Materiały źródłowe

• #1 The Burden of Overactive Bladder on US Public Health

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4821440/

  Overactive bladder (OAB) is a highly prevalent symptom condition that affects millions of US men and women. Not only can the symptoms of OAB be very bothersome, but OAB can have significant detrimental effects on many aspects of individuals lives, representing a particularly impactful health burden to quality of life and productivity. Estimates of the individual and societal costs for the management of OAB continue to rise, particularly as effective treatments remain elusive. As such, OAB represents a significant public health burden to the USA. […] Overactive bladder (OAB) is a symptom syndrome defined by urinary urgency (i.e., the sudden compelling desire to pass urine that is difficult to defer), with or without urge urinary incontinence (UI), usually with frequency and nocturia. As OAB is highly prevalent in the US population and accounts for considerable societal costs, it represents a significant public health burden to the USA.

• #2 Overactive Bladder Market Size, Growth, Trends – Industry Analysis & Forecast – GlobalData

  https://www.globaldata.com/store/report/overactive-bladder-epidemiology-analysis/

  Overactive bladder (OAB) syndrome is a group of urinary symptoms, defined as urinary urgency, usually with urinary frequency and nocturia, with or without urgency urinary incontinence (Abrams et al., 2003; Haylen et al., 2010). […] The clinical diagnosis is characterized by urinary urgency, with or without urge incontinence, usually with daytime and nighttime frequency, in the absence of a urinary tract infection or other obvious pathology (Lightner et al., 2019). […] This report provides an overview of the risk factors, comorbidities, and the global and historical epidemiological trends for OAB in the eight major markets (8MM: US, France, Germany, Italy, Spain, UK, Japan, and China). […] The report includes a 10-year epidemiology forecast for the total prevalent cases and diagnosed prevalent cases of OAB.

• #3 Review of the epidemiology of overactive bladder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4902138/

  Overactive bladder (OAB) is common in both men and women. It is a symptom complex that causes significant detriment to quality of life in patients. Although the prevalence of OAB is similar in both sexes, there are sex-specific differences in individual symptoms and the impact on quality of life. This review examines the major studies that looked at the epidemiology of OAB as it relates to both sexes. It focuses on both the overall prevalence rates and the incidence of individual symptoms. This paper also addresses the level of bother and quality of life in men and women with OAB. […] Overactive bladder (OAB) is a prevalent condition in both men and women. It may have a significant impact on overall quality of life, sexual function, sleep, and mental health. […] Numerous publications have studied the prevalence of OAB in developed countries and assessed the impact it has on quality of life with various results.

• #4 Review of the epidemiology of overactive bladder | RRU

  https://www.dovepress.com/review-of-the-epidemiology-of-overactive-bladder-peer-reviewed-fulltext-article-RRU

  Overactive bladder (OAB) is common in both men and women. It is a symptom complex that causes significant detriment to quality of life in patients. Although the prevalence of OAB is similar in both sexes, there are sex-specific differences in individual symptoms and the impact on quality of life. This review examines the major studies that looked at the epidemiology of OAB as it relates to both sexes. It focuses on both the overall prevalence rates and the incidence of individual symptoms. This paper also addresses the level of bother and quality of life in men and women with OAB. […] Overactive bladder (OAB) is a prevalent condition in both men and women. It may have a significant impact on overall quality of life, sexual function, sleep, and mental health. According to the International Continence Society (ICS) definition, OAB consists of urinary urgency with or without urge incontinence, often accompanied by frequency and nocturia. Numerous publications have studied the prevalence of OAB in developed countries and assessed the impact it has on quality of life with various results. Although the overall prevalence of OAB is similar between the two sexes, there are sex-specific differences in the prevalence of various symptoms within the OAB complex.

• #5

  https://link.springer.com/article/10.1007/s00192-024-06029-2

  This study aims to systematically estimate the global prevalence of overactive bladder (OAB), identify demographic and regional factors contributing to prevalence variations, and assess trends in prevalence over the past two decades. […] A total of 53 studies, encompassing 610,438 participants, were ultimately included in the analysis. The meta-analysis determined the global prevalence of OAB to be 20% (95% CI 0.180.21). Over the past 20 years, there has been an increase in OAB prevalence, rising from 18.1% (95% CI 0.130.23) to 23.9% (95% CI 0.190.29). […] The study highlights higher risks of OAB among obese individuals, women, and the elderly. OAB prevalence has shown an increasing trend over the past 20 years. […] Despite the extensive impact of OAB, its prevalence varies widely among countries and regions. Large-scale epidemiologic studies report prevalence rates ranging from 8.8% in China to 23.2% in the United States.

• #6

  https://journals.lww.com/co-obgyn/fulltext/2005/10000/overactive_bladder__epidemiology_and_social_impact.11.aspx?generateEpub=Article%7Cco-obgyn:2005:10000:00011%7C10.1097/01.gco.0000183529.26352.52%7C

  Overactive bladder epidemiology is a rapidly evolving field. The new terminology of lower urinary tract function, introduced in 2002, modified the definitions of all four components of overactive bladder. In the same year, the lack of specific information on overactive bladder prevalence was identified and consequently new studies were launched and recently published. […] Studies conducted in selected countries and populations suggested comparable prevalence data worldwide, although the syndrome is considered to be underreported. […] Recent epidemiological data confirm the increase in overactive bladder prevalence with age and suggest that most diet and lifestyle factors are not associated with the condition, with the exception of body mass index. […] The socioeconomic consequences of the overactive bladder syndrome were recently estimated in a large US study and a total cost of US$12.6 billion was calculated. […] Specific data on overactive bladder epidemiology are now available, providing new evidence about its relevance as a clinical issue.

• #7 Review of the epidemiology of overactive bladder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4902138/

  Although the overall prevalence of OAB is similar between the two sexes, there are sex-specific differences in the prevalence of various symptoms within the OAB complex. […] The EPIC study was a cross-sectional telephone survey of adults aged 18 years. […] The study had 19,000 participants and showed an overall OAB prevalence of 11.8%, with similar rates in men and women. […] The NOBLE program was developed to estimate the prevalence of OAB and its burden in the United States. […] The study showed an overall OAB prevalence of ~16% with no significant differences between the two sexes (16% in men, 16.9% in women). […] The epidemiology of lower urinary tract symptoms (EpiLUTS) survey was a population-based, cross-sectional survey conducted in the US, UK, and Sweden to evaluate the prevalence and bother of OAB.

• #8 Review of the epidemiology of overactive bladder | RRU

  https://www.dovepress.com/review-of-the-epidemiology-of-overactive-bladder-peer-reviewed-fulltext-article-RRU

  This is one of the largest population-based surveys that studied the prevalence of lower urinary tract symptoms (LUTS) and OAB. The EPIC study showed an overall OAB prevalence of 11.8%, with similar rates in men and women. The EPIC study showed that the prevalence of LUTS suggestive of OAB was 10.8% in men and 12.8% in women. It can be seen from the EPIC study that the incidence of LUTS in general was similar but slightly more common in women than in men. […] The NOBLE program was developed to estimate the prevalence of OAB and its burden in the United States. The study showed an overall OAB prevalence of 16% with no significant differences between the two sexes. The NOBLE study revealed that specific OAB symptoms were more common in women than in men but with increasing age, especially over the age of 60 years, symptoms were predominant in men.

• #9 Review of the epidemiology of overactive bladder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4902138/

  Although the overall prevalence of OAB is similar between the two sexes, there are sex-specific differences in the prevalence of various symptoms within the OAB complex. […] The EPIC study was a cross-sectional telephone survey of adults aged 18 years. […] The study had 19,000 participants and showed an overall OAB prevalence of 11.8%, with similar rates in men and women. […] The NOBLE program was developed to estimate the prevalence of OAB and its burden in the United States. […] The study showed an overall OAB prevalence of ~16% with no significant differences between the two sexes (16% in men, 16.9% in women). […] The epidemiology of lower urinary tract symptoms (EpiLUTS) survey was a population-based, cross-sectional survey conducted in the US, UK, and Sweden to evaluate the prevalence and bother of OAB.

• #10

  https://link.springer.com/article/10.1007/s00345-002-0301-4

  Context: the National Overactive BLadder Evaluation (NOBLE) Program was initiated to better understand the prevalence and burden of overactive bladder in a broad spectrum of the United States population. […] Objective: to estimate the prevalence of overactive bladder with and without urge incontinence in the US, assess variation in prevalence by sex and other factors, and measure individual burden. […] Results: the overall prevalence of overactive bladder was similar between men (16.0%) and women (16.9%), but sex-specific prevalence differed substantially by severity of symptoms. […] The overall prevalence of overactive bladder does not differ by sex; however, the severity and nature of symptom expression does differ. […] Nonetheless, overactive bladder, with and without incontinence, has a clinically significant impact on quality-of-life, quality-of-sleep, and mental health, in both men and women.

• #11 Review of the epidemiology of overactive bladder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4902138/

  The Milsom study found an overall prevalence of OAB symptoms of 16.6%. […] Multiple studies have assessed the prevalence of OAB and the impact it has on quality of life. […] The prevalence of OAB and its symptoms increases with increasing age in both sexes. […] While the overall prevalence is similar in both sexes, there are some sex-specific differences.

• #12 Review of the epidemiology of overactive bladder | RRU

  https://www.dovepress.com/review-of-the-epidemiology-of-overactive-bladder-peer-reviewed-fulltext-article-RRU

  The epidemiology of lower urinary tract symptoms (EpiLUTS) survey was a population-based, cross-sectional survey conducted in the US, UK, and Sweden to evaluate the prevalence and bother of OAB. The prevalence of OAB depended on how OAB was defined. When symptoms were defined as sometimes, the overall prevalence was 35.6%. When defined as often, the overall prevalence decreased to 24.7%. […] The Milsom study found an overall prevalence of OAB symptoms of 16.6%. Women were slightly more likely than men to report OAB symptoms with the sex-specific prevalence being 15.6% in men and 17.4% in women. The overall prevalence of frequency and urgency was comparable irrespective of sex. However, urge incontinence was found to be more prevalent among women than men. […] Multiple studies have assessed the prevalence of OAB and the impact it has on quality of life. OAB is common in both women and men. The prevalence of OAB and its symptoms increases with increasing age in both sexes. While the overall prevalence is similar in both sexes, there are some sex-specific differences. Urge incontinence is more common in women than in men. OAB in both sexes has a significant impact on the quality of life, quality of sleep, and mental health. Furthermore, the level of bother increases with the number of symptoms experienced. BPH and BOO commonly coexist with OAB and worsen the level of bother and quality of life in men.

• #13 Review of the epidemiology of overactive bladder | RRU

  https://www.dovepress.com/review-of-the-epidemiology-of-overactive-bladder-peer-reviewed-fulltext-article-RRU

  The epidemiology of lower urinary tract symptoms (EpiLUTS) survey was a population-based, cross-sectional survey conducted in the US, UK, and Sweden to evaluate the prevalence and bother of OAB. The prevalence of OAB depended on how OAB was defined. When symptoms were defined as sometimes, the overall prevalence was 35.6%. When defined as often, the overall prevalence decreased to 24.7%. […] The Milsom study found an overall prevalence of OAB symptoms of 16.6%. Women were slightly more likely than men to report OAB symptoms with the sex-specific prevalence being 15.6% in men and 17.4% in women. The overall prevalence of frequency and urgency was comparable irrespective of sex. However, urge incontinence was found to be more prevalent among women than men. […] Multiple studies have assessed the prevalence of OAB and the impact it has on quality of life. OAB is common in both women and men. The prevalence of OAB and its symptoms increases with increasing age in both sexes. While the overall prevalence is similar in both sexes, there are some sex-specific differences. Urge incontinence is more common in women than in men. OAB in both sexes has a significant impact on the quality of life, quality of sleep, and mental health. Furthermore, the level of bother increases with the number of symptoms experienced. BPH and BOO commonly coexist with OAB and worsen the level of bother and quality of life in men.

• #14 Is the Prevalence of Overactive Bladder Overestimated? A Population-Based Study in Finland | PLOS One

  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000195

  In earlier studies, one in six adults had overactive bladder which may impair quality of life. However, earlier studies have either not been population-based or have suffered from methodological limitations. Our aim was to assess the prevalence of overactive bladder symptoms, based on a representative study population and using consistent definitions and exclusions. […] The aim of the study was to assess the age-standardized prevalence of overactive bladder defined as urinary urgency, with or without urgency incontinence, usually with urinary frequency and nocturia in the absence of urinary tract infection or other obvious pathology. […] Our results indicate a prevalence of overactive bladder as low as 8% suggesting that, in previous studies, occurrence has been overestimated due to vague criteria and selected study populations regarding age distribution and low participation.

• #15 Is the Prevalence of Overactive Bladder Overestimated? A Population-Based Study in Finland | PLOS One

  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000195

  Research on urinary storage problems has focused on incontinence in women, but during recent years other urinary storage problems (urgency, frequency, and nocturia) and their treatment among both sexes has commanded attention worldwide. […] The reported prevalence of overactive bladder has varied widely in earlier studies due to differences in symptom assessment, study population, data collection, and definition of overactive bladder including exclusion criteria. […] Several articles have been published on the prevalence of overactive bladder. However, many of these studies have not been population-based, whereas the population-based studies have failed to apply the current definition of overactive bladder, report any exclusions, include all adult ages, include both sexes, report response rate or non-participants, or achieve good response rate. […] Our results suggest that the prevalence of overactive bladder has been overestimated so that the true prevalence is approximately half of that proposed earlier. Overactive bladder affects approximately one out of twelve adults of Caucasian origin.

• #16

  https://link.springer.com/article/10.1007/s00192-024-06029-2

  Our investigation also revealed that the prevalence among individuals aged 60 years and older was higher than that of other age cohorts, standing at 28.3% (95% CI 0.240.33). […] Additionally, the prevalence in LMIC countries was higher than in UMIC and HIC countries, at 27.4% (95% CI 0.140.40), but without statistical significance. Over time, the global prevalence of OAB has generally increased, rising from 18.1% (95% CI 0.130.23) in 2000-2005 to 23.9% (95% CI 0.190.29) in 2021-2024. […] This study underscores the substantial public health challenge presented by OAB on a global scale. Primarily, obesity, gender, and age emerge as predisposing factors for OAB. Over the past two decades, there has been a rising trend in OAB prevalence.

• #17 Prevalence and trends in overactive bladder among men in the United States, 2005–2020 | Scientific Reports

  https://www.nature.com/articles/s41598-024-66758-8

  The purpose of present study was to examine the current prevalence and recent trends of overactive bladder (OAB) among US adult men and examine the correlations between OAB and several potential risk factors. […] The overall prevalence of OAB increased slightly from 11.3% in 2005-2008 to 11.7% in 2009-2014 and significantly increased to 14.5% in 2015-2020. […] The contemporary prevalence of OAB was high, affecting 14.5% US men and the estimated overall prevalence significantly increased from 2005 to 2020. […] Data on the epidemiology of male OAB are scarce. […] The contemporary prevalence and recent trends in male OAB were unknown. […] The present study, for the first time, systematically evaluated nearly 20-year trend in OAB among US men. […] The prevalence and trends of OAB were found to be associated with some sociodemographic features.

• #18 Prevalence and trends in overactive bladder among men in the United States, 2005–2020 | Scientific Reports

  https://www.nature.com/articles/s41598-024-66758-8

  Chronic comorbidities, diabetes, stroke or cancer, were all associated with a higher prevalence with OAB. […] The NHANES design constituted the principal strengths of this study. […] The present study provided crucial observations of contemporary epidemiology of OAB, and disparities of OAB in sociodemographic, comorbidities and lifestyles, which may inform future studies and public health planning. […] The overall prevalence of OAB significantly increased across recent two decades, especially among men who were aged 40-59 years, non-Hispanic White and Black, and overweight and obese men.

• #19 Review of the epidemiology of overactive bladder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4902138/

  Although the overall prevalence of OAB is similar between the two sexes, there are sex-specific differences in the prevalence of various symptoms within the OAB complex. […] The EPIC study was a cross-sectional telephone survey of adults aged 18 years. […] The study had 19,000 participants and showed an overall OAB prevalence of 11.8%, with similar rates in men and women. […] The NOBLE program was developed to estimate the prevalence of OAB and its burden in the United States. […] The study showed an overall OAB prevalence of ~16% with no significant differences between the two sexes (16% in men, 16.9% in women). […] The epidemiology of lower urinary tract symptoms (EpiLUTS) survey was a population-based, cross-sectional survey conducted in the US, UK, and Sweden to evaluate the prevalence and bother of OAB.

• #20 Review of the epidemiology of overactive bladder | RRU

  https://www.dovepress.com/review-of-the-epidemiology-of-overactive-bladder-peer-reviewed-fulltext-article-RRU

  Overactive bladder (OAB) is common in both men and women. It is a symptom complex that causes significant detriment to quality of life in patients. Although the prevalence of OAB is similar in both sexes, there are sex-specific differences in individual symptoms and the impact on quality of life. This review examines the major studies that looked at the epidemiology of OAB as it relates to both sexes. It focuses on both the overall prevalence rates and the incidence of individual symptoms. This paper also addresses the level of bother and quality of life in men and women with OAB. […] Overactive bladder (OAB) is a prevalent condition in both men and women. It may have a significant impact on overall quality of life, sexual function, sleep, and mental health. According to the International Continence Society (ICS) definition, OAB consists of urinary urgency with or without urge incontinence, often accompanied by frequency and nocturia. Numerous publications have studied the prevalence of OAB in developed countries and assessed the impact it has on quality of life with various results. Although the overall prevalence of OAB is similar between the two sexes, there are sex-specific differences in the prevalence of various symptoms within the OAB complex.

• #21 Overactive Bladder: Practice Essentials, Background, Anatomy and Physiology

  https://emedicine.medscape.com/article/459340-overview

  In the NOBLE study, the prevalence of OAB was similar in women and men (16.9% and 16%, respectively). However, the prevalence of incontinence associated with OAB differed. Among women, 9.3% reported having OAB with incontinence; 7.6% reported having OAB without incontinence. In contrast, more men reported having OAB without incontinence (13.4%) than with incontinence (2.6%). In women, the prevalence of OAB with urgency urinary incontinence increased with increasing body mass index (BMI), whereas in men, no difference was found. […] Milsom et al, in a population-based survey (conducted by telephone or direct interview) of 16,776 men and women aged 40 years or older from the general population in Europe, found the overall prevalence of OAB symptoms to be 16.6%. The main outcome measures included the prevalence of urinary frequency (8 micturitions per day), urinary urgency, and urgency incontinence.

• #22 Prevalence and bother of lower urinary tract symptoms and overactive bladder in Poland, an Eastern European Study | Scientific Reports

  https://www.nature.com/articles/s41598-020-76846-0

  The prevalence of lower urinary tract symptoms (LUTS) and overactive bladder (OAB) has been measured by population-based investigations in many parts of the world. However, data are lacking for Eastern Europe, and there has not been any large population-representative study in any country of this region. […] The prevalence of LUTS was 69.8% (men 66.2%; women 72.6%). […] The prevalence of OAB was higher in women (39.5%) than in men (26.8%), and OAB increased with age. […] This investigation was the first nationwide, population-representative epidemiological study of LUTS and OAB in an Eastern-European country. […] The prevalence of LUTS has been estimated in several large population-based studies from various regions of the world. […] Our observation (n=6005) of LUTS in 69.8% of adults aged 40, affecting more women than men, appears broadly comparable with data from population-based studies performed in other countries and regions.

• #23 Review of the epidemiology of overactive bladder | RRU

  https://www.dovepress.com/review-of-the-epidemiology-of-overactive-bladder-peer-reviewed-fulltext-article-RRU

  The epidemiology of lower urinary tract symptoms (EpiLUTS) survey was a population-based, cross-sectional survey conducted in the US, UK, and Sweden to evaluate the prevalence and bother of OAB. The prevalence of OAB depended on how OAB was defined. When symptoms were defined as sometimes, the overall prevalence was 35.6%. When defined as often, the overall prevalence decreased to 24.7%. […] The Milsom study found an overall prevalence of OAB symptoms of 16.6%. Women were slightly more likely than men to report OAB symptoms with the sex-specific prevalence being 15.6% in men and 17.4% in women. The overall prevalence of frequency and urgency was comparable irrespective of sex. However, urge incontinence was found to be more prevalent among women than men. […] Multiple studies have assessed the prevalence of OAB and the impact it has on quality of life. OAB is common in both women and men. The prevalence of OAB and its symptoms increases with increasing age in both sexes. While the overall prevalence is similar in both sexes, there are some sex-specific differences. Urge incontinence is more common in women than in men. OAB in both sexes has a significant impact on the quality of life, quality of sleep, and mental health. Furthermore, the level of bother increases with the number of symptoms experienced. BPH and BOO commonly coexist with OAB and worsen the level of bother and quality of life in men.

• #24 Review of the epidemiology of overactive bladder | RRU

  https://www.dovepress.com/review-of-the-epidemiology-of-overactive-bladder-peer-reviewed-fulltext-article-RRU

  The epidemiology of lower urinary tract symptoms (EpiLUTS) survey was a population-based, cross-sectional survey conducted in the US, UK, and Sweden to evaluate the prevalence and bother of OAB. The prevalence of OAB depended on how OAB was defined. When symptoms were defined as sometimes, the overall prevalence was 35.6%. When defined as often, the overall prevalence decreased to 24.7%. […] The Milsom study found an overall prevalence of OAB symptoms of 16.6%. Women were slightly more likely than men to report OAB symptoms with the sex-specific prevalence being 15.6% in men and 17.4% in women. The overall prevalence of frequency and urgency was comparable irrespective of sex. However, urge incontinence was found to be more prevalent among women than men. […] Multiple studies have assessed the prevalence of OAB and the impact it has on quality of life. OAB is common in both women and men. The prevalence of OAB and its symptoms increases with increasing age in both sexes. While the overall prevalence is similar in both sexes, there are some sex-specific differences. Urge incontinence is more common in women than in men. OAB in both sexes has a significant impact on the quality of life, quality of sleep, and mental health. Furthermore, the level of bother increases with the number of symptoms experienced. BPH and BOO commonly coexist with OAB and worsen the level of bother and quality of life in men.

• #25 The AUA/SUFU Guideline on the Diagnosis and Treatment of Idiopathic Overactive Bladder – American Urological Association

  https://www.auanet.org/guidelines-and-quality/guidelines/idiopathic-overactive-bladder

  In population-based studies, OAB prevalence rates range from 7% to 27% in men, and 9% to 43% in women. No clear differences exist between studies conducted in North America versus other populations. Some studies report higher prevalence rates in women than men, while others found similar rates across genders. However, UUI is consistently more common in women than in men. OAB symptom prevalence and severity tend to increase with age. A proportion of OAB cases (37-39%) remit during a given year, but the majority of patients have symptoms for years. To date, few population-based studies have been published directly examining epidemiologic differences across racial/ethnic groups and there is even less data on gender diverse groups. Data from the Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium’s RISE FOR HEALTH Study will be available later this year and will provide contemporary prevalence estimates for OAB and other lower urinary tract symptoms (LUTS) in an ethnically and racially diverse sample of US women aged 18-100 years. It will further inform the concept of bladder health which goes beyond OAB/LUTS to encompass the physical, mental, and social well-being related to the bladder. The study will explore novel risk and protective factors and adaptive behaviors women use to manage their bladders to further advance OAB/LUTS prevention efforts.

• #26 Review of the epidemiology of overactive bladder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4902138/

  The Milsom study found an overall prevalence of OAB symptoms of 16.6%. […] Multiple studies have assessed the prevalence of OAB and the impact it has on quality of life. […] The prevalence of OAB and its symptoms increases with increasing age in both sexes. […] While the overall prevalence is similar in both sexes, there are some sex-specific differences.

• #27 Review of the epidemiology of overactive bladder | RRU

  https://www.dovepress.com/review-of-the-epidemiology-of-overactive-bladder-peer-reviewed-fulltext-article-RRU

  The epidemiology of lower urinary tract symptoms (EpiLUTS) survey was a population-based, cross-sectional survey conducted in the US, UK, and Sweden to evaluate the prevalence and bother of OAB. The prevalence of OAB depended on how OAB was defined. When symptoms were defined as sometimes, the overall prevalence was 35.6%. When defined as often, the overall prevalence decreased to 24.7%. […] The Milsom study found an overall prevalence of OAB symptoms of 16.6%. Women were slightly more likely than men to report OAB symptoms with the sex-specific prevalence being 15.6% in men and 17.4% in women. The overall prevalence of frequency and urgency was comparable irrespective of sex. However, urge incontinence was found to be more prevalent among women than men. […] Multiple studies have assessed the prevalence of OAB and the impact it has on quality of life. OAB is common in both women and men. The prevalence of OAB and its symptoms increases with increasing age in both sexes. While the overall prevalence is similar in both sexes, there are some sex-specific differences. Urge incontinence is more common in women than in men. OAB in both sexes has a significant impact on the quality of life, quality of sleep, and mental health. Furthermore, the level of bother increases with the number of symptoms experienced. BPH and BOO commonly coexist with OAB and worsen the level of bother and quality of life in men.

• #28 Volume 1, Chapter 88. The Overactive Bladder

  https://m.glowm.com/resources/glowm/cd/pages/v1/v1c088.html

  The National Overactive Bladder Evaluation (NOBLE) Program was established to provide an estimate of the prevalence and burden of illness of OAB in the United States. The prevalence of OAB was 16.9% in women and 16% in men, increasing with age. OAB dry and wet occurred in 7.6% and 9.3% of women interviewed, respectively. Across the United States, these figures would estimate 33.3 million adults with OAB, of whom 12.2 million would have incontinence. The prevalence was noted to be small in both sexes until approximately age 60 years in women (12%); however, it then increased to 20% at age 65 years or older. […] While the two aforementioned telephone surveys may be criticized on the basis of methodology, they present a significant advance in the understanding of OAB and its impact on daily life.

• #29 Overactive Bladder: Practice Essentials, Background, Anatomy and Physiology

  https://emedicine.medscape.com/article/459340-overview

  In the National Overactive Bladder Evaluation (NOBLE) study, which evaluated 5204 adults 18 years of age and older who were representative of the US population by sex, age, and geographical region, 16.5% of the study participants met the criteria for OAB. Of those, 6.1% met the criteria for OAB with urgency incontinence, and 10.4% met criteria for OAB without urgency incontinence. Among individuals with OAB with urgency incontinence, 45% had mixed incontinence symptoms (urgency incontinence plus stress incontinence). Data in the study were gathered with the use of a computer-assisted telephone interview questionnaire. […] OAB affects millions of people worldwide, regardless of race. The frequency data on OAB found in Europe are similar to that found in the United States. […] The prevalence of OAB increases with age. However, OAB should not be considered a normal part of aging. Twenty percent of the population aged 70 years or older report symptoms of OAB; 30% of those aged 75 years or older report symptoms. Men tend to develop OAB slightly later in life than women do.

• #30

  https://link.springer.com/article/10.1007/s00192-024-06029-2

  Our investigation also revealed that the prevalence among individuals aged 60 years and older was higher than that of other age cohorts, standing at 28.3% (95% CI 0.240.33). […] Additionally, the prevalence in LMIC countries was higher than in UMIC and HIC countries, at 27.4% (95% CI 0.140.40), but without statistical significance. Over time, the global prevalence of OAB has generally increased, rising from 18.1% (95% CI 0.130.23) in 2000-2005 to 23.9% (95% CI 0.190.29) in 2021-2024. […] This study underscores the substantial public health challenge presented by OAB on a global scale. Primarily, obesity, gender, and age emerge as predisposing factors for OAB. Over the past two decades, there has been a rising trend in OAB prevalence.

• #31 Review of the epidemiology of overactive bladder | RRU

  https://www.dovepress.com/review-of-the-epidemiology-of-overactive-bladder-peer-reviewed-fulltext-article-RRU

  This is one of the largest population-based surveys that studied the prevalence of lower urinary tract symptoms (LUTS) and OAB. The EPIC study showed an overall OAB prevalence of 11.8%, with similar rates in men and women. The EPIC study showed that the prevalence of LUTS suggestive of OAB was 10.8% in men and 12.8% in women. It can be seen from the EPIC study that the incidence of LUTS in general was similar but slightly more common in women than in men. […] The NOBLE program was developed to estimate the prevalence of OAB and its burden in the United States. The study showed an overall OAB prevalence of 16% with no significant differences between the two sexes. The NOBLE study revealed that specific OAB symptoms were more common in women than in men but with increasing age, especially over the age of 60 years, symptoms were predominant in men.

• #32 Review of the epidemiology of overactive bladder | RRU

  https://www.dovepress.com/review-of-the-epidemiology-of-overactive-bladder-peer-reviewed-fulltext-article-RRU

  The epidemiology of lower urinary tract symptoms (EpiLUTS) survey was a population-based, cross-sectional survey conducted in the US, UK, and Sweden to evaluate the prevalence and bother of OAB. The prevalence of OAB depended on how OAB was defined. When symptoms were defined as sometimes, the overall prevalence was 35.6%. When defined as often, the overall prevalence decreased to 24.7%. […] The Milsom study found an overall prevalence of OAB symptoms of 16.6%. Women were slightly more likely than men to report OAB symptoms with the sex-specific prevalence being 15.6% in men and 17.4% in women. The overall prevalence of frequency and urgency was comparable irrespective of sex. However, urge incontinence was found to be more prevalent among women than men. […] Multiple studies have assessed the prevalence of OAB and the impact it has on quality of life. OAB is common in both women and men. The prevalence of OAB and its symptoms increases with increasing age in both sexes. While the overall prevalence is similar in both sexes, there are some sex-specific differences. Urge incontinence is more common in women than in men. OAB in both sexes has a significant impact on the quality of life, quality of sleep, and mental health. Furthermore, the level of bother increases with the number of symptoms experienced. BPH and BOO commonly coexist with OAB and worsen the level of bother and quality of life in men.

• #33

  https://link.springer.com/article/10.1007/s00192-024-06029-2

  This study aims to systematically estimate the global prevalence of overactive bladder (OAB), identify demographic and regional factors contributing to prevalence variations, and assess trends in prevalence over the past two decades. […] A total of 53 studies, encompassing 610,438 participants, were ultimately included in the analysis. The meta-analysis determined the global prevalence of OAB to be 20% (95% CI 0.180.21). Over the past 20 years, there has been an increase in OAB prevalence, rising from 18.1% (95% CI 0.130.23) to 23.9% (95% CI 0.190.29). […] The study highlights higher risks of OAB among obese individuals, women, and the elderly. OAB prevalence has shown an increasing trend over the past 20 years. […] Despite the extensive impact of OAB, its prevalence varies widely among countries and regions. Large-scale epidemiologic studies report prevalence rates ranging from 8.8% in China to 23.2% in the United States.

• #34 Volume 1, Chapter 88. The Overactive Bladder

  https://www.glowm.com/resources/glowm/cd/pages/v1/v1c088.html

  The overactive bladder and associated urinary incontinence affects 17 million Americans at a cost of $26 billion annually, mostly for pads, diapers, and other temporizing measures. Among the elderly, 15% to 30% of those living at home and 30% to 50% of those in assisted living situations, acute-care facilities, or nursing homes are affected. Despite a prevalence greater than other chronic diseases, such as asthma and coronary artery disease, our understanding of the problem is quite limited. […] The currently reported median prevalence of incontinence in women varies from 14% to 40.5% (by the ICS definition 23.5%). Milsom and associates reported a study performed in France, Germany, Italy, Sweden, and the United Kingdom. Frequency caused by OAB was defined as more than eight micturitions in 24 hours and nocturia more than two micturitions at night. Of the 16,776 respondents, 19% reported current bladder symptoms and 17% had symptoms of OAB. Prevalence varied by country from 20% of women in Spain to 13% in France. Seventy-nine percent of patients had symptoms for more than 1 year and 49% had symptoms for more than 3 years. Frequency (85%) was the most common symptom, followed by urgency (54%) and urge incontinence (36%). The prevalence of symptoms increased with age, as shown in Table 2.

• #35

  https://link.springer.com/article/10.1007/s00192-024-06029-2

  This study aims to systematically estimate the global prevalence of overactive bladder (OAB), identify demographic and regional factors contributing to prevalence variations, and assess trends in prevalence over the past two decades. […] A total of 53 studies, encompassing 610,438 participants, were ultimately included in the analysis. The meta-analysis determined the global prevalence of OAB to be 20% (95% CI 0.180.21). Over the past 20 years, there has been an increase in OAB prevalence, rising from 18.1% (95% CI 0.130.23) to 23.9% (95% CI 0.190.29). […] The study highlights higher risks of OAB among obese individuals, women, and the elderly. OAB prevalence has shown an increasing trend over the past 20 years. […] Despite the extensive impact of OAB, its prevalence varies widely among countries and regions. Large-scale epidemiologic studies report prevalence rates ranging from 8.8% in China to 23.2% in the United States.

• #36

  https://www.archivesofmedicalscience.com/Effects-of-overactive-bladder-on-treatment-related-nbehaviour-and-quality-of-life,133119,0,2.html

  The aim of this study was to investigate treatment-related behaviour and quality of life of a Polish population that reported symptoms of overactive bladder (OAB) syndrome. […] Of 6005 participants, 33.9% (n = 2041) had a possible diagnosis of OAB. Almost 40% (n = 810) were seeking treatment, and most participants received treatment (37.7%, n = 770). […] Finally, OAB had a negative effect on quality of life because 43% (n = 878) of persons with possible OAB had concerns about their quality of life related to their urinary condition. […] This study is the first Eastern European population-representative analysis of treatment-related behaviours for OAB.

• #37 Epidemiology, prescribing patterns and resource use associated with overactive bladder in UK primary care. — Nuffield Department of Population Health

  https://www.ndph.ox.ac.uk/publications/162648

  This study aimed to estimate the incidence and prevalence of overactive bladder (OAB) symptoms in the UK and analyse the use of anticholinergic/antispasmodic medications and other healthcare resources within UK general practice. […] The overall prevalence of OAB-related symptoms was 3.87 per 1000 persons, with an incidence of 2.79 per 1000 person-years. […] In conclusion, this study suggests that OAB may be under-diagnosed in the UK and that current guidelines recommending use of anticholinergic medication, continence nurse consultations and urinary tests/investigations are inadequately followed.

• #38 Overactive bladder syndrome: Management and treatment options

  https://www1.racgp.org.au/ajgp/2020/september/overactive-bladder-syndrome

  Overactive bladder (OAB) is a common syndrome in the community characterised by unstable bladder contractions, resulting in urinary urgency, frequency and nocturia in the absence of detectable disease. Large studies suggest that 10% of the general population is symptomatic. […] The associated sequelae of OAB, including urinary incontinence, have a negative impact on the quality of life of affected individuals. […] OAB is a common syndrome in the Australian community. It adversely affects the elderly and is debilitating for patients physically, psychologically and socially. […] The definition of OAB is symptom based, and a diagnosis is made in the absence of an identifiable disease. […] OAB is a common condition in Australia that disproportionately affects the elderly.

• #39 Risk Factors for Overactive Bladder and Urinary Incontinence – Cancer Therapy Advisor

  https://www.cancertherapyadvisor.com/home/tools/clinical-charts/risk-factors-for-overactive-bladder-and-urinary-incontinence/

  Men 65yrs of age and older, the prevalence increased to 8.2% (6574yrs) and 10.2% (75yrs) [NOBLE study]. […] Prevalence of OAB with urge incontinence increased with age from 2% (1824yrs) to 19.1% (6574yrs) in women, with a marked increase after 44yrs of age [NOBLE study]. […] The prevalence of OAB is 33.3% in African American (AA) men, 28% in Hispanic, 27% in Asian, and 26.3% in white men (EpiLUTS study). […] The prevalence of OAB is 45.9% in AA women, 43.4% in white, 42% in Hispanic, and 26.6% in Asian women (EpiLUTS study). […] NHANES data on UI supports that AA women report the highest prevalence of urge-UI (11%) over white (7.5%) and Mexican-American (7.5%) women.

• #40 Risk Factors for Overactive Bladder and Urinary Incontinence – Cancer Therapy Advisor

  https://www.cancertherapyadvisor.com/home/tools/clinical-charts/risk-factors-for-overactive-bladder-and-urinary-incontinence/

  Men 65yrs of age and older, the prevalence increased to 8.2% (6574yrs) and 10.2% (75yrs) [NOBLE study]. […] Prevalence of OAB with urge incontinence increased with age from 2% (1824yrs) to 19.1% (6574yrs) in women, with a marked increase after 44yrs of age [NOBLE study]. […] The prevalence of OAB is 33.3% in African American (AA) men, 28% in Hispanic, 27% in Asian, and 26.3% in white men (EpiLUTS study). […] The prevalence of OAB is 45.9% in AA women, 43.4% in white, 42% in Hispanic, and 26.6% in Asian women (EpiLUTS study). […] NHANES data on UI supports that AA women report the highest prevalence of urge-UI (11%) over white (7.5%) and Mexican-American (7.5%) women.

• #41 Review of the epidemiology of overactive bladder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4902138/

  The Milsom study found an overall prevalence of OAB symptoms of 16.6%. […] Multiple studies have assessed the prevalence of OAB and the impact it has on quality of life. […] The prevalence of OAB and its symptoms increases with increasing age in both sexes. […] While the overall prevalence is similar in both sexes, there are some sex-specific differences.

• #42 Overactive Bladder: Practice Essentials, Background, Anatomy and Physiology

  https://emedicine.medscape.com/article/459340-overview

  In the NOBLE study, the prevalence of OAB was similar in women and men (16.9% and 16%, respectively). However, the prevalence of incontinence associated with OAB differed. Among women, 9.3% reported having OAB with incontinence; 7.6% reported having OAB without incontinence. In contrast, more men reported having OAB without incontinence (13.4%) than with incontinence (2.6%). In women, the prevalence of OAB with urgency urinary incontinence increased with increasing body mass index (BMI), whereas in men, no difference was found. […] Milsom et al, in a population-based survey (conducted by telephone or direct interview) of 16,776 men and women aged 40 years or older from the general population in Europe, found the overall prevalence of OAB symptoms to be 16.6%. The main outcome measures included the prevalence of urinary frequency (8 micturitions per day), urinary urgency, and urgency incontinence.

• #43

  https://journals.lww.com/co-obgyn/fulltext/2005/10000/overactive_bladder__epidemiology_and_social_impact.11.aspx?generateEpub=Article%7Cco-obgyn:2005:10000:00011%7C10.1097/01.gco.0000183529.26352.52%7C

  Overactive bladder epidemiology is a rapidly evolving field. The new terminology of lower urinary tract function, introduced in 2002, modified the definitions of all four components of overactive bladder. In the same year, the lack of specific information on overactive bladder prevalence was identified and consequently new studies were launched and recently published. […] Studies conducted in selected countries and populations suggested comparable prevalence data worldwide, although the syndrome is considered to be underreported. […] Recent epidemiological data confirm the increase in overactive bladder prevalence with age and suggest that most diet and lifestyle factors are not associated with the condition, with the exception of body mass index. […] The socioeconomic consequences of the overactive bladder syndrome were recently estimated in a large US study and a total cost of US$12.6 billion was calculated. […] Specific data on overactive bladder epidemiology are now available, providing new evidence about its relevance as a clinical issue.

• #44 Overactive Bladder: Practice Essentials, Background, Anatomy and Physiology

  https://emedicine.medscape.com/article/459340-overview

  In the NOBLE study, the prevalence of OAB was similar in women and men (16.9% and 16%, respectively). However, the prevalence of incontinence associated with OAB differed. Among women, 9.3% reported having OAB with incontinence; 7.6% reported having OAB without incontinence. In contrast, more men reported having OAB without incontinence (13.4%) than with incontinence (2.6%). In women, the prevalence of OAB with urgency urinary incontinence increased with increasing body mass index (BMI), whereas in men, no difference was found. […] Milsom et al, in a population-based survey (conducted by telephone or direct interview) of 16,776 men and women aged 40 years or older from the general population in Europe, found the overall prevalence of OAB symptoms to be 16.6%. The main outcome measures included the prevalence of urinary frequency (8 micturitions per day), urinary urgency, and urgency incontinence.

• #45 Prevalence and trends in overactive bladder among men in the United States, 2005–2020 | Scientific Reports

  https://www.nature.com/articles/s41598-024-66758-8

  Chronic comorbidities, diabetes, stroke or cancer, were all associated with a higher prevalence with OAB. […] The NHANES design constituted the principal strengths of this study. […] The present study provided crucial observations of contemporary epidemiology of OAB, and disparities of OAB in sociodemographic, comorbidities and lifestyles, which may inform future studies and public health planning. […] The overall prevalence of OAB significantly increased across recent two decades, especially among men who were aged 40-59 years, non-Hispanic White and Black, and overweight and obese men.

• #46 The prevalence of probable overactive bladder and associated risk factors among medical students in Jordan: a cross-sectional study | BMC Urology | Full Text

  https://bmcurol.biomedcentral.com/articles/10.1186/s12894-023-01394-4

  Our study has also revealed that OAB was substantially more prevalent in basic years medical students than in clinical years (OR=2.165). […] The intricate relationship between psychological stress and overactive bladder (OAB) symptoms unfolds through a complex interplay of stress-induced hormonal responses. […] Our study found an association between stress experienced by medical students during the course of their studies and the prevalence of OAB among them (P-value=0.004). […] Our study found a link between a history of UTI and OAB (P value=0.003). […] In our study, OAB symptoms were shown to be more common in medical students with a history of recent trauma (OR=1.82%). […] OAB symptoms were shown to be more common among medical students who took alpha-blockers, sedative-hypnotics, antidepressants, antipsychotics, ACE inhibitors, loop diuretics, and nonsteroidal anti-inflammatory medicines (OR=2.1). […] The study findings suggest that OABSS was more common among younger students and those in their early years of medical education. […] The presence of risk factors such as a recent history of UTI, trauma, and high stress was significantly associated with the development of OAB symptoms.

• #47 The prevalence of probable overactive bladder and associated risk factors among medical students in Jordan: a cross-sectional study | BMC Urology | Full Text

  https://bmcurol.biomedcentral.com/articles/10.1186/s12894-023-01394-4

  Our study has also revealed that OAB was substantially more prevalent in basic years medical students than in clinical years (OR=2.165). […] The intricate relationship between psychological stress and overactive bladder (OAB) symptoms unfolds through a complex interplay of stress-induced hormonal responses. […] Our study found an association between stress experienced by medical students during the course of their studies and the prevalence of OAB among them (P-value=0.004). […] Our study found a link between a history of UTI and OAB (P value=0.003). […] In our study, OAB symptoms were shown to be more common in medical students with a history of recent trauma (OR=1.82%). […] OAB symptoms were shown to be more common among medical students who took alpha-blockers, sedative-hypnotics, antidepressants, antipsychotics, ACE inhibitors, loop diuretics, and nonsteroidal anti-inflammatory medicines (OR=2.1). […] The study findings suggest that OABSS was more common among younger students and those in their early years of medical education. […] The presence of risk factors such as a recent history of UTI, trauma, and high stress was significantly associated with the development of OAB symptoms.

• #48 The prevalence of probable overactive bladder and associated risk factors among medical students in Jordan: a cross-sectional study | BMC Urology | Full Text

  https://bmcurol.biomedcentral.com/articles/10.1186/s12894-023-01394-4

  Our study has also revealed that OAB was substantially more prevalent in basic years medical students than in clinical years (OR=2.165). […] The intricate relationship between psychological stress and overactive bladder (OAB) symptoms unfolds through a complex interplay of stress-induced hormonal responses. […] Our study found an association between stress experienced by medical students during the course of their studies and the prevalence of OAB among them (P-value=0.004). […] Our study found a link between a history of UTI and OAB (P value=0.003). […] In our study, OAB symptoms were shown to be more common in medical students with a history of recent trauma (OR=1.82%). […] OAB symptoms were shown to be more common among medical students who took alpha-blockers, sedative-hypnotics, antidepressants, antipsychotics, ACE inhibitors, loop diuretics, and nonsteroidal anti-inflammatory medicines (OR=2.1). […] The study findings suggest that OABSS was more common among younger students and those in their early years of medical education. […] The presence of risk factors such as a recent history of UTI, trauma, and high stress was significantly associated with the development of OAB symptoms.

• #49 Review of the epidemiology of overactive bladder | RRU

  https://www.dovepress.com/review-of-the-epidemiology-of-overactive-bladder-peer-reviewed-fulltext-article-RRU

  The epidemiology of lower urinary tract symptoms (EpiLUTS) survey was a population-based, cross-sectional survey conducted in the US, UK, and Sweden to evaluate the prevalence and bother of OAB. The prevalence of OAB depended on how OAB was defined. When symptoms were defined as sometimes, the overall prevalence was 35.6%. When defined as often, the overall prevalence decreased to 24.7%. […] The Milsom study found an overall prevalence of OAB symptoms of 16.6%. Women were slightly more likely than men to report OAB symptoms with the sex-specific prevalence being 15.6% in men and 17.4% in women. The overall prevalence of frequency and urgency was comparable irrespective of sex. However, urge incontinence was found to be more prevalent among women than men. […] Multiple studies have assessed the prevalence of OAB and the impact it has on quality of life. OAB is common in both women and men. The prevalence of OAB and its symptoms increases with increasing age in both sexes. While the overall prevalence is similar in both sexes, there are some sex-specific differences. Urge incontinence is more common in women than in men. OAB in both sexes has a significant impact on the quality of life, quality of sleep, and mental health. Furthermore, the level of bother increases with the number of symptoms experienced. BPH and BOO commonly coexist with OAB and worsen the level of bother and quality of life in men.

• #50 Overactive Bladder (OAB): Symptoms and Treatment

  https://patient.info/doctor/overactive-bladder

  OAB is the second most common cause of female urinary incontinence (stress incontinence is the most common). […] The prevalence of OAB increases with age. […] OAB may be associated with Parkinson’s disease, spinal cord injury, diabetic neuropathy, multiple sclerosis, dementia or stroke; however, most cases have no specific cause. […] In men, urge incontinence may be due to neurological disease or an enlarged prostate gland (benign prostatic hypertrophy or prostate cancer).

• #51 The prevalence of probable overactive bladder and associated risk factors among medical students in Jordan: a cross-sectional study | BMC Urology | Full Text

  https://bmcurol.biomedcentral.com/articles/10.1186/s12894-023-01394-4

  Overactive bladder symptoms were also prevalent among medical and dentistry students across Palestinian universities and a study showed that 35.4% of Turkish midwifery students have probable overactive bladder. […] Common medical disease like hypertension, diabetes mellitus and hyperlipidemia, operation history, smoking and overweight (body mass index [BMI]=25) are considered as significant risk factors of overactive bladder. […] According to cohort study the overall incidence of psychiatric disorders in the OAB exposed group was 41.7% higher than in the non-OAB unexposed group. […] Our study found an association between stress experienced by medical students during the course of their studies and the prevalence of OAB among them (P-value=0.004). […] This is in accordance with the findings of numerous prior studies.

• #52 Sleep Disorder in Children With Overactive Bladder | Yousefichaijan | International Journal of Clinical Pediatrics

  https://www.theijcp.org/index.php/ijcp/article/view/212/161

  According to the results, significant difference was found between the case patients and control subjects in terms of primary sleep disorders, primary hypersomnia and sleep terror disorders. […] According to the results of the present study, significant differences were discovered between children with and without overactive bladders in terms of primary insomnia, hypersomnia disorders, circadian rhythm sleep disorders and sleep terror disorders.

• #53 Prevalence of Overactive Bladder Symptoms Among Women with Interstitial Cystitis/Bladder Pain Syndrome

  https://stacks.cdc.gov/view/cdc/115503

  Importance: Symptoms of urinary frequency, urgency, and urinary leakage are characteristic of overactive bladder syndrome. […] Objective: Our objective was to describe the urge incontinence among women with IC/BPS, which may indicate true overlap of OAB and IC/BPS. […] Results: Within the cohort of 144 women with IC/BPS, 100 (69%) had urinary leakage associated with the strong desire to void, and more likely to have incontinence compared to healthy controls (p […] Conclusions: The prevalence of OAB symptoms of urinary leakage is high among women with IC/BPS. This may explain the efficacy of OAB medication and third-line therapies in this population.

• #54

  https://www.ics.org/2024/abstract/802

  The overall prevalences of COUB, OAB, UAB, and non-OAB/UAB were 4.3% (n = 135), 9.6% (n = 299), 5.0% (n = 155), and 81.1% (n = 2533) in men, and 1.6% (n = 50), 8.2% (n = 254), 2.4% (n = 73), and 87.8% (n = 2711) in women, respectively. The prevalence of all categories significantly increased with age. The overall prevalence of COUB in the OAB population was 31.1% (135/434) and 16.4% (50/304) in men and women, respectively, and significantly increased with age only in women. The overall prevalence of COUB in the UAB population was 46.6% (135/290) and 40.7% (50/123) in men and women, respectively, which significantly increased with age only in women. In the COUB population, the impact on QOL rated as slight or more and the proportion of physician visits was the highest among the groups. […] The prevalence of COUB increased with age. However, the prevalence of COUB with age in the OAB and UAB population differed between men and women. This suggests that gender differences should be kept in mind when considering the pathophysiology of COUB. Consistent with the results of EPIC study, COUB adversely affects participants QOL to a substantial degree, which should be associated with the higher physician visit rate than in other groups. In this large-scale cross-sectional study, the prevalence of COUB increased with age, but certain gender differences may exist. Further longitudinal studies focusing not only on OAB but also on UAB are required to elucidate the precise epidemiological aspects of COUB. This study highlighted that COUB deteriorated QOL more profoundly than OAB or UAB alone, promoting the health-care seeking behavior of the participants.

• #55

  https://link.springer.com/article/10.1007/s00345-002-0301-4

  Context: the National Overactive BLadder Evaluation (NOBLE) Program was initiated to better understand the prevalence and burden of overactive bladder in a broad spectrum of the United States population. […] Objective: to estimate the prevalence of overactive bladder with and without urge incontinence in the US, assess variation in prevalence by sex and other factors, and measure individual burden. […] Results: the overall prevalence of overactive bladder was similar between men (16.0%) and women (16.9%), but sex-specific prevalence differed substantially by severity of symptoms. […] The overall prevalence of overactive bladder does not differ by sex; however, the severity and nature of symptom expression does differ. […] Nonetheless, overactive bladder, with and without incontinence, has a clinically significant impact on quality-of-life, quality-of-sleep, and mental health, in both men and women.

• #56 Review of the epidemiology of overactive bladder | RRU

  https://www.dovepress.com/review-of-the-epidemiology-of-overactive-bladder-peer-reviewed-fulltext-article-RRU

  The epidemiology of lower urinary tract symptoms (EpiLUTS) survey was a population-based, cross-sectional survey conducted in the US, UK, and Sweden to evaluate the prevalence and bother of OAB. The prevalence of OAB depended on how OAB was defined. When symptoms were defined as sometimes, the overall prevalence was 35.6%. When defined as often, the overall prevalence decreased to 24.7%. […] The Milsom study found an overall prevalence of OAB symptoms of 16.6%. Women were slightly more likely than men to report OAB symptoms with the sex-specific prevalence being 15.6% in men and 17.4% in women. The overall prevalence of frequency and urgency was comparable irrespective of sex. However, urge incontinence was found to be more prevalent among women than men. […] Multiple studies have assessed the prevalence of OAB and the impact it has on quality of life. OAB is common in both women and men. The prevalence of OAB and its symptoms increases with increasing age in both sexes. While the overall prevalence is similar in both sexes, there are some sex-specific differences. Urge incontinence is more common in women than in men. OAB in both sexes has a significant impact on the quality of life, quality of sleep, and mental health. Furthermore, the level of bother increases with the number of symptoms experienced. BPH and BOO commonly coexist with OAB and worsen the level of bother and quality of life in men.

• #57

  https://www.archivesofmedicalscience.com/Effects-of-overactive-bladder-on-treatment-related-nbehaviour-and-quality-of-life,133119,0,2.html

  The aim of this study was to investigate treatment-related behaviour and quality of life of a Polish population that reported symptoms of overactive bladder (OAB) syndrome. […] Of 6005 participants, 33.9% (n = 2041) had a possible diagnosis of OAB. Almost 40% (n = 810) were seeking treatment, and most participants received treatment (37.7%, n = 770). […] Finally, OAB had a negative effect on quality of life because 43% (n = 878) of persons with possible OAB had concerns about their quality of life related to their urinary condition. […] This study is the first Eastern European population-representative analysis of treatment-related behaviours for OAB.

• #58 Prevalence of overactive bladder symptoms and their impact on health-related quality of life of medical and dentistry students: a multicenter cross-sectional study | BMC Urology | Full Text

  https://bmcurol.biomedcentral.com/articles/10.1186/s12894-021-00909-1

  Overactive bladder (OAB) is a popular distressing health condition that has negative impact on health-related quality of life (HRQoL) of the inflicted individuals. […] Previous epidemiological studies have reported variable prevalence rates of OAB among the general public that ranged from 3 to 43%. […] Previous studies also reported that OAB was largely underestimated and undertreated among the general public. […] Previous studies have reported negative impact of OAB on the HRQoL that can be translated as negative effects on the physical, social, and psychological well-being. […] OAB can also have negative interference with the daily activities of the affected individuals. […] Additionally, OAB affects the patients relationships with spouse/partner, family, and friends. […] As a result, anxiety, depression, embarrassment, and difficulties in sleep and sexual relationships were previously reported as common among individuals with OAB.

• #59 Prevalence of overactive bladder symptoms and their impact on health-related quality of life of medical and dentistry students: a multicenter cross-sectional study | BMC Urology | Full Text

  https://bmcurol.biomedcentral.com/articles/10.1186/s12894-021-00909-1

  Overactive bladder (OAB) is a popular distressing health condition that has negative impact on health-related quality of life (HRQoL) of the inflicted individuals. […] Previous epidemiological studies have reported variable prevalence rates of OAB among the general public that ranged from 3 to 43%. […] Previous studies also reported that OAB was largely underestimated and undertreated among the general public. […] Previous studies have reported negative impact of OAB on the HRQoL that can be translated as negative effects on the physical, social, and psychological well-being. […] OAB can also have negative interference with the daily activities of the affected individuals. […] Additionally, OAB affects the patients relationships with spouse/partner, family, and friends. […] As a result, anxiety, depression, embarrassment, and difficulties in sleep and sexual relationships were previously reported as common among individuals with OAB.

• #60 Prevalence of overactive bladder symptoms and their impact on health-related quality of life of medical and dentistry students: a multicenter cross-sectional study | BMC Urology | Full Text

  https://bmcurol.biomedcentral.com/articles/10.1186/s12894-021-00909-1

  Overactive bladder (OAB) is a popular distressing health condition that has negative impact on health-related quality of life (HRQoL) of the inflicted individuals. […] Previous epidemiological studies have reported variable prevalence rates of OAB among the general public that ranged from 3 to 43%. […] Previous studies also reported that OAB was largely underestimated and undertreated among the general public. […] Previous studies have reported negative impact of OAB on the HRQoL that can be translated as negative effects on the physical, social, and psychological well-being. […] OAB can also have negative interference with the daily activities of the affected individuals. […] Additionally, OAB affects the patients relationships with spouse/partner, family, and friends. […] As a result, anxiety, depression, embarrassment, and difficulties in sleep and sexual relationships were previously reported as common among individuals with OAB.

• #61

  https://www.ics.org/2024/abstract/802

  The overall prevalences of COUB, OAB, UAB, and non-OAB/UAB were 4.3% (n = 135), 9.6% (n = 299), 5.0% (n = 155), and 81.1% (n = 2533) in men, and 1.6% (n = 50), 8.2% (n = 254), 2.4% (n = 73), and 87.8% (n = 2711) in women, respectively. The prevalence of all categories significantly increased with age. The overall prevalence of COUB in the OAB population was 31.1% (135/434) and 16.4% (50/304) in men and women, respectively, and significantly increased with age only in women. The overall prevalence of COUB in the UAB population was 46.6% (135/290) and 40.7% (50/123) in men and women, respectively, which significantly increased with age only in women. In the COUB population, the impact on QOL rated as slight or more and the proportion of physician visits was the highest among the groups. […] The prevalence of COUB increased with age. However, the prevalence of COUB with age in the OAB and UAB population differed between men and women. This suggests that gender differences should be kept in mind when considering the pathophysiology of COUB. Consistent with the results of EPIC study, COUB adversely affects participants QOL to a substantial degree, which should be associated with the higher physician visit rate than in other groups. In this large-scale cross-sectional study, the prevalence of COUB increased with age, but certain gender differences may exist. Further longitudinal studies focusing not only on OAB but also on UAB are required to elucidate the precise epidemiological aspects of COUB. This study highlighted that COUB deteriorated QOL more profoundly than OAB or UAB alone, promoting the health-care seeking behavior of the participants.

• #62 Overactive Bladder: Practice Essentials, Background, Anatomy and Physiology

  https://emedicine.medscape.com/article/459340-overview

  The prevalence of OAB increases with age, and as many as 50% of nursing-home residents have either OAB or urinary incontinence. The annual cost of managing OAB in long-term care facilities has been estimated to exceed $3 billion; this figure increases to an estimated $9 billion in the community setting. […] In total, an estimated $12.6 billion per year is spent in OAB-related costs in the United States. Some of these costs (eg, those related to physician visits, protective devices, management of UTIs, and skin infection and irritation) are obvious. Others are not. For example, decreased productivity and lost wages due to OAB is estimated to cost $841 million per year. […] Management of OAB can decrease the economic impact of OAB. Two studies have demonstrated cost savings related to the medical management of OAB. In both of these studies, savings were achieved by reducing the comorbidities of UTI and skin infection and irritation.

• #63 Overactive Bladder: Practice Essentials, Background, Anatomy and Physiology

  https://emedicine.medscape.com/article/459340-overview

  The prevalence of OAB increases with age, and as many as 50% of nursing-home residents have either OAB or urinary incontinence. The annual cost of managing OAB in long-term care facilities has been estimated to exceed $3 billion; this figure increases to an estimated $9 billion in the community setting. […] In total, an estimated $12.6 billion per year is spent in OAB-related costs in the United States. Some of these costs (eg, those related to physician visits, protective devices, management of UTIs, and skin infection and irritation) are obvious. Others are not. For example, decreased productivity and lost wages due to OAB is estimated to cost $841 million per year. […] Management of OAB can decrease the economic impact of OAB. Two studies have demonstrated cost savings related to the medical management of OAB. In both of these studies, savings were achieved by reducing the comorbidities of UTI and skin infection and irritation.

• #64

  https://journals.lww.com/co-obgyn/fulltext/2005/10000/overactive_bladder__epidemiology_and_social_impact.11.aspx?generateEpub=Article%7Cco-obgyn:2005:10000:00011%7C10.1097/01.gco.0000183529.26352.52%7C

  Overactive bladder epidemiology is a rapidly evolving field. The new terminology of lower urinary tract function, introduced in 2002, modified the definitions of all four components of overactive bladder. In the same year, the lack of specific information on overactive bladder prevalence was identified and consequently new studies were launched and recently published. […] Studies conducted in selected countries and populations suggested comparable prevalence data worldwide, although the syndrome is considered to be underreported. […] Recent epidemiological data confirm the increase in overactive bladder prevalence with age and suggest that most diet and lifestyle factors are not associated with the condition, with the exception of body mass index. […] The socioeconomic consequences of the overactive bladder syndrome were recently estimated in a large US study and a total cost of US$12.6 billion was calculated. […] Specific data on overactive bladder epidemiology are now available, providing new evidence about its relevance as a clinical issue.

• #65 Overactive Bladder: Practice Essentials, Background, Anatomy and Physiology

  https://emedicine.medscape.com/article/459340-overview

  The prevalence of OAB increases with age, and as many as 50% of nursing-home residents have either OAB or urinary incontinence. The annual cost of managing OAB in long-term care facilities has been estimated to exceed $3 billion; this figure increases to an estimated $9 billion in the community setting. […] In total, an estimated $12.6 billion per year is spent in OAB-related costs in the United States. Some of these costs (eg, those related to physician visits, protective devices, management of UTIs, and skin infection and irritation) are obvious. Others are not. For example, decreased productivity and lost wages due to OAB is estimated to cost $841 million per year. […] Management of OAB can decrease the economic impact of OAB. Two studies have demonstrated cost savings related to the medical management of OAB. In both of these studies, savings were achieved by reducing the comorbidities of UTI and skin infection and irritation.

• #66

  https://www.archivesofmedicalscience.com/Effects-of-overactive-bladder-on-treatment-related-nbehaviour-and-quality-of-life,133119,0,2.html

  The aim of this study was to investigate treatment-related behaviour and quality of life of a Polish population that reported symptoms of overactive bladder (OAB) syndrome. […] Of 6005 participants, 33.9% (n = 2041) had a possible diagnosis of OAB. Almost 40% (n = 810) were seeking treatment, and most participants received treatment (37.7%, n = 770). […] Finally, OAB had a negative effect on quality of life because 43% (n = 878) of persons with possible OAB had concerns about their quality of life related to their urinary condition. […] This study is the first Eastern European population-representative analysis of treatment-related behaviours for OAB.

• #67 Overactive Bladder Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

  https://www.researchandmarkets.com/reports/5969863/overactive-bladder-market-epidemiology?srsltid=AfmBOorTSTf6pNSrJTpS8N0EGc_2UCuXtMEVj-HR-KxjdrMsiw-_ZUaw

  The 7 major overactive bladder markets reached a value of US$ 2.5 Billion in 2023. Looking forward, the publisher expects the 7MM to reach US$ 3.3 Billion by 2034, exhibiting a growth rate (CAGR) of 3.13% during 2023-2034. […] The increasing prevalence of urinary tract infections, which cause overactivity of the detrusor urinae muscle and involuntary bladder contractions, is primarily driving the overactive bladder market. Furthermore, the rising cases of aging-related cognitive decline that make it challenging for the bladder to comprehend the signals it gets from the brain are also bolstering the market growth. […] This report provides an exhaustive analysis of the overactive bladder market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc.

• #68 Overactive Bladder: Practice Essentials, Background, Anatomy and Physiology

  https://emedicine.medscape.com/article/459340-overview

  The prevalence of OAB increases with age, and as many as 50% of nursing-home residents have either OAB or urinary incontinence. The annual cost of managing OAB in long-term care facilities has been estimated to exceed $3 billion; this figure increases to an estimated $9 billion in the community setting. […] In total, an estimated $12.6 billion per year is spent in OAB-related costs in the United States. Some of these costs (eg, those related to physician visits, protective devices, management of UTIs, and skin infection and irritation) are obvious. Others are not. For example, decreased productivity and lost wages due to OAB is estimated to cost $841 million per year. […] Management of OAB can decrease the economic impact of OAB. Two studies have demonstrated cost savings related to the medical management of OAB. In both of these studies, savings were achieved by reducing the comorbidities of UTI and skin infection and irritation.

• #69

  https://journals.lww.com/co-obgyn/fulltext/2005/10000/overactive_bladder__epidemiology_and_social_impact.11.aspx?generateEpub=Article%7Cco-obgyn:2005:10000:00011%7C10.1097/01.gco.0000183529.26352.52%7C

  Overactive bladder epidemiology is a rapidly evolving field. The new terminology of lower urinary tract function, introduced in 2002, modified the definitions of all four components of overactive bladder. In the same year, the lack of specific information on overactive bladder prevalence was identified and consequently new studies were launched and recently published. […] Studies conducted in selected countries and populations suggested comparable prevalence data worldwide, although the syndrome is considered to be underreported. […] Recent epidemiological data confirm the increase in overactive bladder prevalence with age and suggest that most diet and lifestyle factors are not associated with the condition, with the exception of body mass index. […] The socioeconomic consequences of the overactive bladder syndrome were recently estimated in a large US study and a total cost of US$12.6 billion was calculated. […] Specific data on overactive bladder epidemiology are now available, providing new evidence about its relevance as a clinical issue.

• #70 Overactive Bladder (OAB): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/14248-overactive-bladder

  Overactive bladder is most common in people 65 and older. Women may have OAB at a younger age, usually around 45. […] Overactive bladder is common. It affects up to 33 million adults in the U.S., including as many as 30% of men and 40% of women. However, that number may be higher because many people may feel embarrassed and wont get help. […] A healthcare provider can diagnose overactive bladder by reviewing your symptoms and conducting a physical examination of the organs around your pelvis and rectum. […] A healthcare provider may order tests to help diagnose overactive bladder. […] Lifestyle adjustments can help reduce your risk of developing an overactive bladder. […] Overactive bladder symptoms can cause considerable stress. Treatment can be challenging to manage, and symptoms may never completely disappear. But many people are satisfied with the treatment they receive and often experience a dramatic improvement in their quality of life. […] See a healthcare provider if you experience any symptoms of an overactive bladder.

• #71

  https://journals.lww.com/co-obgyn/fulltext/2005/10000/overactive_bladder__epidemiology_and_social_impact.11.aspx?generateEpub=Article%7Cco-obgyn:2005:10000:00011%7C10.1097/01.gco.0000183529.26352.52%7C

  Overactive bladder epidemiology is a rapidly evolving field. The new terminology of lower urinary tract function, introduced in 2002, modified the definitions of all four components of overactive bladder. In the same year, the lack of specific information on overactive bladder prevalence was identified and consequently new studies were launched and recently published. […] Studies conducted in selected countries and populations suggested comparable prevalence data worldwide, although the syndrome is considered to be underreported. […] Recent epidemiological data confirm the increase in overactive bladder prevalence with age and suggest that most diet and lifestyle factors are not associated with the condition, with the exception of body mass index. […] The socioeconomic consequences of the overactive bladder syndrome were recently estimated in a large US study and a total cost of US$12.6 billion was calculated. […] Specific data on overactive bladder epidemiology are now available, providing new evidence about its relevance as a clinical issue.

• #72 Azthena logo with the word Azthena

  https://www.news-medical.net/health/What-is-an-Overactive-Bladder.aspx

  Overactive bladder is a urological condition that involves more frequent urination than usual, such that it inhibits the individuals normal daily activities. […] It is a relatively common condition with varying severity and is estimated to affect approximately one in six adults. It is more common in the elderly population and is, therefore expected to rise in worldwide prevalence with the aging populations among developed nations. […] […] However, the actual prevalence is not clear, particularly as a recent Finnish study casted doubt on the methods used in previous research in regards to age distribution of the research population. This suggested that the prevalence is significantly lower than previously thought. […] […] Nonetheless, the condition is reported to affect between 7% and 43% of the population, with women experiencing more problems than males.

• #73 Epidemiology, prescribing patterns and resource use associated with overactive bladder in UK primary care. — Nuffield Department of Population Health

  https://www.ndph.ox.ac.uk/publications/162648

  This study aimed to estimate the incidence and prevalence of overactive bladder (OAB) symptoms in the UK and analyse the use of anticholinergic/antispasmodic medications and other healthcare resources within UK general practice. […] The overall prevalence of OAB-related symptoms was 3.87 per 1000 persons, with an incidence of 2.79 per 1000 person-years. […] In conclusion, this study suggests that OAB may be under-diagnosed in the UK and that current guidelines recommending use of anticholinergic medication, continence nurse consultations and urinary tests/investigations are inadequately followed.

• #74 The Burden of Overactive Bladder on US Public Health

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4821440/

  OAB represents a significant public health burden, as it affects one out of seven US women and a similar proportion of men. While the personal burden and individual costs related to OAB are high, OAB also accounts for considerable total annual US societal costs and can be difficult to treat effectively. Despite increased attention and research on OAB, there appear to be many unmet needs to improve the overall public health burden as it relates to OAB.

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