Łagodne guzy nadnerczy
Charakterystyka, pielęgnacja i opieka

Łagodne guzy nadnerczy, głównie gruczolaki, stanowią około 95% wszystkich guzów nadnerczy i występują u około 10% populacji. Mogą być nieczynne hormonalnie (incydentaloma) lub czynne, wydzielając nadmiar hormonów takich jak kortyzol, aldosteron, androgeny czy katecholaminy, co prowadzi do zespołów klinicznych: zespołu Cushinga, zespołu Conna, wirylizacji lub napadów nadciśnienia w przypadku pheochromocytoma. Diagnostyka opiera się na badaniach obrazowych (TK, MRI), ocenie hormonalnej (kortyzol, aldosteron, katecholaminy, DHEA) oraz testach dynamicznych, np. teście hamowania deksametazonem. Wskazaniem do adrenalektomii są guzy czynne hormonalnie, o średnicy >4 cm lub wykazujące szybki wzrost (>1 cm), z preferencją dla laparoskopowej adrenalektomii, która minimalizuje powikłania i skraca czas hospitalizacji. Po zabiegu konieczne jest monitorowanie hormonalne i kontrola parametrów metabolicznych, a w przypadku obustronnej adrenalektomii – dożywotnia suplementacja glikokortykoidów i mineralokortykoidów.

Wprowadzenie do łagodnych guzów nadnerczy

Łagodne guzy nadnerczy (inaczej łagodne nowotwory nadnerczy) są masami, które nie mają charakteru nowotworów złośliwych. Tworzą się w gruczołach nadnerczowych, które stanowią ważną część układu endokrynnego. Nadnercza produkują hormony przekazujące sygnały do niemal każdego narządu i tkanki w organizmie, kontrolując takie funkcje jak metabolizm, ciśnienie krwi oraz odpowiedź na stres.12

Większość łagodnych guzów nadnerczy nie powoduje objawów i nie wymaga leczenia. Jednak w niektórych przypadkach guzy te mogą produkować zwiększone ilości hormonów, co może prowadzić do różnych problemów zdrowotnych. Guzy nadnerczy są stosunkowo powszechne – łagodne guzy nadnerczy (znane również jako gruczolaki) występują u około 1 na 10 osób.34

Zdecydowana większość (ponad 95%) guzów nadnerczy ma charakter łagodny. Najczęstszym typem łagodnego guza nadnerczy jest gruczolak nadnercza (adenoma). Gruczolaki te mogą być hormonalnie czynne (wydzielające nadmierne ilości hormonów) lub nieczynne (niewydzielające hormonów).56

Klasyfikacja łagodnych guzów nadnerczy

Łagodne guzy nadnerczy można sklasyfikować na podstawie ich aktywności hormonalnej:78

  • Guzy niewydzielające (nieczynne hormonalnie) – nie produkują hormonów w nadmiernych ilościach i zwykle nie powodują objawów. Często są wykrywane przypadkowo podczas badań obrazowych wykonywanych z innych powodów, dlatego nazywane są również „incydentaloma nadnerczy”.
  • Guzy wydzielające (czynne hormonalnie) – produkują nadmierne ilości jednego lub więcej hormonów nadnerczy, co może prowadzić do objawów związanych z nadmiarem tych hormonów.

Typy guzów nadnerczy w zależności od wydzielanych hormonów

W zależności od rodzaju wydzielanych hormonów, czynne hormonalnie łagodne guzy nadnerczy mogą powodować różne zespoły kliniczne:910

  • Guzy wydzielające kortyzol – mogą prowadzić do zespołu Cushinga, charakteryzującego się otyłością centralną, nadciśnieniem, cukrzycą i osłabieniem mięśni
  • Guzy wydzielające aldosteron (aldosteronoma) – mogą powodować zespół Conna (pierwotny hiperaldosteronizm), charakteryzujący się nadciśnieniem tętniczym i niskim poziomem potasu
  • Guzy wydzielające androgeny – mogą prowadzić do hirsutyzmu i wirylizacji u kobiet
  • Pheochromocytoma – specyficzny typ guza rdzenia nadnerczy, który wydziela katecholaminy (adrenalinę i noradrenalinę), powodując napady nadciśnienia, pocenie się, bóle głowy i kołatanie serca

Objawy i rozpoznanie łagodnych guzów nadnerczy

Objawy łagodnych guzów nadnerczy zależą od tego, czy guz wydziela hormony, jaki hormon wydziela i w jakiej ilości. Wiele łagodnych guzów nadnerczy nie powoduje żadnych objawów, ponieważ nie wydzielają one hormonów.11

Guzy czynne hormonalnie mogą powodować objawy związane z nadmiarem odpowiednich hormonów, takie jak:1213

  • Nadciśnienie tętnicze
  • Zwiększenie masy ciała lub jej utrata
  • Cukrzyca lub zaburzenia gospodarki węglowodanowej
  • Zmiany skórne (np. rozstępy, siniaczenie)
  • Osłabienie mięśni
  • Zaburzenia gospodarki elektrolitowej (np. hipokaliemia)

Nawet guzy nieczynne hormonalnie mogą powodować objawy, jeśli są wystarczająco duże, aby uciskać sąsiednie narządy, co może prowadzić do bólu brzucha, boku lub pleców.14

Diagnostyka łagodnych guzów nadnerczy

Łagodne guzy nadnerczy często są wykrywane przypadkowo podczas badań obrazowych wykonywanych z innych powodów. Po ich wykryciu konieczna jest dalsza ocena w celu określenia prawdopodobieństwa złośliwości guza oraz jego aktywności hormonalnej.1516

Diagnostyka obejmuje:1718

  • Badania obrazowetomografia komputerowa (TK) lub rezonans magnetyczny (MRI) pomagają określić rozmiar guza, jego charakterystykę i prawdopodobieństwo złośliwości
  • Badania krwi i moczu – w celu oceny aktywności hormonalnej guza, mogą obejmować pomiar poziomów kortyzolu, aldosteronu, katecholamin i ich metabolitów oraz androgenów nadnerczowych, takich jak DHEA (dehydroepiandrosteron)
  • Testy dynamiczne – np. test hamowania deksametazonem do oceny wydzielania kortyzolu

Należy podkreślić, że ostateczne potwierdzenie, czy guz jest złośliwy czy łagodny, może nastąpić dopiero po jego usunięciu chirurgicznym i badaniu histopatologicznym.19

Opieka i leczenie łagodnych guzów nadnerczy

Podejście terapeutyczne do łagodnych guzów nadnerczy zależy od kilku czynników, w tym od aktywności hormonalnej guza, jego rozmiaru, prawdopodobieństwa złośliwości oraz obecności objawów klinicznych.2021

Obserwacja i monitorowanie

Dla małych, łagodnych guzów nadnerczy, które nie wydzielają hormonów (guzy nieczynne), często stosuje się strategię obserwacji. Obejmuje to:222324

  • Powtarzanie badań obrazowych 3-6 miesięcy po rozpoznaniu, a następnie co jeden lub dwa lata
  • Coroczną ocenę aktywności hormonalnej przez okres 5 lat
  • Regularne kontrole ciśnienia tętniczego i poziomu glukozy we krwi

Jeśli podczas obserwacji zostanie stwierdzone, że guz rośnie (wzrost o ponad 1 cm), staje się hormonalnie czynny lub osiąga rozmiar około 5 cm, zazwyczaj zaleca się leczenie chirurgiczne.2526

Leczenie farmakologiczne

Leczenie farmakologiczne może być stosowane w następujących sytuacjach:272829

  • Jako leczenie objawowe, gdy guz powoduje objawy związane z nadmiarem hormonów
  • Przed operacją, w celu kontroli objawów, np. nadciśnienia tętniczego
  • Jako główna metoda leczenia u pacjentów, którzy nie kwalifikują się do leczenia chirurgicznego z powodu zaawansowanego wieku, poważnych chorób współistniejących lub u tych, którzy odmawiają leczenia operacyjnego

Rodzaj stosowanych leków zależy od typu wydzielanego hormonu i może obejmować:3031

  • Leki blokujące syntezę kortyzolu (np. ketokonazol, metyrapon) w przypadku guzów wydzielających kortyzol
  • Antagonisty aldosteronu (np. spironolakton, eplerenon) w przypadku guzów wydzielających aldosteron
  • Leki blokujące receptory alfa- i beta-adrenergiczne w przypadku pheochromocytoma

Leczenie chirurgiczne

Adrenalektomia (usunięcie nadnercza) jest metodą z wyboru w leczeniu:323334

  • Wszystkich czynnych hormonalnie guzów nadnerczy, które wykazują biochemiczne cechy zespołu Cushinga lub pierwotnego hiperaldosteronizmu
  • Guzów nadnerczy o średnicy większej niż 4 cm, ze względu na zwiększone ryzyko złośliwości
  • Guzów, które wykazują szybki wzrost w badaniach obrazowych

Preferowaną metodą jest laparoskopowa adrenalektomia, która jest mniej inwazyjna niż tradycyjna operacja otwarta. Zabieg laparoskopowy oferuje liczne korzyści:353637

  • Mniejszy ból pooperacyjny
  • Krótszy pobyt w szpitalu (zwykle 1-2 dni)
  • Szybszy powrót do normalnej aktywności
  • Mniejsza utrata krwi podczas operacji
  • Mniejsze blizny pooperacyjne

W niektórych ośrodkach stosuje się również zaawansowane techniki, takie jak tylna adrenalektomia retroperitoneoskopowa (PRA) lub adrenalektomia wspomagana robotem, które mogą oferować dodatkowe korzyści dla odpowiednio wyselekcjonowanych pacjentów.3839

Opieka pooperacyjna i obserwacja długoterminowa

Po adrenalektomii pacjenci mogą wymagać specjalistycznej opieki pooperacyjnej, zwłaszcza jeśli usunięto oba nadnercza lub jeśli drugie nadnercze nie funkcjonuje prawidłowo.4041

Suplementacja hormonalna

Po jednostronnej adrenalektomii pozostałe nadnercze zwykle przejmuje funkcję usuniętego gruczołu. Jednak w przypadku obustronnej adrenalektomii lub gdy pozostałe nadnercze jest niewydolne, pacjenci będą wymagać dożywotniej suplementacji glikokortykoidów, a niekiedy również mineralokortykoidów.4243

Po jednostronnej adrenalektomii z powodu czynnego hormonalnie guza nadnercza może być konieczna tymczasowa suplementacja glikokortykoidów do czasu powrotu funkcji osi podwzgórze-przysadka-nadnercza, co może trwać kilka miesięcy.44

Monitorowanie po leczeniu

Po leczeniu łagodnego guza nadnerczy, pacjenci wymagają regularnego monitorowania, które obejmuje:4546

  • Regularne badania kontrolne, zwykle 6 miesięcy po operacji, a następnie co rok
  • Okresową ocenę poziomów hormonów
  • Monitorowanie ciśnienia tętniczego i gospodarki węglowodanowej
  • Badania obrazowe w celu wykrycia ewentualnych nawrotów lub guzów w drugim nadnerczu

W przypadku pacjentów z guzami wydzielającymi aldosteron, po usunięciu guza nadciśnienie tętnicze poprawia się u około 90% pacjentów, a u 30-60% pacjentów możliwe jest całkowite wyleczenie bez konieczności stosowania leków przeciwnadciśnieniowych. Sukces terapeutyczny zależy od wczesnego rozpoznania i leczenia, młodszego wieku pacjenta oraz krótkiego czasu trwania nadciśnienia.47

Wspieranie pacjentów z łagodnymi guzami nadnerczy

Opieka nad pacjentami z łagodnymi guzami nadnerczy wymaga podejścia wielodyscyplinarnego, angażującego specjalistów z różnych dziedzin medycyny.4849

Zespół wielodyscyplinarny

W skład zespołu zajmującego się pacjentami z guzami nadnerczy mogą wchodzić:505152

  • Endokrynolodzy – specjaliści w zakresie diagnostyki i leczenia hormonalnego
  • Chirurdzy endokrynologiczni – specjaliści w zakresie operacji gruczołów wydzielania wewnętrznego
  • Radiolodzy – specjaliści w zakresie badań obrazowych
  • Patolodzy – specjaliści w zakresie badań histopatologicznych
  • Pielęgniarki specjalistyczne i koordynatorzy opieki
  • Farmaceuci – specjaliści w zakresie farmakoterapii

Skuteczna współpraca między tymi specjalistami jest kluczowa dla zapewnienia optymalnej opieki nad pacjentami z guzami nadnerczy.53

Edukacja pacjentów

Ważnym elementem opieki nad pacjentami z łagodnymi guzami nadnerczy jest edukacja, obejmująca:5455

  • Informacje o naturze choroby i dostępnych opcjach leczenia
  • Instrukcje dotyczące przyjmowania leków, zwłaszcza steroidów (gdy są wskazane)
  • Naukę rozpoznawania objawów niewydolności nadnerczy, które wymagają natychmiastowej interwencji medycznej (zmęczenie, utrata masy ciała, bóle mięśni, osłabienie, ból brzucha, hipotonia ortostatyczna)
  • Znaczenie regularnych kontroli i badań

Wsparcie fizyczne i psychologiczne

Pacjenci z łagodnymi guzami nadnerczy mogą wymagać również:56

  • Rehabilitacji fizycznej po operacji
  • Terapii zajęciowej
  • Wsparcia psychologicznego
  • Uczestnictwa w grupach wsparcia dla pacjentów i ich rodzin

Te formy wsparcia mogą pomóc pacjentom w powrocie do normalnego funkcjonowania po leczeniu oraz w radzeniu sobie z psychologicznymi konsekwencjami choroby.57

Nowsze odkrycia i wyzwania w opiece nad pacjentami z łagodnymi guzami nadnerczy

Najnowsze badania dostarczają nowych informacji na temat wpływu łagodnych guzów nadnerczy na zdrowie kardiometaboliczne pacjentów.5859

Zespół subklinicznej autonomicznej sekrecji kortyzolu

Badania wskazują, że więcej guzów nadnerczy niż wcześniej sądzono wydziela nieprawidłowe poziomy kortyzolu, co może prowadzić do zespołu subklinicznej autonomicznej sekrecji kortyzolu (MACS – Mild Autonomous Cortisol Secretion). Według najnowszych badań, może to dotyczyć nawet połowy pacjentów z przypadkowo wykrytymi guzami nadnerczy, a nie jak wcześniej sądzono – jednej trzeciej.6061

MACS wiąże się ze zwiększonym ryzykiem zaburzeń kardiometabolicznych, takich jak:6263

  • Nadciśnienie tętnicze
  • Cukrzyca typu 2
  • Otyłość
  • Zaburzenia lipidowe

Co istotne, nawet pacjenci z nieczynymi hormonalnie guzami nadnerczy mogą mieć wyższą częstość występowania cukrzycy i nadciśnienia niż populacja ogólna, co może wskazywać na konsekwencje minimalnego, trudnego do wykrycia wydzielania kortyzolu.64

Zalecenia dotyczące monitorowania kardiometabolicznego

W świetle tych odkryć, eksperci zalecają, aby:6566

  • Wszyscy pacjenci z wykrytym łagodnym guzem nadnerczy byli badani w kierunku MACS
  • Regularnie mierzono u nich ciśnienie tętnicze i poziom glukozy we krwi
  • Dokładnie określano kardiometaboliczne konsekwencje nawet minimalnego wydzielania kortyzolu

Wczesne rozpoznanie tego stanu mogłoby pomóc wielu pacjentom, szczególnie kobietom po menopauzie, w otrzymaniu odpowiedniego leczenia lub we wprowadzeniu wcześniejszych modyfikacji stylu życia, aby zapobiec rozwojowi cukrzycy typu 2 lub zaawansowanej choroby sercowo-naczyniowej.67

Podsumowanie opieki nad pacjentami z łagodnymi guzami nadnerczy

Opieka nad pacjentami z łagodnymi guzami nadnerczy wymaga indywidualnego podejścia, uwzględniającego specyfikę każdego przypadku. Kluczowe elementy tej opieki obejmują:6869

  • Dokładną diagnostykę w celu określenia charakterystyki guza i jego aktywności hormonalnej
  • Indywidualne planowanie leczenia, uwzględniające zalety i wady każdej opcji terapeutycznej
  • W przypadku guzów wydzielających hormony – zwykle leczenie operacyjne, najczęściej laparoskopowe
  • W przypadku guzów niewydzielających hormonów – najczęściej strategię obserwacji z regularnym monitorowaniem
  • Odpowiednią opiekę pooperacyjną, w tym ewentualną suplementację hormonalną
  • Regularne monitorowanie w celu wczesnego wykrycia ewentualnych nawrotów lub powikłań
  • Wielodyscyplinarne podejście, angażujące różnych specjalistów
  • Edukację pacjenta i wsparcie psychologiczne

Dzięki postępom w diagnostyce i leczeniu, rokowanie dla pacjentów z łagodnymi guzami nadnerczy jest zazwyczaj bardzo dobre, pod warunkiem odpowiedniego i terminowego leczenia. Odsetek powikłań jest generalnie niski, a jakość życia pacjentów po leczeniu może być doskonała.7071

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  1. 09.04.2026
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Materiały źródłowe

  • #1 Benign adrenal tumors – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/benign-adrenal-tumors/symptoms-causes/syc-20356190
    Benign adrenal tumors are masses that aren’t cancer. They form in the adrenal glands. The adrenal glands are part of the endocrine system. These glands make hormones that send messages to nearly every organ and tissue in the body. […] Most benign adrenal tumors cause no symptoms and don’t need treatment. But sometimes these tumors make high levels of some hormones that can cause problems. […] Symptoms depend on whether the tumor makes hormones, what hormone it makes and how much it makes. But many benign adrenal gland tumors don’t cause symptoms because they don’t make hormones. […] The following might raise the risk of developing a benign adrenal tumor: A family history of benign adrenal tumors. […] Benign adrenal tumors care at Mayo Clinic.
  • #2 Benign adrenal tumors – Hancock Health
    https://www.hancockhealth.org/mayo-health-library/benign-adrenal-tumors/
    Benign adrenal tumors are masses that arent cancer. They form in the adrenal glands. The adrenal glands are part of the endocrine system. These glands make hormones that send messages to nearly every organ and tissue in the body. […] Most benign adrenal tumors cause no symptoms and dont need treatment. But sometimes these tumors make high levels of some hormones that can cause problems. […] Symptoms depend on whether the tumor makes hormones, what hormone it makes and how much it makes. But many benign adrenal gland tumors dont cause symptoms because they dont make hormones. […] Benign adrenal tumors often are found by chance on imaging thats done for another reason. A healthcare professional then looks at how likely the tumor is to be cancer and whether its making too much hormone. […] Along with a physical exam, a healthcare professional runs blood and urine tests to see if the tumor is making too much hormone. The tests also show which hormone the tumor is making.
  • #3 Benign adrenal tumors | UM Health-Sparrow
    https://www.uofmhealthsparrow.org/departments-conditions/conditions/benign-adrenal-tumors
    Benign adrenal tumors are masses that aren’t cancer. They form in the adrenal glands. The adrenal glands are part of the endocrine system. These glands make hormones that send messages to nearly every organ and tissue in the body. […] Most benign adrenal tumors cause no symptoms and don’t need treatment. But sometimes these tumors make high levels of some hormones that can cause problems. […] Symptoms depend on whether the tumor makes hormones, what hormone it makes and how much it makes. But many benign adrenal gland tumors don’t cause symptoms because they don’t make hormones. […] Benign adrenal tumors often don’t need treatment. Treatment depends on how likely the tumor is to become cancer. Treatment also might depend on whether the tumor is making hormones, the type of hormone it makes and how much it’s making.
  • #4 How Serious Is a Tumor on the Adrenal Gland? | UPMC HealthBeat
    https://share.upmc.com/2023/12/adrenal-gland-tumor/
    Adrenal tumor development in the adrenal glands is relatively common. These tumors can vary in terms of type, size, and symptom severity. […] An adrenal tumor is a typically benign (noncancerous) growth that develops inside the adrenal gland. In rare cases, adrenal tumors can become malignant (cancerous). Either case can affect hormone production. […] Benign adrenal tumors occur in about 1 in every 10 people. Benign adrenal tumors can still cause problems. In some cases, they can cause symptoms including increased sweating, weight gain or loss, and changes in blood pressure. […] Benign adrenal tumors (also known as adenomas) don’t spread outside the gland. These tumors are typically less than 2 inches (about 5 centimeters) across. Most often, they only occur in one adrenal gland. […] The vast majority of adrenal tumors are benign and asymptomatic and require no treatment. Surgery is the safest and most effective treatment for benign adrenal gland tumors that have grown or cause extreme symptoms.
  • #5 Adrenal Tumors and Adrenal Masses, an Overview
    https://www.adrenal.com/adrenal-tumors/overview
    Adrenal tumors are common. […] The good news is that over 95% of adrenal tumors are benign. […] Adrenal tumors that produce hormones always need to be removed because the excess hormones can cause toxic effects to your body, make you feel miserable and cause early death. […] Any functioning adrenal tumor should be removed by surgery (adrenalectomy). […] It is important to understand that most functional adrenal tumors are benign (non-cancerous). […] Yes, anytime you have a functional tumor, it needs to be removed. […] You need an adrenalectomy. […] We operate on more people with adrenal tumors than anybody else in the world and we are happy to see you and take care of you if you have an adrenal tumor.
  • #6 Benign Lesions of the Adrenal Gland | Patient Care
    https://weillcornell.org/services/urology/kidney-health/conditions-we-treat/benign-lesions-of-the-adrenal-gland
    Most adrenal lesions represent benign nonfunctioning masses called adenomas. […] Most adrenal tumors do not produce hormones (non-functional) and are found incidentally on CT or MR imaging, therefore not causing symptoms. […] Management of an incidentally found adrenal mass in a patient without a known primary malignancy will depend upon the size of the mass, its characteristics on the CT or MRI scan, and whether hormonal tests indicate that the tumor is producing excessive adrenal hormones. […] Treatment of adrenal tumors that cause Cushing’s syndrome include laparoscopic surgery and possible medication to reduce the production of cortisol. […] Treatment of an aldosterone producing tumor involves monitoring and replacing serum potassium levels and laparoscopic adrenal removal or partial adrenalectomy. […] The preferred treatment for adrenal pheochromocytoma is surgical removal of the functional adrenal tumors. […] The treatment of metastatic lesions of the adrenal gland depend upon the primary malignancy.
  • #7 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Adrenal adenomas are benign neoplasms that originate from the adrenal cortex. They can be categorized as either nonsecreting or functional. Nonfunctional adenomas and those with mild hormonal secretion may not produce noticeable symptoms and can remain asymptomatic. However, adenomas that exhibit significant hormonal activity often present with characteristic symptoms of Cushing syndrome, primary hyperaldosteronism, or hyperandrogenism. […] Overall, the prognosis for patients with adrenal adenomas is excellent if the condition is promptly diagnosed and treated. The complication rate is generally low. This activity aims to review the evaluation and management of adrenal adenomas and emphasizes the roles of the healthcare team in caring for patients with this condition. […] Unilateral adrenalectomy is the preferred treatment for adenomas larger than 4 cm, which are suspected to be malignant, or any hormonally active adenomas that show biochemical evidence of Cushing syndrome or primary hyperaldosteronism.
  • #8 Adenoma of the Adrenal Gland: Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17769-adrenal-adenoma
    Adrenal adenomas are benign (noncancerous) tumors in your adrenal glands. Your adrenal glands are small, triangular glands located atop both of your kidneys. They secrete hormones that help your body respond to stress. Your adrenal glands also release hormones that regulate your blood sugar, blood pressure and immune system, among other essential functions. […] Adrenal adenomas dont usually cause symptoms or require treatment. Some may lead to the overproduction of one or more normal adrenal hormones. […] Functioning adrenal adenomas can cause your adrenal glands to secrete excess amounts of one or more types of hormone. As a result, you may experience symptoms of certain adrenal disorders, including: […] Your treatment depends on whether the tumor is nonfunctioning or functioning (secreting excess hormones). If a nonfunctioning tumor is small, your healthcare provider may recommend periodic CT scans to ensure it doesnt increase in size or become functional. If the tumor grows rapidly or gets bigger (usually nearing 5 centimeters), your healthcare provider may recommend surgery. Large tumors and rapid growth increase the likelihood of a tumor becoming cancerous.
  • #9 Benign Lesions of the Adrenal Gland | Patient Care
    https://weillcornell.org/services/urology/kidney-health/conditions-we-treat/benign-lesions-of-the-adrenal-gland
    Most adrenal lesions represent benign nonfunctioning masses called adenomas. […] Most adrenal tumors do not produce hormones (non-functional) and are found incidentally on CT or MR imaging, therefore not causing symptoms. […] Management of an incidentally found adrenal mass in a patient without a known primary malignancy will depend upon the size of the mass, its characteristics on the CT or MRI scan, and whether hormonal tests indicate that the tumor is producing excessive adrenal hormones. […] Treatment of adrenal tumors that cause Cushing’s syndrome include laparoscopic surgery and possible medication to reduce the production of cortisol. […] Treatment of an aldosterone producing tumor involves monitoring and replacing serum potassium levels and laparoscopic adrenal removal or partial adrenalectomy. […] The preferred treatment for adrenal pheochromocytoma is surgical removal of the functional adrenal tumors. […] The treatment of metastatic lesions of the adrenal gland depend upon the primary malignancy.
  • #10 Adrenal Tumors | Baptist Health Miami Cancer Institute
    https://baptisthealth.net/services/cancer-care/miami-cancer-institute/our-approach/adult-cancers/endocrine-tumors/adrenal-tumors
    Adrenal cancers are rare, but benign (noncancerous) adrenal tumors are quite common. Even benign adrenal tumors can cause symptoms and require treatment. […] Types of adrenal tumors include: […] Non-functional adenomas. These are benign nodules within the adrenal gland that do not produce hormones. […] Certain hereditary conditions can increase your risk of developing an adrenal gland tumor. Talk to your doctor about your risk. If you are at high risk, be sure to be examined by your doctor every year.
  • #11 Benign adrenal tumors – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/benign-adrenal-tumors/symptoms-causes/syc-20356190
    Benign adrenal tumors are masses that aren’t cancer. They form in the adrenal glands. The adrenal glands are part of the endocrine system. These glands make hormones that send messages to nearly every organ and tissue in the body. […] Most benign adrenal tumors cause no symptoms and don’t need treatment. But sometimes these tumors make high levels of some hormones that can cause problems. […] Symptoms depend on whether the tumor makes hormones, what hormone it makes and how much it makes. But many benign adrenal gland tumors don’t cause symptoms because they don’t make hormones. […] The following might raise the risk of developing a benign adrenal tumor: A family history of benign adrenal tumors. […] Benign adrenal tumors care at Mayo Clinic.
  • #12 Diagnosing Adrenal Tumors | NYU Langone Health
    https://nyulangone.org/conditions/adrenal-tumors/diagnosis
    Most adrenal tumors are benign, meaning noncancerous. It is important to determine whether the tumor is functional, which means it produces elevated levels of hormones, or nonfunctional, which means it doesn’t. […] Most functional tumors are benign, but even benign tumors often need to be removed because the elevated hormone levels can lead to hypertension, or high blood pressure; stroke; heart attack; weight gain; diabetes; and other health problems. […] Nonfunctional tumors can be either benign or malignant. Both types can grow large enough to compress nearby organs and may cause pain in the abdomen, side, or back. […] Doctors may use blood or urine tests to check for abnormal levels of hormones in the body, which may be produced by adrenal tumors. […] Doctors can also test levels of adrenal androgens such as dehydroepiandrosterone, also known as DHEA, to determine whether an androgen-producing adrenal tumor may be present. […] Doctors are able to confirm whether a tumor is cancerous or benign after it is removed with surgery and examined under a microscope by a pathologist.
  • #13 Adenoma of the Adrenal Gland: Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17769-adrenal-adenoma
    Adrenal adenomas are benign (noncancerous) tumors in your adrenal glands. Your adrenal glands are small, triangular glands located atop both of your kidneys. They secrete hormones that help your body respond to stress. Your adrenal glands also release hormones that regulate your blood sugar, blood pressure and immune system, among other essential functions. […] Adrenal adenomas dont usually cause symptoms or require treatment. Some may lead to the overproduction of one or more normal adrenal hormones. […] Functioning adrenal adenomas can cause your adrenal glands to secrete excess amounts of one or more types of hormone. As a result, you may experience symptoms of certain adrenal disorders, including: […] Your treatment depends on whether the tumor is nonfunctioning or functioning (secreting excess hormones). If a nonfunctioning tumor is small, your healthcare provider may recommend periodic CT scans to ensure it doesnt increase in size or become functional. If the tumor grows rapidly or gets bigger (usually nearing 5 centimeters), your healthcare provider may recommend surgery. Large tumors and rapid growth increase the likelihood of a tumor becoming cancerous.
  • #14 Diagnosing Adrenal Tumors | NYU Langone Health
    https://nyulangone.org/conditions/adrenal-tumors/diagnosis
    Most adrenal tumors are benign, meaning noncancerous. It is important to determine whether the tumor is functional, which means it produces elevated levels of hormones, or nonfunctional, which means it doesn’t. […] Most functional tumors are benign, but even benign tumors often need to be removed because the elevated hormone levels can lead to hypertension, or high blood pressure; stroke; heart attack; weight gain; diabetes; and other health problems. […] Nonfunctional tumors can be either benign or malignant. Both types can grow large enough to compress nearby organs and may cause pain in the abdomen, side, or back. […] Doctors may use blood or urine tests to check for abnormal levels of hormones in the body, which may be produced by adrenal tumors. […] Doctors can also test levels of adrenal androgens such as dehydroepiandrosterone, also known as DHEA, to determine whether an androgen-producing adrenal tumor may be present. […] Doctors are able to confirm whether a tumor is cancerous or benign after it is removed with surgery and examined under a microscope by a pathologist.
  • #15 Benign adrenal tumors – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/benign-adrenal-tumors/diagnosis-treatment/drc-20567035
    Benign adrenal tumors often are found by chance on imaging that’s done for another reason. A healthcare professional then looks at how likely the tumor is to be cancer and whether it’s making too much hormone. […] Our caring team of Mayo Clinic experts can help you with your benign adrenal tumors-related health concerns. […] Benign adrenal tumors often don’t need treatment. Treatment depends on how likely the tumor is to become cancer. Treatment also might depend on whether the tumor is making hormones, the type of hormone it makes and how much it’s making. […] Treatment for small benign adrenal tumors that aren’t making hormones might involve watching the tumor. There might be repeat imaging tests 3 to 6 months after diagnosis, and then every one or two years. Watching also might involve testing hormones every year for five years.
  • #16 Benign adrenal tumors – Hancock Health
    https://www.hancockhealth.org/mayo-health-library/benign-adrenal-tumors/
    Benign adrenal tumors are masses that arent cancer. They form in the adrenal glands. The adrenal glands are part of the endocrine system. These glands make hormones that send messages to nearly every organ and tissue in the body. […] Most benign adrenal tumors cause no symptoms and dont need treatment. But sometimes these tumors make high levels of some hormones that can cause problems. […] Symptoms depend on whether the tumor makes hormones, what hormone it makes and how much it makes. But many benign adrenal gland tumors dont cause symptoms because they dont make hormones. […] Benign adrenal tumors often are found by chance on imaging thats done for another reason. A healthcare professional then looks at how likely the tumor is to be cancer and whether its making too much hormone. […] Along with a physical exam, a healthcare professional runs blood and urine tests to see if the tumor is making too much hormone. The tests also show which hormone the tumor is making.
  • #17 Diagnosing Adrenal Tumors | NYU Langone Health
    https://nyulangone.org/conditions/adrenal-tumors/diagnosis
    Most adrenal tumors are benign, meaning noncancerous. It is important to determine whether the tumor is functional, which means it produces elevated levels of hormones, or nonfunctional, which means it doesn’t. […] Most functional tumors are benign, but even benign tumors often need to be removed because the elevated hormone levels can lead to hypertension, or high blood pressure; stroke; heart attack; weight gain; diabetes; and other health problems. […] Nonfunctional tumors can be either benign or malignant. Both types can grow large enough to compress nearby organs and may cause pain in the abdomen, side, or back. […] Doctors may use blood or urine tests to check for abnormal levels of hormones in the body, which may be produced by adrenal tumors. […] Doctors can also test levels of adrenal androgens such as dehydroepiandrosterone, also known as DHEA, to determine whether an androgen-producing adrenal tumor may be present. […] Doctors are able to confirm whether a tumor is cancerous or benign after it is removed with surgery and examined under a microscope by a pathologist.
  • #18 Benign Lesions of the Adrenal Gland | Patient Care
    https://weillcornell.org/services/urology/kidney-health/conditions-we-treat/benign-lesions-of-the-adrenal-gland
    Most adrenal lesions represent benign nonfunctioning masses called adenomas. […] Most adrenal tumors do not produce hormones (non-functional) and are found incidentally on CT or MR imaging, therefore not causing symptoms. […] Management of an incidentally found adrenal mass in a patient without a known primary malignancy will depend upon the size of the mass, its characteristics on the CT or MRI scan, and whether hormonal tests indicate that the tumor is producing excessive adrenal hormones. […] Treatment of adrenal tumors that cause Cushing’s syndrome include laparoscopic surgery and possible medication to reduce the production of cortisol. […] Treatment of an aldosterone producing tumor involves monitoring and replacing serum potassium levels and laparoscopic adrenal removal or partial adrenalectomy. […] The preferred treatment for adrenal pheochromocytoma is surgical removal of the functional adrenal tumors. […] The treatment of metastatic lesions of the adrenal gland depend upon the primary malignancy.
  • #19 Diagnosing Adrenal Tumors | NYU Langone Health
    https://nyulangone.org/conditions/adrenal-tumors/diagnosis
    Most adrenal tumors are benign, meaning noncancerous. It is important to determine whether the tumor is functional, which means it produces elevated levels of hormones, or nonfunctional, which means it doesn’t. […] Most functional tumors are benign, but even benign tumors often need to be removed because the elevated hormone levels can lead to hypertension, or high blood pressure; stroke; heart attack; weight gain; diabetes; and other health problems. […] Nonfunctional tumors can be either benign or malignant. Both types can grow large enough to compress nearby organs and may cause pain in the abdomen, side, or back. […] Doctors may use blood or urine tests to check for abnormal levels of hormones in the body, which may be produced by adrenal tumors. […] Doctors can also test levels of adrenal androgens such as dehydroepiandrosterone, also known as DHEA, to determine whether an androgen-producing adrenal tumor may be present. […] Doctors are able to confirm whether a tumor is cancerous or benign after it is removed with surgery and examined under a microscope by a pathologist.
  • #20 Benign adrenal tumors – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/benign-adrenal-tumors/diagnosis-treatment/drc-20567035
    Benign adrenal tumors often are found by chance on imaging that’s done for another reason. A healthcare professional then looks at how likely the tumor is to be cancer and whether it’s making too much hormone. […] Our caring team of Mayo Clinic experts can help you with your benign adrenal tumors-related health concerns. […] Benign adrenal tumors often don’t need treatment. Treatment depends on how likely the tumor is to become cancer. Treatment also might depend on whether the tumor is making hormones, the type of hormone it makes and how much it’s making. […] Treatment for small benign adrenal tumors that aren’t making hormones might involve watching the tumor. There might be repeat imaging tests 3 to 6 months after diagnosis, and then every one or two years. Watching also might involve testing hormones every year for five years.
  • #21 Benign adrenal tumors | UM Health-Sparrow
    https://www.uofmhealthsparrow.org/departments-conditions/conditions/benign-adrenal-tumors
    Benign adrenal tumors are masses that aren’t cancer. They form in the adrenal glands. The adrenal glands are part of the endocrine system. These glands make hormones that send messages to nearly every organ and tissue in the body. […] Most benign adrenal tumors cause no symptoms and don’t need treatment. But sometimes these tumors make high levels of some hormones that can cause problems. […] Symptoms depend on whether the tumor makes hormones, what hormone it makes and how much it makes. But many benign adrenal gland tumors don’t cause symptoms because they don’t make hormones. […] Benign adrenal tumors often don’t need treatment. Treatment depends on how likely the tumor is to become cancer. Treatment also might depend on whether the tumor is making hormones, the type of hormone it makes and how much it’s making.
  • #22 Benign adrenal tumors – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/benign-adrenal-tumors/diagnosis-treatment/drc-20567035
    Benign adrenal tumors often are found by chance on imaging that’s done for another reason. A healthcare professional then looks at how likely the tumor is to be cancer and whether it’s making too much hormone. […] Our caring team of Mayo Clinic experts can help you with your benign adrenal tumors-related health concerns. […] Benign adrenal tumors often don’t need treatment. Treatment depends on how likely the tumor is to become cancer. Treatment also might depend on whether the tumor is making hormones, the type of hormone it makes and how much it’s making. […] Treatment for small benign adrenal tumors that aren’t making hormones might involve watching the tumor. There might be repeat imaging tests 3 to 6 months after diagnosis, and then every one or two years. Watching also might involve testing hormones every year for five years.
  • #23 Benign adrenal tumors // Middlesex Health
    https://middlesexhealth.org/learning-center/diseases-and-conditions/benign-adrenal-tumors
    Benign adrenal tumors often don’t need treatment. […] Treatment depends on how likely the tumor is to become cancer. Treatment also might depend on whether the tumor is making hormones, the type of hormone it makes and how much it’s making. […] Treatment for small benign adrenal tumors that aren’t making hormones might involve watching the tumor. There might be repeat imaging tests 3 to 6 months after diagnosis, and then every one or two years. Watching also might involve testing hormones every year for five years. […] If the tumor is getting bigger or causing symptoms, the symptoms might be treated with medicines. Medicines also might be used to treat symptoms such as high blood pressure before surgery. […] Surgery to remove the adrenal gland, called adrenalectomy, might be used to treat a benign adrenal tumor. The surgery may be done laparoscopically if the tumor is small and not likely to be cancer.
  • #24 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Medical management of hormone-secreting adenomas is typically reserved for unsuitable candidates for surgery due to advanced age, serious comorbidities, or patients who decline surgical correction. In such cases, the primary goal is to alleviate the symptoms and block hormone receptors. […] Hormonally inactive adenomas are initially managed by conducting reimaging in 3 to 6 months, followed by annual imaging for 1 to 2 years. In addition, repeat hormonal assessments should be performed annually for 5 years. If the mass exhibits growth exceeding 1 cm or becomes hormonally active, adrenalectomy is recommended. […] The decision to proceed with surgical correction is made following extensive discussions between the patient and their healthcare provider, considering the potential complications of the disease and the risks associated with surgery.
  • #25 Adenoma of the Adrenal Gland: Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17769-adrenal-adenoma
    Adrenal adenomas are benign (noncancerous) tumors in your adrenal glands. Your adrenal glands are small, triangular glands located atop both of your kidneys. They secrete hormones that help your body respond to stress. Your adrenal glands also release hormones that regulate your blood sugar, blood pressure and immune system, among other essential functions. […] Adrenal adenomas dont usually cause symptoms or require treatment. Some may lead to the overproduction of one or more normal adrenal hormones. […] Functioning adrenal adenomas can cause your adrenal glands to secrete excess amounts of one or more types of hormone. As a result, you may experience symptoms of certain adrenal disorders, including: […] Your treatment depends on whether the tumor is nonfunctioning or functioning (secreting excess hormones). If a nonfunctioning tumor is small, your healthcare provider may recommend periodic CT scans to ensure it doesnt increase in size or become functional. If the tumor grows rapidly or gets bigger (usually nearing 5 centimeters), your healthcare provider may recommend surgery. Large tumors and rapid growth increase the likelihood of a tumor becoming cancerous.
  • #26 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Medical management of hormone-secreting adenomas is typically reserved for unsuitable candidates for surgery due to advanced age, serious comorbidities, or patients who decline surgical correction. In such cases, the primary goal is to alleviate the symptoms and block hormone receptors. […] Hormonally inactive adenomas are initially managed by conducting reimaging in 3 to 6 months, followed by annual imaging for 1 to 2 years. In addition, repeat hormonal assessments should be performed annually for 5 years. If the mass exhibits growth exceeding 1 cm or becomes hormonally active, adrenalectomy is recommended. […] The decision to proceed with surgical correction is made following extensive discussions between the patient and their healthcare provider, considering the potential complications of the disease and the risks associated with surgery.
  • #27 Benign adrenal tumors // Middlesex Health
    https://middlesexhealth.org/learning-center/diseases-and-conditions/benign-adrenal-tumors
    Benign adrenal tumors often don’t need treatment. […] Treatment depends on how likely the tumor is to become cancer. Treatment also might depend on whether the tumor is making hormones, the type of hormone it makes and how much it’s making. […] Treatment for small benign adrenal tumors that aren’t making hormones might involve watching the tumor. There might be repeat imaging tests 3 to 6 months after diagnosis, and then every one or two years. Watching also might involve testing hormones every year for five years. […] If the tumor is getting bigger or causing symptoms, the symptoms might be treated with medicines. Medicines also might be used to treat symptoms such as high blood pressure before surgery. […] Surgery to remove the adrenal gland, called adrenalectomy, might be used to treat a benign adrenal tumor. The surgery may be done laparoscopically if the tumor is small and not likely to be cancer.
  • #28 Adrenal Tumors and Adrenal Cancer | Symptoms & Diagnosis | MedStar Health
    https://www.medstarhealth.org/services/adrenal-tumors
    Most growths are benign, and symptoms are treatable. […] Functioning tumors in the adrenal glands are typically benign but capable of becoming cancerous in the future. […] The adrenal cortex is where tumors and cancers can develop; however, they are rare, and most are benign (non-cancerous). […] Most tumors of the adrenal cortex are benign adenomas. […] If you have an adrenal tumor, your treatment is based on the tumor’s size, location, and whether or not it is cancerous. […] For most patients, surgery to remove the adrenal gland is the best treatment option. […] Our surgeons are particularly skilled at a less-invasive surgical procedure that is an option for an increasing number of patients called a laparoscopic adrenalectomy. […] Depending on your adrenal tumor type, your doctors may recommend drugs that block or reduce the effects of hormones.
  • #29 Adrenal Tumors – UChicago Medicine
    https://www.uchicagomedicine.org/cancer/types-treatments/adrenal-tumors
    When a tumor is benign and non-functional, treatment may not be necessary. You and your endocrinologist may decide to wait and see if any symptoms develop. […] If a patient is too fragile for surgery, our expert endocrinologists prescribe various medications to manage symptoms caused by adrenal tumors.
  • #30 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Medical management of hormone-secreting adenomas is typically reserved for unsuitable candidates for surgery due to advanced age, serious comorbidities, or patients who decline surgical correction. In such cases, the primary goal is to alleviate the symptoms and block hormone receptors. […] Hormonally inactive adenomas are initially managed by conducting reimaging in 3 to 6 months, followed by annual imaging for 1 to 2 years. In addition, repeat hormonal assessments should be performed annually for 5 years. If the mass exhibits growth exceeding 1 cm or becomes hormonally active, adrenalectomy is recommended. […] The decision to proceed with surgical correction is made following extensive discussions between the patient and their healthcare provider, considering the potential complications of the disease and the risks associated with surgery.
  • #31 ADRENAL TUMORS TREATMENTS – Comprehensive Urology
    https://comprehensive-urology.com/general-urology/adrenal-tumors/
    Medication – In mild cases, medications can assist in rebalancing the hormone levels that the tumor has affected. […] Chemotherapy – Drugs are injected into the blood stream that help reduce and kill lesions. […] Surgery – One or both adrenal glands may be removed to prevent further issues and medications will help replace hormones that the body is no longer able to produce on its own. […] Our team of highly-rated doctors undergoes training to diagnose and treat both benign and cancerous adrenal tumors. For more information about signs and symptoms of adrenal tumors, do not hesitate to contact us for more information by calling us at (310)-278-8330 or book an appointment here. Learn more about adrenal tumors near me today.
  • #32 Benign adrenal tumors – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/benign-adrenal-tumors/diagnosis-treatment/drc-20567035
    If the tumor is getting bigger or causing symptoms, the symptoms might be treated with medicines. Medicines also might be used to treat symptoms such as high blood pressure before surgery. […] Surgery to remove the adrenal gland, called adrenalectomy, might be used to treat a benign adrenal tumor. The surgery may be done laparoscopically if the tumor is small and not likely to be cancer.
  • #33 Benign adrenal tumors // Middlesex Health
    https://middlesexhealth.org/learning-center/diseases-and-conditions/benign-adrenal-tumors
    Benign adrenal tumors often don’t need treatment. […] Treatment depends on how likely the tumor is to become cancer. Treatment also might depend on whether the tumor is making hormones, the type of hormone it makes and how much it’s making. […] Treatment for small benign adrenal tumors that aren’t making hormones might involve watching the tumor. There might be repeat imaging tests 3 to 6 months after diagnosis, and then every one or two years. Watching also might involve testing hormones every year for five years. […] If the tumor is getting bigger or causing symptoms, the symptoms might be treated with medicines. Medicines also might be used to treat symptoms such as high blood pressure before surgery. […] Surgery to remove the adrenal gland, called adrenalectomy, might be used to treat a benign adrenal tumor. The surgery may be done laparoscopically if the tumor is small and not likely to be cancer.
  • #34 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Adrenal adenomas are benign neoplasms that originate from the adrenal cortex. They can be categorized as either nonsecreting or functional. Nonfunctional adenomas and those with mild hormonal secretion may not produce noticeable symptoms and can remain asymptomatic. However, adenomas that exhibit significant hormonal activity often present with characteristic symptoms of Cushing syndrome, primary hyperaldosteronism, or hyperandrogenism. […] Overall, the prognosis for patients with adrenal adenomas is excellent if the condition is promptly diagnosed and treated. The complication rate is generally low. This activity aims to review the evaluation and management of adrenal adenomas and emphasizes the roles of the healthcare team in caring for patients with this condition. […] Unilateral adrenalectomy is the preferred treatment for adenomas larger than 4 cm, which are suspected to be malignant, or any hormonally active adenomas that show biochemical evidence of Cushing syndrome or primary hyperaldosteronism.
  • #35 Diagnosis | Stanford Health Care
    https://stanfordhealthcare.org/medical-conditions/cancer/adrenal-tumor/diagnosis.html
    The skilled specialists of Stanfords Endocrine Tumor Program are experts in identifying, diagnosing, and treating cancerous and noncancerous (benign) adrenal tumors. […] Surgery is often the first treatment for benign or malignant (cancerous) adrenal tumors. Some benign tumors produce harmful hormones and should be removed. Stanford has nationally recognized expertise in the latest surgical techniques for the most complex cases. […] Whenever possible, we remove adrenal tumors laparoscopically. This less-invasive surgery generally allows you to leave the hospital after one or two days. After this minimally invasive surgery, you usually have less pain and can get back to your usual activities sooner than with traditional methods. […] Our Endocrine Tumor Program partners closely with the Stanford Hypertension Center to care for people who have hypertension (high blood pressure) from adrenal tumors. […] We also offer extensive support services during and after treatment, so that you can have the best experience possible. These services include physical and occupational rehabilitation and support groups for you and your family.
  • #36 State-of-the-Art Surgery for Adrenal Tumors | UCSF Department of Surgery
    https://endocrinesurgery.ucsf.edu/state-art-surgery-adrenal-tumors
    Sanziana Roman, MD, professor of surgery at UCSF and a senior endocrine surgeon, helped pioneer PRA and was among the first surgeons in the U.S. to perform the procedure. Over the past 7 years, she has done nearly 300 PRA surgeries. Roman says most adrenal patients with benign neoplasms are potential candidates for the procedure, and derive numerous clinical benefits. […] Surgery to remove the adrenal gland(s) through small incisions in the back offers significant benefits. The surgery is less invasive because surgeons do not cut as far into the body. Moreover, because the adrenal glands are located above the kidneys, abdominal organs such as the spleen, liver, pancreas and colon need not be repositioned during surgery. The operation is shorter, there is less blood loss, and recovery time is shortened. There is also a reduction in post-operative pain and a shorter hospital stay. […] PRA is not generally used where there are primary malignant adrenal masses, but can be used successfully for removing metastases which have spread to the adrenal glands from other cancers (such as lung, ovary, breast, kidney, and melanoma, among other).
  • #37 Adrenal Tumors and Nodules | Mays Cancer Center
    https://cancer.uthscsa.edu/cancer-care/types-and-treatments/adrenal-tumors-nodules
    At Mays Cancer Center, home to UT Health San Antonio MD Anderson Cancer Center, you have access to a team of experts working together to personalize your care. […] We offer a level of care not widely available in South Texas, including sophisticated procedures to remove adrenal tumors. […] Adrenal tumors are abnormal growths, some of which are cancerous. Tumors sometimes cause the adrenal glands to produce high levels of hormones. Benign (not cancerous) or cancerous tumors can cause hormone production. […] Adrenal nodules are abnormal growths on the adrenal glands that are often not cancerous. Nodules typically do not produce hormones. […] If the tumor is not producing hormones or pressing against nearby organs, you might not need treatment. We may recommend watchful waiting, regular exams and testing. This care helps us spot changes that may signal the need to remove it surgically. […] If the tumor is producing hormones or large enough to affect nearby organs, you need surgery. We typically use minimally invasive techniques, such as robotic surgery. This technology enables surgeons to guide instruments through delicate areas with a high degree of precision.
  • #38 State-of-the-Art Surgery for Adrenal Tumors | UCSF Department of Surgery
    https://endocrinesurgery.ucsf.edu/state-art-surgery-adrenal-tumors
    Sanziana Roman, MD, professor of surgery at UCSF and a senior endocrine surgeon, helped pioneer PRA and was among the first surgeons in the U.S. to perform the procedure. Over the past 7 years, she has done nearly 300 PRA surgeries. Roman says most adrenal patients with benign neoplasms are potential candidates for the procedure, and derive numerous clinical benefits. […] Surgery to remove the adrenal gland(s) through small incisions in the back offers significant benefits. The surgery is less invasive because surgeons do not cut as far into the body. Moreover, because the adrenal glands are located above the kidneys, abdominal organs such as the spleen, liver, pancreas and colon need not be repositioned during surgery. The operation is shorter, there is less blood loss, and recovery time is shortened. There is also a reduction in post-operative pain and a shorter hospital stay. […] PRA is not generally used where there are primary malignant adrenal masses, but can be used successfully for removing metastases which have spread to the adrenal glands from other cancers (such as lung, ovary, breast, kidney, and melanoma, among other).
  • #39 Treatment for Adrenal Tumors | Fox Chase Cancer Center – Philadelphia PA
    https://www.foxchase.org/clinical-care/conditions/adrenal-tumors/treatment
    Although most adrenal tumors are benign and do not need treatment, not all of them are harmless. […] Therefore, appropriate evaluation and management of these tumors requires deep and nuanced expertise. […] For patients requiring the removal of the adrenal glands, minimally invasive laparoscopic and robotic surgery are viable options. […] Our surgical experts are also comfortable with adrenal tissue preservation strategies and open surgical techniques when necessary. […] If medical therapy is necessary following surgery, our genitourinary oncologists work along with endocrinologists to provide a team-based approach to care, actively seeking out clinical trials for each patient when possible.
  • #40 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Following adrenalectomy, patients will need exogenous glucocorticoid supplementation during the recovery of the HPA axis, which may take several months. […] Patients should inform their physicians if they develop symptoms such as fatigue, weight loss, myalgias, weakness, abdominal pain, postural hypotension, or new atypical depressive symptoms. […] The management of adrenal adenomas requires close coordination among professionals from various medical fields. Effective collaboration among the primary team, which comprises physicians, nurse practitioners, physician assistants, nurses, and pharmacists, is of paramount importance. […] Adrenal adenomas cannot be predicted or prevented. It is recommended that patients consult with endocrinology specialists for further evaluation whenever abnormal findings are detected during an imaging study, regardless of whether they are related to the initial issue that prompted the specific testing.
  • #41 Adrenal Tumors – Brigham and Women’s Hospital
    https://www.brighamandwomens.org/surgery/surgical-oncology/endocrine/adrenal-tumors
    Adrenal tumors can be either benign (non-cancerous) or malignant (cancerous) and require treatment from medical and surgical experts who specialize in these uncommon growths. […] Careful monitoring and the involvement of an experienced endocrine surgeon are important to the successful outcome for patients with adrenal disorders. […] The day of surgery, you will be taken cared for in the operating room by endocrine surgeons, anesthesiologists and nurses who specialize in surgery for patients with adrenal tumors. After surgery, you will recover in the post-surgical care unit where you will receive comprehensive care by an experienced surgical and nursing staff.
  • #42 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Following adrenalectomy, patients will need exogenous glucocorticoid supplementation during the recovery of the HPA axis, which may take several months. […] Patients should inform their physicians if they develop symptoms such as fatigue, weight loss, myalgias, weakness, abdominal pain, postural hypotension, or new atypical depressive symptoms. […] The management of adrenal adenomas requires close coordination among professionals from various medical fields. Effective collaboration among the primary team, which comprises physicians, nurse practitioners, physician assistants, nurses, and pharmacists, is of paramount importance. […] Adrenal adenomas cannot be predicted or prevented. It is recommended that patients consult with endocrinology specialists for further evaluation whenever abnormal findings are detected during an imaging study, regardless of whether they are related to the initial issue that prompted the specific testing.
  • #43 Adrenal Tumor – Barrow Neurological Institutephone iconphone iconGroup 9Group 49
    https://www.barrowneuro.org/condition/adrenal-tumor/
    For functional adrenal tumors, surgery is the primary treatment, but in cases where surgery is not viable, medications, radiation, or chemotherapy may be used. […] If one adrenal gland is removed, your other adrenal gland should continue to work normally. In the event both adrenal glands need to be removed, you will need to take medicine to replace the hormones your adrenal glands made. […] Doctors use nonsurgical treatments when surgery for an adrenal tumor isn’t an option due to high surgical risk, an inoperable tumor, or advanced cancer. The following therapies can also be used in conjunction with surgery. […] The prognosis for someone with an adrenal tumor is, overall, favorable. However, this depends on the type of adrenal tumor, its size, and whether or not it produces hormones. Most adrenal tumors are slow-growing, noncancerous growths and don’t require treatment. Adrenocortical carcinoma is more serious, so early detection is key because surgery can be curative if this tumor is caught in Stage 1 or Stage 2. If caught at a later stage, like Stage 3 or Stage 4, chemotherapy, targeted therapy, or radiation can help extend life but may not be curative. […] While there is no guaranteed way to prevent adrenal tumors, specific steps may help reduce the risk, especially if you have a genetic predisposition or an underlying health condition.
  • #44 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Following adrenalectomy, patients will need exogenous glucocorticoid supplementation during the recovery of the HPA axis, which may take several months. […] Patients should inform their physicians if they develop symptoms such as fatigue, weight loss, myalgias, weakness, abdominal pain, postural hypotension, or new atypical depressive symptoms. […] The management of adrenal adenomas requires close coordination among professionals from various medical fields. Effective collaboration among the primary team, which comprises physicians, nurse practitioners, physician assistants, nurses, and pharmacists, is of paramount importance. […] Adrenal adenomas cannot be predicted or prevented. It is recommended that patients consult with endocrinology specialists for further evaluation whenever abnormal findings are detected during an imaging study, regardless of whether they are related to the initial issue that prompted the specific testing.
  • #45 Adenoma of the Adrenal Gland: Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17769-adrenal-adenoma
    Treatments for functioning tumors almost always involve surgery. […] Follow your healthcare providers guidance about how often you should be tested if youve been diagnosed with a nonfunctioning adrenal adenoma. Depending on your tumor, your healthcare provider may recommend periodic CT scans or hormone testing. […] If your tumor turns out to be an adrenal adenoma, your healthcare provider can run tests to see if its causing an overproduction of hormones. If it is, surgery can help. If your tumor is nonfunctioning, your healthcare provider can monitor it to ensure it doesnt negatively impact your hormones. If theres a concern that it could become malignant, your healthcare provider can remove it.
  • #46 Benign Feminizing Adrenal Tumor in an Adult Male | Ochsner Journal
    https://www.ochsnerjournal.org/content/20/3/311
    Surgical resection generally results in reduced gynecomastia and the other feminizing features associated with feminizing adrenal tumors. […] Given the sentinel event after benign histopathology in the case reported by Anda Melero et al, primary care physician follow-up of these patients is imperative. Follow-up at 6 months postoperatively and yearly thereafter should include an adequate history for identifying reoccurring symptoms, a physical examination, and trending of hormonal levels. […] This report substantiates the importance of radiologic and histopathologic findings in the diagnosis of these tumors, as well as the need for regular postoperative follow-up with trending of hormonal levels.
  • #47 Adrenal Disease & Surgery | The Oregon Clinic
    https://www.oregonclinic.com/resource/adrenal-disease-surgery/
    Adenoma is the most common type of adrenal gland tumor. It is a noncancerous tumor that usually does not cause symptoms, and, if it is small, often does not need treatment. […] Once the appropriate diagnosis is made, recommendations regarding observation with follow up, treatment with medication or surgical intervention will be made. The majority of patients requiring removal of their adrenal tumor are candidates for minimally invasive surgery using laparoscopy. This procedure is performed under general anesthetic and 3-4 small incisions, each measuring to inch, are made for introduction of a camera and miniature instruments for removal of the abnormal gland. […] Laparoscopic adrenalectomy or, in appropriately selected patients, endoscopic posterior adrenalectomy, is associated with low morbidity and mortality and results in improved hypertension in about 90% of patients. Thirty to 60% of cases will result in cure without need for additional antihypertensives. Success is dependent on timely treatment at a younger age and early in the onset of hypertension.
  • #48 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Following adrenalectomy, patients will need exogenous glucocorticoid supplementation during the recovery of the HPA axis, which may take several months. […] Patients should inform their physicians if they develop symptoms such as fatigue, weight loss, myalgias, weakness, abdominal pain, postural hypotension, or new atypical depressive symptoms. […] The management of adrenal adenomas requires close coordination among professionals from various medical fields. Effective collaboration among the primary team, which comprises physicians, nurse practitioners, physician assistants, nurses, and pharmacists, is of paramount importance. […] Adrenal adenomas cannot be predicted or prevented. It is recommended that patients consult with endocrinology specialists for further evaluation whenever abnormal findings are detected during an imaging study, regardless of whether they are related to the initial issue that prompted the specific testing.
  • #49 Adrenal Tumors – UChicago Medicine
    https://www.uchicagomedicine.org/cancer/types-treatments/adrenal-tumors
    Your adrenal glands produce a number of important hormones, including cortisol and aldosterone. When a tumor develops on these glands, which are located above your kidneys, hormone production can be affected. […] Most tumors, or growths, on the adrenal glands are not cancerous. But all adrenal tumors need to be treated or watched carefully to ensure they dont cause serious problems. […] At the University of Chicago Medicine, our nationally respected endocrinologists and endocrine surgeons collaborate to identify the best way to treat benign adrenal tumors, using the most advanced medical and surgical approaches. […] Because our endocrinologists are also experts in managing high blood pressure, diabetes and other conditions caused by hormonal changes, we can help patients effectively manage symptoms caused by an adrenal tumor or by the removal of an adrenal gland.
  • #50 Adrenal Tumors – UChicago Medicine
    https://www.uchicagomedicine.org/cancer/types-treatments/adrenal-tumors
    Your adrenal glands produce a number of important hormones, including cortisol and aldosterone. When a tumor develops on these glands, which are located above your kidneys, hormone production can be affected. […] Most tumors, or growths, on the adrenal glands are not cancerous. But all adrenal tumors need to be treated or watched carefully to ensure they dont cause serious problems. […] At the University of Chicago Medicine, our nationally respected endocrinologists and endocrine surgeons collaborate to identify the best way to treat benign adrenal tumors, using the most advanced medical and surgical approaches. […] Because our endocrinologists are also experts in managing high blood pressure, diabetes and other conditions caused by hormonal changes, we can help patients effectively manage symptoms caused by an adrenal tumor or by the removal of an adrenal gland.
  • #51 What Is Adrenal Cancer? | Board Certified Radiation Oncologists located in Avondale, Chandler, Chandler, Gilbert, Mesa, Phoenix, Scottsdale, Surprise, Peoria, Fountain Hills, Apache Junction, Sun City, Goodyear, Glendale, Tempe, Wickenburg and Phoenix, A
    https://www.arizonaccc.com/post/what-is-adrenal-cancer
    Non-cancerous adrenal cortex adenomas appear as small tumors less than two inches in diameter. […] Adrenal adenomas cause no symptoms. Most people do not know they have a tumor until a doctor discovers them in unrelated abdominal CT or MRI scans. […] Many people need two or more types of treatment, in a combined approach. Your treatment team guides you through your procedures and therapies. Members of this treatment team include: Nurse practitioners, Nurses.
  • #52 What are Adrenal Tumors? Symptoms, Risk Factors & Treatments | MD Anderson Cancer Center
    https://www.mdanderson.org/cancer-types/adrenal-tumors.html
    Adrenal tumors can be malignant (cancer) or benign (not cancerous). Even benign adrenal tumors can be dangerous or cause uncomfortable symptoms. […] MD Anderson’s Endocrine Center has one of the nation’s few programs dedicated to providing personalized care for benign and malignant adrenal tumors, a group of complex and diverse disorders. […] Your adrenal tumor treatment includes the most advanced methods with the least impact on the body, including targeted therapies and nuclear medicine approaches. If surgery is necessary, our surgeons are often able to perform less-invasive procedures.
  • #53 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Following adrenalectomy, patients will need exogenous glucocorticoid supplementation during the recovery of the HPA axis, which may take several months. […] Patients should inform their physicians if they develop symptoms such as fatigue, weight loss, myalgias, weakness, abdominal pain, postural hypotension, or new atypical depressive symptoms. […] The management of adrenal adenomas requires close coordination among professionals from various medical fields. Effective collaboration among the primary team, which comprises physicians, nurse practitioners, physician assistants, nurses, and pharmacists, is of paramount importance. […] Adrenal adenomas cannot be predicted or prevented. It is recommended that patients consult with endocrinology specialists for further evaluation whenever abnormal findings are detected during an imaging study, regardless of whether they are related to the initial issue that prompted the specific testing.
  • #54 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Following adrenalectomy, patients will need exogenous glucocorticoid supplementation during the recovery of the HPA axis, which may take several months. […] Patients should inform their physicians if they develop symptoms such as fatigue, weight loss, myalgias, weakness, abdominal pain, postural hypotension, or new atypical depressive symptoms. […] The management of adrenal adenomas requires close coordination among professionals from various medical fields. Effective collaboration among the primary team, which comprises physicians, nurse practitioners, physician assistants, nurses, and pharmacists, is of paramount importance. […] Adrenal adenomas cannot be predicted or prevented. It is recommended that patients consult with endocrinology specialists for further evaluation whenever abnormal findings are detected during an imaging study, regardless of whether they are related to the initial issue that prompted the specific testing.
  • #55 Adrenal Cortex Tumors | VCA Animal Hospitals
    https://vcahospitals.com/know-your-pet/adrenal-cortex-tumors
    In dogs, benign tumors of the adrenal cortex are the most common type and are seen in older animals. […] Medical treatment of these tumors involves the use of toxic drugs so monitoring of your animal is essential. Good observation by you will enable this to be more accurate and improves the outlook because relapses are common. Please ensure you understand what you should check, how frequently and signs you should look out for. […] Adrenal cortical tumors that can be treated surgically may be cured, but it is more probable that on-going medical treatment will be necessary. The treatment requires regular monitoring and life expectancy is variable from days to ten years and averaging less than three years. Because relapses are common, good observation by you, the owner, improves the outlook by catching relapses in their early stage.
  • #56 Diagnosis | Stanford Health Care
    https://stanfordhealthcare.org/medical-conditions/cancer/adrenal-tumor/diagnosis.html
    The skilled specialists of Stanfords Endocrine Tumor Program are experts in identifying, diagnosing, and treating cancerous and noncancerous (benign) adrenal tumors. […] Surgery is often the first treatment for benign or malignant (cancerous) adrenal tumors. Some benign tumors produce harmful hormones and should be removed. Stanford has nationally recognized expertise in the latest surgical techniques for the most complex cases. […] Whenever possible, we remove adrenal tumors laparoscopically. This less-invasive surgery generally allows you to leave the hospital after one or two days. After this minimally invasive surgery, you usually have less pain and can get back to your usual activities sooner than with traditional methods. […] Our Endocrine Tumor Program partners closely with the Stanford Hypertension Center to care for people who have hypertension (high blood pressure) from adrenal tumors. […] We also offer extensive support services during and after treatment, so that you can have the best experience possible. These services include physical and occupational rehabilitation and support groups for you and your family.
  • #57 Diagnosis | Stanford Health Care
    https://stanfordhealthcare.org/medical-conditions/cancer/adrenal-tumor/diagnosis.html
    The skilled specialists of Stanfords Endocrine Tumor Program are experts in identifying, diagnosing, and treating cancerous and noncancerous (benign) adrenal tumors. […] Surgery is often the first treatment for benign or malignant (cancerous) adrenal tumors. Some benign tumors produce harmful hormones and should be removed. Stanford has nationally recognized expertise in the latest surgical techniques for the most complex cases. […] Whenever possible, we remove adrenal tumors laparoscopically. This less-invasive surgery generally allows you to leave the hospital after one or two days. After this minimally invasive surgery, you usually have less pain and can get back to your usual activities sooner than with traditional methods. […] Our Endocrine Tumor Program partners closely with the Stanford Hypertension Center to care for people who have hypertension (high blood pressure) from adrenal tumors. […] We also offer extensive support services during and after treatment, so that you can have the best experience possible. These services include physical and occupational rehabilitation and support groups for you and your family.
  • #58 Risk for Type 2 Diabetes, Hypertension from Benign Adrenal Tumors Higher Than Thought | Inside Precision Medicine
    https://www.insideprecisionmedicine.com/news-and-features/risk-for-type-2-diabetes-hypertension-from-benign-adrenal-tumors-higher-than-thought/
    People with benign adrenal tumors are at higher risk for type 2 diabetes and high blood pressure than previously understood, according to new research from the University of Birmingham in the U.K. […] The study, published in the Annals of Internal Medicine, revealed that more of these tumors secrete abnormal levels of the stress hormone cortisol than previously thought, making them more likely to cause cardiometabolic health problems in those affected. […] Benign adrenal tumors, known as adrenal incidentalomas, are relatively common and found in up to 10% of all adults. The impact of these incidentalomas on the body varies and depends largely on whether they secrete potentially damaging hormones into the body or not. […] One hormone that incidentalomas are known to secrete is the hormone cortisol, associated with the body’s response to stress. Previous studies suggested that around a third of adrenal incidentalomas secrete cortisol, putting those affected at higher risk for developing cardiometabolic symptoms such as type 2 diabetes and high blood pressure, but according to the current study the figure could actually be closer to half of those affected.
  • #59 Benign Adrenal Tumors Linked to Hypertension, Type 2 Diabetes
    https://www.medscape.com/viewarticle/965883
    In more than 15% of people with benign adrenal tumors, the growths produce clinically relevant levels of serum cortisol that are significantly linked with an increased prevalence of hypertension and, in 5% of those with Cushing syndrome (CS), an increased prevalence of type 2 diabetes, based on data from more than 1300 people with benign adrenal tumors, the largest reported prospective study of the disorder. […] All patients found to have a benign adrenal tumor should undergo testing for MACS and have their blood pressure and glucose levels measured regularly, advised Arlt in the statement released by the University of Birmingham. […] „These data clearly support the European Society of Endocrinology guideline recommendations that clinicians should determine precisely the cardiometabolic consequences of mild cortisol secretion in patients with adrenal lesions,” writes Andr Lacroix, MD, in an accompanying editorial.
  • #60 Risk for Type 2 Diabetes, Hypertension from Benign Adrenal Tumors Higher Than Thought | Inside Precision Medicine
    https://www.insideprecisionmedicine.com/news-and-features/risk-for-type-2-diabetes-hypertension-from-benign-adrenal-tumors-higher-than-thought/
    People with benign adrenal tumors are at higher risk for type 2 diabetes and high blood pressure than previously understood, according to new research from the University of Birmingham in the U.K. […] The study, published in the Annals of Internal Medicine, revealed that more of these tumors secrete abnormal levels of the stress hormone cortisol than previously thought, making them more likely to cause cardiometabolic health problems in those affected. […] Benign adrenal tumors, known as adrenal incidentalomas, are relatively common and found in up to 10% of all adults. The impact of these incidentalomas on the body varies and depends largely on whether they secrete potentially damaging hormones into the body or not. […] One hormone that incidentalomas are known to secrete is the hormone cortisol, associated with the body’s response to stress. Previous studies suggested that around a third of adrenal incidentalomas secrete cortisol, putting those affected at higher risk for developing cardiometabolic symptoms such as type 2 diabetes and high blood pressure, but according to the current study the figure could actually be closer to half of those affected.
  • #61 Risk for Type 2 Diabetes, Hypertension from Benign Adrenal Tumors Higher Than Thought | Inside Precision Medicine
    https://www.insideprecisionmedicine.com/news-and-features/risk-for-type-2-diabetes-hypertension-from-benign-adrenal-tumors-higher-than-thought/
    Overall, almost half the participants had adrenal incidentalomas that did not secrete cortisol. Of the rest, 35% had suspected MACS and 11% had definitive MACS, with the remaining 5% diagnosed as having Cushing’s syndrome. […] High blood pressure and increased blood glucose were more common in those with definitive MACS than in those with non-cortisol secreting tumors. “Compared to those without MACS, we observed that patients with MACS were more likely to be diagnosed with high blood pressure and to require three or more tablets to achieve an adequate blood pressure control. […] Our hope is that this research will put a spotlight on this condition and increase awareness of its impact on health. We advocate that all patients who are found to carry an adrenal incidentaloma are tested for MACS and have their blood pressure and glucose levels measured regularly, added Wiebke Arlt, a professor at the University of Birmingham who led the research.
  • #62 Risk for Type 2 Diabetes, Hypertension from Benign Adrenal Tumors Higher Than Thought | Inside Precision Medicine
    https://www.insideprecisionmedicine.com/news-and-features/risk-for-type-2-diabetes-hypertension-from-benign-adrenal-tumors-higher-than-thought/
    Overall, almost half the participants had adrenal incidentalomas that did not secrete cortisol. Of the rest, 35% had suspected MACS and 11% had definitive MACS, with the remaining 5% diagnosed as having Cushing’s syndrome. […] High blood pressure and increased blood glucose were more common in those with definitive MACS than in those with non-cortisol secreting tumors. “Compared to those without MACS, we observed that patients with MACS were more likely to be diagnosed with high blood pressure and to require three or more tablets to achieve an adequate blood pressure control. […] Our hope is that this research will put a spotlight on this condition and increase awareness of its impact on health. We advocate that all patients who are found to carry an adrenal incidentaloma are tested for MACS and have their blood pressure and glucose levels measured regularly, added Wiebke Arlt, a professor at the University of Birmingham who led the research.
  • #63 Benign Adrenal Tumors Linked to Hypertension, Type 2 Diabetes
    https://www.medscape.com/viewarticle/965883
    In more than 15% of people with benign adrenal tumors, the growths produce clinically relevant levels of serum cortisol that are significantly linked with an increased prevalence of hypertension and, in 5% of those with Cushing syndrome (CS), an increased prevalence of type 2 diabetes, based on data from more than 1300 people with benign adrenal tumors, the largest reported prospective study of the disorder. […] All patients found to have a benign adrenal tumor should undergo testing for MACS and have their blood pressure and glucose levels measured regularly, advised Arlt in the statement released by the University of Birmingham. […] „These data clearly support the European Society of Endocrinology guideline recommendations that clinicians should determine precisely the cardiometabolic consequences of mild cortisol secretion in patients with adrenal lesions,” writes Andr Lacroix, MD, in an accompanying editorial.
  • #64 Benign Adrenal Tumors Linked to Hypertension, Type 2 Diabetes
    https://www.medscape.com/viewarticle/965883
    Plus, „even in patients with nonfunctioning adrenal tumors the prevalence of diabetes and hypertension is higher than in the general population, raising concerns about the cardiometabolic consequences of barely detectable cortisol excess,” writes Lacroix, an endocrinologist at the CHUM Research Center and professor of medicine at the University of Montreal, Quebec, Canada.
  • #65 Risk for Type 2 Diabetes, Hypertension from Benign Adrenal Tumors Higher Than Thought | Inside Precision Medicine
    https://www.insideprecisionmedicine.com/news-and-features/risk-for-type-2-diabetes-hypertension-from-benign-adrenal-tumors-higher-than-thought/
    Overall, almost half the participants had adrenal incidentalomas that did not secrete cortisol. Of the rest, 35% had suspected MACS and 11% had definitive MACS, with the remaining 5% diagnosed as having Cushing’s syndrome. […] High blood pressure and increased blood glucose were more common in those with definitive MACS than in those with non-cortisol secreting tumors. “Compared to those without MACS, we observed that patients with MACS were more likely to be diagnosed with high blood pressure and to require three or more tablets to achieve an adequate blood pressure control. […] Our hope is that this research will put a spotlight on this condition and increase awareness of its impact on health. We advocate that all patients who are found to carry an adrenal incidentaloma are tested for MACS and have their blood pressure and glucose levels measured regularly, added Wiebke Arlt, a professor at the University of Birmingham who led the research.
  • #66 Benign Adrenal Tumors Linked to Hypertension, Type 2 Diabetes
    https://www.medscape.com/viewarticle/965883
    In more than 15% of people with benign adrenal tumors, the growths produce clinically relevant levels of serum cortisol that are significantly linked with an increased prevalence of hypertension and, in 5% of those with Cushing syndrome (CS), an increased prevalence of type 2 diabetes, based on data from more than 1300 people with benign adrenal tumors, the largest reported prospective study of the disorder. […] All patients found to have a benign adrenal tumor should undergo testing for MACS and have their blood pressure and glucose levels measured regularly, advised Arlt in the statement released by the University of Birmingham. […] „These data clearly support the European Society of Endocrinology guideline recommendations that clinicians should determine precisely the cardiometabolic consequences of mild cortisol secretion in patients with adrenal lesions,” writes Andr Lacroix, MD, in an accompanying editorial.
  • #67 Risk for Type 2 Diabetes, Hypertension from Benign Adrenal Tumors Higher Than Thought | Inside Precision Medicine
    https://www.insideprecisionmedicine.com/news-and-features/risk-for-type-2-diabetes-hypertension-from-benign-adrenal-tumors-higher-than-thought/
    The research team points out that up to 1.3 million adults in the U.K. alone could have MACS. They think faster diagnosis of this condition could help many people, particularly post-menopausal women, get the treatment they need or make earlier lifestyle adjustments to avoid developing type 2 diabetes or experiencing more advanced cardiovascular disease.
  • #68 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Adrenal adenomas are benign neoplasms that originate from the adrenal cortex. They can be categorized as either nonsecreting or functional. Nonfunctional adenomas and those with mild hormonal secretion may not produce noticeable symptoms and can remain asymptomatic. However, adenomas that exhibit significant hormonal activity often present with characteristic symptoms of Cushing syndrome, primary hyperaldosteronism, or hyperandrogenism. […] Overall, the prognosis for patients with adrenal adenomas is excellent if the condition is promptly diagnosed and treated. The complication rate is generally low. This activity aims to review the evaluation and management of adrenal adenomas and emphasizes the roles of the healthcare team in caring for patients with this condition. […] Unilateral adrenalectomy is the preferred treatment for adenomas larger than 4 cm, which are suspected to be malignant, or any hormonally active adenomas that show biochemical evidence of Cushing syndrome or primary hyperaldosteronism.
  • #69 Benign adrenal tumors – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/benign-adrenal-tumors/diagnosis-treatment/drc-20567035
    Benign adrenal tumors often are found by chance on imaging that’s done for another reason. A healthcare professional then looks at how likely the tumor is to be cancer and whether it’s making too much hormone. […] Our caring team of Mayo Clinic experts can help you with your benign adrenal tumors-related health concerns. […] Benign adrenal tumors often don’t need treatment. Treatment depends on how likely the tumor is to become cancer. Treatment also might depend on whether the tumor is making hormones, the type of hormone it makes and how much it’s making. […] Treatment for small benign adrenal tumors that aren’t making hormones might involve watching the tumor. There might be repeat imaging tests 3 to 6 months after diagnosis, and then every one or two years. Watching also might involve testing hormones every year for five years.
  • #70 Adrenal Adenoma – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK539906/
    Adrenal adenomas are benign neoplasms that originate from the adrenal cortex. They can be categorized as either nonsecreting or functional. Nonfunctional adenomas and those with mild hormonal secretion may not produce noticeable symptoms and can remain asymptomatic. However, adenomas that exhibit significant hormonal activity often present with characteristic symptoms of Cushing syndrome, primary hyperaldosteronism, or hyperandrogenism. […] Overall, the prognosis for patients with adrenal adenomas is excellent if the condition is promptly diagnosed and treated. The complication rate is generally low. This activity aims to review the evaluation and management of adrenal adenomas and emphasizes the roles of the healthcare team in caring for patients with this condition. […] Unilateral adrenalectomy is the preferred treatment for adenomas larger than 4 cm, which are suspected to be malignant, or any hormonally active adenomas that show biochemical evidence of Cushing syndrome or primary hyperaldosteronism.
  • #71 What Are Benign Adrenal Tumors?
    https://www.icliniq.com/articles/endocrine-diseases/benign-adrenal-tumors
    Benign adrenal tumors are noncancerous masses occurring in the adrenal glands. These tumors can cause systemic problems. […] Most benign adrenal tumors are asymptomatic and do not cause much harm to the body; therefore, they do not require any treatment. Whereas some benign adrenal tumors are functioning or active, which means they overproduce the adrenal hormones and cause systemic problems, and in this case, they are symptomatic and require immediate treatment. […] Benign adrenal tumors that are non-functioning and asymptomatic generally do not require any treatment. However, they do need to follow up with their healthcare provider to check whether the size of the tumor is increasing or if it has started producing hormones. Functioning benign adrenal tumors require immediate treatment, and they are typically treated with surgery. Hormone therapy, chemotherapy, or radionuclide therapy are also sometimes used to treat the condition. […] The diagnosis and treatment of the condition are effective, and the prognosis of the treatment of these tumors is excellent.