Nadczynność pęcherza
Objawy

Nadczynność pęcherza (OAB) to zespół objawów obejmujący parcie naglące, częstomocz (>8 mikcji/24h), nokturie (≥2 wybudzenia na mocz) oraz nietrzymanie moczu z parcia (UUI) u około 33% pacjentów. Patofizjologia opiera się na niekontrolowanych skurczach mięśnia wypieracza, nawet przy niepełnym wypełnieniu pęcherza. OAB dotyka około 16-16,5% populacji, z wyższą częstością u kobiet, szczególnie w okresie okołomenopauzalnym, oraz u osób powyżej 75. roku życia (30-40%). Objawy mogą mieć charakter przewlekły, z remisją u 37-39% przypadków w ciągu roku, ale często utrzymują się latami, wpływając negatywnie na jakość życia, funkcje społeczne i psychiczne pacjentów. Nieleczona nadczynność pęcherza może prowadzić do osłabienia mięśni dna miednicy, zmian strukturalnych pęcherza oraz zwiększonego ryzyka infekcji dróg moczowych i upadków u osób starszych.

Nadczynność pęcherza – definicja i przegląd

Nadczynność pęcherza (OAB – Overactive Bladder) to zespół objawów, charakteryzujący się nagłą, trudną do opanowania potrzebą oddania moczu (parcie naglące), zwykle połączoną z częstomoczem i nokturią, z lub bez nietrzymania moczu z parcia 12. Nadczynność pęcherza nie jest konkretną chorobą, ale zespołem objawów związanych z nieprawidłową funkcją mięśnia wypieracza pęcherza moczowego 23. W zespole tym dochodzi do niekontrolowanych skurczów mięśnia wypieracza, nawet gdy pęcherz nie jest jeszcze wypełniony 45.

Parcie naglące (urgency) jest kluczowym, osiowym objawem zespołu nadczynności pęcherza i definiowane jest jako nagła, silna potrzeba oddania moczu, której trudno zapobiec 26. To właśnie parcie naglące odgrywa istotną rolę w rozwoju pozostałych objawów OAB, takich jak częstomocz dzienny, nokturia i nietrzymanie moczu z parcia 6.

Epidemiologia nadczynności pęcherza

Nadczynność pęcherza stanowi powszechny problem zdrowotny, dotykający znaczną część populacji. Szacuje się, że zespół OAB dotyka około 16-16,5% populacji ogólnej 78. W Stanach Zjednoczonych problem ten dotyczy około 33 milionów osób, przy czym częściej występuje u kobiet niż u mężczyzn 59.

Częstość występowania OAB wzrasta wraz z wiekiem – u osób powyżej 40 roku życia szacuje się, że około 16% populacji cierpi na ten zespół, natomiast u osób powyżej 75 roku życia odsetek ten wzrasta do 30-40% 810. Nadczynność pęcherza częściej występuje u kobiet w okresie okołomenopauzalnym, co może być związane ze zmianami hormonalnymi 1112.

Badania pokazują, że około 37-39% przypadków OAB ulega remisji w ciągu roku, jednak większość pacjentów doświadcza objawów przez wiele lat 13. Należy podkreślić, że nadczynność pęcherza nie jest normalną konsekwencją starzenia się, choć jej częstość wzrasta z wiekiem 1415.

Główne objawy nadczynności pęcherza

Nadczynność pęcherza charakteryzuje się zestawem charakterystycznych objawów dotyczących funkcji dolnych dróg moczowych. Do głównych objawów OAB należą:

Parcie naglące (urgency)

Parcie naglące to nagła, intensywna potrzeba oddania moczu, której trudno zapobiec 162. Jest to osiowy objaw OAB i najczęstsza dolegliwość zgłaszana przez pacjentów 3. Pacjenci opisują to uczucie jako niepohamowaną chęć dotarcia do toalety natychmiast, gdy pojawi się uczucie parcia 17. W badaniach wykazano, że nasilenie parcia naglącego u pacjentów z OAB jest znacznie wyższe w porównaniu z innymi odczuciami (średnia ocena numeryczna 6,1±2,6 w porównaniu do odczucia bólu 2,0±2,6 czy uczucia ciśnienia 3,4±2,9) 3.

Częstomocz (frequency)

Częstomocz definiowany jest jako oddawanie moczu więcej niż 8 razy w ciągu 24 godzin 1618. U osób z nadczynnością pęcherza często występuje potrzeba oddawania moczu co dwie godziny lub częściej 19. Częstomocz był najczęściej zgłaszanym objawem OAB, dotyczącym nawet 85% pacjentów 6. Niektórzy pacjenci z OAB mogą nawet odczuwać potrzebę oddawania moczu do 30 razy dziennie 20.

Nokturia

Nokturia oznacza budzenie się w nocy więcej niż raz, aby oddać mocz 1618. Jest to szczególnie uciążliwy objaw, który znacząco wpływa na jakość snu i funkcjonowanie w ciągu dnia 7. W przypadku OAB, nokturia zazwyczaj definiowana jest jako konieczność wstawania do oddania moczu co najmniej dwa razy w ciągu nocy 2119.

Nietrzymanie moczu z parcia (urgency incontinence)

Nietrzymanie moczu z parcia (UUI) to mimowolna utrata moczu bezpośrednio po lub w trakcie nagłego parcia na mocz 2216. Objaw ten występuje u około 33% pacjentów z OAB (tzw. „mokra” nadczynność pęcherza), podczas gdy pozostałe 67% ma „suchą” nadczynność pęcherza bez epizodów nietrzymania moczu 23. UUI może obejmować niewielkie ilości moczu lub całkowitą zawartość pęcherza 24.

Nietrzymanie moczu z parcia różni się od wysiłkowego nietrzymania moczu (SUI), które występuje podczas kaszlu, kichania czy wysiłku fizycznego. Wiele kobiet może cierpieć jednocześnie na oba typy nietrzymania moczu 11.

Objawy towarzyszące i profil kliniczny

Oprócz głównych objawów, pacjenci z nadczynnością pęcherza mogą doświadczać dodatkowych dolegliwości, które uzupełniają obraz kliniczny schorzenia:

Odczucie niepełnego opróżnienia pęcherza

Wielu pacjentów z OAB zgłasza uczucie, że nie są w stanie całkowicie opróżnić pęcherza po oddaniu moczu 25. Może to prowadzić do potrzeby ponownego oddania moczu krótko po poprzedniej mikcji 26.

Zaburzenia strumienia moczu

Niektórzy pacjenci z nadczynnością pęcherza mogą doświadczać trudności z rozpoczęciem mikcji (niezdecydowanie moczowe) lub osłabienia strumienia moczu 26.

Ból lub dyskomfort

U części pacjentów z OAB występuje dyskomfort lub ból w okolicy miednicy, który może pojawiać się przed, w trakcie lub po oddaniu moczu 26. Korelacja między dyskomfortem a naglącym parciem w OAB jest umiarkowana (r=0,45) 3.

Nietrzymanie moczu podczas aktywności seksualnej

U niektórych osób z OAB może występować nietrzymanie moczu podczas stosunku płciowego (inkontynencja koitalna), co może prowadzić do zaburzeń funkcji seksualnych i obniżenia jakości życia 27.

Moczenie nocne

W ciężkich przypadkach OAB może występować moczenie nocne (enuresis nocturna), czyli mimowolne oddawanie moczu podczas snu 2711.

Przebieg i progresja nadczynności pęcherza

Nadczynność pęcherza jest schorzeniem przewlekłym, które zazwyczaj nie ustępuje samoistnie 2821. Przebieg i progresja OAB mogą różnić się znacznie między pacjentami i zależą od wielu czynników, w tym przyczyny podstawowej i skuteczności leczenia.

Początek i rozpoznanie

Objawy OAB mogą rozwijać się stopniowo lub pojawić się nagle. U osób starszych OAB związane z wiekiem zazwyczaj rozwija się powoli i stopniowo pogarsza się z upływem czasu 21. Jeśli objawy pojawiają się nagle i towarzyszy im intensywne wyciekanie moczu, OAB może być objawem innego schorzenia, takiego jak infekcja lub problem neurologiczny 21.

Większość pacjentów z OAB cierpi na objawy przez dłuższy czas, zanim zdecyduje się szukać pomocy medycznej 1329. Jest to częściowo spowodowane wstydem, zakłopotaniem lub przekonaniem, że objawy są normalną częścią procesu starzenia 24.

Zmienność i fluktuacja objawów

Objawy nadczynności pęcherza mogą się zmieniać i wahać z upływem czasu 912. U niektórych pacjentów objawy mogą się nasilać podczas okresów stresu lub po spożyciu określonych pokarmów i napojów, takich jak kofeina i alkohol 16.

Badania wskazują, że około 37-39% przypadków OAB może ulec remisji w ciągu roku, jednak większość pacjentów doświadcza objawów przez wiele lat 13. Pacjenci mogą doświadczać okresów, gdy objawy są mniej nasilone, oraz okresów zaostrzeń 30.

Progresja nieleczonego OAB

Bez odpowiedniego leczenia objawy nadczynności pęcherza mogą się pogarszać z upływem czasu 2831. Nieleczona nadczynność pęcherza może prowadzić do osłabienia mięśni pęcherza i mięśni dna miednicy, a także ścieńczenia tkanek dna miednicy, co może nasilać objawy 21.

Długotrwała nadczynność pęcherza może prowadzić do zmian strukturalnych w samym pęcherzu, w tym zmian w ścianie pęcherza spowodowanych stałym napięciem mięśni 23. Może to prowadzić do dalszego pogorszenia funkcji pęcherza i nasilenia objawów.

Czynniki wpływające na progresję

Progresja OAB może być przyspieszona przez czynniki takie jak:

  • Wiek – ryzyko i nasilenie OAB wzrasta wraz z wiekiem 32
  • Choroby współistniejące, takie jak cukrzyca, zaburzenia neurologiczne czy przerost prostaty u mężczyzn 1533
  • Otyłość, która zwiększa ciśnienie na pęcherz 33
  • Przewlekłe zaparcia, które mogą wiązać się z większą częstością występowania i nasileniem OAB 13
  • Zmiany hormonalne, szczególnie u kobiet w okresie menopauzy 1233

Wpływ nadczynności pęcherza na jakość życia

Nadczynność pęcherza może mieć znaczący wpływ na jakość życia pacjentów, wpływając na różne aspekty ich codziennego funkcjonowania 27. Wpływ ten jest niezależny od tego, czy objawy są związane z nietrzymaniem moczu 2.

Wpływ na codzienne funkcjonowanie

OAB może znacząco zakłócać codzienne aktywności, takie jak praca, ćwiczenia fizyczne i sen 1432. Pacjenci często muszą planować swoje aktywności w zależności od dostępności toalet, co może ograniczać ich możliwości podróżowania i uczestniczenia w życiu społecznym 27.

Częste wizyty w toalecie mogą zakłócać koncentrację i wydajność w pracy, a ciągłe przerywanie snu z powodu nokturii może prowadzić do zmęczenia w ciągu dnia i obniżenia ogólnej sprawności 3432.

Wpływ na zdrowie psychiczne

OAB może mieć istotny wpływ na zdrowie psychiczne pacjentów. Badania wykazały, że około 30% osób z OAB spełnia kliniczne kryteria depresji 23. Pacjenci mogą doświadczać niepokoju, stresu i obniżenia nastroju związanego z obawami o przypadkowe wyciekanie moczu lub koniecznością częstego korzystania z toalety 45.

Objawy OAB mogą również prowadzić do uczucia zakłopotania, obniżenia samooceny i poczucia utraty kontroli 275.

Wpływ na życie społeczne i relacje

OAB może prowadzić do ograniczenia aktywności społecznej i izolacji. Pacjenci mogą unikać sytuacji, w których dostęp do toalety jest ograniczony lub niepewny, co może wpływać na ich uczestnictwo w wydarzeniach społecznych i rekreacyjnych 3215.

Nadczynność pęcherza może również wpływać na relacje osobiste, w tym na intymne relacje z partnerem 3527. Problemy z funkcjami seksualnymi są częste u pacjentów z OAB i mogą obejmować dyskomfort podczas stosunku, strach przed wyciekaniem moczu oraz ogólne zmniejszenie satysfakcji seksualnej 45.

Wpływ na zdrowie fizyczne

Oprócz bezpośrednich objawów związanych z układem moczowym, nadczynność pęcherza może prowadzić do innych problemów zdrowotnych. Pacjenci z OAB są bardziej narażeni na infekcje dróg moczowych (UTI) oraz podrażnienia i infekcje skóry związane z wyciekaniem moczu 3632.

U starszych osób z OAB z nietrzymaniem moczu z parcia ryzyko upadków jest zwiększone o 26%, a ryzyko złamań o 34%, co jest związane z pośpiechem podczas dotarcia do toalety 36.

Pacjenci z OAB mogą również doświadczać odwodnienia z powodu ograniczania spożycia płynów w celu zmniejszenia częstości oddawania moczu. Przewlekłe odwodnienie może prowadzić do zwiększonego stężenia moczu, co działa drażniąco na pęcherz i może promować tworzenie się kamieni nerkowych 23.

Opcje terapeutyczne dla nadczynności pęcherza

Leczenie nadczynności pęcherza zazwyczaj wymaga kompleksowego podejścia, które może obejmować zmiany stylu życia, fizjoterapię, farmakoterapię, a w niektórych przypadkach bardziej inwazyjne interwencje 1310. Skuteczne leczenie może znacząco poprawić jakość życia pacjentów z OAB 37.

Zmiany stylu życia i terapia behawioralna

Modyfikacje behawioralne są często pierwszą linią leczenia OAB i mogą obejmować:

  • Trening pęcherza – stopniowe wydłużanie czasu między wizytami w toalecie w celu zwiększenia pojemności pęcherza 38
  • Ćwiczenia mięśni dna miednicy (ćwiczenia Kegla) – wzmacniające mięśnie kontrolujące oddawanie moczu 39
  • Modyfikacje dietetyczne – ograniczenie spożycia kofeiny, alkoholu i innych substancji drażniących pęcherz 40
  • Kontrola wagi – utrata wagi u pacjentów z nadwagą może zmniejszyć częstość epizodów nietrzymania moczu nawet o 50% 17
  • Regularne oddawanie moczu według harmonogramu, nawet bez uczucia parcia 41

Zmiany stylu życia i fizjoterapia dna miednicy mogą zmniejszyć częstość oddawania moczu o 50-80% 17.

Farmakoterapia

Leki stosowane w leczeniu OAB obejmują:

  • Leki antycholinergiczne (np. oksybutynina, solifenacyna) – działają poprzez blokowanie receptorów muskarynowych, co zmniejsza skurcze pęcherza 428
  • Agoniści receptora β3-adrenergicznego (mirabegron, vibegron) – relaksują mięśnie pęcherza, zmniejszając urgencję i częstość oddawania moczu 4233
  • Miejscowo stosowane estrogeny – mogą być korzystne u kobiet po menopauzie z atrofią pochwy 8

Leki antycholinergiczne mogą powodować działania niepożądane, takie jak suchość w ustach i oczach, zaparcia, a u osób starszych mogą przyczyniać się do zaburzeń funkcji poznawczych 4313. Mirabegron, działający poprzez inny mechanizm, może być lepszą opcją dla pacjentów, którzy nie tolerują antycholinergików 17.

Zabiegi minimalnie inwazyjne

Dla pacjentów, którzy nie reagują na leczenie behawioralne i farmakologiczne, dostępne są opcje minimalnie inwazyjne:

  • Iniekcje toksyny botulinowej (Botox) do ściany pęcherza – relaksują mięśnie pęcherza i zmniejszają częstość skurczów 1744
  • Neuromodulacja – stymulacja nerwów kontrolujących pęcherz za pomocą impulsów elektrycznych, w tym:
    • Przezskórna stymulacja nerwu piszczelowego (PTNS) 45
    • Neuromodulacja krzyżowa (SNS) 46

Leczenie chirurgiczne

W ciężkich, opornych na leczenie przypadkach OAB, można rozważyć metody chirurgiczne:

  • Augmentacja pęcherza – zabieg powiększający pojemność pęcherza 1413
  • Odprowadzenie moczu – zmiana drogi odpływu moczu 14

Leczenie chirurgiczne jest zarezerwowane dla pacjentów z ciężkimi objawami OAB, którzy nie odpowiedzieli na wszystkie inne opcje terapeutyczne 4313.

Rokowanie i perspektywy leczenia

Nadczynność pęcherza to przewlekły stan, który wymaga długoterminowego leczenia 42. Chociaż OAB rzadko zagraża życiu, może znacząco obniżać jego jakość 46.

Rokowanie dla pacjentów z OAB jest generalnie dobre. Przy odpowiednim leczeniu większość pacjentów osiąga znaczącą poprawę w zakresie kontroli objawów 5. Terapia behawioralna w połączeniu z leczeniem farmakologicznym jest często skuteczna, z poprawą w ponad 80% przypadków 47.

Należy jednak podkreślić, że OAB jest stanem przewlekłym, podobnie jak cukrzyca czy nadciśnienie, i często wymaga długotrwałego leczenia 42. U niektórych pacjentów objawy mogą nigdy nie ustąpić całkowicie, ale dostępne jest wiele metod leczenia, które mogą pomóc w zarządzaniu objawami, tak aby życie pacjenta nie było kontrolowane przez pęcherz 38.

Pacjenci, którzy nie szukają pomocy, nie mogą oczekiwać samoistnej poprawy – ich jakość życia nie poprawi się bez leczenia 37. Dlatego ważne jest, aby osoby z objawami nadczynności pęcherza konsultowały się ze specjalistami w celu ustalenia odpowiedniego planu leczenia.

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  1. 09.04.2026
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Materiały źródłowe

  • #1 The AUA/SUFU Guideline on the Diagnosis and Treatment of Idiopathic Overactive Bladder – American Urological Association
    https://www.auanet.org/guidelines-and-quality/guidelines/idiopathic-overactive-bladder
    Overactive bladder (OAB) is defined by the International Continence Society (ICS) as urinary urgency, usually accompanied by frequency and nocturia, with or without urgency urinary incontinence (UUI), in the absence of urinary tract infection (UTI) or other obvious pathology. The prevalence of OAB and its impact on quality of life (QoL) across the life span is significant. […] Patients with OAB present to several types of providers including primary care, specialty care, physical therapists, and alternative medicine providers. The purpose of this OAB guideline is to provide evidence-based guidance to all types of clinicians and patients regarding the evaluation, management, and treatment of idiopathic OAB. The guideline informs the reader on valid diagnostic processes and provides an approach to maximizing symptom control and patient QoL through shared decision-making, while minimizing adverse events and burden of disease.
  • #2 Overactive Bladder: Practice Essentials, Background, Anatomy and Physiology
    https://emedicine.medscape.com/article/459340-overview
    Overactive bladder (OAB) is a syndrome characterized by a sudden and compelling need to urinate. OAB affects physical functioning, social functioning, vitality, and emotional roles. […] Clinical manifestations of overactive bladder OAB include the following: Urinary urgency (hallmark symptom), urgency urinary incontinence (may or may not be present), urinary frequency and nocturia (usually present). […] Urgency, the hallmark of OAB, is defined as the sudden compelling desire to urinate, a sensation that is difficult to defer. Urgency urinary incontinence (UUI) is urinary leakage associated with urgency. UUI is one of the most common types of urinary incontinence. […] OAB appears to be multifactorial in both etiology and pathophysiology. Symptoms of OAB are suggestive of underlying detrusor overactivity. Overactivity of the detrusor muscle—neurogenic, myogenic, or idiopathic in origin—may result in urinary urgency and urgency incontinence.
  • #2 Overactive Bladder: Practice Essentials, Background, Anatomy and Physiology
    https://emedicine.medscape.com/article/459340-overview
    The prevalence of OAB increases with age. However, OAB should not be considered a normal part of aging. […] OAB significantly impairs QoL, increases depression scores, and reduces quality of sleep. OAB that involves urgency incontinence is associated with the most severe impairment. […] The impact of OAB on QoL is independent of whether the symptoms are associated with urinary incontinence. Studies with the Short Form-36 (SF-36), a generic QoL questionnaire, demonstrated that OAB affects physical functioning, social functioning, vitality, and emotional roles. […] The annual cost of managing OAB in long-term care facilities has been estimated to exceed $3 billion; this figure increases to an estimated $9 billion in the community setting. […] In total, an estimated $12.6 billion per year is spent in OAB-related costs in the United States.
  • #3 Assessment of bladder pressure and discomfort symptoms: How do overactive bladder differ from interstitial cystitis/bladder pain syndrome patients? | BMC Urology | Full Text
    https://bmcurol.biomedcentral.com/articles/10.1186/s12894-022-01164-8
    Among OAB patients (n=51), their mean numeric ratings of pain, pressure, and discomfort (2.02.6, 3.42.9, 3.42.9) were significantly lower than urgency (6.12.6, p0.001). […] The most bothersome symptom of OAB was urinary urgency and daytime frequency. […] Among OAB patients, the correlations between pain and urgency (the cardinal symptom of OAB), and between pressure and urgency were weak (0.21 and 0.26). The correlation between discomfort and urgency was moderate in OAB (r=0.45). […] The most bothersome symptom of OAB patients is urinary urgency and frequency.
  • #4 Overactive bladder – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/overactive-bladder/symptoms-causes/syc-20355715
    Overactive bladder, also called OAB, causes sudden urges to urinate that may be hard to control. There might be a need to pass urine many times during the day and night. There also might be loss of urine that isn’t intended, called urgency incontinence. […] If you have an overactive bladder, you may: Feel a sudden urge to urinate that’s hard to control. Lose urine without meaning to after an urgent need to urinate, called urgency incontinence. Urinate often. This can mean eight or more times in 24 hours. Wake up more than twice a night to urinate, called nocturia. […] Overactive bladder happens when the muscles of the bladder start to tighten on their own even when the amount of urine in the bladder is low. These are called involuntary contractions. They cause an urgent need to urinate.
  • #4 Overactive bladder – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/overactive-bladder/symptoms-causes/syc-20355715
    Aging increases the risk of overactive bladder. So does being female. Conditions such as enlarged prostate and diabetes also can increase the risk. […] Any type of incontinence can affect quality of life. If your overactive bladder symptoms disrupt your life, you might also have: Anxiety. Emotional distress or depression. Sexual problems. Sleep disturbances and interrupted sleep cycles.
  • #5 Overactive Bladder (OAB) Causes, Symptoms, Treatment
    https://www.medicinenet.com/overactive_bladder/article.htm
    Overactive Bladder Urinary urgency and frequent urination are symptoms of overactive bladder. […] Overactive bladder (OAB) is a syndrome that is characterized by urgency to urinate, frequent urination, and urination overnight. […] In some people, the muscles in the bladder wall are more sensitive and the reflexes to empty the bladder occur even when the bladder is not full enough to empty. This causes the symptoms of OAB: urgency, the feeling that one must urinate almost immediately; frequency of urination, or polyuria; overnight, interferes with sleep, or nocturia. […] Urgency urinary incontinence is the syndrome where OAB is associated with urinary leakage or incontinence. There is an intense urge to urinate followed by an involuntary loss of urine. […] OAB affects both men and women and becomes more common as people age.
  • #5 Overactive Bladder (OAB) Causes, Symptoms, Treatment
    https://www.medicinenet.com/overactive_bladder/article.htm
    The symptoms of an overactive bladder include urgency, frequency, and urination overnight. […] OAB may cause significant social and psychological issues, including always needing to know where bathroom facilities are located, and the potential and worry of urinary incontinence in public. OAB can cause depression and anxiety, affect sexual activity, impair work performance, and lead to social isolation. […] OAB can affect quality of life, work and social function, and sleep patterns leading to anxiety, depression, and potential social isolation. […] The prognosis for overactive bladder is generally good. Through a combined approach of behavioral modifications and medications, most patients are able to control their symptoms and achieve an improved quality of life. […] Unfortunately, for those who are elderly and frail, the side effects of medications may not be tolerated and their prognosis is less positive.
  • #6 Managing the symptoms of overactive bladder – The Pharmaceutical Journal
    https://pharmaceutical-journal.com/article/ld/managing-the-symptoms-of-overactive-bladder
    Overactive bladder (OAB) is defined as the combined presence of symptoms of urinary urgency, usually accompanied by frequency and nocturia (the need to wake in the night to urinate), with or without urgency incontinence, in the absence of urinary tract infection (UTI) or other obvious pathology. […] Frequency was the most commonly reported symptom (85%), while 54% complained of urgency and 36% of urgency incontinence. […] Urgency is now generally regarded as being the driving symptom of OAB and is known to play an important role in the development of daytime frequency, nocturia and urgency incontinence. […] The symptoms of OAB in people with underlying detrusor overactivity (UDO) are owing to involuntary contractions of the bladder muscle during the filling phase of the micturition cycle.
  • #7 Overactive Bladder Syndrome: Evaluation and Management
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5903463/
    Overactive bladder (OAB) syndrome is a chronic medical condition which has a major influence on the quality of life in a significant amount of the population. OAB affects performance of daily activities and has an estimated prevalence of 16.5%. […] Nocturia is reported as the most bothersome symptom in the elderly population. […] Urgency is the key symptom in diagnosing OAB and it is closely associated with frequent daytime desire to urinate, nocturia, and incontinence. Nocturia is reported as the most bothersome symptom. […] Although OAB can affect children and young adults, this condition is most common in patients over 40 years old. […] Since the frequency and consequences of OAB is more significant in elderly patients, this group of the population has to be more carefully evaluated for relevant complains.
  • #7 Overactive Bladder Syndrome: Evaluation and Management
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5903463/
    OAB syndrome pathological conditions affect the bladder’s sensory pathway and contribute to the urge to urinate at a low bladder volume. […] A bladder diary which describes the day-to-day bladder habits and patterns related to urination is the simplest and most important initial assessment tool. […] OAB sufferers may have urgency, frequency (more than 8 voids per 24 hours), or nocturia (one or more voids after falling asleep and a return to sleep after voiding), with or without urge incontinence. […] The aim of non-pharmacological treatment is to educate patients about OAB and help them to develop strategies to manage urge and urge incontinence. […] Antimuscarinic agents remain the most effective and simple option to treat the complex symptoms of OAB, and their pharmacological profiles have been well studied and recently confirmed by a large scale meta-analysis. […] There is a significant influence of OAB on health-related quality of life.
  • #8 Primary care management of overactive bladder symptoms: evaluation and treatment
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5565819/
    Symptoms suggestive of overactive bladder (OAB) have a relatively high prevalence, with an estimated 16% of patients aged 40 years living with the condition. It affects both sexes and its prevalence increases with age. The International Continence Society defines OAB as urinary urgency, usually associated with frequency and nocturia, with or without urge incontinence, in the absence of urinary tract infection or other obvious pathology. It continues to have a significant impact on quality of life and has been associated with increased falls, fracture risk, and skin breakdown. […] A diagnosis of OAB is initially based on a good history. Patients should be asked about the onset and duration of symptoms, which symptoms are the most bothersome, and any related concerns that they may have. Storage lower urinary tract symptoms (LUTS) predominate and should be noted: urgency, frequency, nocturia, or urinary incontinence (UI). If UI occurs it is important to establish what type, as both stress UI and urgency UI can coexist.
  • #8 Primary care management of overactive bladder symptoms: evaluation and treatment
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5565819/
    Conservative therapy should be first line as it has a low risk profile. It involves shared decision making as patient involvement and cooperation are integral to management. This will include behavioural changes and lifestyle adjustments such as altering fluid intake, bladder retraining, weight loss, smoking cessation, and avoiding exacerbants (for example, the caffeine found in tea, coffee, cola and energy drinks). […] Antimuscarinics are used for the treatment of OAB symptoms but should be prescribed cautiously in older patients due to the side effect profile of these drugs. Various medications that are used in older patients have an anticholinergic burden that can be associated with clinically significant adverse events including cognitive impairment. […] Mirabegron is a selective beta-3 agonist and is often recommended if antimuscarinics are contraindicated, or as a second- or third-line treatment following the use of antimuscarinics.
  • #8 Primary care management of overactive bladder symptoms: evaluation and treatment
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5565819/
    Topical oestrogen can be beneficial in the context of vaginal atrophy and may help improve symptoms in post-menopausal women. […] As OAB is mainly a clinical diagnosis with very few specialised tests, it is expected that GPs will be able to start treatment in uncomplicated cases. […] Treating patients with OAB can be rewarding, and a good clinical history together with clinical examination will allow for a systematic approach to management. It is crucial that the patient understands the role they play in the management of their symptoms.
  • #9 Overactive Bladder: Symptoms, Causes, and Treatments
    https://www.healthline.com/health/overactive-bladder
    An overactive bladder (OAB) causes a sudden urge to urinate. It can also trigger involuntary loss of urine, known as incontinence. Overactive bladder affects about 33 million Americans. Women are more often affected than men. […] Symptoms include: an urgent and uncontrollable need to urinate, frequent involuntary loss of urine, frequent urination (more than eight times in a 24-hour period), waking up more than once a night to use the bathroom. […] Symptoms of overactive bladder can change. They may be different from person to person, too, which can make identifying the issue difficult without a doctor’s help. Knowing the symptoms of overactive bladder can help you find better treatments faster. […] Symptoms of overactive bladder in men include: an urgent need to urinate, urinating up to eight times per day, experiencing urine leakage, feeling an urge to urinate that’s so strong it can’t be controlled.
  • #10 Diagnosis and Management of Overactive Bladder | AAFP
    https://www.aafp.org/pubs/afp/issues/2004/1001/p1386.html
    Patients with overactive bladder typically have a variety of symptoms that may include urinary urgency and frequency, nocturia, and urge incontinence. […] The condition is frequently encountered and affects an estimated 30 to 40 percent of persons 75 years of age or older. […] Patients with symptoms of overactive bladder often withdraw from their usual social activities, are more likely to be depressed, and may suffer from sleep disruption because of nocturia. […] Overactive bladder has a multifactorial etiology in most persons. […] The multifactorial causes of bladder dysfunction typically necessitate a multimodal approach to treatment that includes behavioral and pharmacologic interventions. […] Anticholinergic medications are the mainstay of drug therapy for overactive bladder.
  • #10 Diagnosis and Management of Overactive Bladder | AAFP
    https://www.aafp.org/pubs/afp/issues/2004/1001/p1386.html
    The chief problems occurring with these medications are side effects and incomplete efficacy. […] Older men with prostatic hypertrophy may benefit from alpha-blocker medications and should be watched for urinary retention if anticholinergic drugs are employed. […] The review discusses a number of investigational medications, which may have promise for treatment of overactive bladder.
  • #11 Overactive Bladder (OAB) Symptoms & Causes – Top Urologists
    https://auspecialists.com/overactive-bladder-symptoms-causes/
    Overactive Bladder (OAB) symptoms of urgency, frequency, and leakage are very common for both women and men. […] The chances of experiencing OAB increase when a woman goes through menopause. […] OAB symptoms are not normal at any age. […] You may be experiencing the following primary symptoms of OAB. […] Frequent, sudden, strong urges to urinate with little or no chance to postpone urination. […] Having to urinate more than 8 times over 24 hours. […] Having to urinate 2 or more times at night. […] An involuntary loss of or leaking of urine following a sudden, strong desire to urinate. […] Sometimes the cause of overactive bladder is unknown. […] Some known causes include hormonal changes in women during menopause, various medications (i.e. water pills), excess consumption of caffeine or alcohol, or certain foods (i.e. artificial sweeteners, spicy foods), abnormalities in the bladder, bladder outlet obstruction (i.e. enlarged prostate, urethral scar formation), neurological disorders (i.e. stroke, MS) or Diabetes.
  • #11 Overactive Bladder (OAB) Symptoms & Causes – Top Urologists
    https://auspecialists.com/overactive-bladder-symptoms-causes/
    Urge incontinence is a component of overactive bladder. […] Symptoms include the sudden, uncontrollable need to urinate which can lead to urinary accidents. […] The urge to urinate can also be especially strong at night (nocturia) and can lead to accidental leakage while sleeping (enuresis). […] Many people who have the symptoms of overactive bladder also suffer from stress incontinence. […] It is important to remember that stress incontinence is NOT the same as overactive bladder. They have different symptoms, causes, and therefore, different treatments.
  • #12 Overactive Bladder: Symptoms, Causes, and Treatment | MedPark Hospital
    https://www.medparkhospital.com/en-US/disease-and-treatment/overactive-bladder
    Overactive bladder occurs when the bladder muscles contract involuntarily, leading to a sudden and urgent need to urinate, which can result in urinary incontinence. […] Overactive bladder can be due to aging, neurological disorders, diabetes, certain medications, caffeine, alcohol, and other factors. In the United States, approximately 10-30% of men and 10-40% of women are affected by this condition. […] Frequent urination […] Urinary urgency is a sudden and intense urge that cannot be put off […] Urge incontinence […] Nocturia, urinate at least two times a night […] Strong urge to urinate but passing only a small amount of urine at a time. […] An overactive bladder may come and go. Symptoms may wax and wane. […] Menopause leads to a decrease in estrogen levels, weakening the pelvic floor muscles and triggering overactive bladder symptoms. […] Overactive bladder is treatable by lifestyle modification, medications, and nerve stimulation. […] Bladder training takes around 6-8 weeks. You must be patient to achieve an improvement.
  • #13 The AUA/SUFU Guideline on the Diagnosis and Treatment of Idiopathic Overactive Bladder – American Urological Association
    https://www.auanet.org/guidelines-and-quality/guidelines/idiopathic-overactive-bladder
    OAB symptom prevalence and severity tend to increase with age. A proportion of OAB cases (37-39%) remit during a given year, but the majority of patients have symptoms for years. […] The hallmark symptom of OAB is bothersome urgency which may be accompanied by UUI. Often, symptoms of urinary frequency (both daytime and nighttime) are also reported and support a diagnosis of OAB. It is common for patients to have suffered with their symptoms for an extended time before seeking medical advice. […] A diagnosis of nocturnal polyuria (i.e., the production of greater than 20% to 33% of total 24-hour urine output during the period of sleep) is largely age-dependent: 20% for younger individuals and 33% for elderly individuals. […] Chronic constipation has been associated with greater prevalence and severity of OAB.
  • #13 The AUA/SUFU Guideline on the Diagnosis and Treatment of Idiopathic Overactive Bladder – American Urological Association
    https://www.auanet.org/guidelines-and-quality/guidelines/idiopathic-overactive-bladder
    The negative impact of OAB symptoms on psychological well-being and QoL also has been well-documented. Lack of bladder control can profoundly affect an individual’s ability to travel away from home, perform occupational duties, and engage in social activities. […] Management of OAB symptoms with behavioral approaches, pelvic floor muscle training (PFMT), medications, neuromodulation, and other therapies, balanced against adverse events, costs, and patient compliance, has been reported to improve patient QoL. […] In patients with OAB whose symptoms do not adequately respond to monotherapy, clinicians may combine one or more of the following: behavioral therapy, non-invasive therapy, pharmacotherapy, and/or minimally invasive therapies. […] Clinicians should offer antimuscarinic medications or beta-3 agonists to patients with OAB to improve urinary urgency, frequency, and/or urgency urinary incontinence.
  • #13 The AUA/SUFU Guideline on the Diagnosis and Treatment of Idiopathic Overactive Bladder – American Urological Association
    https://www.auanet.org/guidelines-and-quality/guidelines/idiopathic-overactive-bladder
    Clinicians should counsel patients with OAB on the side effects of all oral medication options; treatment should be chosen based on side effect profiles and in the context of shared decision-making. […] There is mounting evidence to suggest an association between antimuscarinic medications and the development of incident dementia. […] The clinician may offer bladder augmentation cystoplasty or urinary diversion in severely impacted patients with OAB who have not responded to all other therapeutic options. […] Clinicians should only recommend chronic indwelling urethral or suprapubic catheters to patients with OAB when OAB therapies are contraindicated, ineffective, or no longer desired by the patient and always in the context of shared decision-making due to risk of harm.
  • #14 Overactive Bladder | University of Michigan Health
    https://www.uofmhealth.org/conditions-treatments/adult-urology/overactive-bladder
    Overactive bladder (OAB) is the name for a group of urinary symptoms. The most common symptom is a sudden, uncontrolled need or urge to urinate. Some people will leak urine when they feel this urge. Another symptom is the need to pass urine many times during the day and night. […] OAB can get in the way of your work, social life, exercise and sleep. Without treatment, OAB symptoms can make it hard to get through the day without many trips to the bathroom. You may not want to go out with friends or go far from home because you’re afraid of being far from a bathroom. This makes many people feel lonely and isolated. […] OAB is not a normal part of getting older. OAB is not just part of being a woman. OAB is not just an issue with the prostate. OAB is not caused by something you did. […] The major symptom of OAB is a sudden, strong urge to urinate that you can’t ignore. This „gotta go” feeling makes you fear you will leak if you don’t get to a bathroom right away.
  • #14 Overactive Bladder | University of Michigan Health
    https://www.uofmhealth.org/conditions-treatments/adult-urology/overactive-bladder
    If lifestyle changes and medicine arent working, injections may be offered. […] Another treatment for people who need extra help is nerve stimulation, also called neuromodulation therapy. […] Surgery is only used in very rare and serious cases. There are two types of surgery available. Augmentation cystoplasty enlarges the bladder. Urinary diversion re-routs the flow of urine.
  • #15 What Is Overactive Bladder? Symptoms, Causes, Diagnosis, Treatment, and Prevention
    https://www.everydayhealth.com/overactive-bladder/
    Overactive bladder happens when your bladder muscles contract (squeeze) too readily, giving you a stronger or more frequent urge to urinate. […] Several different health issues can contribute to overactive bladder, including the following: Neurologic disorders or damage (including stroke and multiple sclerosis), Diabetes, Hormonal changes around menopause in women, Weak or spastic pelvic muscles, Urinary tract infection (UTI), Drug side effects, Excess caffeine or alcohol intake, Bladder abnormalities (such as tumors or bladder stones), Enlarged prostate in men, Constipation, Declining cognitive function associated with age. […] Youre more likely to experience overactive bladder as you age, but this doesnt mean its an inevitable or normal part of aging. […] Overactive bladder is a set of symptoms, not a disease in its own right. How long your OAB lasts, and whether it gets better or worse, will depend on the underlying causes.
  • #15 What Is Overactive Bladder? Symptoms, Causes, Diagnosis, Treatment, and Prevention
    https://www.everydayhealth.com/overactive-bladder/
    If drugs dont deliver the relief you need, your doctor may give you onabotulinumtoxina (Botox) to help relax your bladder muscle. […] Overactive bladder can have a significant negative impact on your quality of life. It can interfere with your work, sleep, exercise, social life, and sex life. […] Many people with OAB are nervous about having access to a restroom outside their home and may shy away from certain social activities or even everyday errands. […] If you need to get up several times during the night to urinate, it may be difficult to get restful sleep. This can leave you tired during the day and contribute to mood disorders, like depression and anxiety. […] Its estimated that as many as 30 percent of men and 40 percent of women will develop symptoms of overactive bladder at some point in their life.
  • #16 What is overactive bladder syndrome?
    https://patient.info/womens-health/lower-urinary-tract-symptoms-in-women-luts/overactive-bladder-syndrome-oab
    Overactive bladder syndrome is very common. Symptoms of overactive bladder include an urgent feeling that you need to go to the toilet, needing to pass urine frequently and sometimes leaking urine before you can get to the toilet. […] The symptoms of OAB syndrome include: […] Urgency: This means that you have a sudden urgent desire to pass urine. You are not able to put off going to the toilet. […] Frequency: This means going to the toilet more often than normal – usually more than eight times a day. In many cases it is a lot more than eight times a day. […] Nocturia: This means waking to go to the toilet more than once at night. […] Urge incontinence: This occurs in some people with OAB. It is a leaking of urine, sometimes quite large amounts, before you can get to the toilet when you have a feeling of urgency.
  • #16 What is overactive bladder syndrome?
    https://patient.info/womens-health/lower-urinary-tract-symptoms-in-women-luts/overactive-bladder-syndrome-oab
    The cause of OAB syndrome is not fully understood. The bladder muscle (detrusor) seems to become overactive and squeeze (contract) when you don’t want it to. […] In most cases, the reason why an OAB develops is not known and the condition is then referred to as 'overactive bladder syndrome’. Symptoms may become worse at times of stress. Symptoms may also be made worse by caffeine in tea, coffee, cola, etc and by alcohol. […] Bladder training is the main treatment. This can work well in up to half of cases. […] Medication may be advised instead of, or in addition to, bladder training. […] Medicines called antimuscarinics (also called anticholinergics) may also be used for treating overactive bladder. […] Medication improves bladder control problems in some cases but not in all. The amount of improvement varies from person to person. […] If the above treatments are not successful and intermittent self-catheterisation is also not appropriate, surgery may be suggested to treat OAB syndrome.
  • #17 Overactive Bladder Causes & Treatments | CU Urogynecology | Denver
    https://urogyn.coloradowomenshealth.com/conditions/bladder/overactive-bladder.html
    Overactive bladder (OAB) is a group of urinary symptoms that produces the feeling that one has to go to the bathroom urgently (gotta go) and often. […] Women also may have accidental leakage of urine with urgency and leak urine because they cant get to the bathroom in time (urge incontinence). Some women also wake up many times in the middle of the night to urinate (pee). […] OAB makes people feel like they gotta go suddenly and much too often. […] About 40% of women and 30% of men have OAB symptoms, reports the Urology Care Foundation. Women over age 45 are more likely to have OAB, especially if they are entering menopause. […] OAB occurs when the brain and bladder have mixed up nerve signals. The brain may tell the bladder to empty when it isnt really full, producing that feeling of gotta go when really there isnt much urine there.
  • #17 Overactive Bladder Causes & Treatments | CU Urogynecology | Denver
    https://urogyn.coloradowomenshealth.com/conditions/bladder/overactive-bladder.html
    OAB and urge incontinence are common in neurologic conditions such as stroke, multiple sclerosis, Parkinsons disease, or as a result of back or pelvic surgery, herniated discs or radiation treatments. […] Women who experience signs of overactive bladder and have any of the risk factors above should seek medical care. […] The simplest treatment is to make changes in lifestyle that can reduce overactive bladder symptoms. […] Weight loss can also benefit overweight women with OAB. Studies have shown that weight loss can reduce the frequency of leaking episodes (incontinence) by almost 50%! […] Lifestyle changes and pelvic floor therapy can reduce urination frequency by 50% 80%. […] Anticholinergic drugs have been widely prescribed for OAB for many years and are a good choice for some patients.
  • #17 Overactive Bladder Causes & Treatments | CU Urogynecology | Denver
    https://urogyn.coloradowomenshealth.com/conditions/bladder/overactive-bladder.html
    A newer medication, called Myrbetriq (mirabegron) works differently (its a beta-3 agonist), and is a good option for many patients who are not good candidates for anticholinergics or wish to avoid the above risks. […] Botox injections relax the bladder muscles and prevent them from squeezing too much, which can result in reduced urges to urinate and less leaking episodes. […] Nerve stimulation, also called neuromodulation therapy, sends electrical stimulation to the bladder through nerves. This can help correct faulty signaling between the brain and bladder.
  • #18 Overactive Bladder: Symptoms, Treatment, Medications & Causes
    https://www.emedicinehealth.com/overactive_bladder/article_em.htm
    Overactive bladder (OAB) is a bladder disorder that results in an abnormal urge to urinate, urinary frequency, and nocturia (voiding at night). Some patients may also experience urinary incontinence (involuntary loss of bladder control). […] The hallmark of OAB is urinary urgency, a sudden urge to urinate that may be difficult to control. Actual loss of urine (incontinence) is not a defining symptom of an overactive bladder, but it can happen as a result of urgency. Urinary incontinence tends to be more common in women with OAB compared to men. […] The other symptoms of overactive bladder are urinary frequency (urinating more than eight times in 24 hours without any other reason, such as taking water pills) and nighttime urination or nocturia (waking up at least twice in the middle of the night to void). […] Generally, the prognosis for overactive bladder is favorable. A majority of individuals with this condition are successfully treated via behavioral and medical therapies.
  • #19 Overactive Bladder – Symptoms, Causes, & Treatments
    https://www.advancedurologyinstitute.com/condition/overactive-bladder-oab/
    Overactive bladder, also called OAB, causes a frequent and sudden urge to urinate that may be difficult to control. You may feel like you need to pass urine many times during the day and night and may also experience leakage. […] Common symptoms: A sudden urge to urinate that is difficult to control and results in running to the bathroom. Unintentional loss of urine immediately after an urgent need to urinate. Urinating sooner than every 2 hours. Waking up more than two times in the night to urinate (nocturia). […] Medications: Anticholinergics or Beta-agonists can relax the muscles of the bladder making urination less frequent and urgent. These medications may also improve the number of times you wake up at night to urinate. […] Botox: A minimally invasive procedure where Botox is injected into the muscles of the bladder to improve relaxation and decrease urgency, frequency, and waking up at night to urinate.
  • #20 Overactive Bladder | Denver Female Urology Associates
    https://www.denverurology.com/urology/oab/
    Overactive bladder (OAB) is a bladder storage problem that causes women to experience the urgent and frequent need to urinate, more than eight times each day. […] OAB affects both men and women with an estimated 40 percent of women in the U.S. experiencing OAB symptoms. […] Patients with OAB may need to use the bathroom up to 30 times a day. […] Women with OAB often experience urinary incontinence when they are unable to reach the toilet before involuntary urination begins. […] The most common symptoms of overactive bladder are urinary frequency and the sudden urge to urinate. If a woman is urinating more than eight times a day, this might be a symptom of OAB. Waking up in the middle of the night to urinate often indicates OAB, as well. […] Nerve stimulation has been shown to help people with urinary retention and overactive bladder symptoms including urinary urge incontinence, urgency and frequency.
  • #21 Overactive Bladder (OAB): Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/14248-overactive-bladder
    Urge incontinence is a sudden, uncontrollable need to pee, and you may leak pee. […] Nocturia is the need to get up to pee at least two times each night. […] Conditions or injuries that affect your detrusor muscle cause overactive bladder. […] If treatments don’t work for you, or if you’re waiting for them to take effect, incontinence products such as disposable pads or adult diapers can help you feel in control and improve your quality of life. […] Age-related OAB may develop gradually and slowly worsen over time. If your symptoms develop suddenly and you have heavy leakage, your OAB may be a symptom of another condition, such as an infection or a neurological issue.
  • #21 Overactive Bladder (OAB): Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/14248-overactive-bladder
    Overactive bladder (OAB) is a combination of symptoms that may cause you to urinate (pee) more frequently, have uncontrollable urges to pee, experience incontinence and have to pee at night. […] Overactive bladder symptoms can cause stress and affect your quality of life. […] No, overactive bladder doesn’t go away on its own. If you don’t treat OAB, your symptoms can get worse, the muscles in your bladder that help control when you pee can become weak and your pelvic floor tissues can get thinner. […] Overactive bladder represents a collection of symptoms. These symptoms include: Urinary urgency. Urinary urgency is a sudden, uncontrollable need to pee. Once you feel the need to pee, you have a short amount of time to get to a bathroom. […] A frequent need to pee means you have to go to the bathroom more often than usual.
  • #22
    https://www.nhs.uk/conditions/urinary-incontinence/symptoms/
    Urge incontinence, or urgency incontinence, is when you feel a sudden and very intense need to pass urine and you’re unable to delay going to the toilet. There are often only a few seconds between the need to urinate and the release of urine. […] This type of incontinence often occurs as part of a group of symptoms called overactive bladder syndrome, which is when the bladder muscle is more active than usual. […] As well as sometimes causing urge incontinence, overactive bladder syndrome can mean you need to pass urine very frequently, including several times during the night.
  • #23 Overactive Bladder: Signs, Symptoms, and Complications
    https://www.verywellhealth.com/overactive-bladder-symptoms-5114619
    People with OAB will typically compensate for urinary urgency by going to the bathroom frequently. This can cause extreme awkwardness in social or work situations, as well as emotional aggravation when at home or in public. […] Urinary frequency, the need to urinate more frequently than normal, is typically described as having to urinate more than seven times within the course of 24 hours. […] People with OAB often experience a form of urinary incontinence known as urge incontinence. Also referred to as wet OAB, urge incontinence is triggered by sudden spasms of the bladder wall that cause the spontaneous loss of urine. […] Not everyone with OAB will experience urinary incontinence. Most research suggests that around 67% of adults will experience dry OAB while 33% will experience wet OAB.
  • #23 Overactive Bladder: Signs, Symptoms, and Complications
    https://www.verywellhealth.com/overactive-bladder-symptoms-5114619
    In the past, OAB was not thought to be a progressive disease but rather one that was variable and could fluctuate over time. There is increasing evidence that this is not the case in all people and that, if left untreated, OAB can cause a number of short-term and long-term complications. […] Polyuria is almost invariably linked to an increased risk of dehydration. In people with OAB, in whom polyuria may be chronic, the loss of body fluids increases the concentration of urine, which acts as an irritant in the bladder. […] Chronic dehydration can also promote the formation of urinary crystals that develop into renal calculi (kidney stones) over time. […] The persistent stress placed on the bladder from years of muscular contractions can induce structural changes to the bladder itself.
  • #23 Overactive Bladder: Signs, Symptoms, and Complications
    https://www.verywellhealth.com/overactive-bladder-symptoms-5114619
    Beyond the physical toll that OAB can inflict on the body, it can also cause serious emotional harm to people unable to cope with their urinary symptoms. […] A 2016 study published in BMC Urology reported that around 30% of people with OAB meet the clinical definition of depression. […] If treated appropriately, symptoms of OAB may be greatly reduced and in some cases disappear altogether.
  • #24 What Is Overactive Bladder (OAB)? – National Association For Continence
    https://nafc.org/overactive-bladder/
    Frequent urination, usually more than eight times in 24 hours. […] Waking up more than once in the night to urinate (this is called nocturia). […] With Overactive Bladder, a person may be suddenly aware of the urgency sensation but is unable to get to the toilet before losing control of his or her urine. Urine loss can be in large amounts that soak underwear and even outer clothing. […] Research indicates that most people believe the symptoms of an overactive bladder (urinary urgency, frequency, and/or urgency incontinence) are an inevitable and normal part of growing older, rather than a treatable medical problem. […] In fact, fewer than half of individuals with incontinence actually consult a healthcare provider about their problem. This is unfortunate, since there are many treatments available to combat symptoms of OAB.
  • #25 Overactive bladder: Symptoms, treatments, and lifestyle remedies
    https://www.medicalnewstoday.com/articles/316670
    The bladder collects urine from the kidneys and expels it when it is full. If a bladder is overactive, a person cannot control when they choose to urinate, and the number of times they urinate during the day. […] The condition occurs when a persons bladder squeezes frequently or without warning. As a result, they may have to use the bathroom more frequently or urine may leak out. […] An overactive bladder will cause a group of symptoms, all of which can affect a persons quality of life. […] An overactive bladder may cause a number of different symptoms including urinating more than eight times a day and leaking urine when the need to urinate arises. […] A person with an overactive bladder may often feel like they cant completely empty their bladder. They may use the restroom and then feel like they need to go again a very short time after.
  • #26 Overactive Bladder Symptoms: How to Identify Them – Urology Center of IowaAccessibility ToolsIncrease TextDecrease TextGrayscaleHigh ContrastNegative ContrastLight BackgroundLinks UnderlineReadable FontReset
    https://www.iowauro.com/blog/overactive-bladder-symptoms-how-to-identify-them
    Urge Incontinence: In some cases, the sudden and intense urge to urinate can lead to an unintentional leakage of urine (urinary incontinence). For those with an overactive bladder, it’s common to have difficulty reaching the bathroom in time and have the need to wear an absorbent pad or brief to prevent accidents. […] Urinary Hesitancy and Weak Urine Stream: Difficulty initiating a urine stream or a weak one can also be common with overactive bladder. […] Urinary Retention: Overactive bladder symptoms can cause you to be unable to fully empty your bladder by urinating, leading to feeling like you have to urinate almost immediately after you’ve finished in the bathroom. […] Pain or Discomfort: Some people with overactive bladder experience pelvic pain and discomfort both with urination, before urination, or after urination.
  • #27 Overactive Bladder
    https://bladderhealthuk.org/page/index/306
    Overactive Bladder is a problem that affects the bladders ability to hold urine. When a healthy bladder is filled with urine, it stretches and expands to accommodate the increased volume. Specialized nerves in the bladder lining can then sense when the bladder is full and signal to the brain that it is time to empty. […] For people with OAB, however, there is thought to be abnormal communication between the brain and the bladder such that the bladder muscle (the detrusor muscle) contracts too often or spontaneously and involuntarily. You may experience a strong, sudden urge to pee even when the bladder volume is low. This can lead to not only frequent passing of urine, but also involuntary leakage (better known as incontinence). […] Symptoms of OAB can differ from person to person and they may change over time. Patients may experience some or all of the following symptoms: Frequency – The need to pass urine more than 8 times during the day. Nocturia – The need to get out of bed at night to pass urine more than once. Nocturnal Enuresis – Urinating during sleep. Urgency – The sudden need to pass urine before reaching a toilet. Coital incontinence – Leaking urine during sex.
  • #27 Overactive Bladder
    https://bladderhealthuk.org/page/index/306
    Incidents of overactive bladder can increase with age. Those with overactive bladders do not always seek medical help or advice due to embarrassment or the belief that there is no help available because it is a natural consequence of aging or for women it is a consequence of childbirth. […] All aspects of quality of life may be affected when suffering from an overactive bladder. Travelling may be difficult due to concerns over possible urine leakage or locating the nearest toilet. […] Individuals with overactive bladder may feel distress, embarrassment, inconvenience, loss of self-esteem and self-control. There will also be an effect on the sufferers personal relationships with others. […] Several treatment options exist to help manage your OAB symptoms. The first step is communicating with your doctor and obtaining the right diagnosis.
  • #28 Overactive bladder: Do symptoms come and go?
    https://www.medicalnewstoday.com/articles/does-overactive-bladder-come-and-go
    Overactive bladder (OAB) is a chronic condition that does not go away by itself. OAB may worsen without treatment and negatively affect a persons quality of life. […] OAB is a long lasting, chronic condition that will not resolve on its own. Without treatment, OAB may worsen. […] People with OAB may have symptoms that affect their daily life, including their relationships, work, sleep, sex life, exercise, and mental health. […] OAB causes an urgent and frequent need to urinate. It may occur due to problems with how the brain and bladder communicate or due to overactive bladder muscles. People may find their symptoms come and go or they may stay consistent. […] Without treatment, OAB may worsen as the bladder and pelvic floor muscles become weaker and thinner, increasing the frequency or severity of OAB symptoms. […] OAB does not go away on its own and may worsen without treatment.
  • #29 Diagnosing Overactive Bladder
    https://www.webmd.com/urinary-incontinence-oab/overactive-bladder-making-diagnosis
    Even though urinary leakage affects some 33 million adults in the U.S., it can be an embarrassing subject to discuss, even with your doctor. […] You might believe, as many people do, that overactive bladder is just an unpleasant but inescapable part of getting older. Actually it isnt — and there is something you can do. […] For how long has the urge or urinary incontinence been occurring? […] These OAB tests can help diagnose whether your condition has something to do with an infection or other illness, a blockage, or poorly functioning bladder muscles. Knowing the cause of your overactive bladder can help your doctor find the right treatment for you.
  • #30 Overactive Bladder? Here’s How Long Symptoms May Last
    https://www.healthline.com/health/how-long-does-overactive-bladder-last
    An overactive bladder may be temporary or become a chronic condition. How long the symptoms last may depend on factors like the underlying cause and treatment adherence. […] Some conditions may cause an overactive bladder for a few days, but these symptoms will resolve as the underlying cause is managed. In other cases, overactive bladder is a chronic condition that requires ongoing and long-term treatment. […] The duration of overactive bladder symptoms varies from person to person. The symptoms may be temporary or chronic. […] Temporary overactive bladder symptoms are often a result of medication side effects or urinary tract infections (UTIs). These symptoms typically resolve as you stop the medication or treat the UTI. […] When overactive bladder symptoms are associated with an underlying chronic condition like diabetes, neurological disorders, or age-related changes in bladder function, symptoms may last a long time.
  • #31 Urge Incontinence: Causes, Symptoms, & Treatment
    https://my.clevelandclinic.org/health/diseases/22161-urge-incontinence
    Urge incontinence is a type of urinary incontinence that causes an urgent, uncontrollable need to pee several times during the day and night. An overactive bladder causes urge incontinence. Overactive bladder is a common cause of urge incontinence. It makes your bladder muscles squeeze before you need to go. The most common cause of urge incontinence is an overactive bladder. An overactive bladder causes muscles in your bladder to squeeze (contract) more than they should. This makes you feel like you have to pee before your bladder is actually full. The main sign of urge incontinence is an urgent, uncontrollable need to pee that results in leakage. Other symptoms of overactive bladder include: Peeing more than eight times while you’re awake (frequent urination). Getting up to pee more than twice while you’re asleep (nocturia). Leaking pee before you can make it to the bathroom or just after you pee. Urge incontinence can also affect your mental health. Some people with severe urge incontinence may be afraid to go out in public. They may worry about being too far from a restroom or not knowing where the nearest restroom is when they have an urge to pee. These worries may increase your risk of stress, anxiety and depression. It’s possible you’ve had mild urge incontinence symptoms for a while. Over time, overactive bladder symptoms can get worse and become more noticeable. Urge incontinence usually doesn’t go away on its own. But treatments can help alleviate your symptoms. Without treatment, urge incontinence can get worse. You may have to go to the bathroom more often or leak larger amounts of pee.
  • #32 Overactive Bladder Syndrome Causes, Symptoms, and Treatments
    https://www.upmc.com/services/womens-health/conditions/overactive-bladder
    Overactive bladder (OAB) syndrome is a condition that causes a sudden urge to pee during the day or at night, or a need to urinate more frequently. It can result in accidental urine leakage, called incontinence. […] Doctors define overactive bladder as a sudden urge to urinate several times throughout the day and night. This urgency can lead to urinary leakage (incontinence). While this condition isn’t serious, it can lead to moments of inconvenience, embarrassment, and even urinary tract infections (UTIs). […] OAB syndrome becomes more common as you age. Symptoms often become more severe the older you get, too. […] The main symptoms of overactive bladder are: An urgent need to pee. Leaking urine when you have the urge to pee. Taking many trips to the toilet only to urinate just a little bit each time. Having a need to urinate even if you’ve just gone. The need to urinate often. Waking up to pee two or more times a night.
  • #32 Overactive Bladder Syndrome Causes, Symptoms, and Treatments
    https://www.upmc.com/services/womens-health/conditions/overactive-bladder
    If you have overactive bladder, you may have some or all of these symptoms. […] Left untreated, OAB can affect you physically and emotionally. It may get in the way of work, social life, exercise, and sleep. […] Fear of being far from a bathroom or leaking pee can make you reluctant to go far from home. This social isolation can affect relationships with friends and family, bringing about feelings of loneliness and depression. […] In addition, getting up multiple times a night can disrupt your sleep and sex life. Too little sleep can also contribute to depression. […] Physically, if you leak urine, you may develop skin problems or infections.
  • #33 Overactive BladderTexas Tech PhysiciansFacebook Logo
    https://www.texastechphysicians.com/clinics/lubbock/urology/overactive-bladder.aspx
    Overactive bladder can manifest through the following symptoms: […] Urgency: An uncontrollable urge to urinate. […] Frequency: The need to urinate more than 8 times in a 24-hour period. […] Urge Incontinence: Leakage or accidents that occur before you can reach the bathroom. […] These symptoms can significantly affect daily life and social activities, causing frustration and isolation. […] Overactive bladder can significantly impact quality of life, affecting daily activities and leading to social isolation. […] In most cases, the exact cause of OAB is unknown (idiopathic). However, several factors may contribute: […] Age-Related Changes: As people age, changes in the bladder muscle and its ability to stretch and contract may lead to OAB. […] Hormonal Changes: Particularly in postmenopausal women, decreased estrogen levels can affect bladder function.
  • #33 Overactive BladderTexas Tech PhysiciansFacebook Logo
    https://www.texastechphysicians.com/clinics/lubbock/urology/overactive-bladder.aspx
    Obesity: Excess weight increases pressure on the bladder, potentially worsening symptoms. […] Diabetes: Uncontrolled diabetes can lead to bladder irritation and nerve damage, further contributing to OAB. […] A thorough diagnosis is essential for effective treatment. […] Medications are often used to reduce OAB symptoms: […] Anticholinergics (oxybutynin, solifenacin, etc.): Help prevent bladder muscle contractions, reducing urgency. […] Beta-3 Adrenergic Agonists (mirabegron, vibegron): Relax the bladder muscle to reduce urgency and frequency. […] A trial of medication should last 4-8 weeks to determine its effectiveness. […] Overactive bladder can be a challenging condition, but with an accurate diagnosis and comprehensive treatment plan, many patients experience significant improvement.
  • #34 Do not let your life be disturbed. Stop worrying about overactive bladder! | Bangkok Hospital Headquarter
    https://www.bangkokhospital.com/en/content/overactive-bladder-disturb-the-quality-of-life
    Urinary abnormalities such as frequent urination and feeling a sudden urge to urinate might be frequently overlooked. In fact, these symptoms potentially indicate overactive bladder or OAB. Overactive bladder is a chronic medical condition which has tremendous impacts on the quality of life in both men and women. Overactive bladder affects performance of daily activities and social function such as work, traveling, physical exercise, sleep and sexual function. If this condition is left untreated, it leads to impaired quality of life accompanied by emotional distress and depression. […] Overactive bladder causes a frequent and sudden urge to urinate that may be difficult to control. Symptoms include a frequent urge to urinate and waking up at night to urinate regardless of the amount of water intake. As a result, overactive bladder significantly impairs self-confidence, increases risk of depression and other psychological effects as well as induces sleep disturbance, leading to decreased quality of life.
  • #35 Overactive Bladder – Urogynecology & Pelvic Health | UCLA Health
    https://www.uclahealth.org/medical-services/womens-pelvic-health/urinary-incontinence/overactive-bladder
    Overactive bladder syndrome (OAB) is characterized by the occurrence of urinary urgency which is a sudden compelling desire to urinate that is difficult to postpone. It is usually accompanied by frequent urination and nocturia (getting up to urinate at night during sleeping hours). It is also commonly accompanied by urgency incontinence, where urine is accidently lost with urgency. This commonly manifests as the inability to get to the bathroom on time once urgency starts. OAB is quite common and affects about 11-16% of adults to varying degrees. […] For some OAB can have a profound effect on quality of life causing disruptions at work, curtailing of social activities, reduction of sexual intimacy, and interfere with sleep. However, it is important to know that there are effective treatments for the symptoms of OAB.
  • #36 Overactive Bladder Clinical Presentation: History, Physical, Comorbidities
    https://emedicine.medscape.com/article/459340-clinical
    The clinician should ask about the following: […] Key screening questions should be asked, focusing on urgency, nocturia (3 times per night), urinary frequency (8 times per day), and urinary incontinence. Sample questions can include the following: […] A comprehensive physical examination can help to determine the nature, severity, and impact of the symptoms in patients with overactive bladder (OAB). […] Individuals with OAB and urinary incontinence may have other medical comorbidities. For instance, urinary tract infections (UTIs), skin infections and irritation, falls, and fractures are more likely in persons with OAB and urinary incontinence. […] In older women with daily urge incontinence, the risk of falls is increased by 26% and the risk of fractures, by 34%. […] Fortunately, treatment of OAB decreases the incidence of UTI and skin irritation and infection.
  • #37 Overactive Bladder > Fact Sheets > Yale Medicine
    https://www.yalemedicine.org/conditions/overactive-bladder
    Condition in which a person has a strong urge to urinate multiple times per day and/or at night. […] Symptoms include strong urge to urinate, frequent bathroom trips throughout the day and/or night. […] Overactive bladder is the medical term used to describe a condition in which you have a strong urge to urinate multiple times a day and overnight, even though your bladder is not full. People who urinate eight or more times during the day or at least twice overnight may be diagnosed with the condition. […] People with overactive bladder experience symptoms like: A sudden, strong urge to urinate, Frequent trips to the bathroom throughout the day, Nighttime awakenings to use the bathroom, Incontinence (leaking or accidents, in rare cases). […] People who seek treatment for overactive bladder are usually able to find relief from unwanted symptoms, leading to fewer feelings of urinary urgency and fewer bathroom visits. […] People with overactive bladder who suffer silently dont recover on their own; their quality of life will not improve without treatment.
  • #38 Overactive Bladder – Your Pelvic Floor
    https://www.yourpelvicfloor.org/conditions/overactive-bladder/
    There are many different treatments available for OAB. There are also changes that you can make to your lifestyle which can significantly improve your symptoms. […] Bladder training aims to help you hold more urine in your bladder by going to the toilet less often. It involves gradually increasing the time between visits to the toilet and trying to hold on for a little longer if you experience the urge to empty your bladder. […] The medications are designed to enable you to hold on for longer, reduce how often you need to go to the toilet (both during the day and night) and to reduce leaking. […] However, a small number will have symptoms that persist despite these treatments. In this case, the following treatments may be offered: Botulinum toxin can be injected into the bladder via a telescope, under local anesthetic. It causes relaxation of the bladder muscle, helping with urgency and allowing the bladder to store more urine.
  • #38 Overactive Bladder – Your Pelvic Floor
    https://www.yourpelvicfloor.org/conditions/overactive-bladder/
    Your doctor will be able to give you full information about the most suitable treatments for you. It may be that you are never fully cured of your overactive bladder symptoms, but there are a great number of treatments that can help you to manage your symptoms so that your life is not controlled by your bladder.
  • #39 The Difference Between Overactive Bladder and UTI – Advanced Gynecology
    https://www.advancedgynecology.com/blog/difference-between-overactive-bladder-uti
    – Diet and exercise […] – Weight loss, if indicated […] – Reducing or eliminating caffeine and alcohol […] – Stopping smoking, if you’re a smoker […] – Kegel exercises to strengthen the pelvic floor muscles […] – Avoiding bubble baths and harsh soaps […] – Managing chronic illnesses that may be linked to symptoms, such as diabetes. […] – Scheduling bathroom times to retrain the bladder […] – Medication to reduce bladder contractions
  • #40 10 Things We Wish Everyone Understood about Overactive Bladder
    https://www.greaterbostonurology.com/blog/10-things-we-wish-everyone-understood-about-overactive-bladder
    But just because something is „common” doesn’t mean it’s normal. Luckily, there are ways to help improve OAB symptoms. […] Certain foods and drinks can irritate the bladder wall. Things like caffeine, carbonated beverages, drinks containing sugar or sugar alternatives, citrus, and alcohol are some of the biggest offenders. […] We focus primarily on dietary and lifestyle modifications along with pelvic floor physical therapy as a first-line approach to treatment. A lot of times, these changes can improve OAB symptoms significantly. […] As described above, various treatments can help improve a patient’s OAB symptoms and quality of life. Talk to your primary care physician or ask for a referral to a local urologist or urogynecologist to discuss treatment options that may be best for you.
  • #41 What are the Symptoms of an Overactive Bladder? | Axonics®
    https://www.axonics.com/patients/about-your-symptoms/overactive-bladder/
    If you answered Yes to any of these questions, you may suffer from overactive bladder. The good news is that there are overactive bladder treatment options for controlling your symptoms. Axonics Therapy is an advanced solution to treat your overactive bladder symptoms. This therapy is a clinically proven solution to help people regain urinary control. […] Overactive bladder is a term that refers to a condition where patients have a lot of urgency to use the bathroom. They’ll often present with urinary frequency and some patients will also leak urine associated with that urge. Oftentimes patients will say, if they just had a few more seconds to get to the bathroom, they’d be good. […] In general, with OAB, we’ll start with conservative therapies: avoiding bladder irritants (such as caffeine and carbonated beverages) and making behavioral modifications (like going to the bathroom on a regular interval, even if somebody doesn’t have an urge to go). Doing some of these different strategies can be very helpful. Oftentimes, we’ll also incorporate a medication into the therapy to see if that gets the patient the results they are looking for. […] Patients can suffer from dual incontinence. Dual incontinence is when a patient is experiencing both bladder and bowel control symptoms.
  • #42 Overactive Bladder Treatment – Brigham and Women’s Hospital
    https://www.brighamandwomens.org/obgyn/urogynecology/overactive-bladder
    Commonly used medications for OAB are known as anticholinergics. There are several available by prescription and several are now available as generics. Common side effects of these medications are dry eyes / mouth and constipation. Of note, some of these medications may not be appropriate in older women with memory loss. One medication, called Trospium (Sanctura), is formulated to reduce crossing into the brain and may be more suitable for patients with memory loss. A newer medication, called Mirabegron (Myrbetriq), is also available. This medication works differently from the anticholinergics and is not associated with dry eyes/mouth or constipation. However, it may raise blood pressure, and may not be a good option for patients with advanced cardiovascular disease. […] PTNS is designed to treat OAB symptoms by slowing down and softening signals to and from the bladder.
  • #42 Overactive Bladder Treatment – Brigham and Women’s Hospital
    https://www.brighamandwomens.org/obgyn/urogynecology/overactive-bladder
    Women with OAB commonly experience a sudden and strong desire (urgency) to urinate that cannot be delayed. Some women with OAB lose urine on the way to the bathroom. Others may not actually lose urine but have urinary urgency, frequency (going to the bathroom more than normal), or nocturia (getting up more than once or twice to urinate at night). Involuntary bladder contractions are usually the underlying cause of OAB. […] With OAB, it is difficult to control the urinary urgency when the bladder is full. This appears to be caused by a communication problem between the brain and the bladder but we don’t understand this completely. OAB is a chronic condition like diabetes and high blood pressure. The treatment is long term, but good control is achievable. Many women with OAB also have stress urinary incontinence (loss of urine with cough, sneeze, or activity).
  • #43 Overactive bladder – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/overactive-bladder/diagnosis-treatment/drc-20355721
    If you have unusual urges to urinate, your healthcare professional checks for an infection or blood in your urine. Your health professional also may check to see if you’re emptying your bladder all the way when you urinate. […] Remaining urine in the bladder, called postvoid residual urine, can cause symptoms like those of an overactive bladder. […] A mix of treatments may be best to relieve overactive bladder symptoms. […] Behavioral therapies are the first choice in helping manage an overactive bladder. They often work and have no side effects. […] Medicines that relax the bladder can help relieve symptoms of overactive bladder and reduce episodes of urge incontinence. […] Common side effects of most of these drugs include dry eyes and dry mouth. […] Studies show that Botox may help severe urge incontinence.
  • #43 Overactive bladder – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/overactive-bladder/diagnosis-treatment/drc-20355721
    Mild electrical pulses to the bladder nerves can improve overactive bladder symptoms. […] Surgery to treat overactive bladder is only for people with severe symptoms who don’t respond to other treatments. The goal is to improve the bladder’s ability to store urine and reduce pressure in the bladder.
  • #44 Overactive bladder | UM Health-Sparrow
    https://www.uofmhealthsparrow.org/departments-conditions/conditions/overactive-bladder
    Aging increases the risk of overactive bladder. So does being female. Conditions such as enlarged prostate and diabetes also can increase the risk. […] Any type of incontinence can affect quality of life. If your overactive bladder symptoms disrupt your life, you might also have: Anxiety. Emotional distress or depression. Sexual problems. Sleep disturbances and interrupted sleep cycles. […] A mix of treatments may be best to relieve overactive bladder symptoms. […] Behavioral therapies are the first choice in helping manage an overactive bladder. They often work and have no side effects. […] Medicines that relax the bladder can help relieve symptoms of overactive bladder and reduce episodes of urge incontinence. […] OnabotulinumtoxinA (ON-ah-boch-yoo-lih-num-tox-in-A), also called Botox, is a protein from the bacteria that cause botulism illness. Small doses shot into bladder tissues can relax the muscles and increase the amount of urine the bladder can hold.
  • #45 Overactive Bladder – Symptoms, Causes, & Treatments
    http://www.advancedurologyinstitute.com/condition/overactive-bladder-oab/
    Botox is a minimally invasive procedure where Botox is injected into the muscles of the bladder to improve relaxation and decrease urgency, frequency, and waking up at night to urinate. […] PTNS stimulates the nerves to the bladder and decrease urgency, frequency, and waking up at night to urinate.
  • #46 AUA Releases Guideline on Diagnosis and Treatment of Overactive Bladder | AAFP
    https://www.aafp.org/pubs/afp/issues/2013/0601/p800.html
    Overactive bladder is characterized by urinary symptoms including urgency, frequency, and nocturia, with or without urge incontinence. The prevalence and severity of symptoms increase with age, and most patients have symptoms for years. […] Overactive bladder is a complex of symptoms that generally do not affect survival, but may compromise quality of life. […] Patients who have symptoms that are refractory to behavioral and medical therapy should be evaluated by a subspecialist if they desire additional therapy. […] Sacral neuromodulation may be offered as third-line treatment in select patients with severe refractory symptoms or in those who are not candidates for second-line therapy and are willing to undergo surgery.
  • #47 Overactive Bladder (OAB): Symptoms and Treatment
    https://patient.info/doctor/overactive-bladder
    Overactive bladder (OAB) syndrome is characterised by urgency, often with frequency and nocturia and sometimes leakage (urge incontinence). […] Overactive bladder syndrome symptoms include a sudden urge to pass urine that is very difficult to delay and may be associated with leakage. Other features include: Frequency of micturition. Nocturia. Abdominal discomfort. Urge incontinence (more common in women). […] Behavioural therapy combined with drug treatment is often effective, with over 80% of cases improved and with excellent long-term results.