/early-signs-of-aml-leukemia

  Without treatment, these symptoms usually develop and worsen rapidly as the number of leukemia cells increase. […] Health experts describe AML as an acute type of leukemia. This term means that it is aggressive and has a rapid onset and progression. A person may not show any symptoms during its early stage but will begin to experience symptoms as the condition advances. […] Typically, symptoms of AML may appear 4-6 weeks before diagnosis. As the condition becomes more advanced, the varying symptoms will become more noticeable. […] AML is an aggressive form of leukemia that can cause a range of symptoms early in the disease process. […] However, these symptoms, such as fever, fatigue, and bone and joint pain, are general, and a person could mistake them for another condition, such as the flu. […] There are currently no screening tests to detect AML early. But it is vital for a person to reach out to a primary care doctor if they are experiencing persistent symptoms, which may indicate the presence of the disease.

• #5 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin (harder to see in darker skin tones), Shortness of breath.

• #6 Acute Myeloid Leukemia Treatment – NCI

  https://www.cancer.gov/types/leukemia/patient/adult-aml-treatment-pdq

  Signs and symptoms of AML include fever, feeling tired, and easy bruising or bleeding. […] The early signs and symptoms of AML may be like those caused by the flu or other common diseases. […] Symptoms of acute leukemia often develop between 4 and 6 weeks before diagnosis. […] In AML, there is an increase in the number of immature white blood cells called myeloblasts (or myeloid blasts). […] As the number of these cells, also called leukemia cells, increases in the blood and bone marrow, there is less room for healthy platelets, red blood cells, and other white blood cells. This may lead to easy bleeding, anemia, and infection. […] The leukemia cells can spread outside the blood to other parts of the body, including the central nervous system (CNS; brain and spinal cord), skin, and gums.

• #7 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin (harder to see in darker skin tones), Shortness of breath.

• #8 Acute Myeloid Leukemia (AML) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/acute-myeloid-leukemia-aml

  Symptoms include fatigue, weakness, weight loss, loss of appetite, fever, shortness of breath. […] In people with AML, symptoms usually develop and progress rapidly over the course of a few weeks. […] Because red blood cells carry oxygen to tissues and organs around the body, people with low levels of red blood cells may have shortness of breath and feel tired. […] Symptoms may include: Feeling tired/weakness, Fever, Shortness of breath, Easy bruising and/or bleeding, Frequent nosebleeds and/or bleeding gums, Heavy menstrual flow in women, Unintentional weight loss, Pale skin, Nosebleeds and/or bleeding gums, Frequent infections, Headache, Bone and joint pain, Tiny red spots on skin (caused by bleeding under the skin), Small bumps, nodules, and/or rash on skin, Vision problems, Abdominal swelling. […] The five-year survival rate for adults with AML in the U.S. is 29.5%. For children and adolescents aged 19 or younger, the five-year survival rate is 66%. APL has a more favorable prognosis than AML and, in the majority of cases, can be cured.

• #9 https://www.lls.org/leukemia/acute-myeloid-leukemia/signs-and-symptoms

  https://www.lls.org/leukemia/acute-myeloid-leukemia/signs-and-symptoms

  The signs and symptoms of acute myeloid leukemia (AML) are common to other, less serious illnesses. However, if you’re troubled by any of the following symptoms, see your doctor: […] It is common for people with AML to feel a loss of well-being because of the underproduction of normal bone marrow cells. […] Symptoms of a low red blood cell count (called anemia) include: Fatigue, Weakness, Shortness of breath during normal physical activities, Lightheadedness, dizziness or faintness, Headaches, Pale complexion. […] Symptoms of a low white blood cell count (called neutropenia) include: Frequent infections, Fever. […] Symptoms of a low platelet count (called thrombocytopenia) include: Bruising easily, Pinhead-sized red spots on the skin, called petechiae, Prolonged bleeding from minor cuts, Frequent or severe nosebleeds, Bleeding gums. […] Other general symptoms of AML include: Loss of appetite, Unexplained weight loss, Discomfort in bones or joints, Fullness or swelling in the abdomen, due to an enlarged spleen or liver.

• #10 Symptoms of acute myeloid leukaemia AML | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/acute-myeloid-leukaemia-aml/symptoms

  Symptoms of AML can be similar to those caused by other illnesses. The symptoms are caused by too many abnormal white blood cells and not enough normal white cells, red cells and platelets. Symptoms of AML might include one or more of the following: feeling weak or tired […] You might feel weaker than normal. […] You might feel more tired than normal, even if you are getting a good night’s sleep. […] You might have a high temperature or feel feverish. […] You might pick up infections such as coughs and colds easily. Or you might find that the infections last a long time and are difficult to shake off. […] You might have: nosebleeds, bleeding gums when you clean your teeth, very heavy periods, small dark red spots on your skin, blood in your wee (urine) or poo (stool). You might find you are bruising more easily than normal.

• #11

  https://www.nhs.uk/conditions/acute-myeloid-leukaemia/symptoms/

  The symptoms of acute myeloid leukaemia (AML) usually develop over a few weeks, becoming more severe as the number of immature white blood cells increases. […] Symptoms of AML can include: skin looking pale or „washed out”, tiredness, breathlessness, losing weight without trying, frequent infections, having a high temperature, and feeling hot or shivery (fever), night sweats, unusual and frequent bleeding, such as bleeding gums or nosebleeds, easily bruised skin, flat red or purple spots on the skin, bone and joint pain, a feeling of fullness or discomfort in your tummy, swollen glands in your neck, armpit or groin that may be sore when you touch them. […] See a GP if you or your child have the symptoms of AML. […] Although it’s highly unlikely that AML is the cause, these symptoms need to be investigated and treated promptly.

• #12 Final Stages of Acute Myeloid Leukemia: Symptoms & Support

  https://www.healthline.com/health/final-stages-of-acute-myeloid-leukemia

  Acute myeloid leukemia (AML) is a progressive type of cancer that affects your bone marrow and blood cells. […] Early detection and treatment are important to help increase the chances of survival from this cancer. See a doctor right away if you notice any possible early symptoms. These include: recurring infections, chronic fever, unusual bleeding. […] Symptoms of the final stages of AML are similar to end-stage symptoms of all types of leukemia. These may include: cool, dry skin, slow or labored breathing, blurry vision, decreased urination or incontinence, restlessness or involuntary muscle movements, decreased movements or weakness, loss of appetite and decreased fluid intake, increased drowsiness and sleepiness, changes in heart rate, signs of bleeding, such as under the skin (petechiae) or from the nose, pain, hallucinations, confusion, loss of consciousness.

• #13 Symptoms of acute myeloid leukaemia AML | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/acute-myeloid-leukaemia-aml/symptoms

  You might notice that you’re feeling breathless more than usual or for a lot of the time. You might feel out of breath after your normal day to day activities or from climbing a short flight of stairs. This could be because you do not have enough red blood cells (anaemia). […] You might lose weight even if you haven’t changed your diet. […] You might feel pain in your bones or joints. This might be a dull ache or more of a stabbing pain. It might be worse at different times of the day. […] You might have a feeling of fullness or discomfort in your tummy (abdomen). This can happen if your liver or spleen are swollen. […] You might look paler or more 'washed out’ than normal. This could also be because you do not have enough red blood cells. […] Less common symptoms include lumps on the skin and swollen lymph nodes. Your lymph nodes (glands) might feel swollen when you touch them. You have lymph nodes in lots of places in your body. They might feel swollen in: your neck, under your armpit, in your groin. […] The symptoms of AML are often vague and can be caused by other medical conditions. The earlier an acute leukaemia is picked up, the easier it is to treat and the more likely treatment is to be successful. So go to your GP as soon as possible.

• #14 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Acute myeloid leukemia (AML) is a type of blood cancer that starts in your bone marrow, which is the soft inner part of your bones where all your blood cells are made. […] People with AML may develop general or nonspecific symptoms. These symptoms are nonspecific because they can be caused by several other conditions. Such symptoms include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] When you have AML, the abnormal myeloid blast cells can crowd out the other cells in your bone marrow that make blood cells. This can prevent your bone marrow from making enough red blood cells, white blood cells, and platelets to feel healthy. […] Symptoms of low red blood cell counts (anemia) include: Fatigue (extreme tiredness), Weakness, Feeling cold, Feeling lightheaded or dizzy, Headaches, Pale skin, Shortness of breath.

• #15 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin (harder to see in darker skin tones), Shortness of breath.

• #16 https://www.lls.org/leukemia/acute-myeloid-leukemia/signs-and-symptoms

  https://www.lls.org/leukemia/acute-myeloid-leukemia/signs-and-symptoms

  The signs and symptoms of acute myeloid leukemia (AML) are common to other, less serious illnesses. However, if you’re troubled by any of the following symptoms, see your doctor: […] It is common for people with AML to feel a loss of well-being because of the underproduction of normal bone marrow cells. […] Symptoms of a low red blood cell count (called anemia) include: Fatigue, Weakness, Shortness of breath during normal physical activities, Lightheadedness, dizziness or faintness, Headaches, Pale complexion. […] Symptoms of a low white blood cell count (called neutropenia) include: Frequent infections, Fever. […] Symptoms of a low platelet count (called thrombocytopenia) include: Bruising easily, Pinhead-sized red spots on the skin, called petechiae, Prolonged bleeding from minor cuts, Frequent or severe nosebleeds, Bleeding gums. […] Other general symptoms of AML include: Loss of appetite, Unexplained weight loss, Discomfort in bones or joints, Fullness or swelling in the abdomen, due to an enlarged spleen or liver.

• #17 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin (harder to see in darker skin tones), Shortness of breath.

• #18 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  About blood cancer […] Acute myeloid leukaemia (AML) symptoms and tests […] There are many possible symptoms of AML, but not everyone will get every symptom. […] Many AML symptoms are caused by not having enough healthy blood cells of each type. […] This is caused by a lack of red blood cells, which carry oxygen around the body. If your number of red blood cells is low, its called anaemia. […] Anaemia causes: tiredness, weakness or lack of energy, which you feel much more than usual […] breathlessness, which you might notice when you try to do something like walking, shopping or housework […] feeling dizzy, light-headed or having headaches […] chest pain, although this is a rarer symptom […] paleness (pallor), which can be seen by pulling down your lower eyelid (the inside will look white or pale pink, rather than dark pink or red).

• #19 https://www.lls.org/leukemia/acute-myeloid-leukemia/signs-and-symptoms

  https://www.lls.org/leukemia/acute-myeloid-leukemia/signs-and-symptoms

  The signs and symptoms of acute myeloid leukemia (AML) are common to other, less serious illnesses. However, if you’re troubled by any of the following symptoms, see your doctor: […] It is common for people with AML to feel a loss of well-being because of the underproduction of normal bone marrow cells. […] Symptoms of a low red blood cell count (called anemia) include: Fatigue, Weakness, Shortness of breath during normal physical activities, Lightheadedness, dizziness or faintness, Headaches, Pale complexion. […] Symptoms of a low white blood cell count (called neutropenia) include: Frequent infections, Fever. […] Symptoms of a low platelet count (called thrombocytopenia) include: Bruising easily, Pinhead-sized red spots on the skin, called petechiae, Prolonged bleeding from minor cuts, Frequent or severe nosebleeds, Bleeding gums. […] Other general symptoms of AML include: Loss of appetite, Unexplained weight loss, Discomfort in bones or joints, Fullness or swelling in the abdomen, due to an enlarged spleen or liver.

• #20 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Acute myeloid leukemia (AML) is a type of blood cancer that starts in your bone marrow, which is the soft inner part of your bones where all your blood cells are made. […] People with AML may develop general or nonspecific symptoms. These symptoms are nonspecific because they can be caused by several other conditions. Such symptoms include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] When you have AML, the abnormal myeloid blast cells can crowd out the other cells in your bone marrow that make blood cells. This can prevent your bone marrow from making enough red blood cells, white blood cells, and platelets to feel healthy. […] Symptoms of low red blood cell counts (anemia) include: Fatigue (extreme tiredness), Weakness, Feeling cold, Feeling lightheaded or dizzy, Headaches, Pale skin, Shortness of breath.

• #21 Symptoms of acute myeloid leukaemia AML | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/acute-myeloid-leukaemia-aml/symptoms

  You might notice that you’re feeling breathless more than usual or for a lot of the time. You might feel out of breath after your normal day to day activities or from climbing a short flight of stairs. This could be because you do not have enough red blood cells (anaemia). […] You might lose weight even if you haven’t changed your diet. […] You might feel pain in your bones or joints. This might be a dull ache or more of a stabbing pain. It might be worse at different times of the day. […] You might have a feeling of fullness or discomfort in your tummy (abdomen). This can happen if your liver or spleen are swollen. […] You might look paler or more 'washed out’ than normal. This could also be because you do not have enough red blood cells. […] Less common symptoms include lumps on the skin and swollen lymph nodes. Your lymph nodes (glands) might feel swollen when you touch them. You have lymph nodes in lots of places in your body. They might feel swollen in: your neck, under your armpit, in your groin. […] The symptoms of AML are often vague and can be caused by other medical conditions. The earlier an acute leukaemia is picked up, the easier it is to treat and the more likely treatment is to be successful. So go to your GP as soon as possible.

• #22 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://my.clevelandclinic.org/health/diseases/6212-acute-myeloid-leukemia-aml

  Acute myeloid leukemia (AML) is a rare cancer that affects your bone marrow and blood. Its an aggressive cancer that, left untreated, may be life-threatening. AML typically affects people age 60 and older, but it can affect younger adults and children. […] Early on, AML symptoms may feel like you have a cold or flu that wont go away. Acute myeloid leukemia is aggressive. That means you quickly develop new and more noticeable symptoms. Later symptoms include: Dizziness. Easy bruising or bleeding, including frequent nosebleeds and bleeding gums. Fatigue. Feeling cold. Fever. Night sweats. Frequent infections or infections that dont go away. Headaches. Loss of appetite. Unexplained weight loss. Pale skin. Shortness of breath (dyspnea). Swollen lymph nodes. Weakness. Bone, back or abdominal pain. Tiny red spots on your skin (petechiae). Wounds or sores that dont go away.

• #23 Acute myeloid leukaemia | Leukaemia & Blood Cancer New Zealand

  https://www.leukaemia.org.nz/information/about-blood-cancers/leukaemia/acute-myeloid-leukaemia/

  Anaemia (low haemoglobin) […] Lack of energy (lethargy) […] Feeling tired all the time (fatigue) […] Shortness of breath, especially when exercising […] Dizziness […] Pale skin. […] Bleeding and bruising (low platelet count) […] Bruising easily […] Minor cuts or injuries that take a long time to stop bleeding […] Frequent or severe nosebleeds or bleeding gums […] Red or purple pinhead-sized spots on the skin called petechiae […] Heavier or more frequent menstrual periods. […] Infections […] Common signs and symptoms of infection include: […] Fever (high temperature) […] Shivering or rigours […] Coughing up yellow or green phlegm […] Fatigue or extreme tiredness. […] Other symptoms of AML […] Bone pain […] Swollen lymph nodes […] Swollen gums […] Chest pain […] Sore stomach area.

• #24 Acute Myeloid Leukemia: AML Symptoms, Treatment & Survival Rate

  https://www.cancercenter.com/cancer-types/leukemia/types/acute-myeloid-leukemia

  Easy bleeding or bruising: Platelets control bleeding. Having low levels in the blood can lead to easy bleeding or bruising. This can result in the slow healing of cuts, prolonged bleeding from minor cuts and bruises with no clear cause. It can also lead to petechiae, tiny red spots under the skin. […] Joint and bone pain: The increased number of leukemia cells can cause pain in bones, joints or both. […] Dizziness: Patients with a low red blood cell count may feel lightheaded or dizzy. […] Fatigue: Low level of healthy blood cells may result in feeling tired and run down. […] Night sweats: One general symptom of AML may include waking up feeling sweaty during the night. […] Feeling cold: Patients with a low red blood cell count may frequently feel cold. […] Weight loss: A nonspecific symptom of AML may include unexplained weight loss.

• #25 Acute myeloid leukaemia | Leukaemia & Blood Cancer New Zealand

  https://www.leukaemia.org.nz/information/about-blood-cancers/leukaemia/acute-myeloid-leukaemia/

  Anaemia (low haemoglobin) […] Lack of energy (lethargy) […] Feeling tired all the time (fatigue) […] Shortness of breath, especially when exercising […] Dizziness […] Pale skin. […] Bleeding and bruising (low platelet count) […] Bruising easily […] Minor cuts or injuries that take a long time to stop bleeding […] Frequent or severe nosebleeds or bleeding gums […] Red or purple pinhead-sized spots on the skin called petechiae […] Heavier or more frequent menstrual periods. […] Infections […] Common signs and symptoms of infection include: […] Fever (high temperature) […] Shivering or rigours […] Coughing up yellow or green phlegm […] Fatigue or extreme tiredness. […] Other symptoms of AML […] Bone pain […] Swollen lymph nodes […] Swollen gums […] Chest pain […] Sore stomach area.

• #26 Acute Myeloid Leukemia (AML): Symptoms | UMass Memorial Health

  https://www.ummhealth.org/health-library/acute-myeloid-leukemia-aml-symptoms

  Symptoms of AML can be different in each person. The most common symptoms include: Bleeding that’s hard to stop. Easy bruising. Fever. Frequent infections or infections that keep coming back. Feeling weak. Feeling very tired (fatigue). Pale skin. Shortness of breath. Chest pain. Dizziness. Headaches. Blurred vision. Aches in back, bones, and joints. Swollen or bleeding gums. Swollen lymph nodes, liver, or spleen. Loss of appetite. Unplanned weight loss. Rashes of tiny flat red or purple spots under the skin (caused by bleeding). Sores or wounds that don’t heal. Night sweats. Heavy periods, more frequent periods, or periods that last longer than normal. […] Many of these symptoms can be caused by other, more common health problems. In fact, most of them are more likely to be caused by something else. Still, it’s important to see a doctor if you have these symptoms. Only a doctor can tell if you have AML, another type of cancer, or some other medical problem that needs to be treated.

• #27 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin (harder to see in darker skin tones), Shortness of breath.

• #28 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Acute myeloid leukemia (AML) is a type of blood cancer that starts in your bone marrow, which is the soft inner part of your bones where all your blood cells are made. […] People with AML may develop general or nonspecific symptoms. These symptoms are nonspecific because they can be caused by several other conditions. Such symptoms include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] When you have AML, the abnormal myeloid blast cells can crowd out the other cells in your bone marrow that make blood cells. This can prevent your bone marrow from making enough red blood cells, white blood cells, and platelets to feel healthy. […] Symptoms of low red blood cell counts (anemia) include: Fatigue (extreme tiredness), Weakness, Feeling cold, Feeling lightheaded or dizzy, Headaches, Pale skin, Shortness of breath.

• #29 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Acute myeloid leukemia (AML) is a type of blood cancer that starts in your bone marrow, which is the soft inner part of your bones where all your blood cells are made. […] People with AML may develop general or nonspecific symptoms. These symptoms are nonspecific because they can be caused by several other conditions. Such symptoms include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] When you have AML, the abnormal myeloid blast cells can crowd out the other cells in your bone marrow that make blood cells. This can prevent your bone marrow from making enough red blood cells, white blood cells, and platelets to feel healthy. […] Symptoms of low red blood cell counts (anemia) include: Fatigue (extreme tiredness), Weakness, Feeling cold, Feeling lightheaded or dizzy, Headaches, Pale skin, Shortness of breath.

• #30 Acute Myeloid Leukemia: AML Symptoms, Treatment & Survival Rate

  https://www.cancercenter.com/cancer-types/leukemia/types/acute-myeloid-leukemia

  Easy bleeding or bruising: Platelets control bleeding. Having low levels in the blood can lead to easy bleeding or bruising. This can result in the slow healing of cuts, prolonged bleeding from minor cuts and bruises with no clear cause. It can also lead to petechiae, tiny red spots under the skin. […] Joint and bone pain: The increased number of leukemia cells can cause pain in bones, joints or both. […] Dizziness: Patients with a low red blood cell count may feel lightheaded or dizzy. […] Fatigue: Low level of healthy blood cells may result in feeling tired and run down. […] Night sweats: One general symptom of AML may include waking up feeling sweaty during the night. […] Feeling cold: Patients with a low red blood cell count may frequently feel cold. […] Weight loss: A nonspecific symptom of AML may include unexplained weight loss.

• #31 Acute Myelogenous Leukemia (AML) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/acute-myelogenous-leukemia-aml

  The most common signs and symptoms of acute myelogenous leukemia in children are: […] Anemia occurs when normal red blood cells can’t be produced because the bone marrow is overcrowded by leukemia cells. The anemic child may be more tired, take more naps, look pale, and her heart may be racing. […] When the bone marrow cannot produce enough platelets, bleeding can occur, especially when the platelet numbers are less than 10-20,000/mm3. Low platelets can cause a child to bruise or bleed more easily. […] Pain in bones and joints is usually a result of the bone marrow being crowded with leukemic blasts. This is often mistaken for „growing pains.” […] The child with leukemia often shows non-specific symptoms of infection such as fever and fatigue. Although the blood count of a child with leukemia may show a high number of white blood cells, these cells are immature and do not normally fight infection. As a result, the child may have difficulty recovering from an ordinary childhood infection or may develop unusual infections.

• #32 What Are the Symptoms of Acute Myeloid Leukemia?

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-complications

  Acute myeloid leukemia (AML) is a cancer of immature blood cells. In the early stages of AML, as your body makes fewer healthy blood cells, you might feel like you’ve come down with the flu or get sick from infections more easily than normal. Symptoms can include: Tiredness, Fever, Loss of appetite, Weight loss, Night sweats. […] If you have fewer healthy red blood cells than normal, you’ll have symptoms like these: Tiredness, Weakness, Pale skin, Irregular heartbeat, Dizziness, Cold hands and feet, Shortness of breath, Headaches, Weight loss, Loss of appetite. […] If you have fewer healthy white blood cells than normal, you may get more infections than usual. These infections may take a long time to get better. Infections can cause symptoms like these: Fever, Weakness, Achy muscles, Fatigue, Diarrhea.

• #33 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another. […] A shortage of blood platelets is called thrombocytopenia. This can lead to: Bruises (or small red or purple spots) on the skin, Excess bleeding, Frequent or severe nosebleeds, Bleeding gums, Heavy periods (menstrual bleeding) in women. […] The cancer cells in AML (called blasts) are bigger than normal blood cells and have more trouble traveling through tiny blood vessels. If the blast count gets very high, these cells can clog up blood vessels and make it hard for normal red blood cells (and oxygen) to get to tissues. This is called leukostasis.

• #34 https://www.lls.org/leukemia/acute-myeloid-leukemia/signs-and-symptoms

  https://www.lls.org/leukemia/acute-myeloid-leukemia/signs-and-symptoms

  The signs and symptoms of acute myeloid leukemia (AML) are common to other, less serious illnesses. However, if you’re troubled by any of the following symptoms, see your doctor: […] It is common for people with AML to feel a loss of well-being because of the underproduction of normal bone marrow cells. […] Symptoms of a low red blood cell count (called anemia) include: Fatigue, Weakness, Shortness of breath during normal physical activities, Lightheadedness, dizziness or faintness, Headaches, Pale complexion. […] Symptoms of a low white blood cell count (called neutropenia) include: Frequent infections, Fever. […] Symptoms of a low platelet count (called thrombocytopenia) include: Bruising easily, Pinhead-sized red spots on the skin, called petechiae, Prolonged bleeding from minor cuts, Frequent or severe nosebleeds, Bleeding gums. […] Other general symptoms of AML include: Loss of appetite, Unexplained weight loss, Discomfort in bones or joints, Fullness or swelling in the abdomen, due to an enlarged spleen or liver.

• #35

  https://www.nhs.uk/conditions/acute-myeloid-leukaemia/symptoms/

  The symptoms of acute myeloid leukaemia (AML) usually develop over a few weeks, becoming more severe as the number of immature white blood cells increases. […] Symptoms of AML can include: skin looking pale or „washed out”, tiredness, breathlessness, losing weight without trying, frequent infections, having a high temperature, and feeling hot or shivery (fever), night sweats, unusual and frequent bleeding, such as bleeding gums or nosebleeds, easily bruised skin, flat red or purple spots on the skin, bone and joint pain, a feeling of fullness or discomfort in your tummy, swollen glands in your neck, armpit or groin that may be sore when you touch them. […] See a GP if you or your child have the symptoms of AML. […] Although it’s highly unlikely that AML is the cause, these symptoms need to be investigated and treated promptly.

• #36 Acute myeloid leukaemia | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/cancer/cancer-types-in-adults/acute-myeloid-leukaemia/

  The symptoms of acute myeloid leukaemia (AML) usually develop over a few weeks, becoming more severe as the number of immature white blood cells (blast cells) in your blood increases. […] Symptoms can include: pale skin, tiredness, breathlessness, a high temperature (fever), excessive sweating, weight loss, frequent infections, unusual and frequent bleeding, such as bleeding gums or nosebleeds, easily bruised skin, flat red or purple spots on the skin (petechiae), bone and joint pain, a feeling of fullness or discomfort in your tummy (abdomen), caused by swelling of the liver or spleen. […] In more advanced cases, AML can make you extremely vulnerable to life-threatening infections or serious internal bleeding. […] If you have AML, you’ll bleed and bruise more easily due to the low levels of platelets (clot-forming cells) in your blood. Bleeding may also be excessive. […] People with advanced AML are more vulnerable to excessive bleeding inside their body, which is the second most common cause of death in people with the condition.

• #37 Acute myeloid leukaemia | Leukaemia & Blood Cancer New Zealand

  https://www.leukaemia.org.nz/information/about-blood-cancers/leukaemia/acute-myeloid-leukaemia/

  Anaemia (low haemoglobin) […] Lack of energy (lethargy) […] Feeling tired all the time (fatigue) […] Shortness of breath, especially when exercising […] Dizziness […] Pale skin. […] Bleeding and bruising (low platelet count) […] Bruising easily […] Minor cuts or injuries that take a long time to stop bleeding […] Frequent or severe nosebleeds or bleeding gums […] Red or purple pinhead-sized spots on the skin called petechiae […] Heavier or more frequent menstrual periods. […] Infections […] Common signs and symptoms of infection include: […] Fever (high temperature) […] Shivering or rigours […] Coughing up yellow or green phlegm […] Fatigue or extreme tiredness. […] Other symptoms of AML […] Bone pain […] Swollen lymph nodes […] Swollen gums […] Chest pain […] Sore stomach area.

• #38 Childhood Acute Myeloid Leukemia (AML)| LLS.org

  https://www.lls.org/leukemia/acute-myeloid-leukemia/childhood-aml/signs-and-symptoms

  It is common for children with AML to feel a loss of well-being because of the underproduction of normal bone marrow cells. […] Symptoms of a low red blood cell count (called anemia) include the following: Fatigue, Weakness, Shortness of breath during normal physical activities, Lightheadedness, dizziness or faintness, Headaches, Pale complexion. […] Symptoms of a low white blood cell count (called neutropenia) include the following: Frequent infections, Recurrent fevers. […] Symptoms of a low platelet count (called thrombocytopenia) include the following: Bruising easily, Pinhead-sized red spots on the skin, called petechiae, Bleeding that is hard to stop, even from a small cut, Frequent or severe nosebleeds, Bleeding gums, Heavier or more frequent menstrual periods. […] Other general symptoms of AML include the following: Unexplained weight loss or loss of appetite, Swollen glands, Bone and joint pain, Difficulty breathing, Enlarged spleen or liver. […] The signs and symptoms of acute myeloid leukemia (AML) are common to other, less serious illnesses. However, if your child is troubled by any of the symptoms above, see a pediatrician.

• #39 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://my.clevelandclinic.org/health/diseases/6212-acute-myeloid-leukemia-aml

  Acute myeloid leukemia (AML) is a rare cancer that affects your bone marrow and blood. Its an aggressive cancer that, left untreated, may be life-threatening. AML typically affects people age 60 and older, but it can affect younger adults and children. […] Early on, AML symptoms may feel like you have a cold or flu that wont go away. Acute myeloid leukemia is aggressive. That means you quickly develop new and more noticeable symptoms. Later symptoms include: Dizziness. Easy bruising or bleeding, including frequent nosebleeds and bleeding gums. Fatigue. Feeling cold. Fever. Night sweats. Frequent infections or infections that dont go away. Headaches. Loss of appetite. Unexplained weight loss. Pale skin. Shortness of breath (dyspnea). Swollen lymph nodes. Weakness. Bone, back or abdominal pain. Tiny red spots on your skin (petechiae). Wounds or sores that dont go away.

• #40 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Symptoms of low white blood cell counts include: Infections that don’t seem to go away, Back-to-back infections, Fever. […] Symptoms of low platelet counts include: Bruises on your skin, including small red or purple spots called petechiae, Bleeding from your gums, Frequent or severe nosebleeds, Bleeding excessively, Heavy bleeding during your menstrual period. […] If you have a type of AML called acute promyelocytic leukemia (APL), you may have problems with bleeding or blood clotting. […] When you have AML, your bone marrow makes abnormal cells called myeloid blasts. These cells are bigger than normal white blood cells, so they have trouble moving through your smaller blood vessels. If you have high levels of these myeloid blasts, they may block the flow in small blood vessels. This may make it hard for your red blood cells to deliver oxygen to all your tissues. This is called leukostasis, and it’s a rare symptom of AML.

• #41 Symptoms of Acute Myeloid Leukaemia (AML) | Cancer Council NSW

  https://www.cancercouncil.com.au/acute-myeloid-leukaemia/symptoms/

  Occasionally, a person will have no symptoms or vague symptoms such as an ongoing cold, and the leukaemia is discovered during a routine blood test. Usually, people with acute myeloid leukaemia (AML) find that some of the following symptoms appear quickly over a few weeks. […] Low levels of red blood cells (anaemia) can cause tiredness (fatigue), weakness, a pale complexion and breathlessness. […] Low platelet levels can cause bruising without a bump or fall, nosebleeds, bleeding gums, heavy periods, and small red or purple spots on the skin or mouth (called petechiae). […] A lack of normal white blood cells can cause mouth sores or ulcers, sore throats, fevers, sweats, coughing, boils, infected cuts or scratches, and frequent and painful passing of urine. A low white blood cell level can also lead to more serious infections.

• #42 Acute Myeloid Leukaemia (AML): Symptoms, Causes & Treatment | Metropolis TruHealth Blog

  https://www.metropolisindia.com/blog/health-wellness/learn-about-acute-myeloid-leukaemia

  Acute myeloid leukaemia (AML) is a type of blood cancer that starts in the bone marrow or the soft, internal section of a bone. […] White blood cells help the body fight infections, but in people with AML, these white blood cells fail to grow properly and subsequently transform into cancer cells called myeloid blasts. These then move from the bone marrow into the bloodstream, affecting various other body parts. […] If acute myeloid leukaemia symptoms are left untreated, the cancer can spread to the brain, lymph nodes, liver, spleen, skin, and cerebral spinal fluid. […] In its early stages, the signs of acute myeloid leukaemia can be the same as flu, and you might suffer from fatigue and fever. Other common symptoms of AML include: Frequent nosebleeds, Bone pain, Easy bruising, Swollen and bleeding gums, Shortness of breath, Excessive sweating, especially at night, Unexplained weight loss, Fatigue, Fever, Heavier than normal periods in women, Headaches, Dizziness, Weakness, Feeling cold all the time, Joint pain, Vomiting.

• #43 Acute myeloid leukaemia | Leukaemia & Blood Cancer New Zealand

  https://www.leukaemia.org.nz/information/about-blood-cancers/leukaemia/acute-myeloid-leukaemia/

  Anaemia (low haemoglobin) […] Lack of energy (lethargy) […] Feeling tired all the time (fatigue) […] Shortness of breath, especially when exercising […] Dizziness […] Pale skin. […] Bleeding and bruising (low platelet count) […] Bruising easily […] Minor cuts or injuries that take a long time to stop bleeding […] Frequent or severe nosebleeds or bleeding gums […] Red or purple pinhead-sized spots on the skin called petechiae […] Heavier or more frequent menstrual periods. […] Infections […] Common signs and symptoms of infection include: […] Fever (high temperature) […] Shivering or rigours […] Coughing up yellow or green phlegm […] Fatigue or extreme tiredness. […] Other symptoms of AML […] Bone pain […] Swollen lymph nodes […] Swollen gums […] Chest pain […] Sore stomach area.

• #44 12 Top Acute Myeloid Leukemia Symptoms & Signs | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/acute-myeloid-leukemia/acute-myeloid-leukemia-symptoms.html

  Weakness, tiredness and fatigue. This can be caused by the leukemia itself or by the low levels of hemoglobin seen in many leukemia patients. […] Fever and frequent infections due to low counts of health white blood cells. […] Excessive sweating or night sweats […] Easy bleeding and bruising, including bleeding of the gums due to low platelet levels. […] Recurrent nose bleeds […] Petechiae, a rash-like collection of pinpoint spots on the skin caused by bleeding into the skin. This is also due to low levels of platelets. […] Shortness of breath. This can be caused by low hemoglobin levels and lung infections. […] Swollen lymph nodes in the neck, underarm, stomach or groin […] Loss of appetite or a full feeling after eating very little food due to enlargement of the spleen […] Unexplained weight loss […] Bone and joint pain […] For female patients, longer than normal or heavier than normal menstruation.

• #45 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  Many people with AML get fatigue a kind of tiredness that makes you feel suddenly drained. […] This is caused by a lack of platelets, which help the blood to clot and prevent bleeding. If your number of platelets is low (also called thrombocytopenia), this can cause: bruising more easily, even if you havent had a bump or injury […] tiny spots (petechiae) or larger blotches (purpura) on the skin […] bleeding from your gums or nose […] more bleeding than expected from a cut […] heavier periods (menstrual bleeding) […] blood in your wee or poo, or very black and tarry poo […] rarely, neurological symptoms like visual changes, confusion, vomiting, loss of muscle control or seizures if there is bleeding in the brain. […] This is caused by a lack of healthy white blood cells, which help fight off infections in the body. Without fully functioning white blood cells, germs including bacteria, viruses and fungi (yeasts and moulds) that wouldnt normally be a problem can become serious infections.

• #46 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Symptoms of low white blood cell counts include: Infections that don’t seem to go away, Back-to-back infections, Fever. […] Symptoms of low platelet counts include: Bruises on your skin, including small red or purple spots called petechiae, Bleeding from your gums, Frequent or severe nosebleeds, Bleeding excessively, Heavy bleeding during your menstrual period. […] If you have a type of AML called acute promyelocytic leukemia (APL), you may have problems with bleeding or blood clotting. […] When you have AML, your bone marrow makes abnormal cells called myeloid blasts. These cells are bigger than normal white blood cells, so they have trouble moving through your smaller blood vessels. If you have high levels of these myeloid blasts, they may block the flow in small blood vessels. This may make it hard for your red blood cells to deliver oxygen to all your tissues. This is called leukostasis, and it’s a rare symptom of AML.

• #47 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another. […] A shortage of blood platelets is called thrombocytopenia. This can lead to: Bruises (or small red or purple spots) on the skin, Excess bleeding, Frequent or severe nosebleeds, Bleeding gums, Heavy periods (menstrual bleeding) in women. […] The cancer cells in AML (called blasts) are bigger than normal blood cells and have more trouble traveling through tiny blood vessels. If the blast count gets very high, these cells can clog up blood vessels and make it hard for normal red blood cells (and oxygen) to get to tissues. This is called leukostasis.

• #48 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  If you have AML and you get any symptoms of an infection (sometimes this might only be a high temperature), you should get urgent medical help, because there is a risk of developing life-threatening sepsis. […] Having a low white blood cell count can cause: repeated infections […] infections that are hard to get rid of […] fever (high temperature) […] infections such as pneumonia, urinary tract infections (UTIs) or gastroenteritis. […] Some people with AML have bone pain or joint pain caused by the build-up of leukaemia cells in these areas. […] We dont fully understand the link between AML and weight loss, but losing weight without changing your diet is a symptom of AML and other types of cancer. […] If AML develops very quickly, you might suddenly have very high numbers of faulty white blood cells (leukaemia cells) in your blood. This is known as leukostasis. It can cause the blood to flow less well, and blood vessels can get blocked.

• #49 Symptoms of acute myeloid leukaemia AML | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/acute-myeloid-leukaemia-aml/symptoms

  Symptoms of AML can be similar to those caused by other illnesses. The symptoms are caused by too many abnormal white blood cells and not enough normal white cells, red cells and platelets. Symptoms of AML might include one or more of the following: feeling weak or tired […] You might feel weaker than normal. […] You might feel more tired than normal, even if you are getting a good night’s sleep. […] You might have a high temperature or feel feverish. […] You might pick up infections such as coughs and colds easily. Or you might find that the infections last a long time and are difficult to shake off. […] You might have: nosebleeds, bleeding gums when you clean your teeth, very heavy periods, small dark red spots on your skin, blood in your wee (urine) or poo (stool). You might find you are bruising more easily than normal.

• #50 Acute myeloid leukaemia | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/cancer/cancer-types-in-adults/acute-myeloid-leukaemia/

  The symptoms of acute myeloid leukaemia (AML) usually develop over a few weeks, becoming more severe as the number of immature white blood cells (blast cells) in your blood increases. […] Symptoms can include: pale skin, tiredness, breathlessness, a high temperature (fever), excessive sweating, weight loss, frequent infections, unusual and frequent bleeding, such as bleeding gums or nosebleeds, easily bruised skin, flat red or purple spots on the skin (petechiae), bone and joint pain, a feeling of fullness or discomfort in your tummy (abdomen), caused by swelling of the liver or spleen. […] In more advanced cases, AML can make you extremely vulnerable to life-threatening infections or serious internal bleeding. […] If you have AML, you’ll bleed and bruise more easily due to the low levels of platelets (clot-forming cells) in your blood. Bleeding may also be excessive. […] People with advanced AML are more vulnerable to excessive bleeding inside their body, which is the second most common cause of death in people with the condition.

• #51 Symptoms of acute myeloid leukaemia AML | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/acute-myeloid-leukaemia-aml/symptoms

  Symptoms of AML can be similar to those caused by other illnesses. The symptoms are caused by too many abnormal white blood cells and not enough normal white cells, red cells and platelets. Symptoms of AML might include one or more of the following: feeling weak or tired […] You might feel weaker than normal. […] You might feel more tired than normal, even if you are getting a good night’s sleep. […] You might have a high temperature or feel feverish. […] You might pick up infections such as coughs and colds easily. Or you might find that the infections last a long time and are difficult to shake off. […] You might have: nosebleeds, bleeding gums when you clean your teeth, very heavy periods, small dark red spots on your skin, blood in your wee (urine) or poo (stool). You might find you are bruising more easily than normal.

• #52 Acute Myeloid Leukemia (AML) (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/aml.html

  Because their white blood cells can’t fight infections, kids with leukemia are more likely to get viral or bacterial infections. […] Sometimes leukemia can spread, or metastasize. If it spreads to the brain, symptoms may include headaches, seizures, balance problems, or vision problems. If it spreads to the lymph nodes in the chest, symptoms can include breathing problems and chest pain.

• #53 Childhood Acute Myeloid Leukemia (AML)| LLS.org

  https://www.lls.org/leukemia/acute-myeloid-leukemia/childhood-aml/signs-and-symptoms

  It is common for children with AML to feel a loss of well-being because of the underproduction of normal bone marrow cells. […] Symptoms of a low red blood cell count (called anemia) include the following: Fatigue, Weakness, Shortness of breath during normal physical activities, Lightheadedness, dizziness or faintness, Headaches, Pale complexion. […] Symptoms of a low white blood cell count (called neutropenia) include the following: Frequent infections, Recurrent fevers. […] Symptoms of a low platelet count (called thrombocytopenia) include the following: Bruising easily, Pinhead-sized red spots on the skin, called petechiae, Bleeding that is hard to stop, even from a small cut, Frequent or severe nosebleeds, Bleeding gums, Heavier or more frequent menstrual periods. […] Other general symptoms of AML include the following: Unexplained weight loss or loss of appetite, Swollen glands, Bone and joint pain, Difficulty breathing, Enlarged spleen or liver. […] The signs and symptoms of acute myeloid leukemia (AML) are common to other, less serious illnesses. However, if your child is troubled by any of the symptoms above, see a pediatrician.

• #54 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://my.clevelandclinic.org/health/diseases/6212-acute-myeloid-leukemia-aml

  Acute myeloid leukemia (AML) is a rare cancer that affects your bone marrow and blood. Its an aggressive cancer that, left untreated, may be life-threatening. AML typically affects people age 60 and older, but it can affect younger adults and children. […] Early on, AML symptoms may feel like you have a cold or flu that wont go away. Acute myeloid leukemia is aggressive. That means you quickly develop new and more noticeable symptoms. Later symptoms include: Dizziness. Easy bruising or bleeding, including frequent nosebleeds and bleeding gums. Fatigue. Feeling cold. Fever. Night sweats. Frequent infections or infections that dont go away. Headaches. Loss of appetite. Unexplained weight loss. Pale skin. Shortness of breath (dyspnea). Swollen lymph nodes. Weakness. Bone, back or abdominal pain. Tiny red spots on your skin (petechiae). Wounds or sores that dont go away.

• #55 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  If you have AML and you get any symptoms of an infection (sometimes this might only be a high temperature), you should get urgent medical help, because there is a risk of developing life-threatening sepsis. […] Having a low white blood cell count can cause: repeated infections […] infections that are hard to get rid of […] fever (high temperature) […] infections such as pneumonia, urinary tract infections (UTIs) or gastroenteritis. […] Some people with AML have bone pain or joint pain caused by the build-up of leukaemia cells in these areas. […] We dont fully understand the link between AML and weight loss, but losing weight without changing your diet is a symptom of AML and other types of cancer. […] If AML develops very quickly, you might suddenly have very high numbers of faulty white blood cells (leukaemia cells) in your blood. This is known as leukostasis. It can cause the blood to flow less well, and blood vessels can get blocked.

• #56 Acute Myeloid Leukemia | Conditions | UCSF Health

  https://www.ucsfhealth.org/conditions/acute-myeloid-leukemia

  Typically, symptoms of acute myeloid leukemia (AML) come on suddenly over days or weeks. […] AML makes you sick by interfering with your normal bone marrow function. Instead of producing healthy white blood cells, the bone marrow starts making abnormal ones that divide and multiply uncontrollably. These abnormal cells replace and crowd out the normal cells in your bloodstream, leading to low numbers of red blood cells, white blood cells and platelets. […] When you don’t have enough red blood cells, you can develop anemia, a condition that causes fatigue. When your platelet counts are low, you can become prone to bleeding and bruising, especially in the skin, nose and gums. […] A low white blood cell count puts you at an increased risk of infection. The infection types vary, but signs of a possible infection include: Fever, Runny nose, Cough, Chest pain, Shortness of breath, Pain when urinating, Occasional diarrhea. […] If your white blood cell count gets too low, your ability to fight off infection may be seriously compromised. This makes you vulnerable to developing potentially life-threatening conditions, such as pneumonia (a lung infection) or sepsis (a severe response to infection).

• #57 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas. […] Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #58 Disease progression of acute myeloid leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/acute-myeloid-leukemia-aml/disease-progression

  Cancer cells can spread from where they start to other parts of the body. […] Acute myeloid leukemia (AML) is often widespread when it is found. […] Understanding how a type of cancer usually grows and spreads helps your healthcare team plan your treatment and future care. […] AML cells may collect in the liver, spleen, lymph nodes, gums, skin, brain and spinal cord (called the central nervous system, or CNS), testicles, kidneys, eyes, ears, heart or other organs (in rare cases). […] Leukemia does not usually form solid tumours in the organs that it spreads to. But the buildup of abnormal cells in the organs affects them so they don’t work normally.

• #59 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas. […] Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #60 Symptoms of acute myeloid leukaemia AML | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/acute-myeloid-leukaemia-aml/symptoms

  You might notice that you’re feeling breathless more than usual or for a lot of the time. You might feel out of breath after your normal day to day activities or from climbing a short flight of stairs. This could be because you do not have enough red blood cells (anaemia). […] You might lose weight even if you haven’t changed your diet. […] You might feel pain in your bones or joints. This might be a dull ache or more of a stabbing pain. It might be worse at different times of the day. […] You might have a feeling of fullness or discomfort in your tummy (abdomen). This can happen if your liver or spleen are swollen. […] You might look paler or more 'washed out’ than normal. This could also be because you do not have enough red blood cells. […] Less common symptoms include lumps on the skin and swollen lymph nodes. Your lymph nodes (glands) might feel swollen when you touch them. You have lymph nodes in lots of places in your body. They might feel swollen in: your neck, under your armpit, in your groin. […] The symptoms of AML are often vague and can be caused by other medical conditions. The earlier an acute leukaemia is picked up, the easier it is to treat and the more likely treatment is to be successful. So go to your GP as soon as possible.

• #61 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas. […] Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #62 Symptoms of Acute Myeloid Leukaemia (AML) | Cancer Council NSW

  https://www.cancercouncil.com.au/acute-myeloid-leukaemia/symptoms/

  When leukaemia causes a build-up of abnormal white blood cells, the lymph nodes and spleen can become swollen. An enlarged spleen can cause pain or discomfort in the abdomen or back. […] These include bone or joint pain, swollen and tender gums, skin rashes, headaches, weight loss, vision problems, vomiting and chest pains.

• #63 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas. […] Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #64 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Bone or joint pain. If you have a buildup of myeloid blasts in your joints, you may have bone and joint pain. […] Myeloid blasts may build up in your liver and spleen, causing them to swell. […] If they spread to your skin, you may get lumps or spots that look like a rash. […] If they spread to your brain or spinal cord, you may have headaches, weakness, seizures, vomiting, trouble balancing, facial numbness, or blurred vision. […] If they spread to your lymph nodes, you may have swelling in any of your lymph nodes, but especially in your neck, groin, armpits, and above your collarbone.

• #65 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas. […] Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #66 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Bone or joint pain. If you have a buildup of myeloid blasts in your joints, you may have bone and joint pain. […] Myeloid blasts may build up in your liver and spleen, causing them to swell. […] If they spread to your skin, you may get lumps or spots that look like a rash. […] If they spread to your brain or spinal cord, you may have headaches, weakness, seizures, vomiting, trouble balancing, facial numbness, or blurred vision. […] If they spread to your lymph nodes, you may have swelling in any of your lymph nodes, but especially in your neck, groin, armpits, and above your collarbone.

• #67 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas. […] Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #68 Explore Acute myeloid leukaemia Symptoms And Causes Symptoms and Causes at HCG Oncology

  https://www.hcgoncology.com/types-of-cancers/acute-myeloid-leukaemia-symptoms-and-causes/

  Patients with AML also experience fatigue. Patients with AML have abnormal cells that displace the healthy cells. These patients have low levels of red blood cells, which are responsible for carrying oxygen to different tissues. Infection in these patients also imparts an excessive burden on the body. In addition, the body is also fighting against cancer, thereby consuming energy. Fatigue is also the result of emotional and psychological stress due to the disease. […] Shortness of breath may also be an acute myeloid leukemia symptom. It may be for various reasons. Anemia reduces oxygen delivery to the tissues. Lack of oxygen in the tissues may lead to shortness of breath. Infections, particularly respiratory tract infections, also result in shortness of breath. The other causes of shortness of breath include infiltration of leukemia cells in the pulmonary system and fluid accumulation in the lungs in the advanced stages of the disease.

• #69 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas. […] Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #70 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Bone or joint pain. If you have a buildup of myeloid blasts in your joints, you may have bone and joint pain. […] Myeloid blasts may build up in your liver and spleen, causing them to swell. […] If they spread to your skin, you may get lumps or spots that look like a rash. […] If they spread to your brain or spinal cord, you may have headaches, weakness, seizures, vomiting, trouble balancing, facial numbness, or blurred vision. […] If they spread to your lymph nodes, you may have swelling in any of your lymph nodes, but especially in your neck, groin, armpits, and above your collarbone.

• #71 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #72 Acute Myeloid Leukemia (AML) (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/aml.html

  Because their white blood cells can’t fight infections, kids with leukemia are more likely to get viral or bacterial infections. […] Sometimes leukemia can spread, or metastasize. If it spreads to the brain, symptoms may include headaches, seizures, balance problems, or vision problems. If it spreads to the lymph nodes in the chest, symptoms can include breathing problems and chest pain.

• #73 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #74 Quick Facts:Acute Myeloid Leukemia (AML) – Merck Manual Consumer Version

  https://www.merckmanuals.com/home/quick-facts-blood-disorders/leukemias/acute-myeloid-leukemia-aml

  Acute myeloid leukemia (AML) is a cancer of certain types of white blood cells. […] „Acute” means this type of myeloid leukemia spreads very quickly and needs immediate treatment. It’s life-threatening. […] You may be tired or pale, get infections and fever easily, and bruise or bleed easily. […] Symptoms of AML may include: Fever and heavy sweating (from infection or the leukemia), Feeling weak or tired (from anemia), Swollen gums. […] AML cells can also spread to the brain and spinal cord, causing symptoms such as: Headaches, Throwing up, Problems seeing, hearing, or balancing, Problems with your face muscles. […] Acute promyelocytic leukemia can also cause: Bleeding or blood clotting problems.

• #75 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #76 Quick Facts:Acute Myeloid Leukemia (AML) – Merck Manual Consumer Version

  https://www.merckmanuals.com/home/quick-facts-blood-disorders/leukemias/acute-myeloid-leukemia-aml

  Acute myeloid leukemia (AML) is a cancer of certain types of white blood cells. […] „Acute” means this type of myeloid leukemia spreads very quickly and needs immediate treatment. It’s life-threatening. […] You may be tired or pale, get infections and fever easily, and bruise or bleed easily. […] Symptoms of AML may include: Fever and heavy sweating (from infection or the leukemia), Feeling weak or tired (from anemia), Swollen gums. […] AML cells can also spread to the brain and spinal cord, causing symptoms such as: Headaches, Throwing up, Problems seeing, hearing, or balancing, Problems with your face muscles. […] Acute promyelocytic leukemia can also cause: Bleeding or blood clotting problems.

• #77 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #78 Quick Facts:Acute Myeloid Leukemia (AML) – Merck Manual Consumer Version

  https://www.merckmanuals.com/home/quick-facts-blood-disorders/leukemias/acute-myeloid-leukemia-aml

  Acute myeloid leukemia (AML) is a cancer of certain types of white blood cells. […] „Acute” means this type of myeloid leukemia spreads very quickly and needs immediate treatment. It’s life-threatening. […] You may be tired or pale, get infections and fever easily, and bruise or bleed easily. […] Symptoms of AML may include: Fever and heavy sweating (from infection or the leukemia), Feeling weak or tired (from anemia), Swollen gums. […] AML cells can also spread to the brain and spinal cord, causing symptoms such as: Headaches, Throwing up, Problems seeing, hearing, or balancing, Problems with your face muscles. […] Acute promyelocytic leukemia can also cause: Bleeding or blood clotting problems.

• #79 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Bone or joint pain. If you have a buildup of myeloid blasts in your joints, you may have bone and joint pain. […] Myeloid blasts may build up in your liver and spleen, causing them to swell. […] If they spread to your skin, you may get lumps or spots that look like a rash. […] If they spread to your brain or spinal cord, you may have headaches, weakness, seizures, vomiting, trouble balancing, facial numbness, or blurred vision. […] If they spread to your lymph nodes, you may have swelling in any of your lymph nodes, but especially in your neck, groin, armpits, and above your collarbone.

• #80 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Bone or joint pain. If you have a buildup of myeloid blasts in your joints, you may have bone and joint pain. […] Myeloid blasts may build up in your liver and spleen, causing them to swell. […] If they spread to your skin, you may get lumps or spots that look like a rash. […] If they spread to your brain or spinal cord, you may have headaches, weakness, seizures, vomiting, trouble balancing, facial numbness, or blurred vision. […] If they spread to your lymph nodes, you may have swelling in any of your lymph nodes, but especially in your neck, groin, armpits, and above your collarbone.

• #81 Acute Myeloid Leukemia (AML): Symptoms | UMass Memorial Health

  https://www.ummhealth.org/health-library/acute-myeloid-leukemia-aml-symptoms

  Symptoms of AML can be different in each person. The most common symptoms include: Bleeding that’s hard to stop. Easy bruising. Fever. Frequent infections or infections that keep coming back. Feeling weak. Feeling very tired (fatigue). Pale skin. Shortness of breath. Chest pain. Dizziness. Headaches. Blurred vision. Aches in back, bones, and joints. Swollen or bleeding gums. Swollen lymph nodes, liver, or spleen. Loss of appetite. Unplanned weight loss. Rashes of tiny flat red or purple spots under the skin (caused by bleeding). Sores or wounds that don’t heal. Night sweats. Heavy periods, more frequent periods, or periods that last longer than normal. […] Many of these symptoms can be caused by other, more common health problems. In fact, most of them are more likely to be caused by something else. Still, it’s important to see a doctor if you have these symptoms. Only a doctor can tell if you have AML, another type of cancer, or some other medical problem that needs to be treated.

• #82 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #83 Acute Myeloid Leukemia: Symptoms and More

  https://resources.healthgrades.com/right-care/leukemia/acute-myeloid-leukemia-symptoms

  Symptoms include those of: stroke: slurred speech, loss of sensation and movement on one side of the body; deep vein thrombosis: swelling, redness or discoloration of the skin, increased warmth to that area of skin; pulmonary embolism: chest pain, shortness of breath. […] Symptoms in other areas of the body can include: pain in bones and joints; swelling in the abdomen from an enlarged spleen or liver; lumps or spots that look like rashes on the skin. […] This pressure can cause: seizures; stroke; pain; weakness; nausea and vomiting; headaches; balance issues; vision changes; numbness of the face. […] Symptoms occur because atypical blood cells created in increasing numbers do not function like typical blood cells. The most common symptoms are weakness and fatigue, bleeding issues, shortness of breath, and fever.

• #84 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #85 Acute myeloid leukaemia – Symptoms, diagnosis and treatment | BMJ Best Practice

  https://bestpractice.bmj.com/topics/en-gb/274

  Acute myeloid leukaemia (AML) is a life-threatening haematological malignancy that predominantly occurs in older adults. […] Characteristically, abnormal myeloid blasts are present in the bone marrow (and in some cases the peripheral blood and extramedullary tissue) and normal haematopoiesis is reduced. […] The APL subtype of AML is characterised by a distinctive cytomorphology (hypergranular promyelocytes with bilobed nuclei and bundles of Auer rods), a tendency for coagulopathy (due to thrombocytopenia and disseminated intravascular coagulation), and a specific t(15;17)(q22;q12) cytogenetic abnormality resulting in the PML::RARA fusion gene. […] Key diagnostic factors include pallor and ecchymoses or petechiae. […] Other diagnostic factors include fatigue, dizziness, palpitations, dyspnoea, fever and infections, lymphadenopathy, hepatosplenomegaly, mucosal bleeding, skin and/or testicular mass, skin infiltration, gingival enlargement, bone pain, skin chloromas, abdominal pain, and neurological symptoms (e.g., headache, confusion).

• #86 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another. […] A shortage of blood platelets is called thrombocytopenia. This can lead to: Bruises (or small red or purple spots) on the skin, Excess bleeding, Frequent or severe nosebleeds, Bleeding gums, Heavy periods (menstrual bleeding) in women. […] The cancer cells in AML (called blasts) are bigger than normal blood cells and have more trouble traveling through tiny blood vessels. If the blast count gets very high, these cells can clog up blood vessels and make it hard for normal red blood cells (and oxygen) to get to tissues. This is called leukostasis.

• #87 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Symptoms of low white blood cell counts include: Infections that don’t seem to go away, Back-to-back infections, Fever. […] Symptoms of low platelet counts include: Bruises on your skin, including small red or purple spots called petechiae, Bleeding from your gums, Frequent or severe nosebleeds, Bleeding excessively, Heavy bleeding during your menstrual period. […] If you have a type of AML called acute promyelocytic leukemia (APL), you may have problems with bleeding or blood clotting. […] When you have AML, your bone marrow makes abnormal cells called myeloid blasts. These cells are bigger than normal white blood cells, so they have trouble moving through your smaller blood vessels. If you have high levels of these myeloid blasts, they may block the flow in small blood vessels. This may make it hard for your red blood cells to deliver oxygen to all your tissues. This is called leukostasis, and it’s a rare symptom of AML.

• #88 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  If you have AML and you get any symptoms of an infection (sometimes this might only be a high temperature), you should get urgent medical help, because there is a risk of developing life-threatening sepsis. […] Having a low white blood cell count can cause: repeated infections […] infections that are hard to get rid of […] fever (high temperature) […] infections such as pneumonia, urinary tract infections (UTIs) or gastroenteritis. […] Some people with AML have bone pain or joint pain caused by the build-up of leukaemia cells in these areas. […] We dont fully understand the link between AML and weight loss, but losing weight without changing your diet is a symptom of AML and other types of cancer. […] If AML develops very quickly, you might suddenly have very high numbers of faulty white blood cells (leukaemia cells) in your blood. This is known as leukostasis. It can cause the blood to flow less well, and blood vessels can get blocked.

• #89 AML Signs and Symptoms – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/aml-signs-and-symptoms

  The symptoms of AML are largely related to a deficiency in healthy blood cells. Anemia: When your body doesn’t have enough healthy red blood cells, it cannot transfer adequate amounts of oxygen, leading to symptoms such as a pale complexion, fatigue, weakness, and shortness of breath. Bleeding: A low platelet count leads to easy bruising and excessive bleeding. Weakened Immune System: A lack of white blood cells compromises your immune system, making you more susceptible to infections and slower to recover from them. […] As AML progresses, you may experience additional symptoms due to the high number of leukemia cells: Leukostasis: This occurs when large leukemia cells clog blood vessels, potentially causing symptoms similar to a stroke, such as headache, weakness on one side of the body, slurred speech, confusion, and sleepiness. Bleeding and Clotting Issues: People with acute promyelocytic leukemia (APL), a subtype of AML, often experience severe bleeding and clotting problems.

• #90 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #91 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #92 Acute Myeloid Leukemia (AML) Clinical Presentation: History, Physical Examination

  https://emedicine.medscape.com/article/197802-clinical

  Patients with markedly elevated WBC counts (100,000 cells/L) can present with symptoms of leukostasis (ie, respiratory distress and altered mental status). Leukostasis is a medical emergency that calls for immediate intervention. Patients with a high leukemic cell burden may present with bone pain caused by increased pressure in the bone marrow.

• #93 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #94 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #95 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #96 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #97 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #98 Acute myeloid leukaemia (AML) symptoms | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/acute-myeloid-leukaemia/aml-symptoms-diagnosis/symptoms/

  This is a medical emergency that needs to be treated straight away. […] Some of the symptoms are similar to those seen with stroke (neurological symptoms) and include: headache […] breathing problems […] loss of muscle control or seizures […] slurred speech […] vision changes […] confusion […] sleepiness […] vomiting. […] Leukaemia cells can build up in organs like the liver and spleen, making them larger. You might notice this as a fullness or swelling of the tummy area. […] Sometimes, leukaemia cells can collect in lymph nodes, making them swollen. […] A chloroma is rare symptom of AML that happens if leukaemia cells collect together and form a lump (nodule).

• #99 Acute Myeloid Leukemia (AML) Clinical Presentation: History, Physical Examination

  https://emedicine.medscape.com/article/197802-clinical

  Patients with markedly elevated WBC counts (100,000 cells/L) can present with symptoms of leukostasis (ie, respiratory distress and altered mental status). Leukostasis is a medical emergency that calls for immediate intervention. Patients with a high leukemic cell burden may present with bone pain caused by increased pressure in the bone marrow.

• #100 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://www.webmd.com/cancer/lymphoma/acute-myeloid-leukemia-symptoms-treatments

  Symptoms of low white blood cell counts include: Infections that don’t seem to go away, Back-to-back infections, Fever. […] Symptoms of low platelet counts include: Bruises on your skin, including small red or purple spots called petechiae, Bleeding from your gums, Frequent or severe nosebleeds, Bleeding excessively, Heavy bleeding during your menstrual period. […] If you have a type of AML called acute promyelocytic leukemia (APL), you may have problems with bleeding or blood clotting. […] When you have AML, your bone marrow makes abnormal cells called myeloid blasts. These cells are bigger than normal white blood cells, so they have trouble moving through your smaller blood vessels. If you have high levels of these myeloid blasts, they may block the flow in small blood vessels. This may make it hard for your red blood cells to deliver oxygen to all your tissues. This is called leukostasis, and it’s a rare symptom of AML.

• #101 Acute Myeloid Leukemia – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507875/

  Common physical examination findings in AML include pallor, bruising, and hepatosplenomegaly, while lymphadenopathy is rare. Myeloid sarcoma, a myeloid equivalent, may present as thickened, hyperpigmented, coarse skin lesions. Disseminated intravascular coagulation (DIC), characterized clinically by oral mucosal hemorrhages, purpura, extremity petechiae, and bleeding from intravenous line sites, is common in AML. […] AML should be suspected in individuals presenting with rapid (within days or a few weeks) unexplained cytopenias (decreased leukocytes, hemoglobin, or platelets), circulating blast cells in peripheral blood, easy bruising or bleeding, or recurrent infections. In some cases, patients may present with renal failure due to auto-tumor lysis syndrome (auto-TLS), which, even in the absence of prior chemotherapy, is considered an oncologic emergency.

• #102 Acute Myeloid Leukemia – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507875/

  Common physical examination findings in AML include pallor, bruising, and hepatosplenomegaly, while lymphadenopathy is rare. Myeloid sarcoma, a myeloid equivalent, may present as thickened, hyperpigmented, coarse skin lesions. Disseminated intravascular coagulation (DIC), characterized clinically by oral mucosal hemorrhages, purpura, extremity petechiae, and bleeding from intravenous line sites, is common in AML. […] AML should be suspected in individuals presenting with rapid (within days or a few weeks) unexplained cytopenias (decreased leukocytes, hemoglobin, or platelets), circulating blast cells in peripheral blood, easy bruising or bleeding, or recurrent infections. In some cases, patients may present with renal failure due to auto-tumor lysis syndrome (auto-TLS), which, even in the absence of prior chemotherapy, is considered an oncologic emergency.

• #103 Acute myeloid leukemia – Wikipedia

  https://en.wikipedia.org/wiki/Acute_myeloid_leukemia

  Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection. […] As an acute leukemia, AML progresses rapidly, and is typically fatal within weeks or months if left untreated. […] Most signs and symptoms of AML are caused by the crowding out in bone marrow of space for normal blood cells to develop. A lack of normal white blood cell production makes people more susceptible to infections. A low red blood cell count (anemia) can cause fatigue, paleness, shortness of breath and palpitations. A lack of platelets can lead to easy bruising, bleeding from the nose (epistaxis), small blood vessels on the skin (petechiae) or gums, or bleeding with minor trauma. Other symptoms may include fever, fatigue worse than what can be attributed to anemia alone, weight loss and loss of appetite.

• #104 Acute myelogenous leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/acute-myelogenous-leukemia/symptoms-causes/syc-20369109

  Symptoms of acute myelogenous leukemia may include: Fever. Pain. Common places for pain include the bones, back and stomach. Feeling very tired. Paleness or change in skin color. Frequent infections. Easy bruising. Bleeding with no clear cause, such as in the nose or gums. Shortness of breath. […] Acute myelogenous leukemia symptoms are like those of many more-common conditions, such as infections. The healthcare professional may check for those causes first. […] The changes that lead to acute myelogenous leukemia are thought to happen in cells called myeloid cells. […] The DNA changes cause the myeloid cells to make a lot of immature white blood cells, called myeloblasts. The myeloblasts don’t work right. They can build up in the bone marrow. They can crowd out healthy blood cells. Without enough healthy blood cells, there might be low oxygen levels in the blood, easy bruising and bleeding, and frequent infections.

• #105 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  Acute myeloid leukemia (AML) begins in the bone marrow and initially may cause flu-like symptoms. As abnormal white blood cells (cancerous cells) build up, these symptoms can change or worsen. As AML is an aggressive form of cancer, it can progress rapidly. […] As AML progresses towards the final stages, symptoms may become more severe. Body functions may slow down, and complications may arise. Cancerous cells multiply, which may prevent the bone marrow from making new blood cells. This can cause: Anemia, Bleeding, An increased risk of infection. […] Patients may also experience swelling and pain in the bones and joints due to the bone marrow becoming crowded with cancerous cells. Some patients may experience shortness of breath or breathing difficulties. Towards the final days, breathing may become irregular or louder.

• #106 Are there any early signs of acute myeloid leukemia?

  https://www.medicalnewstoday.com/articles/early-signs-of-aml-leukemia

  Without treatment, these symptoms usually develop and worsen rapidly as the number of leukemia cells increase. […] Health experts describe AML as an acute type of leukemia. This term means that it is aggressive and has a rapid onset and progression. A person may not show any symptoms during its early stage but will begin to experience symptoms as the condition advances. […] Typically, symptoms of AML may appear 4-6 weeks before diagnosis. As the condition becomes more advanced, the varying symptoms will become more noticeable. […] AML is an aggressive form of leukemia that can cause a range of symptoms early in the disease process. […] However, these symptoms, such as fever, fatigue, and bone and joint pain, are general, and a person could mistake them for another condition, such as the flu. […] There are currently no screening tests to detect AML early. But it is vital for a person to reach out to a primary care doctor if they are experiencing persistent symptoms, which may indicate the presence of the disease.

• #107 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  Acute myeloid leukemia (AML) begins in the bone marrow and initially may cause flu-like symptoms. As abnormal white blood cells (cancerous cells) build up, these symptoms can change or worsen. As AML is an aggressive form of cancer, it can progress rapidly. […] As AML progresses towards the final stages, symptoms may become more severe. Body functions may slow down, and complications may arise. Cancerous cells multiply, which may prevent the bone marrow from making new blood cells. This can cause: Anemia, Bleeding, An increased risk of infection. […] Patients may also experience swelling and pain in the bones and joints due to the bone marrow becoming crowded with cancerous cells. Some patients may experience shortness of breath or breathing difficulties. Towards the final days, breathing may become irregular or louder.

• #108 Final Stages of Acute Myeloid Leukemia: Symptoms & Support

  https://www.healthline.com/health/final-stages-of-acute-myeloid-leukemia

  Acute myeloid leukemia (AML) is a progressive type of cancer that affects your bone marrow and blood cells. […] Early detection and treatment are important to help increase the chances of survival from this cancer. See a doctor right away if you notice any possible early symptoms. These include: recurring infections, chronic fever, unusual bleeding. […] Symptoms of the final stages of AML are similar to end-stage symptoms of all types of leukemia. These may include: cool, dry skin, slow or labored breathing, blurry vision, decreased urination or incontinence, restlessness or involuntary muscle movements, decreased movements or weakness, loss of appetite and decreased fluid intake, increased drowsiness and sleepiness, changes in heart rate, signs of bleeding, such as under the skin (petechiae) or from the nose, pain, hallucinations, confusion, loss of consciousness.

• #109 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  Acute myeloid leukemia (AML) begins in the bone marrow and initially may cause flu-like symptoms. As abnormal white blood cells (cancerous cells) build up, these symptoms can change or worsen. As AML is an aggressive form of cancer, it can progress rapidly. […] As AML progresses towards the final stages, symptoms may become more severe. Body functions may slow down, and complications may arise. Cancerous cells multiply, which may prevent the bone marrow from making new blood cells. This can cause: Anemia, Bleeding, An increased risk of infection. […] Patients may also experience swelling and pain in the bones and joints due to the bone marrow becoming crowded with cancerous cells. Some patients may experience shortness of breath or breathing difficulties. Towards the final days, breathing may become irregular or louder.

• #110 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  Acute myeloid leukemia (AML) begins in the bone marrow and initially may cause flu-like symptoms. As abnormal white blood cells (cancerous cells) build up, these symptoms can change or worsen. As AML is an aggressive form of cancer, it can progress rapidly. […] As AML progresses towards the final stages, symptoms may become more severe. Body functions may slow down, and complications may arise. Cancerous cells multiply, which may prevent the bone marrow from making new blood cells. This can cause: Anemia, Bleeding, An increased risk of infection. […] Patients may also experience swelling and pain in the bones and joints due to the bone marrow becoming crowded with cancerous cells. Some patients may experience shortness of breath or breathing difficulties. Towards the final days, breathing may become irregular or louder.

• #111 Acute myeloid leukaemia | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/cancer/cancer-types-in-adults/acute-myeloid-leukaemia/

  The symptoms of acute myeloid leukaemia (AML) usually develop over a few weeks, becoming more severe as the number of immature white blood cells (blast cells) in your blood increases. […] Symptoms can include: pale skin, tiredness, breathlessness, a high temperature (fever), excessive sweating, weight loss, frequent infections, unusual and frequent bleeding, such as bleeding gums or nosebleeds, easily bruised skin, flat red or purple spots on the skin (petechiae), bone and joint pain, a feeling of fullness or discomfort in your tummy (abdomen), caused by swelling of the liver or spleen. […] In more advanced cases, AML can make you extremely vulnerable to life-threatening infections or serious internal bleeding. […] If you have AML, you’ll bleed and bruise more easily due to the low levels of platelets (clot-forming cells) in your blood. Bleeding may also be excessive. […] People with advanced AML are more vulnerable to excessive bleeding inside their body, which is the second most common cause of death in people with the condition.

• #112 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  Acute myeloid leukemia (AML) begins in the bone marrow and initially may cause flu-like symptoms. As abnormal white blood cells (cancerous cells) build up, these symptoms can change or worsen. As AML is an aggressive form of cancer, it can progress rapidly. […] As AML progresses towards the final stages, symptoms may become more severe. Body functions may slow down, and complications may arise. Cancerous cells multiply, which may prevent the bone marrow from making new blood cells. This can cause: Anemia, Bleeding, An increased risk of infection. […] Patients may also experience swelling and pain in the bones and joints due to the bone marrow becoming crowded with cancerous cells. Some patients may experience shortness of breath or breathing difficulties. Towards the final days, breathing may become irregular or louder.

• #113 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  Acute myeloid leukemia (AML) begins in the bone marrow and initially may cause flu-like symptoms. As abnormal white blood cells (cancerous cells) build up, these symptoms can change or worsen. As AML is an aggressive form of cancer, it can progress rapidly. […] As AML progresses towards the final stages, symptoms may become more severe. Body functions may slow down, and complications may arise. Cancerous cells multiply, which may prevent the bone marrow from making new blood cells. This can cause: Anemia, Bleeding, An increased risk of infection. […] Patients may also experience swelling and pain in the bones and joints due to the bone marrow becoming crowded with cancerous cells. Some patients may experience shortness of breath or breathing difficulties. Towards the final days, breathing may become irregular or louder.

• #114 Disease progression of acute myeloid leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/acute-myeloid-leukemia-aml/disease-progression

  Cancer cells can spread from where they start to other parts of the body. […] Acute myeloid leukemia (AML) is often widespread when it is found. […] Understanding how a type of cancer usually grows and spreads helps your healthcare team plan your treatment and future care. […] AML cells may collect in the liver, spleen, lymph nodes, gums, skin, brain and spinal cord (called the central nervous system, or CNS), testicles, kidneys, eyes, ears, heart or other organs (in rare cases). […] Leukemia does not usually form solid tumours in the organs that it spreads to. But the buildup of abnormal cells in the organs affects them so they don’t work normally.

• #115 Acute Myelogenous Leukemia (AML) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/acute-myelogenous-leukemia-aml

  Leukemia cells can collect in the kidneys, liver, and spleen, causing enlargement of these organs which can cause pain in the abdomen. This pain may lead to loss of appetite and weight loss. […] Lymph nodes filter the blood. Leukemia cells often collect in the nodes, causing swelling. Swelling occurs in lymph nodes in the neck, under the arms, in the groin, and chest. […] In leukemia, cells can clump together in the thymus a gland under the breastbone and around the throat. This mass of cells can cause difficulty breathing. Any wheezing, coughing, and/or labored or painful breathing requires immediate medical attention.

• #116 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #117 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #118 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #119 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #120 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #121 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #122 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #123 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #124 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #125 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #126 Final Stages of Acute Myeloid Leukemia: Symptoms & Support

  https://www.healthline.com/health/final-stages-of-acute-myeloid-leukemia

  Acute myeloid leukemia (AML) is a progressive type of cancer that affects your bone marrow and blood cells. […] Early detection and treatment are important to help increase the chances of survival from this cancer. See a doctor right away if you notice any possible early symptoms. These include: recurring infections, chronic fever, unusual bleeding. […] Symptoms of the final stages of AML are similar to end-stage symptoms of all types of leukemia. These may include: cool, dry skin, slow or labored breathing, blurry vision, decreased urination or incontinence, restlessness or involuntary muscle movements, decreased movements or weakness, loss of appetite and decreased fluid intake, increased drowsiness and sleepiness, changes in heart rate, signs of bleeding, such as under the skin (petechiae) or from the nose, pain, hallucinations, confusion, loss of consciousness.

• #127 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #128 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #129 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #130 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #131 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  Acute myeloid leukemia (AML) begins in the bone marrow and initially may cause flu-like symptoms. As abnormal white blood cells (cancerous cells) build up, these symptoms can change or worsen. As AML is an aggressive form of cancer, it can progress rapidly. […] As AML progresses towards the final stages, symptoms may become more severe. Body functions may slow down, and complications may arise. Cancerous cells multiply, which may prevent the bone marrow from making new blood cells. This can cause: Anemia, Bleeding, An increased risk of infection. […] Patients may also experience swelling and pain in the bones and joints due to the bone marrow becoming crowded with cancerous cells. Some patients may experience shortness of breath or breathing difficulties. Towards the final days, breathing may become irregular or louder.

• #132 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #133 Final Stages of Acute Myeloid Leukemia: Symptoms & Support

  https://www.healthline.com/health/final-stages-of-acute-myeloid-leukemia

  Acute myeloid leukemia (AML) is a progressive type of cancer that affects your bone marrow and blood cells. […] Early detection and treatment are important to help increase the chances of survival from this cancer. See a doctor right away if you notice any possible early symptoms. These include: recurring infections, chronic fever, unusual bleeding. […] Symptoms of the final stages of AML are similar to end-stage symptoms of all types of leukemia. These may include: cool, dry skin, slow or labored breathing, blurry vision, decreased urination or incontinence, restlessness or involuntary muscle movements, decreased movements or weakness, loss of appetite and decreased fluid intake, increased drowsiness and sleepiness, changes in heart rate, signs of bleeding, such as under the skin (petechiae) or from the nose, pain, hallucinations, confusion, loss of consciousness.

• #134 Final Stages of Acute Myeloid Leukemia: Symptoms & Support

  https://www.healthline.com/health/final-stages-of-acute-myeloid-leukemia

  Acute myeloid leukemia (AML) is a progressive type of cancer that affects your bone marrow and blood cells. […] Early detection and treatment are important to help increase the chances of survival from this cancer. See a doctor right away if you notice any possible early symptoms. These include: recurring infections, chronic fever, unusual bleeding. […] Symptoms of the final stages of AML are similar to end-stage symptoms of all types of leukemia. These may include: cool, dry skin, slow or labored breathing, blurry vision, decreased urination or incontinence, restlessness or involuntary muscle movements, decreased movements or weakness, loss of appetite and decreased fluid intake, increased drowsiness and sleepiness, changes in heart rate, signs of bleeding, such as under the skin (petechiae) or from the nose, pain, hallucinations, confusion, loss of consciousness.

• #135 Final Stages of Acute Myeloid Leukemia: Symptoms & Support

  https://www.healthline.com/health/final-stages-of-acute-myeloid-leukemia

  Acute myeloid leukemia (AML) is a progressive type of cancer that affects your bone marrow and blood cells. […] Early detection and treatment are important to help increase the chances of survival from this cancer. See a doctor right away if you notice any possible early symptoms. These include: recurring infections, chronic fever, unusual bleeding. […] Symptoms of the final stages of AML are similar to end-stage symptoms of all types of leukemia. These may include: cool, dry skin, slow or labored breathing, blurry vision, decreased urination or incontinence, restlessness or involuntary muscle movements, decreased movements or weakness, loss of appetite and decreased fluid intake, increased drowsiness and sleepiness, changes in heart rate, signs of bleeding, such as under the skin (petechiae) or from the nose, pain, hallucinations, confusion, loss of consciousness.

• #136 Final Stages of Acute Myeloid Leukemia: Symptoms & Support

  https://www.healthline.com/health/final-stages-of-acute-myeloid-leukemia

  Acute myeloid leukemia (AML) is a progressive type of cancer that affects your bone marrow and blood cells. […] Early detection and treatment are important to help increase the chances of survival from this cancer. See a doctor right away if you notice any possible early symptoms. These include: recurring infections, chronic fever, unusual bleeding. […] Symptoms of the final stages of AML are similar to end-stage symptoms of all types of leukemia. These may include: cool, dry skin, slow or labored breathing, blurry vision, decreased urination or incontinence, restlessness or involuntary muscle movements, decreased movements or weakness, loss of appetite and decreased fluid intake, increased drowsiness and sleepiness, changes in heart rate, signs of bleeding, such as under the skin (petechiae) or from the nose, pain, hallucinations, confusion, loss of consciousness.

• #137 Final Stages of Acute Myeloid Leukemia: Symptoms & Support

  https://www.healthline.com/health/final-stages-of-acute-myeloid-leukemia

  Acute myeloid leukemia (AML) is a progressive type of cancer that affects your bone marrow and blood cells. […] Early detection and treatment are important to help increase the chances of survival from this cancer. See a doctor right away if you notice any possible early symptoms. These include: recurring infections, chronic fever, unusual bleeding. […] Symptoms of the final stages of AML are similar to end-stage symptoms of all types of leukemia. These may include: cool, dry skin, slow or labored breathing, blurry vision, decreased urination or incontinence, restlessness or involuntary muscle movements, decreased movements or weakness, loss of appetite and decreased fluid intake, increased drowsiness and sleepiness, changes in heart rate, signs of bleeding, such as under the skin (petechiae) or from the nose, pain, hallucinations, confusion, loss of consciousness.

• #138 Final Stages of Acute Myeloid Leukemia: Symptoms & Support

  https://www.healthline.com/health/final-stages-of-acute-myeloid-leukemia

  Acute myeloid leukemia (AML) is a progressive type of cancer that affects your bone marrow and blood cells. […] Early detection and treatment are important to help increase the chances of survival from this cancer. See a doctor right away if you notice any possible early symptoms. These include: recurring infections, chronic fever, unusual bleeding. […] Symptoms of the final stages of AML are similar to end-stage symptoms of all types of leukemia. These may include: cool, dry skin, slow or labored breathing, blurry vision, decreased urination or incontinence, restlessness or involuntary muscle movements, decreased movements or weakness, loss of appetite and decreased fluid intake, increased drowsiness and sleepiness, changes in heart rate, signs of bleeding, such as under the skin (petechiae) or from the nose, pain, hallucinations, confusion, loss of consciousness.

• #139 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #140

  https://www.nhs.uk/conditions/acute-myeloid-leukaemia/

  The symptoms of AML usually develop over a few weeks and become worse over time. […] Symptoms can include: […] looking pale or „washed out” […] feeling tired or weak […] breathlessness […] frequent infections […] unusual and frequent bruising or bleeding, such as bleeding gums or nosebleeds […] losing weight without trying to. […] Treatment for AML needs to begin as soon as possible, as it can develop quickly.

• #141 Final Stages of Acute Myeloid Leukemia: Symptoms & Support

  https://www.healthline.com/health/final-stages-of-acute-myeloid-leukemia

  While AML can progress rapidly, an early diagnosis followed by aggressive treatment may help you live as long as possible. […] Despite treatment, there are certain factors that can increase the risk of reaching the end stages of AML. These include older age, cancer subtype, and whether the cancer has spread to vital organs.

• #142 Symptoms of acute myeloid leukaemia AML | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/acute-myeloid-leukaemia-aml/symptoms

  You might notice that you’re feeling breathless more than usual or for a lot of the time. You might feel out of breath after your normal day to day activities or from climbing a short flight of stairs. This could be because you do not have enough red blood cells (anaemia). […] You might lose weight even if you haven’t changed your diet. […] You might feel pain in your bones or joints. This might be a dull ache or more of a stabbing pain. It might be worse at different times of the day. […] You might have a feeling of fullness or discomfort in your tummy (abdomen). This can happen if your liver or spleen are swollen. […] You might look paler or more 'washed out’ than normal. This could also be because you do not have enough red blood cells. […] Less common symptoms include lumps on the skin and swollen lymph nodes. Your lymph nodes (glands) might feel swollen when you touch them. You have lymph nodes in lots of places in your body. They might feel swollen in: your neck, under your armpit, in your groin. […] The symptoms of AML are often vague and can be caused by other medical conditions. The earlier an acute leukaemia is picked up, the easier it is to treat and the more likely treatment is to be successful. So go to your GP as soon as possible.

• #143 Are there any early signs of acute myeloid leukemia?

  https://www.medicalnewstoday.com/articles/early-signs-of-aml-leukemia

  Without treatment, these symptoms usually develop and worsen rapidly as the number of leukemia cells increase. […] Health experts describe AML as an acute type of leukemia. This term means that it is aggressive and has a rapid onset and progression. A person may not show any symptoms during its early stage but will begin to experience symptoms as the condition advances. […] Typically, symptoms of AML may appear 4-6 weeks before diagnosis. As the condition becomes more advanced, the varying symptoms will become more noticeable. […] AML is an aggressive form of leukemia that can cause a range of symptoms early in the disease process. […] However, these symptoms, such as fever, fatigue, and bone and joint pain, are general, and a person could mistake them for another condition, such as the flu. […] There are currently no screening tests to detect AML early. But it is vital for a person to reach out to a primary care doctor if they are experiencing persistent symptoms, which may indicate the presence of the disease.

• #144 Are there any early signs of acute myeloid leukemia?

  https://www.medicalnewstoday.com/articles/early-signs-of-aml-leukemia

  Without treatment, these symptoms usually develop and worsen rapidly as the number of leukemia cells increase. […] Health experts describe AML as an acute type of leukemia. This term means that it is aggressive and has a rapid onset and progression. A person may not show any symptoms during its early stage but will begin to experience symptoms as the condition advances. […] Typically, symptoms of AML may appear 4-6 weeks before diagnosis. As the condition becomes more advanced, the varying symptoms will become more noticeable. […] AML is an aggressive form of leukemia that can cause a range of symptoms early in the disease process. […] However, these symptoms, such as fever, fatigue, and bone and joint pain, are general, and a person could mistake them for another condition, such as the flu. […] There are currently no screening tests to detect AML early. But it is vital for a person to reach out to a primary care doctor if they are experiencing persistent symptoms, which may indicate the presence of the disease.

• #145 Are there any early signs of acute myeloid leukemia?

  https://www.medicalnewstoday.com/articles/early-signs-of-aml-leukemia

  Without treatment, these symptoms usually develop and worsen rapidly as the number of leukemia cells increase. […] Health experts describe AML as an acute type of leukemia. This term means that it is aggressive and has a rapid onset and progression. A person may not show any symptoms during its early stage but will begin to experience symptoms as the condition advances. […] Typically, symptoms of AML may appear 4-6 weeks before diagnosis. As the condition becomes more advanced, the varying symptoms will become more noticeable. […] AML is an aggressive form of leukemia that can cause a range of symptoms early in the disease process. […] However, these symptoms, such as fever, fatigue, and bone and joint pain, are general, and a person could mistake them for another condition, such as the flu. […] There are currently no screening tests to detect AML early. But it is vital for a person to reach out to a primary care doctor if they are experiencing persistent symptoms, which may indicate the presence of the disease.

• #146 Symptoms of acute myeloid leukaemia AML | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/acute-myeloid-leukaemia-aml/symptoms

  You might notice that you’re feeling breathless more than usual or for a lot of the time. You might feel out of breath after your normal day to day activities or from climbing a short flight of stairs. This could be because you do not have enough red blood cells (anaemia). […] You might lose weight even if you haven’t changed your diet. […] You might feel pain in your bones or joints. This might be a dull ache or more of a stabbing pain. It might be worse at different times of the day. […] You might have a feeling of fullness or discomfort in your tummy (abdomen). This can happen if your liver or spleen are swollen. […] You might look paler or more 'washed out’ than normal. This could also be because you do not have enough red blood cells. […] Less common symptoms include lumps on the skin and swollen lymph nodes. Your lymph nodes (glands) might feel swollen when you touch them. You have lymph nodes in lots of places in your body. They might feel swollen in: your neck, under your armpit, in your groin. […] The symptoms of AML are often vague and can be caused by other medical conditions. The earlier an acute leukaemia is picked up, the easier it is to treat and the more likely treatment is to be successful. So go to your GP as soon as possible.

• #147 Acute myeloid leukemia – adult Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/diseases-conditions/acute-myeloid-leukemia-adult

  Acute myeloid leukemia (AML) is cancer that starts inside bone marrow. This is the soft tissue in the center of bones that helps form all blood cells. The cancer grows from cells that would normally turn into white blood cells. […] Acute means the disease grows quickly and usually has an aggressive course. […] Symptoms of AML are mainly due to the effects on blood elements. Symptoms of AML may include any of the following: Bleeding from the nose, Bleeding and swelling (rare) in the gums, Bruising, Bone pain or tenderness, Fever and fatigue, Heavy menstrual periods, Pale skin, Shortness of breath (gets worse with exercise), Weight loss. […] When a bone marrow biopsy shows no evidence of AML, you are said to be in remission. How well you do depends on your overall health and the genetic subtype of the AML cells. […] With treatment, younger people with AML tend to do better than those who develop the disease at an older age. The 5-year survival rate is much lower in older adults than in younger people. […] If the cancer does not come back (relapse) within 5 years of the diagnosis, you are likely cured.

• #148 Acute Myeloid Leukemia (AML) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/acute-myeloid-leukemia-aml

  Symptoms include fatigue, weakness, weight loss, loss of appetite, fever, shortness of breath. […] In people with AML, symptoms usually develop and progress rapidly over the course of a few weeks. […] Because red blood cells carry oxygen to tissues and organs around the body, people with low levels of red blood cells may have shortness of breath and feel tired. […] Symptoms may include: Feeling tired/weakness, Fever, Shortness of breath, Easy bruising and/or bleeding, Frequent nosebleeds and/or bleeding gums, Heavy menstrual flow in women, Unintentional weight loss, Pale skin, Nosebleeds and/or bleeding gums, Frequent infections, Headache, Bone and joint pain, Tiny red spots on skin (caused by bleeding under the skin), Small bumps, nodules, and/or rash on skin, Vision problems, Abdominal swelling. […] The five-year survival rate for adults with AML in the U.S. is 29.5%. For children and adolescents aged 19 or younger, the five-year survival rate is 66%. APL has a more favorable prognosis than AML and, in the majority of cases, can be cured.

• #149 Acute Myeloid Leukemia (AML) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/acute-myeloid-leukemia-aml

  Symptoms include fatigue, weakness, weight loss, loss of appetite, fever, shortness of breath. […] In people with AML, symptoms usually develop and progress rapidly over the course of a few weeks. […] Because red blood cells carry oxygen to tissues and organs around the body, people with low levels of red blood cells may have shortness of breath and feel tired. […] Symptoms may include: Feeling tired/weakness, Fever, Shortness of breath, Easy bruising and/or bleeding, Frequent nosebleeds and/or bleeding gums, Heavy menstrual flow in women, Unintentional weight loss, Pale skin, Nosebleeds and/or bleeding gums, Frequent infections, Headache, Bone and joint pain, Tiny red spots on skin (caused by bleeding under the skin), Small bumps, nodules, and/or rash on skin, Vision problems, Abdominal swelling. […] The five-year survival rate for adults with AML in the U.S. is 29.5%. For children and adolescents aged 19 or younger, the five-year survival rate is 66%. APL has a more favorable prognosis than AML and, in the majority of cases, can be cured.

• #150 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://my.clevelandclinic.org/health/diseases/6212-acute-myeloid-leukemia-aml

  Currently, allogeneic stem cell transplantation is the only way to cure acute myeloid leukemia. Depending on your situation, your provider may recommend stem cell transplantation as your first AML treatment or if you have AML that comes back within 12 months. Unfortunately, not everyone may be a candidate for stem cell transplantation. […] Overall, an estimated 50% to 80% of people with acute myeloid leukemia achieve complete remission after treatment. Complete remission happens more often in children and people under age 60. Remission may last for months or years.

• #151 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://my.clevelandclinic.org/health/diseases/6212-acute-myeloid-leukemia-aml

  Currently, allogeneic stem cell transplantation is the only way to cure acute myeloid leukemia. Depending on your situation, your provider may recommend stem cell transplantation as your first AML treatment or if you have AML that comes back within 12 months. Unfortunately, not everyone may be a candidate for stem cell transplantation. […] Overall, an estimated 50% to 80% of people with acute myeloid leukemia achieve complete remission after treatment. Complete remission happens more often in children and people under age 60. Remission may last for months or years.

• #152 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://my.clevelandclinic.org/health/diseases/6212-acute-myeloid-leukemia-aml

  Currently, allogeneic stem cell transplantation is the only way to cure acute myeloid leukemia. Depending on your situation, your provider may recommend stem cell transplantation as your first AML treatment or if you have AML that comes back within 12 months. Unfortunately, not everyone may be a candidate for stem cell transplantation. […] Overall, an estimated 50% to 80% of people with acute myeloid leukemia achieve complete remission after treatment. Complete remission happens more often in children and people under age 60. Remission may last for months or years.

• #153

  https://www.janssenwithme.com/en/blood-cancer/acute-myeloid-leukemia

  Because this is a fast-moving disease, treatments need to be immediate and aggressive once the best path has been identified. Regardless of the treatment specifics, plans generally follow a two-step process: Remission Induction Therapy: The goal is to kill all of the malignant leukaemia cells in the bone marrow. When enough of these cells have been killed, and the level of unhealthy to healthy blood cells has shifted favourably, your AML is considered to be in remission. Post-remission Therapy: The goal is to kill off any remaining unhealthy cells that may still persist and could cause a relapse.

• #154 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #155 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The final stages of AML can also impact a patient’s mental health. Patients may experience symptoms of anxiety and depression. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

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