Mesenteritis stwardniająca
Charakterystyka, pielęgnacja i opieka
Stwardniające zapalenie krezki (sclerosing mesenteritis, SM) to rzadka, przewlekła choroba charakteryzująca się zapaleniem i włóknieniem tkanki krezkowej, co może prowadzić do objawów takich jak przewlekły ból brzucha, wzdęcia, biegunka, utrata masy ciała, wymioty, gorączka, tworzenie masy wewnątrzbrzusznej, niedrożność jelit oraz wodobrzusze mleczowe. Etiologia pozostaje niejasna, choć wiąże się z przebytymi operacjami, urazami, chorobami autoimmunologicznymi, infekcjami i nowotworami. Diagnostyka opiera się na badaniach obrazowych i wysokim podejrzeniu klinicznym, zwłaszcza u pacjentów z przewlekłą biegunką lub marskością wątroby. W niektórych przypadkach SM jest powiązane z chorobą IgG4-zależną, co ma znaczenie terapeutyczne. Leczenie farmakologiczne obejmuje niesteroidowe leki przeciwzapalne, glikokortykosteroidy (np. prednizon), leki immunosupresyjne (azatiopryna, cyklofosfamid), tamoksyfen, kolchicynę, talidomid i progesteron, a w przypadkach powikłanych niedrożnością jelit – interwencję chirurgiczną.
- Wprowadzenie do stwardniającego zapalenia krezki
- Objawy i manifestacje kliniczne
- Opieka pielęgnacyjna nad pacjentem z SM
- Monitorowanie pacjentów bezobjawowych
- Podejście do pacjentów objawowych
- Opieka nad pacjentem poddawanym farmakoterapii
- Opieka nad pacjentem poddawanym leczeniu chirurgicznemu
- Podejście interdyscyplinarne w opiece nad pacjentem z SM
- Szczególne aspekty opieki w zależności od współistniejących chorób
- Stwardniające zapalenie krezki związane z IgG4
- Stwardniające zapalenie krezki u pacjentów z marskością wątroby
- Stwardniające zapalenie krezki u pacjentów z zespołem antyfosfolipidowym
- Wyzwania w opiece i sposoby ich przezwyciężania
- Rozwój zawodowy personelu pielęgniarskiego
- Podsumowanie kluczowych aspektów opieki
Wprowadzenie do stwardniającego zapalenia krezki
Stwardniające zapalenie krezki (sclerosing mesenteritis, SM) to rzadka choroba charakteryzująca się przewlekłym zapaleniem krezki – tkanki, która utrzymuje jelito cienkie na swoim miejscu. W przebiegu choroby dochodzi do stanu zapalnego, a następnie tworzenia się tkanki bliznowatej w obrębie krezki12. Stan ten może prowadzić do różnorodnych objawów, a w rzadkich przypadkach może powodować niedrożność przewodu pokarmowego, wymagającą interwencji chirurgicznej3.
Choroba ta znana jest również pod innymi nazwami, takimi jak zapalenie krezki tkanki tłuszczowej (mesenteric panniculitis) lub lipodystrofia krezki (mesenteric lipodystrophy)4. Etiologia stwardniającego zapalenia krezki pozostaje niejasna, choć uważa się, że może być związana z przebytymi operacjami jamy brzusznej, urazami, zaburzeniami autoimmunologicznymi, infekcjami lub nowotworami56.
Objawy i manifestacje kliniczne
Manifestacje kliniczne stwardniającego zapalenia krezki są różnorodne i mogą obejmować:78
- Przewlekły ból brzucha
- Wzdęcia
- Biegunkę
- Utratę masy ciała
- Wymioty
- Gorączkę
- Tworzenie się masy wewnątrzbrzusznej
- Niedrożność jelit
- Wodobrzusze mleczowe (chylous ascites)
Należy podkreślić, że niektórzy pacjenci mogą nie doświadczać żadnych objawów i mogą nigdy nie wymagać leczenia910. W wielu przypadkach rozpoznanie stwardniającego zapalenia krezki następuje przypadkowo, podczas diagnostyki z powodu innej choroby11.
Stwardniające zapalenie krezki może być również powiązane z przewlekłą biegunką, co sugeruje, że należy rozważyć tę jednostkę chorobową w diagnostyce różnicowej przewlekłej biegunki i w razie wskazań wykonać odpowiednie badania obrazowe12.
Opieka pielęgnacyjna nad pacjentem z SM
Monitorowanie pacjentów bezobjawowych
W przypadku pacjentów, którzy nie doświadczają dyskomfortu związanego ze stwardniającym zapaleniem krezki, leczenie może nie być konieczne. Zamiast tego, zaleca się okresowe badania obrazowe w celu monitorowania stanu choroby1314. Personel pielęgniarski powinien edukować pacjentów na temat znaczenia regularnych kontroli i badań obrazowych, nawet przy braku objawów klinicznych.
Podejście do pacjentów objawowych
Jeśli pacjent zaczyna doświadczać objawów stwardniającego zapalenia krezki, może być konieczne rozpoczęcie leczenia1516. Celem terapii jest kontrola stanu zapalnego przy użyciu odpowiednich leków17.
Opieka pielęgniarska nad pacjentami objawowymi powinna obejmować:1819
- Regularną ocenę nasilenia objawów
- Monitorowanie skuteczności leczenia przeciwzapalnego
- Edukację pacjenta w zakresie przyjmowania leków i potencjalnych skutków ubocznych
- Wsparcie psychologiczne w radzeniu sobie z przewlekłą chorobą
- Rozpoznawanie powikłań wymagających pilnej interwencji (np. niedrożność jelit)
Opieka nad pacjentem poddawanym farmakoterapii
Leczenie farmakologiczne stwardniającego zapalenia krezki ma na celu kontrolę stanu zapalnego20. W leczeniu stosuje się różne leki, w tym:2122
- Niesteroidowe leki przeciwzapalne (NLPZ)
- Glikokortykosteroidy (np. prednizon)
- Leki immunosupresyjne (azatiopryna, cyklofosfamid)
- Tamoksyfen
- Kolchicynę
- Talidomid
- Progesteron
Personel pielęgniarski powinien monitorować skuteczność leczenia oraz występowanie potencjalnych działań niepożądanych stosowanych leków. Szczególną uwagę należy zwrócić na pacjentów z współistniejącymi chorobami, takimi jak cukrzyca, gdyż leczenie glikokortykosteroidami może wpływać na kontrolę glikemii23.
Co ciekawe, w przypadku pacjentów z cukrzycą i stwardniającym zapaleniem krezki, leczenie glikokortykosteroidami, które zwykle powoduje znaczny wzrost stężenia glukozy we krwi, paradoksalnie może prowadzić do poprawy kontroli glikemii24. Jest to istotna obserwacja kliniczna, którą personel pielęgniarski powinien uwzględnić podczas monitorowania pacjentów z tymi współistniejącymi schorzeniami.
Opieka nad pacjentem poddawanym leczeniu chirurgicznemu
Interwencja chirurgiczna może być konieczna w przypadkach, gdy tkanka bliznowata blokuje przepływ pokarmu przez przewód pokarmowy252627. Leczenie chirurgiczne jest również zalecane w przypadkach nieustępujących na leczenie zachowawcze oraz w przypadkach powikłanych niedrożnością jelit28.
Opieka pielęgniarska nad pacjentem poddawanym leczeniu chirurgicznemu powinna obejmować:2930
- Przygotowanie przedoperacyjne
- Monitorowanie stanu pacjenta po zabiegu
- Ocenę bólu i odpowiednie postępowanie przeciwbólowe
- Wczesne rozpoznawanie powikłań pooperacyjnych
- Rehabilitację i wsparcie w powrocie do codziennych aktywności
Podejście interdyscyplinarne w opiece nad pacjentem z SM
Opieka nad pacjentem ze stwardniającym zapaleniem krezki wymaga podejścia interdyscyplinarnego, w którym personel pielęgniarski odgrywa kluczową rolę3132. Współpraca między różnymi specjalistami, w tym gastroenterologami, chirurgami, radiologami, pielęgniarkami i pracownikami socjalnymi, jest niezbędna do zapewnienia kompleksowej opieki.
W idealnym modelu opieki, menadżer opieki (care manager) może koordynować działania zespołu terapeutycznego i wspierać pacjenta w rozwoju umiejętności samodzielnego zarządzania swoim zdrowiem33. Interwencje menadżera opieki powinny być ukierunkowane na zwiększenie samodzielności pacjenta i wspieranie go w rozwoju pewności siebie w skutecznym samodzielnym zarządzaniu swoim zdrowiem34.
Edukacja i wsparcie pacjenta
Rola personelu pielęgniarskiego w edukacji i wsparciu pacjentów ze stwardniającym zapaleniem krezki jest niezwykle istotna. Edukacja powinna obejmować:35
- Informacje na temat choroby, jej przebiegu i potencjalnych powikłań
- Znaczenie regularnych badań kontrolnych
- Rozpoznawanie objawów wymagających natychmiastowej konsultacji medycznej
- Prawidłowe stosowanie zaleconych leków
- Strategie radzenia sobie z bólem i innymi objawami
- Aspekty związane z jakością życia i funkcjonowaniem psychospołecznym
Personel pielęgniarski powinien uwzględniać nie tylko medyczne, ale także społeczne, behawioralne i emocjonalne aspekty życia z przewlekłą chorobą36. Spotkania z pacjentem powinny mieć szeroką perspektywę i rozważać wpływ, jaki życie z przewlekłą chorobą może mieć na jakość życia pacjenta.
Szczególne aspekty opieki w zależności od współistniejących chorób
Stwardniające zapalenie krezki związane z IgG4
Stwardniające zapalenie krezki może być związane z chorobą IgG4-zależną (IgG4-related disease, IgG4-RD). W takich przypadkach, leczenie glikokortykosteroidami wykazuje szczególnie dobrą skuteczność37. Zaleca się uwzględnienie stwardniającego zapalenia krezki związanego z IgG4 w diagnostyce różnicowej u każdego pacjenta z podwyższonym poziomem IgG4, nawracającymi bólami brzucha i/lub masami krezkowym38.
Personel pielęgniarski powinien być świadomy tej szczególnej postaci choroby i jej potencjalnych powiązań z zapaleniem tarczycy Hashimoto i rakiem brodawkowatym tarczycy39.
Stwardniające zapalenie krezki u pacjentów z marskością wątroby
U pacjentów z marskością wątroby, nawet wyrównaną i niepowikłaną, podstępny początek objawów niedrożności jelit powinien uwzględniać stwardniające zapalenie krezki w diagnostyce różnicowej40. Personel pielęgniarski powinien zwracać szczególną uwagę na te objawy u pacjentów z chorobami wątroby.
Stwardniające zapalenie krezki u pacjentów z zespołem antyfosfolipidowym
U pacjentów ze stwardniającym zapaleniem krezki należy badać wszelkie stany, które mogą powodować przewlekłe zapalenie tkanki krezkowej. Zespół antyfosfolipidowy może być związany z przewlekłą aktywnością zakrzepową, która może przyczyniać się do przewlekłego niedokrwienia krezki4142.
Wyzwania w opiece i sposoby ich przezwyciężania
Trudności diagnostyczne
Rozpoznanie stwardniającego zapalenia krezki stanowi wyzwanie diagnostyczne i wymaga wysokiego poziomu podejrzenia klinicznego43. Może być ułatwione przez historię pacjenta, istniejące czynniki predysponujące, różne parametry biochemiczne i obrazowanie radiologiczne44.
Lepsza świadomość tej rzadkiej jednostki klinicznej i znajomość wyników badań obrazowych może ułatwić diagnostykę przedoperacyjną, co jest kluczowe dla wyboru odpowiedniej interwencji chirurgicznej lub nawet uniknięcia potrzeby operacji na rzecz leczenia immunosupresyjnego45.
Brak specyficznych wytycznych leczenia
Ze względu na rzadkość występowania choroby, nie ma specyficznych wytycznych dotyczących leczenia stwardniającego zapalenia krezki4647. Ta niepewność może stanowić wyzwanie dla personelu pielęgniarskiego w planowaniu opieki nad pacjentem. Personel powinien być na bieżąco z najnowszymi doniesieniami na temat leczenia tej choroby i indywidualizować opiekę w oparciu o potrzeby pacjenta.
Stworzenie kompleksowego planu opieki
Personel pielęgniarski powinien być w stanie rozwijać plan leczenia pacjentów ze stwardniającym zapaleniem krezki w oparciu o nasilenie objawów, choroby współistniejące i/lub powikłania48. Plan opieki powinien być kompleksowy i uwzględniać wszystkie aspekty życia pacjenta.
Rozwój zawodowy personelu pielęgniarskiego
Personel pielęgniarski zajmujący się pacjentami ze stwardniającym zapaleniem krezki powinien dążyć do ciągłego rozwoju zawodowego. Dostępne są różne formy kształcenia, w tym programy ustawicznego kształcenia medycznego (CME), które umożliwiają zdobycie wiedzy na temat rozpoznawania czynników ryzyka stwardniającego zapalenia krezki, jego objawów klinicznych oraz opracowywania planów leczenia49.
Pomyślne ukończenie takich działań edukacyjnych może umożliwić uczestnikom zdobycie punktów w ramach programów utrzymania certyfikacji (MOC) różnych towarzystw medycznych50. Dla pielęgniarek dostępne są również certyfikaty uczestnictwa, które mogą być wykorzystane do ubiegania się o punkty zgodnie z wymogami rad pielęgniarskich, towarzystw specjalistycznych lub innych stowarzyszeń zawodowych51.
Podsumowanie kluczowych aspektów opieki
Opieka pielęgniarska nad pacjentem ze stwardniającym zapaleniem krezki powinna być kompleksowa i zindywidualizowana. Kluczowe aspekty opieki obejmują:525354
- Monitorowanie pacjentów bezobjawowych poprzez regularne badania obrazowe
- Wdrażanie odpowiedniego leczenia u pacjentów objawowych
- Edukację pacjenta na temat choroby i jej leczenia
- Wsparcie psychospołeczne
- Rozpoznawanie powikłań wymagających interwencji chirurgicznej
- Interdyscyplinarne podejście do opieki
- Ciągły rozwój zawodowy personelu pielęgniarskiego
Personel pielęgniarski odgrywa kluczową rolę w opiece nad pacjentami ze stwardniającym zapaleniem krezki, przyczyniając się do poprawy jakości ich życia i skutecznego zarządzania chorobą.
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Materiały źródłowe
- #1 Sclerosing mesenteritis – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/sclerosing-mesenteritis/symptoms-causes/syc-20355087
Sclerosing mesenteritis care at Mayo Clinic […] Sclerosing mesenteritis is a condition in which tissue that holds the small intestines in place, called the mesentery, becomes inflamed and forms scar tissue. […] In rare cases, scar tissue formed by sclerosing mesenteritis can block food from moving through the digestive tract. In this case, you may need surgery.
- #2 Mayo Clinic Health Library – Sclerosing mesenteritis | Swiss Medical Networkhttps://www.swissmedical.net/en/healtcare-library/con-20213811
Sclerosing mesenteritis is a rare condition that may lead to blockage in the small intestine. […] Sclerosing mesenteritis is a condition in which tissue that holds the small intestines in place, called the mesentery, becomes inflamed and forms scar tissue. […] Sclerosing mesenteritis can cause belly pain, vomiting, bloating, diarrhea and fever. But some people experience no symptoms and may never need treatment. […] In rare cases, scar tissue formed by sclerosing mesenteritis can block food from moving through the digestive tract. In this case, you may need surgery. […] If you are not experiencing discomfort from sclerosing mesenteritis, you may not need treatment. Instead, occasional imaging tests may be recommended to monitor your condition. […] If you begin to experience symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] You may need surgery if the scar tissue blocks food from moving through your digestive tract.
- #3 Sclerosing mesenteritis | Beacon Health Systemhttps://www.beaconhealthsystem.org/library/diseases-and-conditions/sclerosing-mesenteritis?content_id=CON-20213811
Sclerosing mesenteritis is a rare condition that may lead to blockage in the small intestine. […] Sclerosing mesenteritis can cause belly pain, vomiting, bloating, diarrhea and fever. But some people experience no symptoms and may never need treatment. […] In rare cases, scar tissue formed by sclerosing mesenteritis can block food from moving through the digestive tract. In this case, you may need surgery. […] If you are not experiencing discomfort from sclerosing mesenteritis, you may not need treatment. Instead, occasional imaging tests may be recommended to monitor your condition. […] If you begin to experience symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] You may need surgery if the scar tissue blocks food from moving through your digestive tract.
- #4 Sclerosing mesenteritis:an uncommon cause of chronic abdominal pain – MedCrave onlinehttps://medcraveonline.com/GHOA/sclerosing-mesenteritisan-uncommon-cause-of-chronic-abdominal-pain.html
Sclerosing mesenteritis (SM), also known as mesenteric panniculitis or mesenteric lipodystrophy, is a rare disease that affects the mesentery of the small intestine. […] Asymptomatic patients typically require no treatment, while refractory cases have shown some symptomatic improvement with immunosuppressive therapy. […] Due to the rarity of the condition, there are no specific guidelines for treatment of SM however steroids, colchicine, azathioprine, thalidomide, cyclophosphamide and progesterone have been tried, however asymptomatic cases don’t need therapy. Surgical resection is recommended for non-resolving cases and complicated by bowel obstruction. […] A treatment algorithm was prepared by Akram after review on 92 cases. Asymptomatic patients with incidental diagnosis do not need treatment. Patients with features of bowel obstruction need to undergo surgical treatment followed by tamoxifen plus tapering dose of steroids if there is persistence of symptoms.
- #5 Idiopathic sclerosing mesenteritis presenting with small bowel volvulus in a patient with antiphospholipid syndrome: A case reporthttps://wjgnet.com/2307-8960/abstract/v11/i14/3304.htm
Sclerosing mesenteritis is a rare disorder involving inflammation of the mesentery. Its etiology remains unclear, but it is believed to be associated with previous abdominal surgery, trauma, autoimmune disorders, infection, or malignancy. Clinical manifestations of sclerosing mesenteritis are varied and include chronic abdominal pain, bloating, diarrhea, weight loss, formation of an intra-abdominal mass, bowel obstruction, and chylous ascites. […] Sclerosing mesenteritis is a rare condition, and patients with no clear etiology should be considered for treatment with immunosuppressive therapy. […] In patients with sclerosing mesenteritis, any condition that causes chronic inflammation of mesenteric tissue should be investigated. Antiphospholipid syndrome may be linked with chronic thrombotic activity that can contribute to chronic ischemia of the mesentery. Patients with uncertain etiology should be considered for treatment with immunosuppressive therapy.
- #6 Idiopathic sclerosing mesenteritis presenting with small bowel volvulus in a patient with antiphospholipid syndrome: A case reporthttps://www.wjgnet.com/2307-8960/full/v11/i14/3304.htm
Sclerosing mesenteritis is a rare disorder involving inflammation of the mesentery. Its etiology remains unclear, but it is believed to be associated with previous abdominal surgery, trauma, autoimmune disorders, infection, or malignancy. Clinical manifestations of sclerosing mesenteritis are varied and include chronic abdominal pain, bloating, diarrhea, weight loss, formation of an intra-abdominal mass, bowel obstruction, and chylous ascites. […] Sclerosing mesenteritis is a rare condition, and patients with no clear etiology should be considered for treatment with immunosuppressive therapy. […] In patients with sclerosing mesenteritis, any condition that causes chronic inflammation of mesenteric tissue should be investigated. Antiphospholipid syndrome may be linked with chronic thrombotic activity that can contribute to chronic ischemia of the mesentery. Patients with uncertain etiology should be considered for treatment with immunosuppressive therapy.
- #7 Idiopathic sclerosing mesenteritis presenting with small bowel volvulus in a patient with antiphospholipid syndrome: A case reporthttps://wjgnet.com/2307-8960/abstract/v11/i14/3304.htm
Sclerosing mesenteritis is a rare disorder involving inflammation of the mesentery. Its etiology remains unclear, but it is believed to be associated with previous abdominal surgery, trauma, autoimmune disorders, infection, or malignancy. Clinical manifestations of sclerosing mesenteritis are varied and include chronic abdominal pain, bloating, diarrhea, weight loss, formation of an intra-abdominal mass, bowel obstruction, and chylous ascites. […] Sclerosing mesenteritis is a rare condition, and patients with no clear etiology should be considered for treatment with immunosuppressive therapy. […] In patients with sclerosing mesenteritis, any condition that causes chronic inflammation of mesenteric tissue should be investigated. Antiphospholipid syndrome may be linked with chronic thrombotic activity that can contribute to chronic ischemia of the mesentery. Patients with uncertain etiology should be considered for treatment with immunosuppressive therapy.
- #8 Idiopathic sclerosing mesenteritis presenting with small bowel volvulus in a patient with antiphospholipid syndrome: A case reporthttps://www.wjgnet.com/2307-8960/full/v11/i14/3304.htm
Sclerosing mesenteritis is a rare disorder involving inflammation of the mesentery. Its etiology remains unclear, but it is believed to be associated with previous abdominal surgery, trauma, autoimmune disorders, infection, or malignancy. Clinical manifestations of sclerosing mesenteritis are varied and include chronic abdominal pain, bloating, diarrhea, weight loss, formation of an intra-abdominal mass, bowel obstruction, and chylous ascites. […] Sclerosing mesenteritis is a rare condition, and patients with no clear etiology should be considered for treatment with immunosuppressive therapy. […] In patients with sclerosing mesenteritis, any condition that causes chronic inflammation of mesenteric tissue should be investigated. Antiphospholipid syndrome may be linked with chronic thrombotic activity that can contribute to chronic ischemia of the mesentery. Patients with uncertain etiology should be considered for treatment with immunosuppressive therapy.
- #9 Sclerosing mesenteritis | UM Health-Sparrowhttps://www.uofmhealthsparrow.org/departments-conditions/conditions/sclerosing-mesenteritis
Sclerosing mesenteritis can cause belly pain, vomiting, bloating, diarrhea and fever. But some people experience no symptoms and may never need treatment. […] You may be diagnosed with sclerosing mesenteritis while you are receiving care for another condition. If you are not experiencing discomfort from sclerosing mesenteritis, you may not need treatment. Instead, occasional imaging tests may be recommended to monitor your condition. […] If you begin to experience symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] You may need surgery if the scar tissue blocks food from moving through your digestive tract.
- #10 Sclerosing mesenteritishttps://www.mymlc.com/health-information/diseases-and-conditions/s/sclerosing-mesenteritis/
Sclerosing mesenteritis can cause abdominal pain, vomiting, bloating, diarrhea and fever. But some people experience no signs and symptoms and may never need treatment. […] You may be diagnosed with sclerosing mesenteritis while you are receiving care for another condition. If you are not experiencing discomfort from sclerosing mesenteritis, you may not require treatment. Instead, your doctor may recommend periodic imaging tests to monitor your condition. […] If you begin to experience signs and symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] Medications for sclerosing mesenteritis are intended to control inflammation. […] If sclerosing mesenteritis advances to block the flow of food through your digestive system, you may need surgery to remove the blockage.
- #11 Sclerosing mesenteritis | UM Health-Sparrowhttps://www.uofmhealthsparrow.org/departments-conditions/conditions/sclerosing-mesenteritis
Sclerosing mesenteritis can cause belly pain, vomiting, bloating, diarrhea and fever. But some people experience no symptoms and may never need treatment. […] You may be diagnosed with sclerosing mesenteritis while you are receiving care for another condition. If you are not experiencing discomfort from sclerosing mesenteritis, you may not need treatment. Instead, occasional imaging tests may be recommended to monitor your condition. […] If you begin to experience symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] You may need surgery if the scar tissue blocks food from moving through your digestive tract.
- #12https://journals.lww.com/ajg/fulltext/2022/10002/s3391_chronic_sclerosing_mesenteritis__an_uncommon.3391.aspx
Sclerosing mesenteritis is an uncommon condition where chronic inflammation and necrosis of mesenteric adipose tissue leads to progressive fibrosis. […] This case highlights the association between sclerosing mesenteritis and chronic diarrhea. […] Therefore, it is prudent to consider this disease in the workup of chronic diarrhea and obtain imaging when indicated, as these patients may qualify for advanced therapies. […] Since immunosuppressive agents are the standard of care for symptomatic sclerosing mesenteritis, the escalation of this patients diarrhea to a point requiring hospitalization suggests that diarrhea may be sufficient justification for initiation of immunosuppressive therapy in diagnosed patients, although further research is needed to establish this utility.
- #13 Sclerosing mesenteritis – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/sclerosing-mesenteritis/diagnosis-treatment/drc-20450343
Our caring team of Mayo Clinic experts can help you with your sclerosing mesenteritis-related health concerns […] If you are not experiencing discomfort from sclerosing mesenteritis, you may not need treatment. Instead, occasional imaging tests may be recommended to monitor your condition. […] If you begin to experience symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] You may need surgery if the scar tissue blocks food from moving through your digestive tract.
- #14 Sclerosing mesenteritis | UM Health-Sparrowhttps://www.uofmhealthsparrow.org/departments-conditions/conditions/sclerosing-mesenteritis
Sclerosing mesenteritis can cause belly pain, vomiting, bloating, diarrhea and fever. But some people experience no symptoms and may never need treatment. […] You may be diagnosed with sclerosing mesenteritis while you are receiving care for another condition. If you are not experiencing discomfort from sclerosing mesenteritis, you may not need treatment. Instead, occasional imaging tests may be recommended to monitor your condition. […] If you begin to experience symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] You may need surgery if the scar tissue blocks food from moving through your digestive tract.
- #15 Sclerosing mesenteritis – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/sclerosing-mesenteritis/diagnosis-treatment/drc-20450343
Our caring team of Mayo Clinic experts can help you with your sclerosing mesenteritis-related health concerns […] If you are not experiencing discomfort from sclerosing mesenteritis, you may not need treatment. Instead, occasional imaging tests may be recommended to monitor your condition. […] If you begin to experience symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] You may need surgery if the scar tissue blocks food from moving through your digestive tract.
- #16 Sclerosing mesenteritis – Medicine.comhttps://www.medicine.com/topic/sclerosing-mesenteritis
You may be diagnosed with sclerosing mesenteritis while you are receiving care for another condition. If you are not experiencing discomfort from sclerosing mesenteritis, you may not require treatment. Instead, your doctor may recommend periodic imaging tests to monitor your condition. […] If you begin to experience signs and symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] Medications for sclerosing mesenteritis are intended to control inflammation. […] If sclerosing mesenteritis advances to block the flow of food through your digestive system, you may need surgery to remove the blockage.
- #17 Sclerosing mesenteritishttps://www.mymlc.com/health-information/diseases-and-conditions/s/sclerosing-mesenteritis/
Sclerosing mesenteritis can cause abdominal pain, vomiting, bloating, diarrhea and fever. But some people experience no signs and symptoms and may never need treatment. […] You may be diagnosed with sclerosing mesenteritis while you are receiving care for another condition. If you are not experiencing discomfort from sclerosing mesenteritis, you may not require treatment. Instead, your doctor may recommend periodic imaging tests to monitor your condition. […] If you begin to experience signs and symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] Medications for sclerosing mesenteritis are intended to control inflammation. […] If sclerosing mesenteritis advances to block the flow of food through your digestive system, you may need surgery to remove the blockage.
- #18https://www.alliedacademies.org/articles/igg4related-sclerosing-mesenteritis-and-its-possible-relation-to-papillarythyroid-carcinoma-in-a-27yearold-egyptian-woman-8629.html
Sclerosing mesenteritis (SM) is a rare fibro inflammatory disease unknown etiology involves the small bowel mesentry, most frequently observed in middle aged and older men. […] Management ranges from left untreated in asymptomatic patients to surgical exploration in life threatening complications as bowel obstruction or perforation or if there is a suspicion of malignancy. Medical treatment including corticosteroids, tamoxifen, cyclophosphamide and azathioprine has also shown good results especially corticosteroids if SM is due to IgG4- RD. […] Building on the specific treatment recommendations given to patients by their doctor, meetings between the care manager and the patient could take a broad perspective and consider the medical, social, behavioral, and emotional impact that living with a chronic conditioner reducing a health risk might have on the patients quality of life.
- #19https://www.alliedacademies.org/articles/igg4related-sclerosing-mesenteritis-and-its-possible-relation-to-papillarythyroid-carcinoma-in-a-27yearold-egyptian-woman-8629.html
Each of the care managers interventions was intended to increase patient empowerment, supporting patients to develop the confidence to effectively self-manage their health. […] Unfortunately, in this case like many others we dont have this system of care manager, social workers, actually, her husband which is a police officer did well the role of care manager. […] We recommend inclusion of IgG related sclerosis mesenteritis in every case of IgG4 recurrent abdominal pain and/or mesenteric masses. […] IgG4-RD may be associated with SM, Hashimotos thyroiditis, and papillary thyroid carcinoma. Although SM may be difficult to be diagnosed without histopathology, yet, it should be considered in any abdominal pain or mesentric mass to avoid unnecessary surgical interventions especially with good response to corticosteroids.
- #20 Sclerosing mesenteritis – Medicine.comhttps://www.medicine.com/topic/sclerosing-mesenteritis
You may be diagnosed with sclerosing mesenteritis while you are receiving care for another condition. If you are not experiencing discomfort from sclerosing mesenteritis, you may not require treatment. Instead, your doctor may recommend periodic imaging tests to monitor your condition. […] If you begin to experience signs and symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] Medications for sclerosing mesenteritis are intended to control inflammation. […] If sclerosing mesenteritis advances to block the flow of food through your digestive system, you may need surgery to remove the blockage.
- #21 Sclerosing Mesenteritis Managed Conservatively With Prednisonehttps://pmc.ncbi.nlm.nih.gov/articles/PMC10040226/
The authors present the case of a middle-aged lady with two weeks of abdominal pain. […] In our patients case, she was able to be managed conservatively, without the need for surgery. This reflects the most benign and self-limiting natural history of the disease. […] Treatment for sclerosing mesenteritis typically involves medications to manage symptoms and reduce inflammation. These can include non-steroidal anti-inflammatory drugs (NSAIDs) and immunosuppressive agents. Surgery is reserved for bowel obstruction or perforation or complicated panniculitis refractory to medical treatment. […] In many cases, where the condition is not severe, conservative treatment with observation would suffice. This was the case with our patient. A similar resolution of sclerosing mesenteritis with steroid therapy is documented in the literature. […] Our patient had a relatively benign course which did not require surgical intervention but rather was able to be managed with only steroid therapy.
- #22 Sclerosing mesenteritis:an uncommon cause of chronic abdominal pain – MedCrave onlinehttps://medcraveonline.com/GHOA/sclerosing-mesenteritisan-uncommon-cause-of-chronic-abdominal-pain.html
Sclerosing mesenteritis (SM), also known as mesenteric panniculitis or mesenteric lipodystrophy, is a rare disease that affects the mesentery of the small intestine. […] Asymptomatic patients typically require no treatment, while refractory cases have shown some symptomatic improvement with immunosuppressive therapy. […] Due to the rarity of the condition, there are no specific guidelines for treatment of SM however steroids, colchicine, azathioprine, thalidomide, cyclophosphamide and progesterone have been tried, however asymptomatic cases don’t need therapy. Surgical resection is recommended for non-resolving cases and complicated by bowel obstruction. […] A treatment algorithm was prepared by Akram after review on 92 cases. Asymptomatic patients with incidental diagnosis do not need treatment. Patients with features of bowel obstruction need to undergo surgical treatment followed by tamoxifen plus tapering dose of steroids if there is persistence of symptoms.
- #23 Diabetic Man With Sclerosing Mesenteritis Experiences Glycemic Control With Steroids | MedPage Todayhttps://www.medpagetoday.com/casestudies/endocrinology/92971
Clinicians start the patient on 40-mg prednisone daily. This reduces his abdominal pain and improves glycemic control, as indicated by a lower insulin requirement (total mean daily dose of insulin of 32 IU). […] Case authors conclude that sclerosing mesenteritis should be included in the differential diagnosis of abdominal pain in diabetes patients, and considered when seeking a cause of metabolic decompensation in patients with diabetes. While glucocorticoid treatment generally results in a significant increase in blood glucose levels, it can paradoxically lead to better glycemic control in patients with sclerosing mesenteritis.
- #24 Diabetic Man With Sclerosing Mesenteritis Experiences Glycemic Control With Steroids | MedPage Todayhttps://www.medpagetoday.com/casestudies/endocrinology/92971
Clinicians start the patient on 40-mg prednisone daily. This reduces his abdominal pain and improves glycemic control, as indicated by a lower insulin requirement (total mean daily dose of insulin of 32 IU). […] Case authors conclude that sclerosing mesenteritis should be included in the differential diagnosis of abdominal pain in diabetes patients, and considered when seeking a cause of metabolic decompensation in patients with diabetes. While glucocorticoid treatment generally results in a significant increase in blood glucose levels, it can paradoxically lead to better glycemic control in patients with sclerosing mesenteritis.
- #25 Sclerosing mesenteritis – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/sclerosing-mesenteritis/diagnosis-treatment/drc-20450343
Our caring team of Mayo Clinic experts can help you with your sclerosing mesenteritis-related health concerns […] If you are not experiencing discomfort from sclerosing mesenteritis, you may not need treatment. Instead, occasional imaging tests may be recommended to monitor your condition. […] If you begin to experience symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] You may need surgery if the scar tissue blocks food from moving through your digestive tract.
- #26 Sclerosing mesenteritis – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/sclerosing-mesenteritis/symptoms-causes/syc-20355087
Sclerosing mesenteritis care at Mayo Clinic […] Sclerosing mesenteritis is a condition in which tissue that holds the small intestines in place, called the mesentery, becomes inflamed and forms scar tissue. […] In rare cases, scar tissue formed by sclerosing mesenteritis can block food from moving through the digestive tract. In this case, you may need surgery.
- #27 Mayo Clinic Health Library – Sclerosing mesenteritis | Swiss Medical Networkhttps://www.swissmedical.net/en/healtcare-library/con-20213811
Sclerosing mesenteritis is a rare condition that may lead to blockage in the small intestine. […] Sclerosing mesenteritis is a condition in which tissue that holds the small intestines in place, called the mesentery, becomes inflamed and forms scar tissue. […] Sclerosing mesenteritis can cause belly pain, vomiting, bloating, diarrhea and fever. But some people experience no symptoms and may never need treatment. […] In rare cases, scar tissue formed by sclerosing mesenteritis can block food from moving through the digestive tract. In this case, you may need surgery. […] If you are not experiencing discomfort from sclerosing mesenteritis, you may not need treatment. Instead, occasional imaging tests may be recommended to monitor your condition. […] If you begin to experience symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] You may need surgery if the scar tissue blocks food from moving through your digestive tract.
- #28 Sclerosing mesenteritis:an uncommon cause of chronic abdominal pain – MedCrave onlinehttps://medcraveonline.com/GHOA/sclerosing-mesenteritisan-uncommon-cause-of-chronic-abdominal-pain.html
Sclerosing mesenteritis (SM), also known as mesenteric panniculitis or mesenteric lipodystrophy, is a rare disease that affects the mesentery of the small intestine. […] Asymptomatic patients typically require no treatment, while refractory cases have shown some symptomatic improvement with immunosuppressive therapy. […] Due to the rarity of the condition, there are no specific guidelines for treatment of SM however steroids, colchicine, azathioprine, thalidomide, cyclophosphamide and progesterone have been tried, however asymptomatic cases don’t need therapy. Surgical resection is recommended for non-resolving cases and complicated by bowel obstruction. […] A treatment algorithm was prepared by Akram after review on 92 cases. Asymptomatic patients with incidental diagnosis do not need treatment. Patients with features of bowel obstruction need to undergo surgical treatment followed by tamoxifen plus tapering dose of steroids if there is persistence of symptoms.
- #29 Sclerosing Mesenteritis Managed Conservatively With Prednisonehttps://pmc.ncbi.nlm.nih.gov/articles/PMC10040226/
The authors present the case of a middle-aged lady with two weeks of abdominal pain. […] In our patients case, she was able to be managed conservatively, without the need for surgery. This reflects the most benign and self-limiting natural history of the disease. […] Treatment for sclerosing mesenteritis typically involves medications to manage symptoms and reduce inflammation. These can include non-steroidal anti-inflammatory drugs (NSAIDs) and immunosuppressive agents. Surgery is reserved for bowel obstruction or perforation or complicated panniculitis refractory to medical treatment. […] In many cases, where the condition is not severe, conservative treatment with observation would suffice. This was the case with our patient. A similar resolution of sclerosing mesenteritis with steroid therapy is documented in the literature. […] Our patient had a relatively benign course which did not require surgical intervention but rather was able to be managed with only steroid therapy.
- #30 Sclerosing Mesenteritis Presenting with Small Bowel Obstruction in a Patient with Compensated Cirrhosis: A Case Reporthttps://fortuneonline.org/articles/sclerosing-mesenteritis-presenting-with-small-bowel-obstruction-in-a-patient-with-compensated-cirrhosis-a-case-report.html
Sclerosing Mesenteritis (SM) is a rare fibroinflammatory disease of unknown etiology in which intestinal obstruction results from encasement of variable lengths of bowel by a dense fibrocollagenous membrane that gives the appearance of a cocoon. […] The insidious onset of bowel obstruction symptoms in patients with even compensated cirrhosis, should include SM in the differential diagnosis. […] Diagnosis of SM is a diagnostic challenge and requires a high index of clinical suspicion. It can be facilitated by the patients history, existing predisposing factors, various biochemical parameters and radiological imaging. […] A better awareness of this rare clinical entity and the imaging findings may facilitate pre-operative diagnosis, which is critical for selecting the appropriate surgical intervention or even avoid the need for surgery and instead apply immunosuppressive drug therapy. […] Our case suggests that the insidious onset of bowel obstruction symptoms in a cirrhotic patient, even if cirrhosis is compensated and uncomplicated, should include SM in the differential diagnosis.
- #31https://www.alliedacademies.org/articles/igg4related-sclerosing-mesenteritis-and-its-possible-relation-to-papillarythyroid-carcinoma-in-a-27yearold-egyptian-woman-8629.html
Sclerosing mesenteritis (SM) is a rare fibro inflammatory disease unknown etiology involves the small bowel mesentry, most frequently observed in middle aged and older men. […] Management ranges from left untreated in asymptomatic patients to surgical exploration in life threatening complications as bowel obstruction or perforation or if there is a suspicion of malignancy. Medical treatment including corticosteroids, tamoxifen, cyclophosphamide and azathioprine has also shown good results especially corticosteroids if SM is due to IgG4- RD. […] Building on the specific treatment recommendations given to patients by their doctor, meetings between the care manager and the patient could take a broad perspective and consider the medical, social, behavioral, and emotional impact that living with a chronic conditioner reducing a health risk might have on the patients quality of life.
- #32https://www.alliedacademies.org/articles/igg4related-sclerosing-mesenteritis-and-its-possible-relation-to-papillarythyroid-carcinoma-in-a-27yearold-egyptian-woman-8629.html
Each of the care managers interventions was intended to increase patient empowerment, supporting patients to develop the confidence to effectively self-manage their health. […] Unfortunately, in this case like many others we dont have this system of care manager, social workers, actually, her husband which is a police officer did well the role of care manager. […] We recommend inclusion of IgG related sclerosis mesenteritis in every case of IgG4 recurrent abdominal pain and/or mesenteric masses. […] IgG4-RD may be associated with SM, Hashimotos thyroiditis, and papillary thyroid carcinoma. Although SM may be difficult to be diagnosed without histopathology, yet, it should be considered in any abdominal pain or mesentric mass to avoid unnecessary surgical interventions especially with good response to corticosteroids.
- #33https://www.alliedacademies.org/articles/igg4related-sclerosing-mesenteritis-and-its-possible-relation-to-papillarythyroid-carcinoma-in-a-27yearold-egyptian-woman-8629.html
Each of the care managers interventions was intended to increase patient empowerment, supporting patients to develop the confidence to effectively self-manage their health. […] Unfortunately, in this case like many others we dont have this system of care manager, social workers, actually, her husband which is a police officer did well the role of care manager. […] We recommend inclusion of IgG related sclerosis mesenteritis in every case of IgG4 recurrent abdominal pain and/or mesenteric masses. […] IgG4-RD may be associated with SM, Hashimotos thyroiditis, and papillary thyroid carcinoma. Although SM may be difficult to be diagnosed without histopathology, yet, it should be considered in any abdominal pain or mesentric mass to avoid unnecessary surgical interventions especially with good response to corticosteroids.
- #34https://www.alliedacademies.org/articles/igg4related-sclerosing-mesenteritis-and-its-possible-relation-to-papillarythyroid-carcinoma-in-a-27yearold-egyptian-woman-8629.html
Each of the care managers interventions was intended to increase patient empowerment, supporting patients to develop the confidence to effectively self-manage their health. […] Unfortunately, in this case like many others we dont have this system of care manager, social workers, actually, her husband which is a police officer did well the role of care manager. […] We recommend inclusion of IgG related sclerosis mesenteritis in every case of IgG4 recurrent abdominal pain and/or mesenteric masses. […] IgG4-RD may be associated with SM, Hashimotos thyroiditis, and papillary thyroid carcinoma. Although SM may be difficult to be diagnosed without histopathology, yet, it should be considered in any abdominal pain or mesentric mass to avoid unnecessary surgical interventions especially with good response to corticosteroids.
- #35 Mayo Clinic Proceedings Sclerosing Mesenteritis: A Concise Clinical Review for Clinicians (May 1, 2024) | Mayo Clinic School of Continuous Professional Developmenthttps://ce.mayo.edu/internal-medicine/content/mayo-clinic-proceedings-sclerosing-mesenteritis-concise-clinical-review-clinicians-may-1
On completion of this article, you should be able to (1) identify risk factors for sclerosing mesenteritis (SM); (2) recognize common clinical symptoms of SM and formulate a differential diagnosis for clinically incongruent cases; and (3) develop a treatment plan for patients with SM based on the severity of symptoms, comorbidities, and/or complications. […] Successful completion of this CME activity enables the participant to earn up to 1 Medical Knowledge MOC point in the American Board of Internal Medicineâs (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. […] A certificate of attendance will be provided to other healthcare professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations.
- #36https://www.alliedacademies.org/articles/igg4related-sclerosing-mesenteritis-and-its-possible-relation-to-papillarythyroid-carcinoma-in-a-27yearold-egyptian-woman-8629.html
Sclerosing mesenteritis (SM) is a rare fibro inflammatory disease unknown etiology involves the small bowel mesentry, most frequently observed in middle aged and older men. […] Management ranges from left untreated in asymptomatic patients to surgical exploration in life threatening complications as bowel obstruction or perforation or if there is a suspicion of malignancy. Medical treatment including corticosteroids, tamoxifen, cyclophosphamide and azathioprine has also shown good results especially corticosteroids if SM is due to IgG4- RD. […] Building on the specific treatment recommendations given to patients by their doctor, meetings between the care manager and the patient could take a broad perspective and consider the medical, social, behavioral, and emotional impact that living with a chronic conditioner reducing a health risk might have on the patients quality of life.
- #37https://www.alliedacademies.org/articles/igg4related-sclerosing-mesenteritis-and-its-possible-relation-to-papillarythyroid-carcinoma-in-a-27yearold-egyptian-woman-8629.html
Sclerosing mesenteritis (SM) is a rare fibro inflammatory disease unknown etiology involves the small bowel mesentry, most frequently observed in middle aged and older men. […] Management ranges from left untreated in asymptomatic patients to surgical exploration in life threatening complications as bowel obstruction or perforation or if there is a suspicion of malignancy. Medical treatment including corticosteroids, tamoxifen, cyclophosphamide and azathioprine has also shown good results especially corticosteroids if SM is due to IgG4- RD. […] Building on the specific treatment recommendations given to patients by their doctor, meetings between the care manager and the patient could take a broad perspective and consider the medical, social, behavioral, and emotional impact that living with a chronic conditioner reducing a health risk might have on the patients quality of life.
- #38https://www.alliedacademies.org/articles/igg4related-sclerosing-mesenteritis-and-its-possible-relation-to-papillarythyroid-carcinoma-in-a-27yearold-egyptian-woman-8629.html
Each of the care managers interventions was intended to increase patient empowerment, supporting patients to develop the confidence to effectively self-manage their health. […] Unfortunately, in this case like many others we dont have this system of care manager, social workers, actually, her husband which is a police officer did well the role of care manager. […] We recommend inclusion of IgG related sclerosis mesenteritis in every case of IgG4 recurrent abdominal pain and/or mesenteric masses. […] IgG4-RD may be associated with SM, Hashimotos thyroiditis, and papillary thyroid carcinoma. Although SM may be difficult to be diagnosed without histopathology, yet, it should be considered in any abdominal pain or mesentric mass to avoid unnecessary surgical interventions especially with good response to corticosteroids.
- #39https://www.alliedacademies.org/articles/igg4related-sclerosing-mesenteritis-and-its-possible-relation-to-papillarythyroid-carcinoma-in-a-27yearold-egyptian-woman-8629.html
Each of the care managers interventions was intended to increase patient empowerment, supporting patients to develop the confidence to effectively self-manage their health. […] Unfortunately, in this case like many others we dont have this system of care manager, social workers, actually, her husband which is a police officer did well the role of care manager. […] We recommend inclusion of IgG related sclerosis mesenteritis in every case of IgG4 recurrent abdominal pain and/or mesenteric masses. […] IgG4-RD may be associated with SM, Hashimotos thyroiditis, and papillary thyroid carcinoma. Although SM may be difficult to be diagnosed without histopathology, yet, it should be considered in any abdominal pain or mesentric mass to avoid unnecessary surgical interventions especially with good response to corticosteroids.
- #40 Sclerosing Mesenteritis Presenting with Small Bowel Obstruction in a Patient with Compensated Cirrhosis: A Case Reporthttps://fortuneonline.org/articles/sclerosing-mesenteritis-presenting-with-small-bowel-obstruction-in-a-patient-with-compensated-cirrhosis-a-case-report.html
Sclerosing Mesenteritis (SM) is a rare fibroinflammatory disease of unknown etiology in which intestinal obstruction results from encasement of variable lengths of bowel by a dense fibrocollagenous membrane that gives the appearance of a cocoon. […] The insidious onset of bowel obstruction symptoms in patients with even compensated cirrhosis, should include SM in the differential diagnosis. […] Diagnosis of SM is a diagnostic challenge and requires a high index of clinical suspicion. It can be facilitated by the patients history, existing predisposing factors, various biochemical parameters and radiological imaging. […] A better awareness of this rare clinical entity and the imaging findings may facilitate pre-operative diagnosis, which is critical for selecting the appropriate surgical intervention or even avoid the need for surgery and instead apply immunosuppressive drug therapy. […] Our case suggests that the insidious onset of bowel obstruction symptoms in a cirrhotic patient, even if cirrhosis is compensated and uncomplicated, should include SM in the differential diagnosis.
- #41 Idiopathic sclerosing mesenteritis presenting with small bowel volvulus in a patient with antiphospholipid syndrome: A case reporthttps://www.wjgnet.com/2307-8960/full/v11/i14/3304.htm
Sclerosing mesenteritis is a rare disorder involving inflammation of the mesentery. Its etiology remains unclear, but it is believed to be associated with previous abdominal surgery, trauma, autoimmune disorders, infection, or malignancy. Clinical manifestations of sclerosing mesenteritis are varied and include chronic abdominal pain, bloating, diarrhea, weight loss, formation of an intra-abdominal mass, bowel obstruction, and chylous ascites. […] Sclerosing mesenteritis is a rare condition, and patients with no clear etiology should be considered for treatment with immunosuppressive therapy. […] In patients with sclerosing mesenteritis, any condition that causes chronic inflammation of mesenteric tissue should be investigated. Antiphospholipid syndrome may be linked with chronic thrombotic activity that can contribute to chronic ischemia of the mesentery. Patients with uncertain etiology should be considered for treatment with immunosuppressive therapy.
- #42 Idiopathic sclerosing mesenteritis presenting with small bowel volvulus in a patient with antiphospholipid syndrome: A case reporthttps://www.wjgnet.com/2307-8960/full/v11/i14/3304.htm
Sclerosing mesenteritis is a chronic inflammation of the mesentery that is commonly caused by other medical conditions, including infection, autoimmune conditions, and malignancy. Symptomatic patients with unclear etiology should be considered for treatment with immunosuppressive medications. In addition, while rare, chronic thrombotic conditions can also cause sclerosing mesenteritis, and they should also be considered.
- #43 Sclerosing Mesenteritis Presenting with Small Bowel Obstruction in a Patient with Compensated Cirrhosis: A Case Reporthttps://fortuneonline.org/articles/sclerosing-mesenteritis-presenting-with-small-bowel-obstruction-in-a-patient-with-compensated-cirrhosis-a-case-report.html
Sclerosing Mesenteritis (SM) is a rare fibroinflammatory disease of unknown etiology in which intestinal obstruction results from encasement of variable lengths of bowel by a dense fibrocollagenous membrane that gives the appearance of a cocoon. […] The insidious onset of bowel obstruction symptoms in patients with even compensated cirrhosis, should include SM in the differential diagnosis. […] Diagnosis of SM is a diagnostic challenge and requires a high index of clinical suspicion. It can be facilitated by the patients history, existing predisposing factors, various biochemical parameters and radiological imaging. […] A better awareness of this rare clinical entity and the imaging findings may facilitate pre-operative diagnosis, which is critical for selecting the appropriate surgical intervention or even avoid the need for surgery and instead apply immunosuppressive drug therapy. […] Our case suggests that the insidious onset of bowel obstruction symptoms in a cirrhotic patient, even if cirrhosis is compensated and uncomplicated, should include SM in the differential diagnosis.
- #44 Sclerosing Mesenteritis Presenting with Small Bowel Obstruction in a Patient with Compensated Cirrhosis: A Case Reporthttps://fortuneonline.org/articles/sclerosing-mesenteritis-presenting-with-small-bowel-obstruction-in-a-patient-with-compensated-cirrhosis-a-case-report.html
Sclerosing Mesenteritis (SM) is a rare fibroinflammatory disease of unknown etiology in which intestinal obstruction results from encasement of variable lengths of bowel by a dense fibrocollagenous membrane that gives the appearance of a cocoon. […] The insidious onset of bowel obstruction symptoms in patients with even compensated cirrhosis, should include SM in the differential diagnosis. […] Diagnosis of SM is a diagnostic challenge and requires a high index of clinical suspicion. It can be facilitated by the patients history, existing predisposing factors, various biochemical parameters and radiological imaging. […] A better awareness of this rare clinical entity and the imaging findings may facilitate pre-operative diagnosis, which is critical for selecting the appropriate surgical intervention or even avoid the need for surgery and instead apply immunosuppressive drug therapy. […] Our case suggests that the insidious onset of bowel obstruction symptoms in a cirrhotic patient, even if cirrhosis is compensated and uncomplicated, should include SM in the differential diagnosis.
- #45 Sclerosing Mesenteritis Presenting with Small Bowel Obstruction in a Patient with Compensated Cirrhosis: A Case Reporthttps://fortuneonline.org/articles/sclerosing-mesenteritis-presenting-with-small-bowel-obstruction-in-a-patient-with-compensated-cirrhosis-a-case-report.html
Sclerosing Mesenteritis (SM) is a rare fibroinflammatory disease of unknown etiology in which intestinal obstruction results from encasement of variable lengths of bowel by a dense fibrocollagenous membrane that gives the appearance of a cocoon. […] The insidious onset of bowel obstruction symptoms in patients with even compensated cirrhosis, should include SM in the differential diagnosis. […] Diagnosis of SM is a diagnostic challenge and requires a high index of clinical suspicion. It can be facilitated by the patients history, existing predisposing factors, various biochemical parameters and radiological imaging. […] A better awareness of this rare clinical entity and the imaging findings may facilitate pre-operative diagnosis, which is critical for selecting the appropriate surgical intervention or even avoid the need for surgery and instead apply immunosuppressive drug therapy. […] Our case suggests that the insidious onset of bowel obstruction symptoms in a cirrhotic patient, even if cirrhosis is compensated and uncomplicated, should include SM in the differential diagnosis.
- #46 Sclerosing mesenteritis:an uncommon cause of chronic abdominal pain – MedCrave onlinehttps://medcraveonline.com/GHOA/sclerosing-mesenteritisan-uncommon-cause-of-chronic-abdominal-pain.html
Sclerosing mesenteritis (SM), also known as mesenteric panniculitis or mesenteric lipodystrophy, is a rare disease that affects the mesentery of the small intestine. […] Asymptomatic patients typically require no treatment, while refractory cases have shown some symptomatic improvement with immunosuppressive therapy. […] Due to the rarity of the condition, there are no specific guidelines for treatment of SM however steroids, colchicine, azathioprine, thalidomide, cyclophosphamide and progesterone have been tried, however asymptomatic cases don’t need therapy. Surgical resection is recommended for non-resolving cases and complicated by bowel obstruction. […] A treatment algorithm was prepared by Akram after review on 92 cases. Asymptomatic patients with incidental diagnosis do not need treatment. Patients with features of bowel obstruction need to undergo surgical treatment followed by tamoxifen plus tapering dose of steroids if there is persistence of symptoms.
- #47 Sclerosing mesenteritis:an uncommon cause of chronic abdominal pain – MedCrave onlinehttps://medcraveonline.com/GHOA/sclerosing-mesenteritisan-uncommon-cause-of-chronic-abdominal-pain.html
Our patient had surgery for repair of the hernia but not all the affected mesenteries were removed. Several months after the diagnosis, he had a comfortable life with on and off mild abdominal pain which was resolved by ibuprofen. […] Finally, SM is a rare cause of chronic abdominal pain. Though most of the cases are benign like ours, they can be associated with underlying malignancy which need to be ruled out. There are no specific guidelines for treatment of SM till date. Further studies are required to formulate specific guidelines for the treatment of SM for which our case could add value.
- #48 Mayo Clinic Proceedings Sclerosing Mesenteritis: A Concise Clinical Review for Clinicians (May 1, 2024) | Mayo Clinic School of Continuous Professional Developmenthttps://ce.mayo.edu/internal-medicine/content/mayo-clinic-proceedings-sclerosing-mesenteritis-concise-clinical-review-clinicians-may-1
On completion of this article, you should be able to (1) identify risk factors for sclerosing mesenteritis (SM); (2) recognize common clinical symptoms of SM and formulate a differential diagnosis for clinically incongruent cases; and (3) develop a treatment plan for patients with SM based on the severity of symptoms, comorbidities, and/or complications. […] Successful completion of this CME activity enables the participant to earn up to 1 Medical Knowledge MOC point in the American Board of Internal Medicineâs (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. […] A certificate of attendance will be provided to other healthcare professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations.
- #49 Mayo Clinic Proceedings Sclerosing Mesenteritis: A Concise Clinical Review for Clinicians (May 1, 2024) | Mayo Clinic School of Continuous Professional Developmenthttps://ce.mayo.edu/internal-medicine/content/mayo-clinic-proceedings-sclerosing-mesenteritis-concise-clinical-review-clinicians-may-1
On completion of this article, you should be able to (1) identify risk factors for sclerosing mesenteritis (SM); (2) recognize common clinical symptoms of SM and formulate a differential diagnosis for clinically incongruent cases; and (3) develop a treatment plan for patients with SM based on the severity of symptoms, comorbidities, and/or complications. […] Successful completion of this CME activity enables the participant to earn up to 1 Medical Knowledge MOC point in the American Board of Internal Medicineâs (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. […] A certificate of attendance will be provided to other healthcare professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations.
- #50 Mayo Clinic Proceedings Sclerosing Mesenteritis: A Concise Clinical Review for Clinicians (May 1, 2024) | Mayo Clinic School of Continuous Professional Developmenthttps://ce.mayo.edu/internal-medicine/content/mayo-clinic-proceedings-sclerosing-mesenteritis-concise-clinical-review-clinicians-may-1
On completion of this article, you should be able to (1) identify risk factors for sclerosing mesenteritis (SM); (2) recognize common clinical symptoms of SM and formulate a differential diagnosis for clinically incongruent cases; and (3) develop a treatment plan for patients with SM based on the severity of symptoms, comorbidities, and/or complications. […] Successful completion of this CME activity enables the participant to earn up to 1 Medical Knowledge MOC point in the American Board of Internal Medicineâs (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. […] A certificate of attendance will be provided to other healthcare professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations.
- #51 Mayo Clinic Proceedings Sclerosing Mesenteritis: A Concise Clinical Review for Clinicians (May 1, 2024) | Mayo Clinic School of Continuous Professional Developmenthttps://ce.mayo.edu/internal-medicine/content/mayo-clinic-proceedings-sclerosing-mesenteritis-concise-clinical-review-clinicians-may-1
On completion of this article, you should be able to (1) identify risk factors for sclerosing mesenteritis (SM); (2) recognize common clinical symptoms of SM and formulate a differential diagnosis for clinically incongruent cases; and (3) develop a treatment plan for patients with SM based on the severity of symptoms, comorbidities, and/or complications. […] Successful completion of this CME activity enables the participant to earn up to 1 Medical Knowledge MOC point in the American Board of Internal Medicineâs (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. […] A certificate of attendance will be provided to other healthcare professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations.
- #52 Sclerosing mesenteritis – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/sclerosing-mesenteritis/diagnosis-treatment/drc-20450343
Our caring team of Mayo Clinic experts can help you with your sclerosing mesenteritis-related health concerns […] If you are not experiencing discomfort from sclerosing mesenteritis, you may not need treatment. Instead, occasional imaging tests may be recommended to monitor your condition. […] If you begin to experience symptoms of sclerosing mesenteritis, you may choose to begin treatment. […] You may need surgery if the scar tissue blocks food from moving through your digestive tract.
- #53 Sclerosing Mesenteritis Managed Conservatively With Prednisonehttps://pmc.ncbi.nlm.nih.gov/articles/PMC10040226/
The authors present the case of a middle-aged lady with two weeks of abdominal pain. […] In our patients case, she was able to be managed conservatively, without the need for surgery. This reflects the most benign and self-limiting natural history of the disease. […] Treatment for sclerosing mesenteritis typically involves medications to manage symptoms and reduce inflammation. These can include non-steroidal anti-inflammatory drugs (NSAIDs) and immunosuppressive agents. Surgery is reserved for bowel obstruction or perforation or complicated panniculitis refractory to medical treatment. […] In many cases, where the condition is not severe, conservative treatment with observation would suffice. This was the case with our patient. A similar resolution of sclerosing mesenteritis with steroid therapy is documented in the literature. […] Our patient had a relatively benign course which did not require surgical intervention but rather was able to be managed with only steroid therapy.
- #54https://www.alliedacademies.org/articles/igg4related-sclerosing-mesenteritis-and-its-possible-relation-to-papillarythyroid-carcinoma-in-a-27yearold-egyptian-woman-8629.html
Each of the care managers interventions was intended to increase patient empowerment, supporting patients to develop the confidence to effectively self-manage their health. […] Unfortunately, in this case like many others we dont have this system of care manager, social workers, actually, her husband which is a police officer did well the role of care manager. […] We recommend inclusion of IgG related sclerosis mesenteritis in every case of IgG4 recurrent abdominal pain and/or mesenteric masses. […] IgG4-RD may be associated with SM, Hashimotos thyroiditis, and papillary thyroid carcinoma. Although SM may be difficult to be diagnosed without histopathology, yet, it should be considered in any abdominal pain or mesentric mass to avoid unnecessary surgical interventions especially with good response to corticosteroids.