Nowotwór
Epidemiologia
Epidemiologia nowotworów zajmuje się analizą rozkładu i czynników ryzyka nowotworów w populacjach, co jest kluczowe dla kontroli zdrowia publicznego. W USA nowotwory stanowią drugą przyczynę zgonów, odpowiadając za 25% zgonów w 2008 roku, z rakiem płuc jako najczęstszą przyczyną (30%). Najczęściej diagnozowanymi nowotworami były rak prostaty u mężczyzn i rak piersi u kobiet (po około 25% nowych przypadków). Przewiduje się, że w 2025 roku w USA zostanie zdiagnozowanych 84 870 nowych przypadków raka pęcherza moczowego, z 17 420 zgonami. W krajach uprzemysłowionych 90% nowotworów pęcherza to raki urotelialne. Nadzór epidemiologiczny, realizowany m.in. przez programy SEER i NPCR, umożliwia systematyczne gromadzenie i analizę danych o zapadalności, leczeniu i przeżywalności, co pozwala na monitorowanie trendów, ocenę skuteczności interwencji oraz identyfikację nierówności zdrowotnych. Rejestry nowotworów, takie jak Cancer Surveillance System i Los Angeles County Cancer Surveillance Program, dostarczają wysokiej jakości danych, z zachowaniem standardów kompletności powyżej 98% dla złośliwych guzów pierwotnych.
- Wprowadzenie do epidemiologii nowotworów
- Nadzór epidemiologiczny nowotworów
- Źródła danych w nadzorze epidemiologicznym nowotworów
- Wykorzystanie danych z nadzoru epidemiologicznego
- Wyzwania i przyszłość nadzoru epidemiologicznego nowotworów
- Nierówności w epidemiologii nowotworów
- Specyficzne programy nadzoru dla wysokiego ryzyka nowotworowego
- Badania nad nowymi modelami nadzoru epidemiologicznego
- Przyszłość epidemiologii nowotworów
- Podsumowanie znaczenia nadzoru epidemiologicznego nowotworów
Wprowadzenie do epidemiologii nowotworów
Epidemiologia nowotworów to dziedzina nauki zajmująca się badaniem rozkładu i determinantów występowania chorób nowotworowych w populacjach oraz wykorzystaniem tej wiedzy do kontroli problemów zdrowotnych. Nowotwór jest drugą wiodącą przyczyną zgonów w Stanach Zjednoczonych i stanowi poważny problem zdrowia publicznego na całym świecie12. W 2008 roku nowotwory były odpowiedzialne za 25% wszystkich zgonów w USA, przy czym 30% z nich stanowił rak płuc. W tym samym roku najczęściej występującym nowotworem u mężczyzn był rak prostaty (około 25% nowych przypadków), a u kobiet rak piersi (również około 25% nowych rozpoznań)3.
Szacuje się, że w roku 2025 w Stanach Zjednoczonych zostanie zdiagnozowanych 84 870 nowych przypadków raka pęcherza moczowego, a 17 420 osób umrze z powodu tej choroby4. Na całym świecie co roku diagnozuje się raka u około 275 000 osób, a około 108 000 umiera z powodu tej choroby5. W krajach uprzemysłowionych 90% nowotworów pęcherza to raki uroteliale6.
Nadzór epidemiologiczny nowotworów
Nadzór epidemiologiczny nowotworów to ciągłe, systematyczne gromadzenie, analiza i interpretacja danych dotyczących nowotworów, niezbędnych do planowania, wdrażania i oceny praktyk zdrowia publicznego7. Jest to podstawowe narzędzie w walce o zmniejszenie obciążenia nowotworami, które pozwala nie tylko śledzić postępy i mierzyć sukcesy, ale także identyfikować problematyczne obszary8.
Znaczenie nadzoru epidemiologicznego
Dane z nadzoru epidemiologicznego nowotworów są kluczowe dla identyfikacji potrzeb, planowania interwencji, kierowania zasobami zdrowia publicznego oraz oceny ogólnej skuteczności inicjatyw mających na celu zapobieganie lub leczenie nowotworów i ich negatywnych konsekwencji zdrowotnych9. Dane te mogą być wykorzystywane do śledzenia trendów w czasie, znajdowania wzorców nowotworów w określonych regionach lub grupach ludzi oraz wykazywania, czy badania przesiewowe i inne środki zapobiegawcze przynoszą efekty10.
Nadzór epidemiologiczny nowotworów pozwala również na identyfikację i śledzenie pojawiających się trendów i nierówności w występowaniu nowotworów i ich wynikach11. Jest to szczególnie ważne w kontekście różnic w obciążeniu wieloma typami nowotworów, które wskazują na istnienie różnych ekspozycji na czynniki rakotwórcze, podkreślając potrzebę kontekstowo specyficznych badań epidemiologicznych nad etiologią nowotworów i lokalną polityką w zakresie profilaktyki i wczesnego wykrywania12.
Programy nadzoru epidemiologicznego
W Stanach Zjednoczonych głównym programem nadzoru epidemiologicznego nowotworów jest Surveillance, Epidemiology, and End Results (SEER) prowadzony przez National Cancer Institute (NCI)13. Program SEER zbiera i publikuje dane dotyczące zapadalności na nowotwory i przeżywalności z rejestrów nowotworów obejmujących około 45,9% populacji Stanów Zjednoczonych14. Jest to jedyne kompleksowe źródło informacji na temat zapadalności na nowotwory i przeżywalności w Stanach Zjednoczonych, które zawiera dane dotyczące stadium nowotworu w momencie diagnozy oraz przeżywalności pacjentów15.
Innym ważnym programem jest National Program of Cancer Registries (NPCR) Centrów Kontroli i Prewencji Chorób (CDC), który wspiera rejestry nowotworów oparte na populacji w departamentach zdrowia stanów16. Razem NPCR i SEER zbierają dane dla całej populacji USA17.
Na poziomie międzynarodowym, Międzynarodowa Agencja Badań nad Rakiem (IARC) prowadzi Global Cancer Observatory, interaktywną platformę internetową przedstawiającą globalne wskaźniki nowotworowe o bezpośrednim znaczeniu dla badań i polityki dotyczącej nowotworów18. IARC koordynuje również Global Initiative for Cancer Registry Development (GICR), która ma na celu znaczne zwiększenie zasięgu, jakości i wykorzystania danych z rejestrów nowotworów opartych na populacji w krajach o niskich i średnich dochodach19.
Źródła danych w nadzorze epidemiologicznym nowotworów
Rejestry nowotworów stanowią fundament programów nadzoru epidemiologicznego nowotworów20. Rejestry te zbierają dane z różnych źródeł, w tym szpitali, gabinetów lekarskich, domów opieki, laboratoriów patologicznych, ambulatoriów, centrów leczenia radioterapią i chemioterapią oraz innych placówek opieki onkologicznej21.
Rejestry nowotworów
Rejestry nowotworów oparte na populacji zbierają informacje o nowych przypadkach nowotworów, stopniu zaawansowania choroby, badaniach przesiewowych, leczeniu, przeżywalności oraz zgonach z powodu nowotworów22. Dane te mogą pokazywać wskaźniki zapadalności (nowych przypadków) i śmiertelności w różnych regionach kraju23.
Przykładem rejestru nowotworowego jest Cancer Surveillance System (CSS) finansowany przez program SEER w Fred Hutchinson Cancer Center. CSS gromadzi wysokiej jakości dane dotyczące zapadalności, leczenia i obserwacji wszystkich nowo zdiagnozowanych nowotworów (z wyjątkiem nieczerniakowych nowotworów skóry) w 13 zachodnich hrabstwach stanu Waszyngton24.
Innym przykładem jest Los Angeles County Cancer Surveillance Program (CSP), który jest rejestrem nowotworów opartym na populacji dla hrabstwa Los Angeles. Od 1972 roku CSP rutynowo zbiera i analizuje informacje o wszystkich nowych diagnozach nowotworów postawionych wśród mieszkańców hrabstwa25.
Jakość danych
Kontrola jakości jest integralną częścią programu SEER od jego powstania26. Standard kompletności dla złośliwych guzów pierwotnych wynosi 98% lub więcej27. Rejestry SEER są wybierane tak, aby reprezentowały grupy demograficzne USA, z nadreprezentacją Afroamerykanów, Latynosów i Azjatów z wysp Pacyfiku28.
W 2022 roku North American Association of Central Cancer Registries (NAACCR) przyznało Michigan Cancer Surveillance Program certyfikat złoty za jakość, kompletność i terminowość danych o nowotworach z 2019 roku29. Program ten został również wyróżniony przez CDC jako Registry of Distinction za dostarczanie wysokiej jakości danych do działań związanych z profilaktyką i kontrolą nowotworów na poziomie lokalnym, regionalnym i krajowym30.
Wykorzystanie danych z nadzoru epidemiologicznego
Dane z nadzoru epidemiologicznego nowotworów są wykorzystywane w różnych celach, od badań naukowych po planowanie zdrowia publicznego i podejmowanie decyzji politycznych31.
Badania naukowe
Baza danych SEER może być wykorzystywana w badaniach obserwacyjnych i krajowych oraz lokalnych programach zdrowia publicznego, które mogą promować zdrowie poprzez zapobieganie i kontrolę chorób32. Ponad 17 000 artykułów opublikowanych w latach 1973-2020 wykorzystywało bazę danych SEER jako główne źródło danych, a ponad 86 000 artykułów odwoływało się do SEER w swoich badaniach33.
SEER rejestruje informacje o około 400 000 przypadkach nowotworów rocznie, a ilość danych SEER szybko rośnie34. Efektywne wykorzystanie bazy danych SEER do badań nad nowotworami zależy od odpowiedniego zastosowania projektów badań i modeli statystycznych35.
Informowanie o polityce zdrowotnej
Dane z nadzoru epidemiologicznego nowotworów są wykorzystywane do informowania o priorytetach globalnych, regionalnych i krajowych dla działań w zakresie kontroli nowotworów36. Dostarczają one decydentom politycznym dowodów dotyczących międzynarodowych różnic w obciążeniu wieloma typami nowotworów, wskazując na potrzebę badań epidemiologicznych specyficznych dla danego kontekstu nad etiologią nowotworów oraz lokalnej polityki w zakresie profilaktyki i wczesnego wykrywania37.
Amerykańskie Towarzystwo Raka (ACS) co roku publikuje raport Cancer Facts & Figures wraz z towarzyszącym mu artykułem Cancer Statistics, publikowanym w czasopiśmie naukowym ACS CA: A Cancer Journal for Clinicians38. Te szeroko cytowane raporty przedstawiają najbardziej aktualne wskaźniki i trendy w zapadalności na nowotwory, śmiertelności i przeżywalności, a także najbardziej aktualne informacje na temat objawów, profilaktyki, wczesnego wykrywania i leczenia39.
Planowanie działań w zakresie zdrowia publicznego
Informacje z rejestrów nowotworów pomagają w kierowaniu programami profilaktyki i kontroli nowotworów, które koncentrują się na zmianie określonych zachowań (takich jak palenie) i ograniczaniu innych zagrożeń środowiskowych40. Analizy epidemiologiczne nowotworów wykazały trend spadkowy w częstości występowania nowotworów wśród starszych populacji; jednak pojawia się alarmujący wzrost zachorowań na nowotwory wśród młodszych dorosłych (w wieku poniżej 50 lat)41.
Identyfikacja proporcji nowotworów, którym można zapobiec, lub części zgonów związanych z nowotworami, których można uniknąć dzięki wczesnym wysiłkom wykrywania, może wzmocnić kampanie profilaktyczne i zwiększające świadomość42. Na przykład, europejski kodeks przeciwko nowotworom od lat upraszcza wyniki badań epidemiologicznych dotyczących czynników ryzyka, tak aby można było podejmować indywidualne działania pomagające zapobiegać nowotworom43. Kampania ta została oparta na fakcie, że 40% przypadków nowotworów można zapobiec, a kolejnym 40% zgonów związanych z nowotworami można zapobiec, jeśli nowotwór zostanie wykryty wcześniej44.
Wyzwania i przyszłość nadzoru epidemiologicznego nowotworów
Mimo postępów w nadzorze epidemiologicznym nowotworów, nadal istnieją wyzwania, które wymagają rozwiązania45.
Wyzwania
Wyzwania związane z obecnym podejściem do nadzoru epidemiologicznego nowotworów w Stanach Zjednoczonych obejmują opóźnienia i luki w zbieraniu danych, a także nieodpowiednią infrastrukturę i siłę roboczą, aby nadążyć za postępami w informatyce i leczeniu nowotworów46.
Inne wyzwania obejmują możliwe konsekwencje postępów w informatyce, leczeniu nowotworów i badaniach, które szybko wyprzedzają infrastrukturę i metodologię nadzoru epidemiologicznego nowotworów, w tym wyzwania związane z terminową oceną jakości opieki onkologicznej i potencjał do pogłębiania różnic w opiece onkologicznej i wynikach pacjentów47.
Potencjalne kierunki rozwoju
Potencjalne strategie poprawy wysiłków w zakresie nadzoru epidemiologicznego nowotworów obejmują współpracę interdyscyplinarną i wnioski wyciągnięte z innych systemów nadzoru48. Istnieją również potencjalne możliwości modernizacji nadzoru epidemiologicznego nowotworów poprzez odpowiednie wykorzystanie technologii, takich jak systemy elektronicznych kart zdrowia, sztuczna inteligencja, gromadzenie danych w chmurze i powiązania danych49.
Przyszłe kierunki dla rejestrów nowotworów obejmują wspieranie większej elektronicznej wymiany informacji50. Nadzór epidemiologiczny nowotworów koncentruje się na identyfikacji i ocenie, w jaki sposób wykorzystać powstające technologie do włączenia zautomatyzowanych procesów i elektronicznej wymiany danych51. Projekty te oceniają strumienie danych, takie jak dane z roszczeń ubezpieczeniowych, które mogą spełniać wymagania rejestrów nowotworów, eliminując potrzebę tworzenia specjalnych strumieni danych dla rejestrów nowotworów52.
Nierówności w epidemiologii nowotworów
Epidemiologia nowotworów odgrywa kluczową rolę w identyfikacji i eliminacji nierówności w zakresie nowotworów53.
Identyfikacja nierówności
IARC zwołała warsztaty ekspertów z naukowców z różnych dyscyplin w celu określenia priorytetów badawczych dla zmniejszenia nierówności społecznych w zakresie nowotworów, co doprowadziło do powstania publikacji naukowej IARC nr 16854. Na tej podstawie w ramach CSU opracowano kilka projektów badawczych dotyczących nierówności społecznych i nowotworów, w tym dokumentację nierówności społecznych w zakresie nowotworów między krajami i w ich obrębie, ze szczególnym uwzględnieniem gradientu związku, a także zmian czasowych i geograficznych55.
Zespół ds. Nierówności w Nowotworach IARC (CIN), kierowany przez CSU, dąży do pomiaru, zrozumienia i zmniejszenia nierówności społecznych w zakresie nowotworów56. Celem CSU jest lepsze zrozumienie obciążenia ekonomicznego nowotworami dla gospodarek narodowych i systemów opieki zdrowotnej, a także dla osób i gospodarstw domowych57.
Strategie eliminacji nierówności
Deskryptywna epidemiologia nierówności społecznych w zakresie nowotworów obejmuje opracowanie ram badawczych i danych do badania nierówności społeczno-ekonomicznych w zakresie nowotworów, włączenie wskaźników do europejskiego rejestru nierówności w nowotworach oraz ocenę nierówności w umieralności na nowotwory według wykształcenia, płci, wieku i miejsca zamieszkania58.
Dr Tomi Akinyemiju, profesor w Department of Population Health Sciences, uważa, że epidemiolodzy mają zawodowy i moralny obowiązek zapewnienia, że rozwiązania medyczne i polityczne są stosowane sprawiedliwie we wszystkich populacjach59. Według niej przyszłość epidemiologii musi uwzględniać, że zagrożenia zdrowotne nie są równomiernie rozłożone. Pewne społeczności są bardziej narażone na zagrożenia zdrowotne, takie jak ekspozycja na toksyczne odpady, lub są bardziej dotknięte zmianami klimatu lub infekcjami, jak widzieliśmy w przypadku COVID-1960.
Specyficzne programy nadzoru dla wysokiego ryzyka nowotworowego
Dla osób o zwiększonym ryzyku zachorowania na nowotwory istnieją specjalne programy nadzoru61.
Programy nadzoru dla osób o wysokim ryzyku
W klinice Overlake High-Risk Cancer Surveillance istnieje zobowiązanie do zapewnienia specjalistycznej opieki osobom o podwyższonym ryzyku zachorowania na nowotwory62. Misją kliniki jest wspieranie osób z wysoką rodzinną lub genetyczną predyspozycją do nowotworów poprzez oferowanie kompleksowej oceny ryzyka, badań genetycznych, poradnictwa i proaktywnych planów opieki63.
Jeśli osoba jest narażona na zwiększone ryzyko zachorowania na nowotwory, korzystanie z dodatkowych opcji badań przesiewowych może wykryć nowotwór na wcześniejszym etapie lub zmniejszyć ryzyko jego rozwoju64. Nadzór i profilaktyka są niezbędne dla każdego, kto jest narażony na wyższe ryzyko dziedzicznych nowotworów, w tym piersi, jajników, żołądka, jelita grubego, trzustki, czerniaka, endometrium i prostaty65.
Nadzór aktywny
Nadzór aktywny to forma leczenia raka, szczególnie korzystna dla mężczyzn z rakiem prostaty niskiego ryzyka6667. W ramach nadzoru aktywnego pacjent jest monitorowany co kilka miesięcy, aby sprawdzić, czy nie ma zmian w prostacie68. Badania pokazują, że nadzór aktywny jest bezpiecznym leczeniem dla osób z nowotworami niskiego ryzyka69.
Nadzór aktywny pozwala wielu pacjentom prowadzić normalne życie, podczas gdy specjaliści uważnie śledzą postęp ich nowotworów70. Ponieważ nadzór aktywny pozwala monitorować nowotwór od początku, eksperci mogą stale analizować skutki i postęp choroby, aby określić następne kroki, zanim objawy się pogorszą71.
Badania nad nowymi modelami nadzoru epidemiologicznego
Naukowcy nieustannie poszukują nowych modeli i podejść do nadzoru epidemiologicznego nowotworów72.
Nowe kierunki badań
CSU jest zaangażowany w wiele badań współpracujących mających na celu opisanie i interpretację zmieniającej się wielkości i charakteru profili nowotworowych na całym świecie, poprzez obserwację zmian geograficznych i w czasie73. Badania te mają na celu:
- Pogłębienie zrozumienia globalnych, regionalnych, krajowych i subkrajowych zmian w ryzyku zachorowania na raka i przeżywalności oraz ich determinantów, w tym w odniesieniu do trwających przemian społeczno-gospodarczych i nierówności społecznych74
- Generowanie dowodów naukowych związanych ze skutecznością wdrażania interwencji w zakresie profilaktyki pierwotnej, w tym zapobiegania lub ograniczania narażenia na ustalone modyfikowalne czynniki ryzyka75
- Pogłębienie zrozumienia ekonomicznych skutków nowotworów, aby zapewnić sprawiedliwe i zrównoważone systemy opieki zdrowotnej, które są w stanie skutecznie zmniejszyć obciążenie nowotworami76
Innowacyjne podejścia
CSU planuje przeprowadzić dogłębne monitorowanie kluczowych wskaźników zapadalności na nowotwory, przeżywalności i umieralności w trakcie i po przyszłych kryzysach związanych z pandemiami lub innymi poważnymi wydarzeniami77. Planuje również zbadać przyczyny zakłóceń w usługach onkologicznych i skuteczne strategie łagodzenia78.
CSU chce również zapewnić narzędzie do modelowania krótko-, średnio- i długoterminowego wpływu zakłóceń na wyniki nowotworowe, aby poprawić odporność w kontroli nowotworów79. Inne innowacyjne podejścia obejmują:
- Badania ilościowe określające odsetek przypadków nowotworów, które można przypisać czynnikom ryzyka (aktualizacje lub nowe czynniki: wskaźnik masy ciała, palenie, w tym używanie tytoniu bezdymnego, brak aktywności fizycznej, czynniki zakaźne i promieniowanie ultrafioletowe)80
- Szacowanie obciążenia nowotworami przy użyciu lat życia skorygowanych o niepełnosprawność (DALY)81
- Modele dynamiczne do przewidywania długoterminowego przyszłego obciążenia w scenariuszach wdrażania programów badań przesiewowych i szczepień82
Przyszłość epidemiologii nowotworów
Przyszłość epidemiologii nowotworów leży w bardziej spersonalizowanych podejściach dostosowanych do unikalnego kontekstu każdej osoby83. W zakresie przewidywania ryzyka, przyszłość epidemiologii polega na wykorzystaniu dużych zbiorów danych i narzędzi takich jak sztuczna inteligencja i uczenie maszynowe do złożonych analiz milionów punktów danych84.
Jednak nawet kiedy mamy interwencje, które działają doskonale, musimy upewnić się, że istnieje równy dostęp do tej wiedzy i wglądu. W Stanach Zjednoczonych równość zdrowotna pozostaje problemem85.
Przyszłość epidemiologii musi uwzględniać, że zagrożenia zdrowotne nie są równomiernie rozłożone. Pewne społeczności są bardziej narażone na zagrożenia zdrowotne, takie jak ekspozycja na toksyczne odpady, lub są bardziej dotknięte zmianami klimatu lub infekcjami, jak widzieliśmy w przypadku COVID-1986.
Podsumowanie znaczenia nadzoru epidemiologicznego nowotworów
Nadzór epidemiologiczny nowotworów ma kluczowe znaczenie dla zmniejszenia obciążenia nowotworami w populacji87. W ciągu ostatnich 70 lat epidemiologia odegrała kluczową rolę w opisaniu obciążenia nowotworami, identyfikacji wielu czynników ryzyka i ocenie wyników opieki88.
Dowody generowane z badań epidemiologicznych pokazują, że około 40% wszystkich przypadków nowotworów można zapobiec, a dalszym powiązanym zgonom można zapobiec poprzez wczesne wykrywanie i badania przesiewowe89.
Istotnym aspektem epidemiologii jest monitorowanie wielkości i trendów występowania nowotworów poprzez rejestry nowotworów oparte na populacji, co umożliwia alokację przyszłych inicjatyw w zakresie profilaktyki i wczesnego wykrywania, a także wsparcie obiektów i planowanie siły roboczej90.
Kontynuacja i rozwój programów nadzoru epidemiologicznego nowotworów jest niezbędna do skutecznego zmniejszenia obciążenia nowotworami w populacji i poprawy wyników zdrowotnych dla wszystkich91.
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Materiały źródłowe
- #1 Epidemiology of cancer – Wikipediahttps://en.wikipedia.org/wiki/Epidemiology_of_cancer
In 2008, cancer was responsible for 25% of all US deaths, with 30% of these from lung cancer. In 2008, the most commonly occurring cancer in men was prostate cancer, at about 25% of new cases. In 2008, amongst women, breast cancer was the most commonly occurring cancer, with about 25% of cancer diagnoses. […] In 2003, in the developed world, one in three people developed cancer during their lifetimes. If all cancer patients survived and cancer occurred randomly, the normal lifetime odds of developing a second primary cancer (not the first cancer spreading to a new site) would be one in nine. However, cancer survivors have an increased risk of developing a second primary cancer, and the odds in 2003 were about one in 4.5.
- #2 Cancer Population Science | Herbert Irving Comprehensive Cancer Center (HICCC) – New Yorkhttps://www.cancer.columbia.edu/research/programs/cancer-population-science
Aimed at reducing the burden from cancer on a population level, the Cancer Population Science (CPS) Program is conducting observational and interventional studies that focus on primary prevention, early detection, health outcomes and the delivery of cancer care to diverse communities. […] Cancer is a major burden on society in the United States and across the world. In 2018, an estimated 1.7 million new cases of cancer will be diagnosed in the United States over 600,000 people will die from the disease. […] According to the National Cancer Institute, the estimated national expenditures for cancer care in the United States in 2017 were $147.3 billion and costs are likely to increase. […] While cancer affects all population groups, the disease may have a larger or more severe impact on some groups over others, and understanding and addressing these health disparities remains crucial.
- #3 Epidemiology of cancer – Wikipediahttps://en.wikipedia.org/wiki/Epidemiology_of_cancer
In 2008, cancer was responsible for 25% of all US deaths, with 30% of these from lung cancer. In 2008, the most commonly occurring cancer in men was prostate cancer, at about 25% of new cases. In 2008, amongst women, breast cancer was the most commonly occurring cancer, with about 25% of cancer diagnoses. […] In 2003, in the developed world, one in three people developed cancer during their lifetimes. If all cancer patients survived and cancer occurred randomly, the normal lifetime odds of developing a second primary cancer (not the first cancer spreading to a new site) would be one in nine. However, cancer survivors have an increased risk of developing a second primary cancer, and the odds in 2003 were about one in 4.5.
- #4 Bladder Cancer: Practice Essentials, Background, Anatomyhttps://emedicine.medscape.com/article/458825-overview
The American Cancer Society estimates that 84,870 new cases of bladder cancer will be diagnosed in the United States in 2025 and that 17,420 people will die of the disease. The incidence of bladder cancer increases with age, with the median age at diagnosis being 73 years; bladder cancer is rarely diagnosed before age 40 years. Bladder cancer is about 4 times more common in men than in women. The male predominance in bladder cancer in the United States reflects the prevalence of urothelial carcinoma (transitional cell carcinoma). With small cell carcinoma in contrast to urothelial carcinoma the male-to-female incidence ratio is 1:2. […] Worldwide, bladder cancer is diagnosed in approximately 275,000 people each year, and about 108,000 die of this disease. In industrialized countries, 90% of bladder cancers are urothelial carcinomas. In developing countries particularly in the Middle East and Africa the majority of bladder cancers are SCCs, and most of these cancers are secondary to Schistosoma haematobium infection. Urothelial carcinoma is reported to be the most common urologic cancer in China.
- #5 Bladder Cancer: Practice Essentials, Background, Anatomyhttps://emedicine.medscape.com/article/458825-overview
The American Cancer Society estimates that 84,870 new cases of bladder cancer will be diagnosed in the United States in 2025 and that 17,420 people will die of the disease. The incidence of bladder cancer increases with age, with the median age at diagnosis being 73 years; bladder cancer is rarely diagnosed before age 40 years. Bladder cancer is about 4 times more common in men than in women. The male predominance in bladder cancer in the United States reflects the prevalence of urothelial carcinoma (transitional cell carcinoma). With small cell carcinoma in contrast to urothelial carcinoma the male-to-female incidence ratio is 1:2. […] Worldwide, bladder cancer is diagnosed in approximately 275,000 people each year, and about 108,000 die of this disease. In industrialized countries, 90% of bladder cancers are urothelial carcinomas. In developing countries particularly in the Middle East and Africa the majority of bladder cancers are SCCs, and most of these cancers are secondary to Schistosoma haematobium infection. Urothelial carcinoma is reported to be the most common urologic cancer in China.
- #6 Bladder Cancer: Practice Essentials, Background, Anatomyhttps://emedicine.medscape.com/article/458825-overview
The American Cancer Society estimates that 84,870 new cases of bladder cancer will be diagnosed in the United States in 2025 and that 17,420 people will die of the disease. The incidence of bladder cancer increases with age, with the median age at diagnosis being 73 years; bladder cancer is rarely diagnosed before age 40 years. Bladder cancer is about 4 times more common in men than in women. The male predominance in bladder cancer in the United States reflects the prevalence of urothelial carcinoma (transitional cell carcinoma). With small cell carcinoma in contrast to urothelial carcinoma the male-to-female incidence ratio is 1:2. […] Worldwide, bladder cancer is diagnosed in approximately 275,000 people each year, and about 108,000 die of this disease. In industrialized countries, 90% of bladder cancers are urothelial carcinomas. In developing countries particularly in the Middle East and Africa the majority of bladder cancers are SCCs, and most of these cancers are secondary to Schistosoma haematobium infection. Urothelial carcinoma is reported to be the most common urologic cancer in China.
- #7 CDC’s Public Health Surveillance of Cancerhttps://www.cdc.gov/pcd/issues/2017/16_0480.htm
Routine data collection efforts are a necessary, often underappreciated, component of nearly all cancer research and prevention efforts. Public health cancer surveillance data are crucial for identifying needs, planning interventions, directing public health resources, and evaluating the overall effectiveness of initiatives aimed at preventing or treating cancer and its negative health consequences. […] Cancer is the second leading cause of death in the United States and therefore a focus of public health efforts. One defining feature of the public health approach to cancer control is its reliance on population data for planning and evaluating efforts aimed at preventing the health consequences of cancer. […] The World Health Organization defines public health surveillance as the continuous, systematic collection, analysis, and interpretation of health-related data needed for the planning, implementation, and evaluation of public health practice.
- #8 Cancer Surveillance Opportunities to Meet Prevention and Control Challengeshttps://pmc.ncbi.nlm.nih.gov/articles/PMC8634486/
News from the latest Annual Report to the Nation of the Status of Cancer by Islami et al. (1) is largely positive. Cancer mortality overall continues to decrease; for most cancers, incidence is also decreasing. […] Cancer surveillance programs, giving rise to the data in this annual report jointly issued by the Centers for Disease Control and Prevention, the North American Association of Central Cancer Registries, the American Cancer Society, and the National Cancer Institute, are unique in their truly universal, population-based coverage. […] Cancer surveillance is a fundamental tool in our battle to reduce the burden of cancer. The annual reports allow us not only to track progress and measure successes but also to identify problem areas. Being responsive to these identified areas of interest would enable surveillance programs to further meet the needs of all those interested in cancer prevention and control, including clinicians, public health program developers, researchers, and policy makers.
- #9 CDC’s Public Health Surveillance of Cancerhttps://www.cdc.gov/pcd/issues/2017/16_0480.htm
Routine data collection efforts are a necessary, often underappreciated, component of nearly all cancer research and prevention efforts. Public health cancer surveillance data are crucial for identifying needs, planning interventions, directing public health resources, and evaluating the overall effectiveness of initiatives aimed at preventing or treating cancer and its negative health consequences. […] Cancer is the second leading cause of death in the United States and therefore a focus of public health efforts. One defining feature of the public health approach to cancer control is its reliance on population data for planning and evaluating efforts aimed at preventing the health consequences of cancer. […] The World Health Organization defines public health surveillance as the continuous, systematic collection, analysis, and interpretation of health-related data needed for the planning, implementation, and evaluation of public health practice.
- #10 Cancer Surveillance Programs and Registries in the United States | American Cancer Societyhttps://www.cancer.org/cancer/managing-cancer/making-treatment-decisions/clinical-trials/cancer-surveillance-programs-and-registries-in-the-united-states.html
Cancer surveillance is the ongoing, timely, and systematic collection and analysis of information on new cancer cases, extent of disease, screening tests, treatment, survival, and cancer deaths. […] This cancer information (data) can be used to look for trends over time, to find cancer patterns in certain regions or groups of people, and/or to show whether screening and other prevention measures are making a difference. […] Registries and surveillance information are key parts of cancer prevention and control efforts. […] No single surveillance program in the United States collects data on all cancers diagnosed each year. […] These programs are built on a foundation of existing cancer registries or registries that are set up throughout the country to record and report cancer cases in the areas they cover.
- #11 Cancer Surveillance and Health Services Research (SHSR) | American Cancer Societyhttps://www.cancer.org/research/surveillance-and-health-equity-science/surveillance-research.html
Identify and track emerging trends and inequalities in cancer occurrence and outcomes. […] Contribute to the advancement of surveillance research through scientific publications, conference participation, and collaborations across institutions and disciplines. […] Each year, we produce the ACS flagship report, Cancer Facts Figures, along with its companion article, Cancer Statistics, published in the ACS scientific journal CA: A Cancer Journal for Clinicians. […] These widely cited reports present the most current rates and trends in cancer incidence, mortality, and survival, as well as the most up-to-date information on symptoms, prevention, early detection, and treatment. […] The Surveillance team analyzes and interprets data to produce the ACS Facts Figures. Find the latest information including the most current trends in cancer occurrence survival, as well as information on prevention, early detection, treatment. […] Our team’s epidemiologists regularly update multiple Cancer Facts Figures reports and an interactive statistics website. We also publish additional cancer surveillance research, and we provide statistical support internally and externally.
- #12 How epidemiology can help cancer control efforts and influence policy decisions | UICChttps://www.uicc.org/news-and-updates/blog/how-epidemiology-can-help-cancer-control-efforts-and-influence-policy
The magnitude of cancer, for example, varies between countries in terms of types and rates, according to the latest estimates from the International Agency for Research on Cancer (IARC). These international variations in the burden of many cancer types indicate the existence of different carcinogen exposures, highlighting the need for context-specific epidemiological research on cancer aetiology and local policy for prevention and early detection. […] Furthermore, cancer epidemiological analysis has shown a downward trend in cancer rates among older populations; however, an alarming increase in cancer rates among younger adults (aged 50 years) is emerging. […] Identifying the proportion of cancer that can be prevented or the fraction of cancer-related deaths that might be averted due to early detection efforts can empower prevention and awareness campaigns.
- #13 Surveillance, Epidemiology, and End Results – Wikipediahttps://en.wikipedia.org/wiki/Surveillance,_Epidemiology,_and_End_Results
The Surveillance, Epidemiology, and End Results (SEER) program of the National Cancer Institute (NCI) is a source of epidemiologic information on the incidence and survival rates of cancer in the United States. […] SEER collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 45.9% of the population of the United States. […] The SEER Program is the only comprehensive source of population-based information in the United States that includes stage of cancer at the time of diagnosis and patient survival data. […] National Cancer Institute funds for the program are combined with funding from the Centers for Disease Control and Prevention (CDC) through the National Program of Cancer Registries and with funding from the involved states. […] Quality control has been an integral part of SEER since its inception.
- #14 Surveillance, Epidemiology, and End Results – Wikipediahttps://en.wikipedia.org/wiki/Surveillance,_Epidemiology,_and_End_Results
The Surveillance, Epidemiology, and End Results (SEER) program of the National Cancer Institute (NCI) is a source of epidemiologic information on the incidence and survival rates of cancer in the United States. […] SEER collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 45.9% of the population of the United States. […] The SEER Program is the only comprehensive source of population-based information in the United States that includes stage of cancer at the time of diagnosis and patient survival data. […] National Cancer Institute funds for the program are combined with funding from the Centers for Disease Control and Prevention (CDC) through the National Program of Cancer Registries and with funding from the involved states. […] Quality control has been an integral part of SEER since its inception.
- #15 Surveillance, Epidemiology, and End Results – Wikipediahttps://en.wikipedia.org/wiki/Surveillance,_Epidemiology,_and_End_Results
The Surveillance, Epidemiology, and End Results (SEER) program of the National Cancer Institute (NCI) is a source of epidemiologic information on the incidence and survival rates of cancer in the United States. […] SEER collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 45.9% of the population of the United States. […] The SEER Program is the only comprehensive source of population-based information in the United States that includes stage of cancer at the time of diagnosis and patient survival data. […] National Cancer Institute funds for the program are combined with funding from the Centers for Disease Control and Prevention (CDC) through the National Program of Cancer Registries and with funding from the involved states. […] Quality control has been an integral part of SEER since its inception.
- #16 Cancer Surveillance Programs and Registries in the United States | American Cancer Societyhttps://www.cancer.org/cancer/managing-cancer/making-treatment-decisions/clinical-trials/cancer-surveillance-programs-and-registries-in-the-united-states.html
The NCI contracts with non-profit organizations to collect data on new cancer diagnoses in the designated geographic locations. […] The National Program of Cancer Registries (NPCR) of the Center for Disease Control and Prevention (CDC) supports population-based registries in state health departments. […] State cancer registries are computerized and have many public health uses. […] Together, the NPCR and the National Cancer Institutes SEER Program collect data for the entire US population. […] Future directions for cancer registries include support of more electronic information sharing.
- #17 Cancer Surveillance Programs and Registries in the United States | American Cancer Societyhttps://www.cancer.org/cancer/managing-cancer/making-treatment-decisions/clinical-trials/cancer-surveillance-programs-and-registries-in-the-united-states.html
The NCI contracts with non-profit organizations to collect data on new cancer diagnoses in the designated geographic locations. […] The National Program of Cancer Registries (NPCR) of the Center for Disease Control and Prevention (CDC) supports population-based registries in state health departments. […] State cancer registries are computerized and have many public health uses. […] Together, the NPCR and the National Cancer Institutes SEER Program collect data for the entire US population. […] Future directions for cancer registries include support of more electronic information sharing.
- #18 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu/
CSU compiles, estimates, and reports cancer statistics through its flagship projects and databases and through high-impact peer-reviewed publications. The Global Cancer Observatory is an interactive web-based platform that presents global cancer indicators of direct relevance to cancer research and policy, developed via CSUs descriptive research programme. […] CSU has several major lines of research based on the databases held within CSU, including in-depth assessments of the international variations for specific cancer types, quantification of the major risk factors contributing to the current cancer burden worldwide, and a global assessment of the long-term benefits of preventive interventions. […] The International Incidence of Childhood Cancer (IICC) series is a flagship project of CSU, undertaken in collaboration with the IACR, that produces quality-assured incidence data on cancer in children and adolescents, based on collaborations with paediatric and general cancer registries worldwide. CSUs surveillance and research work is increasingly embedded within the GICR programme and linked to the continuing efforts of the WHO Global Initiative for Childhood Cancer.
- #19 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu/
CSU informs global, regional, and national priorities for cancer control action via dedicated programmes of work in six complementary areas. […] CSU provides the Secretariat for the International Association of Cancer Registries (IACR), the professional society dedicated to fostering the aims and activities of cancer registries worldwide. This direct link to registries remains vital to CSUs remit of expanding the availability of quality-assured cancer data. The joint IARCIACR Cancer Incidence in Five Continents series is a flagship publication that compiles comparable cancer incidence rates across diverse registry populations worldwide. […] The Global Initiative for Cancer Registry Development (GICR) aims to markedly increase the coverage, quality, and use of data from PBCRs in low- and middle-income countries. Coordinated by IARC, the GICR brings together major international and national agencies committed to working collaboratively to improve cancer surveillance worldwide.
- #20 Cancer Surveillance Programs and Registries in the United States | American Cancer Societyhttps://www.cancer.org/cancer/managing-cancer/making-treatment-decisions/clinical-trials/cancer-surveillance-programs-and-registries-in-the-united-states.html
Cancer surveillance is the ongoing, timely, and systematic collection and analysis of information on new cancer cases, extent of disease, screening tests, treatment, survival, and cancer deaths. […] This cancer information (data) can be used to look for trends over time, to find cancer patterns in certain regions or groups of people, and/or to show whether screening and other prevention measures are making a difference. […] Registries and surveillance information are key parts of cancer prevention and control efforts. […] No single surveillance program in the United States collects data on all cancers diagnosed each year. […] These programs are built on a foundation of existing cancer registries or registries that are set up throughout the country to record and report cancer cases in the areas they cover.
- #21 Cancer Surveillance Programs and Registries in the United States | American Cancer Societyhttps://www.cancer.org/cancer/managing-cancer/making-treatment-decisions/clinical-trials/cancer-surveillance-programs-and-registries-in-the-united-states.html
Population-based registries in cities and states collect and pull together information from multiple reporting facilities within their geographic regions that can include: Hospitals, Doctors offices, Nursing homes, Pathology laboratories, Ambulatory care facilities or clinics, Radiation and chemotherapy treatment centers, Other cancer care facilities. […] These registries provide data that can show things like new cancer cases (incidence) and death rates (mortality) across regions of the country. […] Information from cancer registries helps guide cancer prevention and control programs that are focused on changing certain behaviors (like smoking) and reducing other environmental risks. […] The National Cancer Data Base (NCDB) is a joint program of hospital registries of the Commission on Cancer (COC) and the American Cancer Society.
- #22 Cancer Surveillance Programs and Registries in the United States | American Cancer Societyhttps://www.cancer.org/cancer/managing-cancer/making-treatment-decisions/clinical-trials/cancer-surveillance-programs-and-registries-in-the-united-states.html
Cancer surveillance is the ongoing, timely, and systematic collection and analysis of information on new cancer cases, extent of disease, screening tests, treatment, survival, and cancer deaths. […] This cancer information (data) can be used to look for trends over time, to find cancer patterns in certain regions or groups of people, and/or to show whether screening and other prevention measures are making a difference. […] Registries and surveillance information are key parts of cancer prevention and control efforts. […] No single surveillance program in the United States collects data on all cancers diagnosed each year. […] These programs are built on a foundation of existing cancer registries or registries that are set up throughout the country to record and report cancer cases in the areas they cover.
- #23 Cancer Surveillance Programs and Registries in the United States | American Cancer Societyhttps://www.cancer.org/cancer/managing-cancer/making-treatment-decisions/clinical-trials/cancer-surveillance-programs-and-registries-in-the-united-states.html
Population-based registries in cities and states collect and pull together information from multiple reporting facilities within their geographic regions that can include: Hospitals, Doctors offices, Nursing homes, Pathology laboratories, Ambulatory care facilities or clinics, Radiation and chemotherapy treatment centers, Other cancer care facilities. […] These registries provide data that can show things like new cancer cases (incidence) and death rates (mortality) across regions of the country. […] Information from cancer registries helps guide cancer prevention and control programs that are focused on changing certain behaviors (like smoking) and reducing other environmental risks. […] The National Cancer Data Base (NCDB) is a joint program of hospital registries of the Commission on Cancer (COC) and the American Cancer Society.
- #24 Cancer Surveillance System (CSS) | Fred Hutchinson Cancer Centerhttps://www.fredhutch.org/en/research/divisions/public-health-sciences-division/research/epidemiology/cancer-surveillance-system.html
In 1974, the U.S. National Cancer Institute’s Surveillance, Epidemiology and End Results (SEER) program funded the Fred Hutch to establish the Cancer Surveillance System (CSS). Our mission is to provide high quality data on the incidence, treatment and follow-up of all newly-diagnosed cancers (except non-melanoma skin cancers) in 13 western Washington State counties. […] The collected data helps public health scientists and practitioners: Track trends in the incidence of all forms of cancer (surveillance) […] Identify and investigate patterns of cancer occurrence (epidemiology) […] Monitor trends in mortality and survival for specific cancers (end results). […] The Surveillance, Epidemiology and End Results (SEER) program has been a trusted source for high quality data since 1973. It currently monitors cancer incidence and survival in approximately 34% of the U.S. population.
- #25 Cancer Surveillance Programhttps://csp.usc.edu/
The Los Angeles Cancer Surveillance Programs mission is to reduce the burden of cancer through monitoring and identifying cancer disparities through innovation and support to the California Cancer Registry and global cancer community and to deliver high quality complete and robust data to reduce morbidity and mortality while improving cancer care in all populations. […] The Los Angeles County Cancer Surveillance Program (CSP) is the population-based cancer registry for Los Angeles County. Since 1972, the CSP has routinely collected and analyzed information on all new cancer diagnoses made among residents of the County. The CSP is a member of the statewide population-based cancer surveillance system, the California Cancer Registry (CCR). It is also part of the National Cancer Institute-funded Surveillance, Epidemiology, and End Results SEER program. The CSP is administered by the University of Southern California (USC) Keck School of Medicine and the USC/Norris Comprehensive Cancer Center. With the large and diverse population of Los Angeles County, the CSP has served as a resource for many epidemiological studies of cancer in Los Angeles County.
- #26 Surveillance, Epidemiology, and End Results – Wikipediahttps://en.wikipedia.org/wiki/Surveillance,_Epidemiology,_and_End_Results
The Surveillance, Epidemiology, and End Results (SEER) program of the National Cancer Institute (NCI) is a source of epidemiologic information on the incidence and survival rates of cancer in the United States. […] SEER collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 45.9% of the population of the United States. […] The SEER Program is the only comprehensive source of population-based information in the United States that includes stage of cancer at the time of diagnosis and patient survival data. […] National Cancer Institute funds for the program are combined with funding from the Centers for Disease Control and Prevention (CDC) through the National Program of Cancer Registries and with funding from the involved states. […] Quality control has been an integral part of SEER since its inception.
- #27 Surveillance, Epidemiology, and End Results Program (SEER) – Healthy People 2030 | odphp.health.govhttps://odphp.health.gov/healthypeople/objectives-and-data/data-sources-and-methods/data-sources/surveillance-epidemiology-and-end-results-program-seer
Surveillance, Epidemiology, and End Results Program (SEER) tracks the incidence of persons diagnosed with cancer during the year and collects follow-up information on all previously diagnosed patients until their death. […] SEER registries cover 36.7 percent of the U.S. Population. […] The completeness standard for malignant primary tumors is 98 percent or greater. […] Not all states are represented. Only certain metropolitan areas are represented. SEER registries are selected to represent US demographic groups, with oversampling for African Americans, Hispanic, and Asian Pacific Islanders.
- #28 Surveillance, Epidemiology, and End Results Program (SEER) – Healthy People 2030 | odphp.health.govhttps://odphp.health.gov/healthypeople/objectives-and-data/data-sources-and-methods/data-sources/surveillance-epidemiology-and-end-results-program-seer
Surveillance, Epidemiology, and End Results Program (SEER) tracks the incidence of persons diagnosed with cancer during the year and collects follow-up information on all previously diagnosed patients until their death. […] SEER registries cover 36.7 percent of the U.S. Population. […] The completeness standard for malignant primary tumors is 98 percent or greater. […] Not all states are represented. Only certain metropolitan areas are represented. SEER registries are selected to represent US demographic groups, with oversampling for African Americans, Hispanic, and Asian Pacific Islanders.
- #29 Michigan Cancer Surveillance Programhttps://www.michigan.gov/mdhhs/doing-business/providers/forms/michigan-cancer-surveillance-program
In 2022, the North American Association of Central Cancer Registries (NAACCR) awarded Gold Certification to the Michigan Cancer Surveillance Program for quality, completeness, and timeliness of 2019 cancer data. […] We are pleased to announce that the Michigan Cancer Surveillance Program has been named as a Centers for Disease Control and Prevention (CDC) National Program of Cancer Registries (NPCR) Registry of Distinction for 2022. This distinction recognizes MCSP for providing high-quality data for cancer prevention and control activities at the local, regional, and national levels.
- #30 Michigan Cancer Surveillance Programhttps://www.michigan.gov/mdhhs/doing-business/providers/forms/michigan-cancer-surveillance-program
In 2022, the North American Association of Central Cancer Registries (NAACCR) awarded Gold Certification to the Michigan Cancer Surveillance Program for quality, completeness, and timeliness of 2019 cancer data. […] We are pleased to announce that the Michigan Cancer Surveillance Program has been named as a Centers for Disease Control and Prevention (CDC) National Program of Cancer Registries (NPCR) Registry of Distinction for 2022. This distinction recognizes MCSP for providing high-quality data for cancer prevention and control activities at the local, regional, and national levels.
- #31 How to use the Surveillance, Epidemiology, and End Results (SEER) data: research design and methodology | Military Medical Research | Full Texthttps://mmrjournal.biomedcentral.com/articles/10.1186/s40779-023-00488-2
In the United States (US), the Surveillance, Epidemiology, and End Results (SEER) program is the only comprehensive source of population-based information that includes stage of cancer at the time of diagnosis and patient survival data. […] The SEER program collects demographic, clinical, and outcome data on all malignancies diagnosed in representative geographic regions and subpopulations in the US. […] One of the main targets of the SEER program is to record cancer incidences and mortality rates for the entire US population. […] The SEER database can also be used in observational studies and national and local public health programs that could promote health through the prevention and control of diseases. […] More than 17,000 articles published from 1973 to 2020 used the SEER database as the primary source of data, and more than 86,000 articles referenced SEER in their studies. […] The SEER program currently records information on around 400,000 cancer cases annually. The volume of SEER data has been growing fast. […] The effective use of the SEER database for cancer research depends on the appropriate application of study designs and statistical models.
- #32 How to use the Surveillance, Epidemiology, and End Results (SEER) data: research design and methodology | Military Medical Research | Full Texthttps://mmrjournal.biomedcentral.com/articles/10.1186/s40779-023-00488-2
In the United States (US), the Surveillance, Epidemiology, and End Results (SEER) program is the only comprehensive source of population-based information that includes stage of cancer at the time of diagnosis and patient survival data. […] The SEER program collects demographic, clinical, and outcome data on all malignancies diagnosed in representative geographic regions and subpopulations in the US. […] One of the main targets of the SEER program is to record cancer incidences and mortality rates for the entire US population. […] The SEER database can also be used in observational studies and national and local public health programs that could promote health through the prevention and control of diseases. […] More than 17,000 articles published from 1973 to 2020 used the SEER database as the primary source of data, and more than 86,000 articles referenced SEER in their studies. […] The SEER program currently records information on around 400,000 cancer cases annually. The volume of SEER data has been growing fast. […] The effective use of the SEER database for cancer research depends on the appropriate application of study designs and statistical models.
- #33 How to use the Surveillance, Epidemiology, and End Results (SEER) data: research design and methodology | Military Medical Research | Full Texthttps://mmrjournal.biomedcentral.com/articles/10.1186/s40779-023-00488-2
In the United States (US), the Surveillance, Epidemiology, and End Results (SEER) program is the only comprehensive source of population-based information that includes stage of cancer at the time of diagnosis and patient survival data. […] The SEER program collects demographic, clinical, and outcome data on all malignancies diagnosed in representative geographic regions and subpopulations in the US. […] One of the main targets of the SEER program is to record cancer incidences and mortality rates for the entire US population. […] The SEER database can also be used in observational studies and national and local public health programs that could promote health through the prevention and control of diseases. […] More than 17,000 articles published from 1973 to 2020 used the SEER database as the primary source of data, and more than 86,000 articles referenced SEER in their studies. […] The SEER program currently records information on around 400,000 cancer cases annually. The volume of SEER data has been growing fast. […] The effective use of the SEER database for cancer research depends on the appropriate application of study designs and statistical models.
- #34 How to use the Surveillance, Epidemiology, and End Results (SEER) data: research design and methodology | Military Medical Research | Full Texthttps://mmrjournal.biomedcentral.com/articles/10.1186/s40779-023-00488-2
In the United States (US), the Surveillance, Epidemiology, and End Results (SEER) program is the only comprehensive source of population-based information that includes stage of cancer at the time of diagnosis and patient survival data. […] The SEER program collects demographic, clinical, and outcome data on all malignancies diagnosed in representative geographic regions and subpopulations in the US. […] One of the main targets of the SEER program is to record cancer incidences and mortality rates for the entire US population. […] The SEER database can also be used in observational studies and national and local public health programs that could promote health through the prevention and control of diseases. […] More than 17,000 articles published from 1973 to 2020 used the SEER database as the primary source of data, and more than 86,000 articles referenced SEER in their studies. […] The SEER program currently records information on around 400,000 cancer cases annually. The volume of SEER data has been growing fast. […] The effective use of the SEER database for cancer research depends on the appropriate application of study designs and statistical models.
- #35 How to use the Surveillance, Epidemiology, and End Results (SEER) data: research design and methodology | Military Medical Research | Full Texthttps://mmrjournal.biomedcentral.com/articles/10.1186/s40779-023-00488-2
In the United States (US), the Surveillance, Epidemiology, and End Results (SEER) program is the only comprehensive source of population-based information that includes stage of cancer at the time of diagnosis and patient survival data. […] The SEER program collects demographic, clinical, and outcome data on all malignancies diagnosed in representative geographic regions and subpopulations in the US. […] One of the main targets of the SEER program is to record cancer incidences and mortality rates for the entire US population. […] The SEER database can also be used in observational studies and national and local public health programs that could promote health through the prevention and control of diseases. […] More than 17,000 articles published from 1973 to 2020 used the SEER database as the primary source of data, and more than 86,000 articles referenced SEER in their studies. […] The SEER program currently records information on around 400,000 cancer cases annually. The volume of SEER data has been growing fast. […] The effective use of the SEER database for cancer research depends on the appropriate application of study designs and statistical models.
- #36 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu/
CSU informs global, regional, and national priorities for cancer control action via dedicated programmes of work in six complementary areas. […] CSU provides the Secretariat for the International Association of Cancer Registries (IACR), the professional society dedicated to fostering the aims and activities of cancer registries worldwide. This direct link to registries remains vital to CSUs remit of expanding the availability of quality-assured cancer data. The joint IARCIACR Cancer Incidence in Five Continents series is a flagship publication that compiles comparable cancer incidence rates across diverse registry populations worldwide. […] The Global Initiative for Cancer Registry Development (GICR) aims to markedly increase the coverage, quality, and use of data from PBCRs in low- and middle-income countries. Coordinated by IARC, the GICR brings together major international and national agencies committed to working collaboratively to improve cancer surveillance worldwide.
- #37 How epidemiology can help cancer control efforts and influence policy decisions | UICChttps://www.uicc.org/news-and-updates/blog/how-epidemiology-can-help-cancer-control-efforts-and-influence-policy
The magnitude of cancer, for example, varies between countries in terms of types and rates, according to the latest estimates from the International Agency for Research on Cancer (IARC). These international variations in the burden of many cancer types indicate the existence of different carcinogen exposures, highlighting the need for context-specific epidemiological research on cancer aetiology and local policy for prevention and early detection. […] Furthermore, cancer epidemiological analysis has shown a downward trend in cancer rates among older populations; however, an alarming increase in cancer rates among younger adults (aged 50 years) is emerging. […] Identifying the proportion of cancer that can be prevented or the fraction of cancer-related deaths that might be averted due to early detection efforts can empower prevention and awareness campaigns.
- #38 Cancer Surveillance and Health Services Research (SHSR) | American Cancer Societyhttps://www.cancer.org/research/surveillance-and-health-equity-science/surveillance-research.html
Identify and track emerging trends and inequalities in cancer occurrence and outcomes. […] Contribute to the advancement of surveillance research through scientific publications, conference participation, and collaborations across institutions and disciplines. […] Each year, we produce the ACS flagship report, Cancer Facts Figures, along with its companion article, Cancer Statistics, published in the ACS scientific journal CA: A Cancer Journal for Clinicians. […] These widely cited reports present the most current rates and trends in cancer incidence, mortality, and survival, as well as the most up-to-date information on symptoms, prevention, early detection, and treatment. […] The Surveillance team analyzes and interprets data to produce the ACS Facts Figures. Find the latest information including the most current trends in cancer occurrence survival, as well as information on prevention, early detection, treatment. […] Our team’s epidemiologists regularly update multiple Cancer Facts Figures reports and an interactive statistics website. We also publish additional cancer surveillance research, and we provide statistical support internally and externally.
- #39 Cancer Surveillance and Health Services Research (SHSR) | American Cancer Societyhttps://www.cancer.org/research/surveillance-and-health-equity-science/surveillance-research.html
Identify and track emerging trends and inequalities in cancer occurrence and outcomes. […] Contribute to the advancement of surveillance research through scientific publications, conference participation, and collaborations across institutions and disciplines. […] Each year, we produce the ACS flagship report, Cancer Facts Figures, along with its companion article, Cancer Statistics, published in the ACS scientific journal CA: A Cancer Journal for Clinicians. […] These widely cited reports present the most current rates and trends in cancer incidence, mortality, and survival, as well as the most up-to-date information on symptoms, prevention, early detection, and treatment. […] The Surveillance team analyzes and interprets data to produce the ACS Facts Figures. Find the latest information including the most current trends in cancer occurrence survival, as well as information on prevention, early detection, treatment. […] Our team’s epidemiologists regularly update multiple Cancer Facts Figures reports and an interactive statistics website. We also publish additional cancer surveillance research, and we provide statistical support internally and externally.
- #40 Cancer Surveillance Programs and Registries in the United States | American Cancer Societyhttps://www.cancer.org/cancer/managing-cancer/making-treatment-decisions/clinical-trials/cancer-surveillance-programs-and-registries-in-the-united-states.html
Population-based registries in cities and states collect and pull together information from multiple reporting facilities within their geographic regions that can include: Hospitals, Doctors offices, Nursing homes, Pathology laboratories, Ambulatory care facilities or clinics, Radiation and chemotherapy treatment centers, Other cancer care facilities. […] These registries provide data that can show things like new cancer cases (incidence) and death rates (mortality) across regions of the country. […] Information from cancer registries helps guide cancer prevention and control programs that are focused on changing certain behaviors (like smoking) and reducing other environmental risks. […] The National Cancer Data Base (NCDB) is a joint program of hospital registries of the Commission on Cancer (COC) and the American Cancer Society.
- #41 How epidemiology can help cancer control efforts and influence policy decisions | UICChttps://www.uicc.org/news-and-updates/blog/how-epidemiology-can-help-cancer-control-efforts-and-influence-policy
The magnitude of cancer, for example, varies between countries in terms of types and rates, according to the latest estimates from the International Agency for Research on Cancer (IARC). These international variations in the burden of many cancer types indicate the existence of different carcinogen exposures, highlighting the need for context-specific epidemiological research on cancer aetiology and local policy for prevention and early detection. […] Furthermore, cancer epidemiological analysis has shown a downward trend in cancer rates among older populations; however, an alarming increase in cancer rates among younger adults (aged 50 years) is emerging. […] Identifying the proportion of cancer that can be prevented or the fraction of cancer-related deaths that might be averted due to early detection efforts can empower prevention and awareness campaigns.
- #42 How epidemiology can help cancer control efforts and influence policy decisions | UICChttps://www.uicc.org/news-and-updates/blog/how-epidemiology-can-help-cancer-control-efforts-and-influence-policy
The magnitude of cancer, for example, varies between countries in terms of types and rates, according to the latest estimates from the International Agency for Research on Cancer (IARC). These international variations in the burden of many cancer types indicate the existence of different carcinogen exposures, highlighting the need for context-specific epidemiological research on cancer aetiology and local policy for prevention and early detection. […] Furthermore, cancer epidemiological analysis has shown a downward trend in cancer rates among older populations; however, an alarming increase in cancer rates among younger adults (aged 50 years) is emerging. […] Identifying the proportion of cancer that can be prevented or the fraction of cancer-related deaths that might be averted due to early detection efforts can empower prevention and awareness campaigns.
- #43 How epidemiology can help cancer control efforts and influence policy decisions | UICChttps://www.uicc.org/news-and-updates/blog/how-epidemiology-can-help-cancer-control-efforts-and-influence-policy
For years, the European Code Against Cancer has simplified epidemiological studies findings on risk factors, so that individual actions can be taken to help prevent cancer. […] This campaign was built on the fact that 40% of cancer cases can be prevented and another 40% of cancer-related deaths can be prevented if cancer is detected earlier. […] Epidemiologists work alongside biostatisticians and clinicians in assessing new drugs and other oncology-related technologies in terms of both benefits and risks, helping patients and clinicians make informed decisions and policymakers assess the cost-effectiveness of these new products in cancer control.
- #44 How epidemiology can help cancer control efforts and influence policy decisions | UICChttps://www.uicc.org/news-and-updates/blog/how-epidemiology-can-help-cancer-control-efforts-and-influence-policy
For years, the European Code Against Cancer has simplified epidemiological studies findings on risk factors, so that individual actions can be taken to help prevent cancer. […] This campaign was built on the fact that 40% of cancer cases can be prevented and another 40% of cancer-related deaths can be prevented if cancer is detected earlier. […] Epidemiologists work alongside biostatisticians and clinicians in assessing new drugs and other oncology-related technologies in terms of both benefits and risks, helping patients and clinicians make informed decisions and policymakers assess the cost-effectiveness of these new products in cancer control.
- #45 Enabling 21st Century Applications for Cancer Surveillance through Enhanced Registries and Beyond A Workshop | National Academieshttps://www.nationalacademies.org/our-work/enabling-21st-century-applications-for-cancer-surveillance-through-enhanced-registries-and-beyond-a-workshop
On July 29 and 30, 2024, a planning committee of the National Academies of Sciences, Engineering, and Medicine will organize a public workshop that will examine challenges with the current US system of cancer surveillance, as well as potential opportunities to modernize cancer surveillance programs to facilitate improvements in cancer research and cancer care. […] Population-based cancer surveillance has a pivotal role in assessing the nation’s progress in cancer control and helps inform research and care interventions aimed at reducing the burden of cancer on patients and communities, including the ability to identify health disparities in cancer outcomes. However, challenges with the current approach to cancer surveillance in the United States include delays and gaps in data collection, as well as inadequate infrastructure and workforce to keep pace with the informatics and treatment-related advances in cancer.
- #46 Enabling 21st Century Applications for Cancer Surveillance through Enhanced Registries and Beyond A Workshop | National Academieshttps://www.nationalacademies.org/our-work/enabling-21st-century-applications-for-cancer-surveillance-through-enhanced-registries-and-beyond-a-workshop
On July 29 and 30, 2024, a planning committee of the National Academies of Sciences, Engineering, and Medicine will organize a public workshop that will examine challenges with the current US system of cancer surveillance, as well as potential opportunities to modernize cancer surveillance programs to facilitate improvements in cancer research and cancer care. […] Population-based cancer surveillance has a pivotal role in assessing the nation’s progress in cancer control and helps inform research and care interventions aimed at reducing the burden of cancer on patients and communities, including the ability to identify health disparities in cancer outcomes. However, challenges with the current approach to cancer surveillance in the United States include delays and gaps in data collection, as well as inadequate infrastructure and workforce to keep pace with the informatics and treatment-related advances in cancer.
- #47 Enabling 21st Century Applications for Cancer Surveillance through Enhanced Registries and Beyond A Workshop | National Academieshttps://www.nationalacademies.org/our-work/enabling-21st-century-applications-for-cancer-surveillance-through-enhanced-registries-and-beyond-a-workshop
The workshop will feature invited presentations and panel discussions on topics that may include: Importance of population-based surveillance to understand and address health disparities and identify opportunities to improve the quality of cancer care. […] The current landscape of US cancer surveillance efforts (e.g., National Program of Cancer Registries, Surveillance, Epidemiology and End Results Program, National Cancer Database of the Commission on Cancer, as well as other hospital and population-based cancer registries). […] Possible strategies and innovations to address challenges with existing cancer surveillance infrastructure, workforce, data collection methodologies, and data completeness. […] Possible consequences of advances in informatics, cancer treatment, and research that rapidly outpace cancer surveillance infrastructure and methodologies, including challenges with timely assessment of the quality of cancer care and the potential to exacerbate disparities in cancer care and patient outcomes.
- #48 Enabling 21st Century Applications for Cancer Surveillance through Enhanced Registries and Beyond A Workshop | National Academieshttps://www.nationalacademies.org/our-work/enabling-21st-century-applications-for-cancer-surveillance-through-enhanced-registries-and-beyond-a-workshop
Potential strategies for improving cancer surveillance efforts through interdisciplinary collaboration and lessons learned from other surveillance systems. […] Potential opportunities to modernize cancer surveillance through appropriate use of technologies such as electronic health record systems, artificial intelligence, cloud-based data collection, and data linkages.
- #49 Enabling 21st Century Applications for Cancer Surveillance through Enhanced Registries and Beyond A Workshop | National Academieshttps://www.nationalacademies.org/our-work/enabling-21st-century-applications-for-cancer-surveillance-through-enhanced-registries-and-beyond-a-workshop
Potential strategies for improving cancer surveillance efforts through interdisciplinary collaboration and lessons learned from other surveillance systems. […] Potential opportunities to modernize cancer surveillance through appropriate use of technologies such as electronic health record systems, artificial intelligence, cloud-based data collection, and data linkages.
- #50 Cancer Surveillance Programs and Registries in the United States | American Cancer Societyhttps://www.cancer.org/cancer/managing-cancer/making-treatment-decisions/clinical-trials/cancer-surveillance-programs-and-registries-in-the-united-states.html
The NCI contracts with non-profit organizations to collect data on new cancer diagnoses in the designated geographic locations. […] The National Program of Cancer Registries (NPCR) of the Center for Disease Control and Prevention (CDC) supports population-based registries in state health departments. […] State cancer registries are computerized and have many public health uses. […] Together, the NPCR and the National Cancer Institutes SEER Program collect data for the entire US population. […] Future directions for cancer registries include support of more electronic information sharing.
- #51 Cancer Surveillance Informatics | NPCR | CDChttps://www.cdc.gov/national-program-cancer-registries/data-modernization/informatics.html
Cancer surveillance informatics focuses on identifying and evaluating how to use emerging technology to incorporate automated processes and electronic data exchange. […] Cancer surveillance informatics projects evaluate data streams, such as insurance claims data that may meet cancer registries’ requirements, alleviating the need to create special data streams for cancer registries. […] The National Program of Cancer Registries provides funds and technical assistance to central cancer registries.
- #52 Cancer Surveillance Informatics | NPCR | CDChttps://www.cdc.gov/national-program-cancer-registries/data-modernization/informatics.html
Cancer surveillance informatics focuses on identifying and evaluating how to use emerging technology to incorporate automated processes and electronic data exchange. […] Cancer surveillance informatics projects evaluate data streams, such as insurance claims data that may meet cancer registries’ requirements, alleviating the need to create special data streams for cancer registries. […] The National Program of Cancer Registries provides funds and technical assistance to central cancer registries.
- #53 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu/
IARC convened an expert workshop of multidisciplinary scientists to identify research priorities for reducing social inequalities in cancer, leading to the production of IARC Scientific Publication No. 168. On this basis, several research projects on social inequalities and cancer have been developed within CSU, including the documentation of social inequalities in cancer between and within countries, with a primary focus on the gradient of the association, as well as temporal and geographical variations. The IARC Cancer Inequalities Team (CIN), led by CSU, seeks to measure, understand, and reduce social inequalities in cancer. […] Building on several collaborative descriptive economic studies within CSU, the aim is to better understand the economic burden of cancer to national economies and health systems as well as to individuals and households.
- #54 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu/
IARC convened an expert workshop of multidisciplinary scientists to identify research priorities for reducing social inequalities in cancer, leading to the production of IARC Scientific Publication No. 168. On this basis, several research projects on social inequalities and cancer have been developed within CSU, including the documentation of social inequalities in cancer between and within countries, with a primary focus on the gradient of the association, as well as temporal and geographical variations. The IARC Cancer Inequalities Team (CIN), led by CSU, seeks to measure, understand, and reduce social inequalities in cancer. […] Building on several collaborative descriptive economic studies within CSU, the aim is to better understand the economic burden of cancer to national economies and health systems as well as to individuals and households.
- #55 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu/
IARC convened an expert workshop of multidisciplinary scientists to identify research priorities for reducing social inequalities in cancer, leading to the production of IARC Scientific Publication No. 168. On this basis, several research projects on social inequalities and cancer have been developed within CSU, including the documentation of social inequalities in cancer between and within countries, with a primary focus on the gradient of the association, as well as temporal and geographical variations. The IARC Cancer Inequalities Team (CIN), led by CSU, seeks to measure, understand, and reduce social inequalities in cancer. […] Building on several collaborative descriptive economic studies within CSU, the aim is to better understand the economic burden of cancer to national economies and health systems as well as to individuals and households.
- #56 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu/
IARC convened an expert workshop of multidisciplinary scientists to identify research priorities for reducing social inequalities in cancer, leading to the production of IARC Scientific Publication No. 168. On this basis, several research projects on social inequalities and cancer have been developed within CSU, including the documentation of social inequalities in cancer between and within countries, with a primary focus on the gradient of the association, as well as temporal and geographical variations. The IARC Cancer Inequalities Team (CIN), led by CSU, seeks to measure, understand, and reduce social inequalities in cancer. […] Building on several collaborative descriptive economic studies within CSU, the aim is to better understand the economic burden of cancer to national economies and health systems as well as to individuals and households.
- #57 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu/
IARC convened an expert workshop of multidisciplinary scientists to identify research priorities for reducing social inequalities in cancer, leading to the production of IARC Scientific Publication No. 168. On this basis, several research projects on social inequalities and cancer have been developed within CSU, including the documentation of social inequalities in cancer between and within countries, with a primary focus on the gradient of the association, as well as temporal and geographical variations. The IARC Cancer Inequalities Team (CIN), led by CSU, seeks to measure, understand, and reduce social inequalities in cancer. […] Building on several collaborative descriptive economic studies within CSU, the aim is to better understand the economic burden of cancer to national economies and health systems as well as to individuals and households.
- #58 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu-research/
Dynamic models to predict the long-term future burden under scenarios of roll-out of screening and vaccination programmes. […] Descriptive epidemiology of social inequalities in cancer, including: developing a research and data framework to study socioeconomic inequalities in cancer; integrating indicators into the European Cancer Inequalities Registry; and assessing inequalities in cancer mortality by education, sex, age, and residence. […] Estimate the productivity losses due to cancer-related premature mortality and morbidity from cancer at the global, regional, and national levels. […] Estimate health expenditure costs from cancer across countries. […] Estimate informal health-care costs for cancer at the global, regional, and national levels. […] Perform priority-setting in cancer prevention and control. Collaborations with WHO and partners to assist national policy-makers to obtain the best value for money by identifying priority interventions in cancer planning and evaluating the impact, cost, and feasibility of a package of interventions according to country capacity. […] The GICR was established to coordinate activities that increase the quality, availability, and use of cancer data worldwide.
- #59 What Comes Next: Cancer Epidemiology and Population Health | Duke University School of Medicinehttps://medschool.duke.edu/news/what-comes-next-cancer-epidemiology-and-population-health
Tomi Akinyemiju, PhD, is a professor in the Department of Population Health Sciences. She believes epidemiologists have a professional and moral imperative to ensure that medical and policy solutions are equitably applied to all populations. […] We need a lot more emphasis on prevention and health equity. […] In terms of prevention, the future of epidemiology is more personalized approaches tailored to each individuals unique context. […] In terms of risk prediction, the future of epidemiology is leveraging big data and tools like AI and machine learning for complex analyses on millions of data points. […] Even when we have interventions that work perfectly, we have to make sure there is equitable access to that knowledge and insight. In the United States, health equity remains a problem.
- #60 What Comes Next: Cancer Epidemiology and Population Health | Duke University School of Medicinehttps://medschool.duke.edu/news/what-comes-next-cancer-epidemiology-and-population-health
The future of epidemiology must consider that health risks are not distributed equally. Certain communities are more exposed to health risks like environmental exposures to toxic waste or are more heavily impacted by climate change or infection, as we saw with COVID-19. […] As the major health care provider in Durham, Duke has an obligation to address the health concerns in our backyard.
- #61 High-Risk Cancer Surveillance Clinic | Overlake Medical Center & Clinicshttps://www.overlakehospital.org/services/cancer-care/High-Risk-Cancer-Surveillance-Clinic
At the Overlake High-Risk Cancer Surveillance Clinic, we are committed to providing specialized care for individuals at elevated risk of developing cancer. […] Our mission is to empower individuals with a high family or genetic predisposition to cancer by offering comprehensive risk assessment, genetic testing, counseling and proactive care plans. […] If you are at increased risk for cancer, taking advantage of additional screening options may detect cancer at an earlier stage or decrease your risk for ever developing cancer in the first place. […] Surveillance and prevention are vital for anyone at a higher risk for hereditary cancers including breast, ovarian, gastric, colorectal, pancreatic, melanoma, endometrial and prostate cancers. […] Early detection is critical in high-risk individuals.
- #62 High-Risk Cancer Surveillance Clinic | Overlake Medical Center & Clinicshttps://www.overlakehospital.org/services/cancer-care/High-Risk-Cancer-Surveillance-Clinic
At the Overlake High-Risk Cancer Surveillance Clinic, we are committed to providing specialized care for individuals at elevated risk of developing cancer. […] Our mission is to empower individuals with a high family or genetic predisposition to cancer by offering comprehensive risk assessment, genetic testing, counseling and proactive care plans. […] If you are at increased risk for cancer, taking advantage of additional screening options may detect cancer at an earlier stage or decrease your risk for ever developing cancer in the first place. […] Surveillance and prevention are vital for anyone at a higher risk for hereditary cancers including breast, ovarian, gastric, colorectal, pancreatic, melanoma, endometrial and prostate cancers. […] Early detection is critical in high-risk individuals.
- #63 High-Risk Cancer Surveillance Clinic | Overlake Medical Center & Clinicshttps://www.overlakehospital.org/services/cancer-care/High-Risk-Cancer-Surveillance-Clinic
At the Overlake High-Risk Cancer Surveillance Clinic, we are committed to providing specialized care for individuals at elevated risk of developing cancer. […] Our mission is to empower individuals with a high family or genetic predisposition to cancer by offering comprehensive risk assessment, genetic testing, counseling and proactive care plans. […] If you are at increased risk for cancer, taking advantage of additional screening options may detect cancer at an earlier stage or decrease your risk for ever developing cancer in the first place. […] Surveillance and prevention are vital for anyone at a higher risk for hereditary cancers including breast, ovarian, gastric, colorectal, pancreatic, melanoma, endometrial and prostate cancers. […] Early detection is critical in high-risk individuals.
- #64 High-Risk Cancer Surveillance Clinic | Overlake Medical Center & Clinicshttps://www.overlakehospital.org/services/cancer-care/High-Risk-Cancer-Surveillance-Clinic
At the Overlake High-Risk Cancer Surveillance Clinic, we are committed to providing specialized care for individuals at elevated risk of developing cancer. […] Our mission is to empower individuals with a high family or genetic predisposition to cancer by offering comprehensive risk assessment, genetic testing, counseling and proactive care plans. […] If you are at increased risk for cancer, taking advantage of additional screening options may detect cancer at an earlier stage or decrease your risk for ever developing cancer in the first place. […] Surveillance and prevention are vital for anyone at a higher risk for hereditary cancers including breast, ovarian, gastric, colorectal, pancreatic, melanoma, endometrial and prostate cancers. […] Early detection is critical in high-risk individuals.
- #65 High-Risk Cancer Surveillance Clinic | Overlake Medical Center & Clinicshttps://www.overlakehospital.org/services/cancer-care/High-Risk-Cancer-Surveillance-Clinic
At the Overlake High-Risk Cancer Surveillance Clinic, we are committed to providing specialized care for individuals at elevated risk of developing cancer. […] Our mission is to empower individuals with a high family or genetic predisposition to cancer by offering comprehensive risk assessment, genetic testing, counseling and proactive care plans. […] If you are at increased risk for cancer, taking advantage of additional screening options may detect cancer at an earlier stage or decrease your risk for ever developing cancer in the first place. […] Surveillance and prevention are vital for anyone at a higher risk for hereditary cancers including breast, ovarian, gastric, colorectal, pancreatic, melanoma, endometrial and prostate cancers. […] Early detection is critical in high-risk individuals.
- #66 Active Surveillance for Cancer â Regional Cancer Care Associateshttps://www.regionalcancercare.org/services/active-surveillance/
Active surveillance may be recommended as part of a patients treatment plan. […] Active surveillance is part of a cancer treatment plan and qualifies as a form of expectant management: the process of monitoring early signs and symptoms of certain diseases. […] At Regional Cancer Care Associates, our active surveillance plan comprises state-of-the-art technology and an expert team of oncologists and specialists. […] Compared to other cancer treatments, active surveillance can be extremely beneficial. […] Active surveillance allows many patients to live a normal life while specialists keep a keen eye on their cancers progress. […] Active surveillance has proven to be exceptionally advantageous for men with low-risk prostate cancer. […] Active surveillance allows us to monitor cancer from the start, were able to constantly analyze the diseases effects and progress to determine our next steps before symptoms get worse.
- #67 Active Surveillance for Prostate Cancer | Memorial Sloan Kettering Cancer Centerhttps://www.mskcc.org/cancer-care/types/prostate/treatment/active-surveillance
Not all prostate cancers are the same. Some grow quickly and need treatment right away. Others grow slowly and are less likely to metastasize (spread) to other parts of your body. This kind of prostate cancer is low risk. […] If you have a prostate cancer that grows slowly, your healthcare provider may recommend active surveillance. […] Active surveillance is a form of treatment for prostate cancer. Its not the same as having no treatment. […] This treatment option helps people with slow-growing prostate cancer avoid possible side effects of surgery and radiation therapy, including: […] As part of active surveillance, you will have tests every few months to watch for any changes in your prostate. […] Your care team may notice changes in your prostate or tumor at any time during surveillance. If so, they may recommend you stop active surveillance. You may start another type of treatment, such as surgery or radiation therapy.
- #68 Active Surveillance for Prostate Cancer | Memorial Sloan Kettering Cancer Centerhttps://www.mskcc.org/cancer-care/types/prostate/treatment/active-surveillance
Not all prostate cancers are the same. Some grow quickly and need treatment right away. Others grow slowly and are less likely to metastasize (spread) to other parts of your body. This kind of prostate cancer is low risk. […] If you have a prostate cancer that grows slowly, your healthcare provider may recommend active surveillance. […] Active surveillance is a form of treatment for prostate cancer. Its not the same as having no treatment. […] This treatment option helps people with slow-growing prostate cancer avoid possible side effects of surgery and radiation therapy, including: […] As part of active surveillance, you will have tests every few months to watch for any changes in your prostate. […] Your care team may notice changes in your prostate or tumor at any time during surveillance. If so, they may recommend you stop active surveillance. You may start another type of treatment, such as surgery or radiation therapy.
- #69 Active Surveillance for Prostate Cancer | Memorial Sloan Kettering Cancer Centerhttps://www.mskcc.org/cancer-care/types/prostate/treatment/active-surveillance
Active surveillance can be the right choice for people with low-risk prostate cancers. Its a treatment option that matches how harmful the cancer is. […] During active surveillance, youll have tests every few months to look for any changes in your prostate. […] Your care team will use the results from these tests to monitor the cancer. […] Research shows that active surveillance is a safe treatment for people with low-risk cancers. […] Your care team monitors the cancer closely. They look for important changes to your prostate. If the cancer grows or spreads, your care team will know in time to take action. […] Yes. We cannot predict who will have prostate cancer that gets worse or needs treatment in the future. But we know its unlikely we will miss a change in the cancer if you follow your active surveillance schedule.
- #70 Active Surveillance for Cancer â Regional Cancer Care Associateshttps://www.regionalcancercare.org/services/active-surveillance/
Active surveillance may be recommended as part of a patients treatment plan. […] Active surveillance is part of a cancer treatment plan and qualifies as a form of expectant management: the process of monitoring early signs and symptoms of certain diseases. […] At Regional Cancer Care Associates, our active surveillance plan comprises state-of-the-art technology and an expert team of oncologists and specialists. […] Compared to other cancer treatments, active surveillance can be extremely beneficial. […] Active surveillance allows many patients to live a normal life while specialists keep a keen eye on their cancers progress. […] Active surveillance has proven to be exceptionally advantageous for men with low-risk prostate cancer. […] Active surveillance allows us to monitor cancer from the start, were able to constantly analyze the diseases effects and progress to determine our next steps before symptoms get worse.
- #71 Active Surveillance for Cancer â Regional Cancer Care Associateshttps://www.regionalcancercare.org/services/active-surveillance/
Active surveillance may be recommended as part of a patients treatment plan. […] Active surveillance is part of a cancer treatment plan and qualifies as a form of expectant management: the process of monitoring early signs and symptoms of certain diseases. […] At Regional Cancer Care Associates, our active surveillance plan comprises state-of-the-art technology and an expert team of oncologists and specialists. […] Compared to other cancer treatments, active surveillance can be extremely beneficial. […] Active surveillance allows many patients to live a normal life while specialists keep a keen eye on their cancers progress. […] Active surveillance has proven to be exceptionally advantageous for men with low-risk prostate cancer. […] Active surveillance allows us to monitor cancer from the start, were able to constantly analyze the diseases effects and progress to determine our next steps before symptoms get worse.
- #72 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu-research/
CSU is involved in many collaborative studies seeking to describe and interpret the changing magnitude and the transitional nature of cancer profiles around the world, through observation of variations by geography and over time. […] Enhancing understanding of global, regional, national, and subnational changes in cancer risk and survival and their determinants, including in relation to ongoing socioeconomic transitions and social inequalities. […] Generating scientific evidence related to the effectiveness of implementing primary prevention interventions, including the prevention or reduction of exposure to established modifiable risk factors. […] Enhancing understanding of the economic impact of cancer, to ensure equitable and sustainable health systems that are capable of effectively reducing the burden of cancer.
- #73 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu-research/
CSU is involved in many collaborative studies seeking to describe and interpret the changing magnitude and the transitional nature of cancer profiles around the world, through observation of variations by geography and over time. […] Enhancing understanding of global, regional, national, and subnational changes in cancer risk and survival and their determinants, including in relation to ongoing socioeconomic transitions and social inequalities. […] Generating scientific evidence related to the effectiveness of implementing primary prevention interventions, including the prevention or reduction of exposure to established modifiable risk factors. […] Enhancing understanding of the economic impact of cancer, to ensure equitable and sustainable health systems that are capable of effectively reducing the burden of cancer.
- #74 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu-research/
CSU is involved in many collaborative studies seeking to describe and interpret the changing magnitude and the transitional nature of cancer profiles around the world, through observation of variations by geography and over time. […] Enhancing understanding of global, regional, national, and subnational changes in cancer risk and survival and their determinants, including in relation to ongoing socioeconomic transitions and social inequalities. […] Generating scientific evidence related to the effectiveness of implementing primary prevention interventions, including the prevention or reduction of exposure to established modifiable risk factors. […] Enhancing understanding of the economic impact of cancer, to ensure equitable and sustainable health systems that are capable of effectively reducing the burden of cancer.
- #75 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu-research/
CSU is involved in many collaborative studies seeking to describe and interpret the changing magnitude and the transitional nature of cancer profiles around the world, through observation of variations by geography and over time. […] Enhancing understanding of global, regional, national, and subnational changes in cancer risk and survival and their determinants, including in relation to ongoing socioeconomic transitions and social inequalities. […] Generating scientific evidence related to the effectiveness of implementing primary prevention interventions, including the prevention or reduction of exposure to established modifiable risk factors. […] Enhancing understanding of the economic impact of cancer, to ensure equitable and sustainable health systems that are capable of effectively reducing the burden of cancer.
- #76 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu-research/
CSU is involved in many collaborative studies seeking to describe and interpret the changing magnitude and the transitional nature of cancer profiles around the world, through observation of variations by geography and over time. […] Enhancing understanding of global, regional, national, and subnational changes in cancer risk and survival and their determinants, including in relation to ongoing socioeconomic transitions and social inequalities. […] Generating scientific evidence related to the effectiveness of implementing primary prevention interventions, including the prevention or reduction of exposure to established modifiable risk factors. […] Enhancing understanding of the economic impact of cancer, to ensure equitable and sustainable health systems that are capable of effectively reducing the burden of cancer.
- #77 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu-research/
Conduct in-depth monitoring of key indicators of cancer incidence, survival, and mortality during and after future crises linked to pandemics or other major events. […] Explore reasons for disruptions to cancer services and effective mitigation strategies. […] Provide a tool to model the short-, medium-, and long-term impact of disruptions on cancer outcomes, to improve resilience in cancer control. […] Studies quantifying the proportion of cancer cases attributable to risk factors (updates or new factors: body mass index, smoking including smokeless tobacco use, physical inactivity, infectious agents, and ultraviolet radiation). […] Estimation of the burden of cancer using disability-adjusted life years (DALYs). […] Meeting global noncommunicable disease (NCD) targets. Using mortality trends to predict future premature deaths from cancer and other NCDs, as well as the contribution of risk factors and prevention strategies in achieving United Nations Sustainable Development Goals targets.
- #78 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu-research/
Conduct in-depth monitoring of key indicators of cancer incidence, survival, and mortality during and after future crises linked to pandemics or other major events. […] Explore reasons for disruptions to cancer services and effective mitigation strategies. […] Provide a tool to model the short-, medium-, and long-term impact of disruptions on cancer outcomes, to improve resilience in cancer control. […] Studies quantifying the proportion of cancer cases attributable to risk factors (updates or new factors: body mass index, smoking including smokeless tobacco use, physical inactivity, infectious agents, and ultraviolet radiation). […] Estimation of the burden of cancer using disability-adjusted life years (DALYs). […] Meeting global noncommunicable disease (NCD) targets. Using mortality trends to predict future premature deaths from cancer and other NCDs, as well as the contribution of risk factors and prevention strategies in achieving United Nations Sustainable Development Goals targets.
- #79 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu-research/
Conduct in-depth monitoring of key indicators of cancer incidence, survival, and mortality during and after future crises linked to pandemics or other major events. […] Explore reasons for disruptions to cancer services and effective mitigation strategies. […] Provide a tool to model the short-, medium-, and long-term impact of disruptions on cancer outcomes, to improve resilience in cancer control. […] Studies quantifying the proportion of cancer cases attributable to risk factors (updates or new factors: body mass index, smoking including smokeless tobacco use, physical inactivity, infectious agents, and ultraviolet radiation). […] Estimation of the burden of cancer using disability-adjusted life years (DALYs). […] Meeting global noncommunicable disease (NCD) targets. Using mortality trends to predict future premature deaths from cancer and other NCDs, as well as the contribution of risk factors and prevention strategies in achieving United Nations Sustainable Development Goals targets.
- #80 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu-research/
Conduct in-depth monitoring of key indicators of cancer incidence, survival, and mortality during and after future crises linked to pandemics or other major events. […] Explore reasons for disruptions to cancer services and effective mitigation strategies. […] Provide a tool to model the short-, medium-, and long-term impact of disruptions on cancer outcomes, to improve resilience in cancer control. […] Studies quantifying the proportion of cancer cases attributable to risk factors (updates or new factors: body mass index, smoking including smokeless tobacco use, physical inactivity, infectious agents, and ultraviolet radiation). […] Estimation of the burden of cancer using disability-adjusted life years (DALYs). […] Meeting global noncommunicable disease (NCD) targets. Using mortality trends to predict future premature deaths from cancer and other NCDs, as well as the contribution of risk factors and prevention strategies in achieving United Nations Sustainable Development Goals targets.
- #81 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu-research/
Conduct in-depth monitoring of key indicators of cancer incidence, survival, and mortality during and after future crises linked to pandemics or other major events. […] Explore reasons for disruptions to cancer services and effective mitigation strategies. […] Provide a tool to model the short-, medium-, and long-term impact of disruptions on cancer outcomes, to improve resilience in cancer control. […] Studies quantifying the proportion of cancer cases attributable to risk factors (updates or new factors: body mass index, smoking including smokeless tobacco use, physical inactivity, infectious agents, and ultraviolet radiation). […] Estimation of the burden of cancer using disability-adjusted life years (DALYs). […] Meeting global noncommunicable disease (NCD) targets. Using mortality trends to predict future premature deaths from cancer and other NCDs, as well as the contribution of risk factors and prevention strategies in achieving United Nations Sustainable Development Goals targets.
- #82 Cancer Surveillance Branch (CSU) – IARChttps://www.iarc.who.int/branches-csu-research/
Dynamic models to predict the long-term future burden under scenarios of roll-out of screening and vaccination programmes. […] Descriptive epidemiology of social inequalities in cancer, including: developing a research and data framework to study socioeconomic inequalities in cancer; integrating indicators into the European Cancer Inequalities Registry; and assessing inequalities in cancer mortality by education, sex, age, and residence. […] Estimate the productivity losses due to cancer-related premature mortality and morbidity from cancer at the global, regional, and national levels. […] Estimate health expenditure costs from cancer across countries. […] Estimate informal health-care costs for cancer at the global, regional, and national levels. […] Perform priority-setting in cancer prevention and control. Collaborations with WHO and partners to assist national policy-makers to obtain the best value for money by identifying priority interventions in cancer planning and evaluating the impact, cost, and feasibility of a package of interventions according to country capacity. […] The GICR was established to coordinate activities that increase the quality, availability, and use of cancer data worldwide.
- #83 What Comes Next: Cancer Epidemiology and Population Health | Duke University School of Medicinehttps://medschool.duke.edu/news/what-comes-next-cancer-epidemiology-and-population-health
Tomi Akinyemiju, PhD, is a professor in the Department of Population Health Sciences. She believes epidemiologists have a professional and moral imperative to ensure that medical and policy solutions are equitably applied to all populations. […] We need a lot more emphasis on prevention and health equity. […] In terms of prevention, the future of epidemiology is more personalized approaches tailored to each individuals unique context. […] In terms of risk prediction, the future of epidemiology is leveraging big data and tools like AI and machine learning for complex analyses on millions of data points. […] Even when we have interventions that work perfectly, we have to make sure there is equitable access to that knowledge and insight. In the United States, health equity remains a problem.
- #84 What Comes Next: Cancer Epidemiology and Population Health | Duke University School of Medicinehttps://medschool.duke.edu/news/what-comes-next-cancer-epidemiology-and-population-health
Tomi Akinyemiju, PhD, is a professor in the Department of Population Health Sciences. She believes epidemiologists have a professional and moral imperative to ensure that medical and policy solutions are equitably applied to all populations. […] We need a lot more emphasis on prevention and health equity. […] In terms of prevention, the future of epidemiology is more personalized approaches tailored to each individuals unique context. […] In terms of risk prediction, the future of epidemiology is leveraging big data and tools like AI and machine learning for complex analyses on millions of data points. […] Even when we have interventions that work perfectly, we have to make sure there is equitable access to that knowledge and insight. In the United States, health equity remains a problem.
- #85 What Comes Next: Cancer Epidemiology and Population Health | Duke University School of Medicinehttps://medschool.duke.edu/news/what-comes-next-cancer-epidemiology-and-population-health
Tomi Akinyemiju, PhD, is a professor in the Department of Population Health Sciences. She believes epidemiologists have a professional and moral imperative to ensure that medical and policy solutions are equitably applied to all populations. […] We need a lot more emphasis on prevention and health equity. […] In terms of prevention, the future of epidemiology is more personalized approaches tailored to each individuals unique context. […] In terms of risk prediction, the future of epidemiology is leveraging big data and tools like AI and machine learning for complex analyses on millions of data points. […] Even when we have interventions that work perfectly, we have to make sure there is equitable access to that knowledge and insight. In the United States, health equity remains a problem.
- #86 What Comes Next: Cancer Epidemiology and Population Health | Duke University School of Medicinehttps://medschool.duke.edu/news/what-comes-next-cancer-epidemiology-and-population-health
The future of epidemiology must consider that health risks are not distributed equally. Certain communities are more exposed to health risks like environmental exposures to toxic waste or are more heavily impacted by climate change or infection, as we saw with COVID-19. […] As the major health care provider in Durham, Duke has an obligation to address the health concerns in our backyard.
- #87 How epidemiology can help cancer control efforts and influence policy decisions | UICChttps://www.uicc.org/news-and-updates/blog/how-epidemiology-can-help-cancer-control-efforts-and-influence-policy
Epidemiology is the study of how diseases, such as cancer, spread and affect people. As a field, it can offer many opportunities to address challenges facing cancer control policies. […] Over the last 70 years, epidemiology has played a key role in describing the burden of cancer, identifying many of its risk factors, and assessing care outcomes. Evidence generated from epidemiological studies shows that around 40% of all cancer cases could be prevented, and further related deaths could be reduced through early detection and screening. […] One vital aspect of epidemiology is monitoring the magnitude and trends of cancer occurrence through population-based cancer registries, which enables the allocation of future prevention and early detection initiatives, as well as support facilities and manpower planning.
- #88 How epidemiology can help cancer control efforts and influence policy decisions | UICChttps://www.uicc.org/news-and-updates/blog/how-epidemiology-can-help-cancer-control-efforts-and-influence-policy
Epidemiology is the study of how diseases, such as cancer, spread and affect people. As a field, it can offer many opportunities to address challenges facing cancer control policies. […] Over the last 70 years, epidemiology has played a key role in describing the burden of cancer, identifying many of its risk factors, and assessing care outcomes. Evidence generated from epidemiological studies shows that around 40% of all cancer cases could be prevented, and further related deaths could be reduced through early detection and screening. […] One vital aspect of epidemiology is monitoring the magnitude and trends of cancer occurrence through population-based cancer registries, which enables the allocation of future prevention and early detection initiatives, as well as support facilities and manpower planning.
- #89 How epidemiology can help cancer control efforts and influence policy decisions | UICChttps://www.uicc.org/news-and-updates/blog/how-epidemiology-can-help-cancer-control-efforts-and-influence-policy
Epidemiology is the study of how diseases, such as cancer, spread and affect people. As a field, it can offer many opportunities to address challenges facing cancer control policies. […] Over the last 70 years, epidemiology has played a key role in describing the burden of cancer, identifying many of its risk factors, and assessing care outcomes. Evidence generated from epidemiological studies shows that around 40% of all cancer cases could be prevented, and further related deaths could be reduced through early detection and screening. […] One vital aspect of epidemiology is monitoring the magnitude and trends of cancer occurrence through population-based cancer registries, which enables the allocation of future prevention and early detection initiatives, as well as support facilities and manpower planning.
- #90 How epidemiology can help cancer control efforts and influence policy decisions | UICChttps://www.uicc.org/news-and-updates/blog/how-epidemiology-can-help-cancer-control-efforts-and-influence-policy
Epidemiology is the study of how diseases, such as cancer, spread and affect people. As a field, it can offer many opportunities to address challenges facing cancer control policies. […] Over the last 70 years, epidemiology has played a key role in describing the burden of cancer, identifying many of its risk factors, and assessing care outcomes. Evidence generated from epidemiological studies shows that around 40% of all cancer cases could be prevented, and further related deaths could be reduced through early detection and screening. […] One vital aspect of epidemiology is monitoring the magnitude and trends of cancer occurrence through population-based cancer registries, which enables the allocation of future prevention and early detection initiatives, as well as support facilities and manpower planning.
- #91 South Carolina Cancer Surveillance for Population Health Research and Outreach Tool | MUSC Hollings Cancer Centerhttps://hollingscancercenter.musc.edu/outreach/sc-spot-south-carolina-cancer-data-statistics
The South Carolina Cancer Surveillance for Population Health Research and Outreach Tool (SC SPOT) provides cancer-relevant data for all 46 counties in the state. Our goal is to share usable, understandable, and accessible data in order to foster research collaboration, empower communities, and improve health outcomes for all South Carolinians. […] Beyond visualization of cancer cases and deaths, we explore social determinants of health across South Carolina communities and illustrate the distribution of risk factors, health care access, and population sociodemographics. […] Join us on this journey of education, advocacy, and action as we work together towards improving cancer outcomes in South Carolina.