Materiały źródłowe

• #1

  https://winshipcancer.emory.edu/cancer-types-and-treatments/lymphoma/prevention.php

  There is no guaranteed way to prevent lymphoma. And while the causes of Hodgkin and non-Hodgkin lymphoma are still being studied, you can lower your risk of getting the disease. […] Because lymphoma affects your immune system, there are steps you can take to prevent it, such as limiting your risk of contracting infections and making lifestyle changes that help you maintain a healthy immune system. You can also reduce your risk if you: […] Besides researching new therapies for treating lymphoma, Winship Cancer Institute is also collaborating on a study to determine how to prevent non-Hodgkin lymphoma.

• #2 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  There is no sure way to prevent non-Hodgkin lymphoma (NHL). But there are some things you can do that might help lower your risk. […] Most people with NHL have no risk factors that can be changed, so there is no way to protect against these lymphomas. But you may be able to lower your risk by limiting your risk of certain infections and doing what you can to maintain a healthy immune system. […] Infection with HIV, the virus that causes AIDS, is known to increase the risk of NHL, so one way to limit your risk is to avoid known risk factors for HIV, such as intravenous drug use or unprotected sex with many partners. […] Preventing the spread of the human T-cell lymphotropic virus (HTLV-1) could have a great impact on non-Hodgkin lymphoma in areas of the world where this virus is common, such as Japan and the Caribbean region.

• #3 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  Unfortunately, there is no decisive answer on how to prevent lymphoma. The main reason for this is that we do not have complete information about the exact causes of lymphoma. […] However, understanding lymphoma risk factors can play a significant role in reducing the chances of developing lymphoma. […] Though there are no definitive ways of preventing lymphoma, adopting certain measures can surely help reduce the risk of developing cancer. […] Smoking can have an adverse effect on the genetics of healthy cells, increasing the chances of cancer development. Thus, it is recommended to quit smoking as a potential lymphoma cancer prevention strategy. […] A potential lymphoma prevention diet should include a balance of fruits, whole grains, and nuts while limiting the intake of processed meats and sugary drinks.

• #4 Non-Hodgkin’s Lymphoma Risk Factors and Prevention Measures

  https://www.hcgoncology.com/types-of-cancers/non-hodgkins-lymphoma-prevention/

  Maintaining a healthy weight is a crucial non-Hodgkins lymphoma prevention measure. Obesity has been associated with an increased risk of certain lymphomas, and adopting a lifestyle that includes balanced nutrition and regular physical activity contributes to overall well-being and lowers the risk of lymphoma development. […] Engaging in regular physical activity not only promotes cardiovascular health but also plays a role in non-Hodgkins lymphoma prevention. Exercise boosts the immune system, reduces inflammation, and contributes to weight management, all of which are key factors in lowering the risk of non-Hodgkin’s lymphoma. […] Adopting a nutritious diet rich in fruits, vegetables, whole grains, and lean proteins is also an important non-Hodgkin’s lymphoma prevention measure. Antioxidant-rich foods contribute to overall health and may help protect against cellular damage that can lead to lymphoma. A well-balanced diet supports the body’s immune system and aids in maintaining optimal health. […] Adopting appropriate preventive strategies can, however, reduce ones chances of developing non-Hodgkins lymphoma. […] Understanding and managing these viral infections are crucial aspects of preventive care.

• #5 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  Thus, maintaining a healthy weight can go a long way toward possible lymphoma prevention. […] Staying physically active while exercising regularly is also considered effective in reducing the risk of developing lymphoma. […] Though there are no sure ways to prevent lymphoma, taking care of its risk factors can surely help reduce its development.

• #6 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  Helicobacter pylori (H. pylori) infection has been linked to some lymphomas of the stomach. Treating H. pylori infections with antibiotics and antacids may lower this risk, but the benefit of this strategy has not been proven yet. […] Some studies have suggested that having excess body weight may increase your risk of non-Hodgkin lymphoma. Staying at a healthy weight, keeping physically active, and following a healthy eating pattern that includes plenty of fruits, vegetables, and whole grains, and that limits or avoids red and processed meats, sugary drinks, and highly processed foods may help protect against lymphoma, but more research is needed to confirm this.

• #7 Lymphoma | Nutrition Guide for Clinicians

  https://nutritionguide.pcrm.org/nutritionguide/view/Nutrition_Guide_for_Clinicians/1342083/all/Lymphoma

  Increasing intake of fruits and vegetables. When the highest category of fruit and vegetable intake was compared with the lowest, a meta-analysis found a roughly 20% lower risk for NHL in high consumers, a difference that appeared to be due mainly to vegetable rather than fruit intake. […] High vitamin A and C intakes. The observed benefits of fruits and vegetables in relation to lymphoma prevention may be in part attributable to vitamin C and pro-vitamin A carotenoids. […] A gluten-free diet for individuals with celiac disease. Patients with celiac disease have a 25% greater risk for malignancy overall, a 60% greater risk for gastrointestinal malignancy, a 14 times greater risk for small intestine carcinoma, and a 6-9 times greater risk for NHL when compared with the general population. […] Maintenance of a healthy weight. Studies suggest that being significantly overweight or obese may increase the risk for lymphomas.

• #8 Non Hodgkin’s Lymphoma Prevention Strategies – Acibadem Health Point – ACIBADEM Hospitals – Acibadem Health Group

  https://www.acibademhealthpoint.com/non-hodgkins-lymphoma-prevention-strategies/

  Adding different fruits and veggies to each meal is smart. They give you important vitamins, minerals, and antioxidants. These help your immune system and keep you healthy. Try to eat fruits and veggies of all colors. This way, you get many nutrients. This helps lower the chance of getting cancer. […] Doing tasks that make us move is very good for our health. It lowers the chance of getting non Hodgkin’s lymphoma. When we exercise, we get more fit and our immune system stays strong. This helps to lower the risk of lymphoma. […] Finding lymphoma early is very important. Knowing the symptoms helps a lot. Symptoms like losing weight for no reason, swollen lymph nodes, and feeling tired all the time should not be ignored. Knowing these signs early can help you get to the doctor sooner. […] A good night’s sleep and how we handle stress are key to a strong immune system. They help us stay healthy and fight off diseases like non Hodgkin’s lymphoma.

• #9 Lymphoma | Nutrition Guide for Clinicians

  https://nutritionguide.pcrm.org/nutritionguide/view/Nutrition_Guide_for_Clinicians/1342083/all/Lymphoma

  Lymphoma is a complex group of more than 40 subtypes with widely differing treatments and prognoses. In general, lymphomas are highly treatable, and most patients survive beyond 5 years. Limited evidence suggests that low-fat, plant-based diets may reduce the risk of this disease. It is not yet known whether dietary factors can influence its course. […] A limited number of studies have addressed associations between diet and risk for lymphoma. The following factors have been under study for possible roles in reducing risk: […] Reducing or avoiding intake of animal products. A meta-analysis concluded that individuals eating the most red meat had a 10% greater risk of NHL when compared with those eating the least, and for diffuse B-cell lymphoma, this risk increased to 20%. […] Reducing intake of saturated fat and trans fats. One case-control study revealed that high saturated fat intake is significantly associated with Hodgkin lymphoma.

• #10 Lymphoma | Nutrition Guide for Clinicians

  https://nutritionguide.pcrm.org/nutritionguide/view/Nutrition_Guide_for_Clinicians/1342083/all/Lymphoma

  Increasing intake of fruits and vegetables. When the highest category of fruit and vegetable intake was compared with the lowest, a meta-analysis found a roughly 20% lower risk for NHL in high consumers, a difference that appeared to be due mainly to vegetable rather than fruit intake. […] High vitamin A and C intakes. The observed benefits of fruits and vegetables in relation to lymphoma prevention may be in part attributable to vitamin C and pro-vitamin A carotenoids. […] A gluten-free diet for individuals with celiac disease. Patients with celiac disease have a 25% greater risk for malignancy overall, a 60% greater risk for gastrointestinal malignancy, a 14 times greater risk for small intestine carcinoma, and a 6-9 times greater risk for NHL when compared with the general population. […] Maintenance of a healthy weight. Studies suggest that being significantly overweight or obese may increase the risk for lymphomas.

• #11 Lymphoma | Nutrition Guide for Clinicians

  https://nutritionguide.pcrm.org/nutritionguide/view/Nutrition_Guide_for_Clinicians/1342083/all/Lymphoma

  Increasing intake of fruits and vegetables. When the highest category of fruit and vegetable intake was compared with the lowest, a meta-analysis found a roughly 20% lower risk for NHL in high consumers, a difference that appeared to be due mainly to vegetable rather than fruit intake. […] High vitamin A and C intakes. The observed benefits of fruits and vegetables in relation to lymphoma prevention may be in part attributable to vitamin C and pro-vitamin A carotenoids. […] A gluten-free diet for individuals with celiac disease. Patients with celiac disease have a 25% greater risk for malignancy overall, a 60% greater risk for gastrointestinal malignancy, a 14 times greater risk for small intestine carcinoma, and a 6-9 times greater risk for NHL when compared with the general population. […] Maintenance of a healthy weight. Studies suggest that being significantly overweight or obese may increase the risk for lymphomas.

• #12 Hodgkin Lymphoma Screening/Prevention | Nebraska Hematology Oncology – Cancer Care Treatment Blood Disorders Clinical Trials Lincoln Nebraska (NE)

  https://www.yourcancercare.com/types-of-cancer/hodgkin-lymphoma/hodgkin-lymphoma-screeningprevention

  A poor diet is a fertile area for immediate individual and societal intervention to decrease the risk of developing certain cancers. Numerous studies have provided a wealth of information about the detrimental and protective factors of different foods. […] Higher levels of physical activity may reduce the incidence of some cancers. According to researchers at Harvard, if the entire population increased their level of physical activity by 30 minutes of brisk walking per day (or the equivalent energy expenditure in other activities), we would observe a 15% reduction in the incidence of colon cancer. […] For many types of cancer, progress in the areas of cancer screening and treatment has offered promise for earlier detection and higher cure rates. The term screening refers to the regular use of certain examinations or tests in persons who do not have any symptoms of a cancer but are at high risk for that cancer.

• #13 Lymphoma: Symptoms, Causes, Types, Diagnosis & Treatment PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact Number f

  https://www.pacehospital.com/lymphoma-symptoms-causes-types-diagnosis-treatment

  There is no proven way of preventing lymphoma but as lymphoma affects the immune system, there are steps that can be taken to prevent it, such as reducing the risk of contracting infections and making lifestyle changes which helps in maintaining a healthy immune system. The following are some of the measures to reduce the risk of lymphoma: […] Physical activity: It is important for both the physical and mental health of the individual. It reduces fatigue and increases muscle strength and improves balance. […] Diet: Including diets rich in fruits, vegetables, and whole grains reduces the risk of developing lymphoma. Avoiding foods such as processed meat and high energy foods can improve health. […] Avoiding smoking: Smoking is one of the potential risk factors for developing lymphoma. Therefore, smoking cessation can reduce the risk of developing late effects after treatment.

• #14 Non-Hodgkin’s Lymphoma Risk Factors and Prevention Measures

  https://www.hcgoncology.com/types-of-cancers/non-hodgkins-lymphoma-prevention/

  Maintaining a healthy weight is a crucial non-Hodgkins lymphoma prevention measure. Obesity has been associated with an increased risk of certain lymphomas, and adopting a lifestyle that includes balanced nutrition and regular physical activity contributes to overall well-being and lowers the risk of lymphoma development. […] Engaging in regular physical activity not only promotes cardiovascular health but also plays a role in non-Hodgkins lymphoma prevention. Exercise boosts the immune system, reduces inflammation, and contributes to weight management, all of which are key factors in lowering the risk of non-Hodgkin’s lymphoma. […] Adopting a nutritious diet rich in fruits, vegetables, whole grains, and lean proteins is also an important non-Hodgkin’s lymphoma prevention measure. Antioxidant-rich foods contribute to overall health and may help protect against cellular damage that can lead to lymphoma. A well-balanced diet supports the body’s immune system and aids in maintaining optimal health. […] Adopting appropriate preventive strategies can, however, reduce ones chances of developing non-Hodgkins lymphoma. […] Understanding and managing these viral infections are crucial aspects of preventive care.

• #15 Hodgkin Lymphoma Screening/Prevention | Nebraska Hematology Oncology – Cancer Care Treatment Blood Disorders Clinical Trials Lincoln Nebraska (NE)

  https://www.yourcancercare.com/types-of-cancer/hodgkin-lymphoma/hodgkin-lymphoma-screeningprevention

  A poor diet is a fertile area for immediate individual and societal intervention to decrease the risk of developing certain cancers. Numerous studies have provided a wealth of information about the detrimental and protective factors of different foods. […] Higher levels of physical activity may reduce the incidence of some cancers. According to researchers at Harvard, if the entire population increased their level of physical activity by 30 minutes of brisk walking per day (or the equivalent energy expenditure in other activities), we would observe a 15% reduction in the incidence of colon cancer. […] For many types of cancer, progress in the areas of cancer screening and treatment has offered promise for earlier detection and higher cure rates. The term screening refers to the regular use of certain examinations or tests in persons who do not have any symptoms of a cancer but are at high risk for that cancer.

• #16 Lymphoma: Symptoms, Causes, Types, Diagnosis & Treatment PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact Number f

  https://www.pacehospital.com/lymphoma-symptoms-causes-types-diagnosis-treatment

  There is no proven way of preventing lymphoma but as lymphoma affects the immune system, there are steps that can be taken to prevent it, such as reducing the risk of contracting infections and making lifestyle changes which helps in maintaining a healthy immune system. The following are some of the measures to reduce the risk of lymphoma: […] Physical activity: It is important for both the physical and mental health of the individual. It reduces fatigue and increases muscle strength and improves balance. […] Diet: Including diets rich in fruits, vegetables, and whole grains reduces the risk of developing lymphoma. Avoiding foods such as processed meat and high energy foods can improve health. […] Avoiding smoking: Smoking is one of the potential risk factors for developing lymphoma. Therefore, smoking cessation can reduce the risk of developing late effects after treatment.

• #17 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  Helicobacter pylori (H. pylori) infection has been linked to some lymphomas of the stomach. Treating H. pylori infections with antibiotics and antacids may lower this risk, but the benefit of this strategy has not been proven yet. […] Some studies have suggested that having excess body weight may increase your risk of non-Hodgkin lymphoma. Staying at a healthy weight, keeping physically active, and following a healthy eating pattern that includes plenty of fruits, vegetables, and whole grains, and that limits or avoids red and processed meats, sugary drinks, and highly processed foods may help protect against lymphoma, but more research is needed to confirm this.

• #18 Lymphoma | Nutrition Guide for Clinicians

  https://nutritionguide.pcrm.org/nutritionguide/view/Nutrition_Guide_for_Clinicians/1342083/all/Lymphoma

  Increasing intake of fruits and vegetables. When the highest category of fruit and vegetable intake was compared with the lowest, a meta-analysis found a roughly 20% lower risk for NHL in high consumers, a difference that appeared to be due mainly to vegetable rather than fruit intake. […] High vitamin A and C intakes. The observed benefits of fruits and vegetables in relation to lymphoma prevention may be in part attributable to vitamin C and pro-vitamin A carotenoids. […] A gluten-free diet for individuals with celiac disease. Patients with celiac disease have a 25% greater risk for malignancy overall, a 60% greater risk for gastrointestinal malignancy, a 14 times greater risk for small intestine carcinoma, and a 6-9 times greater risk for NHL when compared with the general population. […] Maintenance of a healthy weight. Studies suggest that being significantly overweight or obese may increase the risk for lymphomas.

• #19 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  Thus, maintaining a healthy weight can go a long way toward possible lymphoma prevention. […] Staying physically active while exercising regularly is also considered effective in reducing the risk of developing lymphoma. […] Though there are no sure ways to prevent lymphoma, taking care of its risk factors can surely help reduce its development.

• #20 Lymphoma: Symptoms, Causes, Types, Diagnosis & Treatment PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact Number f

  https://www.pacehospital.com/lymphoma-symptoms-causes-types-diagnosis-treatment

  Maintaining body weight: Maintaining a healthy weight is a part of leading a healthy lifestyle. To reach a healthy weight, people need to reduce food consumption and increase physical activity. Reducing daily calorie intake trying to decrease portion size at every meal and limiting the number of snacks throughout the day. […] Avoiding contracting infections: Avoiding known risk factors for HIV, such as intravenous drug use or unprotected sex with multiple partners can reduce the risk of contracting infections.

• #21 Non-Hodgkin’s Lymphoma Risk Factors and Prevention Measures

  https://www.hcgoncology.com/types-of-cancers/non-hodgkins-lymphoma-prevention/

  Maintaining a healthy weight is a crucial non-Hodgkins lymphoma prevention measure. Obesity has been associated with an increased risk of certain lymphomas, and adopting a lifestyle that includes balanced nutrition and regular physical activity contributes to overall well-being and lowers the risk of lymphoma development. […] Engaging in regular physical activity not only promotes cardiovascular health but also plays a role in non-Hodgkins lymphoma prevention. Exercise boosts the immune system, reduces inflammation, and contributes to weight management, all of which are key factors in lowering the risk of non-Hodgkin’s lymphoma. […] Adopting a nutritious diet rich in fruits, vegetables, whole grains, and lean proteins is also an important non-Hodgkin’s lymphoma prevention measure. Antioxidant-rich foods contribute to overall health and may help protect against cellular damage that can lead to lymphoma. A well-balanced diet supports the body’s immune system and aids in maintaining optimal health. […] Adopting appropriate preventive strategies can, however, reduce ones chances of developing non-Hodgkins lymphoma. […] Understanding and managing these viral infections are crucial aspects of preventive care.

• #22 Reducing your risk for non-Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/non-hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing non-Hodgkin lymphoma (NHL) by doing the following. […] Avoid or lower your long-term exposure to pesticides. […] You may lower your risk by having a healthy body weight. […] Follow occupational and safety guidelines when working with hazardous chemicals. […] Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for NHL.

• #23 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  Unfortunately, there is no decisive answer on how to prevent lymphoma. The main reason for this is that we do not have complete information about the exact causes of lymphoma. […] However, understanding lymphoma risk factors can play a significant role in reducing the chances of developing lymphoma. […] Though there are no definitive ways of preventing lymphoma, adopting certain measures can surely help reduce the risk of developing cancer. […] Smoking can have an adverse effect on the genetics of healthy cells, increasing the chances of cancer development. Thus, it is recommended to quit smoking as a potential lymphoma cancer prevention strategy. […] A potential lymphoma prevention diet should include a balance of fruits, whole grains, and nuts while limiting the intake of processed meats and sugary drinks.

• #24 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  As excessive alcohol consumption can weaken an individual’s immune system, it is recommended to limit its consumption to reduce the risk of lymphoma. […] Certain infections associated with lymphoma, such as Epstein-Barr virus or Hepatitis C virus (HCV), can hamper the healthy DNA of the cells; treating them can help in potential lymphoma prevention as well. […] Minimizing excessive exposure to toxic chemicals, such as benzene, can also help reduce the risk of developing lymphoma. […] As radiation exposure can damage the DNA structure of healthy cells, leading to an increased risk of lymphoma, it is often recommended to limit radiation exposure as much as possible. […] As lymphoma affects the lymphatic system, an important part of the immune system, experts advise making efforts to maintain a healthy immune system for potential lymphoma prevention.

• #25 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  Unfortunately, there is no decisive answer on how to prevent lymphoma. The main reason for this is that we do not have complete information about the exact causes of lymphoma. […] However, understanding lymphoma risk factors can play a significant role in reducing the chances of developing lymphoma. […] Though there are no definitive ways of preventing lymphoma, adopting certain measures can surely help reduce the risk of developing cancer. […] Smoking can have an adverse effect on the genetics of healthy cells, increasing the chances of cancer development. Thus, it is recommended to quit smoking as a potential lymphoma cancer prevention strategy. […] A potential lymphoma prevention diet should include a balance of fruits, whole grains, and nuts while limiting the intake of processed meats and sugary drinks.

• #26 Reducing your risk for Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing Hodgkin lymphoma (HL) by doing the following. […] You can lower your risk of getting HIV infection by avoiding activities that are known to increase the risk of HIV, such as intravenous drug use or having sex without a condom with many partners. […] To help reduce the risk of Epstein-Barr virus (EBV) infection, dont share drinks, food, utensils or toothbrushes. […] Smoking tobacco may increase your risk of developing HL. If you smoke, get help to quit. […] Some people can have a higher than average risk for HL. Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for HL. Your doctor will recommend what tests you should have and how often you should have them. […] Learn how cancer can be prevented and what you can do to reduce your risk.

• #27 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  As excessive alcohol consumption can weaken an individual’s immune system, it is recommended to limit its consumption to reduce the risk of lymphoma. […] Certain infections associated with lymphoma, such as Epstein-Barr virus or Hepatitis C virus (HCV), can hamper the healthy DNA of the cells; treating them can help in potential lymphoma prevention as well. […] Minimizing excessive exposure to toxic chemicals, such as benzene, can also help reduce the risk of developing lymphoma. […] As radiation exposure can damage the DNA structure of healthy cells, leading to an increased risk of lymphoma, it is often recommended to limit radiation exposure as much as possible. […] As lymphoma affects the lymphatic system, an important part of the immune system, experts advise making efforts to maintain a healthy immune system for potential lymphoma prevention.

• #28 Non Hodgkin’s Lymphoma Prevention Strategies – Acibadem Health Point – ACIBADEM Hospitals – Acibadem Health Group

  https://www.acibademhealthpoint.com/non-hodgkins-lymphoma-prevention-strategies/

  Non Hodgkin’s Lymphoma Prevention Strategies It’s really important to know and use the best non Hodgkin’s lymphoma prevention tips. This helps lower the chances of getting this type of cancer. A big plan includes changing your lifestyle, what you eat, and getting checked by the doctor often. […] Changing our lifestyles is key to dodge non Hodgkin’s lymphoma. Big health groups say stop smoking, drink less, and avoid bad chemicals like pesticides. […] One big way to dodge lymphoma is by quitting smoking. The World Health Organization warns smoking leads to many cancers, lymphoma included. Stopping smoking helps a lot and boosts your health overall. […] The Centers for Disease Control and Prevention says drinking less can help stop lymphoma. Too much alcohol bumps up cancer risks. Keeping within safe drink limits cuts your chances of getting lymphoma.

• #29 Non Hodgkin’s Lymphoma Prevention Strategies – Acibadem Health Point – ACIBADEM Hospitals – Acibadem Health Group

  https://www.acibademhealthpoint.com/non-hodgkins-lymphoma-prevention-strategies/

  Non Hodgkin’s Lymphoma Prevention Strategies It’s really important to know and use the best non Hodgkin’s lymphoma prevention tips. This helps lower the chances of getting this type of cancer. A big plan includes changing your lifestyle, what you eat, and getting checked by the doctor often. […] Changing our lifestyles is key to dodge non Hodgkin’s lymphoma. Big health groups say stop smoking, drink less, and avoid bad chemicals like pesticides. […] One big way to dodge lymphoma is by quitting smoking. The World Health Organization warns smoking leads to many cancers, lymphoma included. Stopping smoking helps a lot and boosts your health overall. […] The Centers for Disease Control and Prevention says drinking less can help stop lymphoma. Too much alcohol bumps up cancer risks. Keeping within safe drink limits cuts your chances of getting lymphoma.

• #30 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  There is no sure way to prevent non-Hodgkin lymphoma (NHL). But there are some things you can do that might help lower your risk. […] Most people with NHL have no risk factors that can be changed, so there is no way to protect against these lymphomas. But you may be able to lower your risk by limiting your risk of certain infections and doing what you can to maintain a healthy immune system. […] Infection with HIV, the virus that causes AIDS, is known to increase the risk of NHL, so one way to limit your risk is to avoid known risk factors for HIV, such as intravenous drug use or unprotected sex with many partners. […] Preventing the spread of the human T-cell lymphotropic virus (HTLV-1) could have a great impact on non-Hodgkin lymphoma in areas of the world where this virus is common, such as Japan and the Caribbean region.

• #31 Can I Prevent Lymphoma? (Risk Factors & Prevention Tips)

  https://islandhospital.com/how-to-prevent-lymphoma/

  Limit exposure to harmful substances. Some chemicals, pesticides, and radiation have been linked to an increased risk of lymphoma. It is important to follow safety guidelines in occupational settings. […] Protect against infections. Practise good hygiene and get recommended vaccinations to reduce the risk of infections that could increase your lymphoma risk. […] Therefore, effectively managing these infections may play a role in preventing lymphoma. […] Practising safe sexual behaviours, undergoing regular HIV testing, and adhering to treatment regimens if infected are essential steps in reducing the risk of both HIV and lymphoma.

• #32 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  There is no sure way to prevent non-Hodgkin lymphoma (NHL). But there are some things you can do that might help lower your risk. […] Most people with NHL have no risk factors that can be changed, so there is no way to protect against these lymphomas. But you may be able to lower your risk by limiting your risk of certain infections and doing what you can to maintain a healthy immune system. […] Infection with HIV, the virus that causes AIDS, is known to increase the risk of NHL, so one way to limit your risk is to avoid known risk factors for HIV, such as intravenous drug use or unprotected sex with many partners. […] Preventing the spread of the human T-cell lymphotropic virus (HTLV-1) could have a great impact on non-Hodgkin lymphoma in areas of the world where this virus is common, such as Japan and the Caribbean region.

• #33 Non-Hodgkin’s Lymphoma Risk Factors and Prevention Measures

  https://www.hcgoncology.com/types-of-cancers/non-hodgkins-lymphoma-prevention/

  Non-Hodgkins lymphoma risk factors refer to those that increase ones chances of developing non-Hodgkins lymphoma. Learning about the different risk factors of NHL helps devise appropriate non-Hodgkins lymphoma prevention strategies. […] Learning about the different risk factors can help in devising the appropriate non-Hodgkins lymphoma prevention measures. These measures do not prevent the disease; however, they help reducing its risk to some extent. The following are the important non-Hodgkins lymphoma prevention measures: […] One of the important non-Hodgkin’s lymphoma prevention measures involves managing infections like HIV and hepatitis C. Timely diagnosis and treatment of these viral infections can reduce the risk of developing lymphomas associated with weakened immune systems, emphasizing the importance of regular screenings and antiviral therapies.

• #34 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  There is no sure way to prevent non-Hodgkin lymphoma (NHL). But there are some things you can do that might help lower your risk. […] Most people with NHL have no risk factors that can be changed, so there is no way to protect against these lymphomas. But you may be able to lower your risk by limiting your risk of certain infections and doing what you can to maintain a healthy immune system. […] Infection with HIV, the virus that causes AIDS, is known to increase the risk of NHL, so one way to limit your risk is to avoid known risk factors for HIV, such as intravenous drug use or unprotected sex with many partners. […] Preventing the spread of the human T-cell lymphotropic virus (HTLV-1) could have a great impact on non-Hodgkin lymphoma in areas of the world where this virus is common, such as Japan and the Caribbean region.

• #35 Reducing your risk for Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing Hodgkin lymphoma (HL) by doing the following. […] You can lower your risk of getting HIV infection by avoiding activities that are known to increase the risk of HIV, such as intravenous drug use or having sex without a condom with many partners. […] To help reduce the risk of Epstein-Barr virus (EBV) infection, dont share drinks, food, utensils or toothbrushes. […] Smoking tobacco may increase your risk of developing HL. If you smoke, get help to quit. […] Some people can have a higher than average risk for HL. Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for HL. Your doctor will recommend what tests you should have and how often you should have them. […] Learn how cancer can be prevented and what you can do to reduce your risk.

• #36 Non-Hodgkin’s Lymphoma: Symptoms, Causes, and More

  https://www.healthline.com/health/non-hodgkins-lymphoma

  Theres no known way to prevent NHL. It may be possible to lower your risk for the condition by avoiding known risk factors such as obesity and HIV: […] Using barrier methods each time you engage in sexual activity can lower your chances of contracting HIV. […] Avoiding intravenous drug use or using clean needles when injecting drugs can lower your chances of contracting HIV or hepatitis C. […] The following actions can help prevent obesity and may protect against lymphoma: staying at a moderate weight, keeping physically active, following a nutritious diet with lots of fruit, vegetables, and whole grains, and limited sugary drinks, red or processed meats, and highly processed foods. […] However, some important risk factors, such as age and family history, are fixed and cant be changed.

• #37 Can I Prevent Lymphoma? (Risk Factors & Prevention Tips)

  https://islandhospital.com/how-to-prevent-lymphoma/

  Limit exposure to harmful substances. Some chemicals, pesticides, and radiation have been linked to an increased risk of lymphoma. It is important to follow safety guidelines in occupational settings. […] Protect against infections. Practise good hygiene and get recommended vaccinations to reduce the risk of infections that could increase your lymphoma risk. […] Therefore, effectively managing these infections may play a role in preventing lymphoma. […] Practising safe sexual behaviours, undergoing regular HIV testing, and adhering to treatment regimens if infected are essential steps in reducing the risk of both HIV and lymphoma.

• #38

  https://www.acco.org/blog/risk-factors-causes-and-prevention-of-non-hodgkin-lymphoma-in-children/

  There is a simple answer to this critical question: no. Most children diagnosed with non-Hodgkin lymphoma have no risk factors or lifestyle issues that could have been altered or changed in any way to prevent the development of this disease. […] While it is entirely natural and very common to search for a cause or something to blame when a child is diagnosed with NHL (or any type of cancer), it is important that parents and guardians understand that there is nothing that they could have done differently to prevent this disease. […] There are two notable exceptions. First, a small percentage of diagnoses are associated with a compromised immune system such as HIV infection. HIV-positive mothers are encouraged to take active steps during and after pregnancy to reduce the risk of passing HIV along to their children. Second, NHL may develop as a second cancer stemming from a prior cancer treatment or immune-suppressing drugs taken to facilitate an organ transplant.

• #39 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  There is no sure way to prevent non-Hodgkin lymphoma (NHL). But there are some things you can do that might help lower your risk. […] Most people with NHL have no risk factors that can be changed, so there is no way to protect against these lymphomas. But you may be able to lower your risk by limiting your risk of certain infections and doing what you can to maintain a healthy immune system. […] Infection with HIV, the virus that causes AIDS, is known to increase the risk of NHL, so one way to limit your risk is to avoid known risk factors for HIV, such as intravenous drug use or unprotected sex with many partners. […] Preventing the spread of the human T-cell lymphotropic virus (HTLV-1) could have a great impact on non-Hodgkin lymphoma in areas of the world where this virus is common, such as Japan and the Caribbean region.

• #40 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  As excessive alcohol consumption can weaken an individual’s immune system, it is recommended to limit its consumption to reduce the risk of lymphoma. […] Certain infections associated with lymphoma, such as Epstein-Barr virus or Hepatitis C virus (HCV), can hamper the healthy DNA of the cells; treating them can help in potential lymphoma prevention as well. […] Minimizing excessive exposure to toxic chemicals, such as benzene, can also help reduce the risk of developing lymphoma. […] As radiation exposure can damage the DNA structure of healthy cells, leading to an increased risk of lymphoma, it is often recommended to limit radiation exposure as much as possible. […] As lymphoma affects the lymphatic system, an important part of the immune system, experts advise making efforts to maintain a healthy immune system for potential lymphoma prevention.

• #41 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  There is no sure way to prevent non-Hodgkin lymphoma (NHL). But there are some things you can do that might help lower your risk. […] Most people with NHL have no risk factors that can be changed, so there is no way to protect against these lymphomas. But you may be able to lower your risk by limiting your risk of certain infections and doing what you can to maintain a healthy immune system. […] Infection with HIV, the virus that causes AIDS, is known to increase the risk of NHL, so one way to limit your risk is to avoid known risk factors for HIV, such as intravenous drug use or unprotected sex with many partners. […] Preventing the spread of the human T-cell lymphotropic virus (HTLV-1) could have a great impact on non-Hodgkin lymphoma in areas of the world where this virus is common, such as Japan and the Caribbean region.

• #42 Reducing your risk for Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing Hodgkin lymphoma (HL) by doing the following. […] You can lower your risk of getting HIV infection by avoiding activities that are known to increase the risk of HIV, such as intravenous drug use or having sex without a condom with many partners. […] To help reduce the risk of Epstein-Barr virus (EBV) infection, dont share drinks, food, utensils or toothbrushes. […] Smoking tobacco may increase your risk of developing HL. If you smoke, get help to quit. […] Some people can have a higher than average risk for HL. Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for HL. Your doctor will recommend what tests you should have and how often you should have them. […] Learn how cancer can be prevented and what you can do to reduce your risk.

• #43 Can I Prevent Lymphoma? (Risk Factors & Prevention Tips)

  https://islandhospital.com/how-to-prevent-lymphoma/

  Limit exposure to harmful substances. Some chemicals, pesticides, and radiation have been linked to an increased risk of lymphoma. It is important to follow safety guidelines in occupational settings. […] Protect against infections. Practise good hygiene and get recommended vaccinations to reduce the risk of infections that could increase your lymphoma risk. […] Therefore, effectively managing these infections may play a role in preventing lymphoma. […] Practising safe sexual behaviours, undergoing regular HIV testing, and adhering to treatment regimens if infected are essential steps in reducing the risk of both HIV and lymphoma.

• #44 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  Helicobacter pylori (H. pylori) infection has been linked to some lymphomas of the stomach. Treating H. pylori infections with antibiotics and antacids may lower this risk, but the benefit of this strategy has not been proven yet. […] Some studies have suggested that having excess body weight may increase your risk of non-Hodgkin lymphoma. Staying at a healthy weight, keeping physically active, and following a healthy eating pattern that includes plenty of fruits, vegetables, and whole grains, and that limits or avoids red and processed meats, sugary drinks, and highly processed foods may help protect against lymphoma, but more research is needed to confirm this.

• #45 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  Helicobacter pylori (H. pylori) infection has been linked to some lymphomas of the stomach. Treating H. pylori infections with antibiotics and antacids may lower this risk, but the benefit of this strategy has not been proven yet. […] Some studies have suggested that having excess body weight may increase your risk of non-Hodgkin lymphoma. Staying at a healthy weight, keeping physically active, and following a healthy eating pattern that includes plenty of fruits, vegetables, and whole grains, and that limits or avoids red and processed meats, sugary drinks, and highly processed foods may help protect against lymphoma, but more research is needed to confirm this.

• #46 Can I Prevent Lymphoma? (Risk Factors & Prevention Tips)

  https://islandhospital.com/how-to-prevent-lymphoma/

  Limit exposure to harmful substances. Some chemicals, pesticides, and radiation have been linked to an increased risk of lymphoma. It is important to follow safety guidelines in occupational settings. […] Protect against infections. Practise good hygiene and get recommended vaccinations to reduce the risk of infections that could increase your lymphoma risk. […] Therefore, effectively managing these infections may play a role in preventing lymphoma. […] Practising safe sexual behaviours, undergoing regular HIV testing, and adhering to treatment regimens if infected are essential steps in reducing the risk of both HIV and lymphoma.

• #47 CNS prophylaxis | Lymphoma Action

  https://lymphoma-action.org.uk/about-lymphoma-treatment-lymphoma-chemotherapy/cns-prophylaxis

  Most people have a low risk of their lymphoma spreading to the CNS and do not need CNS prophylaxis. […] If you are at high risk of your lymphoma spreading to your CNS, your medical team might offer you treatment that aims to stop it developing. This is called CNS prophylaxis. […] Your medical team will only suggest CNS prophylaxis if you have certain types of lymphoma, or risk factors that make your type of lymphoma more likely to spread to the CNS. […] CNS prophylaxis is part of the standard treatment for very fast-growing types of non-Hodgkin lymphoma, such as Burkitt lymphoma or lymphoblastic lymphoma. […] If you have DLBCL, your medical team is likely to recommend CNS prophylaxis if you have any of these factors: lymphoma in three or more places outside your lymph nodes, lymphoma in any of the following places: testicles, kidneys, adrenal glands, blood vessels, four or more of the following: high levels of a chemical called lactate dehydrogenase (LDH) in your blood, aged over 60, lymphoma that is stopping you working or being active, lymphoma in two or more places outside your lymph nodes, stage 3 or 4 lymphoma, lymphoma in your kidneys or your adrenal glands. […] Your medical team might also suggest CNS prophylaxis if you have DLBCL affecting your breasts or womb (uterus). […] Speak to your medical team if you are worried about your risk of developing lymphoma in your CNS. They can advise you on whether or not you need CNS prophylaxis.

• #48 Prevention and management of secondary central nervous system lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9973486/

  Secondary central nervous system (CNS) lymphoma (SCNSL) is defined by the involvement of the CNS, either at the time of initial diagnosis of systemic lymphoma or in the setting of relapse, and can be either isolated or with synchronous systemic disease. […] There has been growing interest in improving the definition of patients at increased risk of CNS relapse, as well as identifying effective prophylactic strategies to prevent it. […] In this review we discuss the clinical presentation, the identification of high-risk patients, prophylaxis strategies and recent treatment approaches for SCNSL as well as consider future directions. […] The CNS prognostic model (CNS-IPI), including the five standard International Prognostic Index factors (age 60 years, stage III/IV, 2 extranodal sites, elevated lactate dehydrogenase and performance status 2) and kidney or adrenal gland involvement, stratifies patients into three categories: low (0-2 risk factors), intermediate (2-3 risk factors) and high risk (4-6 risk factors) with 2-year rates of CNS relapse of 0.6%, 3.4% and 10.2%, respectively.

• #49 Prevention and management of secondary central nervous system lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9973486/

  Secondary central nervous system (CNS) lymphoma (SCNSL) is defined by the involvement of the CNS, either at the time of initial diagnosis of systemic lymphoma or in the setting of relapse, and can be either isolated or with synchronous systemic disease. […] There has been growing interest in improving the definition of patients at increased risk of CNS relapse, as well as identifying effective prophylactic strategies to prevent it. […] In this review we discuss the clinical presentation, the identification of high-risk patients, prophylaxis strategies and recent treatment approaches for SCNSL as well as consider future directions. […] The CNS prognostic model (CNS-IPI), including the five standard International Prognostic Index factors (age 60 years, stage III/IV, 2 extranodal sites, elevated lactate dehydrogenase and performance status 2) and kidney or adrenal gland involvement, stratifies patients into three categories: low (0-2 risk factors), intermediate (2-3 risk factors) and high risk (4-6 risk factors) with 2-year rates of CNS relapse of 0.6%, 3.4% and 10.2%, respectively.

• #50

  https://haematologica.org/article/view/7964

  Several studies and a recent meta-analysis have described a decrease in rates of CNS relapse in the post-rituximab era (probably due to improved control of systemic lymphoma), in addition to a change in the pattern of CNS relapse, with predominance of parenchymal over leptomeningeal relapse, isolated over combined (systemic plus CNS) relapses, and delayed CNS relapses. […] The identification of risk factors has been the major goal of many studies of CNS involvement. Several large retrospective studies conducted in the pre-rituximab era reported higher rates of CNS relapse in patients with increased serum lactate dehydrogenase (LDH) levels and/or involvement of 1 extranodal site, although these factors failed to predict CNS relapse in more than half of all cases. […] Based on all the above evidence, a new prognostic model to assess the risk of CNS disease in DLBCL (CNS-IPI) has been proposed. This model has been validated in other series from the British Columbia Cancer Agency, and includes the 5 IPI factors in addition to kidney/adrenal gland involvement, and it stratifies patients into 3 risk groups for CNS relapse: low risk (01 factors; 2-year risk of 0.6%), intermediate risk (23 factors; 2-year risk of 3.4%), and high risk (46 factors; 2-year risk of 10.2%).

• #51 Prevention and management of secondary central nervous system lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9973486/

  Secondary central nervous system (CNS) lymphoma (SCNSL) is defined by the involvement of the CNS, either at the time of initial diagnosis of systemic lymphoma or in the setting of relapse, and can be either isolated or with synchronous systemic disease. […] There has been growing interest in improving the definition of patients at increased risk of CNS relapse, as well as identifying effective prophylactic strategies to prevent it. […] In this review we discuss the clinical presentation, the identification of high-risk patients, prophylaxis strategies and recent treatment approaches for SCNSL as well as consider future directions. […] The CNS prognostic model (CNS-IPI), including the five standard International Prognostic Index factors (age 60 years, stage III/IV, 2 extranodal sites, elevated lactate dehydrogenase and performance status 2) and kidney or adrenal gland involvement, stratifies patients into three categories: low (0-2 risk factors), intermediate (2-3 risk factors) and high risk (4-6 risk factors) with 2-year rates of CNS relapse of 0.6%, 3.4% and 10.2%, respectively.

• #52 Prevention and management of secondary central nervous system lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9973486/

  Secondary central nervous system (CNS) lymphoma (SCNSL) is defined by the involvement of the CNS, either at the time of initial diagnosis of systemic lymphoma or in the setting of relapse, and can be either isolated or with synchronous systemic disease. […] There has been growing interest in improving the definition of patients at increased risk of CNS relapse, as well as identifying effective prophylactic strategies to prevent it. […] In this review we discuss the clinical presentation, the identification of high-risk patients, prophylaxis strategies and recent treatment approaches for SCNSL as well as consider future directions. […] The CNS prognostic model (CNS-IPI), including the five standard International Prognostic Index factors (age 60 years, stage III/IV, 2 extranodal sites, elevated lactate dehydrogenase and performance status 2) and kidney or adrenal gland involvement, stratifies patients into three categories: low (0-2 risk factors), intermediate (2-3 risk factors) and high risk (4-6 risk factors) with 2-year rates of CNS relapse of 0.6%, 3.4% and 10.2%, respectively.

• #53

  https://haematologica.org/article/view/7964

  Several studies and a recent meta-analysis have described a decrease in rates of CNS relapse in the post-rituximab era (probably due to improved control of systemic lymphoma), in addition to a change in the pattern of CNS relapse, with predominance of parenchymal over leptomeningeal relapse, isolated over combined (systemic plus CNS) relapses, and delayed CNS relapses. […] The identification of risk factors has been the major goal of many studies of CNS involvement. Several large retrospective studies conducted in the pre-rituximab era reported higher rates of CNS relapse in patients with increased serum lactate dehydrogenase (LDH) levels and/or involvement of 1 extranodal site, although these factors failed to predict CNS relapse in more than half of all cases. […] Based on all the above evidence, a new prognostic model to assess the risk of CNS disease in DLBCL (CNS-IPI) has been proposed. This model has been validated in other series from the British Columbia Cancer Agency, and includes the 5 IPI factors in addition to kidney/adrenal gland involvement, and it stratifies patients into 3 risk groups for CNS relapse: low risk (01 factors; 2-year risk of 0.6%), intermediate risk (23 factors; 2-year risk of 3.4%), and high risk (46 factors; 2-year risk of 10.2%).

• #54 CNS prophylaxis | Lymphoma Action

  https://lymphoma-action.org.uk/about-lymphoma-treatment-lymphoma-chemotherapy/cns-prophylaxis

  Most people have a low risk of their lymphoma spreading to the CNS and do not need CNS prophylaxis. […] If you are at high risk of your lymphoma spreading to your CNS, your medical team might offer you treatment that aims to stop it developing. This is called CNS prophylaxis. […] Your medical team will only suggest CNS prophylaxis if you have certain types of lymphoma, or risk factors that make your type of lymphoma more likely to spread to the CNS. […] CNS prophylaxis is part of the standard treatment for very fast-growing types of non-Hodgkin lymphoma, such as Burkitt lymphoma or lymphoblastic lymphoma. […] If you have DLBCL, your medical team is likely to recommend CNS prophylaxis if you have any of these factors: lymphoma in three or more places outside your lymph nodes, lymphoma in any of the following places: testicles, kidneys, adrenal glands, blood vessels, four or more of the following: high levels of a chemical called lactate dehydrogenase (LDH) in your blood, aged over 60, lymphoma that is stopping you working or being active, lymphoma in two or more places outside your lymph nodes, stage 3 or 4 lymphoma, lymphoma in your kidneys or your adrenal glands. […] Your medical team might also suggest CNS prophylaxis if you have DLBCL affecting your breasts or womb (uterus). […] Speak to your medical team if you are worried about your risk of developing lymphoma in your CNS. They can advise you on whether or not you need CNS prophylaxis.

• #55 CNS prophylaxis | Lymphoma Action

  https://lymphoma-action.org.uk/about-lymphoma-treatment-lymphoma-chemotherapy/cns-prophylaxis

  Most people have a low risk of their lymphoma spreading to the CNS and do not need CNS prophylaxis. […] If you are at high risk of your lymphoma spreading to your CNS, your medical team might offer you treatment that aims to stop it developing. This is called CNS prophylaxis. […] Your medical team will only suggest CNS prophylaxis if you have certain types of lymphoma, or risk factors that make your type of lymphoma more likely to spread to the CNS. […] CNS prophylaxis is part of the standard treatment for very fast-growing types of non-Hodgkin lymphoma, such as Burkitt lymphoma or lymphoblastic lymphoma. […] If you have DLBCL, your medical team is likely to recommend CNS prophylaxis if you have any of these factors: lymphoma in three or more places outside your lymph nodes, lymphoma in any of the following places: testicles, kidneys, adrenal glands, blood vessels, four or more of the following: high levels of a chemical called lactate dehydrogenase (LDH) in your blood, aged over 60, lymphoma that is stopping you working or being active, lymphoma in two or more places outside your lymph nodes, stage 3 or 4 lymphoma, lymphoma in your kidneys or your adrenal glands. […] Your medical team might also suggest CNS prophylaxis if you have DLBCL affecting your breasts or womb (uterus). […] Speak to your medical team if you are worried about your risk of developing lymphoma in your CNS. They can advise you on whether or not you need CNS prophylaxis.

• #56 CNS prophylaxis | Lymphoma Action

  https://lymphoma-action.org.uk/about-lymphoma-treatment-lymphoma-chemotherapy/cns-prophylaxis

  Most people have a low risk of their lymphoma spreading to the CNS and do not need CNS prophylaxis. […] If you are at high risk of your lymphoma spreading to your CNS, your medical team might offer you treatment that aims to stop it developing. This is called CNS prophylaxis. […] Your medical team will only suggest CNS prophylaxis if you have certain types of lymphoma, or risk factors that make your type of lymphoma more likely to spread to the CNS. […] CNS prophylaxis is part of the standard treatment for very fast-growing types of non-Hodgkin lymphoma, such as Burkitt lymphoma or lymphoblastic lymphoma. […] If you have DLBCL, your medical team is likely to recommend CNS prophylaxis if you have any of these factors: lymphoma in three or more places outside your lymph nodes, lymphoma in any of the following places: testicles, kidneys, adrenal glands, blood vessels, four or more of the following: high levels of a chemical called lactate dehydrogenase (LDH) in your blood, aged over 60, lymphoma that is stopping you working or being active, lymphoma in two or more places outside your lymph nodes, stage 3 or 4 lymphoma, lymphoma in your kidneys or your adrenal glands. […] Your medical team might also suggest CNS prophylaxis if you have DLBCL affecting your breasts or womb (uterus). […] Speak to your medical team if you are worried about your risk of developing lymphoma in your CNS. They can advise you on whether or not you need CNS prophylaxis.

• #57 Prophylaxis and Management of Secondary CNS Lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9529879/

  Because CNS relapse is associated with dismal outcomes, the standard approach to SCNSL emphasizes prevention. This requires identifying patients at high risk of CNS relapse and delivering CNS prophylaxis along with frontline therapy. […] The standard options are intrathecal (IT) chemotherapy and/or high-dose intravenous methotrexate (HD-MTX). […] However, neither method has been studied in a randomized prospective clinical trial and all evidence is hampered by a small number of events and variable selection criteria, treatment protocols, and participation in these protocols; indeed, many patients that are eligible for prophylaxis do not receive it. […] Despite these limitations, most available data do not show that either IT chemotherapy or HD-MTX substantially decreases the risk of CNS relapse.

• #58

  https://haematologica.org/article/view/7964

  The authors recommend screening patients for CNS involvement by lumbar puncture and cerebrospinal fluid (CSF) analysis by conventional cytology (CC) and FCM in order to provide prophylaxis in the following situations: Increased serum LDH and involvement of 1 extranodal site (recommendation 1, level of evidence B), Extranodal involvement of testis (recommendation 1, level of evidence B) or breast (recommendation 2, level of evidence B), Extranodal involvement of kidney, adrenal gland (recommendation 2, level of evidence C) or epidural space (recommendation 2, level of evidence D), High risk CNS-IPI (recommendation 2, level of evidence B), MYC rearrangements associated to BCL2 or BCL6 rearrangements (recommendation 2, level of evidence C). […] CNS-directed prophylaxis should be offered to patients at high-risk of CNS relapse (recommendation 1, level of evidence B). IV MTX is recommended as CNS prophylaxis in high-risk patients (recommendation 2, level of evidence B). IV MTX as CNS prophylaxis should be administered during primary therapy at a dose of 3 g/m2, alternating with immunochemotherapy (recommendation 1, level of evidence B), and should be given according to published treatment schemes and in the context of performance status and renal function. Delay of subsequent cycles of systemic immunochemotherapy should be avoided (recommendation 1, level of evidence B). […] Patients with primary testicular lymphoma should receive IT MTX during primary chemotherapy (recommendation 1, level of evidence B).

• #59 Prevention and management of secondary central nervous system lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9973486/

  Our approach to CNS prophylaxis is summarized in Figure 1. […] Prophylaxis with intrathecal (IT) methotrexate (MTX) and/or cytarabine, often combined with steroids, has been used historically in aggressive B-cell lymphomas. […] However, in the rituximab era, the majority of retrospective studies and post-hoc analyses from prospective trials showed lack of efficacy of IT prophylaxis. […] Recent retrospective series including older patients and high-risk DLBCL have shown similar results with no apparent benefit of IT prophylaxis. […] Over recent years, HD-MTX (3 g/m2) has been proposed as a potentially better prophylactic strategy in patients with high-risk DLBCL since the majority of relapses in the rituximab era occur in the brain parenchyma. […] Initial retrospective series suggested a potential benefit of HD-MTX in the prevention of CNS disease; however, in recent years, several large retrospective studies have failed to demonstrate a reduction in CNS relapse.

• #60 Prevention and management of secondary central nervous system lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9973486/

  Our approach to CNS prophylaxis is summarized in Figure 1. […] Prophylaxis with intrathecal (IT) methotrexate (MTX) and/or cytarabine, often combined with steroids, has been used historically in aggressive B-cell lymphomas. […] However, in the rituximab era, the majority of retrospective studies and post-hoc analyses from prospective trials showed lack of efficacy of IT prophylaxis. […] Recent retrospective series including older patients and high-risk DLBCL have shown similar results with no apparent benefit of IT prophylaxis. […] Over recent years, HD-MTX (3 g/m2) has been proposed as a potentially better prophylactic strategy in patients with high-risk DLBCL since the majority of relapses in the rituximab era occur in the brain parenchyma. […] Initial retrospective series suggested a potential benefit of HD-MTX in the prevention of CNS disease; however, in recent years, several large retrospective studies have failed to demonstrate a reduction in CNS relapse.

• #61

  https://haematologica.org/article/view/7964

  The authors recommend screening patients for CNS involvement by lumbar puncture and cerebrospinal fluid (CSF) analysis by conventional cytology (CC) and FCM in order to provide prophylaxis in the following situations: Increased serum LDH and involvement of 1 extranodal site (recommendation 1, level of evidence B), Extranodal involvement of testis (recommendation 1, level of evidence B) or breast (recommendation 2, level of evidence B), Extranodal involvement of kidney, adrenal gland (recommendation 2, level of evidence C) or epidural space (recommendation 2, level of evidence D), High risk CNS-IPI (recommendation 2, level of evidence B), MYC rearrangements associated to BCL2 or BCL6 rearrangements (recommendation 2, level of evidence C). […] CNS-directed prophylaxis should be offered to patients at high-risk of CNS relapse (recommendation 1, level of evidence B). IV MTX is recommended as CNS prophylaxis in high-risk patients (recommendation 2, level of evidence B). IV MTX as CNS prophylaxis should be administered during primary therapy at a dose of 3 g/m2, alternating with immunochemotherapy (recommendation 1, level of evidence B), and should be given according to published treatment schemes and in the context of performance status and renal function. Delay of subsequent cycles of systemic immunochemotherapy should be avoided (recommendation 1, level of evidence B). […] Patients with primary testicular lymphoma should receive IT MTX during primary chemotherapy (recommendation 1, level of evidence B).

• #62 Risk stratification and management algorithms for patients with diffuse large B-cell lymphoma and CNS involvement – Calimeri – Annals of Lymphoma

  https://aol.amegroups.org/article/view/5280/html

  Moreover, there is still no consensus on the most effective prophylaxis modality to prevent central nervous system dissemination as well as on the standard of care that can be used in patients with secondary central nervous system lymphoma. […] CNS prophylaxis should improve survival figures in patients with high-risk DLBCL. […] However, the optimal type of prophylaxis remains a matter of debate because this issue has been addressed in few single-arm prospective studies, and a single ongoing randomized trial exists (NCT02777736). […] In the last decades, whole-brain irradiation, the most commonly used prophylaxis strategy in highly-aggressive lymphomas was replaced by systemic and/or intrathecal chemotherapy, including methotrexate (MTX) and/or cytarabine (ARA-C) in particular. […] Despite the intrinsic limitations of collected data, our recommendation is to use 34 courses of MTX 3 g/m2 every two to three weeks at the end of R-CHOP treatment.

• #63

  https://haematologica.org/article/view/7964

  The authors recommend screening patients for CNS involvement by lumbar puncture and cerebrospinal fluid (CSF) analysis by conventional cytology (CC) and FCM in order to provide prophylaxis in the following situations: Increased serum LDH and involvement of 1 extranodal site (recommendation 1, level of evidence B), Extranodal involvement of testis (recommendation 1, level of evidence B) or breast (recommendation 2, level of evidence B), Extranodal involvement of kidney, adrenal gland (recommendation 2, level of evidence C) or epidural space (recommendation 2, level of evidence D), High risk CNS-IPI (recommendation 2, level of evidence B), MYC rearrangements associated to BCL2 or BCL6 rearrangements (recommendation 2, level of evidence C). […] CNS-directed prophylaxis should be offered to patients at high-risk of CNS relapse (recommendation 1, level of evidence B). IV MTX is recommended as CNS prophylaxis in high-risk patients (recommendation 2, level of evidence B). IV MTX as CNS prophylaxis should be administered during primary therapy at a dose of 3 g/m2, alternating with immunochemotherapy (recommendation 1, level of evidence B), and should be given according to published treatment schemes and in the context of performance status and renal function. Delay of subsequent cycles of systemic immunochemotherapy should be avoided (recommendation 1, level of evidence B). […] Patients with primary testicular lymphoma should receive IT MTX during primary chemotherapy (recommendation 1, level of evidence B).

• #64 Prophylaxis and Management of Secondary CNS Lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9529879/

  Because CNS relapse is associated with dismal outcomes, the standard approach to SCNSL emphasizes prevention. This requires identifying patients at high risk of CNS relapse and delivering CNS prophylaxis along with frontline therapy. […] The standard options are intrathecal (IT) chemotherapy and/or high-dose intravenous methotrexate (HD-MTX). […] However, neither method has been studied in a randomized prospective clinical trial and all evidence is hampered by a small number of events and variable selection criteria, treatment protocols, and participation in these protocols; indeed, many patients that are eligible for prophylaxis do not receive it. […] Despite these limitations, most available data do not show that either IT chemotherapy or HD-MTX substantially decreases the risk of CNS relapse.

• #65 Recent updates on central nervous system prophylaxis in patients with high-risk diffuse large B-cell lymphoma | Experimental Hematology & Oncology | Full Text

  https://ehoonline.biomedcentral.com/articles/10.1186/s40164-023-00467-2

  The use of central nervous system (CNS) prophylaxis for patients with diffuse large B-cell lymphoma (DLBCL) remains controversial. […] Accurate identification of patients at risk and the optimal approach to CNS prophylaxis therefore remains an area of unmet need. […] The existing literature, largely retrospective in nature, provides mixed conclusions regarding the efficacy of CNS prophylaxis. […] The utility of CNS prophylaxis has itself been challenged. […] Improved diagnostics for early detection of CNS relapses and newer therapeutics for CNS prophylaxis are areas of active investigation. […] Given that the benefits, risks and side effects of CNS prophylaxis have not been well established in existing literature, it is important that patients with the highest risk of developing CNS disease are appropriately selected to maximize benefits and minimize harm.

• #66 Prophylaxis and Management of Secondary CNS Lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9529879/

  Because CNS relapse is associated with dismal outcomes, the standard approach to SCNSL emphasizes prevention. This requires identifying patients at high risk of CNS relapse and delivering CNS prophylaxis along with frontline therapy. […] The standard options are intrathecal (IT) chemotherapy and/or high-dose intravenous methotrexate (HD-MTX). […] However, neither method has been studied in a randomized prospective clinical trial and all evidence is hampered by a small number of events and variable selection criteria, treatment protocols, and participation in these protocols; indeed, many patients that are eligible for prophylaxis do not receive it. […] Despite these limitations, most available data do not show that either IT chemotherapy or HD-MTX substantially decreases the risk of CNS relapse.

• #67 Prevention and management of secondary central nervous system lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9973486/

  Our approach to CNS prophylaxis is summarized in Figure 1. […] Prophylaxis with intrathecal (IT) methotrexate (MTX) and/or cytarabine, often combined with steroids, has been used historically in aggressive B-cell lymphomas. […] However, in the rituximab era, the majority of retrospective studies and post-hoc analyses from prospective trials showed lack of efficacy of IT prophylaxis. […] Recent retrospective series including older patients and high-risk DLBCL have shown similar results with no apparent benefit of IT prophylaxis. […] Over recent years, HD-MTX (3 g/m2) has been proposed as a potentially better prophylactic strategy in patients with high-risk DLBCL since the majority of relapses in the rituximab era occur in the brain parenchyma. […] Initial retrospective series suggested a potential benefit of HD-MTX in the prevention of CNS disease; however, in recent years, several large retrospective studies have failed to demonstrate a reduction in CNS relapse.

• #68

  https://haematologica.org/article/view/7964

  Several studies and a recent meta-analysis have described a decrease in rates of CNS relapse in the post-rituximab era (probably due to improved control of systemic lymphoma), in addition to a change in the pattern of CNS relapse, with predominance of parenchymal over leptomeningeal relapse, isolated over combined (systemic plus CNS) relapses, and delayed CNS relapses. […] The identification of risk factors has been the major goal of many studies of CNS involvement. Several large retrospective studies conducted in the pre-rituximab era reported higher rates of CNS relapse in patients with increased serum lactate dehydrogenase (LDH) levels and/or involvement of 1 extranodal site, although these factors failed to predict CNS relapse in more than half of all cases. […] Based on all the above evidence, a new prognostic model to assess the risk of CNS disease in DLBCL (CNS-IPI) has been proposed. This model has been validated in other series from the British Columbia Cancer Agency, and includes the 5 IPI factors in addition to kidney/adrenal gland involvement, and it stratifies patients into 3 risk groups for CNS relapse: low risk (01 factors; 2-year risk of 0.6%), intermediate risk (23 factors; 2-year risk of 3.4%), and high risk (46 factors; 2-year risk of 10.2%).

• #69 Risk stratification and management algorithms for patients with diffuse large B-cell lymphoma and CNS involvement – Calimeri – Annals of Lymphoma

  https://aol.amegroups.org/article/view/5280/html

  HD-MTX is contraindicated in patients with renal failure or effusions/generalized edema because this drug cumulates in third space and is slowly released, resulting in prolonged exposure and enhanced toxicity. […] Thus, despite the optimal treatment approach for such patients is still not known, policy in our Institution is to manage them as SCNSL.

• #70 Recent updates on central nervous system prophylaxis in patients with high-risk diffuse large B-cell lymphoma | Experimental Hematology & Oncology | Full Text

  https://ehoonline.biomedcentral.com/articles/10.1186/s40164-023-00467-2

  Practices differ globally regarding the use of CNS prophylaxis in patients with DLBCL. […] While intravenous high-dose methotrexate (IV HD-MTX) appears to be a preferred option across various guidelines, it utilizes more resources given the need for inpatient monitoring, hydration, alkalinization of urine and drug clearance. […] In settings where resources are limited or if patients are not fit for IV HD-MTX, intrathecal methotrexate (IT MTX) remains an alternative option. […] Importantly, high risk anatomical sites such as breast and testis involvement as well as consideration of cell of origin have a significant impact in prognosticating for CNS relapses. […] The concept of CNS tropism that may be identified via biological markers is an ongoing area of research. […] Therefore, risk assessment of CNS relapse for DLBCL patients should perhaps utilize the combination of CNS-IPI score and COO.

• #71 Prophylaxis and Management of Secondary CNS Lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9529879/

  Nevertheless, given the poor prognosis of patients with CNS relapse and the limitations of the data, we continue to use IT chemotherapy prophylaxis for our patients with high-risk of CNS spread including those with 2 sites of extranodal involvement and concomitantly elevated LDH, MYC rearrangement, bone marrow involvement by large cell lymphoma, and HIV positivity.

• #72 Antimicrobial Prophylaxis in Lymphoma by Chemotherapy Regimen

  https://www.scientificarchives.com/article/antimicrobial-prophylaxis-in-lymphoma-by-chemotherapy-regimen

  Antimicrobial Prophylaxis in Lymphoma by Chemotherapy Regimen […] Treatment of lymphomas involves a wide variety of chemotherapy, immunotherapy, and targeted-agents tailored to disease biology and patient characteristics. Each of these regimens carry their own risk of opportunistic infections in an immunocompromised population. […] Clinical trials, patient co-morbidities, and institutional preferences all play a role in determining the preferred antimicrobial prophylaxis. While there is a paucity of data on systematic reviews and guidelines for standardized chemotherapy regimens in lymphoma patients, the efficacy and recommendations for antimicrobial prophylaxis in specific chemotherapy regimens for lymphoma has not been fully reviewed. […] This review article analyzes numerous research studies with summarization of findings and antimicrobial prophylaxis recommendations based on specific lymphoma chemotherapy regimens. With regards to each specific chemotherapy regimen assessed, indications for antibacterial, anti-viral, anti-fungal, and Pneumocystis jiroveci pneumonia (PJP) prophylaxis were determined for each regimen. The degree of immunosuppression and the necessary prophylaxis varies across different regimens and lymphoma subgroups; and thus, an individualized approach is necessary to optimize the supportive care during lymphoma treatment.

• #73 Lymphoma and Infection: Do I Need to Take Medication to Prevent Infection? – New Developments in Lymphoma

  https://cornell-lymphoma.com/2013/04/30/lymphoma-and-infection-do-i-need-to-take-medication-to-prevent-infection/

  In some instances, patients may be started on medicines to prevent or minimize infection. […] Prophylaxis is recommended for intermediate or high-risk patients, including patients that are expected to have neutropenia. […] The use of levofloxacin prophylaxis is only recommended for patients with neutropenia that lasts longer than 7 days. […] ASCO guidelines recommend considering prophylaxis only for patients with profoundly low white blood cell counts (ANC 100) longer than 7 days. […] Antiviral medications may be recommended. […] You may require preventative medication, typically with TMP-SMX, if you are on steroids for a prolonged period of time (1 month), or are receiving treatment with alemtuzumab or purine analogs (i.e., fludarabine). […] ASCO 2012 guidelines recommended all patients who are receiving cancer treatment to receive the seasonal flu vaccine, along with their family and household contacts. […] Guidelines from the Centers for Disease Control (CDC) include administration of a pneumococcal vaccine in all patients with lymphoma.

• #74 Antimicrobial Prophylaxis in Lymphoma by Chemotherapy Regimen

  https://www.scientificarchives.com/article/antimicrobial-prophylaxis-in-lymphoma-by-chemotherapy-regimen

  Antimicrobial Prophylaxis in Lymphoma by Chemotherapy Regimen […] Treatment of lymphomas involves a wide variety of chemotherapy, immunotherapy, and targeted-agents tailored to disease biology and patient characteristics. Each of these regimens carry their own risk of opportunistic infections in an immunocompromised population. […] Clinical trials, patient co-morbidities, and institutional preferences all play a role in determining the preferred antimicrobial prophylaxis. While there is a paucity of data on systematic reviews and guidelines for standardized chemotherapy regimens in lymphoma patients, the efficacy and recommendations for antimicrobial prophylaxis in specific chemotherapy regimens for lymphoma has not been fully reviewed. […] This review article analyzes numerous research studies with summarization of findings and antimicrobial prophylaxis recommendations based on specific lymphoma chemotherapy regimens. With regards to each specific chemotherapy regimen assessed, indications for antibacterial, anti-viral, anti-fungal, and Pneumocystis jiroveci pneumonia (PJP) prophylaxis were determined for each regimen. The degree of immunosuppression and the necessary prophylaxis varies across different regimens and lymphoma subgroups; and thus, an individualized approach is necessary to optimize the supportive care during lymphoma treatment.

• #75 Lymphoma and Infection: Do I Need to Take Medication to Prevent Infection? – New Developments in Lymphoma

  https://cornell-lymphoma.com/2013/04/30/lymphoma-and-infection-do-i-need-to-take-medication-to-prevent-infection/

  In some instances, patients may be started on medicines to prevent or minimize infection. […] Prophylaxis is recommended for intermediate or high-risk patients, including patients that are expected to have neutropenia. […] The use of levofloxacin prophylaxis is only recommended for patients with neutropenia that lasts longer than 7 days. […] ASCO guidelines recommend considering prophylaxis only for patients with profoundly low white blood cell counts (ANC 100) longer than 7 days. […] Antiviral medications may be recommended. […] You may require preventative medication, typically with TMP-SMX, if you are on steroids for a prolonged period of time (1 month), or are receiving treatment with alemtuzumab or purine analogs (i.e., fludarabine). […] ASCO 2012 guidelines recommended all patients who are receiving cancer treatment to receive the seasonal flu vaccine, along with their family and household contacts. […] Guidelines from the Centers for Disease Control (CDC) include administration of a pneumococcal vaccine in all patients with lymphoma.

• #76 Lymphoma and Infection: Do I Need to Take Medication to Prevent Infection? – New Developments in Lymphoma

  https://cornell-lymphoma.com/2013/04/30/lymphoma-and-infection-do-i-need-to-take-medication-to-prevent-infection/

  In some instances, patients may be started on medicines to prevent or minimize infection. […] Prophylaxis is recommended for intermediate or high-risk patients, including patients that are expected to have neutropenia. […] The use of levofloxacin prophylaxis is only recommended for patients with neutropenia that lasts longer than 7 days. […] ASCO guidelines recommend considering prophylaxis only for patients with profoundly low white blood cell counts (ANC 100) longer than 7 days. […] Antiviral medications may be recommended. […] You may require preventative medication, typically with TMP-SMX, if you are on steroids for a prolonged period of time (1 month), or are receiving treatment with alemtuzumab or purine analogs (i.e., fludarabine). […] ASCO 2012 guidelines recommended all patients who are receiving cancer treatment to receive the seasonal flu vaccine, along with their family and household contacts. […] Guidelines from the Centers for Disease Control (CDC) include administration of a pneumococcal vaccine in all patients with lymphoma.

• #77 Lymphoma and Infection: Do I Need to Take Medication to Prevent Infection? – New Developments in Lymphoma

  https://cornell-lymphoma.com/2013/04/30/lymphoma-and-infection-do-i-need-to-take-medication-to-prevent-infection/

  In some instances, patients may be started on medicines to prevent or minimize infection. […] Prophylaxis is recommended for intermediate or high-risk patients, including patients that are expected to have neutropenia. […] The use of levofloxacin prophylaxis is only recommended for patients with neutropenia that lasts longer than 7 days. […] ASCO guidelines recommend considering prophylaxis only for patients with profoundly low white blood cell counts (ANC 100) longer than 7 days. […] Antiviral medications may be recommended. […] You may require preventative medication, typically with TMP-SMX, if you are on steroids for a prolonged period of time (1 month), or are receiving treatment with alemtuzumab or purine analogs (i.e., fludarabine). […] ASCO 2012 guidelines recommended all patients who are receiving cancer treatment to receive the seasonal flu vaccine, along with their family and household contacts. […] Guidelines from the Centers for Disease Control (CDC) include administration of a pneumococcal vaccine in all patients with lymphoma.

• #78 Lymphoma and Infection: Do I Need to Take Medication to Prevent Infection? – New Developments in Lymphoma

  https://cornell-lymphoma.com/2013/04/30/lymphoma-and-infection-do-i-need-to-take-medication-to-prevent-infection/

  In some instances, patients may be started on medicines to prevent or minimize infection. […] Prophylaxis is recommended for intermediate or high-risk patients, including patients that are expected to have neutropenia. […] The use of levofloxacin prophylaxis is only recommended for patients with neutropenia that lasts longer than 7 days. […] ASCO guidelines recommend considering prophylaxis only for patients with profoundly low white blood cell counts (ANC 100) longer than 7 days. […] Antiviral medications may be recommended. […] You may require preventative medication, typically with TMP-SMX, if you are on steroids for a prolonged period of time (1 month), or are receiving treatment with alemtuzumab or purine analogs (i.e., fludarabine). […] ASCO 2012 guidelines recommended all patients who are receiving cancer treatment to receive the seasonal flu vaccine, along with their family and household contacts. […] Guidelines from the Centers for Disease Control (CDC) include administration of a pneumococcal vaccine in all patients with lymphoma.

• #79 Lymphoma and Infection: Do I Need to Take Medication to Prevent Infection? – New Developments in Lymphoma

  https://cornell-lymphoma.com/2013/04/30/lymphoma-and-infection-do-i-need-to-take-medication-to-prevent-infection/

  In some instances, patients may be started on medicines to prevent or minimize infection. […] Prophylaxis is recommended for intermediate or high-risk patients, including patients that are expected to have neutropenia. […] The use of levofloxacin prophylaxis is only recommended for patients with neutropenia that lasts longer than 7 days. […] ASCO guidelines recommend considering prophylaxis only for patients with profoundly low white blood cell counts (ANC 100) longer than 7 days. […] Antiviral medications may be recommended. […] You may require preventative medication, typically with TMP-SMX, if you are on steroids for a prolonged period of time (1 month), or are receiving treatment with alemtuzumab or purine analogs (i.e., fludarabine). […] ASCO 2012 guidelines recommended all patients who are receiving cancer treatment to receive the seasonal flu vaccine, along with their family and household contacts. […] Guidelines from the Centers for Disease Control (CDC) include administration of a pneumococcal vaccine in all patients with lymphoma.

• #80 Antimicrobial Prophylaxis in Lymphoma by Chemotherapy Regimen

  https://www.scientificarchives.com/article/antimicrobial-prophylaxis-in-lymphoma-by-chemotherapy-regimen

  General prophylaxis indications and duration of antimicrobial therapy can be referenced in Table 3. Assuming no definite contraindications, the preferred first-line antimicrobial prophylactic agents are: levofloxacin 500 mg or 750 mg daily for anti-bacterial prophylaxis, acyclovir 400 mg twice daily for anti-viral prophylaxis, fluconazole 400 mg daily for anti-fungal prophylaxis, and trimethoprim-sulfamethoxazole (TMP-SMX) 1 double strength (800 mg/160 mg) tablet three times weekly for PJP prophylaxis. […] Given the complexity in determining the appropriate antimicrobial prophylaxis in lymphoma based on the specific chemotherapy regimen, classifying prophylaxis indications based on treatment regimens will assist in guiding clinicians when treating lymphoma. Conversely, understanding indications for prophylaxis is imperative to preventing unnecessary prescribing of antimicrobial prophylaxis. This knowledge will limit medication adverse effects, prevent antibiotic resistance, and reduce avoidable costs.

• #81 Antimicrobial Prophylaxis in Lymphoma by Chemotherapy Regimen

  https://www.scientificarchives.com/article/antimicrobial-prophylaxis-in-lymphoma-by-chemotherapy-regimen

  General prophylaxis indications and duration of antimicrobial therapy can be referenced in Table 3. Assuming no definite contraindications, the preferred first-line antimicrobial prophylactic agents are: levofloxacin 500 mg or 750 mg daily for anti-bacterial prophylaxis, acyclovir 400 mg twice daily for anti-viral prophylaxis, fluconazole 400 mg daily for anti-fungal prophylaxis, and trimethoprim-sulfamethoxazole (TMP-SMX) 1 double strength (800 mg/160 mg) tablet three times weekly for PJP prophylaxis. […] Given the complexity in determining the appropriate antimicrobial prophylaxis in lymphoma based on the specific chemotherapy regimen, classifying prophylaxis indications based on treatment regimens will assist in guiding clinicians when treating lymphoma. Conversely, understanding indications for prophylaxis is imperative to preventing unnecessary prescribing of antimicrobial prophylaxis. This knowledge will limit medication adverse effects, prevent antibiotic resistance, and reduce avoidable costs.

• #82 Antimicrobial Prophylaxis in Lymphoma by Chemotherapy Regimen

  https://www.scientificarchives.com/article/antimicrobial-prophylaxis-in-lymphoma-by-chemotherapy-regimen

  General prophylaxis indications and duration of antimicrobial therapy can be referenced in Table 3. Assuming no definite contraindications, the preferred first-line antimicrobial prophylactic agents are: levofloxacin 500 mg or 750 mg daily for anti-bacterial prophylaxis, acyclovir 400 mg twice daily for anti-viral prophylaxis, fluconazole 400 mg daily for anti-fungal prophylaxis, and trimethoprim-sulfamethoxazole (TMP-SMX) 1 double strength (800 mg/160 mg) tablet three times weekly for PJP prophylaxis. […] Given the complexity in determining the appropriate antimicrobial prophylaxis in lymphoma based on the specific chemotherapy regimen, classifying prophylaxis indications based on treatment regimens will assist in guiding clinicians when treating lymphoma. Conversely, understanding indications for prophylaxis is imperative to preventing unnecessary prescribing of antimicrobial prophylaxis. This knowledge will limit medication adverse effects, prevent antibiotic resistance, and reduce avoidable costs.

• #83 Antimicrobial Prophylaxis in Lymphoma by Chemotherapy Regimen

  https://www.scientificarchives.com/article/antimicrobial-prophylaxis-in-lymphoma-by-chemotherapy-regimen

  General prophylaxis indications and duration of antimicrobial therapy can be referenced in Table 3. Assuming no definite contraindications, the preferred first-line antimicrobial prophylactic agents are: levofloxacin 500 mg or 750 mg daily for anti-bacterial prophylaxis, acyclovir 400 mg twice daily for anti-viral prophylaxis, fluconazole 400 mg daily for anti-fungal prophylaxis, and trimethoprim-sulfamethoxazole (TMP-SMX) 1 double strength (800 mg/160 mg) tablet three times weekly for PJP prophylaxis. […] Given the complexity in determining the appropriate antimicrobial prophylaxis in lymphoma based on the specific chemotherapy regimen, classifying prophylaxis indications based on treatment regimens will assist in guiding clinicians when treating lymphoma. Conversely, understanding indications for prophylaxis is imperative to preventing unnecessary prescribing of antimicrobial prophylaxis. This knowledge will limit medication adverse effects, prevent antibiotic resistance, and reduce avoidable costs.

• #84 Antimicrobial Prophylaxis in Lymphoma by Chemotherapy Regimen

  https://www.scientificarchives.com/article/antimicrobial-prophylaxis-in-lymphoma-by-chemotherapy-regimen

  General prophylaxis indications and duration of antimicrobial therapy can be referenced in Table 3. Assuming no definite contraindications, the preferred first-line antimicrobial prophylactic agents are: levofloxacin 500 mg or 750 mg daily for anti-bacterial prophylaxis, acyclovir 400 mg twice daily for anti-viral prophylaxis, fluconazole 400 mg daily for anti-fungal prophylaxis, and trimethoprim-sulfamethoxazole (TMP-SMX) 1 double strength (800 mg/160 mg) tablet three times weekly for PJP prophylaxis. […] Given the complexity in determining the appropriate antimicrobial prophylaxis in lymphoma based on the specific chemotherapy regimen, classifying prophylaxis indications based on treatment regimens will assist in guiding clinicians when treating lymphoma. Conversely, understanding indications for prophylaxis is imperative to preventing unnecessary prescribing of antimicrobial prophylaxis. This knowledge will limit medication adverse effects, prevent antibiotic resistance, and reduce avoidable costs.

• #85 Lymphoma and Infection: Do I Need to Take Medication to Prevent Infection? – New Developments in Lymphoma

  https://cornell-lymphoma.com/2013/04/30/lymphoma-and-infection-do-i-need-to-take-medication-to-prevent-infection/

  In some instances, patients may be started on medicines to prevent or minimize infection. […] Prophylaxis is recommended for intermediate or high-risk patients, including patients that are expected to have neutropenia. […] The use of levofloxacin prophylaxis is only recommended for patients with neutropenia that lasts longer than 7 days. […] ASCO guidelines recommend considering prophylaxis only for patients with profoundly low white blood cell counts (ANC 100) longer than 7 days. […] Antiviral medications may be recommended. […] You may require preventative medication, typically with TMP-SMX, if you are on steroids for a prolonged period of time (1 month), or are receiving treatment with alemtuzumab or purine analogs (i.e., fludarabine). […] ASCO 2012 guidelines recommended all patients who are receiving cancer treatment to receive the seasonal flu vaccine, along with their family and household contacts. […] Guidelines from the Centers for Disease Control (CDC) include administration of a pneumococcal vaccine in all patients with lymphoma.

• #86 Same-Day Pegfilgrastim or Pegfilgrastim-cbqv Prophylaxis in miniCHOP Chemotherapy-Based Regimens for Non-Hodgkin Lymphoma

  https://jhoponline.com/special-issues/2021-year-in-review-biosimilars/19175:same-day-pegfilgrastim-or-pegfilgrastim-cbqv-prophylaxis-in-minichop-chemotherapy-based-regimens-for-non-hodgkin-lymphoma

  The results of a retrospective, single-center analysis demonstrated that same-day pegfilgrastim or pegfilgrastim-cbqv was safe and effective in patients with diffuse large B-cell lymphoma who received a rituximab plus miniCHOP chemotherapy regimen, with no significant increase in febrile neutropenia or delayed engraftment. […] All patients treated with the miniCHOP regimen received pegfilgrastim or its biosimilar pegfilgrastim-cbqv on the same day for febrile neutropenia (FN) prophylaxis. […] Based on these results, the authors concluded that same-day pegfilgrastim or pegfilgrastim-cbqv was safe and effective in patients with DLBCL who received the miniR-CHOP chemotherapy regimen, with no significant increase in FN or delayed engraftment.

• #87 Lymphoma and Infection: Do I Need to Take Medication to Prevent Infection? – New Developments in Lymphoma

  https://cornell-lymphoma.com/2013/04/30/lymphoma-and-infection-do-i-need-to-take-medication-to-prevent-infection/

  In some instances, patients may be started on medicines to prevent or minimize infection. […] Prophylaxis is recommended for intermediate or high-risk patients, including patients that are expected to have neutropenia. […] The use of levofloxacin prophylaxis is only recommended for patients with neutropenia that lasts longer than 7 days. […] ASCO guidelines recommend considering prophylaxis only for patients with profoundly low white blood cell counts (ANC 100) longer than 7 days. […] Antiviral medications may be recommended. […] You may require preventative medication, typically with TMP-SMX, if you are on steroids for a prolonged period of time (1 month), or are receiving treatment with alemtuzumab or purine analogs (i.e., fludarabine). […] ASCO 2012 guidelines recommended all patients who are receiving cancer treatment to receive the seasonal flu vaccine, along with their family and household contacts. […] Guidelines from the Centers for Disease Control (CDC) include administration of a pneumococcal vaccine in all patients with lymphoma.

• #88 Lymphoma and Infection: Do I Need to Take Medication to Prevent Infection? – New Developments in Lymphoma

  https://cornell-lymphoma.com/2013/04/30/lymphoma-and-infection-do-i-need-to-take-medication-to-prevent-infection/

  In some instances, patients may be started on medicines to prevent or minimize infection. […] Prophylaxis is recommended for intermediate or high-risk patients, including patients that are expected to have neutropenia. […] The use of levofloxacin prophylaxis is only recommended for patients with neutropenia that lasts longer than 7 days. […] ASCO guidelines recommend considering prophylaxis only for patients with profoundly low white blood cell counts (ANC 100) longer than 7 days. […] Antiviral medications may be recommended. […] You may require preventative medication, typically with TMP-SMX, if you are on steroids for a prolonged period of time (1 month), or are receiving treatment with alemtuzumab or purine analogs (i.e., fludarabine). […] ASCO 2012 guidelines recommended all patients who are receiving cancer treatment to receive the seasonal flu vaccine, along with their family and household contacts. […] Guidelines from the Centers for Disease Control (CDC) include administration of a pneumococcal vaccine in all patients with lymphoma.

• #89 Lymphoma and Infection: Do I Need to Take Medication to Prevent Infection? – New Developments in Lymphoma

  https://cornell-lymphoma.com/2013/04/30/lymphoma-and-infection-do-i-need-to-take-medication-to-prevent-infection/

  In some instances, patients may be started on medicines to prevent or minimize infection. […] Prophylaxis is recommended for intermediate or high-risk patients, including patients that are expected to have neutropenia. […] The use of levofloxacin prophylaxis is only recommended for patients with neutropenia that lasts longer than 7 days. […] ASCO guidelines recommend considering prophylaxis only for patients with profoundly low white blood cell counts (ANC 100) longer than 7 days. […] Antiviral medications may be recommended. […] You may require preventative medication, typically with TMP-SMX, if you are on steroids for a prolonged period of time (1 month), or are receiving treatment with alemtuzumab or purine analogs (i.e., fludarabine). […] ASCO 2012 guidelines recommended all patients who are receiving cancer treatment to receive the seasonal flu vaccine, along with their family and household contacts. […] Guidelines from the Centers for Disease Control (CDC) include administration of a pneumococcal vaccine in all patients with lymphoma.

• #90 Hodgkin Lymphoma: Symptoms, Causes, Risk Factors and Prevention – Pi Health Cancer Hospital

  https://www.pihealthcancerhospital.com/blog/hodgkin-lymphoma-symptoms-causes-risk-factors-and-prevention/

  Balanced Diet: A diet high in fruits, vegetables, and whole grains helps improve overall immunological health. […] Regular Exercise: Regular physical activity promotes good weight management and immunological function. […] Avoiding Tobacco and Limiting Alcohol: To minimize your risk of cancer, including Hodgkin lymphoma, stop smoking and limit your alcohol use. […] Regular medical check-ups: […] Health Monitoring: Regular check-ups might uncover uncommon symptoms early on. […] Vaccines: Keeping up with vaccines, including those that protect against viral illnesses such as HPV and hepatitis B, can help safeguard your immune system.

• #91 Burkitt Lymphoma and Burkitt-like Lymphoma Treatment & Management: Approach Considerations, Chemotherapy Overview, CODOX-M/IVAC Regimen (Magrath Regimen)

  https://emedicine.medscape.com/article/1447602-treatment

  It is critical to closely monitor serum chemistries in patients with Burkitt lymphoma (BL), especially during chemotherapy because of the high risk of tumor lysis syndrome and uric acid nephropathy. Prophylactic allopurinol and aggressive hydration with urine alkalinization should be administered. […] Most patients with Burkitt lymphoma are considered at high risk for tumor lysis and meet the criteria for upfront treatment with rasburicase, which should be administered at a dose of 0.20 mg/kg IV daily for 5 days. […] Kidney failure as a result of tumor lysis syndrome from therapy is a potential risk in all patients, especially those with a high tumor burden. Aggressive management of this potentially life-threatening complication should be clearly addressed. Early hemodialysis should be considered in these patients to prevent long-term renal dysfunction.

• #92 Burkitt Lymphoma and Burkitt-like Lymphoma Treatment & Management: Approach Considerations, Chemotherapy Overview, CODOX-M/IVAC Regimen (Magrath Regimen)

  https://emedicine.medscape.com/article/1447602-treatment

  It is critical to closely monitor serum chemistries in patients with Burkitt lymphoma (BL), especially during chemotherapy because of the high risk of tumor lysis syndrome and uric acid nephropathy. Prophylactic allopurinol and aggressive hydration with urine alkalinization should be administered. […] Most patients with Burkitt lymphoma are considered at high risk for tumor lysis and meet the criteria for upfront treatment with rasburicase, which should be administered at a dose of 0.20 mg/kg IV daily for 5 days. […] Kidney failure as a result of tumor lysis syndrome from therapy is a potential risk in all patients, especially those with a high tumor burden. Aggressive management of this potentially life-threatening complication should be clearly addressed. Early hemodialysis should be considered in these patients to prevent long-term renal dysfunction.

• #93 Burkitt Lymphoma and Burkitt-like Lymphoma Treatment & Management: Approach Considerations, Chemotherapy Overview, CODOX-M/IVAC Regimen (Magrath Regimen)

  https://emedicine.medscape.com/article/1447602-treatment

  It is critical to closely monitor serum chemistries in patients with Burkitt lymphoma (BL), especially during chemotherapy because of the high risk of tumor lysis syndrome and uric acid nephropathy. Prophylactic allopurinol and aggressive hydration with urine alkalinization should be administered. […] Most patients with Burkitt lymphoma are considered at high risk for tumor lysis and meet the criteria for upfront treatment with rasburicase, which should be administered at a dose of 0.20 mg/kg IV daily for 5 days. […] Kidney failure as a result of tumor lysis syndrome from therapy is a potential risk in all patients, especially those with a high tumor burden. Aggressive management of this potentially life-threatening complication should be clearly addressed. Early hemodialysis should be considered in these patients to prevent long-term renal dysfunction.

• #94 Burkitt Lymphoma and Burkitt-like Lymphoma Treatment & Management: Approach Considerations, Chemotherapy Overview, CODOX-M/IVAC Regimen (Magrath Regimen)

  https://emedicine.medscape.com/article/1447602-treatment

  It is critical to closely monitor serum chemistries in patients with Burkitt lymphoma (BL), especially during chemotherapy because of the high risk of tumor lysis syndrome and uric acid nephropathy. Prophylactic allopurinol and aggressive hydration with urine alkalinization should be administered. […] Most patients with Burkitt lymphoma are considered at high risk for tumor lysis and meet the criteria for upfront treatment with rasburicase, which should be administered at a dose of 0.20 mg/kg IV daily for 5 days. […] Kidney failure as a result of tumor lysis syndrome from therapy is a potential risk in all patients, especially those with a high tumor burden. Aggressive management of this potentially life-threatening complication should be clearly addressed. Early hemodialysis should be considered in these patients to prevent long-term renal dysfunction.

• #95 Burkitt Lymphoma and Burkitt-like Lymphoma Treatment & Management: Approach Considerations, Chemotherapy Overview, CODOX-M/IVAC Regimen (Magrath Regimen)

  https://emedicine.medscape.com/article/1447602-treatment

  It is critical to closely monitor serum chemistries in patients with Burkitt lymphoma (BL), especially during chemotherapy because of the high risk of tumor lysis syndrome and uric acid nephropathy. Prophylactic allopurinol and aggressive hydration with urine alkalinization should be administered. […] Most patients with Burkitt lymphoma are considered at high risk for tumor lysis and meet the criteria for upfront treatment with rasburicase, which should be administered at a dose of 0.20 mg/kg IV daily for 5 days. […] Kidney failure as a result of tumor lysis syndrome from therapy is a potential risk in all patients, especially those with a high tumor burden. Aggressive management of this potentially life-threatening complication should be clearly addressed. Early hemodialysis should be considered in these patients to prevent long-term renal dysfunction.

• #96 Reducing your risk for non-Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/non-hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing non-Hodgkin lymphoma (NHL) by doing the following. […] Avoid or lower your long-term exposure to pesticides. […] You may lower your risk by having a healthy body weight. […] Follow occupational and safety guidelines when working with hazardous chemicals. […] Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for NHL.

• #97 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  As excessive alcohol consumption can weaken an individual’s immune system, it is recommended to limit its consumption to reduce the risk of lymphoma. […] Certain infections associated with lymphoma, such as Epstein-Barr virus or Hepatitis C virus (HCV), can hamper the healthy DNA of the cells; treating them can help in potential lymphoma prevention as well. […] Minimizing excessive exposure to toxic chemicals, such as benzene, can also help reduce the risk of developing lymphoma. […] As radiation exposure can damage the DNA structure of healthy cells, leading to an increased risk of lymphoma, it is often recommended to limit radiation exposure as much as possible. […] As lymphoma affects the lymphatic system, an important part of the immune system, experts advise making efforts to maintain a healthy immune system for potential lymphoma prevention.

• #98 Reducing your risk for non-Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/non-hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing non-Hodgkin lymphoma (NHL) by doing the following. […] Avoid or lower your long-term exposure to pesticides. […] You may lower your risk by having a healthy body weight. […] Follow occupational and safety guidelines when working with hazardous chemicals. […] Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for NHL.

• #99 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  As excessive alcohol consumption can weaken an individual’s immune system, it is recommended to limit its consumption to reduce the risk of lymphoma. […] Certain infections associated with lymphoma, such as Epstein-Barr virus or Hepatitis C virus (HCV), can hamper the healthy DNA of the cells; treating them can help in potential lymphoma prevention as well. […] Minimizing excessive exposure to toxic chemicals, such as benzene, can also help reduce the risk of developing lymphoma. […] As radiation exposure can damage the DNA structure of healthy cells, leading to an increased risk of lymphoma, it is often recommended to limit radiation exposure as much as possible. […] As lymphoma affects the lymphatic system, an important part of the immune system, experts advise making efforts to maintain a healthy immune system for potential lymphoma prevention.

• #100 Reducing your risk for non-Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/non-hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing non-Hodgkin lymphoma (NHL) by doing the following. […] Avoid or lower your long-term exposure to pesticides. […] You may lower your risk by having a healthy body weight. […] Follow occupational and safety guidelines when working with hazardous chemicals. […] Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for NHL.

• #101 Reducing your risk for non-Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/non-hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing non-Hodgkin lymphoma (NHL) by doing the following. […] Avoid or lower your long-term exposure to pesticides. […] You may lower your risk by having a healthy body weight. […] Follow occupational and safety guidelines when working with hazardous chemicals. […] Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for NHL.

• #102 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  As excessive alcohol consumption can weaken an individual’s immune system, it is recommended to limit its consumption to reduce the risk of lymphoma. […] Certain infections associated with lymphoma, such as Epstein-Barr virus or Hepatitis C virus (HCV), can hamper the healthy DNA of the cells; treating them can help in potential lymphoma prevention as well. […] Minimizing excessive exposure to toxic chemicals, such as benzene, can also help reduce the risk of developing lymphoma. […] As radiation exposure can damage the DNA structure of healthy cells, leading to an increased risk of lymphoma, it is often recommended to limit radiation exposure as much as possible. […] As lymphoma affects the lymphatic system, an important part of the immune system, experts advise making efforts to maintain a healthy immune system for potential lymphoma prevention.

• #103

  https://www.americanoncology.com/cancer-we-treat/prevention/lymphoma-cancer

  The risk of lymphoma can be reduced by: […] Avoiding activities that increase the chance of getting infected with AIDS and hepatitis C […] Avoiding unnecessary exposure to harmful chemicals and radiation, as overexposure to industrial and agricultural chemicals enhances the risk of lymphoma […] Getting regularly screened after the age of 50 […] Quitting smoking […] Following a healthy eating pattern […] Being physically active.

• #104 Non Hodgkin’s Lymphoma Prevention Strategies – Acibadem Health Point – ACIBADEM Hospitals – Acibadem Health Group

  https://www.acibademhealthpoint.com/non-hodgkins-lymphoma-prevention-strategies/

  Studies in the Journal of Occupational and Environmental Medicine point to pesticides as a lymphoma risk. They show a clear link. Being careful, like wearing protective clothes and picking organic, lowers this risk. […] It’s key to find lymphoma early for better prevention. Having check-ups often and checking genes are big helps. They spot risks early and make doing something about it easier. […] Seeing the doctor often is great for stopping lymphoma. Doctors can find signs early, helping you get care quickly. Keeping up with check-ups helps catch any problems fast. […] If lymphoma runs in your family, genetic testing is important. It looks for signs in your genes that mean a higher risk. Combining this with regular check-ups boosts finding problems early. […] Eating right is key to staying healthy and avoiding illnesses like lymphoma. Health experts advise focusing on fruits, veggies, and whole grains. They say to stay away from processed foods too.

• #105 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  As excessive alcohol consumption can weaken an individual’s immune system, it is recommended to limit its consumption to reduce the risk of lymphoma. […] Certain infections associated with lymphoma, such as Epstein-Barr virus or Hepatitis C virus (HCV), can hamper the healthy DNA of the cells; treating them can help in potential lymphoma prevention as well. […] Minimizing excessive exposure to toxic chemicals, such as benzene, can also help reduce the risk of developing lymphoma. […] As radiation exposure can damage the DNA structure of healthy cells, leading to an increased risk of lymphoma, it is often recommended to limit radiation exposure as much as possible. […] As lymphoma affects the lymphatic system, an important part of the immune system, experts advise making efforts to maintain a healthy immune system for potential lymphoma prevention.

• #106 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  As excessive alcohol consumption can weaken an individual’s immune system, it is recommended to limit its consumption to reduce the risk of lymphoma. […] Certain infections associated with lymphoma, such as Epstein-Barr virus or Hepatitis C virus (HCV), can hamper the healthy DNA of the cells; treating them can help in potential lymphoma prevention as well. […] Minimizing excessive exposure to toxic chemicals, such as benzene, can also help reduce the risk of developing lymphoma. […] As radiation exposure can damage the DNA structure of healthy cells, leading to an increased risk of lymphoma, it is often recommended to limit radiation exposure as much as possible. […] As lymphoma affects the lymphatic system, an important part of the immune system, experts advise making efforts to maintain a healthy immune system for potential lymphoma prevention.

• #107 Non-Hodgkin Lymphoma

  https://www.health.ny.gov/statistics/cancer/registry/abouts/nhl.htm

  What can I do to reduce my chances of getting non-Hodgkin lymphoma? To help reduce the risk of getting non-Hodgkin lymphoma: Individuals with suppressed immune systems due to HIV/AIDS should talk with their health care provider about treatment and risk for non-Hodgkin lymphoma. Individuals with autoimmune disorders should talk with their health care providers about their risk for getting non-Hodgkin lymphoma. Know your family history and discuss any concerns with your health care provider. […] How else can I reduce my risk for cancer? The following may help reduce the risk of developing cancer: Be aware of workplace health and safety rules and follow them. Limit alcohol use. Choose a healthy diet to achieve and maintain a healthy weight. Eat more vegetables, fruits and whole grains and eat less red and processed (e.g., bacon, sausage, luncheon meat, hot dogs) meats. These actions may reduce the risk of developing many cancers as well as other diseases. Exercise regularly. Do not smoke. If you currently smoke, quit. Avoid exposure to secondhand smoke. For more information on quitting smoking, visit the NYS Smoker’s Quitline at www.nysmokefree.com or call 1-866-NY-QUITS. Discuss the risks and benefits of medical imaging, such as CT scans, with your health care provider to avoid unnecessary exposure to ionizing radiation. This is particularly important for children. Talk with your health care provider about recommended cancer screenings.

• #108 Non-Hodgkin Lymphoma

  https://www.health.ny.gov/statistics/cancer/registry/abouts/nhl.htm

  What can I do to reduce my chances of getting non-Hodgkin lymphoma? To help reduce the risk of getting non-Hodgkin lymphoma: Individuals with suppressed immune systems due to HIV/AIDS should talk with their health care provider about treatment and risk for non-Hodgkin lymphoma. Individuals with autoimmune disorders should talk with their health care providers about their risk for getting non-Hodgkin lymphoma. Know your family history and discuss any concerns with your health care provider. […] How else can I reduce my risk for cancer? The following may help reduce the risk of developing cancer: Be aware of workplace health and safety rules and follow them. Limit alcohol use. Choose a healthy diet to achieve and maintain a healthy weight. Eat more vegetables, fruits and whole grains and eat less red and processed (e.g., bacon, sausage, luncheon meat, hot dogs) meats. These actions may reduce the risk of developing many cancers as well as other diseases. Exercise regularly. Do not smoke. If you currently smoke, quit. Avoid exposure to secondhand smoke. For more information on quitting smoking, visit the NYS Smoker’s Quitline at www.nysmokefree.com or call 1-866-NY-QUITS. Discuss the risks and benefits of medical imaging, such as CT scans, with your health care provider to avoid unnecessary exposure to ionizing radiation. This is particularly important for children. Talk with your health care provider about recommended cancer screenings.

• #109 Lymphoma: Symptoms, Causes and Treatment

  https://my.clevelandclinic.org/health/diseases/22225-lymphoma

  Researchers continue to identify lymphoma risk factors. Theres reason to believe certain viruses and family medical history increase the risk of developing lymphoma. Talk to your healthcare provider if you think your medical history or family medical history might increase your risk of developing lymphoma.

• #110 Lymphoma | Nutrition Guide for Clinicians

  https://nutritionguide.pcrm.org/nutritionguide/view/Nutrition_Guide_for_Clinicians/1342083/all/Lymphoma

  Increasing intake of fruits and vegetables. When the highest category of fruit and vegetable intake was compared with the lowest, a meta-analysis found a roughly 20% lower risk for NHL in high consumers, a difference that appeared to be due mainly to vegetable rather than fruit intake. […] High vitamin A and C intakes. The observed benefits of fruits and vegetables in relation to lymphoma prevention may be in part attributable to vitamin C and pro-vitamin A carotenoids. […] A gluten-free diet for individuals with celiac disease. Patients with celiac disease have a 25% greater risk for malignancy overall, a 60% greater risk for gastrointestinal malignancy, a 14 times greater risk for small intestine carcinoma, and a 6-9 times greater risk for NHL when compared with the general population. […] Maintenance of a healthy weight. Studies suggest that being significantly overweight or obese may increase the risk for lymphomas.

• #111 Lymphoma | Nutrition Guide for Clinicians

  https://nutritionguide.pcrm.org/nutritionguide/view/Nutrition_Guide_for_Clinicians/1342083/all/Lymphoma

  Increasing intake of fruits and vegetables. When the highest category of fruit and vegetable intake was compared with the lowest, a meta-analysis found a roughly 20% lower risk for NHL in high consumers, a difference that appeared to be due mainly to vegetable rather than fruit intake. […] High vitamin A and C intakes. The observed benefits of fruits and vegetables in relation to lymphoma prevention may be in part attributable to vitamin C and pro-vitamin A carotenoids. […] A gluten-free diet for individuals with celiac disease. Patients with celiac disease have a 25% greater risk for malignancy overall, a 60% greater risk for gastrointestinal malignancy, a 14 times greater risk for small intestine carcinoma, and a 6-9 times greater risk for NHL when compared with the general population. […] Maintenance of a healthy weight. Studies suggest that being significantly overweight or obese may increase the risk for lymphomas.

• #112 Prevention & Risk Factors | Saint Francis Health System

  https://www.saintfrancis.com/services/cancer-care/conditions-treatments/non-hodgkins-lymphoma/prevention-risk-factors

  The cause of non-Hodgkins lymphoma is unknown. Mutations in DNA that occur after birth may be related to this cancer. These mutations can occur as a result of exposure to radiation or cancer-causing chemicals. It may also occur with age or for no apparent reason. The cancer care specialists at the Saint Francis Cancer Center want to educate you on prevention and risk factors associated with this type of lymphoma. […] There are no guidelines for preventing non-Hodgkins lymphoma. To reduce your risk, avoid exposure to chemicals such as herbicides, pesticides and benzene. If you have celiac disease (gluten intolerance), maintain your gluten-free diet. This diet will minimize the stimulation of your immune system by exposure to gluten.

• #113 Prevention & Risk Factors | Saint Francis Health System

  https://www.saintfrancis.com/services/cancer-care/conditions-treatments/non-hodgkins-lymphoma/prevention-risk-factors

  The cause of non-Hodgkins lymphoma is unknown. Mutations in DNA that occur after birth may be related to this cancer. These mutations can occur as a result of exposure to radiation or cancer-causing chemicals. It may also occur with age or for no apparent reason. The cancer care specialists at the Saint Francis Cancer Center want to educate you on prevention and risk factors associated with this type of lymphoma. […] There are no guidelines for preventing non-Hodgkins lymphoma. To reduce your risk, avoid exposure to chemicals such as herbicides, pesticides and benzene. If you have celiac disease (gluten intolerance), maintain your gluten-free diet. This diet will minimize the stimulation of your immune system by exposure to gluten.

• #114 Lymphoma | Nutrition Guide for Clinicians

  https://nutritionguide.pcrm.org/nutritionguide/view/Nutrition_Guide_for_Clinicians/1342083/all/Lymphoma

  Increasing intake of fruits and vegetables. When the highest category of fruit and vegetable intake was compared with the lowest, a meta-analysis found a roughly 20% lower risk for NHL in high consumers, a difference that appeared to be due mainly to vegetable rather than fruit intake. […] High vitamin A and C intakes. The observed benefits of fruits and vegetables in relation to lymphoma prevention may be in part attributable to vitamin C and pro-vitamin A carotenoids. […] A gluten-free diet for individuals with celiac disease. Patients with celiac disease have a 25% greater risk for malignancy overall, a 60% greater risk for gastrointestinal malignancy, a 14 times greater risk for small intestine carcinoma, and a 6-9 times greater risk for NHL when compared with the general population. […] Maintenance of a healthy weight. Studies suggest that being significantly overweight or obese may increase the risk for lymphomas.

• #115 Lymphoma: Symptoms, Causes and Treatment

  https://my.clevelandclinic.org/health/diseases/22225-lymphoma

  Researchers continue to identify lymphoma risk factors. Theres reason to believe certain viruses and family medical history increase the risk of developing lymphoma. Talk to your healthcare provider if you think your medical history or family medical history might increase your risk of developing lymphoma.

• #116 Lymphoma Awareness and Prevention | Lymphoma | UT Southwestern Medical Center

  https://utswmed.org/conditions-treatments/lymphoma/lymphoma-awareness-and-prevention/

  While the risk factors and causes of lymphoma arent yet fully understood, its important to be aware of the suspected risk factors, especially for people who have a family history of the disease. […] For non-Hodgkin lymphoma (NHL), suspected risk factors include: […] Suspected risk factors for Hodgkin lymphoma (HL) include:

• #117 Non-Hodgkin Lymphoma

  https://www.health.ny.gov/statistics/cancer/registry/abouts/nhl.htm

  What can I do to reduce my chances of getting non-Hodgkin lymphoma? To help reduce the risk of getting non-Hodgkin lymphoma: Individuals with suppressed immune systems due to HIV/AIDS should talk with their health care provider about treatment and risk for non-Hodgkin lymphoma. Individuals with autoimmune disorders should talk with their health care providers about their risk for getting non-Hodgkin lymphoma. Know your family history and discuss any concerns with your health care provider. […] How else can I reduce my risk for cancer? The following may help reduce the risk of developing cancer: Be aware of workplace health and safety rules and follow them. Limit alcohol use. Choose a healthy diet to achieve and maintain a healthy weight. Eat more vegetables, fruits and whole grains and eat less red and processed (e.g., bacon, sausage, luncheon meat, hot dogs) meats. These actions may reduce the risk of developing many cancers as well as other diseases. Exercise regularly. Do not smoke. If you currently smoke, quit. Avoid exposure to secondhand smoke. For more information on quitting smoking, visit the NYS Smoker’s Quitline at www.nysmokefree.com or call 1-866-NY-QUITS. Discuss the risks and benefits of medical imaging, such as CT scans, with your health care provider to avoid unnecessary exposure to ionizing radiation. This is particularly important for children. Talk with your health care provider about recommended cancer screenings.

• #118 Reducing your risk for Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing Hodgkin lymphoma (HL) by doing the following. […] You can lower your risk of getting HIV infection by avoiding activities that are known to increase the risk of HIV, such as intravenous drug use or having sex without a condom with many partners. […] To help reduce the risk of Epstein-Barr virus (EBV) infection, dont share drinks, food, utensils or toothbrushes. […] Smoking tobacco may increase your risk of developing HL. If you smoke, get help to quit. […] Some people can have a higher than average risk for HL. Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for HL. Your doctor will recommend what tests you should have and how often you should have them. […] Learn how cancer can be prevented and what you can do to reduce your risk.

• #119 „Prevention of Lymphoma | Prevention of Hodgkin’s Lymphoma „

  https://www.patientsengage.com/conditions/lymphoma/prevention?page=2

  Prevention of Hodgkin’s Lymphoma The only way to prevent it is by lowering one’s risk factors such as obesity, HIV etc. […] Prevention of non-Hodgkin’s Lymphoma The only way to prevent it is by lowering one’s risk factors such as obesity, HIV, HTLV-1 infection etc. […] Prevention of Burkitt’s Lymphoma Some risk factors associated with the Sporadic form can be lowered, most particularly lifestyle behaviors that increase the risk of HIV infection.

• #120 Non-Hodgkin Lymphoma

  https://www.health.ny.gov/statistics/cancer/registry/abouts/nhl.htm

  What can I do to reduce my chances of getting non-Hodgkin lymphoma? To help reduce the risk of getting non-Hodgkin lymphoma: Individuals with suppressed immune systems due to HIV/AIDS should talk with their health care provider about treatment and risk for non-Hodgkin lymphoma. Individuals with autoimmune disorders should talk with their health care providers about their risk for getting non-Hodgkin lymphoma. Know your family history and discuss any concerns with your health care provider. […] How else can I reduce my risk for cancer? The following may help reduce the risk of developing cancer: Be aware of workplace health and safety rules and follow them. Limit alcohol use. Choose a healthy diet to achieve and maintain a healthy weight. Eat more vegetables, fruits and whole grains and eat less red and processed (e.g., bacon, sausage, luncheon meat, hot dogs) meats. These actions may reduce the risk of developing many cancers as well as other diseases. Exercise regularly. Do not smoke. If you currently smoke, quit. Avoid exposure to secondhand smoke. For more information on quitting smoking, visit the NYS Smoker’s Quitline at www.nysmokefree.com or call 1-866-NY-QUITS. Discuss the risks and benefits of medical imaging, such as CT scans, with your health care provider to avoid unnecessary exposure to ionizing radiation. This is particularly important for children. Talk with your health care provider about recommended cancer screenings.

• #121 Non-Hodgkin Lymphoma

  https://www.health.ny.gov/statistics/cancer/registry/abouts/nhl.htm

  What can I do to reduce my chances of getting non-Hodgkin lymphoma? To help reduce the risk of getting non-Hodgkin lymphoma: Individuals with suppressed immune systems due to HIV/AIDS should talk with their health care provider about treatment and risk for non-Hodgkin lymphoma. Individuals with autoimmune disorders should talk with their health care providers about their risk for getting non-Hodgkin lymphoma. Know your family history and discuss any concerns with your health care provider. […] How else can I reduce my risk for cancer? The following may help reduce the risk of developing cancer: Be aware of workplace health and safety rules and follow them. Limit alcohol use. Choose a healthy diet to achieve and maintain a healthy weight. Eat more vegetables, fruits and whole grains and eat less red and processed (e.g., bacon, sausage, luncheon meat, hot dogs) meats. These actions may reduce the risk of developing many cancers as well as other diseases. Exercise regularly. Do not smoke. If you currently smoke, quit. Avoid exposure to secondhand smoke. For more information on quitting smoking, visit the NYS Smoker’s Quitline at www.nysmokefree.com or call 1-866-NY-QUITS. Discuss the risks and benefits of medical imaging, such as CT scans, with your health care provider to avoid unnecessary exposure to ionizing radiation. This is particularly important for children. Talk with your health care provider about recommended cancer screenings.

• #122 Non Hodgkin’s Lymphoma Prevention Strategies – Acibadem Health Point – ACIBADEM Hospitals – Acibadem Health Group

  https://www.acibademhealthpoint.com/non-hodgkins-lymphoma-prevention-strategies/

  Studies in the Journal of Occupational and Environmental Medicine point to pesticides as a lymphoma risk. They show a clear link. Being careful, like wearing protective clothes and picking organic, lowers this risk. […] It’s key to find lymphoma early for better prevention. Having check-ups often and checking genes are big helps. They spot risks early and make doing something about it easier. […] Seeing the doctor often is great for stopping lymphoma. Doctors can find signs early, helping you get care quickly. Keeping up with check-ups helps catch any problems fast. […] If lymphoma runs in your family, genetic testing is important. It looks for signs in your genes that mean a higher risk. Combining this with regular check-ups boosts finding problems early. […] Eating right is key to staying healthy and avoiding illnesses like lymphoma. Health experts advise focusing on fruits, veggies, and whole grains. They say to stay away from processed foods too.

• #123 Prevention and management of secondary central nervous system lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9973486/

  The addition of lenalidomide to R-CHOP in DLBCL showed a lower than expected rate of CNS relapse in a retrospective analysis of 136 patients from phase II trials, with a 2-year CNS relapse rate of 5% in high-risk patients. […] We need to continue to explore more specific methods of identifying patients at highest risk of CNS relapse, and to investigate more effective prophylactic strategies. […] The incorporation of novel agents (immunomodulatory agents, BTK inhibitors) into frontline standard immunochemotherapy might reduce the number of CNS events, although this deserves further study in prospective trials.

• #124 Hodgkin Lymphoma Screening/Prevention | Nebraska Hematology Oncology – Cancer Care Treatment Blood Disorders Clinical Trials Lincoln Nebraska (NE)

  https://www.yourcancercare.com/types-of-cancer/hodgkin-lymphoma/hodgkin-lymphoma-screeningprevention

  Information about the prevention of cancer and the science of screening appropriate individuals at high-risk of developing cancer is gaining interest. […] Cancer is largely a preventable illness. Two-thirds of cancer deaths in the U.S. can be linked to tobacco use, poor diet, obesity, and lack of exercise. All of these factors can be modified. Nevertheless, an awareness of the opportunity to prevent cancer through changes in lifestyle is still under-appreciated. The overwhelming majority of cases of Hodgkins disease cannot be prevented since we do not know the cause. […] Scientists around the world have been working on vaccine strategies against Epstein-Barr virus associated diseases. This work has been hampered by an inability to identify the characteristics of the virus when it remains dormant in the body. However, there is currently some optimism that vaccine trials aimed at controlling infectious mononucleosis, post-transplant lymphoproliferative disease, nasopharyngeal carcinoma and Hodgkins disease may soon be justified.

• #125 Hodgkin Lymphoma Screening/Prevention | Nebraska Hematology Oncology – Cancer Care Treatment Blood Disorders Clinical Trials Lincoln Nebraska (NE)

  https://www.yourcancercare.com/types-of-cancer/hodgkin-lymphoma/hodgkin-lymphoma-screeningprevention

  Information about the prevention of cancer and the science of screening appropriate individuals at high-risk of developing cancer is gaining interest. […] Cancer is largely a preventable illness. Two-thirds of cancer deaths in the U.S. can be linked to tobacco use, poor diet, obesity, and lack of exercise. All of these factors can be modified. Nevertheless, an awareness of the opportunity to prevent cancer through changes in lifestyle is still under-appreciated. The overwhelming majority of cases of Hodgkins disease cannot be prevented since we do not know the cause. […] Scientists around the world have been working on vaccine strategies against Epstein-Barr virus associated diseases. This work has been hampered by an inability to identify the characteristics of the virus when it remains dormant in the body. However, there is currently some optimism that vaccine trials aimed at controlling infectious mononucleosis, post-transplant lymphoproliferative disease, nasopharyngeal carcinoma and Hodgkins disease may soon be justified.

• #126 Prevention and management of secondary central nervous system lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9973486/

  The addition of lenalidomide to R-CHOP in DLBCL showed a lower than expected rate of CNS relapse in a retrospective analysis of 136 patients from phase II trials, with a 2-year CNS relapse rate of 5% in high-risk patients. […] We need to continue to explore more specific methods of identifying patients at highest risk of CNS relapse, and to investigate more effective prophylactic strategies. […] The incorporation of novel agents (immunomodulatory agents, BTK inhibitors) into frontline standard immunochemotherapy might reduce the number of CNS events, although this deserves further study in prospective trials.

• #127 Hodgkin Lymphoma Screening/Prevention | Nebraska Hematology Oncology – Cancer Care Treatment Blood Disorders Clinical Trials Lincoln Nebraska (NE)

  https://www.yourcancercare.com/types-of-cancer/hodgkin-lymphoma/hodgkin-lymphoma-screeningprevention

  Information about the prevention of cancer and the science of screening appropriate individuals at high-risk of developing cancer is gaining interest. […] Cancer is largely a preventable illness. Two-thirds of cancer deaths in the U.S. can be linked to tobacco use, poor diet, obesity, and lack of exercise. All of these factors can be modified. Nevertheless, an awareness of the opportunity to prevent cancer through changes in lifestyle is still under-appreciated. The overwhelming majority of cases of Hodgkins disease cannot be prevented since we do not know the cause. […] Scientists around the world have been working on vaccine strategies against Epstein-Barr virus associated diseases. This work has been hampered by an inability to identify the characteristics of the virus when it remains dormant in the body. However, there is currently some optimism that vaccine trials aimed at controlling infectious mononucleosis, post-transplant lymphoproliferative disease, nasopharyngeal carcinoma and Hodgkins disease may soon be justified.

• #128 Prevention and management of secondary central nervous system lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9973486/

  The addition of lenalidomide to R-CHOP in DLBCL showed a lower than expected rate of CNS relapse in a retrospective analysis of 136 patients from phase II trials, with a 2-year CNS relapse rate of 5% in high-risk patients. […] We need to continue to explore more specific methods of identifying patients at highest risk of CNS relapse, and to investigate more effective prophylactic strategies. […] The incorporation of novel agents (immunomodulatory agents, BTK inhibitors) into frontline standard immunochemotherapy might reduce the number of CNS events, although this deserves further study in prospective trials.

• #129 Should We Abandon CNS Prophylaxis for Aggressive Lymphomas?

  https://www.uvaphysicianresource.com/cns-prophylaxis-lymphomas/

  Testicular involvement, non-GCB subtype, and a high extranodal burden predicted increased CNS risk despite MTX-based prophylaxis by either route. […] Portell notes that some oncologists have abandoned CNS prophylaxis with MTX. It still plays a role in certain patients, he shares in an editorial he authored in the journal Blood. […] With the currently available data, intravenous HD-MTX should be limited to end of therapy and to patients with the highest risk, Portell writes. […] MTX therapy still offers protection for patients with extranodal disease in their testes, kidneys, or adrenal glands. […] Finally, anthracycline-based immunochemotherapy should always take priority over CNS prophylaxis. […] Therapies directed at the biology of DLBCL will one day likely replace MTX-based strategies for CNS prophylaxis. […] He adds that ibrutinib, lenalidomide, and other agents may be effective in preventing secondary CNS progression.

• #130 Prevention and management of secondary central nervous system lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9973486/

  The addition of lenalidomide to R-CHOP in DLBCL showed a lower than expected rate of CNS relapse in a retrospective analysis of 136 patients from phase II trials, with a 2-year CNS relapse rate of 5% in high-risk patients. […] We need to continue to explore more specific methods of identifying patients at highest risk of CNS relapse, and to investigate more effective prophylactic strategies. […] The incorporation of novel agents (immunomodulatory agents, BTK inhibitors) into frontline standard immunochemotherapy might reduce the number of CNS events, although this deserves further study in prospective trials.

• #131 Should We Abandon CNS Prophylaxis for Aggressive Lymphomas?

  https://www.uvaphysicianresource.com/cns-prophylaxis-lymphomas/

  Testicular involvement, non-GCB subtype, and a high extranodal burden predicted increased CNS risk despite MTX-based prophylaxis by either route. […] Portell notes that some oncologists have abandoned CNS prophylaxis with MTX. It still plays a role in certain patients, he shares in an editorial he authored in the journal Blood. […] With the currently available data, intravenous HD-MTX should be limited to end of therapy and to patients with the highest risk, Portell writes. […] MTX therapy still offers protection for patients with extranodal disease in their testes, kidneys, or adrenal glands. […] Finally, anthracycline-based immunochemotherapy should always take priority over CNS prophylaxis. […] Therapies directed at the biology of DLBCL will one day likely replace MTX-based strategies for CNS prophylaxis. […] He adds that ibrutinib, lenalidomide, and other agents may be effective in preventing secondary CNS progression.

• #132

  https://winshipcancer.emory.edu/cancer-types-and-treatments/lymphoma/signs-and-symptoms.php

  As the only NCI-designated Comprehensive Cancer Center in Georgia, Winship Cancer Institute of Emory University is pioneering the research in lymphoma prevention, screening and treatment. […] Winship is collaborating with seven other premier cancer centers throughout the country on the Lymphoma Epidemiology of Outcomes (LEO) study. The groundbreaking program is studying 12,000 participants to examine ways to screen for, and prevent, non-Hodgkins lymphoma by looking at biological markers that may be associated with the disease.

• #133 Recent updates on central nervous system prophylaxis in patients with high-risk diffuse large B-cell lymphoma | Experimental Hematology & Oncology | Full Text

  https://ehoonline.biomedcentral.com/articles/10.1186/s40164-023-00467-2

  While this will require further investigation and validation in larger cohorts, perhaps a genomic risk assessment with a selected genetic panel can be developed to identify patients who are at high risk of CNS relapses, warranting CNS prophylaxis. […] Overall, risks of a combined approach, both in terms of drug toxicities and the additional procedural risks of a lumbar puncture, may not be justified when the utility of either IT MTX or IV HD-MTX is not clear. […] Given the above, the utility of IV HD-MTX in CNS prophylaxis has been cast into doubt. […] A randomized controlled trial remains the gold standard to conclusively demonstrate the efficacy of IV HD-MTX but this is inherently challenging to conduct given the low incidence of CNS relapses.

• #134

  https://winshipcancer.emory.edu/cancer-types-and-treatments/lymphoma/signs-and-symptoms.php

  As the only NCI-designated Comprehensive Cancer Center in Georgia, Winship Cancer Institute of Emory University is pioneering the research in lymphoma prevention, screening and treatment. […] Winship is collaborating with seven other premier cancer centers throughout the country on the Lymphoma Epidemiology of Outcomes (LEO) study. The groundbreaking program is studying 12,000 participants to examine ways to screen for, and prevent, non-Hodgkins lymphoma by looking at biological markers that may be associated with the disease.

• #135 Recent updates on central nervous system prophylaxis in patients with high-risk diffuse large B-cell lymphoma | Experimental Hematology & Oncology | Full Text

  https://ehoonline.biomedcentral.com/articles/10.1186/s40164-023-00467-2

  While this will require further investigation and validation in larger cohorts, perhaps a genomic risk assessment with a selected genetic panel can be developed to identify patients who are at high risk of CNS relapses, warranting CNS prophylaxis. […] Overall, risks of a combined approach, both in terms of drug toxicities and the additional procedural risks of a lumbar puncture, may not be justified when the utility of either IT MTX or IV HD-MTX is not clear. […] Given the above, the utility of IV HD-MTX in CNS prophylaxis has been cast into doubt. […] A randomized controlled trial remains the gold standard to conclusively demonstrate the efficacy of IV HD-MTX but this is inherently challenging to conduct given the low incidence of CNS relapses.

• #136 Recent updates on central nervous system prophylaxis in patients with high-risk diffuse large B-cell lymphoma | Experimental Hematology & Oncology | Full Text

  https://ehoonline.biomedcentral.com/articles/10.1186/s40164-023-00467-2

  Practices differ globally regarding the use of CNS prophylaxis in patients with DLBCL. […] While intravenous high-dose methotrexate (IV HD-MTX) appears to be a preferred option across various guidelines, it utilizes more resources given the need for inpatient monitoring, hydration, alkalinization of urine and drug clearance. […] In settings where resources are limited or if patients are not fit for IV HD-MTX, intrathecal methotrexate (IT MTX) remains an alternative option. […] Importantly, high risk anatomical sites such as breast and testis involvement as well as consideration of cell of origin have a significant impact in prognosticating for CNS relapses. […] The concept of CNS tropism that may be identified via biological markers is an ongoing area of research. […] Therefore, risk assessment of CNS relapse for DLBCL patients should perhaps utilize the combination of CNS-IPI score and COO.

• #137 Review of Natural Compounds for the Management and Prevention of Lymphoma

  https://www.mdpi.com/2227-9717/8/9/1164

  Lymphoma is a type of blood cancer that can be categorized into two types-Hodgkin lymphoma (HL) and Non-Hodgkin lymphoma (NHL). […] Although conventional therapy has stridden forward over recent decades, its adverse effects are still a hurdle to be solved. […] Thus, to help researchers develop better lymphoma treatment, this study aims to review the systematic anticancer data for natural products and their compounds. […] A variety of natural products showed anticancerous effects on lymphoma by regulation of intracellular mechanisms including apoptosis as well as cell cycle arrest. […] As these results shed light on the potential to substitute conventional therapy with natural products, it may become a promising strategy for lymphoma treatment in the near future. […] The main purpose of this study is to provide researchers with systematic data about natural products for lymphoma treatment to inspire the development of novel drugs for lymphoma.

• #138 Review of Natural Compounds for the Management and Prevention of Lymphoma

  https://www.mdpi.com/2227-9717/8/9/1164

  In this study, anticancerous abilities of ninety natural compounds against lymphoma were reviewed. Each natural compound regulated diverse mechanisms including antiproliferation, apoptosis, and cell cycle arrest. These have a potential to treat diverse types of lymphoma. If further studies were involved from now on, natural compounds may become a promising strategy for lymphoma instead of conventional treatment.

• #139 Review of Natural Compounds for the Management and Prevention of Lymphoma

  https://www.mdpi.com/2227-9717/8/9/1164

  Lymphoma is a type of blood cancer that can be categorized into two types-Hodgkin lymphoma (HL) and Non-Hodgkin lymphoma (NHL). […] Although conventional therapy has stridden forward over recent decades, its adverse effects are still a hurdle to be solved. […] Thus, to help researchers develop better lymphoma treatment, this study aims to review the systematic anticancer data for natural products and their compounds. […] A variety of natural products showed anticancerous effects on lymphoma by regulation of intracellular mechanisms including apoptosis as well as cell cycle arrest. […] As these results shed light on the potential to substitute conventional therapy with natural products, it may become a promising strategy for lymphoma treatment in the near future. […] The main purpose of this study is to provide researchers with systematic data about natural products for lymphoma treatment to inspire the development of novel drugs for lymphoma.

• #140 Review of Natural Compounds for the Management and Prevention of Lymphoma

  https://www.mdpi.com/2227-9717/8/9/1164

  In this study, anticancerous abilities of ninety natural compounds against lymphoma were reviewed. Each natural compound regulated diverse mechanisms including antiproliferation, apoptosis, and cell cycle arrest. These have a potential to treat diverse types of lymphoma. If further studies were involved from now on, natural compounds may become a promising strategy for lymphoma instead of conventional treatment.

• #141 Review of Natural Compounds for the Management and Prevention of Lymphoma

  https://www.mdpi.com/2227-9717/8/9/1164

  Lymphoma is a type of blood cancer that can be categorized into two types-Hodgkin lymphoma (HL) and Non-Hodgkin lymphoma (NHL). […] Although conventional therapy has stridden forward over recent decades, its adverse effects are still a hurdle to be solved. […] Thus, to help researchers develop better lymphoma treatment, this study aims to review the systematic anticancer data for natural products and their compounds. […] A variety of natural products showed anticancerous effects on lymphoma by regulation of intracellular mechanisms including apoptosis as well as cell cycle arrest. […] As these results shed light on the potential to substitute conventional therapy with natural products, it may become a promising strategy for lymphoma treatment in the near future. […] The main purpose of this study is to provide researchers with systematic data about natural products for lymphoma treatment to inspire the development of novel drugs for lymphoma.

• #142

  https://winshipcancer.emory.edu/cancer-types-and-treatments/lymphoma/prevention.php

  There is no guaranteed way to prevent lymphoma. And while the causes of Hodgkin and non-Hodgkin lymphoma are still being studied, you can lower your risk of getting the disease. […] Because lymphoma affects your immune system, there are steps you can take to prevent it, such as limiting your risk of contracting infections and making lifestyle changes that help you maintain a healthy immune system. You can also reduce your risk if you: […] Besides researching new therapies for treating lymphoma, Winship Cancer Institute is also collaborating on a study to determine how to prevent non-Hodgkin lymphoma.

• #143 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  There is no sure way to prevent non-Hodgkin lymphoma (NHL). But there are some things you can do that might help lower your risk. […] Most people with NHL have no risk factors that can be changed, so there is no way to protect against these lymphomas. But you may be able to lower your risk by limiting your risk of certain infections and doing what you can to maintain a healthy immune system. […] Infection with HIV, the virus that causes AIDS, is known to increase the risk of NHL, so one way to limit your risk is to avoid known risk factors for HIV, such as intravenous drug use or unprotected sex with many partners. […] Preventing the spread of the human T-cell lymphotropic virus (HTLV-1) could have a great impact on non-Hodgkin lymphoma in areas of the world where this virus is common, such as Japan and the Caribbean region.

• #144 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  Helicobacter pylori (H. pylori) infection has been linked to some lymphomas of the stomach. Treating H. pylori infections with antibiotics and antacids may lower this risk, but the benefit of this strategy has not been proven yet. […] Some studies have suggested that having excess body weight may increase your risk of non-Hodgkin lymphoma. Staying at a healthy weight, keeping physically active, and following a healthy eating pattern that includes plenty of fruits, vegetables, and whole grains, and that limits or avoids red and processed meats, sugary drinks, and highly processed foods may help protect against lymphoma, but more research is needed to confirm this.

• #145 Lymphoma prevention and early detection: What you need to know – The Times of India

  https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/lymphoma-prevention-and-early-detection-what-you-need-to-know/articleshow/106182611.cms

  Early visit to an oncologist and never neglecting a suspicious symptom helps a long way in the disease management. Staying at a healthy weight, keeping physically active and following a good diet that includes plenty of fruits, vegetables, and whole grains, and that limits or avoids red and processed meats, sugary drinks, and highly processed foods may help protect against lymphoma.

• #146 Can Non-Hodgkin Lymphoma Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/non-hodgkin-lymphoma/causes-risks-prevention/prevention.html

  There is no sure way to prevent non-Hodgkin lymphoma (NHL). But there are some things you can do that might help lower your risk. […] Most people with NHL have no risk factors that can be changed, so there is no way to protect against these lymphomas. But you may be able to lower your risk by limiting your risk of certain infections and doing what you can to maintain a healthy immune system. […] Infection with HIV, the virus that causes AIDS, is known to increase the risk of NHL, so one way to limit your risk is to avoid known risk factors for HIV, such as intravenous drug use or unprotected sex with many partners. […] Preventing the spread of the human T-cell lymphotropic virus (HTLV-1) could have a great impact on non-Hodgkin lymphoma in areas of the world where this virus is common, such as Japan and the Caribbean region.

• #147 Reducing your risk for Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing Hodgkin lymphoma (HL) by doing the following. […] You can lower your risk of getting HIV infection by avoiding activities that are known to increase the risk of HIV, such as intravenous drug use or having sex without a condom with many partners. […] To help reduce the risk of Epstein-Barr virus (EBV) infection, dont share drinks, food, utensils or toothbrushes. […] Smoking tobacco may increase your risk of developing HL. If you smoke, get help to quit. […] Some people can have a higher than average risk for HL. Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for HL. Your doctor will recommend what tests you should have and how often you should have them. […] Learn how cancer can be prevented and what you can do to reduce your risk.

• #148 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  Unfortunately, there is no decisive answer on how to prevent lymphoma. The main reason for this is that we do not have complete information about the exact causes of lymphoma. […] However, understanding lymphoma risk factors can play a significant role in reducing the chances of developing lymphoma. […] Though there are no definitive ways of preventing lymphoma, adopting certain measures can surely help reduce the risk of developing cancer. […] Smoking can have an adverse effect on the genetics of healthy cells, increasing the chances of cancer development. Thus, it is recommended to quit smoking as a potential lymphoma cancer prevention strategy. […] A potential lymphoma prevention diet should include a balance of fruits, whole grains, and nuts while limiting the intake of processed meats and sugary drinks.

• #149 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  As excessive alcohol consumption can weaken an individual’s immune system, it is recommended to limit its consumption to reduce the risk of lymphoma. […] Certain infections associated with lymphoma, such as Epstein-Barr virus or Hepatitis C virus (HCV), can hamper the healthy DNA of the cells; treating them can help in potential lymphoma prevention as well. […] Minimizing excessive exposure to toxic chemicals, such as benzene, can also help reduce the risk of developing lymphoma. […] As radiation exposure can damage the DNA structure of healthy cells, leading to an increased risk of lymphoma, it is often recommended to limit radiation exposure as much as possible. […] As lymphoma affects the lymphatic system, an important part of the immune system, experts advise making efforts to maintain a healthy immune system for potential lymphoma prevention.

• #150 Reducing your risk for non-Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/non-hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing non-Hodgkin lymphoma (NHL) by doing the following. […] Avoid or lower your long-term exposure to pesticides. […] You may lower your risk by having a healthy body weight. […] Follow occupational and safety guidelines when working with hazardous chemicals. […] Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for NHL.

• #151 Lymphoma Prevention Tips & Risk Factors | HCG Oncology

  http://www.hcgoncology.com/types-of-cancers/lymphoma-prevention/

  As excessive alcohol consumption can weaken an individual’s immune system, it is recommended to limit its consumption to reduce the risk of lymphoma. […] Certain infections associated with lymphoma, such as Epstein-Barr virus or Hepatitis C virus (HCV), can hamper the healthy DNA of the cells; treating them can help in potential lymphoma prevention as well. […] Minimizing excessive exposure to toxic chemicals, such as benzene, can also help reduce the risk of developing lymphoma. […] As radiation exposure can damage the DNA structure of healthy cells, leading to an increased risk of lymphoma, it is often recommended to limit radiation exposure as much as possible. […] As lymphoma affects the lymphatic system, an important part of the immune system, experts advise making efforts to maintain a healthy immune system for potential lymphoma prevention.

• #152 Prevention & Risk Factors | Saint Francis Health System

  https://www.saintfrancis.com/services/cancer-care/conditions-treatments/non-hodgkins-lymphoma/prevention-risk-factors

  The cause of non-Hodgkins lymphoma is unknown. Mutations in DNA that occur after birth may be related to this cancer. These mutations can occur as a result of exposure to radiation or cancer-causing chemicals. It may also occur with age or for no apparent reason. The cancer care specialists at the Saint Francis Cancer Center want to educate you on prevention and risk factors associated with this type of lymphoma. […] There are no guidelines for preventing non-Hodgkins lymphoma. To reduce your risk, avoid exposure to chemicals such as herbicides, pesticides and benzene. If you have celiac disease (gluten intolerance), maintain your gluten-free diet. This diet will minimize the stimulation of your immune system by exposure to gluten.

• #153 Reducing your risk for non-Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/non-hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing non-Hodgkin lymphoma (NHL) by doing the following. […] Avoid or lower your long-term exposure to pesticides. […] You may lower your risk by having a healthy body weight. […] Follow occupational and safety guidelines when working with hazardous chemicals. […] Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for NHL.

• #154 Reducing your risk for Hodgkin lymphoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/hodgkin-lymphoma/risks/reducing-your-risk

  You may lower your risk of developing Hodgkin lymphoma (HL) by doing the following. […] You can lower your risk of getting HIV infection by avoiding activities that are known to increase the risk of HIV, such as intravenous drug use or having sex without a condom with many partners. […] To help reduce the risk of Epstein-Barr virus (EBV) infection, dont share drinks, food, utensils or toothbrushes. […] Smoking tobacco may increase your risk of developing HL. If you smoke, get help to quit. […] Some people can have a higher than average risk for HL. Talk to your doctor about your risk. If you are at higher than average risk, you may need to visit your doctor more often to check for HL. Your doctor will recommend what tests you should have and how often you should have them. […] Learn how cancer can be prevented and what you can do to reduce your risk.

• #155 Antimicrobial Prophylaxis in Lymphoma by Chemotherapy Regimen

  https://www.scientificarchives.com/article/antimicrobial-prophylaxis-in-lymphoma-by-chemotherapy-regimen

  General prophylaxis indications and duration of antimicrobial therapy can be referenced in Table 3. Assuming no definite contraindications, the preferred first-line antimicrobial prophylactic agents are: levofloxacin 500 mg or 750 mg daily for anti-bacterial prophylaxis, acyclovir 400 mg twice daily for anti-viral prophylaxis, fluconazole 400 mg daily for anti-fungal prophylaxis, and trimethoprim-sulfamethoxazole (TMP-SMX) 1 double strength (800 mg/160 mg) tablet three times weekly for PJP prophylaxis. […] Given the complexity in determining the appropriate antimicrobial prophylaxis in lymphoma based on the specific chemotherapy regimen, classifying prophylaxis indications based on treatment regimens will assist in guiding clinicians when treating lymphoma. Conversely, understanding indications for prophylaxis is imperative to preventing unnecessary prescribing of antimicrobial prophylaxis. This knowledge will limit medication adverse effects, prevent antibiotic resistance, and reduce avoidable costs.

• #156 Lymphoma and Infection: Do I Need to Take Medication to Prevent Infection? – New Developments in Lymphoma

  https://cornell-lymphoma.com/2013/04/30/lymphoma-and-infection-do-i-need-to-take-medication-to-prevent-infection/

  In some instances, patients may be started on medicines to prevent or minimize infection. […] Prophylaxis is recommended for intermediate or high-risk patients, including patients that are expected to have neutropenia. […] The use of levofloxacin prophylaxis is only recommended for patients with neutropenia that lasts longer than 7 days. […] ASCO guidelines recommend considering prophylaxis only for patients with profoundly low white blood cell counts (ANC 100) longer than 7 days. […] Antiviral medications may be recommended. […] You may require preventative medication, typically with TMP-SMX, if you are on steroids for a prolonged period of time (1 month), or are receiving treatment with alemtuzumab or purine analogs (i.e., fludarabine). […] ASCO 2012 guidelines recommended all patients who are receiving cancer treatment to receive the seasonal flu vaccine, along with their family and household contacts. […] Guidelines from the Centers for Disease Control (CDC) include administration of a pneumococcal vaccine in all patients with lymphoma.

• #157 Prophylaxis and Management of Secondary CNS Lymphoma

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9529879/

  Nevertheless, given the poor prognosis of patients with CNS relapse and the limitations of the data, we continue to use IT chemotherapy prophylaxis for our patients with high-risk of CNS spread including those with 2 sites of extranodal involvement and concomitantly elevated LDH, MYC rearrangement, bone marrow involvement by large cell lymphoma, and HIV positivity.

• #158

  https://haematologica.org/article/view/7964

  The authors recommend screening patients for CNS involvement by lumbar puncture and cerebrospinal fluid (CSF) analysis by conventional cytology (CC) and FCM in order to provide prophylaxis in the following situations: Increased serum LDH and involvement of 1 extranodal site (recommendation 1, level of evidence B), Extranodal involvement of testis (recommendation 1, level of evidence B) or breast (recommendation 2, level of evidence B), Extranodal involvement of kidney, adrenal gland (recommendation 2, level of evidence C) or epidural space (recommendation 2, level of evidence D), High risk CNS-IPI (recommendation 2, level of evidence B), MYC rearrangements associated to BCL2 or BCL6 rearrangements (recommendation 2, level of evidence C). […] CNS-directed prophylaxis should be offered to patients at high-risk of CNS relapse (recommendation 1, level of evidence B). IV MTX is recommended as CNS prophylaxis in high-risk patients (recommendation 2, level of evidence B). IV MTX as CNS prophylaxis should be administered during primary therapy at a dose of 3 g/m2, alternating with immunochemotherapy (recommendation 1, level of evidence B), and should be given according to published treatment schemes and in the context of performance status and renal function. Delay of subsequent cycles of systemic immunochemotherapy should be avoided (recommendation 1, level of evidence B). […] Patients with primary testicular lymphoma should receive IT MTX during primary chemotherapy (recommendation 1, level of evidence B).

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