Materiały źródłowe

• #1 Varicose Veins: Diagnosis and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2019/0601/p682.html

  Varicose veins are twisted, dilated veins most commonly located on the lower extremities. The exact pathophysiology is debated, but it involves a genetic predisposition, incompetent valves, weakened vascular walls, and increased intravenous pressure. […] Venous disease resulting in valvular reflux appears to be the underlying cause of varicose veins. The exact pathophysiology is debated, but it involves a genetic predisposition, incompetent valves, weakened vascular walls, and increased intravenous pressure. In most cases, the valvular dysfunction is presumed to be caused by a loss of elasticity in the vein wall, with failure of the valve leaflets to fit together. […] Established risk factors for varicose veins include family history of venous disease; female sex; older age; chronically increased intra-abdominal pressure due to obesity, pregnancy, chronic constipation, or a tumor; prolonged standing; deep venous thrombosis causing damage to valves and secondary revascularization; and arteriovenous shunting.

• #2 Varicose Veins – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK470194/

  Varicose veins are characterized by subcutaneous dilated, tortuous veins greater than or equal to three millimeters, involving the saphenous veins, saphenous tributaries, or non-saphenous superficial leg veins with age and family history considered important risk factors. […] The risk factors for varicose veins include female sex, multiparity, body weight, constipation, and history of venous thrombosis. […] Prolonged standing or walking at work has been suggested to be a cause of VVs. […] Despite the multifactorial pathogenesis of varicose veins, the contributing genetic and environmental factors are understudied. […] Interestingly, height has emerged as a new potential risk factor, and several mendelian randomization analyses examined height’s causal role in varicose vein development and severity.

• #2 Varicose Veins – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK470194/

  Recent mendelian randomization studies unveiled the positive and inverse association of genetically-predicted factors. […] However, circulating minerals, including calcium and zinc levels, showed an inverse association with varicose veins development. […] More than 850 new SNPs associated with varicose veins were evaluated, and 30 independent putative genetic variants were assessed. […] A limited number of genetic disorders have been correlated with varicose veins disease.

• #3 Varicose veins – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/varicose-veins/symptoms-causes/syc-20350643

  Veins return blood from the rest of the body to the heart. To return blood to the heart, the veins in the legs must work against gravity. Weakened valves, also called incompetent valves, within the veins might cause varicose veins. The weakened valves let blood pool in the veins instead of traveling to the heart. When blood pools in the veins, the veins become larger, making them show under the skin. […] Weak or damaged valves can lead to varicose veins. […] Tiny valves in the veins open as blood flows toward the heart, then close to stop blood from flowing backward. If these valves are weak or damaged, blood can flow backward and pool in the veins, causing the veins to stretch or twist.

• #4 Varicose Veins – Varicose Veins | NHLBI, NIH

  https://www.nhlbi.nih.gov/health/varicose-veins

  Varicose veins are a common condition caused by weak or damaged vein walls and valves. Veins have one-way valves inside them that open and close to keep blood flowing toward the heart. Weak or damaged valves or walls in the veins can cause blood to pool and even flow backward. This is called reflux. The veins may grow larger and become distorted, resulting in varicose veins. […] Varicose veins may form whenever blood pressure increases inside your veins. This can happen because of age, pregnancy, overweight and obesity, repeated sitting or standing for long periods, or an inactive lifestyle. Your risk may be higher if you have a family history of varicose veins.

• #5

  https://www2.hse.ie/conditions/varicose-veins/causes/

  Varicose veins are usually caused by weak vein walls and valves. […] Sometimes the walls of the veins become stretched and lose their elasticity. This causes the valves to weaken. […] We don’t know why the walls of the veins stretch and the valves in your veins weaken. Some people develop the condition for no clear reason. […] Women are more likely to get varicose veins than men. This may be because female hormones tend to relax the walls of veins. This makes the valves more prone to leaking. […] Your risk of developing varicose veins is higher if a close family member has the condition. Varicose veins may be inherited. They may be partly caused by your genes. […] As you get older, your veins start to lose their elasticity. The valves inside them stop working as well. […] Being overweight puts extra pressure on your veins which means they have to work harder to send the blood back to your heart. This can put increased pressure on the valves and makes them more prone to leaking.

• #6

  https://www.beaumont.org/conditions/varicose-veins

  Varicose veins are caused by increased blood pressure inside the superficial leg veins. […] When the one-way valves become weakened or damaged, blood can collect in the veins, causing them to become enlarged. […] Sitting or standing for long periods can cause blood to pool in the leg veins, increasing the pressure within the veins. […] In persons who are prone to varicose veins, the veins can stretch as a result of increased pressure. […] This stretching of the veins may weaken the walls of the veins and damage the valves. […] Although these factors increase a person’s risk, they do not necessarily cause the disease.

• #7 10 Things That May be Contributing to Your Varicose Veins

  https://www.metroveincenters.com/blog/10-things-that-may-be-contributing-to-your-varicose-veins

  This strain, aided with the heavy hand of gravity, can damage the stability of your veins. […] Although avoiding vein disease simply may not be in the cards for those with genetic predispositions, good lifestyle choices can help stave off symptoms and keep them milder for longer, delaying the worsening of varicose veins. […] Vein disease is progressive, which means it will worsen over time if left untreated. Vein disease does not go away on its own and can lead to more severe symptoms such as venous ulcers and wounds on your legs if not addressed.

• #7 10 Things That May be Contributing to Your Varicose Veins

  https://www.metroveincenters.com/blog/10-things-that-may-be-contributing-to-your-varicose-veins

  Vein disease is a progressive condition that 1 in 3 adults experience at some point in their lives. […] Regardless of how healthy someone is overall, genetic predispositions and lifestyle choices can affect the onset and progression of chronic venous insufficiency, which includes varicose veins and other uncomfortable symptoms. […] Absolute prevention is not scientifically possible because of factors like autoimmune disease, sex/gender, pregnancy, and age, which are entirely outside our control. However, there certainly are controllable factors which can accelerate or worsen vein disease. […] Women are more likely than men to develop vein disease. […] People over the age of 45, and especially those over 60, experience symptoms of vein disease at a higher scale than people in their 30s — though it is not impossible to experience vein disease before the age of 45.

• #7 10 Things That May be Contributing to Your Varicose Veins

  https://www.metroveincenters.com/blog/10-things-that-may-be-contributing-to-your-varicose-veins

  If your family members have signs or symptoms of vein disease, you are significantly more likely to develop varicose veins. Additionally, certain conditions genetically predispose you to vein disease, such as diabetes and celiac disease. These can all affect your circulation and increase your chances of developing varicose veins. […] A higher volume of blood in the body plus the excess strain of gravity on your lower legs due to a growing belly puts pressure on your veins and can lead to the development of varicose veins during pregnancy and postpartum. […] Smoking causes vasoconstriction, or a tightening/narrowing of the veins. When veins are constricted, it is difficult for blood to move through uninhibited. Bulging veins and broken or leaky vein valves (which control blood’s one-way route) can be a result of constricted veins.

• #7 10 Things That May be Contributing to Your Varicose Veins

  https://www.metroveincenters.com/blog/10-things-that-may-be-contributing-to-your-varicose-veins

  Caffeine can temporarily constrict blood vessels and mildly elevate blood pressure. While this effect is generally short-term, prolonged high caffeine consumption may strain vein valves, especially in those already at risk for vein problems. […] Alcohol is a vasodilator, the opposite of a vasoconstrictor. Vasodilation abnormally expands the veins and allows more blood to flow. If you consume alcohol on a daily basis, or consume large amounts of alcohol regularly, this can be too much for your veins to bear. This can lead to malfunctioning valves and blood pooling in the veins. […] High levels of stress impact your entire body, brain to vein, and can cause vasoconstriction of your veins. […] Spending long periods of time sitting in the sky (plus the pressure changes within aircraft cabins) reduces blood flow. Lack of movement for extended periods of time, which we’ll discuss further in our next point, can put excess stress on the veins.

• #8 Varicose Veins: Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/4722-varicose-veins

  Varicose veins occur when the walls of your veins weaken. As blood pressure in your vein increases, the weakened walls allow your vein to get bigger. As your vein stretches, the valves that keep blood moving in one direction in your vein cant work as they should. The sluggish blood backs up or pools in your vein, causing your vein to swell, bulge and twist. […] Vein walls and valves can become weak for several reasons, including: Normal aging. Standing for prolonged periods of time. Hormones. Excess weight. […] Certain factors increase your chances of developing a varicose vein, including: Age: Because of the aging process, vein walls and valves dont work as well as they once did. Veins lose elasticity and stiffen. Hormones: Female hormones can allow the walls of the veins to stretch. Women who are pregnant, taking the birth control pill or going through menopause have a higher risk of varicose veins because of changes in hormone levels. Family history: You can inherit this condition if it runs in your family. Lifestyle: Standing or sitting for long periods decreases circulation. Overall health: Certain health conditions can increase pressure in your veins. Tobacco use: People who use tobacco products are more likely to develop varicose veins. Weight: Excess weight puts pressure on blood vessels.

• #9 Varicose Veins | UCSF Department of Surgery

  https://surgicaloncology.ucsf.edu/condition/varicose-veins

  Weak or damaged valves in the veins can cause varicose veins. […] If the valves are weak or damaged, blood can back up and pool in your veins. This causes the veins to swell. […] Weak valves may be due to weak vein walls. […] You may be at higher risk for weak vein walls due to increasing age or a family history of varicose veins. […] A number of factors may increase your risk for varicose veins, including family history, age, gender, pregnancy, overweight or obesity, and lack of movement. […] Having family members who have varicose veins may raise your risk for the condition. […] Getting older may put you at higher risk for varicose veins. […] Women tend to get varicose veins more often than men. […] During pregnancy, the growing fetus puts pressure on the veins in the legs. […] Being overweight or obese can put extra pressure on your veins. […] Standing or sitting for a long time, especially with your legs bent or crossed, may raise your risk for varicose veins.

• #10 What Causes Varicose Veins? | The Vein Institute

  https://www.theveininstitute.com.au/varicose-veins-causes/

  Varicose veins can be a hassle, both in appearance and discomfort. And unfortunately, some people are more likely to develop them than others. From genetics to lifestyle factors, here are the common risk factors and causes of varicose veins. […] Genetics are believed to be the primary cause of varicose veins. There is strong evidence that weakness in your veins and valves is inherited. Your unique genetic profile determines the strength of your vein walls, valves and muscle density all of which provide support to your circulatory system. In addition to being born with weak veins, you can inherit too few valves from one or both of your parents. […] Excess weight is associated with health risks like high blood pressure, elevated cholesterol, and varicose veins. Having too much weight can strain your veins, increasing the likelihood of certain branches turning varicose.

• #11 What Factors Increase My Risk for Varicose Veins? – Empire Vein & Vascular Specialists

  https://empirevein.com/en/blog/vein-specialist/factors-that-increase-risk-for-varicose-veins/

  Varicose veins and spider veins affect 30 million U.S. adults at a cost of over $1 billion per year in direct healthcare expenses and currently, those numbers are increasing rapidly. There are numerous reasons why varicose veins occur, some of which you can modify while others cannot be changed. […] Your genes play a big part in whether you will develop varicose veins. To date, scientists have identified 30 genes that contribute to the risk for varicose veins, with the strongest association being a gene that regulates blood pressure. Overall, genetic alterations account for more than 60% of the difference in susceptibility to varicose veins from one person to the next. […] If both of your parents have varicose veins you have a 90% chance of developing varicose veins at some time in your life. If one of your parents is affected your risk is 25% if you are male and 62% if you are female. When neither parent is affected the risk for the child is 20%.

• #11 What Factors Increase My Risk for Varicose Veins? – Empire Vein & Vascular Specialists

  https://empirevein.com/en/blog/vein-specialist/factors-that-increase-risk-for-varicose-veins/

  Occupations that require prolonged standing are associated with significantly higher rates of varicose veins. Standing still increases pressure in the veins and decreases the pumping effects of calf muscles in assisting return blood flow and reducing the pooling of blood in the legs. […] As you age your risk for varicose and spider veins increases. In the general population around 30% of women and 15% of men are affected, but by the age of 70 prevalence increases to 77% in women and 57% in men. […] Women who use hormone replacement therapy may place themselves at greater risk since estrogen makes blood vessel walls more expandable leading to reflux of blood and distention of veins. […] Most studies find that women are more prone to varicose veins and spider veins than men. […] However, men tend to develop advanced stages of varicose veins at a higher rate than women and this is true even when age is factored out.

• #11 What Factors Increase My Risk for Varicose Veins? – Empire Vein & Vascular Specialists

  https://empirevein.com/en/blog/vein-specialist/factors-that-increase-risk-for-varicose-veins/

  Low-fiber diets, which are common in the U.S., lead to chronic constipation (having a bowel movement less frequently than once per day). Straining to evacuate increases pressure in the abdomen and when this happens on a regular basis, can lead to vein dilation. […] Having a body mass index (BMI) of more than 20 almost triples your risk for varicose veins. Increased abdominal pressure associated with obesity results in decreased return blood flow from the legs and, therefore, increased pressure in the veins. […] Women who have had two or more pregnancies have a 20% to 30% increased risk for developing varicose veins. […] If you were previously diagnosed with a blood clot in your leg, known as deep vein thrombosis, your risk for developing varicose and spider veins is significantly increased due to the increased pressure and stress on the veins from the occlusion of venous blood flow. […] The taller you are the more work your body has to do to push blood back to your heart from your lower body, making you more susceptible to problems such as blood pooling and reflux that can lead to varicose and spider veins.

• #12 Varicose Veins | The Foundation to Advance Vascular Cures

  https://www.vascularcures.org/varicose-veins

  Varicose veins are enlarged, bulging superficial veins that can be felt beneath the skin, generally larger than 3-mm in diameter. […] Varicose veins are usually located on the inside of the calf or thigh and develop due to weakness of the vein wall and loss of valve function. […] The causes of varicose veins may be primary, secondary, or congenital. Primary varicose veins develop as a result of an inherent weakness in the wall of the vein. Varicose veins can have a hereditary factor and often occur in several members of the same family. Varicose veins that develop after trauma or deep vein thrombosis are of secondary cause. Congenital varicose veins are due to disorders in the natural development of the venous system, and usually are part of a vascular malformation in the limb, present at birth.

• #13 Varicose veins: Causes, symptoms, treatment

  https://www.medicalnewstoday.com/articles/240129

  Varicose veins are a common health issue that develops when atypical or damaged valves in the veins allow blood to flow in the wrong direction or to pool. […] Certain lifestyle factors or health conditions may increase the risk of varicose veins. […] According to a 2019 article, the following factors may increase the risk of varicose veins: a family history of varicose veins, being female, older age, pressure on the abdomen, which may be due to overweight or obesity, pregnancy, tumors, chronic constipation, and prolonged sitting or standing. […] A 2015 article also highlights that changes in hormone levels can lead to blood vessel wall relaxation. […] Varicose veins occur when blood pools in the veins as it tries to return to the heart to pick up fresh oxygen.

• #14 Varicose Veins: Causes, Symptoms & Treatment in Houston

  https://www.premiervein.com/blog/what-causes-varicose-veins/

  Varicose veins are common, affecting about 23 percent of adults in the U.S., impacting women twice as often as men. Varicose veins are twisted, enlarged veins. Their gnarled appearance is the result of blood pooling inside the veins that are weak or damaged. In veins with weak or damaged valves, this isn’t done effectively, and the blood can flow backward, which is what creates the pooling in the veins that causes them to stretch and twist. […] Your gender plays a role, as women are more likely than men to develop this condition. Hormonal fluctuation can be a factor, because the shifts in hormones before a menstrual period, during pregnancy, or in menopause can relax vein walls. […] Age is also a factor. As we get older there is natural wear and tear on the valves in our veins. Sometimes, that erosion can impede the valves function, allowing blood to flow backward and collect in the veins.

• #15 Vericose Vein Basics and Causes

  https://www.webmd.com/skin-problems-and-treatments/understanding-varicose-veins-basics

  During pregnancy, the volume of blood in your body increases to support the growing baby. This can enlarge the veins in the legs. […] The uterus puts pressure on your veins during pregnancy, which can also lead to varicose veins, sometimes around the vagina and buttocks. […] The changes in hormones during pregnancy also may relax the vein walls, contributing to varicose veins. […] Certain things — some of which you can control and some of which you cant — increase the chances that youll get varicose veins. They include: Pregnancy. Varicose veins usually improve 3 months to a year after delivery. Family history. You are more likely to have varicose veins if they run in your family. Obesity. Being overweight puts extra pressure on your veins. Older age. Valves in the veins weaken because of wear and tear as you age. Your veins start to lose elasticity, so vein walls and valves dont work as well. Your sex. Women are four times more likely than men to get varicose veins.

• #15 Vericose Vein Basics and Causes

  https://www.webmd.com/skin-problems-and-treatments/understanding-varicose-veins-basics

  Varicose veins are a relatively common condition. For many people, they are a family trait. Women are at least twice as likely as men to develop them. In the U.S. alone, they affect up to 35% of people. […] Any condition that puts too much pressure on the legs or abdomen can lead to varicose veins. The most common things that bring about pressure are pregnancy, obesity, and standing for long periods of time. Chronic constipation and — in rare cases, tumors — also can cause varicose veins. Not being active also may lead to varicosity because muscles that are out of condition offer poor blood-pumping action. […] The odds of getting varicose veins also increase with age, as veins weaken when you get older. A previous leg injury may damage the valves in a vein, resulting in becoming varicose. Your family history also plays a role, so if other family members have varicose veins, there is a greater chance you will, too.

• #15 Vericose Vein Basics and Causes

  https://www.webmd.com/skin-problems-and-treatments/understanding-varicose-veins-basics

  Prolonged standing or sitting. Standing or sitting for long periods decreases circulation. […] Varicose veins may not be cause for concern if they’re only cosmetic. But if they are serious and go untreated, they may get worse. Without treatment, they may cause ulcers, bleeding, and skin discoloration. […] Sometimes, varicose veins can develop into more serious conditions, such as chronic venous insufficiency, which means the veins in your legs are damaged and dont work properly. […] Complications of varicose veins are rare, but they can be serious. They include: Ulcers. On the skin near varicose veins, ulcers (open sores) can form, and they can be painful. […] Blood clots. If you have varicose veins, you may be more likely to develop blood clots, including a type called DVT, which is a blood clot deep inside the body. […] Chronic venous insufficiency. Severe varicose veins may be a sign of this condition, which means your veins are unable to pump blood to your heart the way they should.

• #16 Varicose veins

  https://dermnetnz.org/topics/varicose-veins

  Approximately one-third of men and women aged 1864 years have varicose veins. They are more common in women and those with a family history of venous disease. […] In normal leg veins, one-way valves direct the flow of venous blood from superficial venules to larger superficial veins, then to the deep veins, and eventually to the heart. Muscle contractions create a pumping action to help the flow of blood to the heart (known as the venous return). In the legs, varicose veins are a manifestation of venous insufficiency. […] Risk factors for varicose veins include: Obesity obesity increases venous reflux and venous pressure as a result of raised intra-abdominal pressure; Age varicose veins become increasingly common with age; Pregnancy the enlarged uterus causes increased intra-abdominal pressure and direct pressure on the iliac veins; hormonal changes also cause the valves and vessels to become more malleable during pregnancy; Prolonged standing sustained pressure over time may cause venous distension and valve failure; A family history primary valvular failure is hereditary, and varicose veins may affect both identical twins in 75% of cases.

• #17 Varicose veins and spider veins | Better Health Channel

  https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/varicose-veins-and-spider-veins

  Varicose veins are caused by faulty valves within veins, that allow blood to pool. […] We do not know the causes of varicose veins and spider veins. However, in many cases, they run in families. Women seem to get the problem more often than men. Changes in oestrogen levels in a womans blood may have a role in the development of varicose veins. Such hormonal changes occur during puberty, pregnancy, breastfeeding and menopause. Other factors that may increase your risk of developing varicose veins include: standing or sitting for long periods, being immobile for long periods for example, being confined to bed, lack of exercise, obesity, smoking, older age, previous deep blood clots (deep vein thrombosis).

• #18 Varicose Viens and What Causes Them azura-logo-white

  https://www.azuravascularcare.com/infoveins/what-are-varicose-veins/

  Gender – It’s believed that female hormones relax your veins, increasing the risk for varicose veins. The risk may also be increased with the use of female hormone medications such as birth control pills and hormone replacement therapy. […] Vein damage – Damage to the valves or walls of your veins, such as from a blood clot or injury, can increase your chance that the valves will weaken, resulting in varicose veins. […] Weight – Increased body weight can put extra pressure on your veins, making varicose veins more likely.

• #19 6 varicose vein myths debunked – Mayo Clinic Health System

  https://www.mayoclinichealthsystem.org/hometown-health/speaking-of-health/6-varicose-vein-myths-debunked

  Varicose veins are twisted, enlarged and bulging veins that most commonly affect your legs. Nobody wants to develop these blue or purple, and sometimes painful, veins. Unfortunately, about half of adults do at some point in their lives. […] Varicose veins form when internal valves break down and allow blood to flow in the wrong direction down the leg and pool within the veins. This causes the vein to stretch and dilate, leading to swelling, aching and pain. To make matters worse, veins often can bulge more and more to hold the increasing amount of blood, which results in even more persistent discomfort. […] It is true that the risk of varicose veins increases with age as aging causes wear and tear on the valves in your veins that regulate blood flow. […] During pregnancy, the volume of blood in your body increases. While this change supports the growing fetus, it also can produce an unfortunate side effect: enlarged veins in your legs. Hormonal changes during pregnancy also may play a role.

• #19 6 varicose vein myths debunked – Mayo Clinic Health System

  https://www.mayoclinichealthsystem.org/hometown-health/speaking-of-health/6-varicose-vein-myths-debunked

  Varicose veins are not simply a cosmetic issue. At best, they are a cosmetic concern with few symptoms. More commonly, they lead to painfully swollen, aching and tired legs that worsen with even a minimal amount of exercise or standing. At worst, they indicate a progressive disease process called chronic venous insufficiency, which causes poor wound healing, ulcers and, in the most severe cases, can lead to amputation. Your health care provider should evaluate all varicose veins, especially symptomatic ones.

• #20 What Makes Varicose Veins Worse? Causes, Symptoms & Prevention Tips

  https://cardiovascularcenter.com/patient-resources/blog/what-makes-varicose-veins-worse

  Excess body fat can lead to hormonal imbalances, particularly in estrogen levels. Elevated estrogen can contribute to the weakening of vein walls. […] Obesity is associated with chronic low-grade inflammation in the body, which can damage blood vessels and contribute to vein problems. […] Extended periods of standing or sitting can lead to varicose veins. This happens because blood pools in the leg veins, causing increased pressure, reduced muscle action, weakened valves, slowed circulation, fluid retention, and decreased vein elasticity. […] A person’s gender, age, and genetics can also be varicose veins risk factors and lead to the development of varicose veins, or lead to varicose veins getting worse. […] Women are 2-3 times more likely to develop varicose veins than men. […] The risk of developing varicose veins increases with age. […] Having a family member with varicose veins increases your risk by about 50%. […] Genetic factors can influence vein wall strength, valve function, and overall circulatory health.

• #21 Varicose Veins – Cardiovascular Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/cardiovascular-disorders/peripheral-venous-disorders/varicose-veins

  Varicose veins may result from primary venous valvular insufficiency with reflux or from primary dilation of the vein wall due to structural weakness. […] In some people, varicose veins result from chronic venous insufficiency and venous hypertension. […] Most people have no obvious risk factors. Varicose veins are common within families, suggesting a genetic component. Varicose veins are more common among women because estrogen affects venous structure, pregnancy increases pelvic and leg venous pressures, or both. […] Rarely, varicose veins are part of Klippel-Trnaunay-Weber syndrome, which includes congenital arteriovenous fistulas and diffuse cutaneous capillary angiomas.

• #22 Causes of Varicose Veins in Adults – Minneapolis Vein Center

  https://www.mplsvein.com/blog/causes-of-varicose-veins-in-adults/

  Varicose veins, also called varicoses or varicosities, happen when your veins become enlarged, dilated, and overfilled with blood. Caused by weakened valves, varicose veins develop when your veins lose their elasticity and when they stretch or become otherwise enlarged. This causes the valves to leak inside, allowing blood to flow backward towards the feet. Other causes of varicose veins include: Pregnancy […] Menopause […] Advanced age (50+) […] Standing for long periods of time […] Obesity […] Family history of varicose veins. In rare cases, varicose veins may develop as a result of a tumor in the pelvis or clots in the deep veins of the legs, called deep vein thrombosis. Your chances of developing varicose veins increase if you’re: On your feet all day – particularly if you are standing a lot rather than walking around

• #22 Causes of Varicose Veins in Adults – Minneapolis Vein Center

  https://www.mplsvein.com/blog/causes-of-varicose-veins-in-adults/

  Have a sedentary lifestyle – exercise helps to pump blood up from the legs […] Pregnant – there are a number of reasons for this. The change in hormones during pregnancy causes all tissues in the body to relax, and this also happens in veins. […] Overweight – being overweight is associated with varicose veins, particularly in women, although the exact reason for this is not yet fully understood […] Suffer long-standing constipation – constipation has a similar effect on the pelvic region as pregnancy – blood flow from the legs is partially obstructed. […] A full bladder – some people are not able to empty their bladders completely. One likely cause of this in men over the age of 50 is an enlarged prostate. Although many factors are known to contribute to the development of varicose veins, they can also appear without any clear reason or trigger.

• #23 Could Your Job Be a Cause of Varicose Veins? | Charlotte RadiologyLinkedInTwitterInstagramFacebookYouTube

  https://www.charlotteradiology.com/blog/varicose-veins-causes/

  Varicose veins are common as you age, especially if you’re a woman. But your age isn’t the only factor that puts you at risk of developing varicose veins. Certain jobs can increase the risk of unsightly veins in your legs. Professions that require you to stand for most of the day, such as nursing or factory work, are one cause of varicose veins. And jobs where you sit all day, such as office workers, can also lead to varicose veins. […] Varicose veins are extremely common, affecting at least 20% of people during their lifetime. However, women have a greater likelihood of developing varicose veins. The main causes of varicose veins include: […] Working a job where you sit or stand for long periods of time. […] If you have a job where you spend most of the day sitting or standing for long periods of time, you have a higher risk of developing varicose veins.

• #24 Causes and Symptoms of Varicose and Spider Veins

  https://www.cvvcenters.com/blog/what-are-the-causes-symptoms-of-varicose-spider-veins/

  Varicose veins are most common on the legs. […] When these one-way valves work properly, they keep blood moving toward the heart rather than traveling backwards and pooling at the base of the leg due to gravity. If one of these valves becomes damaged, blood can build up and place pressure on the vein. Over time, this damages the vein and causes it to swell. […] Some factors that contribute to varicose veins or increase the risk of developing them include: Genetics If your mom or dad have varicose veins, your risk is higher, Being overweight or obese, Hormonal changes related to pregnancy, menopause, postmenopausal hormone therapy, or birth control pills, Standing or sitting for long periods of time, Wearing constrictive garments like girdles, A previous history of a blood clot, Prior vein surgery, Smoking, Being over the age of 50.

• #24 Causes and Symptoms of Varicose and Spider Veins

  https://www.cvvcenters.com/blog/what-are-the-causes-symptoms-of-varicose-spider-veins/

  These factors have something in common they place extra pressure on the valves or damage the vein in some way. […] Some of the same factors that increase the risk for varicose veins also place you at risk for spider veins, especially genetics, hormonal changes, and obesity. […] Varicose veins may be asymptomatic but they can also cause a variety of symptoms. […] However, you can also experience more serious symptoms when you have varicose veins. For example, you can develop a blood clot inside a damaged vein. Another possible, but rare, complication is the formation of a skin ulcer in the area where a vein is damaged. Untreated varicose veins can also lead to skin problems, including skin discoloration. […] Varicose veins are often a progressive problem unless you correct them.

• #25 Varicose Veins – What causes them and how to treat them | JOBST USA

  https://www.jobst-usa.com/living-with-your-condition/diagnoses/types-of-venous-conditions/varicose-veins

  Varicose veins are usually caused by damaged vein walls and valves. […] The following risk factors can impact the likelihood of developing varicose veins: Family history, Personal medical history of blood clots, Obesity, Gender (women are more likely to develop the condition than men), Older age, Long periods of standing or sitting, Hormonal changes, e.g. pregnancy, birth control medication, or hormone replacement therapy. […] Many women notice varicose veins during pregnancy. Besides a pooling of blood in the legs and an increase of the blood volume in general, hormones can further weaken the vein walls during pregnancy.

• #26 Varicose Veins – Symptoms, Causes, Complications and Treatment PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact Nu

  https://www.pacehospital.com/varicose-veins-symptoms-causes-complications-and-treatment

  Pregnancy: Changes during the pregnancy can increase the risk of varicose veins. The weight of the growing baby puts pressure on the large blood vessels in the pelvis, altering blood flow and the raised blood volume can also enlarge the veins making pumping of blood back to the heart inefficient. […] Prolonged exposure to sunlight: Excessive sun exposure can break down the collagen in your skin and weaken your blood vessels, resulting in varicose veins. […] Ageing: Most people who develop varicose veins are between 40 and 80. […] Medicines: Taking prolonged hormonal replacement therapy or oral contraceptive usage may also increase the risk of varicose veins. […] Family history: If there is a family history of varicose veins, then the possibility of developing varicose veins will be very high.

• #27 Varicose Veins Causes | Stanford Health Care

  https://stanfordhealthcare.org/medical-conditions/blood-heart-circulation/varicose-veins/causes.html

  Varicose veins are caused by weakened valves and veins in your legs. Normally, one-way valves in your veins keep blood flowing from your legs up toward your heart. When these valves don’t work as they should, blood collects in your legs, and pressure builds up. The veins become weak, large, and twisted. […] Varicose veins often run in families. You may be born with defective valves or weak walls in your veins, or you may develop them later in life. […] Varicose veins are more common in women than in men. And they happen more often as people get older. […] Varicose veins often form during pregnancy. They might become less prominent after pregnancy and may disappear completely.

• #28 Chronic Venous Insufficiency: Causes, Symptoms and Treatment

  https://my.clevelandclinic.org/health/diseases/16872-chronic-venous-insufficiency-cvi

  Chronic venous insufficiency happens when your leg veins become damaged and cant work as they should. […] Chronic venous insufficiency (CVI) is a form of venous disease that occurs when veins in your legs are damaged. […] CVI can happen due to damage in any of your leg veins. […] Chronic venous insufficiency causes many symptoms in your legs and feet. […] Chronic venous insufficiency happens when the valves in your leg veins dont work properly. […] Causes of valve malfunction may be congenital, primary or secondary. […] Deep vein thrombosis (DVT) is the most common cause of chronic venous insufficiency.

• #29 Varicose veins – Wikipedia

  https://en.wikipedia.org/wiki/Varicose_veins

  Varicose veins have no specific cause. Risk factors include obesity, lack of exercise, leg trauma, and family history of the condition. […] They also develop more commonly during pregnancy. […] Occasionally they result from chronic venous insufficiency. […] Underlying causes include weak or damaged valves in the veins. […] Varicose veins are more common in women than in men and are linked with heredity. […] Other related factors are pregnancy, obesity, menopause, aging, prolonged standing, leg injury and abdominal straining. […] Venous reflux is a significant cause. […] Research has also shown the importance of pelvic vein reflux (PVR) in the development of varicose veins. […] Varicose veins in the legs could be due to ovarian vein reflux. […] Both ovarian and internal iliac vein reflux causes leg varicose veins.

• #29 Varicose veins – Wikipedia

  https://en.wikipedia.org/wiki/Varicose_veins

  In addition, evidence suggests that failing to look for and treat pelvic vein reflux can be a cause of recurrent varicose veins. […] There is increasing evidence for the role of incompetent perforator veins (or „perforators”) in the formation of varicose veins. […] Varicose veins could also be caused by hyperhomocysteinemia in the body, which can degrade and inhibit the formation of the three main structural components of the artery: collagen, elastin and the proteoglycans. […] Another cause is chronic alcohol consumption due to the vasodilatation side effect in relation to gravity and blood viscosity.

• #30 Varicose Veins (Venous Insufficiency) – Evaluation and Treatment

  https://www.radiologyinfo.org/en/info/varicose-veins

  Varicose veins (venous insufficiency) is a condition in which veins are not able to pump blood back to the heart. This causes blood to pool in the blood vessels so that they become enlarged or varicose over time. […] Venous insufficiency is a medical condition in which veins in the body (most often in the legs) are not able to pump blood back to the heart. This causes blood to pool in the blood vessels so that they become enlarged (varicose) or dilated over time. […] If the muscles and one-way valves become weak or fail, the vein becomes incompetent and blood begins to collect in the vein rather than returning to the heart. […] Risk factors for venous insufficiency include: family history, pregnancy and other conditions that put pressure on veins in the legs, a history of blood clots, a history of smoking, standing or sitting for long periods of time, being overweight, which increases pressure on the legs, menopause, aging, which results in decreased elasticity of blood vessels, weakened blood vessel walls, inflammation of the veins (known as phlebitis), chronic constipation and in rare cases, tumors.

• #31 What Problems Can My Varicose Veins Cause?: Woodlands Heart and Vascular Institute: Cardiologists

  https://www.woodlandsheartinstitute.com/blog/what-problems-can-my-varicose-veins-cause

  Varicose veins begin when one-way valves inside the veins become damaged and dysfunctional. […] CVI is the underlying disease responsible for varicose veins. Varicose veins develop as the refluxing blood accumulates and engorges the vein. […] High venous pressure also causes health complications in your lower leg. […] If you dont seek treatment for varicose veins, CVI may cause one or more of the following conditions: […] As venous insufficiency slows circulation, your blood thickens, raising your risk for DVT. […] High venous pressure forces fluids out of the blood vessels in your lower leg. […] Hyperpigmentation is reddish-brown skin discoloration. […] The skin in your lower leg may thicken and harden, taking on a leathery texture. […] A venous stasis ulcer is a serious skin complication. The ulcer (a shallow, open wound) begins when fluids leaking from your veins break down the nearby skin.

• #32 Varicose Veins and Spider Veins: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1085530-overview

  Intrinsic pathological conditions and extrinsic environmental factors combine to produce a wide spectrum of varicose disease. […] Most varicose disease is due to elevated superficial venous pressures, but some people have an inborn weakness of vein walls and can develop varicosities even in the absence of elevated venous pressures. […] Heredity is important in determining susceptibility to primary valvular failure, but the specific genetic factors responsible for varicosities have not yet been elucidated. […] Prolonged standing leads to increased hydrostatic pressures that can cause chronic venous distention and secondary valvular incompetence anywhere within the superficial venous system. […] Pregnancy is a common cause of varicosities. […] Age is an independent risk factor for varicosities. […] Wherever a venous outflow obstruction exists, varicose veins may arise as a bypass pathway.

• #33 Causes of Varicose Veins and Other Vein Disorders | American Geriatrics Society | HealthInAging.org

  https://www.healthinaging.org/a-z-topic/varicose-veins-and-other-vein-disorders/causes

  Varicose veins may happen whenever blood pressure increases inside your veins. Among the reasons this increase can happen are being overweight, pregnant, or constipated. […] Varicose veins are more common in older adults, because of the lifetime of wear and tear on the valves. […] The tendency toward having varicose veins can be inherited. […] Womens blood vessels are designed to be flexible, which makes it easier for varicose veins to develop. […] Extra body weight puts more pressure on the veins. […] People who worked in jobs that required extended periods of standing or sitting are at greater risk. […] Chronic lung disease, which can increase the pooling of blood in the lower body. […] Dehydration, which occurs when the body doesn’t have enough liquids.

• #34 Stress and Other Surprising Factors That Cause Varicose Veins

  https://www.bassveincenter.com/blogs/stress-and-other-surprising-factors-that-cause-varicose-veins

  Varicose veins can develop for many reasons, from physical strain and stress to genetic inheritance, and everything in between. […] Stress puts strain on our minds and bodies, so stress management is key in your fight to prevent vein damage. […] Other bad habits, such as smoking, can increase your chances of developing cosmetic, even painful, varicose veins. […] This is due to the various changes women go through during puberty, pregnancy, and menopause. […] While this helps support the growing baby, the strain of this volume can enlarge veins in the legs. […] This, coupled with hormonal changes during pregnancy, can contribute to varicose veins. […] When humans age, the veins will naturally begin to weaken and can damage easily. […] Family history and a vigorous work environment, coupled with age, may progress the development of varicose veins under the skin.

• #35 What Causes Varicose Veins to Burst? Should You Call a Doctor?

  https://cacvi.org/what-causes-varicose-veins-to-burst/

  When varicose veins burst, they can cause significant bleeding, especially if the skin’s surface is breached. […] Significant blood loss is just one of the severe complications that can arise from varicose veins, often resulting in hypovolemic shock. […] Furthermore, if varicose veins are left untreated, they can lead to infection and septicemia. […] Another complication that can arise is ulceration. […] Varicose veins can also increase the risk of developing blood clots in the deeper veins, known as deep vein thrombosis (DVT). […] Additionally, varicose veins when left untreated can lead to prolonged issues with blood flow which can cause permanent changes in the skin’s texture and color. […] If a varicose vein bursts, it’s important to take immediate action to manage the situation and prevent further complications.

• #35 What Causes Varicose Veins to Burst? Should You Call a Doctor?

  https://cacvi.org/what-causes-varicose-veins-to-burst/

  Preventing varicose veins from bursting involves making certain lifestyle changes and adopting healthy habits. […] It also helps to maintain a healthy diet. […] Regular check-ups with a healthcare provider, particularly a vein specialist, can help monitor the condition of your veins and catch any issues early. […] Varicose veins can lead to significant health issues, including the risk of varicose veins bursting. […] Yes, the rupture of varicose veins is considered an emergency situation. […] The symptoms of varicose veins, such as leg swelling, aching pain, and significant bleeding, should never be ignored, as untreated varicose veins can escalate to chronic venous insufficiency. […] Different treatment options, including sclerotherapy, endovenous ablation, and compression stockings, which are effective in managing this condition and preventing complications.

• #36 Understanding What Causes Veins to be Visible in Legsclosechevron-downtwitterfacebookbarslinkedinyoutube-playinstagram

  https://www.georgiaeva.com/vein-disease/varicose-veins/why-do-you-get-varicose-veins/

  Highly visible veins in the skin may be normal. However, vein diseases can cause visible veins. In many cases, the more advanced the disease, the more apparent the symptoms become. […] This increased visibility is because vein disease causes the veins to become weak and unable to circulate blood adequately. As a result, the veins become enlarged and more visible. In addition, vein disease can cause the veins to become twisted and inefficient. […] Venous insufficiency causes the vein valves to become weakened and unable to close properly. When the valves fail, proper forward flow is lost and gravity begins to pull blood backwards in the wrong direction back down into the legs. The pooling of blood forces the veins to become dilated, swollen and twisted, leading to the formation of varicose veins. Most patients eventually develop symptoms of venous insufficiency including leg heaviness, fatigue, swelling, aching, cramping, itching, and even skin discoloration. If venous insufficiency is left untreated, major complications can occur. […] If left untreated, venous disease can lead to serious health complications, such as chronic pain, ulcers, and even deep vein thrombosis. Early diagnosis and treatment are essential to preventing long-term harm. Regular evaluations by a doctor can help detect venous diseases early.

• #37 Understanding the Causes and Risk Factors of Varicose Veins: A Comprehensive Guide _ Vascular Surgery Group

  https://vasculargroup.com/understanding-the-causes-and-risk-factors-of-varicose-veins/

  Several lifestyle factors can increase the risk of varicose veins. These include prolonged standing or sitting, lack of exercise, obesity, and smoking. […] Chronic venous insufficiency occurs when the valves in the veins are damaged or weakened, leading to poor circulation and the development of varicose veins. […] Deep vein thrombosis is a blood clot that forms in the deep veins of the legs. DVT can obstruct blood flow and damage vein valves, increasing the risk of varicose veins. […] Varicose veins can be caused by various factors, including genetics, age, gender, pregnancy, obesity, and prolonged periods of standing or sitting. Weak or damaged vein walls and valves contribute to the development of varicose veins. […] Yes, genetics play a significant role in the development of varicose veins. If one or both parents have varicose veins, you are more likely to develop them yourself.

• #38 Causes of Varicose Veins & Leg Ulcers

  https://legsmatter.org/information-and-support/health-concerns/varicose-veins/

  If you have no problems with the blood supply to your legs, compression therapy can be a good way of reducing your symptoms of varicose veins and swelling. […] Some patients unfortunately do experience a recurrence of varicose veins after surgery and this is known as neorevascularisation. […] Failure to treat varicose veins could result in patient suffering and impact on quality of life leading to depression. […] The Circulation Foundation is the UKs only dedicated vascular charity. They fund and promote research into the causes, treatment and prevention of vascular disease.

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