Materiały źródłowe

• #1 CE Activity | IgA Nephropathy (Berger Disease) | NPs

  https://www.statpearls.com/nursepractitioner/ce/activity/95477

  Immunoglobulin A (IgA) nephropathy, or IgAN, also known as Berger disease, is one of the leading causes of glomerulonephritis and renal failure. This disease is a prevalent form of glomerulonephritis characterized by the deposition of IgA in the glomerular basement membrane. Immune-mediated damage to the basement membrane results in hematuria, proteinuria, and renal insufficiency. Pathologically, a spectrum of glomerular lesions may be seen, with mesangial proliferation and prominent IgA deposition being the most commonly observed change. […] Management entails inducing remission and preventing complications by addressing proteinuria, estimated glomerular filtration rate (GFR), blood pressure, and histological findings, while treatment strategies aim to mitigate immune reactions, reduce IgA deposition, and slow renal damage progression. This activity comprehensively reviews the etiology, pathogenesis, evaluation, and management of IgAN while also explaining the role of the interprofessional healthcare team in evaluating and treating patients with this condition effectively.

• #2 CE Activity | IgA Nephropathy (Berger Disease) | Nurses

  https://www.statpearls.com/nurse/ce/activity/102258

  Immunoglobulin A (IgA) nephropathy, or IgAN, also known as Berger disease, is one of the leading causes of glomerulonephritis and renal failure. This disease is a prevalent form of glomerulonephritis characterized by the deposition of IgA in the glomerular basement membrane. Immune-mediated damage to the basement membrane results in hematuria, proteinuria, and renal insufficiency. Pathologically, a spectrum of glomerular lesions may be seen, with mesangial proliferation and prominent IgA deposition being the most commonly observed change. […] Management entails inducing remission and preventing complications by addressing proteinuria, estimated glomerular filtration rate (GFR), blood pressure, and histological findings, while treatment strategies aim to mitigate immune reactions, reduce IgA deposition, and slow renal damage progression. This activity comprehensively reviews the etiology, pathogenesis, evaluation, and management of IgAN while also explaining the role of the interprofessional healthcare team in evaluating and treating patients with this condition effectively.

• #3 IgA Nephropathy (Berger’s Disease) – DaVita

  http://www.davita.com/education/kidney-disease/related-diseases/iga-nephropathy-bergers-disease

  In 1968, French nephrologist Dr. Jean Berger first described immunoglobulin A (IgA) nephropathy. Sometimes referred to as Bergers disease, IgA nephropathy is a kidney disease that causes the kidneys to become inflamed. […] After diabetes and high blood pressure, IgA nephropathy is the third leading cause of chronic kidney disease (CKD) in the United States. […] IgA nephropathy cannot be prevented and has no cure. Some people are able to live with the disease without many complications. But half of the people who do get IgA nephropathy may progress to ESRD. Your doctor will work with you to help treat this condition and may recommend: […] Talk with your doctor about getting tested for IgA nephropathy and things you should and should not do if you’re diagnosed with the disease.

• #4 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  IgA Nephropathy (IgAN), in past sometimes known as Bergers Disease, is an inflammatory disease of the kidney, the most common primary glomerulonephritis worldwide as well a leading cause of End-Stage Kidney Disease (ESKD). […] The disease is often detected accidentally. Proteinuria (protein in the urine) and/or haematuria (blood in the urine) are found during routine check-ups. […] Even if most of affected children have a mild course of the disease, up to 30-40% of them may already present advanced chronic lesions that require specialised treatment at the time of diagnosis. […] Tous les patients atteints d’IgAN doivent subir des examens réguliers, en particulier des analyses d’urine, des analyses de sang et une surveillance de la tension artérielle. Une hospitalisation peut s’avérer nécessaire, en particulier au moment du diagnostic, par exemple lorsqu’une biopsie rénale est pratiquée, ou en cas d’altération significative de l’état clinique.

• #5 Furthering Managed Care Through Advances in IgA Nephropathy Therapy

  https://www.managedhealthcareexecutive.com/view/furthering-managed-care-through-advances-in-iga-nephropathy-therapy

  Immunoglobulin A nephropathy (IgAN), also known as Berger disease, is an autoimmune condition and the most common type of primary glomerulonephritis worldwide. IgAN is characterized by the accumulation of IgA complexes in the kidneys glomeruli, which results in progressive damage that can lead to chronic kidney disease (CKD). The ongoing glomerular damage disrupts the filtration barrier; over time, scarring of the nephrons occurs, culminating in end-stage renal disease (ESRD). Alarmingly, 40% to 53% of patients progress to ESRD within two decades of diagnosis. This severe progression necessitates interventions such as dialysis or kidney transplantation; either of these interventions significantly impacts the patients quality of life (QOL) and imposes substantial economic burdens. […] The primary aim of IgAN treatment is to prevent or delay progression to ESRD and preserve kidney function. In its 2021 clinical practice guideline for the management of glomerular diseases, Kidney Disease: Improving Global Outcomes (KDIGO) issued guidance for the management of IgAN absent any FDA-approved treatments. Recent advancements in understanding the pathogenesis of IgAN as an immune-mediated disease and the acceptance of surrogate outcomes for accelerated drug approval have led to a rapid increase in clinical trials exploring new therapeutic strategies that target specific disease pathways.

• #6 Berger’s Disease (IgA Nephropathy) – Nephritic Syndromes – Pathology for Medicine

  https://www.picmonic.com/pathways/medicine/courses/standard/pathology-196/nephritic-syndromes-39439/bergers-disease-iga-nephropathy_393

  Berger’s disease is a nephritic kidney disease, also known as IgA glomerulopathy, that is characterized by the presence of IgA deposits in the mesangium of the kidneys, which can be detected via immunofluorescence microscopy and light microscopy. […] IgA nephropathy is an alternative name for Berger’s disease and draws from the increased synthesis of immunoglobulin A involved in the pathogenesis. […] In patients with IgA nephropathy, levels of plasma IgA are increased and there is prominent deposition of IgA immune complexes in the mesangium. […] Berger’s disease is a common cause of recurrent gross or microscopic hematuria and is the most common cause of nephritic syndrome in the developed world. […] Berger’s disease commonly presents as gross hematuria after an upper respiratory infection or less commonly an acute gastroenteritis.

• #7 IgA Nephropathy (IgAN) | National Kidney Foundation

  https://www.kidney.org/kidney-topics/iga-nephropathy

  IgA nephropathy (IgAN) is a type of kidney disease where antibodies build up in your kidneys and cause damage to your glomeruli (small filters inside your kidneys). […] IgAN is also known as Bergers disease. […] Healthy kidneys keep blood cells and albumin (protein) from getting into the urine. So, one of the earliest signs of kidney damage from IgAN is the leaking of blood and/or protein (albumin) into your urine. Without treatment, this can get worse over time and lead to complications. […] There is no cure for IgAN. So, treatment is focused on managing symptoms, managing your blood pressure, and slowing the kidney disease process. […] Lifestyle recommendations include stopping smoking, losing weight through a balanced diet and physical activity, exercising regularly, and limiting sodium intake.

• #8 Tracking IgA nephropathy episodes important to improve patient comfort | UCI Health | Orange County, CA

  https://www.ucihealth.org/news/2024/12/iga-nephropathy-swelling

  When the protein immunoglobulin A builds up in the kidneys, it results in IgA nephropathy (IgAN), a progressive condition that can cause painful inflammation and swelling. […] Also known as Berger disease, its symptoms include high blood pressure, urine color changes and swelling around the eyes, especially in the morning. […] The mainstay of treatment involves medications that address both blood pressure and issues directly related to IgAN, but there are some helpful strategies that can reduce swelling in a short-term way to make you more comfortable. […] Chang adds that tracking swelling episodes can give your physician valuable information about the frequency of episodes and whether the IgAN is progressing.

• #9 What is IgA Nephropathy? | Duly Health and Care

  https://www.dulyhealthandcare.com/health-topic/what-is-iga-nephropathy

  Nephrology […] This abnormal buildup of IgA in the kidneys is known as IgA nephropathy (formerly called Bergers Disease). […] Over time, the accumulation of IgA in the kidneys can cause inflammation and make it more difficult for your kidney to filter waste and in some cases, lead to kidney damage. […] IgA nephropathy causes an increase of blood and protein in the urine. […] As the disease progresses and kidney damage worsens, additional symptoms may include: Pain along the side of your back below your ribs, Swelling in the hands and feet, Elevated blood pressure. […] While routine tests can confirm the presence of protein or blood in the urine, in order to confirm an IgA nephropathy diagnosis, your doctor will need to perform a kidney biopsy. […] Some additional complications of IgA neuropathy can include: High blood pressure, High Cholesterol, Kidney failure, Chronic kidney disease.

• #10 What is IgA Nephropathy? | Duly Health and Care

  https://www.dulyhealthandcare.com/health-topic/what-is-iga-nephropathy

  Nephrology […] This abnormal buildup of IgA in the kidneys is known as IgA nephropathy (formerly called Bergers Disease). […] Over time, the accumulation of IgA in the kidneys can cause inflammation and make it more difficult for your kidney to filter waste and in some cases, lead to kidney damage. […] IgA nephropathy causes an increase of blood and protein in the urine. […] As the disease progresses and kidney damage worsens, additional symptoms may include: Pain along the side of your back below your ribs, Swelling in the hands and feet, Elevated blood pressure. […] While routine tests can confirm the presence of protein or blood in the urine, in order to confirm an IgA nephropathy diagnosis, your doctor will need to perform a kidney biopsy. […] Some additional complications of IgA neuropathy can include: High blood pressure, High Cholesterol, Kidney failure, Chronic kidney disease.

• #11 New study sheds light on incidence of IgA nephropathy – Kaiser Permanente Department of Research & Evaluation

  https://www.kp-scalresearch.org/new-study-sheds-light-on-incidence-of-iga-nephropathy/

  IgA nephropathy, also known as Bergers disease, is a chronic kidney disease that occurs when the immune system produces abnormally formed antibodies that build up in the kidneys. […] In addition to providing a more solid estimate for the overall incidence of IgA nephropathy and describing the racial/ethnic groups most at risk, our study emphasized the importance of early diagnosis, Dr. Sim said. IgA nephropathy is a progressive disease and first manifests with isolated blood in the urine or mild proteinuria. We observed that our IgA nephropathy population was diagnosed at advanced disease as evidenced by their kidney function and the amount of proteinuria at biopsy. Earlier diagnosis and treatment can alter the course of the disease and delay or prevent kidney failure.

• #12 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  IgA Nephropathy (IgAN), in past sometimes known as Bergers Disease, is an inflammatory disease of the kidney, the most common primary glomerulonephritis worldwide as well a leading cause of End-Stage Kidney Disease (ESKD). […] The disease is often detected accidentally. Proteinuria (protein in the urine) and/or haematuria (blood in the urine) are found during routine check-ups. […] Even if most of affected children have a mild course of the disease, up to 30-40% of them may already present advanced chronic lesions that require specialised treatment at the time of diagnosis. […] Tous les patients atteints d’IgAN doivent subir des examens réguliers, en particulier des analyses d’urine, des analyses de sang et une surveillance de la tension artérielle. Une hospitalisation peut s’avérer nécessaire, en particulier au moment du diagnostic, par exemple lorsqu’une biopsie rénale est pratiquée, ou en cas d’altération significative de l’état clinique.

• #13 IgA nephropathy (Berger disease) – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/iga-nephropathy/diagnosis-treatment/drc-20352274

  IgA nephropathy is often found after you notice blood in your urine. […] Our caring team of Mayo Clinic experts can help you with your iga nephropathy (berger disease)-related health concerns. […] There’s no cure for IgA nephropathy. […] For others, medicines can slow the disease from becoming worse and help manage symptoms. […] The main goal of treatment is to keep you from needing dialysis or a kidney transplant. […] To help keep your kidneys healthier: Take steps to lower your blood pressure. […] If you have questions or you need guidance, talk with a member of your health care team. […] You’re likely to start by seeing your primary doctor. But you might be referred to a doctor who is trained to treat kidney disorders, called a nephrologist. […] Ask your doctor if you should cut back on protein. This may help slow IgA nephropathy from becoming worse and protect your kidneys.

• #14 IgA Nephropathy – NIDDK

  https://www.niddk.nih.gov/health-information/kidney-disease/iga-nephropathy

  IgA nephropathy is also known as Bergers disease. […] Health care professionals in most cases, kidney experts called nephrologists treat IgA nephropathy with medicines that help reduce blood pressure and loss of protein in the urine. […] Health care professionals treat IgA nephropathy with medicines and lifestyle changes. […] In some cases, your health care professional may also prescribe immunosuppressants, including corticosteroids. […] Although researchers have not yet found a cure for IgA nephropathy, treatment can help prevent or delay damage to your kidneys. […] If you have IgA nephropathy, limiting the amount of salt in your diet may help reduce swelling and lower blood pressure. Your health care professional may suggest other changes to your diet based on your symptoms, lab test results, and personal needs.

• #15 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  The choice of the therapeutic approach varies according to the individual’s condition and in particular the estimated risk of progression to end-stage kidney disease (ESKD). […] Essential at any stage of the disease are changes in lifestyle, consisting of: Increasing regular physical activity focusing on endurance sports (avoiding high intensity sports (e.g. heavy weight lifting), Weight control for prevention/reduction of obesity, Healthy diet and correction of possible lipid disorders, No smoking (smoking increases the risk of dialysis 5-10-fold!), Low salt intake, Avoidance of using so-called non-steroid antiphlogistic drugs as pain killers, e.g. diclofenac, ibuprofen, indomethacine (aspirin, paracetamol and opiates are safe as far as the kidneys are concerned). […] Immunosuppressive therapy, e.g. steroid therapy (corticosteroids): steroids are usually administered over several months (four-six months); other immunosuppressive drugs are only used in most severe cases.

• #16 IgA Nephropathy (Berger Disease): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/5990-iga-nephropathy

  IgA nephropathy, or Bergers disease, is a kidney disease in which IgA antibodies build up abnormally. Over time, it leads to kidney damage or kidney failure. Symptoms include blood in your pee, swelling and flank pain. Medications can slow the diseases progress. But some people may need dialysis or a kidney transplant. […] Treatment can slow the progress of the disease and prevent ESRD. If you have IgA nephropathy, your healthcare provider will probably refer you to a nephrologist, a kidney disease specialist. […] Treatment for IgA nephropathy includes medication to: Regulate blood pressure with angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), or other medicines; Remove extra fluid with a diuretic; Control your immune system to lower kidney inflammation with prescribed steroids such as prednisone or cyclophosphamide, a different medicine; Lower your cholesterol levels with medications such as statins.

• #17 IgA Nephropathy (Berger’s Disease) | Doctor

  https://patient.info/doctor/iga-nephropathy-bergers-disease-pro

  IgA nephropathy is the most common primary glomerular disease. It has a worldwide incidence of 2.5 per 100,000 with higher prevalence noted in Eastern and Pacific Asian countries. It is rare in African countries. In European and American patients there is a 2:1 male: female ratio. […] No specific therapy is available for IgAN so the aim is supportive management. Lowering blood pressure and renin-angiotensin system inhibition remain the cornerstone of management. Patients should be advised to follow a low-salt diet. […] Patients with haematuria but no albuminuria need monitoring by urinalysis, kidney function and checking blood pressure. […] Angiotensin-converting enzyme (ACE) inhibitors/angiotensin-II receptor antagonists (AIIRAs): Hypertension needs early and aggressive treatment, titrating up to maximum tolerated dose. ACE inhibitors or AIIRAs are the drugs of choice. They protect kidney function and are also beneficial when blood pressure is normal.

• #18 Furthering Managed Care Through Advances in IgA Nephropathy Therapy

  https://www.managedhealthcareexecutive.com/view/furthering-managed-care-through-advances-in-iga-nephropathy-therapy

  With no FDA-approved treatments at the time of its writing, the 2021 KDIGO guidelines underscore strategies not based upon immunosuppression. Aiming to slow disease progression, this supportive care is centered upon lifestyle modification (e.g., exercise, smoking cessation, weight loss, reduction of sodium in the diet), blood pressure control and renin-angiotensin system (RAS) inhibition. Cardiovascular risk should be addressed, and all patients should have their blood pressure managed, with the KDIGO work group suggesting a target systolic blood pressure of less than 120 mm Hg in most patients. RAS inhibition should be provided to all patients with IgAN who have proteinuria exceeding 0.5 g/day regardless of hypertension status; therapy with either an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker should be used.

• #19 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  The choice of the therapeutic approach varies according to the individual’s condition and in particular the estimated risk of progression to end-stage kidney disease (ESKD). […] Essential at any stage of the disease are changes in lifestyle, consisting of: Increasing regular physical activity focusing on endurance sports (avoiding high intensity sports (e.g. heavy weight lifting), Weight control for prevention/reduction of obesity, Healthy diet and correction of possible lipid disorders, No smoking (smoking increases the risk of dialysis 5-10-fold!), Low salt intake, Avoidance of using so-called non-steroid antiphlogistic drugs as pain killers, e.g. diclofenac, ibuprofen, indomethacine (aspirin, paracetamol and opiates are safe as far as the kidneys are concerned). […] Immunosuppressive therapy, e.g. steroid therapy (corticosteroids): steroids are usually administered over several months (four-six months); other immunosuppressive drugs are only used in most severe cases.

• #20 IgA Nephropathy Treatment & Management: Approach Considerations, Medical Care, Diet

  https://emedicine.medscape.com/article/239927-treatment

  The role of direct renin inhibitors and mineralocorticoid receptor antagonists have not been evaluated in a randomized controlled trial. If GFR 25 mL/min/1.73 m2 and UPCR is 0.6 g/day there is a benefit to treatment. […] Angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) are the preferred agents for lowering blood pressure and decreasing proteinuria. […] Corticosteroid regimens studied have included the following: Intravenous methylprednisolone, 1 g/day for 3 consecutive days at months 1, 3, and 5; plus oral prednisone for 6 months at 0.5 mg/kg every other day. […] Guidelines for IgA nephropathy from Kidney Disease: Improving Global Outcomes (KDIGO) suggest that a 6-month course of corticosteroid therapy may be given to patients who have persistent proteinuria 1 g/d despite 36 months of optimized supportive care (including ACEI or ARB treatment and blood pressure control), and a glomerular filtration rate (GFR) 50 mL/min/1.73m2.

• #21 IgA Nephropathy (Berger’s Disease) | Doctor

  https://patient.info/doctor/iga-nephropathy-bergers-disease-pro

  Steroid therapy is associated with a decrease of proteinuria and with a statistically significant reduction of the risk of ESKD. […] The National Institute for Health and Care Excellence (NICE) has recommended targeted-release budesonide as an option for treating primary IgAN when there is a risk of rapid disease progression in adults with a urine protein-to-creatinine ratio of 1.5 g/g or more. […] There is evidence that tonsillectomy slows down the progression of IgA nephropathy. However, it is not currently recommended in guidelines, unless otherwise indicated due to recurrent infection.

• #22 IgA Nephropathy (Berger’s Disease) Treatment Options

  https://www.healthline.com/health/treatment-options-for-iga-nephropathy

  Doctors may prescribe a diuretic together with these medications to make them more effective. […] Another non-immunosuppressive medication is sparsentan, an endothelin and angiotensin II receptor antagonist. It lowers levels of protein in the urine in people with IgA nephropathy whose condition may progress quickly. […] Immunosuppressive medications for IgA nephropathy include: cyclophosphamide and corticosteroids, such as prednisone. […] Budesonide is another corticosteroid a doctor may prescribe for IgA nephropathy. It helps decrease inflammation in the kidneys and reduce levels of protein in the urine in people whose condition may progress quickly. […] A healthcare professional may recommend a variety of lifestyle changes to help you manage IgA nephropathy. […] These dietary modifications may include: Limiting the amount of sodium in your diet, following a diet that is low in saturated fats and cholesterol, and shifting toward a plant-based diet.

• #23 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  The choice of the therapeutic approach varies according to the individual’s condition and in particular the estimated risk of progression to end-stage kidney disease (ESKD). […] Essential at any stage of the disease are changes in lifestyle, consisting of: Increasing regular physical activity focusing on endurance sports (avoiding high intensity sports (e.g. heavy weight lifting), Weight control for prevention/reduction of obesity, Healthy diet and correction of possible lipid disorders, No smoking (smoking increases the risk of dialysis 5-10-fold!), Low salt intake, Avoidance of using so-called non-steroid antiphlogistic drugs as pain killers, e.g. diclofenac, ibuprofen, indomethacine (aspirin, paracetamol and opiates are safe as far as the kidneys are concerned). […] Immunosuppressive therapy, e.g. steroid therapy (corticosteroids): steroids are usually administered over several months (four-six months); other immunosuppressive drugs are only used in most severe cases.

• #24 IgA Nephropathy Treatment & Management: Approach Considerations, Medical Care, Diet

  https://emedicine.medscape.com/article/239927-treatment

  The KDIGO guidelines suggest not treating with corticosteroids combined with cyclophosphamide or azathioprine unless the patient has crescentic IgA nephropathy with rapidly deteriorating kidney function. Use of mycophenolate mofetil has been controversial, as studies have been small in size and studies have reported negative results. The KDIGO guidelines do not recommend use of mycophenolate mofetil. […] The STOP-IgAN authors note that the study results do not apply to patients who have proteinuria 3.5 g/day, as such patients have a very high risk of progression and have been reported to have a particularly good response to corticosteroids. Thus, use of immunosuppression should be considered only for patients with active disease and rapid progression. […] A low-antigen diet, which consists of restricting dietary gluten and avoiding meats and dairy products, has been recommended to decrease mucosal antigen exposure. However, it has not been shown to preserve kidney function.

• #25 IgA nephropathy | Kidney Care UK

  https://kidneycareuk.org/kidney-disease-information/kidney-conditions/iga-nephropathy/

  IgAN is also known as Bergers disease. […] If treatment is needed, the initial aim is to protect kidney function by lowering blood pressure via lifestyle measures such as losing weight, stopping smoking and reducing salt in the diet. […] Blood pressure medication may also be prescribed, such as angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs). […] If you have protein in the urine, you may be prescribed blood pressure medication, even if you do not have high blood pressure. […] SGLT2 (sodium-glucose co-transporter 2) inhibitors, are also often prescribed to slow the progression of IgAN. […] If such supportive treatment methods do not help, immunosuppressants such as steroids may be prescribed, to dampen the immune system. […] Targeted-release budesonide can help to slow the decline of kidney function by reducing the amount of the IgA protein that builds up in the kidneys. […] In most people, kidney function deteriorates slowly. Around 1 in 3 people with IgAN will require dialysis and/or transplant within around 20 years.

• #26 IgA Nephropathy Treatment & Management: Approach Considerations, Medical Care, Diet

  https://emedicine.medscape.com/article/239927-treatment

  Because the clinical presentation and prognosis in IgA nephropathy varies widely, treatment must be individualized. All patients should be given supportive therapy to control hypertension and proteinuria, including renin-angiotensin system blockade and dietary sodium restriction. Tonsillectomy is appropriate only for patients with recurrent tonsillar infections. […] Control of proteinuria is prudent, since there is a mostly linear association between the severity of proteinuria and decline in estimated glomerular filtration rate (GFR). Use of immunosuppression should be determined by considering the rate of progression, comorbidities, and whether alarming features are present on biopsy. However, immunosuppression has become controversial. Currently, corticosteroids are the option with the most convincing evidence to support their use, but if used, they should be administered only to carefully selected patients, and preferably should not be given for more than 6 months. Sodiumglucose transporter 2 (SGLT2) inhibitors, which have an established role in chronic kidney disease generally, have also demonstrated benefit in IgA nephropathy.

• #27 Dapagliflozin Shown to Be Safe, Effective in Patients With CKD

  https://www.ajmc.com/view/dapagliflozin-shown-to-be-safe-effective-in-patients-with-ckd

  Dapagliflozin substantially slowed the progression of chronic kidney disease (CKD) in patients with immunoglobulin A nephropathy, according to a new study. […] Treatment with dapagliflozin substantially reduced the risk of chronic kidney disease progression in patients with immunoglobulin A (IgA) nephropathy when added to renin-angiotensin-system blockade, according to a new study published in Kidney International. […] The predominant strategy is to use supportive measures, including renin-angiotensin-aldosterone blockade. […] Immunosuppressive therapy is controversial and usually reserved for patients who don’t respond to supportive measures. […] This prespecified analysis of the DAPA-CKD study demonstrates that in patients with IgA nephropathy, when added to ACEi/ARB therapy, the authors concluded, dapagliflozin significantly and substantially reduces the risk of CKD progression with a favorable safety profile.

• #28 IgA Nephropathy (Berger’s Disease) Treatment Options

  https://www.healthline.com/health/treatment-options-for-iga-nephropathy

  Doctors may prescribe a diuretic together with these medications to make them more effective. […] Another non-immunosuppressive medication is sparsentan, an endothelin and angiotensin II receptor antagonist. It lowers levels of protein in the urine in people with IgA nephropathy whose condition may progress quickly. […] Immunosuppressive medications for IgA nephropathy include: cyclophosphamide and corticosteroids, such as prednisone. […] Budesonide is another corticosteroid a doctor may prescribe for IgA nephropathy. It helps decrease inflammation in the kidneys and reduce levels of protein in the urine in people whose condition may progress quickly. […] A healthcare professional may recommend a variety of lifestyle changes to help you manage IgA nephropathy. […] These dietary modifications may include: Limiting the amount of sodium in your diet, following a diet that is low in saturated fats and cholesterol, and shifting toward a plant-based diet.

• #29 IgA Nephropathy (Berger Disease): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/5990-iga-nephropathy

  IgA nephropathy, or Bergers disease, is a kidney disease in which IgA antibodies build up abnormally. Over time, it leads to kidney damage or kidney failure. Symptoms include blood in your pee, swelling and flank pain. Medications can slow the diseases progress. But some people may need dialysis or a kidney transplant. […] Treatment can slow the progress of the disease and prevent ESRD. If you have IgA nephropathy, your healthcare provider will probably refer you to a nephrologist, a kidney disease specialist. […] Treatment for IgA nephropathy includes medication to: Regulate blood pressure with angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), or other medicines; Remove extra fluid with a diuretic; Control your immune system to lower kidney inflammation with prescribed steroids such as prednisone or cyclophosphamide, a different medicine; Lower your cholesterol levels with medications such as statins.

• #30 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  The choice of the therapeutic approach varies according to the individual’s condition and in particular the estimated risk of progression to end-stage kidney disease (ESKD). […] Essential at any stage of the disease are changes in lifestyle, consisting of: Increasing regular physical activity focusing on endurance sports (avoiding high intensity sports (e.g. heavy weight lifting), Weight control for prevention/reduction of obesity, Healthy diet and correction of possible lipid disorders, No smoking (smoking increases the risk of dialysis 5-10-fold!), Low salt intake, Avoidance of using so-called non-steroid antiphlogistic drugs as pain killers, e.g. diclofenac, ibuprofen, indomethacine (aspirin, paracetamol and opiates are safe as far as the kidneys are concerned). […] Immunosuppressive therapy, e.g. steroid therapy (corticosteroids): steroids are usually administered over several months (four-six months); other immunosuppressive drugs are only used in most severe cases.

• #31 IgA Nephropathy: Stages, Symptoms, Diagnosis, Treatment

  https://www.health.com/iga-nephropathy-stages-8702883

  In these early stages, your provider will want to focus on avoiding complications from IgA nephropathy, such as high blood pressure or diabetes, and may suggest the following: Maintaining healthy blood pressure and blood sugar levels, Taking medications (like statins) to help protect against heart disease and further kidney damage, Considering the pros and cons of medications that target the immune system directly (like corticosteroids) before too much kidney damage has occurred, Recommended lifestyle changes, like eating a kidney-friendly diet and avoiding smoking. […] Your healthcare provider should pursue an aggressive treatment strategy to prevent this from occurring. […] Follow your treatment plan closely and discuss it with your healthcare provider if you have any questions or concerns. Research shows that prescribed medications for IgA nephropathy help control blood pressure and reduce the amount of protein in urine, ultimately slowing or preventing damage to the kidneys. […] Managing your stress levels, particularly through mindfulness techniques like yoga and meditation, has been shown to help improve depression symptoms, heart and lung function, and overall quality of life in people with IgA nephropathy and chronic kidney disease.

• #32 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  The choice of the therapeutic approach varies according to the individual’s condition and in particular the estimated risk of progression to end-stage kidney disease (ESKD). […] Essential at any stage of the disease are changes in lifestyle, consisting of: Increasing regular physical activity focusing on endurance sports (avoiding high intensity sports (e.g. heavy weight lifting), Weight control for prevention/reduction of obesity, Healthy diet and correction of possible lipid disorders, No smoking (smoking increases the risk of dialysis 5-10-fold!), Low salt intake, Avoidance of using so-called non-steroid antiphlogistic drugs as pain killers, e.g. diclofenac, ibuprofen, indomethacine (aspirin, paracetamol and opiates are safe as far as the kidneys are concerned). […] Immunosuppressive therapy, e.g. steroid therapy (corticosteroids): steroids are usually administered over several months (four-six months); other immunosuppressive drugs are only used in most severe cases.

• #33 IgA nephropathy (Berger disease) | Beacon Health System

  https://www.beaconhealthsystem.org/library/diseases-and-conditions/iga-nephropathy-berger-disease?content_id=CON-20166955

  The main goal of treatment is to keep you from needing dialysis or a kidney transplant. But either of those treatments can be lifesaving if your kidneys stop working well enough on their own. […] To help keep your kidneys healthier: Take steps to lower your blood pressure. This can help slow kidney damage from IgA nephropathy. Start with some healthy lifestyle changes. Limit how much sodium and fat you eat. Lose any extra weight. Get regular exercise. And if you drink alcohol, do so in moderation. Also take your blood pressure medicines as prescribed. Keep track of your blood pressure at home. If your health care team asks you to do this, write down each blood pressure reading. Then bring the record with you to checkups. Eat less protein. Ask your doctor if you should cut back on protein. This may help slow IgA nephropathy from becoming worse and protect your kidneys.

• #34 What is IgA Nephropathy? – Immunoglobulin A [Berger’s Disease]

  https://igan.org/faq/

  Your doctor may want to put you on a low-salt diet to minimize stress of the kidneys and prevent excess fluid retention that would strain your heart. […] The possibility of recurrent IgAN should not discourage patients from having a transplant, but they should be aware that a transplant is not a cure for the disease, merely a replacement organ.

• #35 IgA Nephropathy Treatment: Medication, Surgery, & More

  https://www.health.com/iga-nephropathy-treatment-8702877

  Your healthcare provider may recommend one or more of the following medications: Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs): Control hypertension (high blood pressure) and slow down kidney damage by reducing the amount of protein that passes into the urine through damaged kidneys. […] If Berger’s disease worsens and causes kidney failure, there are a few additional treatment options that your provider can use to help reduce symptoms. These include: Dialysis: This procedure uses a filtering machine to manually remove toxins and extra fluid from the blood when the kidneys can no longer effectively perform that function. […] There are several lifestyle adjustments that your healthcare provider may suggest to help support your treatment plan. This typically includes recommendations such as the following: Eat a nutritious diet: Includes foods low in sodium, saturated fat, and cholesterol to reduce swelling and lower blood pressure.

• #36 IgA nephropathy (Berger disease) – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/iga-nephropathy/diagnosis-treatment/drc-20352274

  IgA nephropathy is often found after you notice blood in your urine. […] Our caring team of Mayo Clinic experts can help you with your iga nephropathy (berger disease)-related health concerns. […] There’s no cure for IgA nephropathy. […] For others, medicines can slow the disease from becoming worse and help manage symptoms. […] The main goal of treatment is to keep you from needing dialysis or a kidney transplant. […] To help keep your kidneys healthier: Take steps to lower your blood pressure. […] If you have questions or you need guidance, talk with a member of your health care team. […] You’re likely to start by seeing your primary doctor. But you might be referred to a doctor who is trained to treat kidney disorders, called a nephrologist. […] Ask your doctor if you should cut back on protein. This may help slow IgA nephropathy from becoming worse and protect your kidneys.

• #37 IgA nephropathy (Berger disease) | Beacon Health System

  https://www.beaconhealthsystem.org/library/diseases-and-conditions/iga-nephropathy-berger-disease?content_id=CON-20166955

  The main goal of treatment is to keep you from needing dialysis or a kidney transplant. But either of those treatments can be lifesaving if your kidneys stop working well enough on their own. […] To help keep your kidneys healthier: Take steps to lower your blood pressure. This can help slow kidney damage from IgA nephropathy. Start with some healthy lifestyle changes. Limit how much sodium and fat you eat. Lose any extra weight. Get regular exercise. And if you drink alcohol, do so in moderation. Also take your blood pressure medicines as prescribed. Keep track of your blood pressure at home. If your health care team asks you to do this, write down each blood pressure reading. Then bring the record with you to checkups. Eat less protein. Ask your doctor if you should cut back on protein. This may help slow IgA nephropathy from becoming worse and protect your kidneys.

• #38 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  The choice of the therapeutic approach varies according to the individual’s condition and in particular the estimated risk of progression to end-stage kidney disease (ESKD). […] Essential at any stage of the disease are changes in lifestyle, consisting of: Increasing regular physical activity focusing on endurance sports (avoiding high intensity sports (e.g. heavy weight lifting), Weight control for prevention/reduction of obesity, Healthy diet and correction of possible lipid disorders, No smoking (smoking increases the risk of dialysis 5-10-fold!), Low salt intake, Avoidance of using so-called non-steroid antiphlogistic drugs as pain killers, e.g. diclofenac, ibuprofen, indomethacine (aspirin, paracetamol and opiates are safe as far as the kidneys are concerned). […] Immunosuppressive therapy, e.g. steroid therapy (corticosteroids): steroids are usually administered over several months (four-six months); other immunosuppressive drugs are only used in most severe cases.

• #39 IgA Nephropathy Treatment & Management: Approach Considerations, Medical Care, Diet

  https://emedicine.medscape.com/article/239927-treatment

  Additional supportive care measures, to be used as appropriate, include the following: Address cardiovascular risk, Dietary sodium restriction, Smoking cessation, Weight control, Exercise. […] IgA nephropathy is a common cause of glomerulonephritis. Although it is a benign disease in most patients, chronic kidney disease and end-stage kidney disease (ESKD) occur in about 20-40% of patients within 20 years of presentation. Currently, multiple treatment options are available; no one therapy is appropriate for all patients. […] General recommendations include the following: In patients with isolated hematuria (ie, without proteinuria or hypertension) monitor with urinalysis, kidney function testing, and blood pressure measurement. Treat hypertension early and aggressively with renin-angiotensin blockade; a reasonable goal is a blood pressure of 130/80 mm Hg if proteinuria is 1g/day. If proteinuria is 1 g/day, then 125/75 mm Hg should be the goal. Steroids are most beneficial if more than 1 g of proteinuria is present in a 24-hour urine specimen. Goal UPCR is 0.5-0.75 g/day with renin-angiotensin blockade. If UPCR is 1.5 g/day despite maximum renin-angiotensin blockade for 4-6 months, steroids can be added, but not if the GFR is 25 mL/min/1.73m2. If UPCR is persistently 0.75-1.5 g/day, the short-term benefits of steroid use remains uncertain. The presence of crescents on biopsy in a sample with more than 10 glomeruli is an indication for treatment with cyclophosphamide.

• #40 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  The choice of the therapeutic approach varies according to the individual’s condition and in particular the estimated risk of progression to end-stage kidney disease (ESKD). […] Essential at any stage of the disease are changes in lifestyle, consisting of: Increasing regular physical activity focusing on endurance sports (avoiding high intensity sports (e.g. heavy weight lifting), Weight control for prevention/reduction of obesity, Healthy diet and correction of possible lipid disorders, No smoking (smoking increases the risk of dialysis 5-10-fold!), Low salt intake, Avoidance of using so-called non-steroid antiphlogistic drugs as pain killers, e.g. diclofenac, ibuprofen, indomethacine (aspirin, paracetamol and opiates are safe as far as the kidneys are concerned). […] Immunosuppressive therapy, e.g. steroid therapy (corticosteroids): steroids are usually administered over several months (four-six months); other immunosuppressive drugs are only used in most severe cases.

• #41 Mayo Clinic Health Library – IgA nephropathy (Berger disease) | Swiss Medical Network

  https://www.swissmedical.net/en/healtcare-library/con-20166955

  Medicines to treat IgA nephropathy include: High blood pressure drugs. Medicines called angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) can lower blood pressure and reduce how much protein the body loses. […] The main goal of treatment is to keep you from needing dialysis or a kidney transplant. But either of those treatments can be lifesaving if your kidneys stop working well enough on their own. […] To help keep your kidneys healthier: Take steps to lower your blood pressure. This can help slow kidney damage from IgA nephropathy. Start with some healthy lifestyle changes. Limit how much sodium and fat you eat. Lose any extra weight. Get regular exercise. And if you drink alcohol, do so in moderation. Also take your blood pressure medicines as prescribed. […] Coping with severe forms of IgA nephropathy can be a challenge. But you don’t have to do it alone. If you have questions or you need guidance, talk with a member of your health care team.

• #42 IgA Nephropathy (Berger’s Disease): ERKNet voor Patiënten

  https://www.erknet.org/patients/nl/your-kidney-disease/iga-nephropathy/disease-information

  The choice of the therapeutic approach varies according to the individual’s condition and in particular the estimated risk of progression to end-stage kidney disease (ESKD). […] Essential at any stage of the disease are changes in lifestyle, consisting of: Increasing regular physical activity focusing on endurance sports (avoiding high intensity sports (e.g. heavy weight lifting), Weight control for prevention/reduction of obesity, Healthy diet and correction of possible lipid disorders, No smoking (smoking increases the risk of dialysis 5-10-fold!), Low salt intake, Avoidance of using so-called non-steroid antiphlogistic drugs as pain killers, e.g. diclofenac, ibuprofen, indomethacine (aspirin, paracetamol and opiates are safe as far as the kidneys are concerned). […] All these measures greatly improve the prognosis and decrease the risk of progression to kidney failure in IgAN.

• #43 IgA Nephropathy Treatment: Medication, Surgery, & More

  https://www.health.com/iga-nephropathy-treatment-8702877

  Your healthcare provider may recommend one or more of the following medications: Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs): Control hypertension (high blood pressure) and slow down kidney damage by reducing the amount of protein that passes into the urine through damaged kidneys. […] If Berger’s disease worsens and causes kidney failure, there are a few additional treatment options that your provider can use to help reduce symptoms. These include: Dialysis: This procedure uses a filtering machine to manually remove toxins and extra fluid from the blood when the kidneys can no longer effectively perform that function. […] There are several lifestyle adjustments that your healthcare provider may suggest to help support your treatment plan. This typically includes recommendations such as the following: Eat a nutritious diet: Includes foods low in sodium, saturated fat, and cholesterol to reduce swelling and lower blood pressure.

• #44 IgA Nephropathy Treatment & Management: Approach Considerations, Medical Care, Diet

  https://emedicine.medscape.com/article/239927-treatment

  Tonsillectomy is a controversial treatment for IgA nephropathy. Tonsillectomy may limit the production of degalactosylated IgA1 by reducing mucosal-associated lymphoid tissue (MALT). […] Kidney transplantation is effective in patients with IgA nephropathy, but the disorder frequently recurs after transplantation (20-60%). The higher recurrence rates in transplantation from living related donors suggest genetic susceptibility to the disease.

• #45 What is IgA Nephropathy? – Immunoglobulin A [Berger’s Disease]

  https://igan.org/faq/

  Your doctor may want to put you on a low-salt diet to minimize stress of the kidneys and prevent excess fluid retention that would strain your heart. […] The possibility of recurrent IgAN should not discourage patients from having a transplant, but they should be aware that a transplant is not a cure for the disease, merely a replacement organ.

• #46 What is IgA Nephropathy? – Immunoglobulin A [Berger’s Disease]

  https://igan.org/faq/

  Your doctor may want to put you on a low-salt diet to minimize stress of the kidneys and prevent excess fluid retention that would strain your heart. […] The possibility of recurrent IgAN should not discourage patients from having a transplant, but they should be aware that a transplant is not a cure for the disease, merely a replacement organ.

• #47 IgA Nephropathy (Berger’s Disease) – Nursing CE Central

  https://nursingcecentral.com/lessons/iga-nephropathy-bergers-disease/

  The primary goals of treatment are to induce remission and prevent complications. First-line agents for managing proteinuria and lowering blood pressure involve angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs), aiming for a target blood pressure of 130/80 mm Hg. […] The complexity of IgAN requires clinicians, pharmacists, nurses, and allied health professionals to collaborate in educating and supporting both the client and their family to achieve optimal outcomes. […] For clients progressing to ESRD, renal transplantation is a viable option, although there is a risk of IgAN recurrence in the transplanted kidney.

• #48 IgA nephropathy | infoKID

  https://infokid.org.uk/conditions/iga-nephropathy/

  It is very important that your child goes back to the hospital or clinic for follow-up appointments, especially to check for proteinuria (protein in the urine). You may also need to test your child’s urine at home. […] Your healthcare team will speak with you and your family about any long-term effects your child might have with IgA nephropathy. IgA nephropathy can be a chronic condition, which means that it does not go away and may get worse over time.

• #49 IgA Nephropathy Treatment & Management: Approach Considerations, Medical Care, Diet

  https://emedicine.medscape.com/article/239927-treatment

  Additional supportive care measures, to be used as appropriate, include the following: Address cardiovascular risk, Dietary sodium restriction, Smoking cessation, Weight control, Exercise. […] IgA nephropathy is a common cause of glomerulonephritis. Although it is a benign disease in most patients, chronic kidney disease and end-stage kidney disease (ESKD) occur in about 20-40% of patients within 20 years of presentation. Currently, multiple treatment options are available; no one therapy is appropriate for all patients. […] General recommendations include the following: In patients with isolated hematuria (ie, without proteinuria or hypertension) monitor with urinalysis, kidney function testing, and blood pressure measurement. Treat hypertension early and aggressively with renin-angiotensin blockade; a reasonable goal is a blood pressure of 130/80 mm Hg if proteinuria is 1g/day. If proteinuria is 1 g/day, then 125/75 mm Hg should be the goal. Steroids are most beneficial if more than 1 g of proteinuria is present in a 24-hour urine specimen. Goal UPCR is 0.5-0.75 g/day with renin-angiotensin blockade. If UPCR is 1.5 g/day despite maximum renin-angiotensin blockade for 4-6 months, steroids can be added, but not if the GFR is 25 mL/min/1.73m2. If UPCR is persistently 0.75-1.5 g/day, the short-term benefits of steroid use remains uncertain. The presence of crescents on biopsy in a sample with more than 10 glomeruli is an indication for treatment with cyclophosphamide.

• #50 IgA Nephropathy Treatment & Management: Approach Considerations, Medical Care, Diet

  https://emedicine.medscape.com/article/239927-treatment

  Additional supportive care measures, to be used as appropriate, include the following: Address cardiovascular risk, Dietary sodium restriction, Smoking cessation, Weight control, Exercise. […] IgA nephropathy is a common cause of glomerulonephritis. Although it is a benign disease in most patients, chronic kidney disease and end-stage kidney disease (ESKD) occur in about 20-40% of patients within 20 years of presentation. Currently, multiple treatment options are available; no one therapy is appropriate for all patients. […] General recommendations include the following: In patients with isolated hematuria (ie, without proteinuria or hypertension) monitor with urinalysis, kidney function testing, and blood pressure measurement. Treat hypertension early and aggressively with renin-angiotensin blockade; a reasonable goal is a blood pressure of 130/80 mm Hg if proteinuria is 1g/day. If proteinuria is 1 g/day, then 125/75 mm Hg should be the goal. Steroids are most beneficial if more than 1 g of proteinuria is present in a 24-hour urine specimen. Goal UPCR is 0.5-0.75 g/day with renin-angiotensin blockade. If UPCR is 1.5 g/day despite maximum renin-angiotensin blockade for 4-6 months, steroids can be added, but not if the GFR is 25 mL/min/1.73m2. If UPCR is persistently 0.75-1.5 g/day, the short-term benefits of steroid use remains uncertain. The presence of crescents on biopsy in a sample with more than 10 glomeruli is an indication for treatment with cyclophosphamide.

• #51 Improving Berger’s Disease Life Expectancy | myIgANcenter

  https://kidneydisease.myhealthteam.com/resources/improving-life-expectancy-with-kidney-disease-what-matters-most

  Immunoglobulin A nephropathy (IgAN) is a condition in which an immune system protein called IgA damages your glomeruli (filtering units in your kidney) and causes kidney disease. People with IgAN often progress to kidney failure within 10 to 15 years after diagnosis. […] A 2018 study in the southeastern United States found that life expectancy in people with IgA nephropathy decreased by about 10 years. In a 2019 population-based study from Sweden, researchers found that people with IgA nephropathy died about six years earlier than people without the disease. […] If your immune system is causing kidney damage such as in IgAN, C3 glomerulopathy, or lupus nephritis your treatment plan may include immunosuppressive drugs. These drugs can help calm your immune system and prevent further kidney damage. […] Most people with kidney disease die from heart disease, not kidney failure. It isn’t possible to prevent many types of kidney disease, such as IgAN. However, you can take actions like these to prevent heart disease.

• #52 IgA nephropathy | infoKID

  https://infokid.org.uk/conditions/iga-nephropathy/

  It is very important that your child goes back to the hospital or clinic for follow-up appointments, especially to check for proteinuria (protein in the urine). You may also need to test your child’s urine at home. […] Your healthcare team will speak with you and your family about any long-term effects your child might have with IgA nephropathy. IgA nephropathy can be a chronic condition, which means that it does not go away and may get worse over time.

• #53 Tracking IgA nephropathy episodes important to improve patient comfort | UCI Health | Orange County, CA

  https://www.ucihealth.org/news/2024/12/iga-nephropathy-swelling

  When the protein immunoglobulin A builds up in the kidneys, it results in IgA nephropathy (IgAN), a progressive condition that can cause painful inflammation and swelling. […] Also known as Berger disease, its symptoms include high blood pressure, urine color changes and swelling around the eyes, especially in the morning. […] The mainstay of treatment involves medications that address both blood pressure and issues directly related to IgAN, but there are some helpful strategies that can reduce swelling in a short-term way to make you more comfortable. […] Chang adds that tracking swelling episodes can give your physician valuable information about the frequency of episodes and whether the IgAN is progressing.

• #54 IgA Nephropathy (Berger’s Disease): Causes, Symptoms, & Treatment

  https://www.webmd.com/a-to-z-guides/what-is-iga-nephropathy

  Your doctor may want to put you on a low-salt diet. This reduces the stress on your kidneys and heart. A nutritionist or dietitian can help you adjust your meals to adjust to your new eating plan. […] Currently, there is no cure for IgA nephropathy, but there have been a lot of new medications developed and approved for the treatment of IgA nephropathy that seem to control protein loss and help decrease the fall in kidney function over time. […] These meds can reduce the protein in your urine, control blood pressure, remove extra fluid from your blood, manage your immune system, and lower your cholesterol. […] Along with regular checkups with your doctor to monitor your kidneys and other symptoms, you can do some things at home to boost your kidney health. […] Dealing with a chronic illness, such as IgA nephropathy, can take a toll on your mental health. […] The goal of early detection and treatment is to keep your kidneys working well and avoid kidney failure.

• #55 IgA Nephropathy (Berger Disease): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/5990-iga-nephropathy

  Some research shows that a tonsillectomy (tonsil removal) can benefit a small portion of people who have IgA nephropathy. Talk to your healthcare provider to see if this may be an option for you. […] Its a good idea to schedule regular wellness checkups with a healthcare provider. Early detection can help prevent IgA nephropathy from developing into kidney failure. You should also work with a provider to help manage any other conditions that can affect your kidneys, including high blood pressure and diabetes. […] Go to the nearest emergency room if you have IgA nephropathy and develop symptoms of kidney failure, including: Feeling more tired than usual (fatigue); Peeing more or less than expected; Loss of appetite; Difficulty sleeping or focusing. […] With proper treatment, many people with IgA nephropathy can live long, fulfilling lives. They can continue working, going to school and participating in activities they love.

• #56 IgA nephropathy (IgAN) | American Kidney Fund

  https://www.kidneyfund.org/all-about-kidneys/other-kidney-diseases/iga-nephropathy

  If you are close to kidney failure, it’s important to have open conversations with your healthcare team about treatment options and what is best for you. Treatments available for kidney failure include dialysis (hemodialysis or peritoneal dialysis) and a kidney transplant. […] Living with IgA nephropathy can affect your mental and emotional health. Depression, anxiety and other mental health issues are common in people with kidney disease. […] If you notice changes to your mental health, these activities may help you feel better: Be active for at least 30 minutes most days of the week. […] If you want to talk to a professional, ask a member of your treatment team for a referral to a mental health therapist, counselor or social worker. […] A dietitian (an expert on food and nutrition) can help you make a kidney-friendly eating plan that works for you.

• #57 Furthering Managed Care Through Advances in IgA Nephropathy Therapy

  https://www.managedhealthcareexecutive.com/view/furthering-managed-care-through-advances-in-iga-nephropathy-therapy

  Managing IgAN requires comprehensive strategies to increase disease awareness, address its underdiagnosis and improve patient outcomes. If left undiagnosed and untreated, IgAN carries a significant mortality risk; further, it is closely linked to the development of ESRD. Early diagnosis and treatment intervention may delay disease progression, reduce overall healthcare use and extend the lifespan of patients. Care management programs that focus on the early detection and treatment of IgAN may reduce healthcare expenditures on renal replacement therapies and improve patient outcomes by slowing disease progression. […] Community-based screening programs that are integrated into population health interventions can help with early identification of high-risk patients and allow for timely medical interventions to delay CKD progression. Early risk stratification and intervention including timely access to antihypertensives and supportive care for patients with CKD has demonstrated cost savings and improved patient outcomes in renal disease. Managed care professionals can play a crucial role in medication management of kidney disease. Polypharmacy is common among CKD and dialysis patients, who may use up to 10 to 12 medications on average; these patients are at increased risk for medication-related side-effects and drug interactions. In addition to optimizing pharmacotherapy, managed care professionals can support patient education initiatives to promote lifestyle modifications.

• #58 IgA Nephropathy (Berger’s Disease): Diet, Symptoms, and More

  https://www.healthline.com/health/iga-nephropathy-bergers

  People with kidney failure will need dialysis, a process where the blood is filtered with a machine, or a kidney transplant. Even after a transplant, the condition can come back in the new kidney. […] If you get diagnosed with IgA, make some changes. Be your best advocate, learn about the disease, ask your doctor questions when you go on your visits and get your labs, and to try to find ways to manage that mental stress that comes with knowing you have this. […] The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) recommends limiting sodium intake to lower your blood pressure and help reduce swelling. […] Since the DASH diet is meant to help people lower their blood pressure, it may be helpful for people with IgA nephropathy who need to keep their blood pressure levels within a specific range. […] A doctor will work with you to develop a treatment plan if you’re diagnosed with IgA nephropathy.

• #59 IgA nephropathy (IgAN) | American Kidney Fund

  https://www.kidneyfund.org/all-about-kidneys/other-kidney-diseases/iga-nephropathy

  If you are close to kidney failure, it’s important to have open conversations with your healthcare team about treatment options and what is best for you. Treatments available for kidney failure include dialysis (hemodialysis or peritoneal dialysis) and a kidney transplant. […] Living with IgA nephropathy can affect your mental and emotional health. Depression, anxiety and other mental health issues are common in people with kidney disease. […] If you notice changes to your mental health, these activities may help you feel better: Be active for at least 30 minutes most days of the week. […] If you want to talk to a professional, ask a member of your treatment team for a referral to a mental health therapist, counselor or social worker. […] A dietitian (an expert on food and nutrition) can help you make a kidney-friendly eating plan that works for you.

• #60 IgA nephropathy (IgAN) | American Kidney Fund

  https://www.kidneyfund.org/all-about-kidneys/other-kidney-diseases/iga-nephropathy

  If you are close to kidney failure, it’s important to have open conversations with your healthcare team about treatment options and what is best for you. Treatments available for kidney failure include dialysis (hemodialysis or peritoneal dialysis) and a kidney transplant. […] Living with IgA nephropathy can affect your mental and emotional health. Depression, anxiety and other mental health issues are common in people with kidney disease. […] If you notice changes to your mental health, these activities may help you feel better: Be active for at least 30 minutes most days of the week. […] If you want to talk to a professional, ask a member of your treatment team for a referral to a mental health therapist, counselor or social worker. […] A dietitian (an expert on food and nutrition) can help you make a kidney-friendly eating plan that works for you.

• #61 IgA Nephropathy Treatment: Medication, Surgery, & More

  https://www.health.com/iga-nephropathy-treatment-8702877

  Although there isn’t a cure for IgA nephropathy yet, available treatment options can help prevent or delay damage to your kidneys, slowing the progression of the condition. […] Many people who have Berger’s disease can live a healthy life. Receiving a diagnosis for any condition can be scary, but medical experts recommend these tips to help you process your condition and learn to live well with it: Stay active through exercise and physical movement most days of the week, if possible.

• #62 IgA Nephropathy: Stages, Symptoms, Diagnosis, Treatment

  https://www.health.com/iga-nephropathy-stages-8702883

  In these early stages, your provider will want to focus on avoiding complications from IgA nephropathy, such as high blood pressure or diabetes, and may suggest the following: Maintaining healthy blood pressure and blood sugar levels, Taking medications (like statins) to help protect against heart disease and further kidney damage, Considering the pros and cons of medications that target the immune system directly (like corticosteroids) before too much kidney damage has occurred, Recommended lifestyle changes, like eating a kidney-friendly diet and avoiding smoking. […] Your healthcare provider should pursue an aggressive treatment strategy to prevent this from occurring. […] Follow your treatment plan closely and discuss it with your healthcare provider if you have any questions or concerns. Research shows that prescribed medications for IgA nephropathy help control blood pressure and reduce the amount of protein in urine, ultimately slowing or preventing damage to the kidneys. […] Managing your stress levels, particularly through mindfulness techniques like yoga and meditation, has been shown to help improve depression symptoms, heart and lung function, and overall quality of life in people with IgA nephropathy and chronic kidney disease.

• #63 IgA Nephropathy – RKD – About IgAN & Find Resources

  https://travere.com/our-science/therapeutic-areas/iga-nephropathy-igan/

  IgA nephropathy (IgAN), also called Berger’s disease, is a type of glomerulonephritis. Glomerulonephritis is inflammation of the glomeruli – the blood vessels in the kidneys that filter wastes and excess fluids from the blood and excrete them in the urine. […] Treatment aims to reduce proteinuria to less than 1 g/day and reduce blood pressure which is important for long-term preservation of kidney function. […] After his unexpected IgAN diagnosis, Jeff found strength in his community and care team—empowering him to take control of his health and raise awareness for others facing rare kidney disease. […] From avid hiker to kidney failure survivor, Stephanie’s journey with IgAN and FSGS has been one of resilience, community, and hope. […] After a decade with IgAN, Stuart’s kidney function declined—until a lifesaving donation from his wife changed everything.

• #64 IgA nephropathy (IgAN) | American Kidney Fund

  https://www.kidneyfund.org/all-about-kidneys/other-kidney-diseases/iga-nephropathy

  If you are close to kidney failure, it’s important to have open conversations with your healthcare team about treatment options and what is best for you. Treatments available for kidney failure include dialysis (hemodialysis or peritoneal dialysis) and a kidney transplant. […] Living with IgA nephropathy can affect your mental and emotional health. Depression, anxiety and other mental health issues are common in people with kidney disease. […] If you notice changes to your mental health, these activities may help you feel better: Be active for at least 30 minutes most days of the week. […] If you want to talk to a professional, ask a member of your treatment team for a referral to a mental health therapist, counselor or social worker. […] A dietitian (an expert on food and nutrition) can help you make a kidney-friendly eating plan that works for you.

• #65 IgA Nephropathy (Berger Disease): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/5990-iga-nephropathy

  Some research shows that a tonsillectomy (tonsil removal) can benefit a small portion of people who have IgA nephropathy. Talk to your healthcare provider to see if this may be an option for you. […] Its a good idea to schedule regular wellness checkups with a healthcare provider. Early detection can help prevent IgA nephropathy from developing into kidney failure. You should also work with a provider to help manage any other conditions that can affect your kidneys, including high blood pressure and diabetes. […] Go to the nearest emergency room if you have IgA nephropathy and develop symptoms of kidney failure, including: Feeling more tired than usual (fatigue); Peeing more or less than expected; Loss of appetite; Difficulty sleeping or focusing. […] With proper treatment, many people with IgA nephropathy can live long, fulfilling lives. They can continue working, going to school and participating in activities they love.

• #66 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  The lives of children/adults with IgA nephropathy should not be fundamentally different from the lives of children/adults without the condition. […] It is especially recommended to adopt a healthy lifestyle to minimise additional risk factors that may damage the kidneys. This includes physical activity, weight control (preventing obesity), healthy diet, limiting salt intake and avoiding drugs that have a potentially nephrotoxic effect. […] If you need support or have any questions about illness, the disease course, or long-term outcomes, please do not hesitate to talk to your GP, nephrologist or paediatric nephrologist.

• #67 CE Activity | IgA Nephropathy (Berger Disease) | NPs

  https://www.statpearls.com/nursepractitioner/ce/activity/95477

  At the conclusion of this activity, the learner will be better able to: […] Implement evidence-based management strategies for IgA nephropathy, including pharmacological interventions, lifestyle modifications, and dietary recommendations. […] Collaborate with interprofessional healthcare providers to optimize IgA nephropathy management by selecting appropriate immunosuppressive agents and supportive therapies tailored to an individual’s disease course and risk factors. […] Outline the pharmacologic therapy as it applies to IgA Nephropathy (Berger Disease).

• #68 IgA Nephropathy (Berger’s Disease) – Nursing CE Central

  https://nursingcecentral.com/lessons/iga-nephropathy-bergers-disease/

  The primary goals of treatment are to induce remission and prevent complications. First-line agents for managing proteinuria and lowering blood pressure involve angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs), aiming for a target blood pressure of 130/80 mm Hg. […] The complexity of IgAN requires clinicians, pharmacists, nurses, and allied health professionals to collaborate in educating and supporting both the client and their family to achieve optimal outcomes. […] For clients progressing to ESRD, renal transplantation is a viable option, although there is a risk of IgAN recurrence in the transplanted kidney.

• #69 IgA nephropathy (Berger disease) – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/iga-nephropathy/diagnosis-treatment/drc-20352274

  IgA nephropathy is often found after you notice blood in your urine. […] Our caring team of Mayo Clinic experts can help you with your iga nephropathy (berger disease)-related health concerns. […] There’s no cure for IgA nephropathy. […] For others, medicines can slow the disease from becoming worse and help manage symptoms. […] The main goal of treatment is to keep you from needing dialysis or a kidney transplant. […] To help keep your kidneys healthier: Take steps to lower your blood pressure. […] If you have questions or you need guidance, talk with a member of your health care team. […] You’re likely to start by seeing your primary doctor. But you might be referred to a doctor who is trained to treat kidney disorders, called a nephrologist. […] Ask your doctor if you should cut back on protein. This may help slow IgA nephropathy from becoming worse and protect your kidneys.

• #70 IgA Nephropathy (Berger Disease): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/5990-iga-nephropathy

  IgA nephropathy, or Bergers disease, is a kidney disease in which IgA antibodies build up abnormally. Over time, it leads to kidney damage or kidney failure. Symptoms include blood in your pee, swelling and flank pain. Medications can slow the diseases progress. But some people may need dialysis or a kidney transplant. […] Treatment can slow the progress of the disease and prevent ESRD. If you have IgA nephropathy, your healthcare provider will probably refer you to a nephrologist, a kidney disease specialist. […] Treatment for IgA nephropathy includes medication to: Regulate blood pressure with angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), or other medicines; Remove extra fluid with a diuretic; Control your immune system to lower kidney inflammation with prescribed steroids such as prednisone or cyclophosphamide, a different medicine; Lower your cholesterol levels with medications such as statins.

• #71 IgA Nephropathy (Berger’s Disease): Causes, Symptoms, & Treatment

  https://www.webmd.com/a-to-z-guides/what-is-iga-nephropathy

  Immunoglobulin A (IgA) nephropathy, also called Bergers disease, is an autoimmune disease that affects your kidneys. […] Early detection and treatment can limit the harm IgA nephropathy can do to your kidneys. […] If you have IgA nephropathy for a long time, it raises your risk of complications such as high blood pressure, kidney failure that comes on suddenly, losing kidney function slowly over time (chronic kidney failure), nephrotic syndrome, which is a group of symptoms including high protein in your urine, swelling, and high cholesterol, and heart or cardiovascular problems. […] Your regular doctor may be the first person you go to if you are having symptoms and they may also be the first to diagnose you. They can monitor your health as you treat your IgA nephropathy, but they may also refer you to specialists.

• #72 IgA Nephropathy Treatment: Medication, Surgery, & More

  https://www.health.com/iga-nephropathy-treatment-8702877

  Immunoglobulin A nephropathy (known as IgA nephropathy or Berger’s disease) is a rare kidney disease that occurs when the body’s immune system response causes IgA antibodies to build up in the kidneys. […] While there’s no cure at this time, treatment relieves symptoms, slows kidney damage, and prevents kidney failure. […] If you receive a diagnosis for this condition, your primary care provider, a nephrologist (a doctor who specializes in kidney health), and a hypertension specialist (a provider who specializes in managing high blood pressure) will oversee your treatment. […] IgA nephropathy is a kidney disease, so treatment for it focuses on managing symptoms and slowing down or preventing kidney damage. Medications are a primary treatment option for this condition, as they can help: Reduce inflammation, Control blood pressure, Remove extra fluid from the body, Lower cholesterol levels.

• #73 IgA Nephropathy (Berger’s Disease) – Nursing CE Central

  https://nursingcecentral.com/lessons/iga-nephropathy-bergers-disease/

  The primary goals of treatment are to induce remission and prevent complications. First-line agents for managing proteinuria and lowering blood pressure involve angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs), aiming for a target blood pressure of 130/80 mm Hg. […] The complexity of IgAN requires clinicians, pharmacists, nurses, and allied health professionals to collaborate in educating and supporting both the client and their family to achieve optimal outcomes. […] For clients progressing to ESRD, renal transplantation is a viable option, although there is a risk of IgAN recurrence in the transplanted kidney.

• #74 IgA nephropathy (IgAN) | American Kidney Fund

  https://www.kidneyfund.org/all-about-kidneys/other-kidney-diseases/iga-nephropathy

  If you are close to kidney failure, it’s important to have open conversations with your healthcare team about treatment options and what is best for you. Treatments available for kidney failure include dialysis (hemodialysis or peritoneal dialysis) and a kidney transplant. […] Living with IgA nephropathy can affect your mental and emotional health. Depression, anxiety and other mental health issues are common in people with kidney disease. […] If you notice changes to your mental health, these activities may help you feel better: Be active for at least 30 minutes most days of the week. […] If you want to talk to a professional, ask a member of your treatment team for a referral to a mental health therapist, counselor or social worker. […] A dietitian (an expert on food and nutrition) can help you make a kidney-friendly eating plan that works for you.

• #75 Furthering Managed Care Through Advances in IgA Nephropathy Therapy

  https://www.managedhealthcareexecutive.com/view/furthering-managed-care-through-advances-in-iga-nephropathy-therapy

  Managing IgAN requires comprehensive strategies to increase disease awareness, address its underdiagnosis and improve patient outcomes. If left undiagnosed and untreated, IgAN carries a significant mortality risk; further, it is closely linked to the development of ESRD. Early diagnosis and treatment intervention may delay disease progression, reduce overall healthcare use and extend the lifespan of patients. Care management programs that focus on the early detection and treatment of IgAN may reduce healthcare expenditures on renal replacement therapies and improve patient outcomes by slowing disease progression. […] Community-based screening programs that are integrated into population health interventions can help with early identification of high-risk patients and allow for timely medical interventions to delay CKD progression. Early risk stratification and intervention including timely access to antihypertensives and supportive care for patients with CKD has demonstrated cost savings and improved patient outcomes in renal disease. Managed care professionals can play a crucial role in medication management of kidney disease. Polypharmacy is common among CKD and dialysis patients, who may use up to 10 to 12 medications on average; these patients are at increased risk for medication-related side-effects and drug interactions. In addition to optimizing pharmacotherapy, managed care professionals can support patient education initiatives to promote lifestyle modifications.

• #76 IgA nephropathy (IgAN) | American Kidney Fund

  https://www.kidneyfund.org/all-about-kidneys/other-kidney-diseases/iga-nephropathy

  If you are close to kidney failure, it’s important to have open conversations with your healthcare team about treatment options and what is best for you. Treatments available for kidney failure include dialysis (hemodialysis or peritoneal dialysis) and a kidney transplant. […] Living with IgA nephropathy can affect your mental and emotional health. Depression, anxiety and other mental health issues are common in people with kidney disease. […] If you notice changes to your mental health, these activities may help you feel better: Be active for at least 30 minutes most days of the week. […] If you want to talk to a professional, ask a member of your treatment team for a referral to a mental health therapist, counselor or social worker. […] A dietitian (an expert on food and nutrition) can help you make a kidney-friendly eating plan that works for you.

• #77 IgA Nephropathy (Berger’s Disease) – Nursing CE Central

  https://nursingcecentral.com/lessons/iga-nephropathy-bergers-disease/

  The primary goals of treatment are to induce remission and prevent complications. First-line agents for managing proteinuria and lowering blood pressure involve angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs), aiming for a target blood pressure of 130/80 mm Hg. […] The complexity of IgAN requires clinicians, pharmacists, nurses, and allied health professionals to collaborate in educating and supporting both the client and their family to achieve optimal outcomes. […] For clients progressing to ESRD, renal transplantation is a viable option, although there is a risk of IgAN recurrence in the transplanted kidney.

• #78 New Primary Immunoglobulin A Nephropathy treatments 2025 | Everyone.org

  https://everyone.org/explore/treatment/?id=106

  Corticosteroids, such as prednisone, may also be prescribed for patients who do not respond adequately to ACE inhibitors or ARBs. […] Therefore, careful patient selection and monitoring are necessary when considering corticosteroid therapy. […] Patients should receive regular monitoring of kidney function, blood pressure, and proteinuria levels. […] Treatment of hypertension, hyperlipidemia, anemia, and metabolic acidosis should be optimized to reduce cardiovascular risks and slow kidney disease progression. […] In conclusion, treatment options for Primary IgA Nephropathy range from standard supportive therapies, including ACE inhibitors, ARBs, and corticosteroids, to newly approved targeted therapies such as Tarpeyo. […] Individualized treatment plans, careful monitoring, and lifestyle modifications remain essential components of effective disease management.

• #79 New Primary Immunoglobulin A Nephropathy treatments 2025 | Everyone.org

  https://everyone.org/explore/treatment/?id=106

  Primary Immunoglobulin A (IgA) Nephropathy, also known as Berger’s disease, is a kidney disorder characterized by the accumulation of IgA antibodies in the kidneys, leading to inflammation and impaired kidney function. […] Early detection and monitoring are important to reduce the risk of progression to chronic kidney disease or kidney failure. […] Treatment options for IgA Nephropathy vary depending on the severity of the condition and individual patient needs. […] Patients should discuss their individual condition and treatment goals carefully with their healthcare provider to determine the most appropriate medication regimen. […] The primary goal of IgAN treatment is to reduce proteinuria (protein in the urine), control blood pressure, and slow the progression of kidney damage. […] Standard treatment options include angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs), which help lower blood pressure and reduce proteinuria.

• #80 Furthering Managed Care Through Advances in IgA Nephropathy Therapy

  https://www.managedhealthcareexecutive.com/view/furthering-managed-care-through-advances-in-iga-nephropathy-therapy

  Managing IgAN requires comprehensive strategies to increase disease awareness, address its underdiagnosis and improve patient outcomes. If left undiagnosed and untreated, IgAN carries a significant mortality risk; further, it is closely linked to the development of ESRD. Early diagnosis and treatment intervention may delay disease progression, reduce overall healthcare use and extend the lifespan of patients. Care management programs that focus on the early detection and treatment of IgAN may reduce healthcare expenditures on renal replacement therapies and improve patient outcomes by slowing disease progression. […] Community-based screening programs that are integrated into population health interventions can help with early identification of high-risk patients and allow for timely medical interventions to delay CKD progression. Early risk stratification and intervention including timely access to antihypertensives and supportive care for patients with CKD has demonstrated cost savings and improved patient outcomes in renal disease. Managed care professionals can play a crucial role in medication management of kidney disease. Polypharmacy is common among CKD and dialysis patients, who may use up to 10 to 12 medications on average; these patients are at increased risk for medication-related side-effects and drug interactions. In addition to optimizing pharmacotherapy, managed care professionals can support patient education initiatives to promote lifestyle modifications.

• #81 IgA Nephropathy (Berger’s Disease) – Nursing CE Central

  https://nursingcecentral.com/lessons/iga-nephropathy-bergers-disease/

  The primary goals of treatment are to induce remission and prevent complications. First-line agents for managing proteinuria and lowering blood pressure involve angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs), aiming for a target blood pressure of 130/80 mm Hg. […] The complexity of IgAN requires clinicians, pharmacists, nurses, and allied health professionals to collaborate in educating and supporting both the client and their family to achieve optimal outcomes. […] For clients progressing to ESRD, renal transplantation is a viable option, although there is a risk of IgAN recurrence in the transplanted kidney.

• #82 CE Activity | IgA Nephropathy (Berger Disease) | NPs

  https://www.statpearls.com/nursepractitioner/ce/activity/95477

  At the conclusion of this activity, the learner will be better able to: […] Implement evidence-based management strategies for IgA nephropathy, including pharmacological interventions, lifestyle modifications, and dietary recommendations. […] Collaborate with interprofessional healthcare providers to optimize IgA nephropathy management by selecting appropriate immunosuppressive agents and supportive therapies tailored to an individual’s disease course and risk factors. […] Outline the pharmacologic therapy as it applies to IgA Nephropathy (Berger Disease).

• #83 CE Activity | IgA Nephropathy (Berger Disease) | Nurses

  https://www.statpearls.com/nurse/ce/activity/102258

  At the conclusion of this activity, the learner will be better able to: Identify the clinical features and laboratory findings suggestive of IgA nephropathy. Implement evidence-based management strategies for IgA nephropathy, including pharmacological interventions, lifestyle modifications, and dietary recommendations. Assess the severity and progression of IgA nephropathy through regular monitoring of renal function, proteinuria, and other relevant parameters. Collaborate with interprofessional healthcare providers to optimize IgA nephropathy management by selecting appropriate immunosuppressive agents and supportive therapies tailored to an individual’s disease course and risk factors.

• #84 IgA nephropathy | infoKID

  https://infokid.org.uk/conditions/iga-nephropathy/

  It is very important that your child goes back to the hospital or clinic for follow-up appointments, especially to check for proteinuria (protein in the urine). You may also need to test your child’s urine at home. […] Your healthcare team will speak with you and your family about any long-term effects your child might have with IgA nephropathy. IgA nephropathy can be a chronic condition, which means that it does not go away and may get worse over time.

• #85 New Primary Immunoglobulin A Nephropathy treatments 2025 | Everyone.org

  https://everyone.org/explore/treatment/?id=106

  Corticosteroids, such as prednisone, may also be prescribed for patients who do not respond adequately to ACE inhibitors or ARBs. […] Therefore, careful patient selection and monitoring are necessary when considering corticosteroid therapy. […] Patients should receive regular monitoring of kidney function, blood pressure, and proteinuria levels. […] Treatment of hypertension, hyperlipidemia, anemia, and metabolic acidosis should be optimized to reduce cardiovascular risks and slow kidney disease progression. […] In conclusion, treatment options for Primary IgA Nephropathy range from standard supportive therapies, including ACE inhibitors, ARBs, and corticosteroids, to newly approved targeted therapies such as Tarpeyo. […] Individualized treatment plans, careful monitoring, and lifestyle modifications remain essential components of effective disease management.

• #86 IgA Nephropathy (Berger’s Disease) – Nursing CE Central

  https://nursingcecentral.com/lessons/iga-nephropathy-bergers-disease/

  Immunoglobulin A nephropathy (IgAN), also known as Berger disease, is a major contributor to glomerulonephritis and kidney failure. Early recognition and management are essential to slow disease progression and preserve kidney function. […] The clinical course of the disease has a gradual progression with 20% and 50% of clients developing end-stage renal disease within 20 years of diagnosis. […] The admission team transfused three units of packed red blood cells and initiated dialysis. They corrected the Vitamin B12 deficiency and started intravenous antibiotics, antacids, nebulization, and oxygen therapy. The team provided supportive care throughout the hospital stay and continued dialysis as a life-saving measure. […] The management of IgA nephropathy (IgAN) starts by confirming the diagnosis through a renal biopsy, while also excluding potential secondary causes. Key considerations for formulating a management plan include assessing proteinuria, estimated glomerular filtration rate (eGFR), blood pressure, and histological findings.

• #87 Furthering Managed Care Through Advances in IgA Nephropathy Therapy

  https://www.managedhealthcareexecutive.com/view/furthering-managed-care-through-advances-in-iga-nephropathy-therapy

  Managing IgAN requires comprehensive strategies to increase disease awareness, address its underdiagnosis and improve patient outcomes. If left undiagnosed and untreated, IgAN carries a significant mortality risk; further, it is closely linked to the development of ESRD. Early diagnosis and treatment intervention may delay disease progression, reduce overall healthcare use and extend the lifespan of patients. Care management programs that focus on the early detection and treatment of IgAN may reduce healthcare expenditures on renal replacement therapies and improve patient outcomes by slowing disease progression. […] Community-based screening programs that are integrated into population health interventions can help with early identification of high-risk patients and allow for timely medical interventions to delay CKD progression. Early risk stratification and intervention including timely access to antihypertensives and supportive care for patients with CKD has demonstrated cost savings and improved patient outcomes in renal disease. Managed care professionals can play a crucial role in medication management of kidney disease. Polypharmacy is common among CKD and dialysis patients, who may use up to 10 to 12 medications on average; these patients are at increased risk for medication-related side-effects and drug interactions. In addition to optimizing pharmacotherapy, managed care professionals can support patient education initiatives to promote lifestyle modifications.

• #88 IgA nephropathy | infoKID

  https://infokid.org.uk/conditions/iga-nephropathy/

  It is very important that your child goes back to the hospital or clinic for follow-up appointments, especially to check for proteinuria (protein in the urine). You may also need to test your child’s urine at home. […] Your healthcare team will speak with you and your family about any long-term effects your child might have with IgA nephropathy. IgA nephropathy can be a chronic condition, which means that it does not go away and may get worse over time.

• #89 IgA nephropathy (IgAN) | American Kidney Fund

  https://www.kidneyfund.org/all-about-kidneys/other-kidney-diseases/iga-nephropathy

  If you are close to kidney failure, it’s important to have open conversations with your healthcare team about treatment options and what is best for you. Treatments available for kidney failure include dialysis (hemodialysis or peritoneal dialysis) and a kidney transplant. […] Living with IgA nephropathy can affect your mental and emotional health. Depression, anxiety and other mental health issues are common in people with kidney disease. […] If you notice changes to your mental health, these activities may help you feel better: Be active for at least 30 minutes most days of the week. […] If you want to talk to a professional, ask a member of your treatment team for a referral to a mental health therapist, counselor or social worker. […] A dietitian (an expert on food and nutrition) can help you make a kidney-friendly eating plan that works for you.

• #90 Mayo Clinic Health Library – IgA nephropathy (Berger disease) | Swiss Medical Network

  https://www.swissmedical.net/en/healtcare-library/con-20166955

  Medicines to treat IgA nephropathy include: High blood pressure drugs. Medicines called angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) can lower blood pressure and reduce how much protein the body loses. […] The main goal of treatment is to keep you from needing dialysis or a kidney transplant. But either of those treatments can be lifesaving if your kidneys stop working well enough on their own. […] To help keep your kidneys healthier: Take steps to lower your blood pressure. This can help slow kidney damage from IgA nephropathy. Start with some healthy lifestyle changes. Limit how much sodium and fat you eat. Lose any extra weight. Get regular exercise. And if you drink alcohol, do so in moderation. Also take your blood pressure medicines as prescribed. […] Coping with severe forms of IgA nephropathy can be a challenge. But you don’t have to do it alone. If you have questions or you need guidance, talk with a member of your health care team.

• #91 IgA nephropathy (Berger disease) | Beacon Health System

  https://www.beaconhealthsystem.org/library/diseases-and-conditions/iga-nephropathy-berger-disease?content_id=CON-20166955

  The main goal of treatment is to keep you from needing dialysis or a kidney transplant. But either of those treatments can be lifesaving if your kidneys stop working well enough on their own. […] To help keep your kidneys healthier: Take steps to lower your blood pressure. This can help slow kidney damage from IgA nephropathy. Start with some healthy lifestyle changes. Limit how much sodium and fat you eat. Lose any extra weight. Get regular exercise. And if you drink alcohol, do so in moderation. Also take your blood pressure medicines as prescribed. Keep track of your blood pressure at home. If your health care team asks you to do this, write down each blood pressure reading. Then bring the record with you to checkups. Eat less protein. Ask your doctor if you should cut back on protein. This may help slow IgA nephropathy from becoming worse and protect your kidneys.

• #92 IgA Nephropathy (Berger’s Disease) Treatment Options

  https://www.healthline.com/health/treatment-options-for-iga-nephropathy

  Doctors may prescribe a diuretic together with these medications to make them more effective. […] Another non-immunosuppressive medication is sparsentan, an endothelin and angiotensin II receptor antagonist. It lowers levels of protein in the urine in people with IgA nephropathy whose condition may progress quickly. […] Immunosuppressive medications for IgA nephropathy include: cyclophosphamide and corticosteroids, such as prednisone. […] Budesonide is another corticosteroid a doctor may prescribe for IgA nephropathy. It helps decrease inflammation in the kidneys and reduce levels of protein in the urine in people whose condition may progress quickly. […] A healthcare professional may recommend a variety of lifestyle changes to help you manage IgA nephropathy. […] These dietary modifications may include: Limiting the amount of sodium in your diet, following a diet that is low in saturated fats and cholesterol, and shifting toward a plant-based diet.

• #93 IgA Nephropathy (Berger’s Disease) Treatment Options

  https://www.healthline.com/health/treatment-options-for-iga-nephropathy

  A healthcare professional may also advise you to eat protein in moderation. […] Maintaining a healthy lifestyle can help you manage IgA nephropathy. […] Healthy lifestyle practices include: exercising regularly, limiting alcohol consumption, making efforts to maintain a moderate weight, getting enough sleep, avoiding smoking, and managing stress levels. […] IgA nephropathy can cause a variety of complications, including high blood pressure, kidney failure, and heart problems. […] High blood pressure and heart or cardiovascular problems may be treated with medication. […] Kidney failure may require dialysis or a kidney transplant. […] Treatment options include non-immunosuppressive and immunosuppressive medications and cholesterol-lowering medications. Your doctor might also recommend lifestyle and dietary changes to manage IgA nephropathy. […] Further treatments, such as dialysis and kidney transplant, may be required for complications from IgA nephropathy.

• #94 IgA nephropathy (IgAN) | American Kidney Fund

  https://www.kidneyfund.org/all-about-kidneys/other-kidney-diseases/iga-nephropathy

  If you are close to kidney failure, it’s important to have open conversations with your healthcare team about treatment options and what is best for you. Treatments available for kidney failure include dialysis (hemodialysis or peritoneal dialysis) and a kidney transplant. […] Living with IgA nephropathy can affect your mental and emotional health. Depression, anxiety and other mental health issues are common in people with kidney disease. […] If you notice changes to your mental health, these activities may help you feel better: Be active for at least 30 minutes most days of the week. […] If you want to talk to a professional, ask a member of your treatment team for a referral to a mental health therapist, counselor or social worker. […] A dietitian (an expert on food and nutrition) can help you make a kidney-friendly eating plan that works for you.

• #95 IgA Nephropathy (Berger’s Disease) Treatment Options

  https://www.healthline.com/health/treatment-options-for-iga-nephropathy

  A healthcare professional may also advise you to eat protein in moderation. […] Maintaining a healthy lifestyle can help you manage IgA nephropathy. […] Healthy lifestyle practices include: exercising regularly, limiting alcohol consumption, making efforts to maintain a moderate weight, getting enough sleep, avoiding smoking, and managing stress levels. […] IgA nephropathy can cause a variety of complications, including high blood pressure, kidney failure, and heart problems. […] High blood pressure and heart or cardiovascular problems may be treated with medication. […] Kidney failure may require dialysis or a kidney transplant. […] Treatment options include non-immunosuppressive and immunosuppressive medications and cholesterol-lowering medications. Your doctor might also recommend lifestyle and dietary changes to manage IgA nephropathy. […] Further treatments, such as dialysis and kidney transplant, may be required for complications from IgA nephropathy.

• #96 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  The choice of the therapeutic approach varies according to the individual’s condition and in particular the estimated risk of progression to end-stage kidney disease (ESKD). […] Essential at any stage of the disease are changes in lifestyle, consisting of: Increasing regular physical activity focusing on endurance sports (avoiding high intensity sports (e.g. heavy weight lifting), Weight control for prevention/reduction of obesity, Healthy diet and correction of possible lipid disorders, No smoking (smoking increases the risk of dialysis 5-10-fold!), Low salt intake, Avoidance of using so-called non-steroid antiphlogistic drugs as pain killers, e.g. diclofenac, ibuprofen, indomethacine (aspirin, paracetamol and opiates are safe as far as the kidneys are concerned). […] Immunosuppressive therapy, e.g. steroid therapy (corticosteroids): steroids are usually administered over several months (four-six months); other immunosuppressive drugs are only used in most severe cases.

• #97 IgA Nephropathy (Berger’s Disease) Treatment Options

  https://www.healthline.com/health/treatment-options-for-iga-nephropathy

  A healthcare professional may also advise you to eat protein in moderation. […] Maintaining a healthy lifestyle can help you manage IgA nephropathy. […] Healthy lifestyle practices include: exercising regularly, limiting alcohol consumption, making efforts to maintain a moderate weight, getting enough sleep, avoiding smoking, and managing stress levels. […] IgA nephropathy can cause a variety of complications, including high blood pressure, kidney failure, and heart problems. […] High blood pressure and heart or cardiovascular problems may be treated with medication. […] Kidney failure may require dialysis or a kidney transplant. […] Treatment options include non-immunosuppressive and immunosuppressive medications and cholesterol-lowering medications. Your doctor might also recommend lifestyle and dietary changes to manage IgA nephropathy. […] Further treatments, such as dialysis and kidney transplant, may be required for complications from IgA nephropathy.

• #98 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  The lives of children/adults with IgA nephropathy should not be fundamentally different from the lives of children/adults without the condition. […] It is especially recommended to adopt a healthy lifestyle to minimise additional risk factors that may damage the kidneys. This includes physical activity, weight control (preventing obesity), healthy diet, limiting salt intake and avoiding drugs that have a potentially nephrotoxic effect. […] If you need support or have any questions about illness, the disease course, or long-term outcomes, please do not hesitate to talk to your GP, nephrologist or paediatric nephrologist.

• #99 Mayo Clinic Health Library – IgA nephropathy (Berger disease) | Swiss Medical Network

  https://www.swissmedical.net/en/healtcare-library/con-20166955

  Medicines to treat IgA nephropathy include: High blood pressure drugs. Medicines called angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) can lower blood pressure and reduce how much protein the body loses. […] The main goal of treatment is to keep you from needing dialysis or a kidney transplant. But either of those treatments can be lifesaving if your kidneys stop working well enough on their own. […] To help keep your kidneys healthier: Take steps to lower your blood pressure. This can help slow kidney damage from IgA nephropathy. Start with some healthy lifestyle changes. Limit how much sodium and fat you eat. Lose any extra weight. Get regular exercise. And if you drink alcohol, do so in moderation. Also take your blood pressure medicines as prescribed. […] Coping with severe forms of IgA nephropathy can be a challenge. But you don’t have to do it alone. If you have questions or you need guidance, talk with a member of your health care team.

• #100 IgA Nephropathy (Berger’s Disease): ERKNet for Patients

  https://www.erknet.org/patients/your-kidney-disease/iga-nephropathy/disease-information

  The lives of children/adults with IgA nephropathy should not be fundamentally different from the lives of children/adults without the condition. […] It is especially recommended to adopt a healthy lifestyle to minimise additional risk factors that may damage the kidneys. This includes physical activity, weight control (preventing obesity), healthy diet, limiting salt intake and avoiding drugs that have a potentially nephrotoxic effect. […] If you need support or have any questions about illness, the disease course, or long-term outcomes, please do not hesitate to talk to your GP, nephrologist or paediatric nephrologist.

• #101 Mayo Clinic Health Library – IgA nephropathy (Berger disease) | Swiss Medical Network

  https://www.swissmedical.net/en/healtcare-library/con-20166955

  Medicines to treat IgA nephropathy include: High blood pressure drugs. Medicines called angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) can lower blood pressure and reduce how much protein the body loses. […] The main goal of treatment is to keep you from needing dialysis or a kidney transplant. But either of those treatments can be lifesaving if your kidneys stop working well enough on their own. […] To help keep your kidneys healthier: Take steps to lower your blood pressure. This can help slow kidney damage from IgA nephropathy. Start with some healthy lifestyle changes. Limit how much sodium and fat you eat. Lose any extra weight. Get regular exercise. And if you drink alcohol, do so in moderation. Also take your blood pressure medicines as prescribed. […] Coping with severe forms of IgA nephropathy can be a challenge. But you don’t have to do it alone. If you have questions or you need guidance, talk with a member of your health care team.

• #102 Furthering Managed Care Through Advances in IgA Nephropathy Therapy

  https://www.managedhealthcareexecutive.com/view/furthering-managed-care-through-advances-in-iga-nephropathy-therapy

  Immunoglobulin A nephropathy (IgAN), also known as Berger disease, is an autoimmune condition and the most common type of primary glomerulonephritis worldwide. IgAN is characterized by the accumulation of IgA complexes in the kidneys glomeruli, which results in progressive damage that can lead to chronic kidney disease (CKD). The ongoing glomerular damage disrupts the filtration barrier; over time, scarring of the nephrons occurs, culminating in end-stage renal disease (ESRD). Alarmingly, 40% to 53% of patients progress to ESRD within two decades of diagnosis. This severe progression necessitates interventions such as dialysis or kidney transplantation; either of these interventions significantly impacts the patients quality of life (QOL) and imposes substantial economic burdens. […] The primary aim of IgAN treatment is to prevent or delay progression to ESRD and preserve kidney function. In its 2021 clinical practice guideline for the management of glomerular diseases, Kidney Disease: Improving Global Outcomes (KDIGO) issued guidance for the management of IgAN absent any FDA-approved treatments. Recent advancements in understanding the pathogenesis of IgAN as an immune-mediated disease and the acceptance of surrogate outcomes for accelerated drug approval have led to a rapid increase in clinical trials exploring new therapeutic strategies that target specific disease pathways.

• #103 IgA Nephropathy (Berger’s Disease) Treatment Options

  https://www.healthline.com/health/treatment-options-for-iga-nephropathy

  Doctors may prescribe a diuretic together with these medications to make them more effective. […] Another non-immunosuppressive medication is sparsentan, an endothelin and angiotensin II receptor antagonist. It lowers levels of protein in the urine in people with IgA nephropathy whose condition may progress quickly. […] Immunosuppressive medications for IgA nephropathy include: cyclophosphamide and corticosteroids, such as prednisone. […] Budesonide is another corticosteroid a doctor may prescribe for IgA nephropathy. It helps decrease inflammation in the kidneys and reduce levels of protein in the urine in people whose condition may progress quickly. […] A healthcare professional may recommend a variety of lifestyle changes to help you manage IgA nephropathy. […] These dietary modifications may include: Limiting the amount of sodium in your diet, following a diet that is low in saturated fats and cholesterol, and shifting toward a plant-based diet.

• #104 IgA Nephropathy (Berger’s Disease) Treatment Options

  https://www.healthline.com/health/treatment-options-for-iga-nephropathy

  Doctors may prescribe a diuretic together with these medications to make them more effective. […] Another non-immunosuppressive medication is sparsentan, an endothelin and angiotensin II receptor antagonist. It lowers levels of protein in the urine in people with IgA nephropathy whose condition may progress quickly. […] Immunosuppressive medications for IgA nephropathy include: cyclophosphamide and corticosteroids, such as prednisone. […] Budesonide is another corticosteroid a doctor may prescribe for IgA nephropathy. It helps decrease inflammation in the kidneys and reduce levels of protein in the urine in people whose condition may progress quickly. […] A healthcare professional may recommend a variety of lifestyle changes to help you manage IgA nephropathy. […] These dietary modifications may include: Limiting the amount of sodium in your diet, following a diet that is low in saturated fats and cholesterol, and shifting toward a plant-based diet.

• #105 New Primary Immunoglobulin A Nephropathy treatments 2025 | Everyone.org

  https://everyone.org/explore/treatment/?id=106

  Corticosteroids, such as prednisone, may also be prescribed for patients who do not respond adequately to ACE inhibitors or ARBs. […] Therefore, careful patient selection and monitoring are necessary when considering corticosteroid therapy. […] Patients should receive regular monitoring of kidney function, blood pressure, and proteinuria levels. […] Treatment of hypertension, hyperlipidemia, anemia, and metabolic acidosis should be optimized to reduce cardiovascular risks and slow kidney disease progression. […] In conclusion, treatment options for Primary IgA Nephropathy range from standard supportive therapies, including ACE inhibitors, ARBs, and corticosteroids, to newly approved targeted therapies such as Tarpeyo. […] Individualized treatment plans, careful monitoring, and lifestyle modifications remain essential components of effective disease management.

• #106 Dapagliflozin Shown to Be Safe, Effective in Patients With CKD

  https://www.ajmc.com/view/dapagliflozin-shown-to-be-safe-effective-in-patients-with-ckd

  Dapagliflozin substantially slowed the progression of chronic kidney disease (CKD) in patients with immunoglobulin A nephropathy, according to a new study. […] Treatment with dapagliflozin substantially reduced the risk of chronic kidney disease progression in patients with immunoglobulin A (IgA) nephropathy when added to renin-angiotensin-system blockade, according to a new study published in Kidney International. […] The predominant strategy is to use supportive measures, including renin-angiotensin-aldosterone blockade. […] Immunosuppressive therapy is controversial and usually reserved for patients who don’t respond to supportive measures. […] This prespecified analysis of the DAPA-CKD study demonstrates that in patients with IgA nephropathy, when added to ACEi/ARB therapy, the authors concluded, dapagliflozin significantly and substantially reduces the risk of CKD progression with a favorable safety profile.

• #107 IgA nephropathy | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/iga-nephropathy?lang=us

  IgA nephropathy, also known as IgA nephritis or Berger disease, is a form of glomerulonephritis. […] Management depends on disease severity, with strategies including management of hypertension, proteinuria (e.g. ACE inhibitors, sparsentan, atrasentan), and immunosuppression.

• #108 Primary IGA Nephropathy Clinical Trial In Texas

  https://revivalresearch.org/studies/primary-iga-nephropathy-clinical-trials/

  The IgA Nephropathy Clinical Trial is a phase 3, double-blind, placebo-controlled research study. This means that neither you nor the study doctor will know which medication you receive. You may receive the placebo drug (medication without the active ingredient of the study medication) or the study drug. You will not be able to choose the drug you receive. The medication will be assigned to you by chance, like the flip of a coin. […] Your participation in the study will last for approximately 105 weeks. The study team will continue to monitor your health throughout your participation in the study. There is no cost to you to participate in the study and you will receive study-related care from expert physicians and health care professionals. […] You will receive full study-related care from healthcare experts including doctors and nurses. All tests conducted during the study and study-related care provided to you will be free of cost to you and your private health insurance.

• #109 Primary IGA Nephropathy Clinical Trial In Texas

  https://revivalresearch.org/studies/primary-iga-nephropathy-clinical-trials/

  The IgA Nephropathy Clinical Trial is a phase 3, double-blind, placebo-controlled research study. This means that neither you nor the study doctor will know which medication you receive. You may receive the placebo drug (medication without the active ingredient of the study medication) or the study drug. You will not be able to choose the drug you receive. The medication will be assigned to you by chance, like the flip of a coin. […] Your participation in the study will last for approximately 105 weeks. The study team will continue to monitor your health throughout your participation in the study. There is no cost to you to participate in the study and you will receive study-related care from expert physicians and health care professionals. […] You will receive full study-related care from healthcare experts including doctors and nurses. All tests conducted during the study and study-related care provided to you will be free of cost to you and your private health insurance.

• #110 Primary IGA Nephropathy Clinical Trial In Texas

  https://revivalresearch.org/studies/primary-iga-nephropathy-clinical-trials/

  The IgA Nephropathy Clinical Trial is a phase 3, double-blind, placebo-controlled research study. This means that neither you nor the study doctor will know which medication you receive. You may receive the placebo drug (medication without the active ingredient of the study medication) or the study drug. You will not be able to choose the drug you receive. The medication will be assigned to you by chance, like the flip of a coin. […] Your participation in the study will last for approximately 105 weeks. The study team will continue to monitor your health throughout your participation in the study. There is no cost to you to participate in the study and you will receive study-related care from expert physicians and health care professionals. […] You will receive full study-related care from healthcare experts including doctors and nurses. All tests conducted during the study and study-related care provided to you will be free of cost to you and your private health insurance.

• #111 Primary IGA Nephropathy Clinical Trial In Texas

  https://revivalresearch.org/studies/primary-iga-nephropathy-clinical-trials/

  IgA Nephropathy (also called Bergers Disease) is a kidney disease characterized by the accumulation of antibodies, specifically immunoglobulin A (IgA), in kidney tissue, further giving rise to inflammation. This inflammation poses a challenge of persistent kidney discomfort, and if left untreated, can lead to serious complications in the future. […] Right now, Revival Research Institute is investigating a novel drug that may help in advancing clinical research in nephrology and offer potential treatment for IgA Nephropathy. Additionally, our research aims to assess the safety and efficacy of investigational drugs. […] The study drug and study-related care is free for volunteers eligible for the study. If you qualify, you will receive a call from someone on our research staff. You may be asked to share your personal information regarding your complete medical history, overall health, and any medications you take.

• #112 IgA Nephropathy Treatment: Medication, Surgery, & More

  https://www.health.com/iga-nephropathy-treatment-8702877

  Although there isn’t a cure for IgA nephropathy yet, available treatment options can help prevent or delay damage to your kidneys, slowing the progression of the condition. […] Many people who have Berger’s disease can live a healthy life. Receiving a diagnosis for any condition can be scary, but medical experts recommend these tips to help you process your condition and learn to live well with it: Stay active through exercise and physical movement most days of the week, if possible.

• #113 New study sheds light on incidence of IgA nephropathy – Kaiser Permanente Department of Research & Evaluation

  https://www.kp-scalresearch.org/new-study-sheds-light-on-incidence-of-iga-nephropathy/

  IgA nephropathy, also known as Bergers disease, is a chronic kidney disease that occurs when the immune system produces abnormally formed antibodies that build up in the kidneys. […] In addition to providing a more solid estimate for the overall incidence of IgA nephropathy and describing the racial/ethnic groups most at risk, our study emphasized the importance of early diagnosis, Dr. Sim said. IgA nephropathy is a progressive disease and first manifests with isolated blood in the urine or mild proteinuria. We observed that our IgA nephropathy population was diagnosed at advanced disease as evidenced by their kidney function and the amount of proteinuria at biopsy. Earlier diagnosis and treatment can alter the course of the disease and delay or prevent kidney failure.

Zobacz więcej