Materiały źródłowe

• #1 Toxic hepatitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/toxic-hepatitis/symptoms-causes/syc-20352202

  Toxic hepatitis occurs when your liver develops inflammation because of exposure to a toxic substance. Toxic hepatitis may also develop when you take too much of a prescription or over-the-counter medication. […] Because it’s not possible to know how you’ll react to a particular medication, toxic hepatitis can’t always be prevented. But you may reduce your risk of liver problems if you: […] Limit medications. Take prescription and nonprescription drugs only when absolutely necessary. Investigate nondrug options for common problems such as high blood pressure, high cholesterol and arthritis pain. […] Take medications only as directed. Follow the directions exactly for any drug you take. Don’t exceed the recommended amount, even if your symptoms don’t seem to improve. Because the effects of over-the-counter pain relievers sometimes wear off quickly, it’s easy to take too much.

• #2 Hepatitis: What It Is, Symptoms, Transmission & Treatments

  https://my.clevelandclinic.org/health/diseases/hepatitis

  Toxic hepatitis can be acute or chronic. […] You can help prevent hepatitis by: […] Using medications as directed. If you have a substance use disorder, treatment can help prevent toxic hepatitis.

• #3 Drugs and Chemicals That Cause Toxic Liver Disease

  https://www.webmd.com/fatty-liver-disease/toxic-liver-disease

  You cant always know ahead of time what drugs or chemicals could cause toxic liver disease. Here are some ways you may be able to prevent it: […] Only take the drugs you need. Take them only as your doctor instructs. Follow package directions for the recommended dosage. […] Dont take supplements that contain herbs that could be toxic to your liver. Check the labels of any natural treatment before you take it, and run it by your doctor or pharmacist. […] Avoid alcohol if you’re taking acetaminophen. The exact amounts of alcohol and acetaminophen that can lead to liver damage aren’t known. It’s safest to avoid mixing the two. […] Follow safety rules if you use any chemicals or solvents at work. Avoid or limit your exposure if you can. […] Lock up all drugs or chemicals in your home so children dont eat them. They can get liver toxicity too. They are more at risk of liver toxicity because of their small size.

• #4 Toxic hepatitis | Beacon Health System

  https://www.beaconhealthsystem.org/library/diseases-and-conditions/toxic-hepatitis?content_id=CON-20166943

  Because it’s not possible to know how you’ll react to a particular medication, toxic hepatitis can’t always be prevented. But you may reduce your risk of liver problems if you: […] Limit medications. Take prescription and nonprescription drugs only when absolutely necessary. Investigate nondrug options for common problems such as high blood pressure, high cholesterol and arthritis pain. […] Take medications only as directed. Follow the directions exactly for any drug you take. Don’t exceed the recommended amount, even if your symptoms don’t seem to improve. Because the effects of over-the-counter pain relievers sometimes wear off quickly, it’s easy to take too much. […] Be cautious with herbs and supplements. Don’t assume that a natural product won’t cause harm. Discuss the benefits and risks with your doctor before taking herbs and supplements. The National Institutes of Health maintains the LiverTox website, where you can look up medications and supplements to see if they’re linked to liver damage.

• #5

  https://www.amerikanhastanesi.org/mayo-clinic-care-network/mayo-clinic-health-information-library/diseases-conditions/toxic-hepatitis

  Toxic hepatitis occurs when your liver develops inflammation because of exposure to a toxic substance. Toxic hepatitis may also develop when you take too much of a prescription or over-the-counter medication. […] Because it’s not possible to know how you’ll react to a particular medication, toxic hepatitis can’t always be prevented. But you may reduce your risk of liver problems if you: […] Limit medications. Take prescription and nonprescription drugs only when absolutely necessary. Investigate nondrug options for common problems such as high blood pressure, high cholesterol and arthritis pain. […] Take medications only as directed. Follow the directions exactly for any drug you take. Don’t exceed the recommended amount, even if your symptoms don’t seem to improve. […] Be cautious with herbs and supplements. Don’t assume that a natural product won’t cause harm. Discuss the benefits and risks with your doctor before taking herbs and supplements.

• #6 Drug-induced liver injury: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000226.htm

  Never use more than the recommended dose of over-the-counter medicines containing acetaminophen (Tylenol). […] Do not take these medicines if you drink heavily or regularly. Talk to your provider about safe doses. […] Always tell your provider about all the medicines you take, including over-the-counter drugs and herbal or supplemental preparations. This is very important if you have liver disease. […] Talk to your provider about other medicines you may need to avoid. Your provider can tell you which medicines are safe for you.

• #7 Preventive Strategies in Chronic Liver Disease: Part I. Alcohol, Vaccines, Toxic Medications and Supplements, Diet and Exercise | AAFP

  https://www.aafp.org/pubs/afp/issues/2001/1101/p1555.html

  Chronic liver disease is the 10th leading cause of death in the United States. Preventive care can significantly reduce the progression of liver disease. […] Vaccination is recommended. […] Abstinence is the most important measure in keeping chronic liver disease from progressing to cirrhosis. […] Strong evidence supports vaccination against hepatitis A and B viruses in patients with chronic liver disease. […] All patients with chronic liver disease should be checked for hepatitis A total antibody and hepatitis B surface and core antibodies. […] All medications should be evaluated for toxic effects on the liver. […] If data indicate that a drug may be hepatotoxic, an alternative drug with less or no hepatotoxicity should be sought. […] Patients with chronic liver disease should be asked specifically about the use of alternative therapies. […] Measures that can be effective in preventing the progression of chronic liver disease to cirrhosis are summarized in Table 3.

• #8 Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report | European Journal of Psychiatry

  https://www.elsevier.es/en-revista-european-journal-psychiatry-431-articulo-drug-induced-toxic-hepatitis-associated-with-S0213616317300368

  Toxic hepatitis is an inflammation of the liver that occurs in response to various substances, such as alcohol, drugs and various chemicals. […] Therefore, during long-term treatment with antipsychotics we must pay attention to the impact of drugs on the development of certain physical disturbances. […] Our goal was to pay attention to the risks of prescribing a combination of antipsychotics in order to prevent the development of physical disease in psychiatric patients. […] The prolonged use of antipsychotic drugs in the treatment of schizophrenia increases the incidence of physical comorbidity. […] We consider that it is important to monitor patients for liver damage due to the cumulative toxic effects of combination drug treatment.

• #9 Toxic Hepatitis (Liver Toxicity): Symptoms, Causes & Treatments

  https://my.clevelandclinic.org/health/diseases/17915-toxic-hepatitis

  To help prevent toxic hepatitis: […] Avoid exposure to industrial chemicals that may affect your liver. […] Don’t use recreational drugs like cocaine or marijuana. […] Limit how much alcohol you drink. […] Carefully follow dosage instructions for over-the-counter medications. […] Talk to a healthcare provider before taking any supplements. […] You can help keep your liver healthy by making healthy lifestyle changes.

• #10 Toxic hepatitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/toxic-hepatitis/symptoms-causes/syc-20352202

  Be cautious with herbs and supplements. Don’t assume that a natural product won’t cause harm. Discuss the benefits and risks with your doctor before taking herbs and supplements. The National Institutes of Health maintains the LiverTox website, where you can look up medications and supplements to see if they’re linked to liver damage. […] Don’t mix alcohol and drugs. Alcohol and medications are a bad combination. If you’re taking acetaminophen, don’t drink alcohol. Ask your doctor or pharmacist about the interaction between alcohol and other prescription and nonprescription drugs you use. […] Take precautions with chemicals. If you work with or use hazardous chemicals, take all necessary precautions to protect yourself from exposure. If you do come in contact with a harmful substance, follow the guidelines in your workplace, or call your local emergency services or your local poison control center for help. […] Keep medications and chemicals away from children. Keep all medications and vitamin supplements away from children and in childproof containers so that children can’t accidentally swallow them.

• #11 Hepatitis: Symptoms, Treatment and Prevention |Banner Health

  https://www.bannerhealth.com/services/gastroenterology/treatment/hepatitis

  Toxic hepatitis: Caused by chemicals, poisons or certain medications. […] Avoid alcohol: If you have hepatitis, you shouldnt drink alcohol. It may make your liver damage worse and also keep antiviral medications from working correctly. […] Vaccinations: Vaccinations for hepatitis A and B can protect you and your loved ones from getting infected. […] Steer clear of things that can damage your liver: Certain medications such as acetaminophen (Tylenol) used in high doses or for long periods of time, as well as vitamin A, illegal drugs and toxic chemicals can cause liver damage. Be sure to talk to your doctor about whether your medications are safe for your liver. […] You can take these steps to reduce your risk of being infected with hepatitis: Wash your hands often with soap and water, especially after using the bathroom.

• #12 Living with Hepatitis: How to Stay Healthy | doh

  https://dchealth.dc.gov/service/living-hepatitis-how-stay-healthy

  Get your Hepatitis A and Hepatitis B vaccinations: Youve got one viral infection your liver has to deal with. Prevent other viral infections that are known to harm the liver and are vaccine preventable. […] Eliminate Harmful Chemicals From Your Body: A. ALL alcohol, in any amount, is harmful to your liver. Eliminate all alcohols from your diet. B. ALL illicit drugs are harmful to your liver. Studies have shown that the use of marijuana can cause the liver to progress to scarring sooner. It doesnt make any difference on how the drug is used (injecting, smoking, eating, inhaling), they are all harmful to your liver. Eliminate all illegal drug use. Talk with your provider or a counselor to identify ways to help you stop the use of any illegal drugs. C. Decrease polluted air that you breathe, such as: 1) Second-hand cigarette smoke 2) Car exhaust 3) Agricultural pesticides 4) Smog

• #13 Toxic hepatitis | Beacon Health System

  https://www.beaconhealthsystem.org/library/diseases-and-conditions/toxic-hepatitis?content_id=CON-20166943

  Don’t mix alcohol and drugs. Alcohol and medications are a bad combination. If you’re taking acetaminophen, don’t drink alcohol. Ask your doctor or pharmacist about the interaction between alcohol and other prescription and nonprescription drugs you use. […] Take precautions with chemicals. If you work with or use hazardous chemicals, take all necessary precautions to protect yourself from exposure. If you do come in contact with a harmful substance, follow the guidelines in your workplace, or call your local emergency services or your local poison control center for help. […] Keep medications and chemicals away from children. Keep all medications and vitamin supplements away from children and in childproof containers so that children can’t accidentally swallow them.

• #14 Toxic Hepatitis | Health & Human Services

  https://hhs.iowa.gov/epi-manual-guide-surveillance-investigation-and-reporting/environmental-disease/toxic-hepatitis

  E. Prevention of Exposure […] People who work with or use hazardous chemicals should be trained regarding the risks, and should take all necessary precautions to protect themselves from exposure. Safety Data Sheets (SDS formerly called Material Safety Data Sheets or MSDS) can provide information about personal protective equipment (PPE) requirements, first aid, and exposure risks. If workers do come in contact with a harmful substance, they should follow the guidelines established in their workplace, and call the local emergency services or poison control center for help as needed. […] The National Institute of Occupational Safety and Health (NIOSH) Pocket Guide to Chemical Hazards (http://www.cdc.gov/niosh/npg/default.html) is intended as a source of general industrial hygiene information on several hundred chemicals/classes for workers, employers, and occupational health professionals. The NPG does not contain an analysis of all pertinent data; rather it presents key information and data in abbreviated or tabular form for chemicals or substance groupings (e.g. cyanides, fluorides, manganese compounds) that are found in the work environment. The information found in the NPG should help users recognize and control occupational chemical hazards. […]

• #15 Hepatitis B Foundation: Healthy Liver Tips

  https://www.hepb.org/treatment-and-management/adults-with-hepatitis-b/healthy-liver-tips/

  Get the Hepatitis A vaccine to protect yourself from another virus that attacks the liver. […] Avoid inhaling fumes from paint, paint thinners, glue, household cleaning products, nail polish removers, and other potentially toxic chemicals that could damage your liver. […] Avoid eating raw or undercooked shellfish (e.g. clams, mussels, oysters, scallops) because they could be contaminated with a bacteria called Vibrio vulnificus, which is very toxic to the liver and could cause a lot of damage. […] Check for signs of mold on nuts, maize, corn, groundnut, sorghum, and millet before using these foods. Mold is more likely to be a problem if food is stored in damp conditions and not properly sealed. If there is mold, then the food could be contaminated by aflatoxins, which are a known risk factor for liver cancer.

• #16 Living with Hepatitis: How to Stay Healthy | doh

  https://dchealth.dc.gov/service/living-hepatitis-how-stay-healthy

  Get a Prescription Review: Have your doctor or pharmacist review all your prescribed medications to ensure that none of your medications are toxic for your liver. Ask your provider about alternatives to any medications that may harm your liver. […] Use Over The Counter Medications Properly: Always follow the directions on the package, unless told otherwise by your medical provider. […] Be Careful With Vitamins, Herbs and Mineral Use: A. Some of the Fat Soluble vitamins can build up in your system and be toxic to your liver. Check with your provider before taking more than the daily recommendations. B. Before taking any herbal supplement, research it and make sure that it doesnt have the potential to damage to your liver, such as Kava, Valerian Root and Sassafras. Check with your doctor before adding any herbal supplements to your diet. C. The liver has to store all the excess iron that you take in during a day. Its important not to eat more iron in a 24 hour day than what your body actually uses. Extra iron stored in the liver can cause your liver to begin scarring sooner. Talk with a dietician or your doctor to find out how much iron you should eat in a day.

• #17 Drugs and Chemicals That Cause Toxic Liver Disease

  https://www.webmd.com/fatty-liver-disease/toxic-liver-disease

  Work on weight loss. Losing about 5% of your body weight could make a difference in reducing fat in your liver. A 7% to 10% loss of body weight could decrease inflammation around your liver. It may also reverse fibrosis, or scarring, of the liver. Aim to lose about 1 to 2 pounds a week until you reach your ideal weight. […] Make exercise a priority. Intense aerobic exercise is shown to decrease inflammation and fat in the liver. But always check with your doctor before you start a new exercise plan. […] Eat a healthy diet. Studies show adopting a nutrition plan that includes fruits and veggies, whole grains, legumes, and nuts could decrease fat in the liver. Swapping olive oil for butter also helps lessen fatty liver, as well as eating more fish and lean poultry. […] Dont skip that morning coffee. Some studies show that those who drank two cups of coffee daily had less liver fibrosis.

• #18 Living with Hepatitis: How to Stay Healthy | doh

  https://dchealth.dc.gov/service/living-hepatitis-how-stay-healthy

  Modify Your Diet: A. Decrease the amount of fatty foods and cholesterol that you eat. Extra fat stored in the liver can cause a liver to begin scarring sooner. B. Increase the amount of actual water that you drink during a 24 hour day. Water helps flush the chemicals and poisons out of your body. To find out how much water you should drink in a 24 hour period: take your body weight in pounds and divide it by 2. This equals how many ounces of water you should drink each day. […] Light Daily Exercise: Light daily exercise such as walking will help boost your immune system as well as help decrease excess fat stored in your liver. Talk to your provider about what the best form of exercise would be for you. […] Symptoms That Need to be Reported to Your Provider: A. White or Gray colored stools B. Coca-Cola colored urine C. Increased amount of time before a cut or wound stops bleeding D. The white part of your eyes turning yellow.

• #19 Toxic hepatitis

  https://synevo.ge/en/toxic-hepatitis/

  Prevention: […] – Only take necessary medications, in the dosage recommended by your doctor. […] – Avoid taking biological and nutritional supplements. […] – Stopping or limiting alcohol consumption. […] – Taking maximum precautions when working with toxins and solvents. […] – Maintaining a healthy diet and lifestyle. […] […] […] There is evidence that 2 cups of coffee a day can prevent liver fibrosis.

• #20 Liver Disease Prevention | Stanford Health Care

  https://stanfordhealthcare.org/medical-treatments/l/liver-disease-prevention/procedure.html

  Using a team approach, our liver disease specialists work side by side to deliver comprehensive preventive services. […] Liver disease prevention at Stanford includes: […] Vaccines: Some forms of liver disease, such as hepatitis B, are preventable with the help of a vaccine. If you are at risk for hepatitis B and have not been diagnosed, the vaccine prevents you from getting it.

• #21 Viral Hepatitis Basics | Viral Hepatitis | CDC

  https://www.cdc.gov/hepatitis/about/index.html

  Vaccines can prevent hepatitis A and hepatitis B and medications can cure hepatitis C. […] The best way to prevent hepatitis A and hepatitis B is by getting vaccinated. You need to get all the shots in the series to be fully protected. […] The best way to prevent contracting hepatitis C is to avoid behaviors that can spread the disease, like sharing or reusing needles or other personal items that might come into contact with blood that is infected with the virus.

• #22 Hepatitis C – Arkansas Department of Health

  https://healthy.arkansas.gov/programs-services/diseases-conditions/infectious-disease/hepatitis-c/

  Hepatitis C can be either acute or chronic. […] There is no vaccine for hepatitis C, but there are effective methods to prevent being infected. The best way to prevent hepatitis C is by avoiding behaviors that can spread the disease, especially injection drug use, and by using precautions when exposed to blood. […] Arkansas Act 598 of 2021 requires that healthcare providers in Arkansas must offer hepatitis C testing to all pregnant women. […] Hepatitis C is treatable with a short course of direct-acting antiviral medication. […] In addition to treatment with direct-acting antivirals, there are several recommendations that most patients with hepatitis C should follow. They include: Talk with your healthcare provider about HIV screening. Get vaccinated against hepatitis A and hepatitis B. Avoid consuming alcohol. […] If you have been diagnosed with hepatitis C: Do not share anything that may become contaminated with blood. This includes needles, syringes, toothbrushes, razors, and other items. […] Hepatitis C is a reportable disease in Arkansas.

• #23 Know The ABC’s of Hepatitis Prevention – NFID

  https://www.nfid.org/know-the-abcs-of-hepatitis-prevention/

  Hepatitis Awareness Month, held each May in the US, is a month-long observance designed to raise awareness of viral hepatitis prevention, diagnosis, and treatment and to encourage at-risk populations to get tested and ensure they are up-to-date with recommended vaccines. […] Fortunately, effective vaccines are available to help prevent hepatitis A and hepatitis B. […] Vaccination can prevent HBV infection and related complications. In the US, hepatitis B vaccination is given within 24 hours of birth, as well as to children and adolescents who have not been vaccinated previously and to adults at risk for HBV infection. […] There is currently no vaccine available to help prevent HCV. The best way to prevent the disease is to avoid behaviors that cause its spread, particularly injecting recreational drugs.

• #24 Hepatitis B Prevention – Viral Hepatitis and Liver Disease

  https://www.hepatitis.va.gov/hbv/patient/prevent.asp

  Hepatitis B vaccine is available to prevent HBV infection. […] Vaccination for hepatitis B is given as an injection in the upper arm and requires more than one dose. […] You may need the vaccination against hepatitis B if any of these are true for you: are age 19 to 59 years and have not previously been vaccinated against hepatitis B virus; are at increased risk for infection with hepatitis B virus; have chronic liver disease; seek protection from hepatitis B infection. […] Increased risk includes: household contacts of HBV-infected persons; sexual contacts of HBV-infected persons; persons who have shared needles with HBV-infected persons; current or previous injection-drug use; sexually active persons with more than one sex partner; men who have sex with men; persons seeking evaluation or treatment for a sexually transmitted infection; persons with HIV infection; persons with diabetes who are under the age of 60; health care personnel, public safety workers, and other persons with risk for exposure to blood or other potentially infectious body fluids; travelers to countries with high or intermediate prevalence of HBV infection.

• #25 Hepatitis A: Symptoms, Causes, Treatment, and Prevention

  https://www.healthline.com/health/hepatitis-a

  The No. 1 way to avoid getting hepatitis A is by getting the hepatitis A vaccine. This vaccine is given in a series of two injections, 6 to 12 months apart. […] To limit your chance of contracting hepatitis A, you should also: thoroughly wash your hands with soap and warm water before eating or drinking, and after using the restroom; drink bottled water rather than local water in developing countries, or in countries where there’s a high risk of contracting hepatitis A; dine at established, reputable restaurants, rather than from street vendors; avoid eating peeled or raw fruit and vegetables in an area with low sanitation or hygienic standards.

• #26 Antiretroviral Associated Adverse Effects and Management Recommendations for Hepatic Events | NIH

  https://clinicalinfo.hiv.gov/en/guidelines/pediatric-arv/hepatic-events-full

  Most ARV drugs have been associated with hepatitis, but a strong association exists between hepatitis and the use of NVP and EFV. […] Prevention: Avoid concomitant use of hepatotoxic medications. […] In patients with elevated levels of hepatic enzymes (5 times to 10 times ULN) or chronic liver disease, most clinicians would avoid NVP.

• #27 Hepatitis B or raised liver enzymes predict liver toxicity when TB prevention drug is combined with HIV treatment | aidsmap

  https://www.aidsmap.com/news/jun-2018/hepatitis-b-or-raised-liver-enzymes-predict-liver-toxicity-when-tb-prevention-drug

  The investigators warn that in people with hepatitis B taking isoniazid, hepatotoxicity could be an immune reconstitution inflammatory syndrome (IRIS) as a consequence of antiretroviral treatment rather than IPT. Approximately one in five people with HBV and HIV co-infection are likely to experience a hepatitis flare in the first three months after starting antiretroviral treatment. The authors suggest that IPT should be introduced after the risk of HBV-IRIS has passed in order to minimise the risk of hepatotoxicity. […] We report a high incidence of hepatotoxicity in people with advanced HIV taking IPT and ART, conclude the authors. Those with raised AST/ALT or with HBsAg seropositivity at baseline need closer monitoring for hepatotoxicity. There is need for further research on alternative TB preventative regimens that are less hepatotoxic in people with advanced HIV.

• #28 Patient education: Hepatitis B (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/hepatitis-b-beyond-the-basics/print

  Hepatitis B infection can be prevented by vaccination. Hepatitis B vaccines are safe and highly effective in preventing hepatitis B infection and are now given routinely to newborns and children in the United States and in many other countries. […] To help prevent transmission from mother to infant, all pregnant people should have a blood test for a marker of hepatitis B virus, called hepatitis B surface antigen (HBsAg). […] Immediate family, household members, and regular sexual partners should be tested for hepatitis B. Anyone who is at risk of hepatitis B infection should be vaccinated. […] If a pregnant person tests positive for hepatitis B surface antigen, certain steps can be taken to decrease the risk of transmitting the virus to their baby. These include: Antiviral medications may be recommended for the mother if the amount of virus in her blood (viral load) is high. […] Preventing HBV reactivation—If a person with chronic HBV infection needs to take medications that suppress their immune function, HBV can reactivate (multiply very quickly) and cause damage to the liver.

• #29 Toxic Hepatitis | UCSF Department of Surgery

  https://surgery.ucsf.edu/condition/toxic-hepatitis

  The first and most important step in treating toxic hepatitis is to identify and eliminate the substance that is causing the problem, such as medications, herbs or alcohol. […] Urgent liver transplantation should be considered for patients with life-threatening liver damage caused by a medication, herb or nutritional supplement.

• #30

  https://www.painscale.com/article/conventional-medical-treatments-for-toxic-hepatitis

  The first step in treating toxic hepatitis is identifying the cause and stopping exposure to the substance causing the condition. […] The liver is often able to heal itself, so early elimination of exposure to the substance that caused toxic hepatitis is usually enough to relieve symptoms and prevent further complications.

• #31 Hepatitis B or raised liver enzymes predict liver toxicity when TB prevention drug is combined with HIV treatment | aidsmap

  https://www.aidsmap.com/news/jun-2018/hepatitis-b-or-raised-liver-enzymes-predict-liver-toxicity-when-tb-prevention-drug

  The World Health Organization (WHO) recommends antiretroviral therapy (ART) and isoniazid preventive therapy (IPT) to prevent TB in people with HIV. These therapies are much more effective when used in conjunction rather than alone. However, ART and isoniazid have overlapping interactions and toxicities, and both can cause potentially serious liver toxicities. For these reasons, some physicians are reluctant to initiate concomitant ART and IPT. […] Isoniazid-related hepatotoxicity may be accompanied by symptoms such as fatigue, nausea, abdominal pain and loss of appetite. In more severe cases jaundice, itching and confusion indicate the onset of liver damage. WHO recommends that people taking IPT should be warned to contact their healthcare provider immediately if they experience any of these symptoms.

• #32 Toxic Hepatitis | Conditions | UCSF Health

  https://www.ucsfhealth.org/conditions/toxic-hepatitis

  The first and most important step in treating toxic hepatitis is to identify and eliminate the substance that is causing the problem, such as medications, herbs or alcohol. […] Urgent liver transplantation should be considered for patients with life-threatening liver damage caused by a medication, herb or nutritional supplement. […] Patients with end-stage cirrhosis from alcohol may be considered for transplantation. However, they are considered candidates for transplantation only if they have been completely abstinent from alcohol and in a treatment program for a minimum of six months.

• #33 Hepatitis treatment options | Liver Disease News

  https://liverdiseasenews.com/hepatitis-treatment-options/

  Toxic hepatitis occurs when chemicals or drugs damage the liver, leading to inflammation. Toxic hepatitis can be caused by alcohol and other recreational drugs, as well as certain industrial chemicals and herbal supplements. Some medications, including acetaminophen (sold as Tylenol, among others), also can cause toxic hepatitis especially at high doses. […] Treating toxic hepatitis generally involves identifying the substance that is causing liver damage, and then stopping exposure (e.g., abstaining from alcohol use). Usually, the liver is able to heal itself once the toxin is eliminated, but this recovery can take varying amounts of time depending on how much damage has accumulated. While the liver heals, supportive care such as hydration or pain relief may be given. […] In instances of toxic hepatitis due to acetaminophen (an analgesic and antipyretic agent, to reduce pain and fever), a medication called N-acetylcysteine (NAC) may be given to help remove the toxin from the body. NAC is almost 100% effective if it’s given within eight hours of taking a toxic dose of acetaminophen.

• #34 The course of toxic hepatitis at the stage of treatment consolidation acute leukemia in children | Hematology, Transfusion and Cell Therapy

  https://www.htct.com.br/en-the-course-toxic-hepatitis-at-articulo-S2531137920302583

  Objective: Toxic hepatitis occupies a special place among the complications of chemotherapy in the treatment of patients with acute leukemia. The research work we have presented is devoted to studying the frequency of toxic hepatitis and the choice of treatment tactics for children who are at the stage of consolidating acute leukemia. […] Conclusion: In the mild form of hepatitis from the intravenous use of Essentiale forte and Riboxin against the background of ongoing chemotherapy, a positive effect was obtained. With moderate severity, intravenous administration of Adeomethionine preparations (Heptral/Legend) in combination with Aevit per os turned out to be more effective. In 4 patients, upon transition to a severe form in the last course of consolidation, along with these drugs, ursodeoxycholic acid (Ursobil)+enhanced detoxification therapy was prescribed, which led to a complete recovery. After the treatment of toxic hepatitis, all patients with moderate and severe form, for the purpose of prevention, was prescribed combination therapy with Ursobil+Aevit+Lipoic acid, which gave a long-term positive effect.

• #35 Drugs and Chemicals That Cause Toxic Liver Disease

  https://www.webmd.com/fatty-liver-disease/toxic-liver-disease

  Prevention of hepatotoxicity is key. To protect your liver, be proactive by: […] Using medications responsibly. Take only the ones you need, and use them only as directed. […] Staying away from harmful substances. Steer clear of herbal supplements that could harm your liver. Talk to your doctor before you start any new medications or supplements. […] Follow safety guidelines. Read and follow all instructions and warnings for any chemicals you use, at home or on the job. Keep all chemicals and medications locked up in your home so that children or pets can’t eat them by mistake.

• #36 Toxic Hepatitis: Symptoms, Causes, Treatment | Qwark

  https://qwarkhealth.com/conditions/toxic-hepatitis

  Preventative measures for Toxic Hepatitis are numerous, and it is essential to take them seriously. First, individuals should always read and follow the label instructions before using chemicals or medications. […] Individuals can protect themselves from developing toxic hepatitis by being vigilant about the products they use and the environments in which they work. […] In addition to the preventative measures already mentioned, steps that can be taken to prevent the onset of toxic hepatitis include getting vaccinated for hepatitis A and B, avoiding drug and alcohol abuse, and maintaining a healthy lifestyle. […] Best practices for avoiding exposure to toxic substances that can cause hepatitis include reading and following label instructions, using appropriate protective equipment, storing chemicals and hazardous materials in appropriate locations, and working in well-ventilated areas. […] Businesses and organizations can ensure they are taking necessary precautions to prevent worker exposure to toxic substances by implementing workplace safety programs and providing regular training and education on handling hazardous materials.

• #37 Toxic Hepatitis | Health & Human Services

  https://hhs.iowa.gov/epi-manual-guide-surveillance-investigation-and-reporting/environmental-disease/toxic-hepatitis

  All cases diagnosed as chemical hepatitis or toxic hepatitis are required to be reported, including prolonged or possible overexposure to non-medicinal toxic agents other than ethyl alcohol, including, but not limited to, carbon tetrachloride, chloroform, tetrachloroethane, trichloroethylene, phosphorus, TNT, chloronapthalenes, methylenedianilines, ethylene dibromide, and organic solvents (this includes ICD-9 codes 572.2 and 573.3 or ICD-10 codes K71.0 to K71.9). Reporting is also required in cases in which there are any abnormal liver tissue biopsy findings that would be attributable to such exposure.

• #38 Hepatitis in dogs: Key steps to prevention and managing health | ManyPets

  https://manypets.com/uk/articles/hepatitis-in-dogs/

  You can’t realistically prevent every cause of hepatitis, but you can support a healthy liver in your dog. Here are a few ways to do that. […] With a blend of vaccinations, regular vet visits, a balanced diet, and a toxin-free environment, you can help build a robust shield against hepatitis for your dog. […] Identify and limit exposure to toxins. The liver is a detoxifying powerhouse, and exposure to toxins can overwhelm it, leading to inflammation and hepatitis. Be mindful of your dog’s environment, ensuring it’s free from harmful substances such as certain plants, foods, and chemicals. […] Consistent veterinary check-ups are crucial for tracking liver health and tweaking treatments as needed. […] Regular vet check-ups, a keen eye for symptoms, and a tailored diet can make a world of difference in the life of a hepatic dog.

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