Materiały źródłowe

• #1 Can Bile Duct Cancer Be Prevented? | Preventing Bile Duct Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/bile-duct-cancer/causes-risks-prevention/be-prevented.html

  There’s no known way to prevent most bile duct cancers in the US. However, there are things you can do that might help lower your risk. […] Getting to and staying at a healthy weight is one important way you might be able to reduce your risk of bile duct cancer, as well as many other types of cancer. […] The American Cancer Society recommends that people try to stay at a healthy weight, keep physically active, and follow a healthy eating pattern. This includes eating plenty of fruits, vegetables, and whole grains, and limiting or avoiding red and processed meats, sugary drinks, and highly processed foods. […] Other ways you might be able to reduce your risk of bile duct cancer include: […] Get vaccinated against the hepatitis B virus (HBV) to prevent infection with the virus and the cirrhosis it can cause.

• #1 Can Bile Duct Cancer Be Prevented? | Preventing Bile Duct Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/bile-duct-cancer/causes-risks-prevention/be-prevented.html

  Take precautions to avoid blood-borne or sexually transmitted infections like HBV, hepatitis C, and other viruses that can cause cirrhosis. […] Treat hepatitis infections (such as B and C) to help prevent cirrhosis. […] If you do drink, have no more than 1 drink per day for women or 2 drinks per day for men. […] Quit (or dont start) smoking. […] Protect yourself against exposure to certain chemicals. […] If you travel to parts of the world where liver flukes are common, drink only purified water and eat only foods that have been thoroughly cooked.

• #2

  https://winshipcancer.emory.edu/cancer-types-and-treatments/bile-duct-cancer/prevention.php

  Cholangiocarcinoma is relatively rare in the U.S. Still, its important to learn about bile duct cancer prevention so you can protect yourself. […] While researchers are still working to understand exactly what causes bile duct cancer and have yet to make specific recommendations regarding bile duct cancer prevention, they have identified some risk factors for the disease. […] While theres no reliable way to prevent cholangiocarcinoma, the following bile duct cancer prevention recommendations may help you reduce your risk for developing the disease: […] Get vaccinated against hepatitis B and take steps to prevent infection with hepatitis C […] Limit alcohol use […] Dont smoke […] Maintain a body mass index below 25 […] Be physically active every day […] Eat a diet rich in fruits and vegetables and limit red and processed meat.

• #3 Cholangiocarcinoma (bile duct cancer)

  https://www.mymlc.com/health-information/diseases-and-conditions/c/cholangiocarcinoma-bile-duct-cancer/?section=Coping%20and%20support

  To reduce your risk of cholangiocarcinoma, you can: […] Stop smoking. Smoking is linked to an increased risk of cholangiocarcinoma. If you smoke, stop. If you have tried quitting in the past and haven’t been successful, talk with your doctor about strategies to help you quit. […] Reduce your risk of liver disease. Chronic liver disease is associated with an increased risk of cholangiocarcinoma. Some causes of liver disease can’t be prevented, but others can. Do what you can to take care of your liver. […] For instance, to reduce your risk of liver inflammation (cirrhosis), drink alcohol in moderation, if you choose to drink. For healthy adults, that means up to one drink a day for women and up to two drinks a day for men. Maintain a healthy weight. When working with chemicals, follow the safety instructions.

• #4 Cholangiocarcinoma (Bile Duct Cancer)

  https://my.clevelandclinic.org/health/diseases/21524-cholangiocarcinoma

  Theres no way to prevent bile duct cancer, but you can reduce your risk by protecting your liver (and bile ducts) from inflammation. This includes: […] Protecting yourself from viruses such as hepatitis B, hepatitis C and HIV. […] Limiting the amount of alcoholic beverages you drink. […] Maintaining a healthy body weight. […] Quitting smoking.

• #4 Cholangiocarcinoma | Vejthani Hospital

  https://www.vejthani.com/diseases-conditions/cholangiocarcinoma/

  Quit Smoking. People who smoke have a statistically greater chance of developing cholangiocarcinoma. […] Reduce your risk of liver disease. Cholangiocarcinoma is associated with chronic liver disease, so its important to do what you can to protect the health of your liver. Only drinking in moderation will help reduce the risk of liver inflammation (cirrhosis). Reducing your food intake will also help maintain a healthy weight and therefore reduce stress on your liver. When youre working with chemicals, always follow the safety instructions to avoid any contact with your skin, as some common industrial chemicals can cause liver damage.

• #5 Bile duct cancer | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/cancer/cancer-types-in-adults/bile-duct-cancer-cholangiocarcinoma/

  There are no guaranteed ways to avoid getting bile duct cancer, although it is possible to reduce your chances of developing the condition. […] The 3 most effective steps to reduce your chances of developing bile duct cancer are: giving up smoking (if you smoke), drinking alcohol in moderation, minimising your exposure to the hepatitis B and hepatitis C viruses. […] Not smoking is the most effective way of preventing bile duct cancer, as well as other serious health conditions, such as stroke, heart attack and lung cancer. […] If you are a heavy drinker, reducing your alcohol intake will help prevent liver damage (cirrhosis). This may, in turn, reduce your risk of developing bile duct cancer. […] A vaccine is available that provides immunisation against hepatitis B. […] The liver fluke is a major cause of bile duct cancer in Asia. It is a parasite which, after infection, damages the tissue of the bile duct and in some cases triggers the onset of bile duct cancer.

• #6 Bile Duct Cancer Treatment in Delhi, India | Cholangiocarcinoma Symptoms & Causes

  https://www.blkmaxhospital.com/our-specialities/gastrointestinal-cancer/conditions-treatments/bile-duct-cancer

  Vaccinating against the hepatitis B virus (HBV) to avoid infection and the cirrhosis that this virus can cause […] Preventing cirrhosis by taking precautions to reduce blood-borne or sexually transmitted diseases such as HBV and other viruses (such as hepatitis C virus and HIV) […] Treating hepatitis B and C to help avoid cirrhosis […] Avoiding exposure to hazardous compounds such as asbestos, radon, and dioxin.

• #7 Bile Duct Cancer – Prevention

  https://ruesch.georgetown.edu/bileductcancerprevention/

  Avoiding risk factors and increasing protective factors may help prevent cancer. […] Chronic Hepatitis B and C infections are risk factors that may lead to liver cancer. […] The following protective factors may decrease the risk of liver cancer: Hepatitis B vaccine, Treatment for chronic hepatitis B infection, Reduced exposure to aflatoxin B1. […] Cancer prevention clinical trials are used to study ways to prevent cancer. […] New ways to prevent liver cancer are being studied in clinical trials.

• #8 Cholangiocarcinoma | Bile Duct Cancer, Asbestos Link

  https://mesothelioma.net/cholangiocarcinoma/

  Knowing more about the causes of cholangiocarcinoma can help people avoid risk factors that could lead to a cancer diagnosis. People are less likely to be exposed to asbestos today, but it is still a risk factor. […] It is important to avoid asbestos, especially in older homes, and rely on asbestos professionals to find and abate the material. […] Cholangiocarcinoma is a cancer that may be triggered by asbestos exposure; however, many people develop the disease without experiencing any known exposure. […] Regardless of the cause, it is important to seek a diagnosis and treatment as early as possible.

• #9 Cholangiocarcinoma: Symptoms, Causes, Types, Staging & Treatment PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact

  https://www.pacehospital.com/cholangiocarcinoma-bile-duct-cancer-symptoms-causes-types-staging-treatment

  While many risk factors like age and genetics can’t be controlled, you can lower your risk of bile duct cancer. Key steps include maintaining a healthy weight, staying physically active, eating a healthy diet, limiting alcohol, and not smoking. Taking precautions to avoid hepatitis and other infections are also important. […] Prevention strategies include avoiding known risk factors: treating chronic hepatitis B/C, managing bile duct diseases, preventing liver fluke infections (through proper cooking of fish), quitting smoking, limiting alcohol intake, and controlling obesity and diabetes. Regular monitoring in high-risk patients can aid early detection.

• #10

  https://www.americanoncology.com/cancer-we-treat/prevention/bile-duct-cancer

  There is no way to prevent the occurrence of bile duct cancer. However, the risk of cholangiocarcinoma can be reduced by quitting smoking, managing underlying medical conditions, such as diabetes and liver disease, and lowering the risk of liver disease. […] People with an increased risk of bile duct cancer should consume alcohol in moderation, maintain a healthy weight, avoid exposure to toxic chemicals, and reduce liver inflammation through appropriate measures.

• #11

  https://link.springer.com/article/10.1007/BF02350901

  From both the therapeutic and diagnostic viewpoints, percutaneous transhepatic biliary drainage (PTBD) is crucial for the preoperative management of hilar cholangiocarcinoma. […] Prevention of posthepatectomy liver failure is the greatest challenge in the treatment of this disease. A multifactorial approach that combines several elements may provide sufficient data for determining the safe limits of surgery and for predicting posthepatectomy liver failure. Preoperative percutaneous transhepatic portal vein embolization (PTPE) is an effective method for preventing this intractable complication.

• #12 Major Hepatic Resection for Hilar Cholangiocarcinoma without Preoperative Biliary Drainage

  https://journal.waocp.org/article_24702.html

  Hilar cholangiocarcinoma is a rare cancer in western countries but very high incidence in the northeast of Thailand. The only chance to cure is surgical resection. Preoperative biliary drainage (PBD) for improving liver function to decrease perioperative morbidity and mortality is claimed to be beneficial. […] In our experience, it is safe in most patients with obstructive jaundice due to hilar cholangiocarcinoma to perform liver resection without preoperative biliary drainage (PBD).

• #13 Bacterial bile duct colonization in perihilar cholangiocarcinoma and its clinical significance | Scientific Reports

  https://www.nature.com/articles/s41598-021-82378-y

  Bacterial colonization is common in pCCA patients and reduced susceptibility of the bacteria to the intraoperative antibiotic prophylaxis is an independent predictor of postoperative abdominal infections. […] Adapting antibiotic prophylaxis might therefore have the potential to improve surgical outcome pCCA patients. […] We also identified reduced susceptibility of the bacterial isolates to the administered perioperative antibiotic prophylaxis as an independent predictor of postoperative abdominal infections in the multivariate analysis. […] Based on these observations we speculate that a change in the perioperative antibiotic prophylaxis might significantly reduce postoperative abdominal infections and subsequently improve the overall clinical outcome in pCCA patients. […] Our findings identify an important clinical factor with a potentially significant impact in the management of these high-risk patients and suggest a modification of the perioperatively applied antibiotics to improve postoperative outcome.

• #14 Palliation: Hilar cholangiocarcinoma

  https://www.wjgnet.com/1948-5182/full/v6/i8/559.htm

  It is important to institute antibiotic prophylaxis in patients with anticipated incomplete biliary drainage by any technique. Antibiotics should be continued in cases of incomplete biliary drainage. The choice of antibiotics should be based on local hospital data. […] A few exciting techniques have been used to improve the results of biliary stenting with the aim of delaying stent blockage and prolonging patient survival. These techniques include photodynamic therapy, radiofrequency ablation and chemo/radiotherapy.

• #14 Palliation: Hilar cholangiocarcinoma

  https://www.wjgnet.com/1948-5182/full/v6/i8/559.htm

  The majority of patients with hilar cholangiocarcinoma present in advanced stages and are candidates for palliation only. The techniques of palliation, primarily at endoscopy or by percutaneous techniques, are evolving as better stents become available. Alternate techniques, such as endosonography-guided procedures, are also becoming popular. Photodynamic therapy and radio-frequency ablation are also used to improve the results of biliary stents. […] Not every patient with unresectable HC needs palliative intervention. Patients with complications of cholangitis and intractable pruritus are definite candidates for palliation. Palliation is also often performed in patients with abdominal pain and high bilirubin with the hope of ameliorating their pain and sense of well-being, respectively. There are three established methods for the palliation of HC: endoscopic insertion of a stent, percutaneous placement of biliary drainage and surgical bypass. Endosonography-guided procedures have been evolving as alternatives to these standard techniques.

• #15 「Cholangiocarcinoma Treatment」Symptoms, Causes and Examination | Heal

  https://heal-oncology.com/cancer-type/cholangiocarcinoma/?lang=en

  As mentioned earlier, the exact cause of cholangiocarcinoma remains unclear, and no specific prevention method has been established. However, to reduce risk factors, you should avoid or quit smoking, limit alcohol consumption, maintain a healthy weight, and take measures to prevent liver diseases, thereby lowering the chances of developing cholangiocarcinoma.

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