Materiały źródłowe

• #1 Anaphylaxis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK482124/

  Anaphylaxis is an acute, life-threatening hypersensitivity disorder defined as a generalized, rapidly evolving, multi-systemic allergic reaction. […] Common inciting sources may include exposure to certain medications, foods, or insect stings. […] The most common causes include bee stings, fire ant bites, latex, and foods (peanuts, tree nuts, fish, shellfish, milk, eggs, wheat, spelt, rye, barley, soy, red meat, and sesame). […] Rapid mast cell and basophil degranulation are attributed to the causation of the overactive immune response that culminates in the clinical picture of anaphylaxis. […] Anaphylaxis is a rapid systemic and unpredictable disorder that is life-threatening. The disorder often occurs after exposure to certain antigens, mostly insect venom, food, or medications. The condition is immune-mediated and rapidly induces symptoms.

• #2 Differential diagnosis of anaphylaxis in adults and children – UpToDate

  https://www.uptodate.com/contents/differential-diagnosis-of-anaphylaxis-in-adults-and-children

  Anaphylaxis is an acute, potentially life-threatening multisystem syndrome caused by the sudden release of mast cell mediators into the systemic circulation. It most often results from immunoglobulin (Ig)E-mediated reactions to foods, drugs, and insect stings, but any agent capable of producing a sudden, systemic degranulation of mast cells can produce it. […] The diagnosis can be challenging, and clinical criteria may be helpful in recognizing anaphylaxis. […] Anaphylaxis recognition may be straightforward in patients with a clear history of exposure to a known or likely allergen in the time immediately preceding onset of characteristic symptoms in several body systems. […] However, the signs and symptoms of anaphylaxis overlap with those of many other disorders, and the diagnosis can be quite difficult to make with certainty in some situations. […] Common disorders that mimic anaphylaxis include acute generalized urticaria, acute angioedema, acute asthma exacerbations, syncope (faint), and panic attacks or acute anxiety. […] Urticaria can be associated with allergen exposure as well as infections or physical stimuli, such as heat and cold.

• #3 Anaphylaxis: symptoms, causes and diagnosis – The Pharmaceutical Journal

  https://pharmaceutical-journal.com/article/ld/anaphylaxis-symptoms-causes-and-diagnosis

  Anaphylaxis is a life-threatening, generalised or systemic hypersensitivity reaction, involving the release of mediators from mast cells, basophils and recruited inflammatory cells, and is characterised by rapidly developing life-threatening airway and/or circulation problems with associated skin and mucosal changes. […] Often the result of an allergic response that can be immunologically mediated, non-immunologically mediated or idiopathic, it is estimated that around 1 in 1,333 people in England has experienced anaphylaxis at some point in their lives. […] There are a range of causes of anaphylaxis, which can be grouped together. […] If a cause or trigger cannot be identified, it is described as idiopathic anaphylaxis. […] Between one-third and half of anaphylaxis cases that present to emergency departments are caused by foods, with the highest incidence of these cases occurring in young children.

• #4 Anaphylaxis | Causes, Symptoms & Treatment | ACAAI Public Website

  https://acaai.org/allergies/symptoms/anaphylaxis/

  Anaphylaxis is a rare but severe allergic reaction. It can occur suddenly, can worsen quickly and can be deadly. […] This severe reaction happens when an over-release of chemicals puts the person into shock. Allergies to food, insect stings, medications and latex are most frequently associated with anaphylaxis. […] If you have a history of allergies and/or asthma and have previously had a severe reaction, you are at greater risk for anaphylaxis. […] The most common triggers are: Food: including peanuts, tree nuts such as cashews and pistachio, fish, shellfish, cow’s milk, eggs and sesame. […] Latex: found in disposable gloves, intravenous tubes, syringes, adhesive tapes and catheters. […] Medication: including penicillin and other antibiotics, aspirin and non-steroidal anti-inflammatory drugs such as ibuprofen, and medications used for anesthesia. […] Insect sting: with bees, wasps, hornets, yellow jackets and fire ants being the most likely to trigger anaphylaxis.

• #5 Anaphylaxis: symptoms, causes and diagnosis – The Pharmaceutical Journal

  https://pharmaceutical-journal.com/article/ld/anaphylaxis-symptoms-causes-and-diagnosis

  Anaphylaxis is a life-threatening, generalised or systemic hypersensitivity reaction, involving the release of mediators from mast cells, basophils and recruited inflammatory cells, and is characterised by rapidly developing life-threatening airway and/or circulation problems with associated skin and mucosal changes. […] Often the result of an allergic response that can be immunologically mediated, non-immunologically mediated or idiopathic, it is estimated that around 1 in 1,333 people in England has experienced anaphylaxis at some point in their lives. […] There are a range of causes of anaphylaxis, which can be grouped together. […] If a cause or trigger cannot be identified, it is described as idiopathic anaphylaxis. […] Between one-third and half of anaphylaxis cases that present to emergency departments are caused by foods, with the highest incidence of these cases occurring in young children.

• #6 Anaphylaxis Statistics – Allergy & Asthma Network

  https://allergyasthmanetwork.org/anaphylaxis/anaphylaxis-statistics/

  Anaphylaxis is caused by exposure to a trigger or allergen. The most common triggers include: […] In infants, food accounts for 73% of anaphylaxis symptoms. The most common trigger foods are egg, milk, peanut, and banana. Drugs account for 20% of anaphylaxis cases in infants, followed by unknown triggers. […] The fatality rate for an anaphylactic reaction in the United States is about 0.3%.

• #7 Allergies – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/allergies/symptoms-causes/syc-20351497

  Some types of allergies can trigger a severe reaction known as anaphylaxis. Certain foods, insect stings and medicines are among the allergens that can set off this life-threatening emergency. Anaphylaxis can cause you to go into shock. Other symptoms include: […] Anaphylaxis. If you have severe allergies, that raises your risk of this serious allergic reaction. Foods, medicines, latex and insect stings are the most common triggers of anaphylaxis. […] Various substances can cause allergies. An allergy starts when the immune system mistakes a substance that’s usually harmless for a dangerous invader. The immune system then makes antibodies that stay on the alert for that specific allergen. When you’re exposed to the allergen again, these antibodies can release some immune system chemicals that cause allergy symptoms.

• #8 Anaphylaxis: Causes, Symptoms and Treatment | Allergy Insider

  https://www.thermofisher.com/allergy/us/en/living-with-allergies/symptom-management/anaphylaxis.html

  Anaphylaxis is a severe and potentially life-threatening allergic reaction. Like other allergy symptoms, its triggered when the immune system overreacts and releases histamine (among other chemicals) in response to an allergen, such as peanuts, shellfish, latex, insect venom, dust mites, and countless more. […] While there may be other causes of anaphylaxis, such as exercise, allergens are the main culprits. Among them, food allergens are the most frequent triggers of anaphylaxis in children, and insect venom and various drug allergies are the most prevalent offenders in adults. Additionally, according to an article published in The Journal of Allergy and Clinical Immunology, drugs are the most common reported cause of fatal anaphylaxis in countries such as Australia, New Zealand, the United Kingdom, Brazil, and the United States.

• #9 Anaphylaxis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/135065-overview

  IgE-mediated anaphylaxis is the classic form of anaphylaxis, whereby a sensitizing antigen elicits an IgE antibody response in a susceptible individual. The antigen-specific IgE antibodies then bind to mast cells and basophils. Subsequent exposure to the sensitizing antigen causes cross-linking of cell-bound IgE, resulting in mast cell (and/or basophil) degranulation. […] Other types of immunologic anaphylaxis do not involve IgE. For example, anaphylaxis resulting from administration of blood products, including intravenous immunoglobulin, or animal antiserum is due, at least in part, to complement activation. Immune complexes formed in vivo or in vitro can activate the complement cascade. Certain byproducts of the cascade—plasma-activated complement 3 (C3a), plasma-activated complement 4 (C4a), and plasma-activated complement 5 (C5a)—are called anaphylatoxins and can cause mast cell/basophil degranulation.

• #10 What is Anaphylaxis? Causes, Symptoms, Treatments & More | CAAC

  https://www.carolinaasthma.com/blog/what-is-anaphylaxis/

  Most have heard of allergic reactions, but few understand the characteristics of the most serious and life-threatening allergic reaction known as anaphylaxis. […] Anaphylaxis, as well as allergies in general, occurs when the body overreacts to an allergen. […] When the body is exposed to an allergen, it responds by producing histamine and other chemicals causing your blood vessels to dilate. This allows more fluid to enter your tissues and causes swelling. During anaphylaxis, these chemicals are released throughout the whole body and can cause low blood pressure, hives, and difficulty breathing. […] Food allergies are the most common cause of anaphylaxis. Some prevalent triggers include: shellfish, nuts, milk, eggs, fish, and some fruits. […] Insect stings, especially those from bees or wasps, can also trigger anaphylaxis.

• #11 Anaphylaxis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/135065-overview

  IgE-mediated anaphylaxis is the classic form of anaphylaxis, whereby a sensitizing antigen elicits an IgE antibody response in a susceptible individual. The antigen-specific IgE antibodies then bind to mast cells and basophils. Subsequent exposure to the sensitizing antigen causes cross-linking of cell-bound IgE, resulting in mast cell (and/or basophil) degranulation. […] Other types of immunologic anaphylaxis do not involve IgE. For example, anaphylaxis resulting from administration of blood products, including intravenous immunoglobulin, or animal antiserum is due, at least in part, to complement activation. Immune complexes formed in vivo or in vitro can activate the complement cascade. Certain byproducts of the cascade—plasma-activated complement 3 (C3a), plasma-activated complement 4 (C4a), and plasma-activated complement 5 (C5a)—are called anaphylatoxins and can cause mast cell/basophil degranulation.

• #12 Anaphylaxis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/135065-overview

  Certain agents are thought to cause direct nonimmunologic release of mediators from mast cells, a process not mediated by IgE. These include opioids, dextrans, protamine, and vancomycin. Mechanisms underlying these reactions are poorly understood but may involve specific receptors (eg, opioids) or nonreceptor-mediated mast cell activation (eg, hyperosmolarity). […] The most common inciting agents in anaphylaxis are foods, Hymenoptera stings, and intravenous (IV) contrast materials. Anaphylaxis may also be idiopathic. […] Typical examples of IgE-mediated anaphylaxis include the reactions to many foods, drugs, and insect stings. […] Hypersensitivity to foods is a problem encountered throughout the industrialized world. […] In the United States, an estimated 4 million Americans have well-substantiated food allergies.

• #13 Anaphylaxis | Causes, Symptoms & Treatment | ACAAI Public Website

  https://acaai.org/allergies/symptoms/anaphylaxis/

  Anaphylaxis is a rare but severe allergic reaction. It can occur suddenly, can worsen quickly and can be deadly. […] This severe reaction happens when an over-release of chemicals puts the person into shock. Allergies to food, insect stings, medications and latex are most frequently associated with anaphylaxis. […] If you have a history of allergies and/or asthma and have previously had a severe reaction, you are at greater risk for anaphylaxis. […] The most common triggers are: Food: including peanuts, tree nuts such as cashews and pistachio, fish, shellfish, cow’s milk, eggs and sesame. […] Latex: found in disposable gloves, intravenous tubes, syringes, adhesive tapes and catheters. […] Medication: including penicillin and other antibiotics, aspirin and non-steroidal anti-inflammatory drugs such as ibuprofen, and medications used for anesthesia. […] Insect sting: with bees, wasps, hornets, yellow jackets and fire ants being the most likely to trigger anaphylaxis.

• #14 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  Anaphylaxis is a severe allergic reaction. […] Food allergies are one of the main causes of anaphylaxis. Other causes include stinging insects, medications and latex. […] Anaphylaxis usually begins with skin symptoms of hives or itching. […] What causes anaphylaxis? […] Food allergies are one of the main causes of anaphylaxis. Foods that can cause this severe anaphylactic reaction include: Cows milk, Eggs, Peanuts, Shellfish (shrimp and lobster), Soy, Tree nuts (like walnuts, hazelnuts, Brazil nuts and cashews), Wheat, Seeds (like sesame seeds and sunflower seeds). […] Other allergens (substances that cause allergies) that can lead to anaphylaxis include: Certain medications and substances, including penicillin, nonsteroidal anti-inflammatory drugs (NSAIDs) and dye used for CT scans. Latex, found in items such as disposable gloves, catheters and adhesive tapes. Insect stings from bees, wasps, hornets and yellow jackets.

• #15 Anaphylaxis – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/anaphylaxis/symptoms-causes/syc-20351468

  Anaphylaxis causes the immune system to release a flood of chemicals that can cause you to go into shock blood pressure drops suddenly and the airways narrow, blocking breathing. […] Allergy symptoms aren’t usually life-threatening, but a severe allergic reaction can lead to anaphylaxis. […] The most common anaphylaxis triggers in children are food allergies, such as to peanuts and tree nuts, fish, shellfish, wheat, soy, sesame and milk. […] Besides allergy to peanuts, nuts, fish, sesame and shellfish, anaphylaxis triggers in adults include: […] Although not common, some people develop anaphylaxis from aerobic exercise, such as jogging, or even less intense physical activity, such as walking. […] If you don’t know what triggers an allergy attack, certain tests can help identify the allergen. In some cases, the cause of anaphylaxis is not identified (idiopathic anaphylaxis).

• #16 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  Anaphylaxis is a severe allergic reaction. […] Food allergies are one of the main causes of anaphylaxis. Other causes include stinging insects, medications and latex. […] Anaphylaxis usually begins with skin symptoms of hives or itching. […] What causes anaphylaxis? […] Food allergies are one of the main causes of anaphylaxis. Foods that can cause this severe anaphylactic reaction include: Cows milk, Eggs, Peanuts, Shellfish (shrimp and lobster), Soy, Tree nuts (like walnuts, hazelnuts, Brazil nuts and cashews), Wheat, Seeds (like sesame seeds and sunflower seeds). […] Other allergens (substances that cause allergies) that can lead to anaphylaxis include: Certain medications and substances, including penicillin, nonsteroidal anti-inflammatory drugs (NSAIDs) and dye used for CT scans. Latex, found in items such as disposable gloves, catheters and adhesive tapes. Insect stings from bees, wasps, hornets and yellow jackets.

• #17 Anaphylaxis (Anaphylactic Reaction): Symptoms, Causes, Treatment

  https://www.webmd.com/allergies/anaphylaxis

  Anaphylaxis happens when you have an antibody, something that usually fights infection, that reacts too much to something that should be harmless, like food. It might not happen the first time you come in contact with the trigger, but it can get worse over time. […] In children, the most common cause of anaphylaxis is food. For adults, medications more often cause it. […] Common food triggers for children are: Peanuts, Shellfish, Fish, Milk, Eggs, Soy, Wheat. […] Common food triggers for adults are: Shellfish, Tree nuts (walnuts, hazelnuts, cashews, pistachios, pine nuts, and almonds), Peanuts. […] Common medication triggers are: Penicillin (more often following a shot rather than a pill), Muscle relaxants like the ones used for anesthesia, Aspirin, ibuprofen, and other NSAIDs (nonsteroidal anti-inflammatory drugs), Anti-seizure medications.

• #18 A survey of anaphylaxis etiology and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6352571/

  Identifying the causes of anaphylaxis which is an acute, potentially fatal systemic reaction is very important in every community. […] We sought to determine the most common triggers of anaphylaxis, clinical manifestations and treatment strategies in Mashhad, northeast of Iran. […] We used a combination of patients clinical history and allergy diagnostic testing including radioallergosorbant test and skin prick test in order to determine the etiology of anaphylaxis. […] The triggers included: foods, 61.4%; drugs, 15.7%; hymenoptera venom, 8.6%; idiopathic, 5.7%; immunotherapy, 4.3% and other etiologies: 5.7%. […] The most common cause of anaphylaxis during childhood (less than 19 years old) was food. […] In our study, in adults (over 20 years old), the most common causes of anaphylaxis were foods, medicines, hymenoptera venom, idiopathic and miscellaneous causes, respectively.

• #19 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  Anaphylaxis is a severe allergic reaction. […] Food allergies are one of the main causes of anaphylaxis. Other causes include stinging insects, medications and latex. […] Anaphylaxis usually begins with skin symptoms of hives or itching. […] What causes anaphylaxis? […] Food allergies are one of the main causes of anaphylaxis. Foods that can cause this severe anaphylactic reaction include: Cows milk, Eggs, Peanuts, Shellfish (shrimp and lobster), Soy, Tree nuts (like walnuts, hazelnuts, Brazil nuts and cashews), Wheat, Seeds (like sesame seeds and sunflower seeds). […] Other allergens (substances that cause allergies) that can lead to anaphylaxis include: Certain medications and substances, including penicillin, nonsteroidal anti-inflammatory drugs (NSAIDs) and dye used for CT scans. Latex, found in items such as disposable gloves, catheters and adhesive tapes. Insect stings from bees, wasps, hornets and yellow jackets.

• #20 A survey of anaphylaxis etiology and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6352571/

  In the current study, food anaphylaxis was mostly due to the consumption of nuts, especially walnut, peanut, as well as with lower incidence by fruit consumption. […] In our study, among medicines, antibiotics and topical anesthetics were the most common cause of medicine anaphylaxis. […] The most common manifestations of anaphylaxis were mucocutaneus (85.7%), cardiovascular (77.1%), respiratory (71.4%) and gastric (15.7%) manifestations, respectively. […] In summary, foods (nuts) are the most common triggers of anaphylaxis in Mashhad.

• #21 Anaphylaxis: Causes, Symptoms and Treatment | Allergy Insider

  https://www.thermofisher.com/allergy/us/en/living-with-allergies/symptom-management/anaphylaxis.html

  Here are some of the most common allergies that can cause anaphylaxis, along with some links to help you learn more about each one. […] While a wide range of foods may cause anaphylaxis, the most commonly implicated foods for both adults and children worldwide are: Peanuts, Tree nuts (e.g., almonds, Brazil nuts, cashew nuts, hazelnuts, macadamia nuts, pecans, pistachios, walnuts), Milk, Eggs, Sesame seeds, Fish, Shellfish. […] Anaphylaxis may also be caused by allergies to the following drugs and contrast agents: Penicillin and other antibiotics, Nonsteroidal anti-inflammatory drugs (NSAIDs), e.g., aspirin and aspirin-related products, Insulin, Muscle relaxants (e.g., suxamethonium, alcuronium, vecuronium, pancuronium, and atracurium, which are widely used in general anesthesia), Biologics and monoclonal antibodies, Contrast agents (i.e., special dyes to help internal body parts or functions show up better on scans).

• #22 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  Anaphylaxis is a severe allergic reaction. […] Food allergies are one of the main causes of anaphylaxis. Other causes include stinging insects, medications and latex. […] Anaphylaxis usually begins with skin symptoms of hives or itching. […] What causes anaphylaxis? […] Food allergies are one of the main causes of anaphylaxis. Foods that can cause this severe anaphylactic reaction include: Cows milk, Eggs, Peanuts, Shellfish (shrimp and lobster), Soy, Tree nuts (like walnuts, hazelnuts, Brazil nuts and cashews), Wheat, Seeds (like sesame seeds and sunflower seeds). […] Other allergens (substances that cause allergies) that can lead to anaphylaxis include: Certain medications and substances, including penicillin, nonsteroidal anti-inflammatory drugs (NSAIDs) and dye used for CT scans. Latex, found in items such as disposable gloves, catheters and adhesive tapes. Insect stings from bees, wasps, hornets and yellow jackets.

• #23 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  Anaphylaxis is a severe allergic reaction. […] Food allergies are one of the main causes of anaphylaxis. Other causes include stinging insects, medications and latex. […] Anaphylaxis usually begins with skin symptoms of hives or itching. […] What causes anaphylaxis? […] Food allergies are one of the main causes of anaphylaxis. Foods that can cause this severe anaphylactic reaction include: Cows milk, Eggs, Peanuts, Shellfish (shrimp and lobster), Soy, Tree nuts (like walnuts, hazelnuts, Brazil nuts and cashews), Wheat, Seeds (like sesame seeds and sunflower seeds). […] Other allergens (substances that cause allergies) that can lead to anaphylaxis include: Certain medications and substances, including penicillin, nonsteroidal anti-inflammatory drugs (NSAIDs) and dye used for CT scans. Latex, found in items such as disposable gloves, catheters and adhesive tapes. Insect stings from bees, wasps, hornets and yellow jackets.

• #24 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  Anaphylaxis is a severe allergic reaction. […] Food allergies are one of the main causes of anaphylaxis. Other causes include stinging insects, medications and latex. […] Anaphylaxis usually begins with skin symptoms of hives or itching. […] What causes anaphylaxis? […] Food allergies are one of the main causes of anaphylaxis. Foods that can cause this severe anaphylactic reaction include: Cows milk, Eggs, Peanuts, Shellfish (shrimp and lobster), Soy, Tree nuts (like walnuts, hazelnuts, Brazil nuts and cashews), Wheat, Seeds (like sesame seeds and sunflower seeds). […] Other allergens (substances that cause allergies) that can lead to anaphylaxis include: Certain medications and substances, including penicillin, nonsteroidal anti-inflammatory drugs (NSAIDs) and dye used for CT scans. Latex, found in items such as disposable gloves, catheters and adhesive tapes. Insect stings from bees, wasps, hornets and yellow jackets.

• #25 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  Anaphylaxis is a severe allergic reaction. […] Food allergies are one of the main causes of anaphylaxis. Other causes include stinging insects, medications and latex. […] Anaphylaxis usually begins with skin symptoms of hives or itching. […] What causes anaphylaxis? […] Food allergies are one of the main causes of anaphylaxis. Foods that can cause this severe anaphylactic reaction include: Cows milk, Eggs, Peanuts, Shellfish (shrimp and lobster), Soy, Tree nuts (like walnuts, hazelnuts, Brazil nuts and cashews), Wheat, Seeds (like sesame seeds and sunflower seeds). […] Other allergens (substances that cause allergies) that can lead to anaphylaxis include: Certain medications and substances, including penicillin, nonsteroidal anti-inflammatory drugs (NSAIDs) and dye used for CT scans. Latex, found in items such as disposable gloves, catheters and adhesive tapes. Insect stings from bees, wasps, hornets and yellow jackets.

• #26 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  Anaphylaxis is a severe allergic reaction. […] Food allergies are one of the main causes of anaphylaxis. Other causes include stinging insects, medications and latex. […] Anaphylaxis usually begins with skin symptoms of hives or itching. […] What causes anaphylaxis? […] Food allergies are one of the main causes of anaphylaxis. Foods that can cause this severe anaphylactic reaction include: Cows milk, Eggs, Peanuts, Shellfish (shrimp and lobster), Soy, Tree nuts (like walnuts, hazelnuts, Brazil nuts and cashews), Wheat, Seeds (like sesame seeds and sunflower seeds). […] Other allergens (substances that cause allergies) that can lead to anaphylaxis include: Certain medications and substances, including penicillin, nonsteroidal anti-inflammatory drugs (NSAIDs) and dye used for CT scans. Latex, found in items such as disposable gloves, catheters and adhesive tapes. Insect stings from bees, wasps, hornets and yellow jackets.

• #27 Anaphylaxis: Causes, Symptoms and Treatment | Allergy Insider

  https://www.thermofisher.com/allergy/us/en/living-with-allergies/symptom-management/anaphylaxis.html

  Here are some of the most common allergies that can cause anaphylaxis, along with some links to help you learn more about each one. […] While a wide range of foods may cause anaphylaxis, the most commonly implicated foods for both adults and children worldwide are: Peanuts, Tree nuts (e.g., almonds, Brazil nuts, cashew nuts, hazelnuts, macadamia nuts, pecans, pistachios, walnuts), Milk, Eggs, Sesame seeds, Fish, Shellfish. […] Anaphylaxis may also be caused by allergies to the following drugs and contrast agents: Penicillin and other antibiotics, Nonsteroidal anti-inflammatory drugs (NSAIDs), e.g., aspirin and aspirin-related products, Insulin, Muscle relaxants (e.g., suxamethonium, alcuronium, vecuronium, pancuronium, and atracurium, which are widely used in general anesthesia), Biologics and monoclonal antibodies, Contrast agents (i.e., special dyes to help internal body parts or functions show up better on scans).

• #28 Anaphylaxis (Anaphylactic Reaction): Symptoms, Causes, Treatment

  https://www.webmd.com/allergies/anaphylaxis

  Anaphylaxis happens when you have an antibody, something that usually fights infection, that reacts too much to something that should be harmless, like food. It might not happen the first time you come in contact with the trigger, but it can get worse over time. […] In children, the most common cause of anaphylaxis is food. For adults, medications more often cause it. […] Common food triggers for children are: Peanuts, Shellfish, Fish, Milk, Eggs, Soy, Wheat. […] Common food triggers for adults are: Shellfish, Tree nuts (walnuts, hazelnuts, cashews, pistachios, pine nuts, and almonds), Peanuts. […] Common medication triggers are: Penicillin (more often following a shot rather than a pill), Muscle relaxants like the ones used for anesthesia, Aspirin, ibuprofen, and other NSAIDs (nonsteroidal anti-inflammatory drugs), Anti-seizure medications.

• #29 Anaphylaxis Statistics – Allergy & Asthma Network

  https://allergyasthmanetwork.org/anaphylaxis/anaphylaxis-statistics/

  Anaphylaxis is caused by exposure to a trigger or allergen. The most common triggers include: […] In infants, food accounts for 73% of anaphylaxis symptoms. The most common trigger foods are egg, milk, peanut, and banana. Drugs account for 20% of anaphylaxis cases in infants, followed by unknown triggers. […] The fatality rate for an anaphylactic reaction in the United States is about 0.3%.

• #30

  https://chestercountyallergy.com/allergy-education/anaphylaxis/causes-of-anaphylaxis/

  Causes of Anaphylaxis […] Peanuts, tree nuts (walnuts, cashews, etc.), shellfish, fish, milk, and eggs commonly cause anaphylactic reactions. Only a trace amount of a problem food can cause a reaction in some individuals. […] In the United States, food-induced anaphylaxis is believed to cause about 30,000 trips to the emergency room and between 150 to 200 deaths each year. Individuals who are allergic to foods and have asthma are believed to be at a higher risk for developing an anaphylactic reaction. […] A study of 32 cases of fatal food-allergy induced anaphylaxis showed that adolescents who have peanut and tree nut allergy and asthma, and who dont have quick access to epinephrine during a reaction, are at highest risk for a fatal reaction. […] Anaphylactic reactions to medication will typically occur within an hour after taking the drug; however, reactions may occur several hours later. It is estimated that up to 10 percent of the population may be at risk for allergic reactions to medications. […] According to literature from The American Academy of Allergy, Asthma Immunology, The chances of developing an allergic reaction may be increased if the drug is given frequently, in large doses, or by injection rather than by pill. […] Honeybees, bumblebees, yellow jackets, hornets, wasps, fire ants, and harvester ants are the most common causes of insect stings in the United States. […] Latex allergy is most commonly diagnosed in individuals who are exposed to latex frequently, such as those employed in the health care or rubber industry fields and children with spina bifida and other congenital diseases requiring multiple surgeries. […] Food-dependent, exercise-induced anaphylaxis is very rare and occurs only when an individual eats a specific food and exercises within three to four hours after eating. […] Idiopathic anaphylaxis is a severe reaction in which no cause can be determined.

• #31 Anaphylaxis (Anaphylactic Reaction): Symptoms, Causes, Treatment

  https://www.webmd.com/allergies/anaphylaxis

  Anaphylaxis happens when you have an antibody, something that usually fights infection, that reacts too much to something that should be harmless, like food. It might not happen the first time you come in contact with the trigger, but it can get worse over time. […] In children, the most common cause of anaphylaxis is food. For adults, medications more often cause it. […] Common food triggers for children are: Peanuts, Shellfish, Fish, Milk, Eggs, Soy, Wheat. […] Common food triggers for adults are: Shellfish, Tree nuts (walnuts, hazelnuts, cashews, pistachios, pine nuts, and almonds), Peanuts. […] Common medication triggers are: Penicillin (more often following a shot rather than a pill), Muscle relaxants like the ones used for anesthesia, Aspirin, ibuprofen, and other NSAIDs (nonsteroidal anti-inflammatory drugs), Anti-seizure medications.

• #32 A survey of anaphylaxis etiology and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6352571/

  Identifying the causes of anaphylaxis which is an acute, potentially fatal systemic reaction is very important in every community. […] We sought to determine the most common triggers of anaphylaxis, clinical manifestations and treatment strategies in Mashhad, northeast of Iran. […] We used a combination of patients clinical history and allergy diagnostic testing including radioallergosorbant test and skin prick test in order to determine the etiology of anaphylaxis. […] The triggers included: foods, 61.4%; drugs, 15.7%; hymenoptera venom, 8.6%; idiopathic, 5.7%; immunotherapy, 4.3% and other etiologies: 5.7%. […] The most common cause of anaphylaxis during childhood (less than 19 years old) was food. […] In our study, in adults (over 20 years old), the most common causes of anaphylaxis were foods, medicines, hymenoptera venom, idiopathic and miscellaneous causes, respectively.

• #33 Anaphylaxis: Causes, Symptoms and Treatment | Allergy Insider

  https://www.thermofisher.com/allergy/us/en/living-with-allergies/symptom-management/anaphylaxis.html

  Anaphylaxis is a severe and potentially life-threatening allergic reaction. Like other allergy symptoms, its triggered when the immune system overreacts and releases histamine (among other chemicals) in response to an allergen, such as peanuts, shellfish, latex, insect venom, dust mites, and countless more. […] While there may be other causes of anaphylaxis, such as exercise, allergens are the main culprits. Among them, food allergens are the most frequent triggers of anaphylaxis in children, and insect venom and various drug allergies are the most prevalent offenders in adults. Additionally, according to an article published in The Journal of Allergy and Clinical Immunology, drugs are the most common reported cause of fatal anaphylaxis in countries such as Australia, New Zealand, the United Kingdom, Brazil, and the United States.

• #34 Anaphylaxis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/135065-overview

  An analysis of 32 fatalities thought to be due to food-induced anaphylaxis revealed that peanuts likely were the responsible food in 62% of the cases. […] Most cases of IgE-mediated drug anaphylaxis in the United States are due to penicillin and other beta-lactam antibiotics. […] Reactions to cephalosporins may occur in penicillin-allergic patients. […] Hymenoptera stings are a common cause of allergic reaction and anaphylaxis. […] Anaphylaxis may result from administration of blood products, including IV immunoglobulin, or animal antiserum, at least partly as a consequence of activation of the complement cascade. […] Exercise-induced anaphylaxis is a rare syndrome that can take 1 of 2 forms. […] Certain agents, including opioids, dextrans, protamine, and vancomycin, are thought to cause direct, nonimmunologic release of mediators from mast cells. […] Anaphylaxis can be a manifestation of systemic mastocytosis, a disease characterized by excessive mast cell burden in multiple organs.

• #35 Anaphylaxis: Causes, Symptoms and Treatment | Allergy Insider

  https://www.thermofisher.com/allergy/us/en/living-with-allergies/symptom-management/anaphylaxis.html

  Here are some of the most common allergies that can cause anaphylaxis, along with some links to help you learn more about each one. […] While a wide range of foods may cause anaphylaxis, the most commonly implicated foods for both adults and children worldwide are: Peanuts, Tree nuts (e.g., almonds, Brazil nuts, cashew nuts, hazelnuts, macadamia nuts, pecans, pistachios, walnuts), Milk, Eggs, Sesame seeds, Fish, Shellfish. […] Anaphylaxis may also be caused by allergies to the following drugs and contrast agents: Penicillin and other antibiotics, Nonsteroidal anti-inflammatory drugs (NSAIDs), e.g., aspirin and aspirin-related products, Insulin, Muscle relaxants (e.g., suxamethonium, alcuronium, vecuronium, pancuronium, and atracurium, which are widely used in general anesthesia), Biologics and monoclonal antibodies, Contrast agents (i.e., special dyes to help internal body parts or functions show up better on scans).

• #36 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Anaphylaxis-Causes.aspx

  There are several known triggers or causes of anaphylactic reactions. Some of the common and identifiable causes include: […] Penicillin is the most common cause of drug-induced anaphylaxis. […] Around 4% of those allergic to penicillins are also allergic to cephalosporins (another group of antibiotics) especially to first generation cephalosporins. […] Reactions to stings from bees, wasps and ants that belong to the order Hymenoptera are the second most common cause of anaphylaxis after drugs. […] There is a large variety of foods that a large population is allergic to. […] Food anaphylaxis is most common in children and young. […] Some people are also allergic to food additives, colorants and preservative chemicals as well. […] Some people are allergic to neuromuscular blocking agents or muscle relaxants used in anesthesia.

• #37 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Anaphylaxis-Causes.aspx

  There are several known triggers or causes of anaphylactic reactions. Some of the common and identifiable causes include: […] Penicillin is the most common cause of drug-induced anaphylaxis. […] Around 4% of those allergic to penicillins are also allergic to cephalosporins (another group of antibiotics) especially to first generation cephalosporins. […] Reactions to stings from bees, wasps and ants that belong to the order Hymenoptera are the second most common cause of anaphylaxis after drugs. […] There is a large variety of foods that a large population is allergic to. […] Food anaphylaxis is most common in children and young. […] Some people are also allergic to food additives, colorants and preservative chemicals as well. […] Some people are allergic to neuromuscular blocking agents or muscle relaxants used in anesthesia.

• #38 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  Anaphylaxis is a severe allergic reaction. […] Food allergies are one of the main causes of anaphylaxis. Other causes include stinging insects, medications and latex. […] Anaphylaxis usually begins with skin symptoms of hives or itching. […] What causes anaphylaxis? […] Food allergies are one of the main causes of anaphylaxis. Foods that can cause this severe anaphylactic reaction include: Cows milk, Eggs, Peanuts, Shellfish (shrimp and lobster), Soy, Tree nuts (like walnuts, hazelnuts, Brazil nuts and cashews), Wheat, Seeds (like sesame seeds and sunflower seeds). […] Other allergens (substances that cause allergies) that can lead to anaphylaxis include: Certain medications and substances, including penicillin, nonsteroidal anti-inflammatory drugs (NSAIDs) and dye used for CT scans. Latex, found in items such as disposable gloves, catheters and adhesive tapes. Insect stings from bees, wasps, hornets and yellow jackets.

• #39 Anaphylaxis: Causes, Symptoms and Treatment | Allergy Insider

  https://www.thermofisher.com/allergy/us/en/living-with-allergies/symptom-management/anaphylaxis.html

  Here are some of the most common allergies that can cause anaphylaxis, along with some links to help you learn more about each one. […] While a wide range of foods may cause anaphylaxis, the most commonly implicated foods for both adults and children worldwide are: Peanuts, Tree nuts (e.g., almonds, Brazil nuts, cashew nuts, hazelnuts, macadamia nuts, pecans, pistachios, walnuts), Milk, Eggs, Sesame seeds, Fish, Shellfish. […] Anaphylaxis may also be caused by allergies to the following drugs and contrast agents: Penicillin and other antibiotics, Nonsteroidal anti-inflammatory drugs (NSAIDs), e.g., aspirin and aspirin-related products, Insulin, Muscle relaxants (e.g., suxamethonium, alcuronium, vecuronium, pancuronium, and atracurium, which are widely used in general anesthesia), Biologics and monoclonal antibodies, Contrast agents (i.e., special dyes to help internal body parts or functions show up better on scans).

• #40 Anaphylaxis: Causes, Symptoms and Treatment | Allergy Insider

  https://www.thermofisher.com/allergy/us/en/living-with-allergies/symptom-management/anaphylaxis.html

  Here are some of the most common allergies that can cause anaphylaxis, along with some links to help you learn more about each one. […] While a wide range of foods may cause anaphylaxis, the most commonly implicated foods for both adults and children worldwide are: Peanuts, Tree nuts (e.g., almonds, Brazil nuts, cashew nuts, hazelnuts, macadamia nuts, pecans, pistachios, walnuts), Milk, Eggs, Sesame seeds, Fish, Shellfish. […] Anaphylaxis may also be caused by allergies to the following drugs and contrast agents: Penicillin and other antibiotics, Nonsteroidal anti-inflammatory drugs (NSAIDs), e.g., aspirin and aspirin-related products, Insulin, Muscle relaxants (e.g., suxamethonium, alcuronium, vecuronium, pancuronium, and atracurium, which are widely used in general anesthesia), Biologics and monoclonal antibodies, Contrast agents (i.e., special dyes to help internal body parts or functions show up better on scans).

• #41 Anaphylaxis: Causes, Symptoms and Treatment | Allergy Insider

  https://www.thermofisher.com/allergy/us/en/living-with-allergies/symptom-management/anaphylaxis.html

  Here are some of the most common allergies that can cause anaphylaxis, along with some links to help you learn more about each one. […] While a wide range of foods may cause anaphylaxis, the most commonly implicated foods for both adults and children worldwide are: Peanuts, Tree nuts (e.g., almonds, Brazil nuts, cashew nuts, hazelnuts, macadamia nuts, pecans, pistachios, walnuts), Milk, Eggs, Sesame seeds, Fish, Shellfish. […] Anaphylaxis may also be caused by allergies to the following drugs and contrast agents: Penicillin and other antibiotics, Nonsteroidal anti-inflammatory drugs (NSAIDs), e.g., aspirin and aspirin-related products, Insulin, Muscle relaxants (e.g., suxamethonium, alcuronium, vecuronium, pancuronium, and atracurium, which are widely used in general anesthesia), Biologics and monoclonal antibodies, Contrast agents (i.e., special dyes to help internal body parts or functions show up better on scans).

• #42 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Anaphylaxis-Causes.aspx

  There are several known triggers or causes of anaphylactic reactions. Some of the common and identifiable causes include: […] Penicillin is the most common cause of drug-induced anaphylaxis. […] Around 4% of those allergic to penicillins are also allergic to cephalosporins (another group of antibiotics) especially to first generation cephalosporins. […] Reactions to stings from bees, wasps and ants that belong to the order Hymenoptera are the second most common cause of anaphylaxis after drugs. […] There is a large variety of foods that a large population is allergic to. […] Food anaphylaxis is most common in children and young. […] Some people are also allergic to food additives, colorants and preservative chemicals as well. […] Some people are allergic to neuromuscular blocking agents or muscle relaxants used in anesthesia.

• #43 Anaphylaxis in the Operating Room: Practice Essentials, Problem, Management

  https://emedicine.medscape.com/article/2500072-overview

  Anaphylaxis is defined as an acute life-threatening systemic event triggered by the sudden release of mediators from basophils and mast cells after exposure to a triggering agent. [1, 2, 3, 4, 5, 6, 7] The pathway typically begins with the initial exposure to an agent and the production of immunoglobulin E (IgE) antibodies that then bind to mast cells and basophils. [1, 2, 4, 5, 8, 6] Upon reexposure to that agent or another with a related structure, the allergen forms crosslinks with the preexisting IgE antibodies, and this process culminates in the degranulation of mast cells and basophils and the manufacture of immune mediators. [1, 2, 7] […] […] The most common cause of anaphylaxis in the OR is the neuromuscular blocking agent, which has been cited as causative in 50-70% of cases. [1, 2, 3, 12, 4, 5, 10, 7, 11] Clinical presentation is often within minutes of induction or other use of the agent. [4] The mediators of the allergic reaction are IgE antibodies to the tertiary or quaternary ammonium groups to which patients become exposed through prior surgical procedures, other drugs, foods, or household items. [1, 9] […]

• #44 Anaphylaxis: Causes, Symptoms and Treatment | Allergy Insider

  https://www.thermofisher.com/allergy/us/en/living-with-allergies/symptom-management/anaphylaxis.html

  Here are some of the most common allergies that can cause anaphylaxis, along with some links to help you learn more about each one. […] While a wide range of foods may cause anaphylaxis, the most commonly implicated foods for both adults and children worldwide are: Peanuts, Tree nuts (e.g., almonds, Brazil nuts, cashew nuts, hazelnuts, macadamia nuts, pecans, pistachios, walnuts), Milk, Eggs, Sesame seeds, Fish, Shellfish. […] Anaphylaxis may also be caused by allergies to the following drugs and contrast agents: Penicillin and other antibiotics, Nonsteroidal anti-inflammatory drugs (NSAIDs), e.g., aspirin and aspirin-related products, Insulin, Muscle relaxants (e.g., suxamethonium, alcuronium, vecuronium, pancuronium, and atracurium, which are widely used in general anesthesia), Biologics and monoclonal antibodies, Contrast agents (i.e., special dyes to help internal body parts or functions show up better on scans).

• #45 Anaphylaxis – Immunology; Allergic Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/immunology-allergic-disorders/allergic-autoimmune-and-other-hypersensitivity-disorders/anaphylaxis

  Anaphylaxis is typically triggered by […] Common triggers of anaphylaxis include medications (eg, beta-lactam antibiotics, allergen extracts), foods (eg, nuts, seafood), proteins (eg, tetanus antitoxin, blood transfusions), animal venoms, and latex. […] NonIgE-mediated reactions that have anaphylactic-like manifestations (anaphylactoid reactions) can be caused by an iodinated radiopaque contrast agent, aspirin, other nonsteroidal anti-inflammatory drugs, opioids, monoclonal antibodies, and exercise.

• #46 Anaphylaxis

  https://www.nhs.uk/conditions/anaphylaxis/

  Anaphylaxis happens when your body has a serious reaction to something you’re allergic to. […] Allergies that can sometimes cause anaphylaxis include: foods such as nuts, cows’ milk, eggs, fish or sesame seeds, medicines such as antibiotics or non-steroidal anti-inflammatory drugs (NSAIDs), insect stings, such as wasp and bee stings, anaesthetics, latex (a type of rubber found in some rubber gloves and condoms). […] Sometimes it’s not known what caused an anaphylactic reaction.

• #47 Anaphylaxis: Causes and Risk Factors

  https://www.verywellhealth.com/anaphylaxis-causes-risk-factors-82703

  Anaphylaxis is a life-threatening allergic reaction that can be triggered by exposure to many different substances (allergens). The most common allergies that can produce anaphylaxis are to drugs, insects stings, foods, and latex. […] Anaphylaxis can occur in response to almost any allergen. However, common respiratory allergies such as hay fever and animal dander rarely cause anaphylaxis. […] Food allergies are the most common triggers of anaphylaxis in children, and among the top causes for adults. The foods most often responsible are peanuts, tree nuts (e.g., walnuts, hazelnuts, pecans, pistachios, cashews), fish, shellfish, chicken eggs, cow’s milk, wheat soy, and sesame. […] Medication allergies are a common cause of anaphylaxis in all age groups. The most common drugs that produce anaphylaxis are penicillin and non-steroidal anti-inflammatory drugs such as aspirin, Advil (ibuprofen), and Aleve (naproxen).

• #48

  https://chestercountyallergy.com/allergy-education/anaphylaxis/causes-of-anaphylaxis/

  Causes of Anaphylaxis […] Peanuts, tree nuts (walnuts, cashews, etc.), shellfish, fish, milk, and eggs commonly cause anaphylactic reactions. Only a trace amount of a problem food can cause a reaction in some individuals. […] In the United States, food-induced anaphylaxis is believed to cause about 30,000 trips to the emergency room and between 150 to 200 deaths each year. Individuals who are allergic to foods and have asthma are believed to be at a higher risk for developing an anaphylactic reaction. […] A study of 32 cases of fatal food-allergy induced anaphylaxis showed that adolescents who have peanut and tree nut allergy and asthma, and who dont have quick access to epinephrine during a reaction, are at highest risk for a fatal reaction. […] Anaphylactic reactions to medication will typically occur within an hour after taking the drug; however, reactions may occur several hours later. It is estimated that up to 10 percent of the population may be at risk for allergic reactions to medications. […] According to literature from The American Academy of Allergy, Asthma Immunology, The chances of developing an allergic reaction may be increased if the drug is given frequently, in large doses, or by injection rather than by pill. […] Honeybees, bumblebees, yellow jackets, hornets, wasps, fire ants, and harvester ants are the most common causes of insect stings in the United States. […] Latex allergy is most commonly diagnosed in individuals who are exposed to latex frequently, such as those employed in the health care or rubber industry fields and children with spina bifida and other congenital diseases requiring multiple surgeries. […] Food-dependent, exercise-induced anaphylaxis is very rare and occurs only when an individual eats a specific food and exercises within three to four hours after eating. […] Idiopathic anaphylaxis is a severe reaction in which no cause can be determined.

• #49

  https://chestercountyallergy.com/allergy-education/anaphylaxis/causes-of-anaphylaxis/

  Causes of Anaphylaxis […] Peanuts, tree nuts (walnuts, cashews, etc.), shellfish, fish, milk, and eggs commonly cause anaphylactic reactions. Only a trace amount of a problem food can cause a reaction in some individuals. […] In the United States, food-induced anaphylaxis is believed to cause about 30,000 trips to the emergency room and between 150 to 200 deaths each year. Individuals who are allergic to foods and have asthma are believed to be at a higher risk for developing an anaphylactic reaction. […] A study of 32 cases of fatal food-allergy induced anaphylaxis showed that adolescents who have peanut and tree nut allergy and asthma, and who dont have quick access to epinephrine during a reaction, are at highest risk for a fatal reaction. […] Anaphylactic reactions to medication will typically occur within an hour after taking the drug; however, reactions may occur several hours later. It is estimated that up to 10 percent of the population may be at risk for allergic reactions to medications. […] According to literature from The American Academy of Allergy, Asthma Immunology, The chances of developing an allergic reaction may be increased if the drug is given frequently, in large doses, or by injection rather than by pill. […] Honeybees, bumblebees, yellow jackets, hornets, wasps, fire ants, and harvester ants are the most common causes of insect stings in the United States. […] Latex allergy is most commonly diagnosed in individuals who are exposed to latex frequently, such as those employed in the health care or rubber industry fields and children with spina bifida and other congenital diseases requiring multiple surgeries. […] Food-dependent, exercise-induced anaphylaxis is very rare and occurs only when an individual eats a specific food and exercises within three to four hours after eating. […] Idiopathic anaphylaxis is a severe reaction in which no cause can be determined.

• #50

  https://chestercountyallergy.com/allergy-education/anaphylaxis/causes-of-anaphylaxis/

  Causes of Anaphylaxis […] Peanuts, tree nuts (walnuts, cashews, etc.), shellfish, fish, milk, and eggs commonly cause anaphylactic reactions. Only a trace amount of a problem food can cause a reaction in some individuals. […] In the United States, food-induced anaphylaxis is believed to cause about 30,000 trips to the emergency room and between 150 to 200 deaths each year. Individuals who are allergic to foods and have asthma are believed to be at a higher risk for developing an anaphylactic reaction. […] A study of 32 cases of fatal food-allergy induced anaphylaxis showed that adolescents who have peanut and tree nut allergy and asthma, and who dont have quick access to epinephrine during a reaction, are at highest risk for a fatal reaction. […] Anaphylactic reactions to medication will typically occur within an hour after taking the drug; however, reactions may occur several hours later. It is estimated that up to 10 percent of the population may be at risk for allergic reactions to medications. […] According to literature from The American Academy of Allergy, Asthma Immunology, The chances of developing an allergic reaction may be increased if the drug is given frequently, in large doses, or by injection rather than by pill. […] Honeybees, bumblebees, yellow jackets, hornets, wasps, fire ants, and harvester ants are the most common causes of insect stings in the United States. […] Latex allergy is most commonly diagnosed in individuals who are exposed to latex frequently, such as those employed in the health care or rubber industry fields and children with spina bifida and other congenital diseases requiring multiple surgeries. […] Food-dependent, exercise-induced anaphylaxis is very rare and occurs only when an individual eats a specific food and exercises within three to four hours after eating. […] Idiopathic anaphylaxis is a severe reaction in which no cause can be determined.

• #51 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Anaphylaxis-Causes.aspx

  There are several known triggers or causes of anaphylactic reactions. Some of the common and identifiable causes include: […] Penicillin is the most common cause of drug-induced anaphylaxis. […] Around 4% of those allergic to penicillins are also allergic to cephalosporins (another group of antibiotics) especially to first generation cephalosporins. […] Reactions to stings from bees, wasps and ants that belong to the order Hymenoptera are the second most common cause of anaphylaxis after drugs. […] There is a large variety of foods that a large population is allergic to. […] Food anaphylaxis is most common in children and young. […] Some people are also allergic to food additives, colorants and preservative chemicals as well. […] Some people are allergic to neuromuscular blocking agents or muscle relaxants used in anesthesia.

• #52 A survey of anaphylaxis etiology and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6352571/

  Identifying the causes of anaphylaxis which is an acute, potentially fatal systemic reaction is very important in every community. […] We sought to determine the most common triggers of anaphylaxis, clinical manifestations and treatment strategies in Mashhad, northeast of Iran. […] We used a combination of patients clinical history and allergy diagnostic testing including radioallergosorbant test and skin prick test in order to determine the etiology of anaphylaxis. […] The triggers included: foods, 61.4%; drugs, 15.7%; hymenoptera venom, 8.6%; idiopathic, 5.7%; immunotherapy, 4.3% and other etiologies: 5.7%. […] The most common cause of anaphylaxis during childhood (less than 19 years old) was food. […] In our study, in adults (over 20 years old), the most common causes of anaphylaxis were foods, medicines, hymenoptera venom, idiopathic and miscellaneous causes, respectively.

• #53 Anaphylaxis | Causes, Symptoms & Treatment | ACAAI Public Website

  https://acaai.org/allergies/symptoms/anaphylaxis/

  Anaphylaxis is a rare but severe allergic reaction. It can occur suddenly, can worsen quickly and can be deadly. […] This severe reaction happens when an over-release of chemicals puts the person into shock. Allergies to food, insect stings, medications and latex are most frequently associated with anaphylaxis. […] If you have a history of allergies and/or asthma and have previously had a severe reaction, you are at greater risk for anaphylaxis. […] The most common triggers are: Food: including peanuts, tree nuts such as cashews and pistachio, fish, shellfish, cow’s milk, eggs and sesame. […] Latex: found in disposable gloves, intravenous tubes, syringes, adhesive tapes and catheters. […] Medication: including penicillin and other antibiotics, aspirin and non-steroidal anti-inflammatory drugs such as ibuprofen, and medications used for anesthesia. […] Insect sting: with bees, wasps, hornets, yellow jackets and fire ants being the most likely to trigger anaphylaxis.

• #54 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Anaphylaxis-Causes.aspx

  Hymenopteran sting venom, insect saliva, and other venoms: bees, wasps, ants, hornets, ticks, triatomid bugs, snakes, scorpions, jelly fish. […] Environmental: pollen, horse dander, hydatid cyst rupture. […] Physical factors: exercise, cold, heat. […] Medications and biologic agents: opiates, aspirin and NSAIDs, ACEI, vancomycin, radiocontrast media, N-acetylcysteine, fluorescein. […] Food additives: metabisulphite, tartrazine. […] Idiopathic no cause is known.

• #55 Anaphylaxis: Causes, Symptoms and Treatment | Allergy Insider

  https://www.thermofisher.com/allergy/us/en/living-with-allergies/symptom-management/anaphylaxis.html

  Venom from stinging insects (such as bees, yellow jackets, wasps, and hornets) and bites from fire ants may cause anaphylaxis. Anaphylaxis caused by insect-venom allergy has been reported in 3 percent of adults and 1 percent of children whove been stung. Additionally 80 to 90 percent of fatal insect venom anaphylaxis occurs in men 50 to 60 years old on average.

• #56 Anaphylaxis: Causes, Symptoms and Treatment | Allergy Insider

  https://www.thermofisher.com/allergy/us/en/living-with-allergies/symptom-management/anaphylaxis.html

  Venom from stinging insects (such as bees, yellow jackets, wasps, and hornets) and bites from fire ants may cause anaphylaxis. Anaphylaxis caused by insect-venom allergy has been reported in 3 percent of adults and 1 percent of children whove been stung. Additionally 80 to 90 percent of fatal insect venom anaphylaxis occurs in men 50 to 60 years old on average.

• #57 7 Surprising Triggers of Anaphylaxis

  https://www.everydayhealth.com/anaphylaxis/surprising-triggers-anaphylaxis-attack/

  Peanuts and shellfish aren’t the only causes of anaphylaxis. Here are some more triggers you should be aware of. The best-known triggers for anaphylaxis, a severe allergic reaction, are foods like peanuts, tree nuts (such as walnuts), eggs, shellfish, and milk. But foods like these are responsible for just 6.7 percent of fatal cases of anaphylaxis, according to a study published in 2014. It may surprise many people to learn that drugs and blood products are the most common causes of anaphylaxis deaths, according to the study. Some other surprising causes of anaphylactic reactions include exercising, eating red meat, or even having your period though these are not nearly as likely to be fatal reactions. Sperm allergy, also called semen allergy, is a rare cause of anaphylaxis but can cause life-threatening symptoms in women who have it during or after intercourse with a man. It seems to be more common in women who have allergic asthma or atopic dermatitis. In some cases, the anaphylactic reaction occurs because the woman’s partner ate something or took a drug that she’s allergic to, which is then transferred through his semen. In other cases, it’s an allergy to seminal plasma protein, a natural component of semen. Some women experience anaphylaxis just before or during their menstrual cycle. Known as catamenial, or cyclic, anaphylaxis, this rare disorder often goes unrecognized. Most patients, and even healthcare providers, aren’t aware of the association between anaphylaxis and the menstrual cycle. In some cases, the culprit is a medication or food consumed around the time of menstruation. At other times, though, no cause can be found. Meat from mammals can cause symptoms of anaphylaxis hours after you eat it, making it difficult to draw a connection between the food and your allergy. With this form of anaphylaxis, you may not experience symptoms until three to six hours later. A bite from a tick called the lone star tick can cause this allergy. As many as 90 to 100 people in the United States die each year because of a severe allergic reaction to an insect sting. Bees, hornets, and wasps including yellow jackets and fire ants are the insects whose stings are most likely to cause a severe anaphylactic reaction. Sometimes, anaphylaxis happens for unknown reasons. A person is sitting there, watching TV, and has an allergic reaction. If you have a sudden and unexplained allergic reaction, your doctor will probably take a complete history and ask a lot of questions, such as: What did you eat or drink? Did you exercise? Did you take medication? But sometimes, you’ll never know what triggered it. This situation baffles doctors and patients, but it’s not uncommon. In fact, 39 percent of people with anaphylaxis may have had a reaction that can’t be explained by a known trigger.

• #58 Anaphylaxis | Causes, Symptoms & Treatment | ACAAI Public Website

  https://acaai.org/allergies/symptoms/anaphylaxis/

  Anaphylaxis is a rare but severe allergic reaction. It can occur suddenly, can worsen quickly and can be deadly. […] This severe reaction happens when an over-release of chemicals puts the person into shock. Allergies to food, insect stings, medications and latex are most frequently associated with anaphylaxis. […] If you have a history of allergies and/or asthma and have previously had a severe reaction, you are at greater risk for anaphylaxis. […] The most common triggers are: Food: including peanuts, tree nuts such as cashews and pistachio, fish, shellfish, cow’s milk, eggs and sesame. […] Latex: found in disposable gloves, intravenous tubes, syringes, adhesive tapes and catheters. […] Medication: including penicillin and other antibiotics, aspirin and non-steroidal anti-inflammatory drugs such as ibuprofen, and medications used for anesthesia. […] Insect sting: with bees, wasps, hornets, yellow jackets and fire ants being the most likely to trigger anaphylaxis.

• #59 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  Anaphylaxis is a severe allergic reaction. […] Food allergies are one of the main causes of anaphylaxis. Other causes include stinging insects, medications and latex. […] Anaphylaxis usually begins with skin symptoms of hives or itching. […] What causes anaphylaxis? […] Food allergies are one of the main causes of anaphylaxis. Foods that can cause this severe anaphylactic reaction include: Cows milk, Eggs, Peanuts, Shellfish (shrimp and lobster), Soy, Tree nuts (like walnuts, hazelnuts, Brazil nuts and cashews), Wheat, Seeds (like sesame seeds and sunflower seeds). […] Other allergens (substances that cause allergies) that can lead to anaphylaxis include: Certain medications and substances, including penicillin, nonsteroidal anti-inflammatory drugs (NSAIDs) and dye used for CT scans. Latex, found in items such as disposable gloves, catheters and adhesive tapes. Insect stings from bees, wasps, hornets and yellow jackets.

• #60 Anaphylaxis (Anaphylactic Reaction): Symptoms, Causes, Treatment

  https://www.webmd.com/allergies/anaphylaxis

  Anaphylaxis also can be triggered by a few other things. But these aren’t as common: Pollen, such as ragweed, grass, and tree pollen, Stings or bites from bees, wasps, yellow jackets, hornets, and fire ants, Latex, found in hospital gloves, balloons, and rubber bands. […] Some people can have an anaphylactic reaction if they breathe in latex. […] In rare cases, it can be triggered by two to four hours of exercise after eating certain foods or by exercise on its own. […] Anaphylactic reactions usually start within minutes of contact with the trigger, but they can also happen an hour or more later. […] Some people never figure out what caused their reactions. That’s known as idiopathic anaphylaxis. If you don’t know your triggers, you can’t avoid them.

• #61

  https://chestercountyallergy.com/allergy-education/anaphylaxis/causes-of-anaphylaxis/

  Causes of Anaphylaxis […] Peanuts, tree nuts (walnuts, cashews, etc.), shellfish, fish, milk, and eggs commonly cause anaphylactic reactions. Only a trace amount of a problem food can cause a reaction in some individuals. […] In the United States, food-induced anaphylaxis is believed to cause about 30,000 trips to the emergency room and between 150 to 200 deaths each year. Individuals who are allergic to foods and have asthma are believed to be at a higher risk for developing an anaphylactic reaction. […] A study of 32 cases of fatal food-allergy induced anaphylaxis showed that adolescents who have peanut and tree nut allergy and asthma, and who dont have quick access to epinephrine during a reaction, are at highest risk for a fatal reaction. […] Anaphylactic reactions to medication will typically occur within an hour after taking the drug; however, reactions may occur several hours later. It is estimated that up to 10 percent of the population may be at risk for allergic reactions to medications. […] According to literature from The American Academy of Allergy, Asthma Immunology, The chances of developing an allergic reaction may be increased if the drug is given frequently, in large doses, or by injection rather than by pill. […] Honeybees, bumblebees, yellow jackets, hornets, wasps, fire ants, and harvester ants are the most common causes of insect stings in the United States. […] Latex allergy is most commonly diagnosed in individuals who are exposed to latex frequently, such as those employed in the health care or rubber industry fields and children with spina bifida and other congenital diseases requiring multiple surgeries. […] Food-dependent, exercise-induced anaphylaxis is very rare and occurs only when an individual eats a specific food and exercises within three to four hours after eating. […] Idiopathic anaphylaxis is a severe reaction in which no cause can be determined.

• #62 Anaphylaxis in the Operating Room: Practice Essentials, Problem, Management

  https://emedicine.medscape.com/article/2500072-overview

  Latex is responsible for another 16.9% of anaphylactic reactions in the general OR. [1, 12, 5, 9, 7] However, for the pediatric population, latex allergy is of particular significance, accounting for 80% of all intraoperative anaphylactic events. [1] […] […] Antibiotics are the third most common causative agent of anaphylactic reactions in the perioperative period (8% incidence). [1, 2, 5, 9, 6, 7] The beta-lactams, including penicillin, cephalosporins, ampicillin, amoxicillin, carbapenems, and monobactams, account for as many as 75% of all deaths from anaphylaxis in the United States. [1, 18, 6] […] […] Multiple other agents used in the perioperative period have been implicated in intraoperative anaphylaxis, including the following [1, 2, 3, 4, 19, 7] : Bone cement, Local anesthetics, with esters being more common causes of anaphylaxis than amides, Colloids (eg, albumin, dextran, and hetastarch [hydroxyethyl starch]), Cleaning solutions (eg, chlorhexidine and povidone-iodine), Coagulation agents (eg, heparin and aprotinin), Sugammadex, Induction drugs (eg, opioids, barbiturates, benzodiazepines, and propofol). The incidence of anaphylactic reactions with each of these agents is small. [1, 2, 3, 12, 9, 7]

• #63 Anaphylaxis – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/anaphylaxis/symptoms-causes/syc-20351468

  Anaphylaxis causes the immune system to release a flood of chemicals that can cause you to go into shock blood pressure drops suddenly and the airways narrow, blocking breathing. […] Allergy symptoms aren’t usually life-threatening, but a severe allergic reaction can lead to anaphylaxis. […] The most common anaphylaxis triggers in children are food allergies, such as to peanuts and tree nuts, fish, shellfish, wheat, soy, sesame and milk. […] Besides allergy to peanuts, nuts, fish, sesame and shellfish, anaphylaxis triggers in adults include: […] Although not common, some people develop anaphylaxis from aerobic exercise, such as jogging, or even less intense physical activity, such as walking. […] If you don’t know what triggers an allergy attack, certain tests can help identify the allergen. In some cases, the cause of anaphylaxis is not identified (idiopathic anaphylaxis).

• #64 Anaphylaxis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/135065-overview

  An analysis of 32 fatalities thought to be due to food-induced anaphylaxis revealed that peanuts likely were the responsible food in 62% of the cases. […] Most cases of IgE-mediated drug anaphylaxis in the United States are due to penicillin and other beta-lactam antibiotics. […] Reactions to cephalosporins may occur in penicillin-allergic patients. […] Hymenoptera stings are a common cause of allergic reaction and anaphylaxis. […] Anaphylaxis may result from administration of blood products, including IV immunoglobulin, or animal antiserum, at least partly as a consequence of activation of the complement cascade. […] Exercise-induced anaphylaxis is a rare syndrome that can take 1 of 2 forms. […] Certain agents, including opioids, dextrans, protamine, and vancomycin, are thought to cause direct, nonimmunologic release of mediators from mast cells. […] Anaphylaxis can be a manifestation of systemic mastocytosis, a disease characterized by excessive mast cell burden in multiple organs.

• #65

  https://chestercountyallergy.com/allergy-education/anaphylaxis/causes-of-anaphylaxis/

  Causes of Anaphylaxis […] Peanuts, tree nuts (walnuts, cashews, etc.), shellfish, fish, milk, and eggs commonly cause anaphylactic reactions. Only a trace amount of a problem food can cause a reaction in some individuals. […] In the United States, food-induced anaphylaxis is believed to cause about 30,000 trips to the emergency room and between 150 to 200 deaths each year. Individuals who are allergic to foods and have asthma are believed to be at a higher risk for developing an anaphylactic reaction. […] A study of 32 cases of fatal food-allergy induced anaphylaxis showed that adolescents who have peanut and tree nut allergy and asthma, and who dont have quick access to epinephrine during a reaction, are at highest risk for a fatal reaction. […] Anaphylactic reactions to medication will typically occur within an hour after taking the drug; however, reactions may occur several hours later. It is estimated that up to 10 percent of the population may be at risk for allergic reactions to medications. […] According to literature from The American Academy of Allergy, Asthma Immunology, The chances of developing an allergic reaction may be increased if the drug is given frequently, in large doses, or by injection rather than by pill. […] Honeybees, bumblebees, yellow jackets, hornets, wasps, fire ants, and harvester ants are the most common causes of insect stings in the United States. […] Latex allergy is most commonly diagnosed in individuals who are exposed to latex frequently, such as those employed in the health care or rubber industry fields and children with spina bifida and other congenital diseases requiring multiple surgeries. […] Food-dependent, exercise-induced anaphylaxis is very rare and occurs only when an individual eats a specific food and exercises within three to four hours after eating. […] Idiopathic anaphylaxis is a severe reaction in which no cause can be determined.

• #66 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Anaphylaxis-Causes.aspx

  The risk of occurrence of these events are 1 in 3500 to 1 in 20000 and 4% of these reactions may be fatal. […] This may be associated with previous intake of food or an allergic medication like Aspirin or an NSAID. […] In these cases the cause is not identified. […] This type occurs in the presence of other diseases that use medications which again raise the risk of anaphylaxis. […] These individuals are prone to allergies and anaphylactic shock both due to their disease condition as well as the medication that they take. […] Summary of causes of anaphylaxis: Drugs, chemicals and biologic agents: penicillins, cephalosporins, sulphonamides, muscle relaxants, vaccines, insulin, thiamine, protamine, gamma globulin, antivenoms, formaldehyde, ethylene oxide, chlorhexidine, semen. […] Foods: peanuts, tree nuts, shellfish, fin fish, milk, egg, fruits, vegetables, flour.

• #67 Anaphlactic Shock Causes | What Triggers Anaphylaxis

  https://www.nationaljewish.org/conditions/anaphylaxis/causes

  An anaphylactic reaction is often triggered by an allergen exposure. An exposure may occur through injection, swallowing, inhaling or skin contact. […] Include bee, hornet, wasp and yellow jacket stings, and allergen extracts used for diagnosis and treatment of allergic conditions. Antibiotics such as penicillin can trigger a reaction by injection or ingestion (swallowing). […] A severe reaction caused by a food allergy occurs after eating that particular food, even a small bite. Foods that most commonly cause anaphylaxis are peanuts, seafood, nuts and, in children, eggs and cow’s milk. Skin contact with the food rarely causes anaphylaxis. […] An anaphylactic reaction from an inhaled allergen is rare. An example is a latex-allergic person who inhales particles from rubber gloves or other latex products. […] For some people, two or more factors may be needed to cause anaphylaxis. It has been recognized that an anaphylactic reaction can occur if a person eats a certain food and then exercises. Neither the food alone nor exercise alone causes any problem, but the two together do.

• #68 Anaphylaxis

  https://www.nhs.uk/conditions/anaphylaxis/

  Anaphylaxis happens when your body has a serious reaction to something you’re allergic to. […] Allergies that can sometimes cause anaphylaxis include: foods such as nuts, cows’ milk, eggs, fish or sesame seeds, medicines such as antibiotics or non-steroidal anti-inflammatory drugs (NSAIDs), insect stings, such as wasp and bee stings, anaesthetics, latex (a type of rubber found in some rubber gloves and condoms). […] Sometimes it’s not known what caused an anaphylactic reaction.

• #69 Anaphylaxis – Allergy & Asthma Network

  https://allergyasthmanetwork.org/anaphylaxis/

  Anaphylaxis is caused by an exposure or ingestion of something to which you are allergic. The immune system then over-reacts. […] Anaphylaxis occurs when symptoms affect two or more body systems. It is caused by your immune system flooding your body with chemicals to fight off an allergen. These chemicals often work fast to trigger a cascade of allergy symptoms. […] Common anaphylaxis triggers are usually caused by a reaction to one of the following: food, insect venom, medication, latex, vaccines (in rare cases). […] Anaphylaxis is caused by your immune system. However, it can effect multiple body systems. This includes your skin, respiratory, digestive and heart systems. […] Anaphylaxis can be fatal. Deaths are often related to a delay in giving epinephrine or not giving epinephrine at all. […] You may have heard of people that develop anaphylactic symptoms for no apparent reason. This is rare, but it is a condition known as idiopathic anaphylaxis. This is the diagnosis when there is no known cause to symptoms.

• #70 Anaphylaxis – Wikipedia

  https://en.wikipedia.org/wiki/Anaphylaxis

  Common causes include allergies to insect bites and stings, allergies to foods including nuts, milk, fish, shellfish, eggs and some fresh fruits or dried fruits; allergies to sulfites a class of food preservatives and a byproduct in some fermented foods like vinegar; allergies to medications including some antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin; allergy to general anaesthetic (used to make people sleep during surgery); allergy to contrast agents dyes used in some medical tests to help certain areas of the body show up better on scans; allergy to latex a type of rubber found in some rubber gloves and condoms.[6][1] […] Anaphylaxis can occur in response to almost any foreign substance.[20] Common triggers include venom from insect bites or stings, foods, and medication.[10][21] Foods are the most common trigger in children and young adults, while medications and insect bites and stings are more common in older adults.[3] […] The cause remains unknown in 32-50% of cases, referred to as „idiopathic anaphylaxis.”[28] Six vaccines (MMR, varicella, influenza, hepatitis B, tetanus, meningococcal) are recognized as a cause for anaphylaxis, and HPV may cause anaphylaxis as well.[29]

• #71 A survey of anaphylaxis etiology and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6352571/

  Identifying the causes of anaphylaxis which is an acute, potentially fatal systemic reaction is very important in every community. […] We sought to determine the most common triggers of anaphylaxis, clinical manifestations and treatment strategies in Mashhad, northeast of Iran. […] We used a combination of patients clinical history and allergy diagnostic testing including radioallergosorbant test and skin prick test in order to determine the etiology of anaphylaxis. […] The triggers included: foods, 61.4%; drugs, 15.7%; hymenoptera venom, 8.6%; idiopathic, 5.7%; immunotherapy, 4.3% and other etiologies: 5.7%. […] The most common cause of anaphylaxis during childhood (less than 19 years old) was food. […] In our study, in adults (over 20 years old), the most common causes of anaphylaxis were foods, medicines, hymenoptera venom, idiopathic and miscellaneous causes, respectively.

• #72 Idiopathic Anaphylaxis | Anaphylaxis UK

  https://www.anaphylaxis.org.uk/fact-sheet/idiopathic-anaphylaxis/

  Anaphylaxis (pronounced ana-fil-ax-is) is a severe and potentially life-threatening allergic reaction. The common causes of anaphylaxis include food, insect stings, latex and medicines, but sometimes there may be no obvious trigger for the reaction. […] If after medical testing and investigation the cause of the reaction is not found, the reaction is then labelled as idiopathic anaphylaxis (which means cause unknown). This does not necessarily mean the reaction took place without something triggering it; it simply means that no trigger can be identified. […] Sometimes it could mean there is an unusual external trigger, such as a rare food allergen for which there is no skin or blood test, or which tests fail to pick up. […] A diagnosis of idiopathic anaphylaxis should only be made after an extensive medical investigation. This should include a review of all hospitalisation and AE records.

• #73 Idiopathic Anaphylaxis | Anaphylaxis UK

  https://www.anaphylaxis.org.uk/fact-sheet/idiopathic-anaphylaxis/

  Anaphylaxis (pronounced ana-fil-ax-is) is a severe and potentially life-threatening allergic reaction. The common causes of anaphylaxis include food, insect stings, latex and medicines, but sometimes there may be no obvious trigger for the reaction. […] If after medical testing and investigation the cause of the reaction is not found, the reaction is then labelled as idiopathic anaphylaxis (which means cause unknown). This does not necessarily mean the reaction took place without something triggering it; it simply means that no trigger can be identified. […] Sometimes it could mean there is an unusual external trigger, such as a rare food allergen for which there is no skin or blood test, or which tests fail to pick up. […] A diagnosis of idiopathic anaphylaxis should only be made after an extensive medical investigation. This should include a review of all hospitalisation and AE records.

• #74 Idiopathic Anaphylaxis | Anaphylaxis UK

  https://www.anaphylaxis.org.uk/fact-sheet/idiopathic-anaphylaxis/

  Food should be considered as a prime suspect. Foods eaten a few minutes before the start of an attack are the most likely culprits. […] Prescribed drugs, insect stings and latex may also be considered as the cause of the reaction. […] Some cases of idiopathic anaphylaxis have an internal cause a temporary increase in the reactivity of the immune system. […] A surprising and unexpected cause of anaphylaxis was discovered in the USA. An allergen in red meat can lead to anaphylaxis several hours after being eaten if the affected person has been previously sensitised. […] PEG, also known as macrogol or E1521, is a commonly used bulking and stabilizing agent. It is used in some medications, household products, cosmetics and processed foods. […] For a small minority of people, anaphylaxis can occur when a combination of factors is present together. This makes diagnosis difficult and without a thorough investigation the symptoms may be classed as idiopathic.

• #75 7 Surprising Triggers of Anaphylaxis

  https://www.everydayhealth.com/anaphylaxis/surprising-triggers-anaphylaxis-attack/

  Peanuts and shellfish aren’t the only causes of anaphylaxis. Here are some more triggers you should be aware of. The best-known triggers for anaphylaxis, a severe allergic reaction, are foods like peanuts, tree nuts (such as walnuts), eggs, shellfish, and milk. But foods like these are responsible for just 6.7 percent of fatal cases of anaphylaxis, according to a study published in 2014. It may surprise many people to learn that drugs and blood products are the most common causes of anaphylaxis deaths, according to the study. Some other surprising causes of anaphylactic reactions include exercising, eating red meat, or even having your period though these are not nearly as likely to be fatal reactions. Sperm allergy, also called semen allergy, is a rare cause of anaphylaxis but can cause life-threatening symptoms in women who have it during or after intercourse with a man. It seems to be more common in women who have allergic asthma or atopic dermatitis. In some cases, the anaphylactic reaction occurs because the woman’s partner ate something or took a drug that she’s allergic to, which is then transferred through his semen. In other cases, it’s an allergy to seminal plasma protein, a natural component of semen. Some women experience anaphylaxis just before or during their menstrual cycle. Known as catamenial, or cyclic, anaphylaxis, this rare disorder often goes unrecognized. Most patients, and even healthcare providers, aren’t aware of the association between anaphylaxis and the menstrual cycle. In some cases, the culprit is a medication or food consumed around the time of menstruation. At other times, though, no cause can be found. Meat from mammals can cause symptoms of anaphylaxis hours after you eat it, making it difficult to draw a connection between the food and your allergy. With this form of anaphylaxis, you may not experience symptoms until three to six hours later. A bite from a tick called the lone star tick can cause this allergy. As many as 90 to 100 people in the United States die each year because of a severe allergic reaction to an insect sting. Bees, hornets, and wasps including yellow jackets and fire ants are the insects whose stings are most likely to cause a severe anaphylactic reaction. Sometimes, anaphylaxis happens for unknown reasons. A person is sitting there, watching TV, and has an allergic reaction. If you have a sudden and unexplained allergic reaction, your doctor will probably take a complete history and ask a lot of questions, such as: What did you eat or drink? Did you exercise? Did you take medication? But sometimes, you’ll never know what triggered it. This situation baffles doctors and patients, but it’s not uncommon. In fact, 39 percent of people with anaphylaxis may have had a reaction that can’t be explained by a known trigger.

• #76 Idiopathic Anaphylaxis | Anaphylaxis UK

  https://www.anaphylaxis.org.uk/fact-sheet/idiopathic-anaphylaxis/

  Food should be considered as a prime suspect. Foods eaten a few minutes before the start of an attack are the most likely culprits. […] Prescribed drugs, insect stings and latex may also be considered as the cause of the reaction. […] Some cases of idiopathic anaphylaxis have an internal cause a temporary increase in the reactivity of the immune system. […] A surprising and unexpected cause of anaphylaxis was discovered in the USA. An allergen in red meat can lead to anaphylaxis several hours after being eaten if the affected person has been previously sensitised. […] PEG, also known as macrogol or E1521, is a commonly used bulking and stabilizing agent. It is used in some medications, household products, cosmetics and processed foods. […] For a small minority of people, anaphylaxis can occur when a combination of factors is present together. This makes diagnosis difficult and without a thorough investigation the symptoms may be classed as idiopathic.

• #77 Anaphylaxis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/135065-overview

  An analysis of 32 fatalities thought to be due to food-induced anaphylaxis revealed that peanuts likely were the responsible food in 62% of the cases. […] Most cases of IgE-mediated drug anaphylaxis in the United States are due to penicillin and other beta-lactam antibiotics. […] Reactions to cephalosporins may occur in penicillin-allergic patients. […] Hymenoptera stings are a common cause of allergic reaction and anaphylaxis. […] Anaphylaxis may result from administration of blood products, including IV immunoglobulin, or animal antiserum, at least partly as a consequence of activation of the complement cascade. […] Exercise-induced anaphylaxis is a rare syndrome that can take 1 of 2 forms. […] Certain agents, including opioids, dextrans, protamine, and vancomycin, are thought to cause direct, nonimmunologic release of mediators from mast cells. […] Anaphylaxis can be a manifestation of systemic mastocytosis, a disease characterized by excessive mast cell burden in multiple organs.

• #78 Signs & Symptoms of Anaphylaxis | Anaphylaxis UK

  https://www.anaphylaxis.org.uk/fact-sheet/anaphylaxis-signs-and-symptoms/

  In most cases of anaphylaxis there is a trigger, such as a food, drug or insect sting. But anaphylaxis can also happen in people who have a very rare condition called mastocytosis. […] Mastocytosis is caused by too many mast cells (a type of blood cell that forms part of the immune system) collecting in the tissues of the body. These are the main cells that release histamine and other chemicals that cause allergic symptoms.

• #79 Anaphylaxis DDx • LITFL • CCC Differential Diagnosis

  https://litfl.com/anaphylaxis-ddx/

  Anaphylaxis is a severe, life-threatening, generalised or systemic hypersensitivity reaction. It is characterised by rapidly developing life-threatening airway (pharyngeal or laryngeal edema) and/or breathing (bronchospasm and tachypnea) and/or circulation (hypotension and tachycardia) problems usually associated with skin and mucosal changes. […] Common causes of Anaphylaxis include insect stings (most commonly honeybee, ants, wasps), foods (most commonly peanuts, tree nuts, and seafood in adults; eggs, cows milk, dairy products, seeds, and fruit in children), medications (most commonly antibiotics, non-steroidal anti-inflammatory drugs, contrast-induced anaphylactoid reactions, immunotherapy), and unidentified causes (no cause found, more than 50% of cases). […] Uncommon causes include physical triggers (exercise, heat, cold, UV light), biological fluids (transfusions, immunoglobulin, antivenoms, semen), latex, tick bites, hormonal changes (breastfeeding, menstrual factors), dialysis membranes (haemodialysis-associated anaphylaxis), hydatid cyst rupture, aeroallergens (domestic/laboratory animals, pollen), food additives (monosodium glutamate, metabisulfite, preservatives, colours, natural food chemicals), and topical medications (antiseptics).

• #80 Anaphylaxis DDx • LITFL • CCC Differential Diagnosis

  https://litfl.com/anaphylaxis-ddx/

  Anaphylaxis is a severe, life-threatening, generalised or systemic hypersensitivity reaction. It is characterised by rapidly developing life-threatening airway (pharyngeal or laryngeal edema) and/or breathing (bronchospasm and tachypnea) and/or circulation (hypotension and tachycardia) problems usually associated with skin and mucosal changes. […] Common causes of Anaphylaxis include insect stings (most commonly honeybee, ants, wasps), foods (most commonly peanuts, tree nuts, and seafood in adults; eggs, cows milk, dairy products, seeds, and fruit in children), medications (most commonly antibiotics, non-steroidal anti-inflammatory drugs, contrast-induced anaphylactoid reactions, immunotherapy), and unidentified causes (no cause found, more than 50% of cases). […] Uncommon causes include physical triggers (exercise, heat, cold, UV light), biological fluids (transfusions, immunoglobulin, antivenoms, semen), latex, tick bites, hormonal changes (breastfeeding, menstrual factors), dialysis membranes (haemodialysis-associated anaphylaxis), hydatid cyst rupture, aeroallergens (domestic/laboratory animals, pollen), food additives (monosodium glutamate, metabisulfite, preservatives, colours, natural food chemicals), and topical medications (antiseptics).

• #81 Anaphylaxis DDx • LITFL • CCC Differential Diagnosis

  https://litfl.com/anaphylaxis-ddx/

  Anaphylaxis is a severe, life-threatening, generalised or systemic hypersensitivity reaction. It is characterised by rapidly developing life-threatening airway (pharyngeal or laryngeal edema) and/or breathing (bronchospasm and tachypnea) and/or circulation (hypotension and tachycardia) problems usually associated with skin and mucosal changes. […] Common causes of Anaphylaxis include insect stings (most commonly honeybee, ants, wasps), foods (most commonly peanuts, tree nuts, and seafood in adults; eggs, cows milk, dairy products, seeds, and fruit in children), medications (most commonly antibiotics, non-steroidal anti-inflammatory drugs, contrast-induced anaphylactoid reactions, immunotherapy), and unidentified causes (no cause found, more than 50% of cases). […] Uncommon causes include physical triggers (exercise, heat, cold, UV light), biological fluids (transfusions, immunoglobulin, antivenoms, semen), latex, tick bites, hormonal changes (breastfeeding, menstrual factors), dialysis membranes (haemodialysis-associated anaphylaxis), hydatid cyst rupture, aeroallergens (domestic/laboratory animals, pollen), food additives (monosodium glutamate, metabisulfite, preservatives, colours, natural food chemicals), and topical medications (antiseptics).

• #82 Anaphylaxis DDx • LITFL • CCC Differential Diagnosis

  https://litfl.com/anaphylaxis-ddx/

  Anaphylaxis is a severe, life-threatening, generalised or systemic hypersensitivity reaction. It is characterised by rapidly developing life-threatening airway (pharyngeal or laryngeal edema) and/or breathing (bronchospasm and tachypnea) and/or circulation (hypotension and tachycardia) problems usually associated with skin and mucosal changes. […] Common causes of Anaphylaxis include insect stings (most commonly honeybee, ants, wasps), foods (most commonly peanuts, tree nuts, and seafood in adults; eggs, cows milk, dairy products, seeds, and fruit in children), medications (most commonly antibiotics, non-steroidal anti-inflammatory drugs, contrast-induced anaphylactoid reactions, immunotherapy), and unidentified causes (no cause found, more than 50% of cases). […] Uncommon causes include physical triggers (exercise, heat, cold, UV light), biological fluids (transfusions, immunoglobulin, antivenoms, semen), latex, tick bites, hormonal changes (breastfeeding, menstrual factors), dialysis membranes (haemodialysis-associated anaphylaxis), hydatid cyst rupture, aeroallergens (domestic/laboratory animals, pollen), food additives (monosodium glutamate, metabisulfite, preservatives, colours, natural food chemicals), and topical medications (antiseptics).

• #83 Anaphylaxis – Causes, Diagnosis, Treatment and Coping

  https://www.medindia.net/health/conditions/anaphylaxis.htm

  Anaphylaxis is caused by a substance that the body recognizes as a potential danger and over-reacts to respond to it. […] Causes of anaphylaxis can be categorized as follows: […] Certain foods cause a disturbance in the immune system, most often the first time after ingestion. […] Most commonly known medicines that may cause anaphylaxis are penicillin, aspirin and NSAIDs. […] Stings from insects like wasps, bees, fire ants, and kissing bugs may cause anaphylaxis in people who are vulnerable. […] Latex (the liquid that oozes out of plants) from a few plants and is used to manufacture items like hand gloves can trigger anaphylaxis. […] Exercise is also known to trigger anaphylaxis in the vulnerable group. […] Hypersensitivity that is caused by secretion of a hormone called progesterone by the body is called catamenial anaphylaxis.

• #84 7 Surprising Triggers of Anaphylaxis

  https://www.everydayhealth.com/anaphylaxis/surprising-triggers-anaphylaxis-attack/

  Peanuts and shellfish aren’t the only causes of anaphylaxis. Here are some more triggers you should be aware of. The best-known triggers for anaphylaxis, a severe allergic reaction, are foods like peanuts, tree nuts (such as walnuts), eggs, shellfish, and milk. But foods like these are responsible for just 6.7 percent of fatal cases of anaphylaxis, according to a study published in 2014. It may surprise many people to learn that drugs and blood products are the most common causes of anaphylaxis deaths, according to the study. Some other surprising causes of anaphylactic reactions include exercising, eating red meat, or even having your period though these are not nearly as likely to be fatal reactions. Sperm allergy, also called semen allergy, is a rare cause of anaphylaxis but can cause life-threatening symptoms in women who have it during or after intercourse with a man. It seems to be more common in women who have allergic asthma or atopic dermatitis. In some cases, the anaphylactic reaction occurs because the woman’s partner ate something or took a drug that she’s allergic to, which is then transferred through his semen. In other cases, it’s an allergy to seminal plasma protein, a natural component of semen. Some women experience anaphylaxis just before or during their menstrual cycle. Known as catamenial, or cyclic, anaphylaxis, this rare disorder often goes unrecognized. Most patients, and even healthcare providers, aren’t aware of the association between anaphylaxis and the menstrual cycle. In some cases, the culprit is a medication or food consumed around the time of menstruation. At other times, though, no cause can be found. Meat from mammals can cause symptoms of anaphylaxis hours after you eat it, making it difficult to draw a connection between the food and your allergy. With this form of anaphylaxis, you may not experience symptoms until three to six hours later. A bite from a tick called the lone star tick can cause this allergy. As many as 90 to 100 people in the United States die each year because of a severe allergic reaction to an insect sting. Bees, hornets, and wasps including yellow jackets and fire ants are the insects whose stings are most likely to cause a severe anaphylactic reaction. Sometimes, anaphylaxis happens for unknown reasons. A person is sitting there, watching TV, and has an allergic reaction. If you have a sudden and unexplained allergic reaction, your doctor will probably take a complete history and ask a lot of questions, such as: What did you eat or drink? Did you exercise? Did you take medication? But sometimes, you’ll never know what triggered it. This situation baffles doctors and patients, but it’s not uncommon. In fact, 39 percent of people with anaphylaxis may have had a reaction that can’t be explained by a known trigger.

• #85 Anaphylactic Shock: Symptoms, Causes, Risks, Treatments & More

  https://www.healthline.com/health/anaphylactic-shock

  Anaphylaxis results from an overreaction of your immune system to an allergen, or something your body is allergic to. In turn, anaphylaxis can result in anaphylactic shock. […] Common triggers for anaphylaxis include: certain medications, such as penicillin, insect stings, foods such as tree nuts, shellfish, milk, eggs, agents used in immunotherapy, latex. […] Sometimes, people never identify a cause for this reaction. This type of anaphylaxis is called idiopathic. […] Risk factors for severe anaphylaxis and anaphylactic shock include: a previous anaphylactic reaction, allergies or asthma, a family history of anaphylaxis. […] Anaphylactic shock is extremely serious. It can block your airways and prevent you from breathing. It can also stop your heart. This is due to the decrease in blood pressure that prevents the heart from receiving enough oxygen.

• #86 Anaphylaxis: Causes and Risk Factors

  https://www.verywellhealth.com/anaphylaxis-causes-risk-factors-82703

  Anaphylaxis occurs when the immune system regards an otherwise harmless substance as harmful. The immune overreaction triggers the release of histamine and other mediators of the immune response, causing blood vessels to dilate and tissues to swell. […] Allergies and asthma tend to run in families and there is believed to be a genetic predisposition to them. People with allergies to the common triggers of anaphylaxis are more at risk. […] If you previously had an anaphylactic reaction, you are at greater risk of having one again. Future reactions may be even more severe. […] If you have a poorly-controlled cardiovascular disease you are more at risk of death if you have an episode of anaphylaxis.

• #87 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  People who have asthma and who have previously had a severe allergic reaction are most at risk for anaphylaxis. […] Allergic reactions can be unpredictable. Even if you dont experience severe symptoms the first time, the second allergic reaction could be life-threatening. […] Severe anaphylaxis is potentially life-threatening, especially in people with underlying medical conditions like heart disease or lung disease (especially asthma).

• #88 Too Much of An Allergy-Related Gene Makes Anaphylaxis Worse | Blog

  https://www.bernsteinallergyresearch.com/clinic/blog/2020/12/15/too-much-of-an-allergy-related-gene-makes-anaphylaxis-worse/

  Anaphylaxis is a serious and life-threatening allergic reaction and can occur within minutes after you are exposed to something you are allergic to. […] The most common substances that trigger Anaphylaxis are insect stings, medications, and foods. […] A study shows that individuals with HaT have increased risk of experiencing anaphylaxis compared to those people without HaT. […] Anaphylaxis is the most severe form of an allergic reaction. […] If you experience anaphylaxis once, the next experience could be more severe.

• #89 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  People who have asthma and who have previously had a severe allergic reaction are most at risk for anaphylaxis. […] Allergic reactions can be unpredictable. Even if you dont experience severe symptoms the first time, the second allergic reaction could be life-threatening. […] Severe anaphylaxis is potentially life-threatening, especially in people with underlying medical conditions like heart disease or lung disease (especially asthma).

• #90 Anaphylaxis | Causes, Symptoms & Treatment | ACAAI Public Website

  https://acaai.org/allergies/symptoms/anaphylaxis/

  Anaphylaxis is a rare but severe allergic reaction. It can occur suddenly, can worsen quickly and can be deadly. […] This severe reaction happens when an over-release of chemicals puts the person into shock. Allergies to food, insect stings, medications and latex are most frequently associated with anaphylaxis. […] If you have a history of allergies and/or asthma and have previously had a severe reaction, you are at greater risk for anaphylaxis. […] The most common triggers are: Food: including peanuts, tree nuts such as cashews and pistachio, fish, shellfish, cow’s milk, eggs and sesame. […] Latex: found in disposable gloves, intravenous tubes, syringes, adhesive tapes and catheters. […] Medication: including penicillin and other antibiotics, aspirin and non-steroidal anti-inflammatory drugs such as ibuprofen, and medications used for anesthesia. […] Insect sting: with bees, wasps, hornets, yellow jackets and fire ants being the most likely to trigger anaphylaxis.

• #91

  https://chestercountyallergy.com/allergy-education/anaphylaxis/causes-of-anaphylaxis/

  Causes of Anaphylaxis […] Peanuts, tree nuts (walnuts, cashews, etc.), shellfish, fish, milk, and eggs commonly cause anaphylactic reactions. Only a trace amount of a problem food can cause a reaction in some individuals. […] In the United States, food-induced anaphylaxis is believed to cause about 30,000 trips to the emergency room and between 150 to 200 deaths each year. Individuals who are allergic to foods and have asthma are believed to be at a higher risk for developing an anaphylactic reaction. […] A study of 32 cases of fatal food-allergy induced anaphylaxis showed that adolescents who have peanut and tree nut allergy and asthma, and who dont have quick access to epinephrine during a reaction, are at highest risk for a fatal reaction. […] Anaphylactic reactions to medication will typically occur within an hour after taking the drug; however, reactions may occur several hours later. It is estimated that up to 10 percent of the population may be at risk for allergic reactions to medications. […] According to literature from The American Academy of Allergy, Asthma Immunology, The chances of developing an allergic reaction may be increased if the drug is given frequently, in large doses, or by injection rather than by pill. […] Honeybees, bumblebees, yellow jackets, hornets, wasps, fire ants, and harvester ants are the most common causes of insect stings in the United States. […] Latex allergy is most commonly diagnosed in individuals who are exposed to latex frequently, such as those employed in the health care or rubber industry fields and children with spina bifida and other congenital diseases requiring multiple surgeries. […] Food-dependent, exercise-induced anaphylaxis is very rare and occurs only when an individual eats a specific food and exercises within three to four hours after eating. […] Idiopathic anaphylaxis is a severe reaction in which no cause can be determined.

• #92 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  People who have asthma and who have previously had a severe allergic reaction are most at risk for anaphylaxis. […] Allergic reactions can be unpredictable. Even if you dont experience severe symptoms the first time, the second allergic reaction could be life-threatening. […] Severe anaphylaxis is potentially life-threatening, especially in people with underlying medical conditions like heart disease or lung disease (especially asthma).

• #93 Anaphylaxis: Causes and Risk Factors

  https://www.verywellhealth.com/anaphylaxis-causes-risk-factors-82703

  Anaphylaxis occurs when the immune system regards an otherwise harmless substance as harmful. The immune overreaction triggers the release of histamine and other mediators of the immune response, causing blood vessels to dilate and tissues to swell. […] Allergies and asthma tend to run in families and there is believed to be a genetic predisposition to them. People with allergies to the common triggers of anaphylaxis are more at risk. […] If you previously had an anaphylactic reaction, you are at greater risk of having one again. Future reactions may be even more severe. […] If you have a poorly-controlled cardiovascular disease you are more at risk of death if you have an episode of anaphylaxis.

• #94 Anaphylactic Shock: Symptoms, Causes, Risks, Treatments & More

  https://www.healthline.com/health/anaphylactic-shock

  Anaphylactic shock can also permanently worsen symptoms in people with multiple sclerosis. […] The first step for treating anaphylactic shock will likely be injecting epinephrine (adrenaline) immediately. This can reduce the severity of the allergic reaction. […] Anaphylactic shock can be extremely dangerous, even fatal. Its an immediate medical emergency. Recovery will depend on how quickly you get help.

• #95 Anaphylaxis: Causes and Risk Factors

  https://www.verywellhealth.com/anaphylaxis-causes-risk-factors-82703

  Anaphylaxis occurs when the immune system regards an otherwise harmless substance as harmful. The immune overreaction triggers the release of histamine and other mediators of the immune response, causing blood vessels to dilate and tissues to swell. […] Allergies and asthma tend to run in families and there is believed to be a genetic predisposition to them. People with allergies to the common triggers of anaphylaxis are more at risk. […] If you previously had an anaphylactic reaction, you are at greater risk of having one again. Future reactions may be even more severe. […] If you have a poorly-controlled cardiovascular disease you are more at risk of death if you have an episode of anaphylaxis.

• #96 Anaphylaxis Allergic Reactions – What You Need to Know

  https://www.advancedentdenver.com/blog/anaphylaxis-causes-and-risks/

  Medication allergies are another common cause of anaphylactic reactions for patients of all ages. […] Latex is a natural rubber product that has been used in many items since the 1980s. […] A rare cause of anaphylaxis called exercise-induced anaphylaxis (EIA) can result from physical activity. […] Another rare allergy that can cause anaphylaxis is dust mites, often as a result of eating foods that were contaminated with dust mite particles. […] A rare type of anaphylaxis can happen to people who were bitten by a tick that recently fed on blood from farm animals. […] If you’ve previously suffered from anaphylaxis before, your risk of having this serious reaction increases. […] People who already have seasonal or year-round allergies are at increased risk of experiencing anaphylaxis, as are patients who have asthma. […] Allergies tend to run in the family and there is believed to be a genetic predisposition to allergies and asthma alike. […] If you have a cardiovascular disease that is not under control you may be at a higher risk of death due to anaphylaxis.

• #97 What Causes Anaphylaxis? | Chacko Allergy

  https://atlantaallergydoctor.com/blog/what-causes-anaphylaxis/

  Anaphylaxis causes for Atlanta patients […] The triggers of anaphylaxis are wide-ranging and require an allergy doctor to accurately diagnose. A public survey looking at the causes of anaphylaxis found the three most common triggers to be: medications (34%), foods (31%) and insect stings (20%). However, among infants and young children, food is the most likely cause of a severe allergic reaction. In rarer circumstances, a condition called idiopathic anaphylaxis means doctors are unable to identify the cause. […] Additionally, there may be some cofactors that increase the likelihood of an anaphylactic reaction. These cofactors are more common in older people and include exercise, stress and infections. […] Anaphylaxis is an extreme overreaction by the immune system to a perceived threat. Even the smallest amount of a substance in ones body can trigger the release of chemicals that cause blood vessels to swell.

• #98 Food allergy and intolerance | Better Health Channel

  https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/food-allergy-and-intolerance

  A food allergy occurs when the immune system reacts to a food which is usually harmless. […] Food intolerance does not involve the immune system and does not cause severe allergic reactions (anaphylaxis). […] Anaphylaxis is a severe allergic reaction that needs urgent medical attention. Foods (such as peanuts, tree nuts, seafood, wheat, milk and eggs), insect bites and stings and some medicines are the most common allergens that cause anaphylaxis. […] Peanuts, tree nuts, eggs, cows milk, wheat, sesame, fish, shellfish and soy cause the majority of food allergic reactions. […] Several factors can influence the severity of anaphylaxis, including exercise, heat, alcohol, the amount of food eaten, and how food is prepared and consumed.

• #99 What Causes Anaphylaxis? | Chacko Allergy

  https://atlantaallergydoctor.com/blog/what-causes-anaphylaxis/

  Anaphylaxis causes for Atlanta patients […] The triggers of anaphylaxis are wide-ranging and require an allergy doctor to accurately diagnose. A public survey looking at the causes of anaphylaxis found the three most common triggers to be: medications (34%), foods (31%) and insect stings (20%). However, among infants and young children, food is the most likely cause of a severe allergic reaction. In rarer circumstances, a condition called idiopathic anaphylaxis means doctors are unable to identify the cause. […] Additionally, there may be some cofactors that increase the likelihood of an anaphylactic reaction. These cofactors are more common in older people and include exercise, stress and infections. […] Anaphylaxis is an extreme overreaction by the immune system to a perceived threat. Even the smallest amount of a substance in ones body can trigger the release of chemicals that cause blood vessels to swell.

• #100 Anaphylaxis (Anaphylactic Reaction): Symptoms, Causes, Treatment

  https://www.webmd.com/allergies/anaphylaxis

  Anaphylaxis happens when you have an antibody, something that usually fights infection, that reacts too much to something that should be harmless, like food. It might not happen the first time you come in contact with the trigger, but it can get worse over time. […] In children, the most common cause of anaphylaxis is food. For adults, medications more often cause it. […] Common food triggers for children are: Peanuts, Shellfish, Fish, Milk, Eggs, Soy, Wheat. […] Common food triggers for adults are: Shellfish, Tree nuts (walnuts, hazelnuts, cashews, pistachios, pine nuts, and almonds), Peanuts. […] Common medication triggers are: Penicillin (more often following a shot rather than a pill), Muscle relaxants like the ones used for anesthesia, Aspirin, ibuprofen, and other NSAIDs (nonsteroidal anti-inflammatory drugs), Anti-seizure medications.

• #101 Patient education: Anaphylaxis symptoms and diagnosis (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/anaphylaxis-symptoms-and-diagnosis-beyond-the-basics

  Anaphylaxis is a potentially deadly allergic reaction that is rapid in onset. It is most often caused or triggered by foods, medications, and insect stings. There are many other possible triggers. […] Common anaphylaxis triggers can include: […] Foods. In children, hen’s eggs, cow’s milk, peanuts, tree nuts, fish, wheat, and soy are the most common food triggers. In teens and adults, peanuts, tree nuts, fish, and crustaceans (shellfish such as shrimp) are the most common triggers. Any food, including fruits, vegetables, seeds, and some spices and food additives, can cause anaphylaxis. […] Medications, such as antibiotics (penicillins and cephalosporins) and analgesics (aspirin, ibuprofen). […] Venom from insects, including bees, yellowjackets, wasps, hornets, and fire ants. […] IgE-mediated anaphylaxis — In most people, anaphylaxis is caused by the presence of antibodies called „immunoglobulin E” (IgE). In people with allergies, IgE is made in response to substances such as foods, medications, or insect venoms. This IgE then sticks to the outside of mast cells in body tissues and basophils, a type of white blood cell.

• #102 Anaphylaxis Statistics – Allergy & Asthma Network

  https://allergyasthmanetwork.org/anaphylaxis/anaphylaxis-statistics/

  Anaphylaxis is caused by exposure to a trigger or allergen. The most common triggers include: […] In infants, food accounts for 73% of anaphylaxis symptoms. The most common trigger foods are egg, milk, peanut, and banana. Drugs account for 20% of anaphylaxis cases in infants, followed by unknown triggers. […] The fatality rate for an anaphylactic reaction in the United States is about 0.3%.

• #103 Anaphylaxis (Anaphylactic Reaction): Symptoms, Causes, Treatment

  https://www.webmd.com/allergies/anaphylaxis

  Anaphylaxis happens when you have an antibody, something that usually fights infection, that reacts too much to something that should be harmless, like food. It might not happen the first time you come in contact with the trigger, but it can get worse over time. […] In children, the most common cause of anaphylaxis is food. For adults, medications more often cause it. […] Common food triggers for children are: Peanuts, Shellfish, Fish, Milk, Eggs, Soy, Wheat. […] Common food triggers for adults are: Shellfish, Tree nuts (walnuts, hazelnuts, cashews, pistachios, pine nuts, and almonds), Peanuts. […] Common medication triggers are: Penicillin (more often following a shot rather than a pill), Muscle relaxants like the ones used for anesthesia, Aspirin, ibuprofen, and other NSAIDs (nonsteroidal anti-inflammatory drugs), Anti-seizure medications.

• #104 A survey of anaphylaxis etiology and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6352571/

  Identifying the causes of anaphylaxis which is an acute, potentially fatal systemic reaction is very important in every community. […] We sought to determine the most common triggers of anaphylaxis, clinical manifestations and treatment strategies in Mashhad, northeast of Iran. […] We used a combination of patients clinical history and allergy diagnostic testing including radioallergosorbant test and skin prick test in order to determine the etiology of anaphylaxis. […] The triggers included: foods, 61.4%; drugs, 15.7%; hymenoptera venom, 8.6%; idiopathic, 5.7%; immunotherapy, 4.3% and other etiologies: 5.7%. […] The most common cause of anaphylaxis during childhood (less than 19 years old) was food. […] In our study, in adults (over 20 years old), the most common causes of anaphylaxis were foods, medicines, hymenoptera venom, idiopathic and miscellaneous causes, respectively.

• #105 Patient education: Anaphylaxis symptoms and diagnosis (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/anaphylaxis-symptoms-and-diagnosis-beyond-the-basics

  Anaphylaxis is a potentially deadly allergic reaction that is rapid in onset. It is most often caused or triggered by foods, medications, and insect stings. There are many other possible triggers. […] Common anaphylaxis triggers can include: […] Foods. In children, hen’s eggs, cow’s milk, peanuts, tree nuts, fish, wheat, and soy are the most common food triggers. In teens and adults, peanuts, tree nuts, fish, and crustaceans (shellfish such as shrimp) are the most common triggers. Any food, including fruits, vegetables, seeds, and some spices and food additives, can cause anaphylaxis. […] Medications, such as antibiotics (penicillins and cephalosporins) and analgesics (aspirin, ibuprofen). […] Venom from insects, including bees, yellowjackets, wasps, hornets, and fire ants. […] IgE-mediated anaphylaxis — In most people, anaphylaxis is caused by the presence of antibodies called „immunoglobulin E” (IgE). In people with allergies, IgE is made in response to substances such as foods, medications, or insect venoms. This IgE then sticks to the outside of mast cells in body tissues and basophils, a type of white blood cell.

• #106 Anaphylaxis (Anaphylactic Reaction): Symptoms, Causes, Treatment

  https://www.webmd.com/allergies/anaphylaxis

  Anaphylaxis happens when you have an antibody, something that usually fights infection, that reacts too much to something that should be harmless, like food. It might not happen the first time you come in contact with the trigger, but it can get worse over time. […] In children, the most common cause of anaphylaxis is food. For adults, medications more often cause it. […] Common food triggers for children are: Peanuts, Shellfish, Fish, Milk, Eggs, Soy, Wheat. […] Common food triggers for adults are: Shellfish, Tree nuts (walnuts, hazelnuts, cashews, pistachios, pine nuts, and almonds), Peanuts. […] Common medication triggers are: Penicillin (more often following a shot rather than a pill), Muscle relaxants like the ones used for anesthesia, Aspirin, ibuprofen, and other NSAIDs (nonsteroidal anti-inflammatory drugs), Anti-seizure medications.

• #107 Anaphylaxis | Causes, Symptoms & Treatment | ACAAI Public Website

  https://acaai.org/allergies/symptoms/anaphylaxis/

  Anaphylaxis is a rare but severe allergic reaction. It can occur suddenly, can worsen quickly and can be deadly. […] This severe reaction happens when an over-release of chemicals puts the person into shock. Allergies to food, insect stings, medications and latex are most frequently associated with anaphylaxis. […] If you have a history of allergies and/or asthma and have previously had a severe reaction, you are at greater risk for anaphylaxis. […] The most common triggers are: Food: including peanuts, tree nuts such as cashews and pistachio, fish, shellfish, cow’s milk, eggs and sesame. […] Latex: found in disposable gloves, intravenous tubes, syringes, adhesive tapes and catheters. […] Medication: including penicillin and other antibiotics, aspirin and non-steroidal anti-inflammatory drugs such as ibuprofen, and medications used for anesthesia. […] Insect sting: with bees, wasps, hornets, yellow jackets and fire ants being the most likely to trigger anaphylaxis.

• #108 Anaphylaxis: Causes, Symptoms and Treatment | Allergy Insider

  https://www.thermofisher.com/allergy/us/en/living-with-allergies/symptom-management/anaphylaxis.html

  Anaphylaxis is a severe and potentially life-threatening allergic reaction. Like other allergy symptoms, its triggered when the immune system overreacts and releases histamine (among other chemicals) in response to an allergen, such as peanuts, shellfish, latex, insect venom, dust mites, and countless more. […] While there may be other causes of anaphylaxis, such as exercise, allergens are the main culprits. Among them, food allergens are the most frequent triggers of anaphylaxis in children, and insect venom and various drug allergies are the most prevalent offenders in adults. Additionally, according to an article published in The Journal of Allergy and Clinical Immunology, drugs are the most common reported cause of fatal anaphylaxis in countries such as Australia, New Zealand, the United Kingdom, Brazil, and the United States.

• #109 Anaphylaxis – Wikipedia

  https://en.wikipedia.org/wiki/Anaphylaxis

  Common causes include allergies to insect bites and stings, allergies to foods including nuts, milk, fish, shellfish, eggs and some fresh fruits or dried fruits; allergies to sulfites a class of food preservatives and a byproduct in some fermented foods like vinegar; allergies to medications including some antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin; allergy to general anaesthetic (used to make people sleep during surgery); allergy to contrast agents dyes used in some medical tests to help certain areas of the body show up better on scans; allergy to latex a type of rubber found in some rubber gloves and condoms.[6][1] […] Anaphylaxis can occur in response to almost any foreign substance.[20] Common triggers include venom from insect bites or stings, foods, and medication.[10][21] Foods are the most common trigger in children and young adults, while medications and insect bites and stings are more common in older adults.[3] […] The cause remains unknown in 32-50% of cases, referred to as „idiopathic anaphylaxis.”[28] Six vaccines (MMR, varicella, influenza, hepatitis B, tetanus, meningococcal) are recognized as a cause for anaphylaxis, and HPV may cause anaphylaxis as well.[29]

• #110 What is Anaphylaxis? Causes, Symptoms, Treatments & More | CAAC

  https://www.carolinaasthma.com/blog/what-is-anaphylaxis/

  Most have heard of allergic reactions, but few understand the characteristics of the most serious and life-threatening allergic reaction known as anaphylaxis. […] Anaphylaxis, as well as allergies in general, occurs when the body overreacts to an allergen. […] When the body is exposed to an allergen, it responds by producing histamine and other chemicals causing your blood vessels to dilate. This allows more fluid to enter your tissues and causes swelling. During anaphylaxis, these chemicals are released throughout the whole body and can cause low blood pressure, hives, and difficulty breathing. […] Food allergies are the most common cause of anaphylaxis. Some prevalent triggers include: shellfish, nuts, milk, eggs, fish, and some fruits. […] Insect stings, especially those from bees or wasps, can also trigger anaphylaxis.

• #111 Anaphylaxis: Causes, Symptoms & Diagnosis

  https://www.healthline.com/health/anaphylaxis

  For some people with severe allergies, exposure to their allergen can result in a life-threatening reaction called anaphylaxis. Anaphylaxis is a severe allergic reaction to venom, food, or medication. Most cases are caused by a bee sting or eating foods that are known to cause allergies, such as peanuts or tree nuts. […] Common causes of anaphylaxis include medication, peanuts, tree nuts, insect stings, fish, shellfish, and milk. Other causes may include exercise and latex. […] In most cases, the body doesnt react to the antibodies being released. However, in the case of anaphylaxis, the immune system overreacts in a way that causes a full-body allergic reaction.

• #112 Anaphylaxis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/8619-anaphylaxis

  People who have asthma and who have previously had a severe allergic reaction are most at risk for anaphylaxis. […] Allergic reactions can be unpredictable. Even if you dont experience severe symptoms the first time, the second allergic reaction could be life-threatening. […] Severe anaphylaxis is potentially life-threatening, especially in people with underlying medical conditions like heart disease or lung disease (especially asthma).

• #113 What Causes Anaphylaxis? | Chacko Allergy

  https://atlantaallergydoctor.com/blog/what-causes-anaphylaxis/

  Anaphylaxis causes for Atlanta patients […] The triggers of anaphylaxis are wide-ranging and require an allergy doctor to accurately diagnose. A public survey looking at the causes of anaphylaxis found the three most common triggers to be: medications (34%), foods (31%) and insect stings (20%). However, among infants and young children, food is the most likely cause of a severe allergic reaction. In rarer circumstances, a condition called idiopathic anaphylaxis means doctors are unable to identify the cause. […] Additionally, there may be some cofactors that increase the likelihood of an anaphylactic reaction. These cofactors are more common in older people and include exercise, stress and infections. […] Anaphylaxis is an extreme overreaction by the immune system to a perceived threat. Even the smallest amount of a substance in ones body can trigger the release of chemicals that cause blood vessels to swell.

• #114 Anaphylaxis

  https://www.aaaai.org/conditions-treatments/allergies/anaphylaxis

  Anaphylaxis (an-a-fi-LAK-sis) is a serious, life-threatening allergic reaction. The most common anaphylactic reactions are to foods, insect stings, medications and latex. […] If you are allergic to a substance, your immune system overreacts to this allergen by releasing chemicals that cause allergy symptoms. […] Certain people are more at risk of anaphylaxis. If you have allergies or asthma and have a family history of anaphylaxis, your risk is higher. […] To diagnose your risk of anaphylaxis or to determine whether previous symptoms were anaphylaxis-related, your allergist / immunologist will conduct a thorough investigation of all potential causes. […] If you are at risk of anaphylaxis, carry epinephrine (adrenaline). They contain a prescribed single dose of medication that is injected into the thigh or intranasally during an anaphylactic emergency. […] Important Reminder If you think you are having an anaphylactic reaction, use your epinephrine and call 911 immediately so you can be transported to the nearest emergency department for evaluation, monitoring and any further treatment by healthcare professionals. Your life depends on this.

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