Materiały źródłowe

• #1 Low White Blood Cell Count (Leukopenia): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/17706-low-white-blood-cell-count

  Leukopenia (low white blood cell count) happens when you have a lower-than-normal number of white blood cells. Specifically, you have fewer neutrophils than normal. Neutrophils are white blood cells that act as your immune systems first line of defense. Without enough white blood cells, youre more vulnerable to developing infections. […] Leukopenia doesnt have symptoms but it can cause infections that have the following symptoms: Fever and chills. Swelling and redness. Mouth sores. Red or white patches in your mouth. Sore throat. Severe cough or shortness of breath. Painful urination or pee that smells bad. Diarrhea. Cuts or sores that drain pus. Unusual vaginal discharge or itching. […] Your prognosis, or expected outcome, depends on why you have leukopenia. For example, you may have leukopenia because you have a viral infection. In that case, your white blood cell count should return to normal once youre over your infection. If your white blood cell count is low because youre receiving cancer treatment, your prognosis depends on your cancer diagnosis and treatment. […] Leukopenia increases your risk of developing infections, so you should contact your healthcare provider if you have leukopenia and think you may have an infection.

• #2 Low White Blood Cell Count: Causes and Solutions

  https://www.webmd.com/cancer/white-blood-cell-count-low

  A blood test that shows a WBC count of less than 4,000 per microliter (some labs say less than 4,500) could mean your body may not be able to fight infection the way it should. A low number is called leukopenia or neutropenia. Leukopenia can either be acute or chronic. […] You may not have any symptoms from having a low WBC count, but it leaves you prone to infections. As a result, you could have: Fever, Rashes, Mouth ulcers that don’t heal, Sores around the anus, Pneumonia and other severe illnesses, Tiredness. […] Symptoms could come and go if your WBC count is rising and falling, due to say, a medication dose.

• #3 Leukopenia: Types, Symptoms, Causes, Treatment & More

  https://www.healthline.com/health/leukopenia

  Leukopenia is a low white blood cell count. It doesnt always cause symptoms, but it can lead to serious complications. […] You probably wont notice any signs of leukopenia. But if your WBC counts are very low, you may have signs of infection, including: a fever of 100.4F (38C) or above, chills, sweating, sore throat, cough or shortness of breath, an area of your body thats become red, swollen, or painful, an injury thats draining pus, mouth sores or white patches in your mouth, painful urination. […] Because leukopenia involves low levels of infection-fighting immune cells, it can cause some potentially serious complications if left untreated. Some of the complications of leukopenia include: needing to delay cancer treatment because of a mild infection, sepsis, a life threatening response by your body to an infection, septicemia, which is a serious bloodstream infection, recurrent or prolonged infections, premature death.

• #4 Low white blood cell count (neutropenia) | Canadian Cancer Society

  https://cancer.ca/en/treatments/side-effects/low-white-blood-cell-count

  Neutropenia and leukopenia are terms used to refer to lowered numbers of white blood cells (WBCs) in the blood. WBCs help the body fight infection and disease. When WBC counts are low, there is a higher risk of infection. […] A person has leukopenia when the total WBC count is less than 3.0 x 10 9/ L. A person has neutropenia when the ANC is less than 1.9 x 10 9/ L. The risk of developing an infection is greater when the ANC is less than 1.5 x 10 9/ L. The risk increases as the neutrophil level drops and the longer it remains low. An infection is likely to occur if the ANC is less than 0.5 x 10 9/ L. […] Once the WBC count drops, it remains low for 710 days. The lowest level that blood cell counts reach is called the nadir. During nadir, the bodys resistance to infection is weakest. It is important to do everything possible to lower the chances of infection and to seek immediate treatment even if you think you have an infection.

• #5 Low white blood cell count (neutropenia) | Canadian Cancer Society

  https://cancer.ca/en/treatments/side-effects/low-white-blood-cell-count

  Neutropenia and leukopenia are terms used to refer to lowered numbers of white blood cells (WBCs) in the blood. WBCs help the body fight infection and disease. When WBC counts are low, there is a higher risk of infection. […] A person has leukopenia when the total WBC count is less than 3.0 x 10 9/ L. A person has neutropenia when the ANC is less than 1.9 x 10 9/ L. The risk of developing an infection is greater when the ANC is less than 1.5 x 10 9/ L. The risk increases as the neutrophil level drops and the longer it remains low. An infection is likely to occur if the ANC is less than 0.5 x 10 9/ L. […] Once the WBC count drops, it remains low for 710 days. The lowest level that blood cell counts reach is called the nadir. During nadir, the bodys resistance to infection is weakest. It is important to do everything possible to lower the chances of infection and to seek immediate treatment even if you think you have an infection.

• #6 Low white blood cell count and cancer: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/patientinstructions/000675.htm

  White blood cells (WBCs) fight infections from bacteria, viruses, fungi, and other germs. One important type of WBC is the neutrophil. These cells are made in the bone marrow and travel in the blood throughout the body. They sense infections, gather at sites of infection, and destroy the germs. […] When the body has too few neutrophils, the condition is called neutropenia. This makes it harder for the body to fight off infection, and a person is more likely to get sick. In general, an adult who has fewer than 1,000 neutrophils in a microliter of blood has neutropenia. […] If the neutrophil count is very low, fewer than 500 neutrophils in a microliter of blood, it is called severe neutropenia. When the neutrophil count gets this low, even the bacteria normally living in a person’s mouth, skin, and gut can cause serious infections.

• #7 Leukopenia (Low white blood cell count): Causes and more

  https://www.medicalnewstoday.com/articles/320299

  A person with leukopenia has a low number of white blood cells, or leukocytes, in their blood. A low white blood cell count may make a person more likely to contract an infection. […] A person may not show symptoms if they have a low white blood cell count. However, repeated infections may indicate leukopenia. The symptoms of infection include: fever, sweating, chills, toothache, sore throat, mouth ulcers that are difficult to heal, tiredness, flu-like symptoms, rash. […] Although leukopenia has no symptoms, it makes a person more susceptible to infections. As a result, a person should contact a doctor if they develop recurrent infections.

• #8 When to Worry About Low Lymphocytes on a Blood Test

  https://www.cancercenter.com/community/blog/2023/05/when-to-worry-about-low-lymphocytes

  Low lymphocytes may be caused by any number of conditions, including cancer. […] Learning you have low lymphocyte levels may be cause for concern. […] Most of the time, lymphocytopenia doesn’t often cause symptoms and is detected during a routine health checkup or when you’re being tested for something else. […] The biggest concern with low lymphocytes is that it may raise your risk for more serious infections, because it means your immune system isn’t functioning the way it should. […] Most of the time, patients don’t experience any noticeable symptoms of lymphocytopenia. If symptoms do occur, they may include, either alone or in combination: Frequent infections, such as pneumonia, Unusual infections that typically don’t cause problems for people with a healthy immune system, Infections that won’t go away, Swollen lymph nodes (particularly in the neck or groin), A larger-than-normal spleen, Skin conditions, like eczema and alopecia (hair loss), Joint pain and swelling, Signs of a viral infection, like a fever, cough or runny nose. […] Therefore, a low lymphocyte count may predispose you to certain infections.

• #9 Low white blood cell count (neutropenia) | Canadian Cancer Society

  https://cancer.ca/en/treatments/side-effects/low-white-blood-cell-count

  Leukopenia and neutropenia do not cause any symptoms. People with cancer usually find out they have low white blood cell counts from a blood test or when they get an infection. An infection can start in almost any part of the body, but many occur in the skin, mucous membranes, digestive tract or respiratory tract. […] The most common signs and symptoms of an infection include: fever and chills, swelling and redness, mouth sores, red or white patches in the mouth, sore throat, severe cough or shortness of breath, pain or burning when urinating or foul-smelling urine, diarrhea, pain, redness or swelling of the rectal area, drainage, pus, redness or swelling from a cut, sore, incision, venous access device or drainage tube, unusual vaginal discharge or itching. […] Sometimes a fever is the only sign of infection, but a person can have an infection without having a fever or chills.

• #10 Low White Blood Cell Counts | Neutropenia | American Cancer Society

  https://www.cancer.org/cancer/managing-cancer/side-effects/low-blood-counts/neutropenia.html

  People with a low white blood cell count have a condition called neutropenia. Neutropenia itself doesn’t usually cause any signs or symptoms. If you are getting medicine or other treatments that often cause neutropenia, your cancer care team might check your white blood cell counts with blood tests. Managing neutropenia depends on the cause. But if you have signs of an infection and have a low WBC count, you might be started on a treatment before they know what is causing it. The nadir usually occurs about 7 to 10 days after getting chemo. This is when a person is most at risk for a severe infection. […] Call your cancer care team or get medical help if you have: A temperature over 100.4 F, Chills or sweating, New or worsening confusion, Dizziness, lightheadedness, or have been falling down, Chest pain, Trouble breathing even at rest.

• #11 What are the symptoms of low blood counts? | Aplastic Anemia and MDS International Foundation (AAMDSIF)

  https://www.aamds.org/questions/what-are-symptoms-low-blood-counts

  The symptoms of bone marrow failure diseases like aplastic anemia, MDS and PNH are caused by low blood counts. The specific symptoms depend on which type of blood cell is affected. […] A low white blood cell count is called neutropenia. If you have a low white blood cell count, you may: […] Have repeated fevers and infections. […] Get bladder infections that may make it painful to pass urine, or make you urinate more often. […] Get lung infections that cause coughing and difficulty breathing. […] Get mouth sores. […] Get sinus infections and a stuffy nose. […] Get skin infections.

• #12 Symptoms of Low White Blood Counts – Breast Cancer

  https://www.amoena.com/au/your-lifestyle/recognizing-symptoms-low-white-blood-counts/

  Low white blood cell counts (WBC) can be particularly problematic, because your white blood cell count is closely tied to your immune systems ability to protect you from infection. […] The importance of keeping your WBC as high as possible is quite significant when your body is already enduring surgeries, chemotherapy and other cancer treatments. […] Its difficult to tell that your WBC has been compromised because you may not have the usual signs or symptoms associated with an infection. […] Many women say they didnt realize until they had blood work done that their WBC was low but they knew something was wrong because they felt so awful. Its not uncommon for someone with a low WBC to feel like they have a really bad case of the flu. Your body may ache from head to toe. You may feel like you just want to sleep, regardless of how much rest youve had. You may feel weak, dizzy, and generally depressed.

• #13 Leukopenia: Types, Symptoms, Causes, Treatment & More

  https://www.healthline.com/health/leukopenia

  Leukopenia is a low white blood cell count. It doesnt always cause symptoms, but it can lead to serious complications. […] You probably wont notice any signs of leukopenia. But if your WBC counts are very low, you may have signs of infection, including: a fever of 100.4F (38C) or above, chills, sweating, sore throat, cough or shortness of breath, an area of your body thats become red, swollen, or painful, an injury thats draining pus, mouth sores or white patches in your mouth, painful urination. […] Because leukopenia involves low levels of infection-fighting immune cells, it can cause some potentially serious complications if left untreated. Some of the complications of leukopenia include: needing to delay cancer treatment because of a mild infection, sepsis, a life threatening response by your body to an infection, septicemia, which is a serious bloodstream infection, recurrent or prolonged infections, premature death.

• #14 Low white blood cell count (neutropenia) | Canadian Cancer Society

  https://cancer.ca/en/treatments/side-effects/low-white-blood-cell-count

  Leukopenia and neutropenia do not cause any symptoms. People with cancer usually find out they have low white blood cell counts from a blood test or when they get an infection. An infection can start in almost any part of the body, but many occur in the skin, mucous membranes, digestive tract or respiratory tract. […] The most common signs and symptoms of an infection include: fever and chills, swelling and redness, mouth sores, red or white patches in the mouth, sore throat, severe cough or shortness of breath, pain or burning when urinating or foul-smelling urine, diarrhea, pain, redness or swelling of the rectal area, drainage, pus, redness or swelling from a cut, sore, incision, venous access device or drainage tube, unusual vaginal discharge or itching. […] Sometimes a fever is the only sign of infection, but a person can have an infection without having a fever or chills.

• #15 Leukopenia: Types, Symptoms, Causes, Treatment & More

  https://www.healthline.com/health/leukopenia

  Leukopenia is a low white blood cell count. It doesnt always cause symptoms, but it can lead to serious complications. […] You probably wont notice any signs of leukopenia. But if your WBC counts are very low, you may have signs of infection, including: a fever of 100.4F (38C) or above, chills, sweating, sore throat, cough or shortness of breath, an area of your body thats become red, swollen, or painful, an injury thats draining pus, mouth sores or white patches in your mouth, painful urination. […] Because leukopenia involves low levels of infection-fighting immune cells, it can cause some potentially serious complications if left untreated. Some of the complications of leukopenia include: needing to delay cancer treatment because of a mild infection, sepsis, a life threatening response by your body to an infection, septicemia, which is a serious bloodstream infection, recurrent or prolonged infections, premature death.

• #16 What are the symptoms of low blood counts? | Aplastic Anemia and MDS International Foundation (AAMDSIF)

  https://www.aamds.org/questions/what-are-symptoms-low-blood-counts

  The symptoms of bone marrow failure diseases like aplastic anemia, MDS and PNH are caused by low blood counts. The specific symptoms depend on which type of blood cell is affected. […] A low white blood cell count is called neutropenia. If you have a low white blood cell count, you may: […] Have repeated fevers and infections. […] Get bladder infections that may make it painful to pass urine, or make you urinate more often. […] Get lung infections that cause coughing and difficulty breathing. […] Get mouth sores. […] Get sinus infections and a stuffy nose. […] Get skin infections.

• #17 Low white blood cell count and cancer: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/patientinstructions/000675.htm

  A person with cancer can develop a low WBC count from the cancer or from treatment for the cancer. Cancer may be in the bone marrow, causing fewer neutrophils to be made. The WBC count can also go down when cancer is treated with chemotherapy drugs, which slow bone marrow production of healthy WBCs. […] If you have any of the following symptoms, contact your health care provider: Fevers, chills, or sweats. Diarrhea that does not go away or is bloody. Severe nausea and vomiting. Being unable to eat or drink. Extreme weakness. Redness, swelling, or drainage from any place where you have an IV line inserted into your body. A new skin rash or blisters. Pain in your stomach area. A very bad headache or one that does not go away. A cough that is getting worse. Trouble breathing when you are at rest or when you are doing simple tasks. Burning when you urinate.

• #18 Low white blood cell count (neutropenia) | Canadian Cancer Society

  https://cancer.ca/en/treatments/side-effects/low-white-blood-cell-count

  Leukopenia and neutropenia do not cause any symptoms. People with cancer usually find out they have low white blood cell counts from a blood test or when they get an infection. An infection can start in almost any part of the body, but many occur in the skin, mucous membranes, digestive tract or respiratory tract. […] The most common signs and symptoms of an infection include: fever and chills, swelling and redness, mouth sores, red or white patches in the mouth, sore throat, severe cough or shortness of breath, pain or burning when urinating or foul-smelling urine, diarrhea, pain, redness or swelling of the rectal area, drainage, pus, redness or swelling from a cut, sore, incision, venous access device or drainage tube, unusual vaginal discharge or itching. […] Sometimes a fever is the only sign of infection, but a person can have an infection without having a fever or chills.

• #19 Low White Blood Cell Count (Leukopenia): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/17706-low-white-blood-cell-count

  Leukopenia (low white blood cell count) happens when you have a lower-than-normal number of white blood cells. Specifically, you have fewer neutrophils than normal. Neutrophils are white blood cells that act as your immune systems first line of defense. Without enough white blood cells, youre more vulnerable to developing infections. […] Leukopenia doesnt have symptoms but it can cause infections that have the following symptoms: Fever and chills. Swelling and redness. Mouth sores. Red or white patches in your mouth. Sore throat. Severe cough or shortness of breath. Painful urination or pee that smells bad. Diarrhea. Cuts or sores that drain pus. Unusual vaginal discharge or itching. […] Your prognosis, or expected outcome, depends on why you have leukopenia. For example, you may have leukopenia because you have a viral infection. In that case, your white blood cell count should return to normal once youre over your infection. If your white blood cell count is low because youre receiving cancer treatment, your prognosis depends on your cancer diagnosis and treatment. […] Leukopenia increases your risk of developing infections, so you should contact your healthcare provider if you have leukopenia and think you may have an infection.

• #20 Quick Facts:Low White Blood Cell Count – Merck Manual Consumer Version

  https://www.merckmanuals.com/home/quick-facts-blood-disorders/white-blood-cell-disorders/low-white-blood-cell-count

  A low white blood cell count has no specific symptoms. You get symptoms because you develop frequent infections. Sometimes the infections are unusual ones that most people don’t get. […] Symptoms of infections can start suddenly or slowly and can include: Fever, Rash, Swollen lymph nodes, Painful sores in your mouth and anus (the opening at the end of the digestive tract where stool comes out). […] A low white blood cell count puts you at increased risk of infection, which can be life-threatening.

• #21 Low white blood cell count (neutropenia) | Canadian Cancer Society

  https://cancer.ca/en/treatments/side-effects/low-white-blood-cell-count

  Leukopenia and neutropenia do not cause any symptoms. People with cancer usually find out they have low white blood cell counts from a blood test or when they get an infection. An infection can start in almost any part of the body, but many occur in the skin, mucous membranes, digestive tract or respiratory tract. […] The most common signs and symptoms of an infection include: fever and chills, swelling and redness, mouth sores, red or white patches in the mouth, sore throat, severe cough or shortness of breath, pain or burning when urinating or foul-smelling urine, diarrhea, pain, redness or swelling of the rectal area, drainage, pus, redness or swelling from a cut, sore, incision, venous access device or drainage tube, unusual vaginal discharge or itching. […] Sometimes a fever is the only sign of infection, but a person can have an infection without having a fever or chills.

• #22 Low White Blood Cell Count (Neutropenia): What it Means

  https://www.verywellhealth.com/low-white-blood-cell-count-5222890

  Symptoms you may experience from complications of having a low white count include: Fatigue, Fevers, chills, Sore throat, coughing, difficulty breathing, Nausea, vomiting, diarrhea, Painful urination, blood in the urine, urinary frequency, Skin sores that dont heal, Mouth sores, mouth pain. […] Sometimes a lack of white blood cells leads to opportunistic infections, which are infections that wouldnt normally develop in a person with a healthy immune system. […] A low white blood cell count is often a sign of chronic disease. But sometimes medications or infections can temporarily cause this problem due to the destruction of white blood cells. This should resolve once the infection clears up or the medication is discontinued. […] A low white blood cell count can be a consequence of serious diseases or medications such as chemotherapy. It can lead to harmful health problems including infections, slow healing, and cancer. […] A low white blood cell count doesn’t cause symptoms, but the complications can. These often need to be treated, and management of low white blood cells is important to prevent serious complications from occurring.

• #23 Leukopenia

  https://levy.health/resource-center/lexicon/leukopenia/

  Leukopenia means that you have a low white blood cell count. White blood cells, or leukocytes, are vital to your immune system. They defend you from invaders like viruses and bacteria. […] A low white blood cell count usually refers to a low level of neutrophils (infection-fighting white blood cells) this is known as neutropenia. Having too few of these cells makes you more vulnerable to infections. […] Leukopenia doesnt cause symptoms but makes you more prone to infections. You may experience the following sickness symptoms: Fever and chills, Swelling, Mouth sores, Cough, Painful urination or strongly smelling pee, Diarrhea, Wounds that pus, Vaginal discharge or itching, Trouble breathing, Abdominal or rectal pain. […] Low white blood cell count is treatable, and the prognosis is quite good. Once your doctor figures out whats leading to your low white blood cell count, they will treat the underlying cause.

• #24 White Blood Cell Count: Normal, High, and Low Counts

  https://www.healthline.com/health/wbc-count

  A normal white blood cell count is 5,000 to 10,000 for people assigned male at birth and 4,500 to 11,000 for people assigned female at birth. […] A white blood cell count can detect hidden infections within your body and alert doctors to undiagnosed medical conditions, such as autoimmune diseases, immune deficiencies, and blood disorders. […] If your test results are abnormal, it may mean that your numbers are higher or lower than the normal range. […] Low white blood cell count is referred to as leukopenia. […] Symptoms of a low WBC count can include fatigue, body aches, fever, chills, and headache. […] Having neutropenia may put you at an increased risk for infection. You may not have enough white blood cells to protect you from germs and bacteria.

• #25 White Blood Cell Disorders | Blood Disorders

  https://health.ucdavis.edu/conditions/white-blood-cell-disorders

  Symptoms of White Blood Cell Disorders […] Symptoms vary based on the underlying cause and whether you have too many or too few white blood cells. […] Common Symptoms of Low White Blood Cell Count (Leukopenia) These symptoms could be signs of leukopenia: Body aches, Chills and fever, Cough and sore throat, Dizziness, Fatigue, Sores on your mouth or skin, Trouble breathing. […] Bone Marrow Cancer Cancers that attack your bone marrow, such as lymphoma, leukemia and multiple myeloma, may lead to a low white blood cell count. […] Immune System Disorders Immune system disorders, such as HIV/AIDS, can cause a low white blood cell count. […] Liver or Spleen Diseases Liver disease or spleen disease may lead to a low white blood cell count. […] Vitamin Deficiency A lack of vitamins, such as vitamin B12, can lead to a low blood cell count.

• #26 Low white blood cell count

  https://www.nhs.uk/conditions/low-white-blood-cell-count/

  A low white blood cell count usually means your body is not making enough white blood cells. It can increase your risk of getting infections. […] A low white blood cell count does not always cause any symptoms. The main symptom is getting frequent infections. Signs of an infection may include: a high temperature, chills and shivering, sore throat, mouth sores that keep coming back, toothache, skin rashes, tiredness, flu-like symptoms. […] Occasionally, infections can lead to a life-threatening condition called sepsis.

• #27 When to Worry About Low Lymphocytes on a Blood Test

  https://www.cancercenter.com/community/blog/2023/05/when-to-worry-about-low-lymphocytes

  Low lymphocytes may be caused by any number of conditions, including cancer. […] Learning you have low lymphocyte levels may be cause for concern. […] Most of the time, lymphocytopenia doesn’t often cause symptoms and is detected during a routine health checkup or when you’re being tested for something else. […] The biggest concern with low lymphocytes is that it may raise your risk for more serious infections, because it means your immune system isn’t functioning the way it should. […] Most of the time, patients don’t experience any noticeable symptoms of lymphocytopenia. If symptoms do occur, they may include, either alone or in combination: Frequent infections, such as pneumonia, Unusual infections that typically don’t cause problems for people with a healthy immune system, Infections that won’t go away, Swollen lymph nodes (particularly in the neck or groin), A larger-than-normal spleen, Skin conditions, like eczema and alopecia (hair loss), Joint pain and swelling, Signs of a viral infection, like a fever, cough or runny nose. […] Therefore, a low lymphocyte count may predispose you to certain infections.

• #28 Chronic neutropenia | Immune Deficiency Foundation

  https://primaryimmune.org/understanding-primary-immunodeficiency/types-of-pi/chronic-neutropenia

  A characteristic feature of chronic neutropenia, especially if it is severe, is a lack or decrease of pus at the site of infections. […] Chronic neutropenia looks very different depending on how low a persons neutrophil level is in the blood. […] The risk of infection due to neutropenia correlates with both its severity and duration. […] Those with chronic neutropenia are also at risk of eventually developing bone marrow or blood cancers like myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML).

• #29 Low White Blood Cell Count (Leukopenia): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/17706-low-white-blood-cell-count

  Leukopenia (low white blood cell count) happens when you have a lower-than-normal number of white blood cells. Specifically, you have fewer neutrophils than normal. Neutrophils are white blood cells that act as your immune systems first line of defense. Without enough white blood cells, youre more vulnerable to developing infections. […] Leukopenia doesnt have symptoms but it can cause infections that have the following symptoms: Fever and chills. Swelling and redness. Mouth sores. Red or white patches in your mouth. Sore throat. Severe cough or shortness of breath. Painful urination or pee that smells bad. Diarrhea. Cuts or sores that drain pus. Unusual vaginal discharge or itching. […] Your prognosis, or expected outcome, depends on why you have leukopenia. For example, you may have leukopenia because you have a viral infection. In that case, your white blood cell count should return to normal once youre over your infection. If your white blood cell count is low because youre receiving cancer treatment, your prognosis depends on your cancer diagnosis and treatment. […] Leukopenia increases your risk of developing infections, so you should contact your healthcare provider if you have leukopenia and think you may have an infection.

• #30 Low White Blood Cell Counts | Neutropenia | American Cancer Society

  https://www.cancer.org/cancer/managing-cancer/side-effects/low-blood-counts/neutropenia.html

  People with a low white blood cell count have a condition called neutropenia. Neutropenia itself doesn’t usually cause any signs or symptoms. If you are getting medicine or other treatments that often cause neutropenia, your cancer care team might check your white blood cell counts with blood tests. Managing neutropenia depends on the cause. But if you have signs of an infection and have a low WBC count, you might be started on a treatment before they know what is causing it. The nadir usually occurs about 7 to 10 days after getting chemo. This is when a person is most at risk for a severe infection. […] Call your cancer care team or get medical help if you have: A temperature over 100.4 F, Chills or sweating, New or worsening confusion, Dizziness, lightheadedness, or have been falling down, Chest pain, Trouble breathing even at rest.

• #31 Low white blood cell count (neutropenia) | Canadian Cancer Society

  https://cancer.ca/en/treatments/side-effects/low-white-blood-cell-count

  Neutropenia and leukopenia are terms used to refer to lowered numbers of white blood cells (WBCs) in the blood. WBCs help the body fight infection and disease. When WBC counts are low, there is a higher risk of infection. […] A person has leukopenia when the total WBC count is less than 3.0 x 10 9/ L. A person has neutropenia when the ANC is less than 1.9 x 10 9/ L. The risk of developing an infection is greater when the ANC is less than 1.5 x 10 9/ L. The risk increases as the neutrophil level drops and the longer it remains low. An infection is likely to occur if the ANC is less than 0.5 x 10 9/ L. […] Once the WBC count drops, it remains low for 710 days. The lowest level that blood cell counts reach is called the nadir. During nadir, the bodys resistance to infection is weakest. It is important to do everything possible to lower the chances of infection and to seek immediate treatment even if you think you have an infection.

• #32 Leukopenia: Types, Symptoms, Causes, Treatment & More

  https://www.healthline.com/health/leukopenia

  Leukopenia is a low white blood cell count. It doesnt always cause symptoms, but it can lead to serious complications. […] You probably wont notice any signs of leukopenia. But if your WBC counts are very low, you may have signs of infection, including: a fever of 100.4F (38C) or above, chills, sweating, sore throat, cough or shortness of breath, an area of your body thats become red, swollen, or painful, an injury thats draining pus, mouth sores or white patches in your mouth, painful urination. […] Because leukopenia involves low levels of infection-fighting immune cells, it can cause some potentially serious complications if left untreated. Some of the complications of leukopenia include: needing to delay cancer treatment because of a mild infection, sepsis, a life threatening response by your body to an infection, septicemia, which is a serious bloodstream infection, recurrent or prolonged infections, premature death.

• #33 Low White Blood Cell Count (Neutropenia): What it Means

  https://www.verywellhealth.com/low-white-blood-cell-count-5222890

  Symptoms you may experience from complications of having a low white count include: Fatigue, Fevers, chills, Sore throat, coughing, difficulty breathing, Nausea, vomiting, diarrhea, Painful urination, blood in the urine, urinary frequency, Skin sores that dont heal, Mouth sores, mouth pain. […] Sometimes a lack of white blood cells leads to opportunistic infections, which are infections that wouldnt normally develop in a person with a healthy immune system. […] A low white blood cell count is often a sign of chronic disease. But sometimes medications or infections can temporarily cause this problem due to the destruction of white blood cells. This should resolve once the infection clears up or the medication is discontinued. […] A low white blood cell count can be a consequence of serious diseases or medications such as chemotherapy. It can lead to harmful health problems including infections, slow healing, and cancer. […] A low white blood cell count doesn’t cause symptoms, but the complications can. These often need to be treated, and management of low white blood cells is important to prevent serious complications from occurring.

• #34 Low white blood cell count

  https://www.nhs.uk/conditions/low-white-blood-cell-count/

  A low white blood cell count usually means your body is not making enough white blood cells. It can increase your risk of getting infections. […] A low white blood cell count does not always cause any symptoms. The main symptom is getting frequent infections. Signs of an infection may include: a high temperature, chills and shivering, sore throat, mouth sores that keep coming back, toothache, skin rashes, tiredness, flu-like symptoms. […] Occasionally, infections can lead to a life-threatening condition called sepsis.

• #35 Leukopenia: Types, Symptoms, Causes, Treatment & More

  https://www.healthline.com/health/leukopenia

  Leukopenia is a low white blood cell count. It doesnt always cause symptoms, but it can lead to serious complications. […] You probably wont notice any signs of leukopenia. But if your WBC counts are very low, you may have signs of infection, including: a fever of 100.4F (38C) or above, chills, sweating, sore throat, cough or shortness of breath, an area of your body thats become red, swollen, or painful, an injury thats draining pus, mouth sores or white patches in your mouth, painful urination. […] Because leukopenia involves low levels of infection-fighting immune cells, it can cause some potentially serious complications if left untreated. Some of the complications of leukopenia include: needing to delay cancer treatment because of a mild infection, sepsis, a life threatening response by your body to an infection, septicemia, which is a serious bloodstream infection, recurrent or prolonged infections, premature death.

• #36 Leukopenia: Types, Symptoms, Causes, Treatment & More

  https://www.healthline.com/health/leukopenia

  Leukopenia is a low white blood cell count. It doesnt always cause symptoms, but it can lead to serious complications. […] You probably wont notice any signs of leukopenia. But if your WBC counts are very low, you may have signs of infection, including: a fever of 100.4F (38C) or above, chills, sweating, sore throat, cough or shortness of breath, an area of your body thats become red, swollen, or painful, an injury thats draining pus, mouth sores or white patches in your mouth, painful urination. […] Because leukopenia involves low levels of infection-fighting immune cells, it can cause some potentially serious complications if left untreated. Some of the complications of leukopenia include: needing to delay cancer treatment because of a mild infection, sepsis, a life threatening response by your body to an infection, septicemia, which is a serious bloodstream infection, recurrent or prolonged infections, premature death.

• #37 Neutropenia (low neutrophils) | Lymphoma Action

  https://lymphoma-action.org.uk/about-lymphoma-side-effects-treatment/neutropenia-low-neutrophils

  Neutropenic sepsis is a whole-body reaction to an infection. Neutropenic sepsis is a potentially life-threatening complication of being neutropenic. Not everyone with neutropenia develops neutropenic sepsis but it is important to know the signs and symptoms. If you notice any signs or symptoms of neutropenic sepsis, seek medical attention straight away. A common symptom of neutropenic sepsis is fever (a body temperature higher than 38C or 100.4F). […] Your medical team can give you information relevant to your situation and take any necessary precautions. If you develop neutropenic sepsis, you are likely to need to be admitted to hospital for treatment with IV (intravenous) antibiotics.

• #38 White Blood Cell Disorders | Blood Disorders

  https://health.ucdavis.edu/conditions/white-blood-cell-disorders

  Symptoms of White Blood Cell Disorders […] Symptoms vary based on the underlying cause and whether you have too many or too few white blood cells. […] Common Symptoms of Low White Blood Cell Count (Leukopenia) These symptoms could be signs of leukopenia: Body aches, Chills and fever, Cough and sore throat, Dizziness, Fatigue, Sores on your mouth or skin, Trouble breathing. […] Bone Marrow Cancer Cancers that attack your bone marrow, such as lymphoma, leukemia and multiple myeloma, may lead to a low white blood cell count. […] Immune System Disorders Immune system disorders, such as HIV/AIDS, can cause a low white blood cell count. […] Liver or Spleen Diseases Liver disease or spleen disease may lead to a low white blood cell count. […] Vitamin Deficiency A lack of vitamins, such as vitamin B12, can lead to a low blood cell count.

• #39 Low White Blood Cell Count and Leukemia | MyLeukemiaTeam

  https://www.myleukemiateam.com/resources/low-white-blood-cell-count-and-leukemia

  When someone has leukemia, their body overproduces WBCs. These extra leukemia cells dont function properly. Unlike their normal counterparts, they cant fight infection from viruses and bacteria, leaving the immune system vulnerable to attack. […] Certain types of leukemia are especially associated with a low WBC count. These include: Acute promyelocytic leukemia, Hairy cell leukemia, Acute megakaryoblastic leukemia. […] Any type of leukemia can eventually show low WBC counts due to bone marrow failure, a condition in which the bone marrow is unable to produce normal amounts of healthy blood cells. Additionally, a low WBC count could signal an infection. It can also mean the person is not getting good nutrition or enough iron. […] Both leukemia and some therapies to treat it can tax the immune system and reduce WBC levels. For example, chemotherapy is very effective at killing fast-growing cells, but it attacks both healthy blood cells and leukemia cells. Thats why low WBC counts are common during cancer treatment. A high blood cell count usually returns to normal on its own once treatment is over. […] Doctors monitor WBC counts in people with leukemia to track how the disease is responding to treatment or progressing.

• #40 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. Low levels of normal blood cells can be found on blood tests, and they can also cause symptoms. […] Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another. […] Fever often goes along with the infection. […] Although people with AML can have high white blood cell counts from excess numbers of leukemia cells, these cells don’t protect against infection the way normal white blood cells do.

• #41 Low White Blood Cell Count: 6 Common Causes – Tua Saúde

  https://www.tuasaude.com/en/low-white-blood-cell-count/

  A low white blood cell count is a common finding in systemic lupus erythematosus. This is due to the production of abnormal antibodies that can also stimulate the destruction of neutrophils and/or lymphocytes in the blood. […] Although this is a rare condition, myelodysplasia is a bone marrow disorder that can also cause a low white blood cell count, as well as a drop in red blood cell and/or platelet levels. Depending on the blood cells affected, patients can present with symptoms like fatigue, shortness of breath, heart palpitations, bleeding and, in the case of low leukocytes, an increased risk for infections.

• #42 Lupus and Blood Cell Disorders | HSS Rheumatology

  https://www.hss.edu/conditions_top-ten-points-about-lupus-and-blood-cell-disorders.asp

  Half of patients with SLE may develop leukopenia (decrease in white blood cells), especially one type of the white blood cells called lymphocytes, which are part of the special task force of the immune system. […] Leukopenia can lead to a higher risk of infections, especially bacterial, as the immune system is weakened. However, infections mostly occur when the white blood cell count is very low. Common general symptoms of an infection are fever, chills and sweats, and joint and muscle soreness. […] Depending on the severity of anemia that results, patients might have either no symptoms or multiple symptoms, which may include: fatigue, weakness, pale or yellowish skin and pale mucous membranes, shortness of breath, irregular heartbeats, a heart murmur caused by a change in the blood consistency, dizziness or lightheadedness, cold hands and feet. […] It should be mentioned that lupus patients can develop anemia, leukopenia, or thrombocytopenia due to reasons other than lupus, for example infection.

• #43 Leukopenia – Wikipedia

  https://en.wikipedia.org/wiki/Leukopenia

  Leukopenia is a decrease in the number of leukocytes (WBC). Found in the blood, they are the white blood cells, and are the body’s primary defense against an infection. Thus the condition of leukopenia places individuals at increased risk of infection. […] Symptoms may include: skin or mouth ulcers, sore throat, cough, difficulty in breathing, light-headedness, fever, chills, body aches. […] Low white cell count may be due to acute viral infections, such as a cold or influenza. It has been associated with chemotherapy, radiation therapy, myelofibrosis, aplastic anemia (failure of white cell, red cell and platelet production), stem cell transplant, bone marrow transplant, HIV, AIDS, and steroid use. […] Other causes of low white blood cell count include systemic lupus erythematosus, Hodgkin’s lymphoma, some types of cancer, typhoid, malaria, tuberculosis, dengue, rickettsial infections, enlargement of the spleen, folate deficiencies, psittacosis, sepsis, Sjgren syndrome and Lyme disease. […] Chemotherapy targets cells that grow rapidly, such as tumors, but can also affect white blood cells, because they are characterized by bone marrow as rapid growing. A common side effect of cancer treatment is neutropenia, the lowering of neutrophils (a specific type of white blood cell).

• #44

  https://www.koruhastanesi.com/leukocytes-what-is-high-and-low-count-3895-5

  Leukopenia, on the other hand, signifies a lower-than-normal white blood cell count, making the body more susceptible to infections. […] Leukopenia can manifest with symptoms such as: Frequent infections, Fatigue, Fever, Mouth sores, Unexplained bruises or bleeding. […] Several factors and conditions can lead to leukopenia: Viral Infections: Viruses like HIV, hepatitis, and Epstein-Barr virus can reduce white blood cell counts. Autoimmune Disorders: Conditions like lupus or rheumatoid arthritis can cause the immune system to attack white blood cells. Medications: Certain medications, including chemotherapy drugs, can suppress white blood cell production. Bone Marrow Disorders: Disorders affecting the bone marrow, such as aplastic anemia, can lead to a decrease in white blood cell production.

• #45 White Blood Count (WBC): MedlinePlus Medical TestLock

  https://medlineplus.gov/lab-tests/white-blood-count-wbc/

  A white blood count is most often used to help diagnose or monitor disorders related to having a high white blood cell count or low white blood cell count. […] Disorders related to having a low white blood count include: Diseases of the immune system, such as HIV, Lymphoma, a cancer of the bone marrow, Diseases of the liver or spleen. […] Conditions that may cause a low white blood count, also called leukopenia, include: Bone marrow damage. This may be caused by infection, disease, or treatments such as chemotherapy, Cancers that affect the bone marrow, An autoimmune disorder, such as lupus, HIV.

• #46 Why Is My White Blood Cell Count High?

  https://www.medicinenet.com/why_is_my_white_blood_cell_count_high/article.htm

  Various conditions can cause your white blood cell count to become low. These include […] Viral infections […] Tuberculosis […] Human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) […] Aplastic anemia (a disorder when your bone marrow stops making new blood cells) […] Exposure to certain chemicals such as benzene and pesticides […] Chemotherapy (a cancer therapy that uses anticancer medications) […] Radiation (a cancer therapy that makes use of high-energy waves to destroy the cancerous cells) […] Bone marrow transplant […] The immune system in some autoimmune disorders fails to differentiate between germs that attack the body and the body’s own cells such as the white blood cells. These conditions can cause your white blood cell count to become low. […] Inflammation of the spleen due to infections (such as malaria) and blood clots can lower your white blood cell count. […] If it becomes overactive (medically known as hypersplenism), it removes all types of blood cells, whether they are damaged or healthy, including the white blood cells from your body. This lowers your white blood cells count. […] Not eating well can result in vitamin deficiencies such as those of vitamin B12, folic acid/folate, copper, and zinc. These nutritional deficiencies can cause the white blood cell count to become low.

• #47 White Blood Cell Disorders | Blood Disorders

  https://health.ucdavis.edu/conditions/white-blood-cell-disorders

  Symptoms of White Blood Cell Disorders […] Symptoms vary based on the underlying cause and whether you have too many or too few white blood cells. […] Common Symptoms of Low White Blood Cell Count (Leukopenia) These symptoms could be signs of leukopenia: Body aches, Chills and fever, Cough and sore throat, Dizziness, Fatigue, Sores on your mouth or skin, Trouble breathing. […] Bone Marrow Cancer Cancers that attack your bone marrow, such as lymphoma, leukemia and multiple myeloma, may lead to a low white blood cell count. […] Immune System Disorders Immune system disorders, such as HIV/AIDS, can cause a low white blood cell count. […] Liver or Spleen Diseases Liver disease or spleen disease may lead to a low white blood cell count. […] Vitamin Deficiency A lack of vitamins, such as vitamin B12, can lead to a low blood cell count.

• #48 Why Is My White Blood Cell Count High?

  https://www.medicinenet.com/why_is_my_white_blood_cell_count_high/article.htm

  Various conditions can cause your white blood cell count to become low. These include […] Viral infections […] Tuberculosis […] Human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) […] Aplastic anemia (a disorder when your bone marrow stops making new blood cells) […] Exposure to certain chemicals such as benzene and pesticides […] Chemotherapy (a cancer therapy that uses anticancer medications) […] Radiation (a cancer therapy that makes use of high-energy waves to destroy the cancerous cells) […] Bone marrow transplant […] The immune system in some autoimmune disorders fails to differentiate between germs that attack the body and the body’s own cells such as the white blood cells. These conditions can cause your white blood cell count to become low. […] Inflammation of the spleen due to infections (such as malaria) and blood clots can lower your white blood cell count. […] If it becomes overactive (medically known as hypersplenism), it removes all types of blood cells, whether they are damaged or healthy, including the white blood cells from your body. This lowers your white blood cells count. […] Not eating well can result in vitamin deficiencies such as those of vitamin B12, folic acid/folate, copper, and zinc. These nutritional deficiencies can cause the white blood cell count to become low.

• #49 Low White Blood Cell Count: 6 Common Causes – Tua Saúde

  https://www.tuasaude.com/en/low-white-blood-cell-count/

  A low white blood cell count is a common finding in systemic lupus erythematosus. This is due to the production of abnormal antibodies that can also stimulate the destruction of neutrophils and/or lymphocytes in the blood. […] Although this is a rare condition, myelodysplasia is a bone marrow disorder that can also cause a low white blood cell count, as well as a drop in red blood cell and/or platelet levels. Depending on the blood cells affected, patients can present with symptoms like fatigue, shortness of breath, heart palpitations, bleeding and, in the case of low leukocytes, an increased risk for infections.

• #50 Chronic neutropenia | Immune Deficiency Foundation

  https://primaryimmune.org/understanding-primary-immunodeficiency/types-of-pi/chronic-neutropenia

  People with chronic neutropenia have low levels of white blood cells called neutrophils, and the condition is both a rare blood disorder and a rare type of primary immunodeficiency (PI). […] People with chronic neutropenia have a low number of neutrophils, the most common type of white blood cell, in their blood for longer than three months. […] The lower a persons neutrophil count, the greater their risk of infection. […] Symptoms associated with chronic neutropenia include recurring fevers, mouth sores (ulcers), inflammation of the tissues that surround and support the teeth (periodontitis), and inflammation of the sinuses (sinusitis), throat (pharyngitis), skin (dermatitis), and/or inner ear (otitis). […] Due to low levels of neutrophils, people with neutropenia may be more likely to get recurring bacterial infections that, in some people, result in life-threatening complications like sepsis.

• #51 Leukopenia – Wikipedia

  https://en.wikipedia.org/wiki/Leukopenia

  Leukopenia is a decrease in the number of leukocytes (WBC). Found in the blood, they are the white blood cells, and are the body’s primary defense against an infection. Thus the condition of leukopenia places individuals at increased risk of infection. […] Symptoms may include: skin or mouth ulcers, sore throat, cough, difficulty in breathing, light-headedness, fever, chills, body aches. […] Low white cell count may be due to acute viral infections, such as a cold or influenza. It has been associated with chemotherapy, radiation therapy, myelofibrosis, aplastic anemia (failure of white cell, red cell and platelet production), stem cell transplant, bone marrow transplant, HIV, AIDS, and steroid use. […] Other causes of low white blood cell count include systemic lupus erythematosus, Hodgkin’s lymphoma, some types of cancer, typhoid, malaria, tuberculosis, dengue, rickettsial infections, enlargement of the spleen, folate deficiencies, psittacosis, sepsis, Sjgren syndrome and Lyme disease. […] Chemotherapy targets cells that grow rapidly, such as tumors, but can also affect white blood cells, because they are characterized by bone marrow as rapid growing. A common side effect of cancer treatment is neutropenia, the lowering of neutrophils (a specific type of white blood cell).

• #52 Low white blood cell count and cancer: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/patientinstructions/000675.htm

  A person with cancer can develop a low WBC count from the cancer or from treatment for the cancer. Cancer may be in the bone marrow, causing fewer neutrophils to be made. The WBC count can also go down when cancer is treated with chemotherapy drugs, which slow bone marrow production of healthy WBCs. […] If you have any of the following symptoms, contact your health care provider: Fevers, chills, or sweats. Diarrhea that does not go away or is bloody. Severe nausea and vomiting. Being unable to eat or drink. Extreme weakness. Redness, swelling, or drainage from any place where you have an IV line inserted into your body. A new skin rash or blisters. Pain in your stomach area. A very bad headache or one that does not go away. A cough that is getting worse. Trouble breathing when you are at rest or when you are doing simple tasks. Burning when you urinate.

• #53 Low White Blood Cell Count and Leukemia | MyLeukemiaTeam

  https://www.myleukemiateam.com/resources/low-white-blood-cell-count-and-leukemia

  When someone has leukemia, their body overproduces WBCs. These extra leukemia cells dont function properly. Unlike their normal counterparts, they cant fight infection from viruses and bacteria, leaving the immune system vulnerable to attack. […] Certain types of leukemia are especially associated with a low WBC count. These include: Acute promyelocytic leukemia, Hairy cell leukemia, Acute megakaryoblastic leukemia. […] Any type of leukemia can eventually show low WBC counts due to bone marrow failure, a condition in which the bone marrow is unable to produce normal amounts of healthy blood cells. Additionally, a low WBC count could signal an infection. It can also mean the person is not getting good nutrition or enough iron. […] Both leukemia and some therapies to treat it can tax the immune system and reduce WBC levels. For example, chemotherapy is very effective at killing fast-growing cells, but it attacks both healthy blood cells and leukemia cells. Thats why low WBC counts are common during cancer treatment. A high blood cell count usually returns to normal on its own once treatment is over. […] Doctors monitor WBC counts in people with leukemia to track how the disease is responding to treatment or progressing.

• #54 Low White Blood Cell Count: 6 Common Causes – Tua Saúde

  https://www.tuasaude.com/en/low-white-blood-cell-count/

  A low white blood cell count can be caused by viral infections, medication side effects, nutritional deficiencies and, in some cases, problems such as sepsis, systemic lupus erythematosus or myelodysplasia. […] White blood cells are part of the immune system and levels are considered low when they are less than 4000 leukocytes per L of blood. This condition is also referred to as leukopenia. […] A low white blood cell count should be assessed by a hematologist, so that the underlying cause is identified and treated as necessary. […] A low white blood cell count can also be caused by the side effects of medications, like chemotherapy, corticosteroids, and some antibiotics or diuretics. These medication can affect the production of white blood cells in the bone marrow in some cases. […] A deficiency in nutrients such as vitamin B12 or folic acid can impair the production of red and white blood cells in the bone marrow.

• #55 Low White Blood Cell Count: 6 Common Causes – Tua Saúde

  https://www.tuasaude.com/en/low-white-blood-cell-count/

  A low white blood cell count can be caused by viral infections, medication side effects, nutritional deficiencies and, in some cases, problems such as sepsis, systemic lupus erythematosus or myelodysplasia. […] White blood cells are part of the immune system and levels are considered low when they are less than 4000 leukocytes per L of blood. This condition is also referred to as leukopenia. […] A low white blood cell count should be assessed by a hematologist, so that the underlying cause is identified and treated as necessary. […] A low white blood cell count can also be caused by the side effects of medications, like chemotherapy, corticosteroids, and some antibiotics or diuretics. These medication can affect the production of white blood cells in the bone marrow in some cases. […] A deficiency in nutrients such as vitamin B12 or folic acid can impair the production of red and white blood cells in the bone marrow.

• #56 Low White Blood Cell Count: 6 Common Causes – Tua Saúde

  https://www.tuasaude.com/en/low-white-blood-cell-count/

  A low white blood cell count can be caused by viral infections, medication side effects, nutritional deficiencies and, in some cases, problems such as sepsis, systemic lupus erythematosus or myelodysplasia. […] White blood cells are part of the immune system and levels are considered low when they are less than 4000 leukocytes per L of blood. This condition is also referred to as leukopenia. […] A low white blood cell count should be assessed by a hematologist, so that the underlying cause is identified and treated as necessary. […] A low white blood cell count can also be caused by the side effects of medications, like chemotherapy, corticosteroids, and some antibiotics or diuretics. These medication can affect the production of white blood cells in the bone marrow in some cases. […] A deficiency in nutrients such as vitamin B12 or folic acid can impair the production of red and white blood cells in the bone marrow.

• #57 Leukopenia – Wikipedia

  https://en.wikipedia.org/wiki/Leukopenia

  Leukopenia is a decrease in the number of leukocytes (WBC). Found in the blood, they are the white blood cells, and are the body’s primary defense against an infection. Thus the condition of leukopenia places individuals at increased risk of infection. […] Symptoms may include: skin or mouth ulcers, sore throat, cough, difficulty in breathing, light-headedness, fever, chills, body aches. […] Low white cell count may be due to acute viral infections, such as a cold or influenza. It has been associated with chemotherapy, radiation therapy, myelofibrosis, aplastic anemia (failure of white cell, red cell and platelet production), stem cell transplant, bone marrow transplant, HIV, AIDS, and steroid use. […] Other causes of low white blood cell count include systemic lupus erythematosus, Hodgkin’s lymphoma, some types of cancer, typhoid, malaria, tuberculosis, dengue, rickettsial infections, enlargement of the spleen, folate deficiencies, psittacosis, sepsis, Sjgren syndrome and Lyme disease. […] Chemotherapy targets cells that grow rapidly, such as tumors, but can also affect white blood cells, because they are characterized by bone marrow as rapid growing. A common side effect of cancer treatment is neutropenia, the lowering of neutrophils (a specific type of white blood cell).

• #58 Leukopenia – Wikipedia

  https://en.wikipedia.org/wiki/Leukopenia

  Leukopenia is a decrease in the number of leukocytes (WBC). Found in the blood, they are the white blood cells, and are the body’s primary defense against an infection. Thus the condition of leukopenia places individuals at increased risk of infection. […] Symptoms may include: skin or mouth ulcers, sore throat, cough, difficulty in breathing, light-headedness, fever, chills, body aches. […] Low white cell count may be due to acute viral infections, such as a cold or influenza. It has been associated with chemotherapy, radiation therapy, myelofibrosis, aplastic anemia (failure of white cell, red cell and platelet production), stem cell transplant, bone marrow transplant, HIV, AIDS, and steroid use. […] Other causes of low white blood cell count include systemic lupus erythematosus, Hodgkin’s lymphoma, some types of cancer, typhoid, malaria, tuberculosis, dengue, rickettsial infections, enlargement of the spleen, folate deficiencies, psittacosis, sepsis, Sjgren syndrome and Lyme disease. […] Chemotherapy targets cells that grow rapidly, such as tumors, but can also affect white blood cells, because they are characterized by bone marrow as rapid growing. A common side effect of cancer treatment is neutropenia, the lowering of neutrophils (a specific type of white blood cell).

• #59 Depressive symptoms and antidepressant use in relation to white blood cell count among postmenopausal women from the Women’s Health Initiative | Translational Psychiatry

  https://www.nature.com/articles/s41398-024-02872-5

  In conclusion, depressive symptoms and/or antidepressant use were cross-sectionally related to higher WBC counts among postmenopausal women. […] Women who exhibited depressive symptoms at enrollment and at 3-year follow-up visits experienced a faster decline in WBC count compared to women who did not experience depressive symptoms at either visit, implying that sustained depression may be linked to immune senescence over time.

• #60 WBC count Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/tests/wbc-count

  A low number of WBCs is called leukopenia. A count less than 4,500 cells per microliter (4.5 × 10^9/L) is below normal. […] A lower than normal WBC count may be due to: Bone marrow deficiency or failure (for example, due to infection, tumor, or abnormal scarring), Cancer treating drugs, or other medicines, Certain autoimmune disorders such as lupus (SLE), Disease of the liver or spleen, Radiation treatment for cancer, Certain viral illnesses, such as mononucleosis (mono), Cancers that damage the bone marrow, Very severe bacterial infections, Severe emotional or physical stress (such as from an injury or surgery), An ethnic/genetic trait (not uncommon in African Americans).

• #61 Leukopenia: Types, Symptoms, Causes, Treatment & More

  https://www.healthline.com/health/leukopenia

  Leukopenia is a low white blood cell count. It doesnt always cause symptoms, but it can lead to serious complications. […] You probably wont notice any signs of leukopenia. But if your WBC counts are very low, you may have signs of infection, including: a fever of 100.4F (38C) or above, chills, sweating, sore throat, cough or shortness of breath, an area of your body thats become red, swollen, or painful, an injury thats draining pus, mouth sores or white patches in your mouth, painful urination. […] Because leukopenia involves low levels of infection-fighting immune cells, it can cause some potentially serious complications if left untreated. Some of the complications of leukopenia include: needing to delay cancer treatment because of a mild infection, sepsis, a life threatening response by your body to an infection, septicemia, which is a serious bloodstream infection, recurrent or prolonged infections, premature death.

• #62 Chronic neutropenia | Immune Deficiency Foundation

  https://primaryimmune.org/understanding-primary-immunodeficiency/types-of-pi/chronic-neutropenia

  People with chronic neutropenia have low levels of white blood cells called neutrophils, and the condition is both a rare blood disorder and a rare type of primary immunodeficiency (PI). […] People with chronic neutropenia have a low number of neutrophils, the most common type of white blood cell, in their blood for longer than three months. […] The lower a persons neutrophil count, the greater their risk of infection. […] Symptoms associated with chronic neutropenia include recurring fevers, mouth sores (ulcers), inflammation of the tissues that surround and support the teeth (periodontitis), and inflammation of the sinuses (sinusitis), throat (pharyngitis), skin (dermatitis), and/or inner ear (otitis). […] Due to low levels of neutrophils, people with neutropenia may be more likely to get recurring bacterial infections that, in some people, result in life-threatening complications like sepsis.

• #63 Neutropenia | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/neutropenia

  Neutropenia is a rare disorder that causes children to have lower than normal levels of neutrophils, a type of white blood cell that destroys bacteria in the blood and helps protect against infections. Neutropenia can be a very serious condition. Without enough neutrophils, the body is susceptible to bacterial infections that can become life-threatening. […] Children with neutropenia tend to develop infections easily because their white blood cell count is too low to ward off bacteria. Most infections occur in the lungs, mouth, throat, ears, sinuses and skin. Some patients experience painful mouth ulcers and disease of the tissue surrounding the teeth, as well as infections of the urinary tract, colon, rectum or reproductive tract. […] Other symptoms include: Fever, Shaking chills, Sore throat, Cough or shortness of breath, Nasal congestion, Diarrhea or loose bowels, Burning during urination.

• #64 Chronic neutropenia | Immune Deficiency Foundation

  https://primaryimmune.org/understanding-primary-immunodeficiency/types-of-pi/chronic-neutropenia

  People with chronic neutropenia have low levels of white blood cells called neutrophils, and the condition is both a rare blood disorder and a rare type of primary immunodeficiency (PI). […] People with chronic neutropenia have a low number of neutrophils, the most common type of white blood cell, in their blood for longer than three months. […] The lower a persons neutrophil count, the greater their risk of infection. […] Symptoms associated with chronic neutropenia include recurring fevers, mouth sores (ulcers), inflammation of the tissues that surround and support the teeth (periodontitis), and inflammation of the sinuses (sinusitis), throat (pharyngitis), skin (dermatitis), and/or inner ear (otitis). […] Due to low levels of neutrophils, people with neutropenia may be more likely to get recurring bacterial infections that, in some people, result in life-threatening complications like sepsis.

• #65 Low White Blood Cell Count and Leukemia | MyLeukemiaTeam

  https://www.myleukemiateam.com/resources/low-white-blood-cell-count-and-leukemia

  When someone has leukemia, their body overproduces WBCs. These extra leukemia cells dont function properly. Unlike their normal counterparts, they cant fight infection from viruses and bacteria, leaving the immune system vulnerable to attack. […] Certain types of leukemia are especially associated with a low WBC count. These include: Acute promyelocytic leukemia, Hairy cell leukemia, Acute megakaryoblastic leukemia. […] Any type of leukemia can eventually show low WBC counts due to bone marrow failure, a condition in which the bone marrow is unable to produce normal amounts of healthy blood cells. Additionally, a low WBC count could signal an infection. It can also mean the person is not getting good nutrition or enough iron. […] Both leukemia and some therapies to treat it can tax the immune system and reduce WBC levels. For example, chemotherapy is very effective at killing fast-growing cells, but it attacks both healthy blood cells and leukemia cells. Thats why low WBC counts are common during cancer treatment. A high blood cell count usually returns to normal on its own once treatment is over. […] Doctors monitor WBC counts in people with leukemia to track how the disease is responding to treatment or progressing.

• #66 Treatment to remove white blood cells (leukapheresis) | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/acute-myeloid-leukaemia-aml/treating-aml/treatment-remove-white-blood-cells-leukapheresis

  You might have this treatment if you have a very high white blood cell count that may be causing symptoms. Some of the symptoms might include: shortness of breath, headaches, tiredness and feeling weak, changes to your vision, dizziness, confusion, bleeding. […] The treatment lowers the number of white blood cells straight away. This only lasts for a short time but it can help until chemotherapy has a chance to work. […] Symptoms of low calcium levels include: numbness and tingling – especially in your hands, feet and around your mouth, painful muscle spasms, feeling or being sick, low blood pressure. […] Your blood pressure and heart rate might drop suddenly making you pass out. You may go pale, sweat, feel sick, feel agitated or anxious. […] A low blood pressure can make you feel lightheaded or dizzy. Other symptoms might include feeling sick, blurred vision, feeling weak or confused.

• #67 Low White Blood Cell Count | Its Impact On Your Health | LLS

  https://www.lls.org/treatment/lab-and-imaging-tests/understanding-blood-counts

  Blood counts alone can’t determine whether you have a blood cancer, but they can alert your doctor if further testing is needed. […] If you have low white cell counts and develop a fever, you’ll know to contact your doctor promptly. […] Blood cancers can affect blood cell counts in a number of ways, either lowering or increasing measurements. If you’re currently receiving cancer treatment such as chemotherapy, drug therapy or radiation, your blood counts will be affected. Blood counts usually return to normal after treatment is complete.

• #68 White Blood Cell Count: Normal, High, and Low Counts

  https://www.healthline.com/health/wbc-count

  A normal white blood cell count is 5,000 to 10,000 for people assigned male at birth and 4,500 to 11,000 for people assigned female at birth. […] A white blood cell count can detect hidden infections within your body and alert doctors to undiagnosed medical conditions, such as autoimmune diseases, immune deficiencies, and blood disorders. […] If your test results are abnormal, it may mean that your numbers are higher or lower than the normal range. […] Low white blood cell count is referred to as leukopenia. […] Symptoms of a low WBC count can include fatigue, body aches, fever, chills, and headache. […] Having neutropenia may put you at an increased risk for infection. You may not have enough white blood cells to protect you from germs and bacteria.

• #69 Low White Blood Cell Count (Neutropenia) | OncoLink

  https://www.oncolink.org/support/side-effects/low-blood-counts/neutropenia

  A low neutrophil count (less than 1,000) is known as neutropenia. The lower the neutrophil count, the higher the risk of infection. […] An infection in a neutropenic patient is an emergency! If you notice any signs or symptoms of infection, you should call your provider right away – even if it is the middle of the night. […] Signs and symptoms of infection to look for: Check your temperature twice a day or any time you feel feverish (skin warm to the touch, chills, facial flushing). If your temperature is 100.4F (38.0C) or higher, call your provider right away. […] Shaking chills. […] Cough, sore throat, nasal congestion, or shortness of breath. […] Burning with urination or new lower back pain. […] Blood in the urine. […] Diarrhea (worsening) or change in the odor of your stool. […] Rash, redness, or swelling of the skin. […] Redness, soreness around central line catheter, feeding tube or a wound. […] Soreness or swelling in your mouth or throat, ulcers or white patches in your mouth, or a change in the color of your gums.

• #70 Leukopenia: Symptoms, Causes, and Treatment

  https://www.verywellhealth.com/leukopenia-5223575

  Leukopenia is when you have an abnormally low number of white blood cells (leukocytes). A low white blood cell count may or may not cause symptoms, but can result in serious health complications since you have fewer disease-fighting blood cells. […] Leukopenia may not present with any symptoms. However, underlying conditions that can cause leukopenia can be severe. […] Signs of conditions associated with leukopenia include symptoms of a frequent infection such as: Fever, chills, sweats, Fast heartbeat, Sore throat, Dizziness, Fatigue, Flu-like symptoms, Skin rashes, Sores that keep coming back (especially in the mouth), Pain in the joints, Burning when you urinate. […] While some infections can improve on their own, persistent leukopenia (specifically, neutropenia), can permit infections to recur and be prolonged and severe, which would require treatment. […] If you have leukopenia, its important to seek medical care to clarify the cause and treatment. Usually, identifying the underlying cause involves diagnostic testing before a treatment plan can be started.

• #71 Leukopenia (Low white blood cell count): Causes and more

  https://www.medicalnewstoday.com/articles/320299

  A person with leukopenia has a low number of white blood cells, or leukocytes, in their blood. A low white blood cell count may make a person more likely to contract an infection. […] A person may not show symptoms if they have a low white blood cell count. However, repeated infections may indicate leukopenia. The symptoms of infection include: fever, sweating, chills, toothache, sore throat, mouth ulcers that are difficult to heal, tiredness, flu-like symptoms, rash. […] Although leukopenia has no symptoms, it makes a person more susceptible to infections. As a result, a person should contact a doctor if they develop recurrent infections.

• #72 Low white blood cell count (neutropenia) | Canadian Cancer Society

  https://cancer.ca/en/treatments/side-effects/low-white-blood-cell-count

  Leukopenia and neutropenia do not cause any symptoms. People with cancer usually find out they have low white blood cell counts from a blood test or when they get an infection. An infection can start in almost any part of the body, but many occur in the skin, mucous membranes, digestive tract or respiratory tract. […] The most common signs and symptoms of an infection include: fever and chills, swelling and redness, mouth sores, red or white patches in the mouth, sore throat, severe cough or shortness of breath, pain or burning when urinating or foul-smelling urine, diarrhea, pain, redness or swelling of the rectal area, drainage, pus, redness or swelling from a cut, sore, incision, venous access device or drainage tube, unusual vaginal discharge or itching. […] Sometimes a fever is the only sign of infection, but a person can have an infection without having a fever or chills.

• #73 Low White Blood Cell Counts | Neutropenia | American Cancer Society

  https://www.cancer.org/cancer/managing-cancer/side-effects/low-blood-counts/neutropenia.html

  People with a low white blood cell count have a condition called neutropenia. Neutropenia itself doesn’t usually cause any signs or symptoms. If you are getting medicine or other treatments that often cause neutropenia, your cancer care team might check your white blood cell counts with blood tests. Managing neutropenia depends on the cause. But if you have signs of an infection and have a low WBC count, you might be started on a treatment before they know what is causing it. The nadir usually occurs about 7 to 10 days after getting chemo. This is when a person is most at risk for a severe infection. […] Call your cancer care team or get medical help if you have: A temperature over 100.4 F, Chills or sweating, New or worsening confusion, Dizziness, lightheadedness, or have been falling down, Chest pain, Trouble breathing even at rest.

• #74 Low White Blood Cell Count (Leukopenia): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/17706-low-white-blood-cell-count

  Leukopenia (low white blood cell count) happens when you have a lower-than-normal number of white blood cells. Specifically, you have fewer neutrophils than normal. Neutrophils are white blood cells that act as your immune systems first line of defense. Without enough white blood cells, youre more vulnerable to developing infections. […] Leukopenia doesnt have symptoms but it can cause infections that have the following symptoms: Fever and chills. Swelling and redness. Mouth sores. Red or white patches in your mouth. Sore throat. Severe cough or shortness of breath. Painful urination or pee that smells bad. Diarrhea. Cuts or sores that drain pus. Unusual vaginal discharge or itching. […] Your prognosis, or expected outcome, depends on why you have leukopenia. For example, you may have leukopenia because you have a viral infection. In that case, your white blood cell count should return to normal once youre over your infection. If your white blood cell count is low because youre receiving cancer treatment, your prognosis depends on your cancer diagnosis and treatment. […] Leukopenia increases your risk of developing infections, so you should contact your healthcare provider if you have leukopenia and think you may have an infection.

• #75 Leukopenia: Types, Symptoms, Causes, Treatment & More

  https://www.healthline.com/health/leukopenia

  Leukopenia is a low white blood cell count. It doesnt always cause symptoms, but it can lead to serious complications. […] You probably wont notice any signs of leukopenia. But if your WBC counts are very low, you may have signs of infection, including: a fever of 100.4F (38C) or above, chills, sweating, sore throat, cough or shortness of breath, an area of your body thats become red, swollen, or painful, an injury thats draining pus, mouth sores or white patches in your mouth, painful urination. […] Because leukopenia involves low levels of infection-fighting immune cells, it can cause some potentially serious complications if left untreated. Some of the complications of leukopenia include: needing to delay cancer treatment because of a mild infection, sepsis, a life threatening response by your body to an infection, septicemia, which is a serious bloodstream infection, recurrent or prolonged infections, premature death.

• #76 Low White Blood Cell Count (Neutropenia) | OncoLink

  https://www.oncolink.org/support/side-effects/low-blood-counts/neutropenia

  A low neutrophil count (less than 1,000) is known as neutropenia. The lower the neutrophil count, the higher the risk of infection. […] An infection in a neutropenic patient is an emergency! If you notice any signs or symptoms of infection, you should call your provider right away – even if it is the middle of the night. […] Signs and symptoms of infection to look for: Check your temperature twice a day or any time you feel feverish (skin warm to the touch, chills, facial flushing). If your temperature is 100.4F (38.0C) or higher, call your provider right away. […] Shaking chills. […] Cough, sore throat, nasal congestion, or shortness of breath. […] Burning with urination or new lower back pain. […] Blood in the urine. […] Diarrhea (worsening) or change in the odor of your stool. […] Rash, redness, or swelling of the skin. […] Redness, soreness around central line catheter, feeding tube or a wound. […] Soreness or swelling in your mouth or throat, ulcers or white patches in your mouth, or a change in the color of your gums.

• #77 Low White Blood Cell Count Tips

  https://www.virginiacancer.com/treatment-tips/low-white-blood-cell-count/

  Neutropenia is a low level of white blood cells. […] Since white blood cells play an important role in preventing infection, any time your white blood cell count drops, you are at higher risk of getting an infection. […] Your white blood cell count will be checked periodically throughout the course of your treatments. Any time that your white blood cell count drops below 1,000 per mm3, you will be considered neutropenic. […] If your white blood cell count drops to 1,000 per mm3 or below, you are considered to be neutropenic. Until your count rises, it will be necessary for you to take additional measures to further decrease your risk for infection. […] Call your doctor if you have any one or more of the following: oral temperature above 100.5o degrees, chills or sweats […] One growth factor stimulates the growth of white blood cells and is used frequently with cancer patients, especially those receiving chemotherapy and radiation therapy. By increasing your body’s production of white blood cells, this growth factor can decrease your risk of developing an infection. […] If you require IV medications, accommodations can be made for you to receive them in our office or possibly at home. Some patients require admission to the hospital in order to effectively treat their infection.

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