Nowotwór
Zapobieganie i profilaktyka
Nowotwory stanowią istotne wyzwanie zdrowia publicznego, z możliwością zapobiegania 30-50% przypadków poprzez modyfikację czynników ryzyka i wdrożenie profilaktyki. Profilaktyka pierwotna obejmuje eliminację czynników ryzyka takich jak palenie tytoniu (odpowiedzialne za 1/3 nowotworów), nadwaga, niezdrowa dieta, brak aktywności fizycznej oraz nadmierne spożycie alkoholu (karcynogen grupy 1, powiązany z 7 typami nowotworów). Ochrona przed promieniowaniem UV, unikanie radonu i zanieczyszczeń powietrza również zmniejszają ryzyko. Szczepienia przeciwko HPV i WZW B redukują ryzyko nowotworów szyjki macicy i wątroby. Chemoprewencja z użyciem aspiryny (redukcja ryzyka raka jelita grubego o 27%) oraz selektywnych modulatorów receptora estrogenowego (SERM) u kobiet wysokiego ryzyka raka piersi stanowią dodatkowe narzędzia profilaktyczne.
- Nowotwór: Zapobieganie i Profilaktyka
- Profilaktyka pierwotna
- Chemoprewencja
- Profilaktyka wtórna
- Profilaktyka trzeciorzędowa
- Osoby z grupy wysokiego ryzyka
- Wyzwania i możliwości
- Kompleksowe podejście do profilaktyki nowotworów
- Osobiste strategie profilaktyczne
- Strategie społeczne i polityczne
- Strategie systemu opieki zdrowotnej
- Przyszłe kierunki w profilaktyce nowotworów
- Podsumowanie
Nowotwór: Zapobieganie i Profilaktyka
Nowotwór stanowi jedno z największych wyzwań dla zdrowia publicznego na całym świecie. Eksperci szacują, że około 30-50% wszystkich przypadków nowotworów można zapobiec poprzez modyfikację czynników ryzyka i wdrożenie odpowiednich strategii profilaktycznych. Profilaktyka jest najbardziej opłacalną długoterminową strategią kontroli nowotworów, oferującą możliwość znaczącego obniżenia zachorowalności i umieralności.12
Profilaktyka pierwotna
Profilaktyka pierwotna koncentruje się na działaniach mających na celu zmniejszenie prawdopodobieństwa wystąpienia nowotworu poprzez unikanie lub kontrolowanie znanych czynników ryzyka. Obejmuje ona modyfikacje stylu życia i środowiska oraz szczepienia ochronne.34
Czynniki stylu życia
Wiele czynników stylu życia ma udowodniony wpływ na ryzyko rozwoju nowotworów:
- Unikanie tytoniu – Dym tytoniowy zawiera ponad 7000 związków chemicznych, z czego co najmniej 250 jest szkodliwych, a co najmniej 69 powoduje nowotwory. Palenie tytoniu jest bezpośrednio związane z jedną trzecią wszystkich nowotworów. Zaprzestanie palenia lub nigdy nie rozpoczynanie znacząco zmniejsza ryzyko zachorowania i śmierci z powodu nowotworów płuc, nerek, pęcherza moczowego, głowy i szyi oraz kilku innych typów.56
- Kontrola masy ciała – Nadwaga i otyłość są powiązane z wieloma rodzajami nowotworów, takimi jak nowotwory przełyku, jelita grubego, piersi, endometrium i nerek. Utrzymywanie zdrowej masy ciała może obniżyć ryzyko wystąpienia co najmniej 13 różnych typów nowotworów.78
- Zdrowa dieta – Dieta bogata w owoce, warzywa, pełne ziarna i ryby, a uboga w przetworzone i czerwone mięso, tłuszcze zwierzęce i rafinowane węglowodany może mieć działanie ochronne przed nowotworami. Wykazano, że osoby stosujące dietę śródziemnomorską mają niższe ryzyko zachorowania na raka piersi.910
- Aktywność fizyczna – Regularna aktywność fizyczna może zmniejszyć ryzyko zachorowania na nowotwory piersi, jelita grubego i endometrium. Ćwiczenia pomagają obniżyć stan zapalny, regulują poziom insuliny, poprawiają funkcjonowanie układu odpornościowego i pomagają w utrzymaniu zdrowej masy ciała.1112
- Ograniczenie spożycia alkoholu – Alkohol jest klasyfikowany przez Międzynarodową Agencję Badań nad Rakiem jako substancja toksyczna, psychoaktywna i uzależniająca oraz karcynogen grupy 1, który jest przyczynowo powiązany z 7 typami nowotworów, w tym nowotworami przełyku, wątroby, jelita grubego i piersi.1314
Czynniki środowiskowe
Narażenie na czynniki środowiskowe może zwiększać ryzyko nowotworów:
- Ochrona przed promieniowaniem UV – Narażenie na wszystkie rodzaje promieniowania jonizującego zwiększa ryzyko różnych nowotworów złośliwych, w tym białaczki i nowotworów litych. Unikanie nadmiernej ekspozycji, stosowanie kremów z filtrem i odzieży ochronnej to skuteczne środki zapobiegawcze.1516
- Radon – Radon jest drugim najważniejszym czynnikiem ryzyka raka płuca po tytoniu. Jest to radioaktywny gaz, którego nie można zobaczyć, posmakować ani poczuć. Wdychanie radonu przez dłuższy czas może powodować raka płuc.17
- Zanieczyszczenie powietrza – Zarówno zanieczyszczenie powietrza w miastach, jak i dym wewnątrz pomieszczeń pochodzący z gospodarstw domowych stosujących paliwa stałe, mogą zwiększać ryzyko nowotworów.18
Czynniki infekcyjne
Infekcje powodujące nowotwory, takie jak wirusowe zapalenie wątroby i wirus brodawczaka ludzkiego (HPV), są odpowiedzialne za nawet 25% przypadków nowotworów w krajach o niskich i średnich dochodach. Dostępne są szczepionki przeciwko wirusowi zapalenia wątroby typu B i niektórym typom HPV, które mogą zmniejszyć ryzyko odpowiednio nowotworów wątroby i szyjki macicy.19
Szczepienia przeciwko tym infekcjom stanowią ważne narzędzie profilaktyczne:
- Szczepionka przeciwko HPV – Może zapobiegać infekcji HPV, która jest czynnikiem ryzyka rozwoju nowotworów odbytu, szyjki macicy i czterech innych nowotworów. Szczepionki przeciwko HPV (Gardasil i Cervarix) mogą w dużej mierze zapobiec wielu przypadkom tych nowotworów.2021
- Szczepionka przeciwko WZW B – Infekcja wirusem zapalenia wątroby typu B zwiększa ryzyko raka wątroby. Szczepienie przeciwko wirusowi zapalenia wątroby typu B może pomóc zapobiec rakowi wątroby.22
Chemoprewencja
Chemoprewencja to stosowanie substancji w celu obniżenia ryzyka zachorowania na nowotwory lub zapobiegania ich nawrotom. W tej dziedzinie wykazano skuteczność kilku środków:2324
- Kwas acetylosalicylowy (aspiryna) – Badania wykazały, że regularne stosowanie aspiryny i/lub innych niesteroidowych leków przeciwzapalnych (NLPZ) powoduje 20-40% zmniejszenie ryzyka rozwoju polipów jelita grubego i raka. Metaanaliza badań epidemiologicznych, obejmująca łącznie 16 105 przypadków, wykazała 27% zmniejszenie ryzyka raka jelita grubego przy stosowaniu aspiryny.2526
- Selektywne modulatory receptora estrogenowego (SERM) – Tamoksyfen i raloksyfen to leki na receptę, które są strukturalnie podobne do hormonu estrogenu. Oba mogą być stosowane do zmniejszenia ryzyka raka piersi u kobiet z grupy wysokiego ryzyka. Korzyści z pierwotnej profilaktyki są dobrze udokumentowane w długoterminowej metaanalizie SERM przeprowadzonej przez Cuzicka i wsp.2728
Profilaktyka wtórna
Profilaktyka wtórna koncentruje się na wczesnym wykrywaniu nowotworów lub stanów przednowotworowych, gdy leczenie jest najbardziej skuteczne. Głównym narzędziem profilaktyki wtórnej są badania przesiewowe.29
Badania przesiewowe
Regularne badania przesiewowe mogą pomóc w znalezieniu nowotworów we wczesnym stadium, kiedy leczenie jest najbardziej skuteczne. W niektórych przypadkach mogą nawet zapobiec rozwojowi nowotworu poprzez wykrycie i usunięcie zmian przednowotworowych.30
Najważniejsze programy badań przesiewowych obejmują:
- Rak szyjki macicy – Wysokiej jakości badania przesiewowe w kierunku raka szyjki macicy pomagają zmniejszyć częstość występowania raka szyjki macicy i umieralność z jego powodu. We Włoszech zapadalność na raka płaskonabłonkowego i inwazyjnego znacznie spadła z 11,6/100 000 do 8,7/100 000 od czasu wprowadzenia badań przesiewowych w kierunku raka szyjki macicy.31
- Rak jelita grubego – Wysokiej jakości badania przesiewowe w kierunku raka jelita grubego zmniejszyły częstość występowania raka jelita grubego o 33% i umieralność z powodu raka jelita grubego o 43%. Badanie przesiewowe może zarówno wykryć te nowotwory we wczesnym stadium, kiedy skuteczne leczenie jest bardziej prawdopodobne, jak i zapobiec ich rozwojowi.3233
- Rak piersi – Pomimo kontrowersji, badania przesiewowe w kierunku raka piersi niewątpliwie przyczyniły się do zmniejszenia umieralności z powodu nowotworów o 30-50%.34
- Rak płuc – Amerykańskie Towarzystwo Raka zaleca coroczne badania przesiewowe w kierunku raka płuc za pomocą niskodawkowej tomografii komputerowej (LDCT) dla osób w wieku od 50 do 80 lat, które palą lub paliły w przeszłości i mają co najmniej 20-paczkoletnią historię palenia.35
Profilaktyka trzeciorzędowa
Profilaktyka trzeciorzędowa koncentruje się na osobach, które już przebyły nowotwór, i ma na celu zapobieganie nawrotom lub rozwojowi wtórnych nowotworów, a także poprawę jakości życia. Obejmuje to zarządzanie efektami leczenia i długoterminowymi konsekwencjami choroby nowotworowej.3637
Chirurgia zmniejszająca ryzyko
W przypadku osób z najwyższym ryzykiem nowotworów, na przykład nosicieli mutacji zarodkowych (np. mutacje APC, BRCA1, BRCA2 lub CDH1), profilaktyka nowotworowa może ostatecznie obejmować chirurgię profilaktyczną.38
Osoby, które mają odziedziczony zespół zwany dziedzicznym rozlanym rakiem żołądka, mają mutacje w genie CDH1, które znacznie zwiększają ich ryzyko zachorowania na raka żołądka. Ryzyko jest tak wysokie, że zaleca się im profilaktyczne usunięcie żołądka.39
Osoby z grupy wysokiego ryzyka
Osoby z wyższym niż przeciętne ryzykiem zachorowania na nowotwór, na przykład z powodu dziedzicznej predyspozycji, wymagają dodatkowych podejść do profilaktyki terapeutycznej, oprócz ogólnych zaleceń.40
Czynniki wysokiego ryzyka mogą obejmować:
- Rodzinną historię nowotworów, szczególnie u krewnych pierwszego stopnia (matka, siostra, córka) lub wielu krewnych drugiego lub trzeciego stopnia (dziadek, ciotka, kuzyn) z diagnozą nowotworu przed 60 rokiem życia.41
- Mutacje genetyczne, takie jak mutacje w genach BRCA1 lub BRCA2, które znacznie zwiększają ryzyko raka piersi i jajnika.42
- Przebyte biopsje przednowotworowe.43
- Osobista historia nieinwazyjnego raka przewodowego.44
- Radioterapia klatki piersiowej jako leczenie nowotworu przed 30 rokiem życia.45
Wyzwania i możliwości
Chociaż interwencje profilaktyczne, w tym zmiany stylu życia i zachowań oraz stosowanie medycyny profilaktycznej, wykazały skuteczność w zmniejszaniu ryzyka nowotworów, wciąż wymagają one znacznie większego wysiłku w zakresie rozwoju i wdrażania, począwszy od badań podstawowych, a skończywszy na poziomie edukacyjnym i komunikacyjnym, aby w pełni zrealizować swój potencjał.46
Pomimo długoterminowych danych obserwacyjnych potwierdzających początkowe korzystne wyniki wszystkich badań profilaktycznych, rutynowe stosowanie profilaktyki pierwotnej jest nadal bardzo niskie, co obecnie ogranicza jej skuteczność na poziomie populacyjnym.47
Wdrażanie i polityka
Wdrażanie świadomości i edukacji na temat profilaktyki nowotworów jest obowiązkowe zarówno dla ogółu społeczeństwa, jak i personelu medycznego. Obecnie dostępne dowody pokazują, że programy profilaktyczne są ważną bronią w walce z rakiem i mogą przyczynić się do zmniejszenia zarówno zapadalności na raka, jak i umieralności.4849
Na poziomie UE profilaktyka jest jednym z kluczowych obszarów działania europejskiego planu walki z rakiem, który będzie dotyczył tytoniu, szkodliwego spożycia alkoholu, zanieczyszczenia środowiska i substancji niebezpiecznych.50
Kompleksowe podejście do profilaktyki nowotworów
Kompleksowe podejście do profilaktyki nowotworów obejmuje wiele poziomów interwencji, od indywidualnych wyborów stylu życia po politykę zdrowia publicznego.51
Osobiste strategie profilaktyczne
Osoby mogą zmniejszyć swoje ryzyko zachorowania na nowotwór poprzez:
- Niepalenie tytoniu lub rzucenie palenia52
- Utrzymywanie zdrowej masy ciała53
- Regularna aktywność fizyczna54
- Zdrowa dieta bogata w owoce, warzywa i pełne ziarna55
- Ograniczenie lub unikanie alkoholu56
- Ochrona skóry przed słońcem57
- Unikanie narażenia na znane substancje rakotwórcze58
- Udział w programach szczepień przeciwko HPV i WZW B59
- Regularne badania przesiewowe w kierunku nowotworów60
Strategie społeczne i polityczne
Na poziomie społecznym i politycznym, skuteczne strategie profilaktyczne obejmują:
- Politykę kontroli tytoniu i alkoholu61
- Promowanie aktywności fizycznej i zdrowego odżywiania62
- Programy szczepień finansowane ze środków publicznych63
- Organizowanie i finansowanie programów badań przesiewowych64
- Regulacje dotyczące substancji rakotwórczych w miejscu pracy i środowisku65
- Edukacja publiczna na temat profilaktyki nowotworów66
Strategie systemu opieki zdrowotnej
Systemy opieki zdrowotnej mogą wspierać profilaktykę nowotworów poprzez:
- Zapewnienie dostępu do badań przesiewowych67
- Szkolenie personelu medycznego w zakresie interwencji profilaktycznych68
- Wdrażanie protokołów oceny ryzyka i poradnictwa69
- Ułatwianie dostępu do szczepień70
- Wspieranie rzucania palenia i innych interwencji związanych ze stylem życia71
- Prowadzenie programów oceny ryzyka genetycznego i poradnictwa72
Przyszłe kierunki w profilaktyce nowotworów
Badacze stale pracują nad nowymi strategiami profilaktyki nowotworów, w tym:7374
- Szczepionki terapeutyczne przeciwko nowotworom75
- Personalizowane podejścia do chemoprewencji76
- Zaawansowane techniki identyfikacji ryzyka genetycznego77
- Bardziej precyzyjne i mniej inwazyjne metody badań przesiewowych78
- Interwencje ukierunkowane na komórki macierzyste nowotworu79
Podsumowanie
Profilaktyka nowotworów stanowi kluczowy element strategii kontroli nowotworów, oferując możliwość znaczącego zmniejszenia obciążenia chorobami nowotworowymi. Szacuje się, że około 30-50% wszystkich przypadków nowotworów można zapobiec poprzez unikanie czynników ryzyka, wczesne wykrywanie i poddawanie się regularnym badaniom przesiewowym.8081
Dowody kliniczne przekonująco wykazały, że możliwe jest obniżenie częstości występowania nowotworów, przynajmniej w przypadku raka piersi i jelita grubego, poprzez stosowanie medycyny profilaktycznej. Kompleksowe podejście do profilaktyki nowotworów, obejmujące zmiany stylu życia, szczepienia, badania przesiewowe i interwencje chemoprewencyjne, oferuje najlepszą strategię zmniejszenia obciążenia nowotworami w populacji.82
Wdrażanie świadomości i edukacji na temat profilaktyki nowotworów jest niezbędne zarówno dla ogółu społeczeństwa, jak i pracowników służby zdrowia, aby w pełni wykorzystać potencjał już dostępnych strategii profilaktycznych i przyspieszyć rozwój nowych podejść do profilaktyki nowotworów.83
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Materiały źródłowe
- #1https://www.who.int/activities/preventing-cancer
Between 30-50% of all cancer cases are preventable. Prevention offers the most cost-effective long-term strategy for the control of cancer. WHO works with Member States to strengthen national policies and programmes to raise awareness and, reduce exposure to cancer risk factors, and also ensure that people are provided with the information and support they need to adopt healthy lifestyles. […] Tobacco smoke has more than 7000 chemicals, at least 250 are known to be harmful and at least 69 are known to cause cancer. […] Alcohol, as classified by the International Agency for Research on Cancer, is a toxic, psychoactive, and dependence-producing substance and a Group 1 carcinogen that is causally linked to 7 types of cancer, including oesophagus, liver, colorectal, and breast cancers. […] Overweight and obesity are linked to many types of cancer such as oesophagus, colorectal, breast, endometrial and kidney. Regular physical activity, and maintaining a healthy body weight, and a healthy diet can risk.
- #2https://www.who.int/health-topics/cancer
Between 30% and 50% of cancer deaths could be prevented by modifying or avoiding key risk factors and implementing existing evidence-based prevention strategies. […] The cancer burden can also be reduced through early detection of cancer and management of patients who develop cancer. […] Prevention also offers the most cost-effective long-term strategy for the control of cancer. […] Modifying or avoiding the following key risk factors can help prevent cancer: avoid tobacco use, including cigarettes and smokeless tobacco; maintain a healthy weight; eat a healthy diet with plenty of fruit and vegetables; exercise regularly; limit alcohol use; practice safe sex; get vaccinated against hepatitis B and human papillomavirus (HPV); reduce exposure to ultraviolet radiation; prevent unnecessary ionizing radiation exposure (e.g. minimize occupational exposure, ensure safe and appropriate medical use of radiation in diagnosis and treatment); avoid urban air pollution and indoor smoke from household use of solid fuels; get regular medical care; and some chronic infections are also risk factors for cancer. People in low- and middle-income countries are more likely to develop cancer through chronic infections.
- #3 Cancer Prevention Overview – NCIhttps://www.cancer.gov/about-cancer/causes-prevention/patient-prevention-overview-pdq
Cancer prevention is action taken to lower the chance of getting cancer. By preventing cancer, the number of new cases of cancer is lowered. Hopefully, this will reduce the burden of cancer and lower the number of deaths caused by cancer. […] Scientists are studying many different ways to help prevent cancer, including: Ways to avoid or control things known to cause cancer. Changes in diet and lifestyle. Finding precancerous conditions early. Chemoprevention (medicines to treat a precancerous condition or to keep cancer from starting). Risk-reducing surgery. […] Scientists study risk factors and protective factors to find ways to prevent new cancers from starting. Anything that increases your chance of developing cancer is called a cancer risk factor; anything that decreases your chance of developing cancer is called a cancer protective factor.
- #4 Prevention of Cancer – Cancer – Merck Manual Consumer Versionhttps://www.merckmanuals.com/home/cancer/prevention-and-treatment-of-cancer/prevention-of-cancer
There are many different types of cancer, with different causes and risk factors. Doctors estimate that about 40% of cancers are preventable. […] However, some general strategies do reduce the risk of cancer or cancer complications in many people. These general strategies fall into 3 categories: Primary prevention: Steps people can take to lessen their chance of developing certain types of cancer […] Secondary prevention: Directed at people who may already have some kind of cancer but have not developed symptoms […] Tertiary prevention: Measures aimed at slowing down the effects of a cancer to prevent complications. […] Screening is part of secondary prevention of certain cancers. It involves using information about a person, particularly their risk factors for cancer and results of their physical examination, to guide testing to look for unrecognized cancer. Early detection of cancerous or precancerous growths can save lives. So it is important that people get the recommended screening tests for cancer.
- #5https://www.who.int/activities/preventing-cancer
Between 30-50% of all cancer cases are preventable. Prevention offers the most cost-effective long-term strategy for the control of cancer. WHO works with Member States to strengthen national policies and programmes to raise awareness and, reduce exposure to cancer risk factors, and also ensure that people are provided with the information and support they need to adopt healthy lifestyles. […] Tobacco smoke has more than 7000 chemicals, at least 250 are known to be harmful and at least 69 are known to cause cancer. […] Alcohol, as classified by the International Agency for Research on Cancer, is a toxic, psychoactive, and dependence-producing substance and a Group 1 carcinogen that is causally linked to 7 types of cancer, including oesophagus, liver, colorectal, and breast cancers. […] Overweight and obesity are linked to many types of cancer such as oesophagus, colorectal, breast, endometrial and kidney. Regular physical activity, and maintaining a healthy body weight, and a healthy diet can risk.
- #6 Prevention of Cancer – Cancer – Merck Manual Consumer Versionhttps://www.merckmanuals.com/home/cancer/prevention-and-treatment-of-cancer/prevention-of-cancer
Reducing the risk of certain cancers may be possible through dietary and other lifestyle changes. How much risk can be reduced depends on the specific cancer. […] Decreasing alcohol intake can reduce the risk of head and neck, liver, and esophageal cancer. […] Decreasing fat intake appears to reduce the risk of breast and colon cancers. […] Limiting the intake of processed meat and increasing the intake of whole grains and fruits and vegetables may decrease risk of some types of cancer. […] Tobacco use is directly associated with one-third of all cancers. Not smoking and avoiding exposure to tobacco smoke can greatly reduce the risk of lung, kidney, bladder, head and neck, and several other cancer types. […] Overweight and obesity are risk factors for cancer, especially breast cancer, colon cancer, endometrial cancer, esophageal cancer, kidney cancer, and pancreatic cancer. People should try to maintain a healthy weight through both diet and exercise. Physical activity itself may reduce the risk of breast, endometrial, and prostate cancers.
- #7https://www.who.int/activities/preventing-cancer
Between 30-50% of all cancer cases are preventable. Prevention offers the most cost-effective long-term strategy for the control of cancer. WHO works with Member States to strengthen national policies and programmes to raise awareness and, reduce exposure to cancer risk factors, and also ensure that people are provided with the information and support they need to adopt healthy lifestyles. […] Tobacco smoke has more than 7000 chemicals, at least 250 are known to be harmful and at least 69 are known to cause cancer. […] Alcohol, as classified by the International Agency for Research on Cancer, is a toxic, psychoactive, and dependence-producing substance and a Group 1 carcinogen that is causally linked to 7 types of cancer, including oesophagus, liver, colorectal, and breast cancers. […] Overweight and obesity are linked to many types of cancer such as oesophagus, colorectal, breast, endometrial and kidney. Regular physical activity, and maintaining a healthy body weight, and a healthy diet can risk.
- #8 Can cancer be prevented? | How to reduce your risk of cancerhttps://www.cancerresearchuk.org/about-cancer/causes-of-cancer/can-cancer-be-prevented-0
Not all cancers can be prevented but there are things you can do to reduce your risk. […] These include not smoking, keeping a healthy weight and staying safe in the sun. […] Research has shown that things like stopping smoking, keeping a healthy weight, staying safe in the sun, cutting down on alcohol and eating a healthy, balanced diet can reduce the risk of cancer. […] There are no guarantees when it comes to cancer, but making healthy changes does help reduce your risk. […] Not smoking is the best thing you can do to reduce your risk of cancer, as smoking is the biggest cause of cancer. […] Being a healthy weight has lots of health benefits, including reducing the risk of at least 13 different types of cancer. […] Being safe in the sun reduces the risk of skin cancer. […] Cutting down on alcohol reduces your risk of 7 types of cancer. […] Having a healthy, balanced diet can help reduce your risk of cancer. […] The HPV vaccine helps to prevent cancer by protecting against human papillomavirus (HPV).
- #9 Adult healthhttps://www.mayoclinic.org/healthy-lifestyle/adult-health/in-depth/cancer-prevention/art-20044816
Cancer prevention: 7 tips to reduce your risk […] Concerned about cancer prevention? Take charge by making changes such as eating healthy foods and getting regular screenings. […] But experts know that certain lifestyle choices can affect the chances of getting cancer. Try these lifestyle tips to help prevent cancer. […] A great way to help prevent cancer is to not use tobacco. If you want to quit tobacco, ask a healthcare professional about products that can help you stop smoking and other ways of quitting. […] Eating healthy foods isn’t a sure way to prevent cancer. But it might lower the risk. […] People who eat a Mediterranean diet have a lower risk of breast cancer. […] Being at a healthy weight might lower the risk of some types of cancer. […] Physical activity counts too.
- #10 Cancer prevention – Wikipediahttps://en.wikipedia.org/wiki/Cancer_prevention
Future preventive screening measures can be additionally improved by minimizing invasiveness and increasing specificity by taking individual biological makeup into account, also known as „population-based personalized cancer screening.” […] Dietary recommendations for reducing cancer risk typically include an emphasis on vegetables, fruit, whole grains, and fish, and an avoidance of processed and red meat (beef, pork, lamb), animal fats, and refined carbohydrates. The World Cancer Research Fund recommends a diet rich in fruits and vegetables to reduce the risk of cancer. A diet rich in foods of plant origin, including non-starchy fruits and vegetables, non-starchy roots and tubers, and whole grains, may have protective effects against cancer. […] Consumption of coffee is associated with a reduced risk of liver cancer and endometrial cancer. Additionally, a higher coffee intake was shown to be related to a lower risk of melanoma and oral/pharyngeal cancer. However, a higher risk of childhood acute lymphocytic leukemia and bladder cancer actually is associated with higher coffee intake. However, it’s important to note that these claims are associations and there is not strong evidence that validates the effects of coffee consumption and cancer risk.
- #11 Cancer Prevention | CancerQuesthttps://cancerquest.org/patients/cancer-prevention
In addition to these general guidelines, there are several specific compounds that have exhibited evidence that they may contribute to cancer prevention. […] The following cancer prevention methods are described below in more detail. […] Exercise can cause many changes in the human body. The types of changes depend on the amount and type of exercise. Exercise increases the amount of blood pumped by the heart (called cardiac output). This, in turn, leads to increased oxygen and blood flow. The increased heart rate also triggers the release of hormones. […] Physical activity is strongly associated with lower risk of cancer at seven sites: bladder, colon, breast, endometrial, lung, esophageal, kidney, and stomach gastric. Physical activity has also been linked to reductions in pancreatic and ovarian cancer.
- #12 Cancer Prevention | CancerQuesthttps://cancerquest.org/patients/cancer-prevention
Exercise lowers sex hormone levels. Estrogen is a female sex hormone that maintains the female reproductive system. While estrogen is essential for the female body, women with elevated levels of estrogen and other sex hormones (androgens) are at a higher risk for developing breast cancer. Research has shown that exercise of sufficient frequency and intensity causes significant decreases in levels of these hormones. […] Exercise prevents high insulin levels. Insulin resistance leads to elevated blood levels of insulin, as well as elevated amounts of glucose in the blood stream. Insulin increases the chances of tumor development by activating cell proliferation, or cells dividing rapidly, and the inhibition of apoptosis, or programmed cell death. […] Exercise reduces inflammation and regulates insulin levels.
- #13https://www.who.int/activities/preventing-cancer
Between 30-50% of all cancer cases are preventable. Prevention offers the most cost-effective long-term strategy for the control of cancer. WHO works with Member States to strengthen national policies and programmes to raise awareness and, reduce exposure to cancer risk factors, and also ensure that people are provided with the information and support they need to adopt healthy lifestyles. […] Tobacco smoke has more than 7000 chemicals, at least 250 are known to be harmful and at least 69 are known to cause cancer. […] Alcohol, as classified by the International Agency for Research on Cancer, is a toxic, psychoactive, and dependence-producing substance and a Group 1 carcinogen that is causally linked to 7 types of cancer, including oesophagus, liver, colorectal, and breast cancers. […] Overweight and obesity are linked to many types of cancer such as oesophagus, colorectal, breast, endometrial and kidney. Regular physical activity, and maintaining a healthy body weight, and a healthy diet can risk.
- #14 Ways to reduce your risk of getting cancerhttps://www2.hse.ie/conditions/cancer/reduce-risk/
Physical activity can reduce your risk of some types of cancer, such as breast, bowel and womb cancer. […] Carrying excess weight or living with obesity can increase your risk of some cancers. […] Alcohol increases your risk of at least 7 types of cancer. […] Ultraviolet (UV) radiation from the sun and sunbeds can damage skin and increase your risk of skin cancer. […] Reduce your risk of cancer by taking part in free cancer screening programmes. […] Some cancers are caused by viruses. […] Make sure your children take part in vaccination programmes for hepatitis B and human papillomavirus (HPV). […] You may be exposed to cancer-causing substances in your workplace. […] Radon is a radioactive gas in the air that can cause lung cancer. […] If you breastfeed your baby this will reduce your risk of breast cancer. […] The combined oral contraceptive pill can slightly increase the risk of breast and cervical cancers. […] Finding cancer early means you are more likely to survive it.
- #15https://www.who.int/activities/preventing-cancer
Cancer causing infections, such as hepatitis and human papilloma virus (HPV), are responsible for up to 25% of cancer cases in low- and middle-income countries. Vaccines are available for hepatitis B virus and some types of HPV, and can reduce the risk of liver and cervical cancers, respectively. […] Exposure to all types of ionizing radiation increases the risk of various types of malignancy including leukaemia and a number of solid tumours. Risks increase when the exposure occurs at a young age and also when the exposure amount is higher. Avoiding excessive exposure, and using sunscreen and protective clothing are effective preventive measures.
- #16 Prevention of Cancer – Cancer – Merck Manual Consumer Versionhttps://www.merckmanuals.com/home/cancer/prevention-and-treatment-of-cancer/prevention-of-cancer
Avoiding sun exposure (especially during the middle of the day) can reduce the risk of skin cancers. Covering exposed skin and using sunscreens with a sun protection factor (SPF) of at least 30 that protect against both ultraviolet A and ultraviolet B light also help reduce the risk of skin cancer. […] Vaccines can prevent certain types of cancer that are caused by viruses. For example, certain strains of sexually transmitted human papillomavirus (HPV) cause cervical cancer, anal cancer, and some forms of head and neck cancer. Vaccination against HPV can largely prevent many cases of these cancers. […] As another example, infection with hepatitis B virus increases the risk of liver cancer. Vaccination against hepatitis B virus can help prevent liver cancer. […] Aspirin use may reduce the risk of colorectal cancer or result in earlier diagnosis because of bleeding. […] For women with symptoms of menopause, taking hormone therapy (for example, estrogen and progesterone) may increase the risk of breast cancer. Women who have symptoms of menopause should carefully consider the risks and benefits of using hormone therapy and consult their health care professional.
- #17 Cancer Prevention | Huntsman Cancer Institute | University of Utah Healthhttps://healthcare.utah.edu/huntsmancancerinstitute/screening-prevention/prevention
No single food prevents cancer, but eating a variety of plant-based foods lowers your risk of getting cancer. Eating healthy helps you keep a healthy weight and supports your immune system. Healthy foods contain compounds that repair cells and help fight cancer before it starts. […] The vaccines for two infectionsâHPV and hepatitis Bâcan help prevent certain cancers. […] Exposure to the sun, including tanning and sunburns, can increase your risk of developing skin cancer. […] Radon is the second leading cause of lung cancer after tobacco. Radon is a radioactive gasâimpossible to see, taste, or smell. Breathing in radon over time may cause lung cancer. Testing is the only way to know if your home has radon.
- #18https://www.who.int/health-topics/cancer
Between 30% and 50% of cancer deaths could be prevented by modifying or avoiding key risk factors and implementing existing evidence-based prevention strategies. […] The cancer burden can also be reduced through early detection of cancer and management of patients who develop cancer. […] Prevention also offers the most cost-effective long-term strategy for the control of cancer. […] Modifying or avoiding the following key risk factors can help prevent cancer: avoid tobacco use, including cigarettes and smokeless tobacco; maintain a healthy weight; eat a healthy diet with plenty of fruit and vegetables; exercise regularly; limit alcohol use; practice safe sex; get vaccinated against hepatitis B and human papillomavirus (HPV); reduce exposure to ultraviolet radiation; prevent unnecessary ionizing radiation exposure (e.g. minimize occupational exposure, ensure safe and appropriate medical use of radiation in diagnosis and treatment); avoid urban air pollution and indoor smoke from household use of solid fuels; get regular medical care; and some chronic infections are also risk factors for cancer. People in low- and middle-income countries are more likely to develop cancer through chronic infections.
- #19https://www.who.int/activities/preventing-cancer
Cancer causing infections, such as hepatitis and human papilloma virus (HPV), are responsible for up to 25% of cancer cases in low- and middle-income countries. Vaccines are available for hepatitis B virus and some types of HPV, and can reduce the risk of liver and cervical cancers, respectively. […] Exposure to all types of ionizing radiation increases the risk of various types of malignancy including leukaemia and a number of solid tumours. Risks increase when the exposure occurs at a young age and also when the exposure amount is higher. Avoiding excessive exposure, and using sunscreen and protective clothing are effective preventive measures.
- #20 National Cancer Prevention Month | Cancer Awareness Months | AACRhttps://www.aacr.org/patients-caregivers/awareness-months/national-cancer-prevention-month/
February is National Cancer Prevention Month. […] Research shows that more than 40% of these cases and nearly half of the deaths can be attributed to preventable causes: smoking, excess body weight, physical inactivity, and excessive exposure to the sun, among others. […] This means that steps such as quitting smoking (or never starting in the first place), maintaining a healthy weight, exercising regularly, protecting your skin from the sun, and getting vaccinated against the pathogens that cause certain cancers can dramatically reduce your risk of cancer in many cases. […] Its imperative that we implement effective, evidence-based practices that reduce modifiable cancer risk factors for everyone. […] The human papillomavirus (HPV) vaccine can prevent HPV, a risk factor for developing anal, cervical, and four other cancers.
- #21https://pmc.ncbi.nlm.nih.gov/articles/PMC4718348/
There are two kinds of anti-cancer vaccines: preventive (or prophylactic) and therapeutic vaccines. The former include anti-HPV vaccines (Gardasil and Cervarix) for the prevention of cervical cancer, and anti-HBV vaccines for the prevention of hepatocellular carcinoma. […] In conclusion, prevention programs are an important weapon in the fight against cancer, and currently available evidence shows that they can contribute to reducing both the incidence of cancer and mortality.
- #22 Prevention of Cancer – Cancer – Merck Manual Consumer Versionhttps://www.merckmanuals.com/home/cancer/prevention-and-treatment-of-cancer/prevention-of-cancer
Avoiding sun exposure (especially during the middle of the day) can reduce the risk of skin cancers. Covering exposed skin and using sunscreens with a sun protection factor (SPF) of at least 30 that protect against both ultraviolet A and ultraviolet B light also help reduce the risk of skin cancer. […] Vaccines can prevent certain types of cancer that are caused by viruses. For example, certain strains of sexually transmitted human papillomavirus (HPV) cause cervical cancer, anal cancer, and some forms of head and neck cancer. Vaccination against HPV can largely prevent many cases of these cancers. […] As another example, infection with hepatitis B virus increases the risk of liver cancer. Vaccination against hepatitis B virus can help prevent liver cancer. […] Aspirin use may reduce the risk of colorectal cancer or result in earlier diagnosis because of bleeding. […] For women with symptoms of menopause, taking hormone therapy (for example, estrogen and progesterone) may increase the risk of breast cancer. Women who have symptoms of menopause should carefully consider the risks and benefits of using hormone therapy and consult their health care professional.
- #23 Cancer Prevention Overview – NCIhttps://www.cancer.gov/about-cancer/causes-prevention/patient-prevention-overview-pdq
Not smoking or quitting smoking lowers the risk of getting cancer and dying from cancer. […] Two vaccines to prevent infection by cancer-causing agents have been developed and approved by the U.S. Food and Drug Administration (FDA). […] Chemoprevention is the use of substances to lower the risk of cancer, or keep it from recurring. […] Studies have shown that weight loss surgery lowers cancer risk. […] Other types of surgery can help lower the risk of cancer. […] Aspirin has not been shown to prevent most cancers. […] Vitamin and dietary supplements have not been shown to prevent cancer. […] New ways to prevent cancer are being studied in clinical trials.
- #24 What is Chemoprevention? | OncoLinkhttps://www.oncolink.org/risk-and-prevention/prevention-screening/what-is-chemoprevention
Chemoprevention is the use of a medication, vitamin, or supplement to stop cancer from happening. This is most often used for people who have a high risk of cancer. They may have a strong family history, carry a certain gene, or have a personal health history that makes their risk higher. […] It can be used in three ways: Primary prevention: Prevent cancer in a healthy person. […] Secondary prevention: Prevent a pre-cancerous area from becoming cancer. […] Tertiary prevention: Used for a person who has already had cancer, to prevent them from developing another cancer. […] Studies have found that regular use of aspirin and/or other non-steroidal anti-inflammatory drugs (NSAIDs) results in a 20-40% reduction in the risk of developing colorectal polyps and cancer. […] Chemoprevention is also being studied in other cancers such as head and neck, lung, and skin cancer. […] Talk about the risks of any chemoprevention with your healthcare provider. In some cases, there are more risks than benefits, and you may decide chemoprevention is not right for you. In other people, the benefit of cancer prevention may make the side effects tolerable.
- #25 What is Chemoprevention? | OncoLinkhttps://www.oncolink.org/risk-and-prevention/prevention-screening/what-is-chemoprevention
Chemoprevention is the use of a medication, vitamin, or supplement to stop cancer from happening. This is most often used for people who have a high risk of cancer. They may have a strong family history, carry a certain gene, or have a personal health history that makes their risk higher. […] It can be used in three ways: Primary prevention: Prevent cancer in a healthy person. […] Secondary prevention: Prevent a pre-cancerous area from becoming cancer. […] Tertiary prevention: Used for a person who has already had cancer, to prevent them from developing another cancer. […] Studies have found that regular use of aspirin and/or other non-steroidal anti-inflammatory drugs (NSAIDs) results in a 20-40% reduction in the risk of developing colorectal polyps and cancer. […] Chemoprevention is also being studied in other cancers such as head and neck, lung, and skin cancer. […] Talk about the risks of any chemoprevention with your healthcare provider. In some cases, there are more risks than benefits, and you may decide chemoprevention is not right for you. In other people, the benefit of cancer prevention may make the side effects tolerable.
- #26 Therapeutic cancer prevention: achievements and ongoing challenges â a focus on breast and colorectal cancerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6396378/
A metaanalysis of epidemiological studies, including a total of 16 105 cases, showed a 27% risk reduction of CRC with aspirin use. […] As a result of the current clinical evidence, aspirin is gaining acceptance as a colorectal cancer preventive therapy in agestratified groups, as highlighted by the recently updated US Preventive Services Task Force guidelines which recommend aspirin for primary cancer prevention in individuals aged 5059 years, who also have a 10% or greater 10year risk of cardiovascular disease. […] Clinical evidence has convincingly demonstrated that it is possible to lower cancer incidence, at least for breast and colorectal cancer, through the use of preventive medicine. […] Implementing awareness and education on cancer prevention is mandatory for both the general public and healthcare professionals.
- #27 Therapeutic cancer prevention: achievements and ongoing challenges â a focus on breast and colorectal cancerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6396378/
In individuals with a higher than average cancer risk, for example due to an inherited predisposition, then additional therapeutic prevention approaches are warranted in addition to any general recommendations. […] For the highest risk cohorts of the germline mutation carriers (e.g., mutations of APC, BRCA1, BRCA2, or CDH1), cancer prevention can ultimately extend to prophylactic surgery. […] The benefits of primary prevention are well documented in the longterm SERMs metaanalysis by Cuzick et al. […] Even though the longterm followup data reinforce the initial beneficial findings from all the prevention trials, the routine use of primary prevention is still very low, which is currently limiting its effectiveness at a population level. […] Aspirin and nonsteroidal antiinflammatory drug (NSAID) use has been associated with reduced risk of CRC in several studies, initially with contradictory results but longer followup subsequently confirmed the positive effects.
- #28 Prevention of Cancer – Cancer – Merck Manual Consumer Versionhttps://www.merckmanuals.com/home/cancer/prevention-and-treatment-of-cancer/prevention-of-cancer
Avoiding sun exposure (especially during the middle of the day) can reduce the risk of skin cancers. Covering exposed skin and using sunscreens with a sun protection factor (SPF) of at least 30 that protect against both ultraviolet A and ultraviolet B light also help reduce the risk of skin cancer. […] Vaccines can prevent certain types of cancer that are caused by viruses. For example, certain strains of sexually transmitted human papillomavirus (HPV) cause cervical cancer, anal cancer, and some forms of head and neck cancer. Vaccination against HPV can largely prevent many cases of these cancers. […] As another example, infection with hepatitis B virus increases the risk of liver cancer. Vaccination against hepatitis B virus can help prevent liver cancer. […] Aspirin use may reduce the risk of colorectal cancer or result in earlier diagnosis because of bleeding. […] For women with symptoms of menopause, taking hormone therapy (for example, estrogen and progesterone) may increase the risk of breast cancer. Women who have symptoms of menopause should carefully consider the risks and benefits of using hormone therapy and consult their health care professional.
- #29 Prevention of Cancer – Cancer – Merck Manual Consumer Versionhttps://www.merckmanuals.com/home/cancer/prevention-and-treatment-of-cancer/prevention-of-cancer
There are many different types of cancer, with different causes and risk factors. Doctors estimate that about 40% of cancers are preventable. […] However, some general strategies do reduce the risk of cancer or cancer complications in many people. These general strategies fall into 3 categories: Primary prevention: Steps people can take to lessen their chance of developing certain types of cancer […] Secondary prevention: Directed at people who may already have some kind of cancer but have not developed symptoms […] Tertiary prevention: Measures aimed at slowing down the effects of a cancer to prevent complications. […] Screening is part of secondary prevention of certain cancers. It involves using information about a person, particularly their risk factors for cancer and results of their physical examination, to guide testing to look for unrecognized cancer. Early detection of cancerous or precancerous growths can save lives. So it is important that people get the recommended screening tests for cancer.
- #30 Adult healthhttps://www.mayoclinic.org/healthy-lifestyle/adult-health/in-depth/cancer-prevention/art-20044816
Skin cancer is one of the most common kinds of cancer and one of the easiest to prevent. […] Protecting against certain viral infections can help protect against cancer. […] Talk to a healthcare professional about getting vaccines to prevent the following: Hepatitis B can raise the risk of getting liver cancer. […] HPV is a sexually transmitted virus that can cause cervical cancer and other genital cancers. […] Some behaviors carry a high risk of infections that can raise the risk of getting cancer. […] Do regular self-exams. Get screenings for cancers, such as cancer of the skin, colon, cervix and breast. These efforts raise the chances of finding cancer early. That’s when treatment is most likely to work.
- #31https://pmc.ncbi.nlm.nih.gov/articles/PMC4718348/
Primary and secondary prevention should therefore be regarded as a priority for global cancer control. […] Organized screening is a highly standardized form of „systems screening”; as it is constantly monitored through quality check and process indicators and relies on evidence-based protocols and guidelines, it differs from opportunistic or spontaneous screening. […] High-quality cervical screening helps to reduce the incidence of cervical cancer and mortality. In Italy, the incidence of squamous cell and invasive cancers has significantly decreased from 11.6/100,000 to 8.7/100,000 since the introduction of cervical screening. […] High-quality CRC screening has been seen to reduce the incidence of CRC by 33% and mortality due to CRC by 43%. […] Despite these controversies, breast cancer screening has undoubtedly contributed to reducing cancer mortality by 30-50%.
- #32https://pmc.ncbi.nlm.nih.gov/articles/PMC4718348/
Primary and secondary prevention should therefore be regarded as a priority for global cancer control. […] Organized screening is a highly standardized form of „systems screening”; as it is constantly monitored through quality check and process indicators and relies on evidence-based protocols and guidelines, it differs from opportunistic or spontaneous screening. […] High-quality cervical screening helps to reduce the incidence of cervical cancer and mortality. In Italy, the incidence of squamous cell and invasive cancers has significantly decreased from 11.6/100,000 to 8.7/100,000 since the introduction of cervical screening. […] High-quality CRC screening has been seen to reduce the incidence of CRC by 33% and mortality due to CRC by 43%. […] Despite these controversies, breast cancer screening has undoubtedly contributed to reducing cancer mortality by 30-50%.
- #33 Cancer Risk Reduction and Prevention | The AACRhttps://www.aacr.org/patients-caregivers/about-cancer/cancer-prevention/
Exposure to ultraviolet (UV) light from the sun or indoor tanning is the predominant cause of all three main types of skin cancer basal cell carcinoma, squamous cell carcinoma, and melanoma. Adopting sun-safe habits and avoiding the use of indoor tanning devices can decrease the incidence of skin cancer. […] Infections with cancer-related pathogens account for about one in five cancer diagnoses worldwide, and taking measures to prevent and treat these infections can help prevent certain cancers. […] Screening for colorectal cancer, the second leading cause of cancer death in the United States, by colonoscopy can both detect these cancers at an early stage, when successful treatment is more likely, and prevent them from developing in the first place. […] If everyone followed colorectal cancer screening guidelines, at least 60 percent of colorectal cancer deaths in the United States could be avoided.
- #34https://pmc.ncbi.nlm.nih.gov/articles/PMC4718348/
Primary and secondary prevention should therefore be regarded as a priority for global cancer control. […] Organized screening is a highly standardized form of „systems screening”; as it is constantly monitored through quality check and process indicators and relies on evidence-based protocols and guidelines, it differs from opportunistic or spontaneous screening. […] High-quality cervical screening helps to reduce the incidence of cervical cancer and mortality. In Italy, the incidence of squamous cell and invasive cancers has significantly decreased from 11.6/100,000 to 8.7/100,000 since the introduction of cervical screening. […] High-quality CRC screening has been seen to reduce the incidence of CRC by 33% and mortality due to CRC by 43%. […] Despite these controversies, breast cancer screening has undoubtedly contributed to reducing cancer mortality by 30-50%.
- #35 Prevention and Early Detection Guidelines | American Cancer Societyhttps://www.cancer.org/health-care-professionals/american-cancer-society-prevention-early-detection-guidelines.html
The American Cancer Society recommends that adults at average risk for colorectal cancer undergo regular screening starting at age 45, with either a high-sensitivity stool-based test or a structural (visual) examination. […] The American Cancer Society recommends yearly screening for lung cancer with a low-dose CT (LDCT) scan for people aged 50 to 80 years who smoke or used to smoke and have at least a 20 pack-year history of smoking. […] The American Cancer Society recommends that asymptomatic men who have at least a 10-year life expectancy have an opportunity to make an informed decision with their health care provider about screening for prostate cancer after they receive information about the uncertainties, risks, and potential benefits associated with prostate cancer screening. […] Since 1991, the American Cancer Society has published guidelines that focus on nutrition and physical activity, aimed at advising health care professionals, policy makers, and the general public about dietary and other lifestyle practices that reduce cancer risk. […] The American Cancer Society recommends HPV vaccination for boys and girls between age 9 and 12.
- #36 Prevention of Cancer – Cancer – Merck Manual Consumer Versionhttps://www.merckmanuals.com/home/cancer/prevention-and-treatment-of-cancer/prevention-of-cancer
There are many different types of cancer, with different causes and risk factors. Doctors estimate that about 40% of cancers are preventable. […] However, some general strategies do reduce the risk of cancer or cancer complications in many people. These general strategies fall into 3 categories: Primary prevention: Steps people can take to lessen their chance of developing certain types of cancer […] Secondary prevention: Directed at people who may already have some kind of cancer but have not developed symptoms […] Tertiary prevention: Measures aimed at slowing down the effects of a cancer to prevent complications. […] Screening is part of secondary prevention of certain cancers. It involves using information about a person, particularly their risk factors for cancer and results of their physical examination, to guide testing to look for unrecognized cancer. Early detection of cancerous or precancerous growths can save lives. So it is important that people get the recommended screening tests for cancer.
- #37 What is Chemoprevention? | OncoLinkhttps://www.oncolink.org/risk-and-prevention/prevention-screening/what-is-chemoprevention
Chemoprevention is the use of a medication, vitamin, or supplement to stop cancer from happening. This is most often used for people who have a high risk of cancer. They may have a strong family history, carry a certain gene, or have a personal health history that makes their risk higher. […] It can be used in three ways: Primary prevention: Prevent cancer in a healthy person. […] Secondary prevention: Prevent a pre-cancerous area from becoming cancer. […] Tertiary prevention: Used for a person who has already had cancer, to prevent them from developing another cancer. […] Studies have found that regular use of aspirin and/or other non-steroidal anti-inflammatory drugs (NSAIDs) results in a 20-40% reduction in the risk of developing colorectal polyps and cancer. […] Chemoprevention is also being studied in other cancers such as head and neck, lung, and skin cancer. […] Talk about the risks of any chemoprevention with your healthcare provider. In some cases, there are more risks than benefits, and you may decide chemoprevention is not right for you. In other people, the benefit of cancer prevention may make the side effects tolerable.
- #38 Therapeutic cancer prevention: achievements and ongoing challenges â a focus on breast and colorectal cancerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6396378/
In individuals with a higher than average cancer risk, for example due to an inherited predisposition, then additional therapeutic prevention approaches are warranted in addition to any general recommendations. […] For the highest risk cohorts of the germline mutation carriers (e.g., mutations of APC, BRCA1, BRCA2, or CDH1), cancer prevention can ultimately extend to prophylactic surgery. […] The benefits of primary prevention are well documented in the longterm SERMs metaanalysis by Cuzick et al. […] Even though the longterm followup data reinforce the initial beneficial findings from all the prevention trials, the routine use of primary prevention is still very low, which is currently limiting its effectiveness at a population level. […] Aspirin and nonsteroidal antiinflammatory drug (NSAID) use has been associated with reduced risk of CRC in several studies, initially with contradictory results but longer followup subsequently confirmed the positive effects.
- #39https://winshipcancer.emory.edu/cancer-types-and-treatments/stomach-cancer/prevention.php
People who have an inherited syndrome called hereditary diffuse gastric cancer have mutations in the CDH1 gene that significantly increase their risk of stomach cancer. The risk is so high, in fact, that its recommended they have their stomachs removed preemptively. […] Having a gastric ulcer in the stomach caused by an H. pylori infection can increase a persons risk of developing stomach cancer. In any event, having a stomach ulcer does not mean you will develop stomach cancer. Advances in ulcer management over the years has greatly improved stomach cancer incidence. […] As we continue to learn more about stomach cancer and its causes, the following stomach cancer prevention recommendations may help you reduce your risk: Not using any tobacco products, Not drinking alcohol, Maintaining a healthy body weight (e.g. body mass index below 25), Being physically active every day, Eating a diet rich in fruits and vegetables (particularly citrus fruits) and low in processed meats, Seeking treatment for an H. pylori infection.
- #40 Therapeutic cancer prevention: achievements and ongoing challenges â a focus on breast and colorectal cancerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6396378/
In individuals with a higher than average cancer risk, for example due to an inherited predisposition, then additional therapeutic prevention approaches are warranted in addition to any general recommendations. […] For the highest risk cohorts of the germline mutation carriers (e.g., mutations of APC, BRCA1, BRCA2, or CDH1), cancer prevention can ultimately extend to prophylactic surgery. […] The benefits of primary prevention are well documented in the longterm SERMs metaanalysis by Cuzick et al. […] Even though the longterm followup data reinforce the initial beneficial findings from all the prevention trials, the routine use of primary prevention is still very low, which is currently limiting its effectiveness at a population level. […] Aspirin and nonsteroidal antiinflammatory drug (NSAID) use has been associated with reduced risk of CRC in several studies, initially with contradictory results but longer followup subsequently confirmed the positive effects.
- #41 Breast Cancer Prevention | The University of Kansas Cancer Centerhttps://www.kucancercenter.org/outreach/prevention/preventable-cancers/breast-cancer
Certain risk factors can increase a womans chance of developing breast cancer. […] Our high-risk breast cancer care specialists offer a full range of breast cancer prevention services. […] Generally, women who have a first-degree relative (mother, sister or daughter) or multiple second- or third-degree relatives (grandparent, aunt or cousin) who were diagnosed with breast cancer under the age of 60 are considered at increased risk of developing the disease. […] In addition, your chance for developing the disease increases if you have 1 or more of these breast cancer risk factors: Family history of breast or ovarian cancer, Breast cancer in a male relative, Genetic testing indicating a mutation in certain genes (such as BRCA1 or BRCA2 genes), Precancerous breast biopsy, Personal history of noninvasive ductal cancer, Dense breast tissue, Chest radiation as a treatment for cancer under age 30.
- #42 Breast Cancer Prevention | The University of Kansas Cancer Centerhttps://www.kucancercenter.org/outreach/prevention/preventable-cancers/breast-cancer
Certain risk factors can increase a womans chance of developing breast cancer. […] Our high-risk breast cancer care specialists offer a full range of breast cancer prevention services. […] Generally, women who have a first-degree relative (mother, sister or daughter) or multiple second- or third-degree relatives (grandparent, aunt or cousin) who were diagnosed with breast cancer under the age of 60 are considered at increased risk of developing the disease. […] In addition, your chance for developing the disease increases if you have 1 or more of these breast cancer risk factors: Family history of breast or ovarian cancer, Breast cancer in a male relative, Genetic testing indicating a mutation in certain genes (such as BRCA1 or BRCA2 genes), Precancerous breast biopsy, Personal history of noninvasive ductal cancer, Dense breast tissue, Chest radiation as a treatment for cancer under age 30.
- #43 Breast Cancer Prevention | The University of Kansas Cancer Centerhttps://www.kucancercenter.org/outreach/prevention/preventable-cancers/breast-cancer
Certain risk factors can increase a womans chance of developing breast cancer. […] Our high-risk breast cancer care specialists offer a full range of breast cancer prevention services. […] Generally, women who have a first-degree relative (mother, sister or daughter) or multiple second- or third-degree relatives (grandparent, aunt or cousin) who were diagnosed with breast cancer under the age of 60 are considered at increased risk of developing the disease. […] In addition, your chance for developing the disease increases if you have 1 or more of these breast cancer risk factors: Family history of breast or ovarian cancer, Breast cancer in a male relative, Genetic testing indicating a mutation in certain genes (such as BRCA1 or BRCA2 genes), Precancerous breast biopsy, Personal history of noninvasive ductal cancer, Dense breast tissue, Chest radiation as a treatment for cancer under age 30.
- #44 Breast Cancer Prevention | The University of Kansas Cancer Centerhttps://www.kucancercenter.org/outreach/prevention/preventable-cancers/breast-cancer
Certain risk factors can increase a womans chance of developing breast cancer. […] Our high-risk breast cancer care specialists offer a full range of breast cancer prevention services. […] Generally, women who have a first-degree relative (mother, sister or daughter) or multiple second- or third-degree relatives (grandparent, aunt or cousin) who were diagnosed with breast cancer under the age of 60 are considered at increased risk of developing the disease. […] In addition, your chance for developing the disease increases if you have 1 or more of these breast cancer risk factors: Family history of breast or ovarian cancer, Breast cancer in a male relative, Genetic testing indicating a mutation in certain genes (such as BRCA1 or BRCA2 genes), Precancerous breast biopsy, Personal history of noninvasive ductal cancer, Dense breast tissue, Chest radiation as a treatment for cancer under age 30.
- #45 Breast Cancer Prevention | The University of Kansas Cancer Centerhttps://www.kucancercenter.org/outreach/prevention/preventable-cancers/breast-cancer
Certain risk factors can increase a womans chance of developing breast cancer. […] Our high-risk breast cancer care specialists offer a full range of breast cancer prevention services. […] Generally, women who have a first-degree relative (mother, sister or daughter) or multiple second- or third-degree relatives (grandparent, aunt or cousin) who were diagnosed with breast cancer under the age of 60 are considered at increased risk of developing the disease. […] In addition, your chance for developing the disease increases if you have 1 or more of these breast cancer risk factors: Family history of breast or ovarian cancer, Breast cancer in a male relative, Genetic testing indicating a mutation in certain genes (such as BRCA1 or BRCA2 genes), Precancerous breast biopsy, Personal history of noninvasive ductal cancer, Dense breast tissue, Chest radiation as a treatment for cancer under age 30.
- #46 Therapeutic cancer prevention: achievements and ongoing challenges â a focus on breast and colorectal cancerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6396378/
The constant increase of cancer incidence and the huge costs of new treatments make cancer prevention a crucial goal in order to maintain sustainable public health systems across the world. […] Cancer prevention medicine can be considered to be treatment of premalignant cells or preneoplastic conditions. […] In the field of cancer prevention medicine, breast and colon cancer demonstrates the strongest clinical evidence that pharmacological intervention can lower cancer risk. […] Preventive interventions, including lifestyle and behavioral changes and use of preventive medicine (or therapies), still need far more effort in terms of development and implementation, from basic research up to the educational and communication level, to realize their true potential. […] Therapeutic prevention can be described as primary, secondary, or tertiary, according to the population being targeted and stage of cancer development.
- #47 Therapeutic cancer prevention: achievements and ongoing challenges â a focus on breast and colorectal cancerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6396378/
In individuals with a higher than average cancer risk, for example due to an inherited predisposition, then additional therapeutic prevention approaches are warranted in addition to any general recommendations. […] For the highest risk cohorts of the germline mutation carriers (e.g., mutations of APC, BRCA1, BRCA2, or CDH1), cancer prevention can ultimately extend to prophylactic surgery. […] The benefits of primary prevention are well documented in the longterm SERMs metaanalysis by Cuzick et al. […] Even though the longterm followup data reinforce the initial beneficial findings from all the prevention trials, the routine use of primary prevention is still very low, which is currently limiting its effectiveness at a population level. […] Aspirin and nonsteroidal antiinflammatory drug (NSAID) use has been associated with reduced risk of CRC in several studies, initially with contradictory results but longer followup subsequently confirmed the positive effects.
- #48 Therapeutic cancer prevention: achievements and ongoing challenges â a focus on breast and colorectal cancerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6396378/
A metaanalysis of epidemiological studies, including a total of 16 105 cases, showed a 27% risk reduction of CRC with aspirin use. […] As a result of the current clinical evidence, aspirin is gaining acceptance as a colorectal cancer preventive therapy in agestratified groups, as highlighted by the recently updated US Preventive Services Task Force guidelines which recommend aspirin for primary cancer prevention in individuals aged 5059 years, who also have a 10% or greater 10year risk of cardiovascular disease. […] Clinical evidence has convincingly demonstrated that it is possible to lower cancer incidence, at least for breast and colorectal cancer, through the use of preventive medicine. […] Implementing awareness and education on cancer prevention is mandatory for both the general public and healthcare professionals.
- #49https://pmc.ncbi.nlm.nih.gov/articles/PMC4718348/
There are two kinds of anti-cancer vaccines: preventive (or prophylactic) and therapeutic vaccines. The former include anti-HPV vaccines (Gardasil and Cervarix) for the prevention of cervical cancer, and anti-HBV vaccines for the prevention of hepatocellular carcinoma. […] In conclusion, prevention programs are an important weapon in the fight against cancer, and currently available evidence shows that they can contribute to reducing both the incidence of cancer and mortality.
- #50 Cancer prevention | Knowledge for policyhttps://knowledge4policy.ec.europa.eu/cancer/cancer-prevention-2024_en
Targeted health promotion measures can considerably reduce cancer risk. […] It is estimated that over 40% of cancers could be prevented through healthierful diets, physical activity, smoking cessation, reducing alcohol consumption and reduced exposure to environmental pollution. […] Different modifiable factors may increase or decrease the risk for developing cancer. It is therefore important that primary prevention efforts address the whole breadth of factors, aiming to establish cancer-protective behaviours from a young age. […] At an EU level, prevention is one of the key action areas of the Europe’s Beating Cancer Plan that will address tobacco, harmful alcohol consumption, environmental pollution and hazardous substances. […] The Health Promotion and Disease Prevention Knowledge Gateway provides reliable and up-to-date information on the health effects of such modifiable risk factors, i.e. smoking, alcohol consumption, different nutrition aspects (for example whole grain, or fruit and vegetables) and Physical activity and sedentary behaviour, as well as the recommended policies to tackle the modifiable risk factors and promote healthier behaviours.
- #51 Our Cancer Prevention Recommendations | World Cancer Research Fundhttps://www.wcrf.org/preventing-cancer/cancer-prevention/our-cancer-prevention-recommendations/
Experts now believe that up to 40% of cancer cases are preventable. Our Cancer Prevention Recommendations are a blueprint for how to reduce your risk of cancer. […] Our evidence from massive population studies and from researchers who look at cells in a laboratory suggests that around 40% of cancer cases could be prevented if people follow our Recommendations and if governments create environments where its easier to live healthily. […] Our Cancer Prevention Recommendations devised by experts and rigorously tested by independent scientists to confirm they work are a blueprint for individuals and societies to reduce cancer. […] Not smoking, and staying safe in the sun, are also important to reduce your cancer risk. […] The Recommendations should be seen as a package unfortunately, you cant just pick and choose if you want to reduce your cancer risk.
- #52 Can cancer be prevented? | How to reduce your risk of cancerhttps://www.cancerresearchuk.org/about-cancer/causes-of-cancer/can-cancer-be-prevented-0
Not all cancers can be prevented but there are things you can do to reduce your risk. […] These include not smoking, keeping a healthy weight and staying safe in the sun. […] Research has shown that things like stopping smoking, keeping a healthy weight, staying safe in the sun, cutting down on alcohol and eating a healthy, balanced diet can reduce the risk of cancer. […] There are no guarantees when it comes to cancer, but making healthy changes does help reduce your risk. […] Not smoking is the best thing you can do to reduce your risk of cancer, as smoking is the biggest cause of cancer. […] Being a healthy weight has lots of health benefits, including reducing the risk of at least 13 different types of cancer. […] Being safe in the sun reduces the risk of skin cancer. […] Cutting down on alcohol reduces your risk of 7 types of cancer. […] Having a healthy, balanced diet can help reduce your risk of cancer. […] The HPV vaccine helps to prevent cancer by protecting against human papillomavirus (HPV).
- #53 Women’s healthhttps://www.mayoclinic.org/healthy-lifestyle/womens-health/in-depth/breast-cancer-prevention/art-20044676
Breast cancer prevention starts with healthy habits such as limiting alcohol and staying physically active. Learn what you can do to lower your breast cancer risk. […] Research shows that lifestyle changes can lower the chances of getting breast cancer, even in people at high risk. To lower your risk: […] Limit or stay away from alcohol. It’s safest not to drink alcohol. But if you do drink it, enjoy it in moderation. The more alcohol you have, the greater your risk of getting breast cancer. […] Stay at a healthy weight. Ask a member of your health care team whether your weight is healthy. If it is, work to maintain that weight. If you need to lose weight, ask your health care professional how to do so. […] Get active. Physical activity can help you stay at a healthy weight, which helps prevent breast cancer.
- #54 Cancer Prevention | Huntsman Cancer Institute | University of Utah Healthhttps://healthcare.utah.edu/huntsmancancerinstitute/screening-prevention/prevention
In addition to cancer prevention, it is important to check for cancer or conditions that may lead to cancer. This is called cancer screening. […] You can take actions to lower your risk or chances of getting cancer. These actions are called cancer prevention. Making healthy lifestyle choices can prevent about half of all cancers. Here are examples of healthy lifestyles choices: […] A person can control some risk factors, like alcohol consumption, use of tobacco, exposure to sunlight, diet, obesity, and exposure to infections and infectious agents. […] Quit tobaccoâbetter yet, never startâto lower your risk for cancer and other diseases. Tobacco causes many types of cancer. It is the leading cause of cancer-related death. […] Moving your body throughout the day has many benefits that help lower your risk of getting cancer and many other diseases. Exercise helps lower inflammation that can increase your cancer risk. It also helps keep damaged cells from turning into cancer.
- #55 Women’s healthhttps://www.mayoclinic.org/healthy-lifestyle/womens-health/in-depth/breast-cancer-prevention/art-20044676
Breastfeed. If you have a baby, breastfeeding might play a role in helping prevent breast cancer. The longer you breastfeed, the greater the protective effect. […] Limit hormone therapy after menopause. Combination hormone therapy uses estrogen and progestin. It may raise the risk of breast cancer. […] If you smoke, quit. Some research suggests that smoking tobacco raises the risk of breast cancer. […] Eating a healthy diet might lower your risk of some types of cancer. […] Some research suggests that people who eat a Mediterranean diet might have a lower risk of breast cancer, especially after menopause. […] A balanced diet can help you stay at a healthy weight. And healthy weight is a key factor in helping prevent breast cancer. […] There’s some evidence that hormonal types of birth control raise the risk of breast cancer.
- #56 Women’s healthhttps://www.mayoclinic.org/healthy-lifestyle/womens-health/in-depth/breast-cancer-prevention/art-20044676
Breast cancer prevention starts with healthy habits such as limiting alcohol and staying physically active. Learn what you can do to lower your breast cancer risk. […] Research shows that lifestyle changes can lower the chances of getting breast cancer, even in people at high risk. To lower your risk: […] Limit or stay away from alcohol. It’s safest not to drink alcohol. But if you do drink it, enjoy it in moderation. The more alcohol you have, the greater your risk of getting breast cancer. […] Stay at a healthy weight. Ask a member of your health care team whether your weight is healthy. If it is, work to maintain that weight. If you need to lose weight, ask your health care professional how to do so. […] Get active. Physical activity can help you stay at a healthy weight, which helps prevent breast cancer.
- #57 Cancer Prevention | Huntsman Cancer Institute | University of Utah Healthhttps://healthcare.utah.edu/huntsmancancerinstitute/screening-prevention/prevention
No single food prevents cancer, but eating a variety of plant-based foods lowers your risk of getting cancer. Eating healthy helps you keep a healthy weight and supports your immune system. Healthy foods contain compounds that repair cells and help fight cancer before it starts. […] The vaccines for two infectionsâHPV and hepatitis Bâcan help prevent certain cancers. […] Exposure to the sun, including tanning and sunburns, can increase your risk of developing skin cancer. […] Radon is the second leading cause of lung cancer after tobacco. Radon is a radioactive gasâimpossible to see, taste, or smell. Breathing in radon over time may cause lung cancer. Testing is the only way to know if your home has radon.
- #58 Ways to reduce your risk of getting cancerhttps://www2.hse.ie/conditions/cancer/reduce-risk/
Physical activity can reduce your risk of some types of cancer, such as breast, bowel and womb cancer. […] Carrying excess weight or living with obesity can increase your risk of some cancers. […] Alcohol increases your risk of at least 7 types of cancer. […] Ultraviolet (UV) radiation from the sun and sunbeds can damage skin and increase your risk of skin cancer. […] Reduce your risk of cancer by taking part in free cancer screening programmes. […] Some cancers are caused by viruses. […] Make sure your children take part in vaccination programmes for hepatitis B and human papillomavirus (HPV). […] You may be exposed to cancer-causing substances in your workplace. […] Radon is a radioactive gas in the air that can cause lung cancer. […] If you breastfeed your baby this will reduce your risk of breast cancer. […] The combined oral contraceptive pill can slightly increase the risk of breast and cervical cancers. […] Finding cancer early means you are more likely to survive it.
- #59 Reduce your risk | Canadian Cancer Societyhttps://cancer.ca/en/cancer-information/reduce-your-risk
Did you know that about 4 in 10 cancer cases in Canada can be prevented? Its true. There are things we eat, drink, breathe and do that affect our cancer risk. […] Follow these recommendations and help reduce your cancer risk. […] The birth control pill and hormone replacement therapy may increase your risk of cancer. Understand the risks and benefits. […] Some viruses cause cancer. Check with your healthcare provider about whether a hepatitis B or HPV vaccine is a good idea for you. […] Learn how to reduce your exposure to cancer-causing substances (carcinogens). […] We recognize that making healthy behaviour changes can be difficult to achieve alone, thats why were here to help. […] It teaches you how 16 factors affect your risk of getting cancer and how you can reduce your risk by making simple changes.
- #60 Cancer Prevention and Screening Resource Center | Rutgers Cancer Institute of New Jerseyhttps://cinj.org/patient-care/cancer-prevention-and-screening-resource-center
Cancer is the result of the uncontrolled growth and spread of abnormal cells within the body. Some of these abnormal cells can be discovered through a cancer screening. Preventative tests can lead to early detection of cancers, some of which if discovered early can lead to successful outcomes. Resources available through Rutgers Cancer Institute and ScreenNJ describe risk factors and other information that can be useful in speaking to a health care provider about a screening schedule. […] There are guidelines and recommendations for cancer screenings. However, individuals at high risk may need to be screened sooner or more frequently. Speak to your healthcare provider about the cancer screenings that are right for you. Most screenings are covered by insurance. […] Women are encouraged to know how their breasts normally feel and report any breast changes promptly to their healthcare providers.
- #61 Cancer prevention | Knowledge for policyhttps://knowledge4policy.ec.europa.eu/cancer/cancer-prevention-2024_en
Targeted health promotion measures can considerably reduce cancer risk. […] It is estimated that over 40% of cancers could be prevented through healthierful diets, physical activity, smoking cessation, reducing alcohol consumption and reduced exposure to environmental pollution. […] Different modifiable factors may increase or decrease the risk for developing cancer. It is therefore important that primary prevention efforts address the whole breadth of factors, aiming to establish cancer-protective behaviours from a young age. […] At an EU level, prevention is one of the key action areas of the Europe’s Beating Cancer Plan that will address tobacco, harmful alcohol consumption, environmental pollution and hazardous substances. […] The Health Promotion and Disease Prevention Knowledge Gateway provides reliable and up-to-date information on the health effects of such modifiable risk factors, i.e. smoking, alcohol consumption, different nutrition aspects (for example whole grain, or fruit and vegetables) and Physical activity and sedentary behaviour, as well as the recommended policies to tackle the modifiable risk factors and promote healthier behaviours.
- #62 Cancer prevention | Knowledge for policyhttps://knowledge4policy.ec.europa.eu/cancer/cancer-prevention-2024_en
Encouraging and promoting healthy lifestyles is key for the successful prevention of non-communicable disease, including cancer. Access to healthy diets and physical activity from an early age can help create health-promoting habits and behaviours that track into adulthood. […] The European Code Against Cancer (ECAC) is an initiative of the European Commission and the result of a project coordinated by the International Agency for Research on Cancer. The code aims to inform people about actions they can take to reduce their risk of cancer and relate to: tobacco, second-hand smoke, healthy body weight, physical activity, diet, alcohol consumption, sun/UV exposure, environmental pollutants, radiation, breastfeeding and hormonal therapy, infections and vaccination, and screening. The code is based on scientific evidence on cancer prevention.
- #63 Cancer Prevention in Actionhttps://www.health.ny.gov/diseases/cancer/prevention_in_action/
Community Cancer Prevention in Action (CPiA) is a New York State Department of Health program supporting local cancer prevention and risk reduction interventions using a policy, systems and environmental (PSE) change approach. […] Grantees build awareness of and support for cancer prevention policies in their local communities. They work to decrease exposure to ultraviolet radiation, increase human papillomavirus (HPV) vaccination rates among adolescents, and increase awareness of and support for cancer prevention PSE changes. Select grantees also work to increase cancer screening rates for breast, cervical, and colorectal cancers. […] Grantees conduct education and mobilize their local communities to: Increase the adoption of sun safety policies and practices in community settings. Increase the number of community education interventions to build support for the HPV vaccine as cancer prevention. Increase the adoption of worksite policies that establish paid time off benefits for employees to obtain cancer screenings. […] Cancer Prevention Resources: Sun Safety (cdc.gov) Everyone Can Play a Role to Reduce Skin Cancer (cdc.gov) Developing a Paid Leave Policy for Cancer Paid Leave: A Benefit for Employers and Employees Offering Paid Time Off for Cancer Screenings The HPV Vaccine for Parents (cdc.gov)
- #64 Department of Health | Cancer | Office of Cancer Control and Preventionhttps://www.nj.gov/health/ces/public/resources/occp.shtml
The New Jersey Cancer Education and Early Detection (NJCEED) Program provides comprehensive outreach, education and screening services for breast, cervical, colorectal and prostate cancers. Persons eligible for these services must be at or below 250% of the federal poverty level and be uninsured or under-insured. […] The Office of Cancer Control and Prevention (OCCP) coordinates comprehensive cancer control efforts in New Jersey. Comprehensive cancer control is a collaborative process by which a community and its partners pool resources to reduce illness and death due to cancer through prevention, early detection, treatment, rehabilitation, and palliation. […] The OCCP also participates in the national efforts of the CDC to establish state-based comprehensive cancer control plans and conduct prevention of cancer risk factors, enhance early detection of preventable cancers and facilitate survivorship through the activities of its Regional Chronic Disease Coalitions.
- #65 Ways to reduce your risk of getting cancerhttps://www2.hse.ie/conditions/cancer/reduce-risk/
Physical activity can reduce your risk of some types of cancer, such as breast, bowel and womb cancer. […] Carrying excess weight or living with obesity can increase your risk of some cancers. […] Alcohol increases your risk of at least 7 types of cancer. […] Ultraviolet (UV) radiation from the sun and sunbeds can damage skin and increase your risk of skin cancer. […] Reduce your risk of cancer by taking part in free cancer screening programmes. […] Some cancers are caused by viruses. […] Make sure your children take part in vaccination programmes for hepatitis B and human papillomavirus (HPV). […] You may be exposed to cancer-causing substances in your workplace. […] Radon is a radioactive gas in the air that can cause lung cancer. […] If you breastfeed your baby this will reduce your risk of breast cancer. […] The combined oral contraceptive pill can slightly increase the risk of breast and cervical cancers. […] Finding cancer early means you are more likely to survive it.
- #66 Cancer Prevention in Actionhttps://www.health.ny.gov/diseases/cancer/prevention_in_action/
Community Cancer Prevention in Action (CPiA) is a New York State Department of Health program supporting local cancer prevention and risk reduction interventions using a policy, systems and environmental (PSE) change approach. […] Grantees build awareness of and support for cancer prevention policies in their local communities. They work to decrease exposure to ultraviolet radiation, increase human papillomavirus (HPV) vaccination rates among adolescents, and increase awareness of and support for cancer prevention PSE changes. Select grantees also work to increase cancer screening rates for breast, cervical, and colorectal cancers. […] Grantees conduct education and mobilize their local communities to: Increase the adoption of sun safety policies and practices in community settings. Increase the number of community education interventions to build support for the HPV vaccine as cancer prevention. Increase the adoption of worksite policies that establish paid time off benefits for employees to obtain cancer screenings. […] Cancer Prevention Resources: Sun Safety (cdc.gov) Everyone Can Play a Role to Reduce Skin Cancer (cdc.gov) Developing a Paid Leave Policy for Cancer Paid Leave: A Benefit for Employers and Employees Offering Paid Time Off for Cancer Screenings The HPV Vaccine for Parents (cdc.gov)
- #67 Department of Health | Cancer | Office of Cancer Control and Preventionhttps://www.nj.gov/health/ces/public/resources/occp.shtml
The New Jersey Cancer Education and Early Detection (NJCEED) Program provides comprehensive outreach, education and screening services for breast, cervical, colorectal and prostate cancers. Persons eligible for these services must be at or below 250% of the federal poverty level and be uninsured or under-insured. […] The Office of Cancer Control and Prevention (OCCP) coordinates comprehensive cancer control efforts in New Jersey. Comprehensive cancer control is a collaborative process by which a community and its partners pool resources to reduce illness and death due to cancer through prevention, early detection, treatment, rehabilitation, and palliation. […] The OCCP also participates in the national efforts of the CDC to establish state-based comprehensive cancer control plans and conduct prevention of cancer risk factors, enhance early detection of preventable cancers and facilitate survivorship through the activities of its Regional Chronic Disease Coalitions.
- #68https://cancer.wvumedicine.org/about-us/inside-the-institute/cancer-prevention-and-control/
Early detection of cancer can save lives. The most common cancers in West Virginia lung, breast, prostate, and colorectal can all be caught and treated early through routine screening tests. […] A key part of the teams mission is to reduce cancer health disparities and remove barriers to cancer care. […] Cancer Prevention and Control is proud to be the home of the WVU Cancer Institute Mobile Cancer Screening Program, providing mammography and lung cancer screening. […] Mobile cancer services help West Virginians in our most rural areas have access to potentially life-saving cancer screening. […] Because primary care drives cancer screenings, we keep them up to date on the latest screening guidelines for different types of cancer and teach best practices for cancer screenings, with the goal of helping each primary care center improve their screening rates.
- #69 Cancer Prevention Center | MD Anderson Cancer Centerhttps://www.mdanderson.org/patients-family/diagnosis-treatment/care-centers-clinics/cancer-prevention-center.html
When seen for evaluation, you will have your risk of developing cancer assessed, be counseled regarding a healthy lifestyle as well as other ways to reduce cancer risk (e.g., medications), and receive screening recommendations based on your individualized cancer risk. […] The best reason to come to MD Anderson for cancer screenings is that we make recommendations women dont often get elsewhere. […] Many women are also not told about medications like tamoxifen that can reduce their risk of breast cancer, which we might recommend based on their personal risk factors.
- #70 Cancer Prevention in Actionhttps://www.health.ny.gov/diseases/cancer/prevention_in_action/
Community Cancer Prevention in Action (CPiA) is a New York State Department of Health program supporting local cancer prevention and risk reduction interventions using a policy, systems and environmental (PSE) change approach. […] Grantees build awareness of and support for cancer prevention policies in their local communities. They work to decrease exposure to ultraviolet radiation, increase human papillomavirus (HPV) vaccination rates among adolescents, and increase awareness of and support for cancer prevention PSE changes. Select grantees also work to increase cancer screening rates for breast, cervical, and colorectal cancers. […] Grantees conduct education and mobilize their local communities to: Increase the adoption of sun safety policies and practices in community settings. Increase the number of community education interventions to build support for the HPV vaccine as cancer prevention. Increase the adoption of worksite policies that establish paid time off benefits for employees to obtain cancer screenings. […] Cancer Prevention Resources: Sun Safety (cdc.gov) Everyone Can Play a Role to Reduce Skin Cancer (cdc.gov) Developing a Paid Leave Policy for Cancer Paid Leave: A Benefit for Employers and Employees Offering Paid Time Off for Cancer Screenings The HPV Vaccine for Parents (cdc.gov)
- #71 Cancer Prevention and Control Programhttps://lombardi.georgetown.edu/research/programs/cancer-prevention-control/
The programs membership is also instrumental in leading translational working groups around focal and emerging areas of cancer control and prevention, including care delivery research, epidemiology and modeling, translational genomics, and in studying the burdens of cancer among older adults and long-term cancer survivors. […] The Cancer Prevention and Control (CPC) Program is part of the LCCC and hence all non therapeutic Interventional and Observational studies must be registered and reported in OnCore and CTRP in a timely fashion.
- #72 Cancer Prevention and Risk Reduction | Dana-Farber Cancer Institutehttps://www.dana-farber.org/patient-family/cancer-prevention-risk
The Pediatric Cancer Genetic Risk Program at Dana-Farber/Boston Children’s provides cancer risk assessment for children, comprehensive recommendations for managing cancer risk in children, and psychosocial support for families affected by hereditary cancer. […] Our nutrition experts help patients follow a healthy diet during and after cancer treatment. […] This much is known: A sedentary lifestyle raises the risk of cancer, while physical activity even moderate exercise can reduce the risk not only of developing cancer but having a recurrence following treatment. […] With an estimated 8,500 new cases of skin cancer diagnosed in the U.S. every day, it is important that you not only protect yourself from the suns UV rays, but also regularly check your skin for anything out of the ordinary.
- #73 National Cancer Prevention Month | Cancer Awareness Months | AACRhttps://www.aacr.org/patients-caregivers/awareness-months/national-cancer-prevention-month/
Scientists are investigating new ways to prevent breast cancer, with clinical trials involving vaccines, personalized doses of tamoxifen, and targeted inhibition of the cells that give rise to breast cancer. […] A lack of awareness regarding the fecal immunochemical test (FIT) used to screen for colorectal cancer, the HIV vaccine, and whole-exome sequencing is leading to some groups failing to benefit from these cancer screening and prevention methods. […] The AACR is committed to advancing the science of cancer prevention. […] With its funding partners, the AACR makes grants available to scientists studying prevention of a variety of cancers.
- #74 Cancer Prevention Overview – NCIhttps://www.cancer.gov/about-cancer/causes-prevention/patient-prevention-overview-pdq
Not smoking or quitting smoking lowers the risk of getting cancer and dying from cancer. […] Two vaccines to prevent infection by cancer-causing agents have been developed and approved by the U.S. Food and Drug Administration (FDA). […] Chemoprevention is the use of substances to lower the risk of cancer, or keep it from recurring. […] Studies have shown that weight loss surgery lowers cancer risk. […] Other types of surgery can help lower the risk of cancer. […] Aspirin has not been shown to prevent most cancers. […] Vitamin and dietary supplements have not been shown to prevent cancer. […] New ways to prevent cancer are being studied in clinical trials.
- #75https://pmc.ncbi.nlm.nih.gov/articles/PMC4718348/
There are two kinds of anti-cancer vaccines: preventive (or prophylactic) and therapeutic vaccines. The former include anti-HPV vaccines (Gardasil and Cervarix) for the prevention of cervical cancer, and anti-HBV vaccines for the prevention of hepatocellular carcinoma. […] In conclusion, prevention programs are an important weapon in the fight against cancer, and currently available evidence shows that they can contribute to reducing both the incidence of cancer and mortality.
- #76 National Cancer Prevention Month | Cancer Awareness Months | AACRhttps://www.aacr.org/patients-caregivers/awareness-months/national-cancer-prevention-month/
Scientists are investigating new ways to prevent breast cancer, with clinical trials involving vaccines, personalized doses of tamoxifen, and targeted inhibition of the cells that give rise to breast cancer. […] A lack of awareness regarding the fecal immunochemical test (FIT) used to screen for colorectal cancer, the HIV vaccine, and whole-exome sequencing is leading to some groups failing to benefit from these cancer screening and prevention methods. […] The AACR is committed to advancing the science of cancer prevention. […] With its funding partners, the AACR makes grants available to scientists studying prevention of a variety of cancers.
- #77 Cancer prevention – Wikipediahttps://en.wikipedia.org/wiki/Cancer_prevention
Future preventive screening measures can be additionally improved by minimizing invasiveness and increasing specificity by taking individual biological makeup into account, also known as „population-based personalized cancer screening.” […] Dietary recommendations for reducing cancer risk typically include an emphasis on vegetables, fruit, whole grains, and fish, and an avoidance of processed and red meat (beef, pork, lamb), animal fats, and refined carbohydrates. The World Cancer Research Fund recommends a diet rich in fruits and vegetables to reduce the risk of cancer. A diet rich in foods of plant origin, including non-starchy fruits and vegetables, non-starchy roots and tubers, and whole grains, may have protective effects against cancer. […] Consumption of coffee is associated with a reduced risk of liver cancer and endometrial cancer. Additionally, a higher coffee intake was shown to be related to a lower risk of melanoma and oral/pharyngeal cancer. However, a higher risk of childhood acute lymphocytic leukemia and bladder cancer actually is associated with higher coffee intake. However, it’s important to note that these claims are associations and there is not strong evidence that validates the effects of coffee consumption and cancer risk.
- #78 Cancer prevention – Wikipediahttps://en.wikipedia.org/wiki/Cancer_prevention
Future preventive screening measures can be additionally improved by minimizing invasiveness and increasing specificity by taking individual biological makeup into account, also known as „population-based personalized cancer screening.” […] Dietary recommendations for reducing cancer risk typically include an emphasis on vegetables, fruit, whole grains, and fish, and an avoidance of processed and red meat (beef, pork, lamb), animal fats, and refined carbohydrates. The World Cancer Research Fund recommends a diet rich in fruits and vegetables to reduce the risk of cancer. A diet rich in foods of plant origin, including non-starchy fruits and vegetables, non-starchy roots and tubers, and whole grains, may have protective effects against cancer. […] Consumption of coffee is associated with a reduced risk of liver cancer and endometrial cancer. Additionally, a higher coffee intake was shown to be related to a lower risk of melanoma and oral/pharyngeal cancer. However, a higher risk of childhood acute lymphocytic leukemia and bladder cancer actually is associated with higher coffee intake. However, it’s important to note that these claims are associations and there is not strong evidence that validates the effects of coffee consumption and cancer risk.
- #79 National Cancer Prevention Month | Cancer Awareness Months | AACRhttps://www.aacr.org/patients-caregivers/awareness-months/national-cancer-prevention-month/
Scientists are investigating new ways to prevent breast cancer, with clinical trials involving vaccines, personalized doses of tamoxifen, and targeted inhibition of the cells that give rise to breast cancer. […] A lack of awareness regarding the fecal immunochemical test (FIT) used to screen for colorectal cancer, the HIV vaccine, and whole-exome sequencing is leading to some groups failing to benefit from these cancer screening and prevention methods. […] The AACR is committed to advancing the science of cancer prevention. […] With its funding partners, the AACR makes grants available to scientists studying prevention of a variety of cancers.
- #80https://www.who.int/activities/preventing-cancer
Between 30-50% of all cancer cases are preventable. Prevention offers the most cost-effective long-term strategy for the control of cancer. WHO works with Member States to strengthen national policies and programmes to raise awareness and, reduce exposure to cancer risk factors, and also ensure that people are provided with the information and support they need to adopt healthy lifestyles. […] Tobacco smoke has more than 7000 chemicals, at least 250 are known to be harmful and at least 69 are known to cause cancer. […] Alcohol, as classified by the International Agency for Research on Cancer, is a toxic, psychoactive, and dependence-producing substance and a Group 1 carcinogen that is causally linked to 7 types of cancer, including oesophagus, liver, colorectal, and breast cancers. […] Overweight and obesity are linked to many types of cancer such as oesophagus, colorectal, breast, endometrial and kidney. Regular physical activity, and maintaining a healthy body weight, and a healthy diet can risk.
- #81https://www.who.int/health-topics/cancer
Between 30% and 50% of cancer deaths could be prevented by modifying or avoiding key risk factors and implementing existing evidence-based prevention strategies. […] The cancer burden can also be reduced through early detection of cancer and management of patients who develop cancer. […] Prevention also offers the most cost-effective long-term strategy for the control of cancer. […] Modifying or avoiding the following key risk factors can help prevent cancer: avoid tobacco use, including cigarettes and smokeless tobacco; maintain a healthy weight; eat a healthy diet with plenty of fruit and vegetables; exercise regularly; limit alcohol use; practice safe sex; get vaccinated against hepatitis B and human papillomavirus (HPV); reduce exposure to ultraviolet radiation; prevent unnecessary ionizing radiation exposure (e.g. minimize occupational exposure, ensure safe and appropriate medical use of radiation in diagnosis and treatment); avoid urban air pollution and indoor smoke from household use of solid fuels; get regular medical care; and some chronic infections are also risk factors for cancer. People in low- and middle-income countries are more likely to develop cancer through chronic infections.
- #82 Therapeutic cancer prevention: achievements and ongoing challenges â a focus on breast and colorectal cancerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6396378/
A metaanalysis of epidemiological studies, including a total of 16 105 cases, showed a 27% risk reduction of CRC with aspirin use. […] As a result of the current clinical evidence, aspirin is gaining acceptance as a colorectal cancer preventive therapy in agestratified groups, as highlighted by the recently updated US Preventive Services Task Force guidelines which recommend aspirin for primary cancer prevention in individuals aged 5059 years, who also have a 10% or greater 10year risk of cardiovascular disease. […] Clinical evidence has convincingly demonstrated that it is possible to lower cancer incidence, at least for breast and colorectal cancer, through the use of preventive medicine. […] Implementing awareness and education on cancer prevention is mandatory for both the general public and healthcare professionals.
- #83 Therapeutic cancer prevention: achievements and ongoing challenges â a focus on breast and colorectal cancerhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6396378/
A metaanalysis of epidemiological studies, including a total of 16 105 cases, showed a 27% risk reduction of CRC with aspirin use. […] As a result of the current clinical evidence, aspirin is gaining acceptance as a colorectal cancer preventive therapy in agestratified groups, as highlighted by the recently updated US Preventive Services Task Force guidelines which recommend aspirin for primary cancer prevention in individuals aged 5059 years, who also have a 10% or greater 10year risk of cardiovascular disease. […] Clinical evidence has convincingly demonstrated that it is possible to lower cancer incidence, at least for breast and colorectal cancer, through the use of preventive medicine. […] Implementing awareness and education on cancer prevention is mandatory for both the general public and healthcare professionals.