Zapalenie mięśni
Objawy
Zapalenie mięśni (myositis) to grupa rzadkich chorób autoimmunologicznych charakteryzujących się przewlekłym zapaleniem mięśni, prowadzącym do symetrycznego osłabienia mięśni proksymalnych (np. szyi, barków, bioder, ud) oraz ich atrofii. Wyróżnia się podtypy takie jak zapalenie skórno-mięśniowe (dermatomyositis) z charakterystyczną wysypką, zapalenie wielomięśniowe (polymyositis) bez zmian skórnych, zapalenie mięśni z ciałkami wtrętowymi (IBM) o powolnym, asymetrycznym przebiegu oraz miositis nekrotyzującą, często o ostrym początku. Objawy obejmują osłabienie mięśni utrudniające codzienne czynności (wstawanie, chodzenie po schodach, unoszenie rąk), ból mięśni i stawów, dysfagię (w około 33% przypadków), duszność, a także powikłania ze strony układu oddechowego (śródmiąższowa choroba płuc u 30-40% pacjentów) i sercowego (zapalenie mięśnia sercowego, arytmie). Przebieg choroby jest przewlekły, z okresami zaostrzeń i remisji, a tempo progresji zależy od podtypu – np. IBM postępuje powoli, ale jest oporne na leczenie, podczas gdy polymyositis i dermatomyositis mogą reagować na terapię w ciągu 1-2 miesięcy.
- Co to jest zapalenie mięśni (myositis)?
- Główne objawy zapalenia mięśni
- Specyficzne objawy różnych typów zapalenia mięśni
- Zapalenie skórno-mięśniowe (Dermatomyositis)
- Zapalenie wielomięśniowe (Polymyositis)
- Zapalenie mięśni z ciałkami wtrętowymi (Inclusion Body Myositis)
- Miositis nekrotyzująca (Necrotizing Myopathy)
- Objawy systemowe i powikłania
- Czynniki wpływające na progresję choroby
- Remisje i zaostrzenia
- Długoterminowa prognoza
- Najważniejsze informacje o zapaleniu mięśni
Co to jest zapalenie mięśni (myositis)?
Zapalenie mięśni (myositis) to rzadka grupa chorób autoimmunologicznych charakteryzująca się przewlekłym stanem zapalnym mięśni, prowadzącym do ich osłabienia i uszkodzenia. W przebiegu tej choroby układ odpornościowy atakuje własne, zdrowe komórki mięśniowe, powodując przewlekły stan zapalny, który pojawia się i ustępuje przez dłuższy czas.12 Ostatecznie zapalenie to powoduje postępujące osłabienie mięśni, a czasem także ich ból. Myositis może dotknąć zarówno dzieci, jak i dorosłych, a objawy mogą rozwijać się stopniowo w ciągu tygodni, miesięcy, a nawet lat.34
Zapalenie mięśni nie ma znanego lekarstwa, jednak w większości przypadków odpowiednie leczenie może doprowadzić do remisji. Większość osób z zapaleniem mięśni zmaga się z chorobą przez całe życie.5 W niektórych przypadkach zapalenie mięśni może być śmiertelne – około 5% pacjentów z zapaleniem skórno-mięśniowym umiera w ciągu roku od diagnozy, co podkreśla znaczenie wczesnej diagnozy i leczenia.6
Główne objawy zapalenia mięśni
Podstawowym objawem zapalenia mięśni jest osłabienie mięśni, które może rozwijać się stopniowo i powodować trudności w wykonywaniu codziennych czynności.7 Osłabienie to jest zwykle symetryczne (dotyka obu stron ciała) i najczęściej dotyczy dużych grup mięśniowych blisko tułowia (mięśnie proksymalne), takich jak mięśnie szyi, barków, bioder i ud.8910
Do głównych objawów zapalenia mięśni należą:1112
- Osłabienie mięśni, które może utrudniać codzienne czynności
- Ból mięśni lub stawów
- Uczucie zmęczenia i wyczerpania
- Obrzęk mięśni
- Trudności z oddychaniem lub połykaniem
- Zaburzenia rytmu serca (jeśli zapalenie mięśni dotyka serca)
Podczas zaostrzenia objawów pacjenci mogą doświadczać trudności w poruszaniu się lub wykonywaniu czynności, które zazwyczaj wykonują bez problemu. Mogą szybciej się męczyć lub czuć, że nie mają kontroli nad swoimi kończynami.1516
Funkcje ruchowe i codzienne czynności
Zapalenie mięśni może znacząco wpływać na zdolność wykonywania podstawowych czynności. Pacjenci często zgłaszają następujące trudności:1718
- Problemy z wstawaniem z krzesła lub łóżka
- Trudności z wchodzeniem po schodach
- Problemy z podnoszeniem przedmiotów
- Trudności z unoszeniem rąk nad głowę (np. przy czesaniu, myciu włosów czy sięganiu po rzeczy na wyższych półkach)
- Częste potykanie się i upadki
- Niemożność podniesienia się z podłogi po upadku
W najcięższych przypadkach może dochodzić do osłabienia mięśni gardła lub przepony, co prowadzi do trudności w połykaniu (dysfagia) lub duszności.22 Około jednej trzeciej osób z zapaleniem mięśni doświadcza problemów z połykaniem.23
Progresja choroby
Progresja zapalenia mięśni jest zwykle powolna i stopniowa. Objawy mogą pojawiać się przez tygodnie, miesiące, a nawet lata, zanim zostaną zdiagnozowane.2425 Osłabienie mięśni zwykle nasila się z czasem, chociaż tempo progresji różni się w zależności od typu zapalenia mięśni i reakcji na leczenie.26
W przypadku zapalenia skórno-mięśniowego (dermatomyositis) i zapalenia wielomięśniowego (polymyositis), osłabienie mięśni zazwyczaj nasila się w ciągu tygodni lub miesięcy.27 Natomiast w przypadku zapalenia mięśni z ciałkami wtrętowymi (inclusion body myositis, IBM), osłabienie mięśni rozwija się wolniej i może postępować przez wiele lat.28
W miarę postępu choroby, u pacjentów może dojść do utraty masy mięśniowej (atrofia) i pogłębiania się niepełnosprawności. Większość pacjentów z IBM potrzebuje pomocy przy podstawowych czynnościach życia codziennego w ciągu 15 lat od diagnozy, a niektórzy będą potrzebować wózka inwalidzkiego.2930
Specyficzne objawy różnych typów zapalenia mięśni
Zapalenie mięśni obejmuje kilka różnych podtypów, z których każdy charakteryzuje się nieco odmiennymi objawami i przebiegiem.31
Zapalenie skórno-mięśniowe (Dermatomyositis)
Ten typ zapalenia mięśni charakteryzuje się zarówno osłabieniem mięśni, jak i charakterystycznymi zmianami skórnymi:3233
- Wyraźna, fioletowo-czerwona wysypka na twarzy (szczególnie wokół oczu), łokciach, kolanach, knykciach, klatce piersiowej lub plecach
- Wysypka może pojawić się przed, w trakcie lub po wystąpieniu objawów osłabienia mięśni
- Osłabienie mięśni zazwyczaj dotyka mięśni blisko tułowia (biodra, ramiona)
Zapalenie wielomięśniowe (Polymyositis)
Ten typ zapalenia mięśni charakteryzuje się przede wszystkim osłabieniem mięśni bez wysypki skórnej:36
- Stopniowe osłabienie mięśni, które zwykle zaczyna się od mięśni najbliższych tułowia (biodra, uda, ramiona, szyja)
- Osłabienie postępuje symetrycznie po obu stronach ciała
- Pacjenci mogą doświadczać trudności w chodzeniu, podnoszeniu przedmiotów i wstawaniu z pozycji siedzącej
- Niektórzy pacjenci mają również problemy z połykaniem, mówieniem lub oddychaniem
- Możliwa jest obecność bólu mięśni i stawów
Zapalenie mięśni z ciałkami wtrętowymi (Inclusion Body Myositis)
Jest to postępująca choroba zapalna i degeneracyjna mięśni, charakteryzująca się obecnością nieprawidłowych złogów białkowych (ciałek wtrętowych) w komórkach mięśniowych:4041
- Osłabienie mięśni rozwija się stopniowo, zazwyczaj po 50. roku życia
- Może początkowo dotykać mięśni nadgarstków, palców i ud
- Często atakuje jedną stronę ciała bardziej niż drugą (asymetrycznie)
- Częste upadki i potykanie się są często pierwszymi zauważalnymi objawami
- Do połowy pacjentów rozwija trudności w połykaniu
- Widoczny zanik mięśni (atrofia)
- Łagodny, częsty ból mięśni (mialgia)
Miositis nekrotyzująca (Necrotizing Myopathy)
Ten typ zapalenia mięśni charakteryzuje się obumartwicą komórek mięśniowych:45
- Objawy ekstremalne osłabienia mięśni i niemożność chodzenia mogą pojawić się nagle
- Osłabienie mięśni zazwyczaj dotyka mięśni blisko tułowia
- Mniejszy ból mięśni w porównaniu z innymi formami zapalenia mięśni
- Choroba może być wywołana przez długotrwałe przyjmowanie leków obniżających poziom cholesterolu (statyny)
Objawy systemowe i powikłania
Zapalenie mięśni to choroba, która może wpływać na wiele układów w organizmie, nie tylko na mięśnie szkieletowe.48 Pacjenci mogą doświadczać szeregu objawów ogólnoustrojowych i powikłań:
Układ oddechowy
Zapalenie mięśni może wpływać na mięśnie oddechowe, prowadząc do:4950
- Duszności i trudności w oddychaniu
- Przewlekłego, suchego kaszlu
- Śródmiąższowej choroby płuc – tkanka płucna pacjentów z zapaleniem mięśni może ulegać bliznowaceniu, co powoduje problemy z oddychaniem. Około 30-40% osób z zapaleniem mięśni ma jakąś formę choroby płuc
- Nadciśnienia płucnego
Układ pokarmowy
Zapalenie mięśni może wpływać na mięśnie przełyku i gardła, powodując:5455
- Dysfagię (trudności w połykaniu)
- Ryzyko aspiracji (wdychanie pokarmów i płynów do płuc), co może prowadzić do zapalenia płuc
- Zmianę głosu (chrypka lub głos nosowy)
- Refluks żołądkowo-przełykowy
- Osłabienie perystaltyki jelit prowadzące do zaparć
Układ sercowo-naczyniowy
W rzadkich przypadkach zapalenie mięśni może wpływać na mięsień sercowy, powodując:5960
- Zapalenie mięśnia sercowego (myocarditis)
- Zaburzenia rytmu serca (arytmie)
- Niewydolność serca
Inne objawy systemowe
Pacjenci z zapaleniem mięśni mogą również doświadczać:6364
- Ogólnego złego samopoczucia
- Utraty wagi
- Nocnych potów
- Podwyższonej temperatury
- Objawu Raynauda (zmiana koloru i drętwienie palców w niskich temperaturach)
- Bólu i obrzęku stawów
Czynniki wpływające na progresję choroby
Tempo i ciężkość progresji zapalenia mięśni są zróżnicowane i zależą od wielu czynników:6869
Typ zapalenia mięśni
Różne typy zapalenia mięśni mają różną dynamikę progresji:7071
- Zapalenie wielomięśniowe (Polymyositis) i zapalenie skórno-mięśniowe (Dermatomyositis) – zwykle reagują na leczenie i mogą osiągnąć remisję w ciągu 1-2 miesięcy
- Zapalenie mięśni z ciałkami wtrętowymi (IBM) – zazwyczaj postępuje powoli, ale jest oporne na leczenie
- Miositis nekrotyzująca – może mieć nagły początek i ciężki przebieg
Wiek i płeć
Wiek pojawienia się objawów może wpływać na przebieg choroby:7576
- Starszy wiek w momencie wystąpienia objawów jest często związany z szybszą progresją
- IBM występuje częściej u mężczyzn, szczególnie po 50. roku życia
- Zapalenie wielomięśniowe i skórno-mięśniowe występuje częściej u kobiet
Obecność przeciwciał
Obecność specyficznych przeciwciał może wpływać na przebieg choroby i ryzyko powikłań:8081
- Przeciwciała Jo-1 są związane ze zwiększonym ryzykiem rozwoju choroby śródmiąższowej płuc
- Przeciwciała SRP są związane z bardziej nagłym i ciężkim przebiegiem choroby
- Przeciwciała HMGCR mogą być związane z chorobą wywołaną przez statyny
Współistniejące choroby
Obecność dodatkowych chorób może wpływać na ciężkość przebiegu zapalenia mięśni:8485
- Choroba śródmiąższowa płuc
- Problemy z sercem
- Nowotwór związany z zapaleniem mięśni
- Inne choroby autoimmunologiczne (zespół nakładania)
Remisje i zaostrzenia
Zapalenie mięśni często przebiega z okresami remisji (ustąpienia objawów) i zaostrzeń (nasilenia objawów).8990 Pacjenci mogą doświadczać okresów, w których objawy są mniej lub bardziej nasilone, co jest charakterystyczną cechą tej przewlekłej choroby.
Charakterystyka zaostrzeń
Podczas zaostrzeń (rzutów) choroby, pacjenci mogą doświadczać:9192
- Nasilenia osłabienia mięśni
- Zwiększonego zmęczenia
- Nasilenia bólu mięśni i stawów
- Pogorszenia funkcji oddechowych i problemów z połykaniem
- Nasilenia wysypki (w przypadku zapalenia skórno-mięśniowego)
- Gorączki
- Utraty wagi
Czynniki wpływające na remisję
Osiągnięcie remisji zależy od kilku czynników:9596
- Wczesne rozpoczęcie leczenia
- Właściwe dostosowanie terapii
- Typ zapalenia mięśni (zapalenie wielomięśniowe i skórno-mięśniowe lepiej reagują na leczenie niż IBM)
- Brak lub minimalne uszkodzenie mięśni przed rozpoczęciem leczenia
- Współistniejące choroby
Długoterminowa prognoza
Długoterminowa prognoza dla pacjentów z zapaleniem mięśni zależy od typu choroby, czasu rozpoczęcia leczenia, odpowiedzi na leczenie i obecności powikłań.99100
Jakość życia i niepełnosprawność
Zapalenie mięśni może mieć znaczący wpływ na jakość życia i poziom niepełnosprawności:101102
- Niektórzy pacjenci mogą osiągnąć dobrą kontrolę objawów i zachować zdolność do wykonywania codziennych czynności
- Inni mogą doświadczać postępującej niepełnosprawności i wymagać pomocy w podstawowych czynnościach
- Część pacjentów może potrzebować korzystania z laski, chodzika lub wózka inwalidzkiego
Odzyskanie siły mięśniowej
Zdolność do odzyskania siły mięśniowej różni się w zależności od typu zapalenia mięśni:106107
- W przypadku zapalenia wielomięśniowego i skórno-mięśniowego, większość pacjentów odzyskuje przynajmniej część siły mięśniowej przy odpowiednim leczeniu
- Niektórzy pacjenci mogą osiągnąć całkowity powrót do normalnej siły mięśniowej
- Zapalenie mięśni z ciałkami wtrętowymi (IBM) zazwyczaj nie poprawia się znacząco pod wpływem leczenia
- Niektórzy pacjenci nigdy nie odzyskują pierwotnej siły i funkcji mięśni
Oczekiwana długość życia
Wpływ zapalenia mięśni na długość życia zależy od typu choroby i obecności powikłań:111112
- Zapalenie mięśni z ciałkami wtrętowymi (IBM) zazwyczaj nie wpływa na długość życia, chyba że wystąpią poważne powikłania
- W przypadku zapalenia wielomięśniowego i skórno-mięśniowego, ponad 95% pacjentów żyje dłużej niż 5 lat po diagnozie
- Głównymi przyczynami zgonów są infekcje (często z powodu obniżonej odporności w wyniku leczenia), nowotwory, choroby płuc i problemy z sercem
- Dysfagia (trudności z połykaniem) zwiększa ryzyko aspiracyjnego zapalenia płuc, które może prowadzić do śmierci
Najważniejsze informacje o zapaleniu mięśni
Zapalenie mięśni (myositis) jest rzadką chorobą autoimmunologiczną charakteryzującą się przewlekłym stanem zapalnym mięśni, prowadzącym do ich osłabienia i uszkodzenia.116 Objawy, które mogą pojawiać się stopniowo przez tygodnie, miesiące lub lata, obejmują przede wszystkim postępujące osłabienie mięśni, które utrudnia codzienne czynności takie jak wstawanie z krzesła, wchodzenie po schodach czy unoszenie rąk nad głowę.117118
Choroba może również wpływać na inne układy organizmu, powodując trudności w połykaniu, problemy z oddychaniem, zaburzenia rytmu serca oraz wysypkę skórną (w przypadku zapalenia skórno-mięśniowego).119120 Przebieg choroby charakteryzuje się okresami zaostrzeń i remisji, a długoterminowa prognoza zależy od typu zapalenia mięśni, czasu rozpoczęcia leczenia i odpowiedzi na terapię.121122
Choć zapalenie mięśni nie ma obecnie znanego lekarstwa, odpowiednie leczenie może prowadzić do kontroli objawów i poprawy jakości życia pacjentów.123124 Wczesna diagnoza i rozpoczęcie leczenia są kluczowe dla zapobiegania nieodwracalnemu uszkodzeniu mięśni i minimalizowania ryzyka poważnych powikłań.125126
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Materiały źródłowe
- #1 Myositis: Symptoms, Causes & Treatmenthttps://my.clevelandclinic.org/health/diseases/24170-myositis
Myositis makes your immune system attack your muscles. Depending on which type of myositis you have, youll have a hard time moving or using your affected muscles. Theres no cure for myositis, but in most cases, treatment can put it into remission. […] Myositis is a disease that makes your immune system attack your muscles. It causes chronic inflammation swelling that comes and goes over a long time. Eventually, this inflammation makes your muscles feel increasingly weak. It can also cause muscle pain. […] Myositis symptoms include: Muscle weakness. Joint or muscle pain. Fatigue. Swelling. Trouble breathing or swallowing. Arrhythmia (if the myositis affects your heart). […] During an episode of symptoms, you might have trouble moving or doing certain activities you usually can. You might get tired faster, or feel like you cant control your arms, hands or legs.
- #2 Myositis: Symptoms, Causes, Diagnosis and Treatmentshttps://www.webmd.com/a-to-z-guides/myositis-symptoms-treatments-prognosis
Myositis refers to a group of conditions that cause inflammation in muscles, but it can also refer to the muscle inflammation itself. This inflammation often leads to weakness, swelling, and pain over time, making it harder to do everyday activities, such as climbing stairs or reaching over your head. […] The main symptom of myositis is muscle weakness, which might be obvious or may only be found with testing. Muscle pain may or may not be present. […] In some types of myositis, such as dermatomyositis or polymyositis, muscle weakness typically worsens over weeks or months. It affects large muscle groups on both sides of the body, including the neck, shoulders, hips, and back. […] The weakness from myositis can make it harder to move around or stand up. Other symptoms that may be present include fatigue, difficulty swallowing, difficulty breathing, weight loss, and night sweats.
- #3 Myositis – OrthoInfo – AAOShttps://orthoinfo.aaos.org/en/diseases–conditions/myositis
Myositis is a rare disease in which the immune system chronically inflames (produces inflammation in) the body’s own healthy muscle tissue. Over time, this persistent inflammation weakens muscles, often resulting in muscle aches, pain, and fatigue. […] It usually develops slowly over time with symptoms that range in severity from mild to disabling. It can affect both children and adults. […] Symptoms of inclusion-body myositis typically begin after age 50 with very gradual weakening of muscles throughout the body. […] Although there is no cure for myositis, prompt and aggressive treatment to reduce inflammation of polymyositis and dermatomyositis can help prevent muscle weakness from progressing (getting worse over time) and might help restore some of your strength.
- #4https://www.singhealth.com.sg/patient-care/conditions-treatments/inflammatory-myositis
There are two main clusters of patients; children between the ages of 5 to 15 years and adults between the ages of 30 to 65 years. […] This condition causes the muscle to be weak and can also result in muscle ache and swelling. […] The major symptoms common to all forms of inflammatory myositis are muscle weakness and muscle pain. Other symptoms vary, depending on the specific cause of the disease. […] In dermatomyositis and polymyositis, weakness usually affects muscles near the centre of the body like the neck, shoulders and hips. […] General symptoms like lethargy, fatigue, weight loss and poor appetite are also very common. […] Most people with dermatomyositis and polymyositis eventually regain their strength with proper treatment. But there are risks of complications such as infections at the lungs arising from swallowing and breathing difficulties. […] Inclusion myositis usually progresses very slowly and does not affect a persons lifespan unless complications like infections set in. […] In most cases of drug-induced myositis, the symptoms subside when the offending drug is stopped.
- #5 Myositis: Symptoms, Causes & Treatmenthttps://my.clevelandclinic.org/health/diseases/24170-myositis
Theres no cure for myositis, but in most cases, treatment can put it into remission. Most people with myositis have it for the rest of their lives. […] Some cases of myositis can be fatal. Around 5% of people with dermatomyositis die within a year of their diagnosis. This is why its important to get your symptoms examined by a healthcare provider as soon as you notice them. […] Myositis is chronic muscle inflammation caused by your immune system attacking muscles throughout your body. Your symptoms will come and go in episodes, probably for the rest of your life. Even though theres no cure for myositis, your healthcare provider will help you find treatments and physical therapy exercises that will manage your symptoms.
- #6 Myositis: Symptoms, Causes & Treatmenthttps://my.clevelandclinic.org/health/diseases/24170-myositis
Theres no cure for myositis, but in most cases, treatment can put it into remission. Most people with myositis have it for the rest of their lives. […] Some cases of myositis can be fatal. Around 5% of people with dermatomyositis die within a year of their diagnosis. This is why its important to get your symptoms examined by a healthcare provider as soon as you notice them. […] Myositis is chronic muscle inflammation caused by your immune system attacking muscles throughout your body. Your symptoms will come and go in episodes, probably for the rest of your life. Even though theres no cure for myositis, your healthcare provider will help you find treatments and physical therapy exercises that will manage your symptoms.
- #7 Myositishttps://www.nhs.uk/conditions/myositis/
Myositis is the name for a group of rare conditions that cause weak muscles. It slowly gets worse over time, but treatment with medicines and exercise can help. […] The main symptom of myositis is muscle weakness, which can start very gradually and cause you to trip or fall over a lot. […] Depending on the type, other symptoms can include: painful or aching muscles, feeling very tired, weight loss, night sweats, a patchy, red rash, usually on the eyelids, face, neck and the backs of the hands this can look different on brown or black skin, problems with swallowing (dysphagia) or breathing. […] There may be times when your symptoms are better than at other times. […] It’s not possible to cure myositis, but treatment can help control the symptoms.
- #8 Myositis | Causes, symptoms, treatmenthttps://versusarthritis.org/about-arthritis/conditions/myositis/
Myositis is the name for a group of rare conditions that can cause muscles to become weak, tired and painful. […] The symptoms of myositis vary between different people. They can include: weak and tired muscles that can make everyday tasks such as climbing stairs, brushing hair, and getting in and out of cars difficult, pain in muscles, muscles feeling tender to touch, muscles can sometimes swell, generally feeling unwell, weight loss, night sweats. […] The weakening and tiredness in the muscles can make people with myositis more likely to fall over. […] In most cases the pain and feelings of being unwell are eased with drugs. Even in severe cases most people with myositis eventually respond to treatment. […] Muscle strength can take longer to get back to normal. Once myositis is controlled with treatment, exercises can also help to improve muscle strength.
- #9 Myositis: Symptoms, Causes, Diagnosis and Treatmentshttps://www.webmd.com/a-to-z-guides/myositis-symptoms-treatments-prognosis
Myositis refers to a group of conditions that cause inflammation in muscles, but it can also refer to the muscle inflammation itself. This inflammation often leads to weakness, swelling, and pain over time, making it harder to do everyday activities, such as climbing stairs or reaching over your head. […] The main symptom of myositis is muscle weakness, which might be obvious or may only be found with testing. Muscle pain may or may not be present. […] In some types of myositis, such as dermatomyositis or polymyositis, muscle weakness typically worsens over weeks or months. It affects large muscle groups on both sides of the body, including the neck, shoulders, hips, and back. […] The weakness from myositis can make it harder to move around or stand up. Other symptoms that may be present include fatigue, difficulty swallowing, difficulty breathing, weight loss, and night sweats.
- #10 Polymyositis – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/polymyositis/symptoms-causes/syc-20353208
Polymyositis (pol-e-my-o-SY-tis) is an uncommon inflammatory disease that causes muscle weakness affecting both sides of your body. Having this condition can make it difficult to climb stairs, rise from a seated position, lift objects or reach overhead. […] Signs and symptoms usually develop gradually, over weeks or months. […] The muscle weakness associated with polymyositis involves the muscles closest to the trunk, such as those in your hips, thighs, shoulders, upper arms and neck. The weakness affects both the left and right sides of your body, and tends to gradually worsen. […] Seek medical attention if you develop unexplained muscle weakness.
- #11 Myositis: Symptoms, Causes & Treatmenthttps://my.clevelandclinic.org/health/diseases/24170-myositis
Myositis makes your immune system attack your muscles. Depending on which type of myositis you have, youll have a hard time moving or using your affected muscles. Theres no cure for myositis, but in most cases, treatment can put it into remission. […] Myositis is a disease that makes your immune system attack your muscles. It causes chronic inflammation swelling that comes and goes over a long time. Eventually, this inflammation makes your muscles feel increasingly weak. It can also cause muscle pain. […] Myositis symptoms include: Muscle weakness. Joint or muscle pain. Fatigue. Swelling. Trouble breathing or swallowing. Arrhythmia (if the myositis affects your heart). […] During an episode of symptoms, you might have trouble moving or doing certain activities you usually can. You might get tired faster, or feel like you cant control your arms, hands or legs.
- #12 Myositis | Causes, symptoms, treatmenthttps://versusarthritis.org/about-arthritis/conditions/myositis/
Myositis is the name for a group of rare conditions that can cause muscles to become weak, tired and painful. […] The symptoms of myositis vary between different people. They can include: weak and tired muscles that can make everyday tasks such as climbing stairs, brushing hair, and getting in and out of cars difficult, pain in muscles, muscles feeling tender to touch, muscles can sometimes swell, generally feeling unwell, weight loss, night sweats. […] The weakening and tiredness in the muscles can make people with myositis more likely to fall over. […] In most cases the pain and feelings of being unwell are eased with drugs. Even in severe cases most people with myositis eventually respond to treatment. […] Muscle strength can take longer to get back to normal. Once myositis is controlled with treatment, exercises can also help to improve muscle strength.
- #13 Myositis: Symptoms, Causes & Treatmenthttps://my.clevelandclinic.org/health/diseases/24170-myositis
Myositis makes your immune system attack your muscles. Depending on which type of myositis you have, youll have a hard time moving or using your affected muscles. Theres no cure for myositis, but in most cases, treatment can put it into remission. […] Myositis is a disease that makes your immune system attack your muscles. It causes chronic inflammation swelling that comes and goes over a long time. Eventually, this inflammation makes your muscles feel increasingly weak. It can also cause muscle pain. […] Myositis symptoms include: Muscle weakness. Joint or muscle pain. Fatigue. Swelling. Trouble breathing or swallowing. Arrhythmia (if the myositis affects your heart). […] During an episode of symptoms, you might have trouble moving or doing certain activities you usually can. You might get tired faster, or feel like you cant control your arms, hands or legs.
- #14 Myositishttps://www.nhs.uk/conditions/myositis/
Myositis is the name for a group of rare conditions that cause weak muscles. It slowly gets worse over time, but treatment with medicines and exercise can help. […] The main symptom of myositis is muscle weakness, which can start very gradually and cause you to trip or fall over a lot. […] Depending on the type, other symptoms can include: painful or aching muscles, feeling very tired, weight loss, night sweats, a patchy, red rash, usually on the eyelids, face, neck and the backs of the hands this can look different on brown or black skin, problems with swallowing (dysphagia) or breathing. […] There may be times when your symptoms are better than at other times. […] It’s not possible to cure myositis, but treatment can help control the symptoms.
- #15 Myositis: Symptoms, Causes & Treatmenthttps://my.clevelandclinic.org/health/diseases/24170-myositis
Myositis makes your immune system attack your muscles. Depending on which type of myositis you have, youll have a hard time moving or using your affected muscles. Theres no cure for myositis, but in most cases, treatment can put it into remission. […] Myositis is a disease that makes your immune system attack your muscles. It causes chronic inflammation swelling that comes and goes over a long time. Eventually, this inflammation makes your muscles feel increasingly weak. It can also cause muscle pain. […] Myositis symptoms include: Muscle weakness. Joint or muscle pain. Fatigue. Swelling. Trouble breathing or swallowing. Arrhythmia (if the myositis affects your heart). […] During an episode of symptoms, you might have trouble moving or doing certain activities you usually can. You might get tired faster, or feel like you cant control your arms, hands or legs.
- #16 Myositis: Muscle Inflammation | Inflammatory Myopathy | HSShttps://www.hss.edu/condition-list_myositis.asp
Symptoms of myositis include muscle inflammation, weakness, fatigue and, in some people, muscle pain. But it can affect the whole body: Some patients can have other symptoms such as arthritis in the hands that resembles those in rheumatoid arthritis, lung inflammation that causes coughing or shortness of breath, and skin inflammation or rashes. Each patients disease experience and mix of symptoms is unique. Some cases are very mild, while others are severe. […] The most common symptom of myositis is muscle weakness. The weakness often develops slowly, and can be subtle at first, influencing patients ability to do certain activities. They can have trouble doing tasks that require having their arms held above their head things like washing, brushing, or blow drying their hair, reaching items on high shelves, or hanging up an overcoat can be hard. Additionally, they can have trouble getting up from low chairs, getting out of a car, or climbing steps. Patients can trip and be unable to catch themselves or be unable to get up from the floor after falling. Sometimes, in the most severe cases, the muscles of the throat or diaphragm can weaken, leading to trouble swallowing or shortness of breath.
- #17 Myositis: Muscle Inflammation | Inflammatory Myopathy | HSShttps://www.hss.edu/condition-list_myositis.asp
Symptoms of myositis include muscle inflammation, weakness, fatigue and, in some people, muscle pain. But it can affect the whole body: Some patients can have other symptoms such as arthritis in the hands that resembles those in rheumatoid arthritis, lung inflammation that causes coughing or shortness of breath, and skin inflammation or rashes. Each patients disease experience and mix of symptoms is unique. Some cases are very mild, while others are severe. […] The most common symptom of myositis is muscle weakness. The weakness often develops slowly, and can be subtle at first, influencing patients ability to do certain activities. They can have trouble doing tasks that require having their arms held above their head things like washing, brushing, or blow drying their hair, reaching items on high shelves, or hanging up an overcoat can be hard. Additionally, they can have trouble getting up from low chairs, getting out of a car, or climbing steps. Patients can trip and be unable to catch themselves or be unable to get up from the floor after falling. Sometimes, in the most severe cases, the muscles of the throat or diaphragm can weaken, leading to trouble swallowing or shortness of breath.
- #18 Myositis: Types, Symptoms, Causes, Diagnosis and Treatment Optionshttps://www.apollohospitals.com/diseases-and-conditions/myositis-types-symptoms-causes-diagnosis-and-treatment
Myositis symptoms include muscle pain, fatigue, soreness, trouble swallowing, and difficulty breathing. These symptoms may appear rapidly or gradually over time. […] Different types of myositis have their distinctive symptoms. However, the common symptoms are as follows: Weakness in the muscle, Pain in the muscle and joint, Tiredness, Inflammation, Breathing and swallowing difficulties, Arrhythmia. […] Patients with polymyositis may experience difficulty performing regular movements, such as standing up after sitting, climbing stairs, lifting, and reaching over the head. […] Other symptoms also include weakness and pain in the muscle, troubled swallowing and breathing, frequent falling, difficulty standing from a seated position, constant dry cough, fatigue, sudden onset of fever, and skin thickening on the hands.
- #19 Myositis: Muscle Inflammation | Inflammatory Myopathy | HSShttps://www.hss.edu/condition-list_myositis.asp
Symptoms of myositis include muscle inflammation, weakness, fatigue and, in some people, muscle pain. But it can affect the whole body: Some patients can have other symptoms such as arthritis in the hands that resembles those in rheumatoid arthritis, lung inflammation that causes coughing or shortness of breath, and skin inflammation or rashes. Each patients disease experience and mix of symptoms is unique. Some cases are very mild, while others are severe. […] The most common symptom of myositis is muscle weakness. The weakness often develops slowly, and can be subtle at first, influencing patients ability to do certain activities. They can have trouble doing tasks that require having their arms held above their head things like washing, brushing, or blow drying their hair, reaching items on high shelves, or hanging up an overcoat can be hard. Additionally, they can have trouble getting up from low chairs, getting out of a car, or climbing steps. Patients can trip and be unable to catch themselves or be unable to get up from the floor after falling. Sometimes, in the most severe cases, the muscles of the throat or diaphragm can weaken, leading to trouble swallowing or shortness of breath.
- #20 About Myositis – The Myositis Associationhttps://www.myositis.org/about-myositis/
Symptoms of weakness, swelling, and muscle damage often appear gradually. […] Long before patients are diagnosed, they may have trouble getting up from a chair, climbing stairs, or grasping objects with their hands. Patients may fall, find it difficult to reach their arms up, have difficulty swallowing, or other symptoms. […] Myositis is a serious illness that, in most cases, needs to be treated aggressively. With inadequate or no treatment, myositis can cause significant disability and even death.
- #21 RHEUM Symptoms-Myositis | Department of Medicinehttps://dom.pitt.edu/rheum/centers-institutes/myositiscenter/symptoms/
The hallmark feature of myositis is muscle weakness with an onset that is often insidious. Patients complain of proximal weakness with difficulty holding their arms above their head or getting up from a chair or walking up steps. […] Many other signs and symptoms occur such as fatigue, fever, Raynaud phenomenon, difficulty swallowing and joint pain, but pulmonary involvement is an important and serious feature commonly seen in patients with PM and DM. Such patients complain of dyspnea and may develop interstitial lung disease (ILD) alone or in combination with pulmonary hypertension.
- #22 Myositis: Muscle Inflammation | Inflammatory Myopathy | HSShttps://www.hss.edu/condition-list_myositis.asp
Symptoms of myositis include muscle inflammation, weakness, fatigue and, in some people, muscle pain. But it can affect the whole body: Some patients can have other symptoms such as arthritis in the hands that resembles those in rheumatoid arthritis, lung inflammation that causes coughing or shortness of breath, and skin inflammation or rashes. Each patients disease experience and mix of symptoms is unique. Some cases are very mild, while others are severe. […] The most common symptom of myositis is muscle weakness. The weakness often develops slowly, and can be subtle at first, influencing patients ability to do certain activities. They can have trouble doing tasks that require having their arms held above their head things like washing, brushing, or blow drying their hair, reaching items on high shelves, or hanging up an overcoat can be hard. Additionally, they can have trouble getting up from low chairs, getting out of a car, or climbing steps. Patients can trip and be unable to catch themselves or be unable to get up from the floor after falling. Sometimes, in the most severe cases, the muscles of the throat or diaphragm can weaken, leading to trouble swallowing or shortness of breath.
- #23 Myositis | Arthritis Foundationhttps://www.arthritis.org/diseases/myositis
Dermatomyositis causes patchy purple or red rashes on the face, eyelids, elbows, knees, toes, chest or back. These rashes can appear before, after or during symptoms of muscle weakness. […] Weakness of the throat muscles can cause trouble swallowing, called dysphagia. About one-third of people with myositis have trouble swallowing. […] Lung tissue in people with myositis can become scarred, which causes breathing problems. About 30 to 40 percent of people with myositis have some form of lung disease.
- #24 Myositis: Symptoms, Causes, Diagnosis and Treatmentshttps://www.webmd.com/a-to-z-guides/myositis-symptoms-treatments-prognosis
Myositis refers to a group of conditions that cause inflammation in muscles, but it can also refer to the muscle inflammation itself. This inflammation often leads to weakness, swelling, and pain over time, making it harder to do everyday activities, such as climbing stairs or reaching over your head. […] The main symptom of myositis is muscle weakness, which might be obvious or may only be found with testing. Muscle pain may or may not be present. […] In some types of myositis, such as dermatomyositis or polymyositis, muscle weakness typically worsens over weeks or months. It affects large muscle groups on both sides of the body, including the neck, shoulders, hips, and back. […] The weakness from myositis can make it harder to move around or stand up. Other symptoms that may be present include fatigue, difficulty swallowing, difficulty breathing, weight loss, and night sweats.
- #25 Polymyositis – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/polymyositis/symptoms-causes/syc-20353208
Polymyositis (pol-e-my-o-SY-tis) is an uncommon inflammatory disease that causes muscle weakness affecting both sides of your body. Having this condition can make it difficult to climb stairs, rise from a seated position, lift objects or reach overhead. […] Signs and symptoms usually develop gradually, over weeks or months. […] The muscle weakness associated with polymyositis involves the muscles closest to the trunk, such as those in your hips, thighs, shoulders, upper arms and neck. The weakness affects both the left and right sides of your body, and tends to gradually worsen. […] Seek medical attention if you develop unexplained muscle weakness.
- #26 Myositishttps://www.nhs.uk/conditions/myositis/
Myositis is the name for a group of rare conditions that cause weak muscles. It slowly gets worse over time, but treatment with medicines and exercise can help. […] The main symptom of myositis is muscle weakness, which can start very gradually and cause you to trip or fall over a lot. […] Depending on the type, other symptoms can include: painful or aching muscles, feeling very tired, weight loss, night sweats, a patchy, red rash, usually on the eyelids, face, neck and the backs of the hands this can look different on brown or black skin, problems with swallowing (dysphagia) or breathing. […] There may be times when your symptoms are better than at other times. […] It’s not possible to cure myositis, but treatment can help control the symptoms.
- #27 Myositis: Symptoms, Causes, Diagnosis and Treatmentshttps://www.webmd.com/a-to-z-guides/myositis-symptoms-treatments-prognosis
Myositis refers to a group of conditions that cause inflammation in muscles, but it can also refer to the muscle inflammation itself. This inflammation often leads to weakness, swelling, and pain over time, making it harder to do everyday activities, such as climbing stairs or reaching over your head. […] The main symptom of myositis is muscle weakness, which might be obvious or may only be found with testing. Muscle pain may or may not be present. […] In some types of myositis, such as dermatomyositis or polymyositis, muscle weakness typically worsens over weeks or months. It affects large muscle groups on both sides of the body, including the neck, shoulders, hips, and back. […] The weakness from myositis can make it harder to move around or stand up. Other symptoms that may be present include fatigue, difficulty swallowing, difficulty breathing, weight loss, and night sweats.
- #28 Inclusion body myositis (IBM) – Autoimmune Associationhttps://autoimmune.org/disease-information/inclusion-body-myositis-ibm/
Inclusion body myositis (IBM) is one of a group of autoimmune related muscle diseases known as the inflammatory myopathies, which are characterized by chronic, progressive muscle inflammation accompanied by muscle weakness. The onset of muscle weakness in IBM is generally gradual (over months or years) and affects both proximal (close to the trunk of the body) and distal (further away from the trunk) muscles. […] Muscle weakness may affect only one side of the body. Falling and tripping are usually the first noticeable symptoms of IBM. […] Inclusion body myositis (IBM) is a progressive muscle disorder characterized by muscle inflammation, weakness, and atrophy (wasting). It is a type of inflammatory myopathy. IBM develops in adulthood, usually after age 50. The symptoms and rate of progression vary from person to person.
- #29 Inclusion body myositis (IBM) – Autoimmune Associationhttps://autoimmune.org/disease-information/inclusion-body-myositis-ibm/
Most people with IBM progress to disability over a period of years. In general, the older a person is when IBM begins, the more rapid the progression of the condition. Most people need assistance with basic daily activities within 15 years, and some people will need to use a wheelchair. […] Lifespan is thought to be normal, but severe complications (e.g. aspiration pneumonia) can lead to loss of life.
- #30 Inclusion Body Myositis (IBM): Symptoms & Treatmenthttps://my.clevelandclinic.org/health/diseases/15700-inclusion-body-myositis
If you have IBM, itll continue to slowly progress. It wont affect your life expectancy, but itll affect your quality of life. You may need to learn to rely on others more or learn new ways of doing things. Most people dont lose the ability to walk, but some may need a wheelchair after 10 to 15 years. […] Youll likely be living a long time with inclusion body myositis, and itll gradually become more challenging. The best way forward is to adopt a long-term plan to take care of your physical and mental health.
- #31 Myositis: All You Need to Knowhttps://www.healthline.com/health/myositis
Myositis is a progressive inflammation of the muscles that may also manifest with a skin rash. […] Symptoms of myositis may appear rapidly or gradually over time and often include muscle pain and soreness, fatigue, trouble swallowing, and difficulty breathing. […] Muscle weakness usually follows the development of the heliotrope rash. […] IBM begins with muscle weakness in the wrists, fingers, and thigh muscles. […] Like other forms of myositis, muscle weakness and a skin rash are hallmark features of JM. […] Polymyositis (PM) begins with muscle weakness in the muscles closest to the trunk and then expands to the limbs. […] Symptoms of toxic myositis are similar to those of other types of myositis. […] No cure has been found yet for myositis. Some people with severe cases of myositis may require the use of a cane, walker, or wheelchair to move independently. […] Treatment is effective for managing symptoms and preventing complications, and some people may experience partial or complete remission (symptom relief). […] Myositis is a rare autoimmune condition that often manifests with symptoms like persistent fatigue, muscle weakness, and a skin rash.
- #32 Myositis | Arthritis Foundationhttps://www.arthritis.org/diseases/myositis
Myositis causes muscle swelling and damage. […] Myositis refers to any condition that causes muscle inflammation. Polymyositis and dermatomyositis are the two of the most common types. Polymyositis causes muscle weakness in both sides of the body, usually in the hips, thighs, shoulders, upper arms and neck. Dermatomyositis causes muscle weakness as well as a skin rash. […] Symptoms of myositis usually develop gradually and include muscle weakness, muscle swelling, muscle pain or soreness, fatigue, difficulty moving limbs or lifting arms, and falls. […] Polymyositis and dermatomyositis often come with periods of worsening symptoms (flares). In addition to the ones listed above, symptoms may include joint pain, shortness of breath, trouble swallowing, fever, weight loss, and Raynaud’s phenomenon.
- #33 Myositis | Arthritis Foundationhttps://www.arthritis.org/diseases/myositis
Dermatomyositis causes patchy purple or red rashes on the face, eyelids, elbows, knees, toes, chest or back. These rashes can appear before, after or during symptoms of muscle weakness. […] Weakness of the throat muscles can cause trouble swallowing, called dysphagia. About one-third of people with myositis have trouble swallowing. […] Lung tissue in people with myositis can become scarred, which causes breathing problems. About 30 to 40 percent of people with myositis have some form of lung disease.
- #34 Myositis: Types, Symptoms, Causes, Diagnosis and Treatment Optionshttps://www.apollohospitals.com/diseases-and-conditions/myositis-types-symptoms-causes-diagnosis-and-treatment
The symptoms of inclusion body myositis are as follows: Difficulty using hands and fingers to perform precise and mundane tasks, such as buttoning a shirt or tying a shoelace, Gripping small objects, Troubled walking or standing, Swallowing, Frequently tripping, falling, and loss of balance, Difficulty in getting up from a seated position, Weakness in the muscle, Pain in the muscle and swallowing issues, Decreased deep tendon reflexes. […] The following are the symptoms of dermatomyositis: Dry, scaly, or rough skin with rashes, Presence of lumps over the knuckles, elbows, and knees that are often raised and scaly and easily break out, Difficult getting up from a seated position, Fatigue, Weakness in the muscle present in the neck, hip, back, and shoulders, Troubled swallowing, Hoarse voice, Pain in the muscle and inflammation of the joint, Solidified lumps of calcium under the skin, Abnormalities in the nail bed, Weight loss, Arrhythmia, Gastrointestinal ulcers.
- #35 Myositis: Causes, Symptoms, and Classification — ALKIVIA Studyhttps://www.alkiviamyositis.com/myositis-causes-symptoms-and-classification
Myositis is known as inflammatory myopathies; however, people may confuse it with other diseases like arthritis, which has inflammation as a symptom. These rare conditions are caused by the immune system mistakenly attacking the bodys own cells, as it would attack a virus, with antibodies. This action triggers an internal inflammatory process that can destroy healthy, normal cells, and cause muscle weakness. As a result, you may have heard your doctor refer to your condition as autoimmune myositis. […] SYMPTOMS VARY FOR THE DIFFERENT TYPES OF MYOSITIS […] Dermatomyositis the most common and distinct symptom is a skin rash or redness, which commonly appears around the eyes. Muscle weakness usually affects the muscles close to the trunk of the body like hips and shoulders instead of arms and legs. Both the skin rash and muscle weakness can develop slowly, over a number of weeks or months. Some people may not have any muscle weakness, just the rash. This type of myositis is diagnosed after testing positive for the dermatomyositis-specific antibody.
- #36 Polymyositis – What is it? How is it treated? – Myositis UKhttps://www.myositis.org.uk/myositis-info/conditions/polymyositis/
Polymyositis (PM) is a form of myositis a rare disease that causes muscle weakness and inflammation in adults. […] The main symptoms are weakness and inflammation of the muscles (poly means many, myo means muscle, and itis means inflammation). The muscular weakness may be progressive and can be severely disabling. […] The main symptoms of polymyositis are weak and painful muscles, tiredness and feelings of depression. Some people may also have joint pains. […] Some may have the disease for months or even years before it is realised, but most notice within weeks if they have developed muscular weakness. […] The weakness results in difficulty in walking, lifting arms and getting up from the sitting and lying down positions. There may even be some trouble in swallowing and the voice may become nasal or deeper in quality.
- #37 Polymyositis – What is it? How is it treated? – Myositis UKhttps://www.myositis.org.uk/myositis-info/conditions/polymyositis/
Polymyositis (PM) is a form of myositis a rare disease that causes muscle weakness and inflammation in adults. […] The main symptoms are weakness and inflammation of the muscles (poly means many, myo means muscle, and itis means inflammation). The muscular weakness may be progressive and can be severely disabling. […] The main symptoms of polymyositis are weak and painful muscles, tiredness and feelings of depression. Some people may also have joint pains. […] Some may have the disease for months or even years before it is realised, but most notice within weeks if they have developed muscular weakness. […] The weakness results in difficulty in walking, lifting arms and getting up from the sitting and lying down positions. There may even be some trouble in swallowing and the voice may become nasal or deeper in quality.
- #38 Polymyositis – What is it? How is it treated? – Myositis UKhttps://www.myositis.org.uk/myositis-info/conditions/polymyositis/
Depression and a general feeling of unhappiness is very noticeable and can be an indication of the disease before any sign of muscle weakness. […] Other possible symptoms of the illnesses include fever and weight loss. […] There is no cure for polymyositis yet, but there are treatment options to help manage the symptoms. […] Once the disease has been diagnosed, most patients respond well to steroids. […] A second line of treatment is immunosuppressive medication. […] If the patient does not respond to these treatments then intermittent (pulsed) treatment can be given intravenously or plasma exchanges would be considered. […] In addition to medication, exercise and physiotherapy can help ease the symptoms of polyyositis. […] Exercise is encouraged even in early phases of the condition, guided by your doctor and physiotherapist.
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- #40 Inclusion Body Myositis (IBM): Symptoms & Treatmenthttps://my.clevelandclinic.org/health/diseases/15700-inclusion-body-myositis
Inclusion body myositis is an inflammatory and degenerative muscle disease. It features abnormal protein deposits called inclusion bodies that cluster inside your muscle cells and contribute to weakening them. Over time, youll notice your limbs growing increasingly weaker, and you may develop difficulties with ordinary tasks. […] Inclusion body myositis (IBM) is a degenerative muscle disease that causes gradual and painless weakening of your muscles. Symptoms usually appear after the age of 50. You might notice that you start to have trouble pinching and grasping objects, or that youve started tripping and falling a lot. […] IBM progresses over several years. It isnt life-threatening, but it can become disabling over time. It may affect one side of your body more than the other. Up to half of people develop swallowing difficulties. Theres no cure, but physical therapy can help you preserve as much of your mobility as possible.
- #41 Inclusion Body Myositis | National Institute of Neurological Disorders and Strokehttps://www.ninds.nih.gov/health-information/disorders/inclusion-body-myositis
Inclusion body myositis (IBM) is one of a group of muscle diseases known as the inflammatory myopathies, which are characterized by chronic, progressive muscle inflammation accompanied by muscle weakness. […] The onset of muscle weakness in IBM is generally gradual (over months or years) and affects both proximal (close to the chest) and distal (further away from the chest) muscles. Muscle weakness may affect only one side of the body. Falling and tripping are usually the first noticeable symptoms. […] There may be weakness of the wrist and finger muscles and atrophy (thinning or loss of muscle bulk) of the forearm muscles and quadricep muscles in the legs. Difficulty swallowing occurs in approximately half of IBM cases. […] Symptoms of the disease usually begin after the age of 50, although the disease can occur earlier. IBM occurs more frequently in men than in women. […] However, IBM is generally resistant to all therapies and its rate of progression appears to be unaffected by currently available treatments.
- #42 Inclusion Body Myositis (IBM): Symptoms & Treatmenthttps://my.clevelandclinic.org/health/diseases/15700-inclusion-body-myositis
Muscle weakness from IBM occurs gradually and usually begins in your limbs. You might notice it in your lower body (legs and feet) or upper body (arms, wrists and fingers) first. Some people notice a lack of dexterity when they try to button their shirts or write with pens. Others might start tripping and falling. […] As symptoms progress, you might notice: Increasing muscle weakness in your arms, legs, shoulders, hips, hands and feet. Muscle weakness in your neck or esophagus, causing difficulties lifting your head or swallowing. Visible muscle atrophy (thinning and wasting of your muscles). Mild, frequent muscle pain (myalgia). […] Theres no effective course of treatment for inclusion body myositis. Unlike other inflammatory and autoimmune conditions, it doesnt respond to corticosteroids or immunosuppressant drugs. But physical therapy and regular exercise are crucial to preserving your muscle strength as much as possible.
- #43 Inclusion Body Myositis – Symptoms | Cure IBMhttps://cureibm.org/diagnosis/symptoms/
Inclusion body myositis symptoms are due to muscle weakness, usually beginning in middle-age or later, and worsen gradually over several years. […] General symptoms of IBM include fatigue and overall loss of strength. […] Physicians should consider IBM whenever an adult patient, especially one over age 40, presents with unexplained frequent falls, trouble standing from a low chair, weak grip, or trouble swallowing. […] Trouble standing up from a low chair or toilet is a typical inclusion body myositis symptom. […] Many patients gradually progress from a cane, to a walker, to a wheelchair. […] Weak grip is another early inclusion body myositis symptom. […] Swallowing difficulty, known as dysphagia, eventually affects many patients, but is an uncommon early symptom of inclusion body myositis.
- #44 Inclusion Body Myositis (IBM) | Johns Hopkins Myositis Centerhttps://www.hopkinsmyositis.org/myositis/inclusion-body-myositis/
Inclusion body myositis (IBM) is an inflammatory muscle disease characterized by progressive muscle weakness and wasting. Patients suffering from IBM usually develop symptoms of IBM after age 50; however, some patients may present with symptoms as early as their 30s. Patients typically develop difficulty in swallowing (dysphagia), weak wrists or fingers and atrophy of the forearms and/or thigh muscles. […] muscle weakness often progresses slowly over months or years […] weakness in the thighs, wrists and fingers […] difficulty is swallowing (dysphagia) […] patients may have a history of frequent falls.
- #45 Myositis: Causes, Symptoms, and Classification — ALKIVIA Studyhttps://www.alkiviamyositis.com/myositis-causes-symptoms-and-classification
Immune-mediated necrotizing myopathy (IMNM) – symptoms of extreme muscle weakness and inability to walk can come on suddenly, especially with people who have the SRP antibody. For those who have the HMGCR antibody, the symptoms can be more gradual and not as severe, and may be triggered by long-term cholesterol-lowering medications, known as statins. […] Sporadic Inclusion Body Myositis (sIBM) – the most common type of myositis in the elderly, mostly in men. Symptoms of muscle weakness come on gradually as muscles deteriorate, and, commonly, when weakness in the knees causes a fall. A muscle biopsy can reveal the extent of the muscle damage. This type of condition is often misdiagnosed as polymyositis. […] Polymyositis – usually found more frequently in women and people over the age of 20. It affects many different muscles, but in particular shoulders, hips, and thighs. It is associated with the use of certain medications, like statins (a common cholesterol medication). It can also be present along with other autoimmune diseases, such as Sjgren’s syndrome or celiac disease, often known as Overlap Syndromes.
- #46 Myositis: Causes, Symptoms, and Classification — ALKIVIA Studyhttps://www.alkiviamyositis.com/myositis-causes-symptoms-and-classification
Immune-mediated necrotizing myopathy (IMNM) – symptoms of extreme muscle weakness and inability to walk can come on suddenly, especially with people who have the SRP antibody. For those who have the HMGCR antibody, the symptoms can be more gradual and not as severe, and may be triggered by long-term cholesterol-lowering medications, known as statins. […] Sporadic Inclusion Body Myositis (sIBM) – the most common type of myositis in the elderly, mostly in men. Symptoms of muscle weakness come on gradually as muscles deteriorate, and, commonly, when weakness in the knees causes a fall. A muscle biopsy can reveal the extent of the muscle damage. This type of condition is often misdiagnosed as polymyositis. […] Polymyositis – usually found more frequently in women and people over the age of 20. It affects many different muscles, but in particular shoulders, hips, and thighs. It is associated with the use of certain medications, like statins (a common cholesterol medication). It can also be present along with other autoimmune diseases, such as Sjgren’s syndrome or celiac disease, often known as Overlap Syndromes.
- #47 Myositis | University of Michigan Healthhttps://www.uofmhealth.org/conditions-treatments/rheumatology/myositis
It is marked by muscle cell death (necrosis). This manifests in muscle weakness but patients also complain of fatigue and overall general tiredness. […] Some additional symptoms include trouble lifting the head, a hoarse voice, stomach aches, hardened lumps under the skin and irritability. […] Currently, there are no FDA-approved therapies for any form of myositis. […] Moving the muscles reduces inflammation and fatigue while increasing stamina and muscle mass. […] Eating foods on an anti-inflammatory plan, sometimes called the Mediterranean diet, may minimize flare-ups.
- #48 Myositis: Muscle Inflammation | Inflammatory Myopathy | HSShttps://www.hss.edu/condition-list_myositis.asp
Symptoms of myositis include muscle inflammation, weakness, fatigue and, in some people, muscle pain. But it can affect the whole body: Some patients can have other symptoms such as arthritis in the hands that resembles those in rheumatoid arthritis, lung inflammation that causes coughing or shortness of breath, and skin inflammation or rashes. Each patients disease experience and mix of symptoms is unique. Some cases are very mild, while others are severe. […] The most common symptom of myositis is muscle weakness. The weakness often develops slowly, and can be subtle at first, influencing patients ability to do certain activities. They can have trouble doing tasks that require having their arms held above their head things like washing, brushing, or blow drying their hair, reaching items on high shelves, or hanging up an overcoat can be hard. Additionally, they can have trouble getting up from low chairs, getting out of a car, or climbing steps. Patients can trip and be unable to catch themselves or be unable to get up from the floor after falling. Sometimes, in the most severe cases, the muscles of the throat or diaphragm can weaken, leading to trouble swallowing or shortness of breath.
- #49 Myositis | Arthritis Foundationhttps://www.arthritis.org/diseases/myositis
Dermatomyositis causes patchy purple or red rashes on the face, eyelids, elbows, knees, toes, chest or back. These rashes can appear before, after or during symptoms of muscle weakness. […] Weakness of the throat muscles can cause trouble swallowing, called dysphagia. About one-third of people with myositis have trouble swallowing. […] Lung tissue in people with myositis can become scarred, which causes breathing problems. About 30 to 40 percent of people with myositis have some form of lung disease.
- #50 Idiopathic Inflammatory Myopathies – Musculoskeletal and Connective Tissue Disorders – Merck Manual Professional Editionhttps://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/systemic-rheumatic-diseases/idiopathic-inflammatory-myopathies
Onset of an inflammatory myopathy may be acute (particularly in children) or insidious (particularly in adults). […] Muscle weakness may progress over weeks to months. Patients may have difficulty raising their arms above their shoulders (eg, to brush their hair), climbing steps, or rising from a sitting position. Sometimes muscle tenderness and atrophy are present in addition to weakness. Patients may require the use of a wheelchair or become bedridden because of weakness of pelvic and shoulder girdle muscles. The flexors of the neck may be severely affected, causing an inability to raise the head from the pillow. Involvement of pharyngeal and upper esophageal muscles may impair swallowing and predispose to aspiration. […] Severe disease is characterized by dysphagia, dysphonia, and/or diaphragmatic weakness.
- #51 Idiopathic Inflammatory Myopathies – Musculoskeletal and Connective Tissue Disorders – Merck Manual Professional Editionhttps://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/systemic-rheumatic-diseases/idiopathic-inflammatory-myopathies
Joint manifestations include polyarthralgia or polyarthritis with swelling and other characteristics of nondeforming arthritis. […] Occasionally, and especially in patients with antisynthetase antibodies, interstitial lung disease and associated pulmonary hypertension (manifested by dyspnea and cough) are the most prominent manifestations. […] Characteristic skin changes can occur in the absence of muscle disease (amyopathic dermatomyositis).
- #52 Myositis Causes, Symptoms, and Treatments | UPMChttps://www.upmc.com/services/rheumatology/conditions/myositis
Myositis can affect how you walk, move your arms and hands, swallow, and breathe. […] Myositis can cause problems in muscle groups and other symptoms throughout the body. This includes muscles in the arms and legs as well as the muscles that help you swallow. Myositis can also attack the heart and lungs, causing shortness of breath. […] Myositis symptoms and complications vary by type and severity. They may come on all of a sudden or slowly get worse over time. […] Myositis symptoms and complications include: A rash on your face, knuckles, or elsewhere on the body. […] Breathing problems (if it’s attacking the lung tissue). […] Weakness that makes it hard to lift your arms. […] No, there’s no cure for myositis, but early treatment can prevent further muscle weakness.
- #53 Myositis | University of Michigan Healthhttps://www.uofmhealth.org/conditions-treatments/rheumatology/myositis
Myositis is an autoimmune muscle disease, where the immune system attacks its own tissue, causing inflammation in the muscles. This weakens the muscles over time and can cause pain. This chronic condition typically impacts the neck, shoulders, hips and back. […] Patients often first notice the weakening by tripping or falling. Others experience trouble climbing stairs, getting up from a seat or reaching for objects overhead. Some also have unusual rashes, breathing problems or difficulty swallowing (dysaphgia). […] It progresses more slowly than other forms and manifests in the smaller muscles of the hands and forearms, impacting a persons grip and fine motor skills. Larger muscles decline as well. […] Not only does it hamper a patients ability to walk, run, or get up after a fall, but it often causes a chronic dry cough or difficulty swallowing (dysaphgia).
- #54 Myositis: Muscle Inflammation | Inflammatory Myopathy | HSShttps://www.hss.edu/condition-list_myositis.asp
Symptoms of myositis include muscle inflammation, weakness, fatigue and, in some people, muscle pain. But it can affect the whole body: Some patients can have other symptoms such as arthritis in the hands that resembles those in rheumatoid arthritis, lung inflammation that causes coughing or shortness of breath, and skin inflammation or rashes. Each patients disease experience and mix of symptoms is unique. Some cases are very mild, while others are severe. […] The most common symptom of myositis is muscle weakness. The weakness often develops slowly, and can be subtle at first, influencing patients ability to do certain activities. They can have trouble doing tasks that require having their arms held above their head things like washing, brushing, or blow drying their hair, reaching items on high shelves, or hanging up an overcoat can be hard. Additionally, they can have trouble getting up from low chairs, getting out of a car, or climbing steps. Patients can trip and be unable to catch themselves or be unable to get up from the floor after falling. Sometimes, in the most severe cases, the muscles of the throat or diaphragm can weaken, leading to trouble swallowing or shortness of breath.
- #55 Myositis Causes, Symptoms, and Treatments | UPMChttps://www.upmc.com/services/rheumatology/conditions/myositis
Myositis can affect how you walk, move your arms and hands, swallow, and breathe. […] Myositis can cause problems in muscle groups and other symptoms throughout the body. This includes muscles in the arms and legs as well as the muscles that help you swallow. Myositis can also attack the heart and lungs, causing shortness of breath. […] Myositis symptoms and complications vary by type and severity. They may come on all of a sudden or slowly get worse over time. […] Myositis symptoms and complications include: A rash on your face, knuckles, or elsewhere on the body. […] Breathing problems (if it’s attacking the lung tissue). […] Weakness that makes it hard to lift your arms. […] No, there’s no cure for myositis, but early treatment can prevent further muscle weakness.
- #56 Polymyositis | Better Health Channelhttps://www.betterhealth.vic.gov.au/health/conditionsandtreatments/polymyositis
Polymyositis is a connective tissue disease that triggers inflammation and muscular weakness. […] The symptoms include: The shoulders and hips usually affected first, Muscular weakness, Muscle wastage, Muscle pain, Fatigue, Breathlessness, Swallowing difficulties, Tremors, particularly of the hands, Wide-footed stance and walking style, Clumsiness, Tendency to fall over. […] Polymyositis develops gradually over weeks or months. By the time the person experiences symptoms, they have already lost around half of their muscle fibres to the disease. […] Difficulties may include: Profound muscular weakness in affected body parts, such as being unable to lift the arms above shoulder height or lift the head off a pillow, Voice changes, if the muscles of the larynx are affected, Problems with swallowing if the oesophagus is affected, with a tendency to regurgitate food, Peristalsis (the muscular contractions of the bowel) may falter, leading to constipation, In its later stages, abnormal shortening of muscles (contracture).
- #57 Prognosis – The Myositis Associationhttps://www.myositis.org/about-myositis/treatment-disease-management/prognosis/
Prognosis for the different forms of myositis vary greatly and often depend on the presence of other conditions, such as interstitial lung disease or certain autoantibodies. […] While inclusion body myositis is a progressive disease, life expectancy for those with IBM is usually the same as for those without the disease. In fact, IBM patients usually dont die from the disease, but from complications (often preventable) that are associated with it. Patients who develop impaired swallowing, for example, are at greater risk for aspiration (inhaling food and fluids into the lungs), which causes pneumonia and may lead to death. Similarly, injuries that occur as a result of falling, such as hip fractures and head injuries, also increase the likelihood of dying. […] For dermatomyositis, polymyositis, and necrotizing myopathy, the progression of the disease is more complicated and harder to predict. More than 95 percent of those with DM, PM, and NM are still alive more than five years after diagnosis. Many experience only one period of acute illness in their lifetime; others struggle with symptoms for years.
- #58 LIVING WITH MYOSITIS: HOW TO COPE WITH MUSCLE INFLAMMATION | Mya Carehttps://myacare.com/blog/living-with-myositis-how-to-cope-with-muscle-inflammation
Myositis is a general term that means inflammation of the muscles. It refers to several autoimmune muscle diseases that can cause muscle weakness, pain, and sometimes skin rashes. […] The main symptom of myositis is muscle weakness and fatigue in the muscles near the torso, such as the upper arms and thighs. It is challenging to carry out regular tasks, including walking, climbing stairs, lifting goods, or reaching aloft, due to the weakness of these muscles. It may be gradual or sudden and may affect one or more parts of the body. […] Other symptoms of myositis may include muscle pain and tenderness, fatigue, and trouble swallowing or breathing. During a flare up, symptoms of weakness and fatigue can intensify and be accompanied by weight loss, joint inflammation, and fever. […] Myositis can also affect other organs, such as the lungs, heart, and digestive system. This can lead to respiratory, cardiac, and digestive symptoms, including chest pain, bloating, indigestion, and constipation.
- #59https://arthritis.ca/about-arthritis/arthritis-types-(a-z)/types/myositis-(dermatomyositis,-polymyositis)
In inclusion-body myositis, the muscle weakness usually affects one side of the body (asymmetrical), and involves muscles on the back of the arm and hand that extend the fingers. […] Skin Rash: Dermatomyositis is a myositis associated with the presence of a specific skin rash. This skin rash may precede, accompany or follow muscle weakness. […] Joint Pain: Inflammatory joint pain and/or swelling may precede or accompany muscle weakness. […] Lung Involvement: Myositis can cause weakness of the muscles required for breathing, resulting in coughing and shortness of breath. […] Heart Involvement: In rare cases myositis can cause inflammation of the heart muscle (myocarditis), resulting in poor heart function (called congestive heart failure). […] Calcium Deposits: The skin and muscles can become hardened due to an accumulation of calcium salt deposits. This process, called calcification, doesn’t often occur in adults with the disease, but children with dermatomyositis may develop calcium deposits years after the disease starts.
- #60 Myositis | ColumbiaDoctorshttps://www.columbiadoctors.org/treatments-conditions/myositis
Myositis frequently occurs with other conditions, which share similar symptoms or affected organs. […] Depending on how long the myositis symptoms have occurred and which muscles are affected, heart muscle or lung tissue can also become inflamed, leading to poor health consequences like heart arrhythmias and interstitial lung disease. […] Specific symptoms include: Gradual, worsening weakness that develops over a period of weeks or months, Difficulty rising from a seated position or reaching above your head, Difficulty swallowing, Joint pain, General, unexplained fatigue.
- #61 Myositis: Symptoms, Causes, Diagnosis, and Treatmenthttps://www.verywellhealth.com/myositis-overview-4778444
Myositis literally means muscle inflammation. The term myositis also describes the group of conditions called inflammatory myopathies that cause chronic muscle inflammation, damage, weakness, and (sometimes) pain. […] Chronic (ongoing) inflammation, over time, destroys muscle fibers, causing muscle function loss, immobility, and fatigue. […] Symptoms of polymyositis develop gradually over weeks or months, and may include: Inflammation and weakness in the muscles responsible for movement, Weakness in the proximal musclesâthose closest to the chest and abdomen, although the distal muscles (lower arms, hands, lower legs, feet, etc.) may be affected as the disease progresses, Arthritis, including mild joint or muscle tenderness, Shortness of breath, Problems with swallowing and speaking, Fatigue, Heart arrhythmiasâimproper heart rhythm, whether irregular, too fast, or too slow.
- #62 Myositis: Symptoms, Causes & Treatmenthttps://my.clevelandclinic.org/health/diseases/24170-myositis
Myositis makes your immune system attack your muscles. Depending on which type of myositis you have, youll have a hard time moving or using your affected muscles. Theres no cure for myositis, but in most cases, treatment can put it into remission. […] Myositis is a disease that makes your immune system attack your muscles. It causes chronic inflammation swelling that comes and goes over a long time. Eventually, this inflammation makes your muscles feel increasingly weak. It can also cause muscle pain. […] Myositis symptoms include: Muscle weakness. Joint or muscle pain. Fatigue. Swelling. Trouble breathing or swallowing. Arrhythmia (if the myositis affects your heart). […] During an episode of symptoms, you might have trouble moving or doing certain activities you usually can. You might get tired faster, or feel like you cant control your arms, hands or legs.
- #63 Myositis | Causes, symptoms, treatmenthttps://versusarthritis.org/about-arthritis/conditions/myositis/
Myositis is the name for a group of rare conditions that can cause muscles to become weak, tired and painful. […] The symptoms of myositis vary between different people. They can include: weak and tired muscles that can make everyday tasks such as climbing stairs, brushing hair, and getting in and out of cars difficult, pain in muscles, muscles feeling tender to touch, muscles can sometimes swell, generally feeling unwell, weight loss, night sweats. […] The weakening and tiredness in the muscles can make people with myositis more likely to fall over. […] In most cases the pain and feelings of being unwell are eased with drugs. Even in severe cases most people with myositis eventually respond to treatment. […] Muscle strength can take longer to get back to normal. Once myositis is controlled with treatment, exercises can also help to improve muscle strength.
- #64 Myositis | Arthritis Foundationhttps://www.arthritis.org/diseases/myositis
Myositis causes muscle swelling and damage. […] Myositis refers to any condition that causes muscle inflammation. Polymyositis and dermatomyositis are the two of the most common types. Polymyositis causes muscle weakness in both sides of the body, usually in the hips, thighs, shoulders, upper arms and neck. Dermatomyositis causes muscle weakness as well as a skin rash. […] Symptoms of myositis usually develop gradually and include muscle weakness, muscle swelling, muscle pain or soreness, fatigue, difficulty moving limbs or lifting arms, and falls. […] Polymyositis and dermatomyositis often come with periods of worsening symptoms (flares). In addition to the ones listed above, symptoms may include joint pain, shortness of breath, trouble swallowing, fever, weight loss, and Raynaud’s phenomenon.
- #65 Inflammatory Myositis, Autoimmune Disease | Symptoms & Treatment | ARAPChttps://arapc.com/inflammatory-myositis/
Myositis is characterized by the onset over several weeks of weakness in muscles close to the trunk â the upper arms/shoulders, thighs and sometimes the neck. Weakness is due to muscle inflammation and subsequent muscle damage. While weakness is the most prominent symptom, muscle soreness can also occur. Patients may notice difficulty getting out of a chair, putting things away in overhead cabinets, or trouble climbing stairs due to weakness rather than pain. Other symptoms can include shortness of breath from lung inflammation, joint pain, Raynaudâs syndrome (finger color changes and numbness in cold weather), and trouble swallowing. Patients with dermatomyositis often develop several different kinds of rashes including one on the hands (Gottronâs papules), a violet discoloration or swelling around the eyes (heliotrope), and/or across the back and chest (shawl rash; see images below).
- #66 Myositis Symptoms | National Jewish Healthhttps://www.nationaljewish.org/conditions/myositis/symptoms
As an autoimmune disease that mostly targets muscles, myositis most obvious symptoms manifest themselves in muscle fatigue and pain. The disease may have many other symptoms. Common symptoms of myositis include: […] Muscle weakness […] Muscle pains […] Rashes […] Fatigue […] Weight loss […] Low-grade fevers […] Arthritis […] Color changes of hands and feet with cold exposure (known as Raynauds) […] Difficulty swallowing […] Heartburn […] Cough […] Shortness of breath. Studies have shown that people with myositis have a higher risk of developing different types of cancer. The vast majority of people with myositis do not develop cancer. It is important to be aware of this association and perform age-appropriate cancer screening.
- #67 Polymyositis – What is it? How is it treated? – Myositis UKhttps://www.myositis.org.uk/myositis-info/conditions/polymyositis/
Depression and a general feeling of unhappiness is very noticeable and can be an indication of the disease before any sign of muscle weakness. […] Other possible symptoms of the illnesses include fever and weight loss. […] There is no cure for polymyositis yet, but there are treatment options to help manage the symptoms. […] Once the disease has been diagnosed, most patients respond well to steroids. […] A second line of treatment is immunosuppressive medication. […] If the patient does not respond to these treatments then intermittent (pulsed) treatment can be given intravenously or plasma exchanges would be considered. […] In addition to medication, exercise and physiotherapy can help ease the symptoms of polyyositis. […] Exercise is encouraged even in early phases of the condition, guided by your doctor and physiotherapist.
- #68 Inclusion body myositis (IBM) – Autoimmune Associationhttps://autoimmune.org/disease-information/inclusion-body-myositis-ibm/
Most people with IBM progress to disability over a period of years. In general, the older a person is when IBM begins, the more rapid the progression of the condition. Most people need assistance with basic daily activities within 15 years, and some people will need to use a wheelchair. […] Lifespan is thought to be normal, but severe complications (e.g. aspiration pneumonia) can lead to loss of life.
- #69 Prognosis – The Myositis Associationhttps://www.myositis.org/about-myositis/treatment-disease-management/prognosis/
Prognosis for the different forms of myositis vary greatly and often depend on the presence of other conditions, such as interstitial lung disease or certain autoantibodies. […] While inclusion body myositis is a progressive disease, life expectancy for those with IBM is usually the same as for those without the disease. In fact, IBM patients usually dont die from the disease, but from complications (often preventable) that are associated with it. Patients who develop impaired swallowing, for example, are at greater risk for aspiration (inhaling food and fluids into the lungs), which causes pneumonia and may lead to death. Similarly, injuries that occur as a result of falling, such as hip fractures and head injuries, also increase the likelihood of dying. […] For dermatomyositis, polymyositis, and necrotizing myopathy, the progression of the disease is more complicated and harder to predict. More than 95 percent of those with DM, PM, and NM are still alive more than five years after diagnosis. Many experience only one period of acute illness in their lifetime; others struggle with symptoms for years.
- #70 Prognosis – The Myositis Associationhttps://www.myositis.org/about-myositis/treatment-disease-management/prognosis/
Prognosis for the different forms of myositis vary greatly and often depend on the presence of other conditions, such as interstitial lung disease or certain autoantibodies. […] While inclusion body myositis is a progressive disease, life expectancy for those with IBM is usually the same as for those without the disease. In fact, IBM patients usually dont die from the disease, but from complications (often preventable) that are associated with it. Patients who develop impaired swallowing, for example, are at greater risk for aspiration (inhaling food and fluids into the lungs), which causes pneumonia and may lead to death. Similarly, injuries that occur as a result of falling, such as hip fractures and head injuries, also increase the likelihood of dying. […] For dermatomyositis, polymyositis, and necrotizing myopathy, the progression of the disease is more complicated and harder to predict. More than 95 percent of those with DM, PM, and NM are still alive more than five years after diagnosis. Many experience only one period of acute illness in their lifetime; others struggle with symptoms for years.
- #71 Myositis – Harvard Healthhttps://www.health.harvard.edu/diseases-and-conditions/myositis-a-to-z
In polymyositis and dermatomyositis, weakness usually affects the muscles near the center of the body (called proximal muscles), including the muscles of the neck, shoulders, and hips, causing difficulty with lifting, reaching over the head, or rising from a chair. […] In inclusion body myositis, weakness typically starts in the upper legs and later affects the upper arms and muscles farther away from the center of the body (called distal muscles), including muscles of the hand and wrist and lower legs. Muscle wasting (atrophy) is often prominent. Up to half of these patients have trouble swallowing. […] Polymyositis and dermatomyositis are usually chronic (long-lasting), but typically improve after one to two months of treatment. Inclusion body myositis is also chronic. Since there is no reliably effective treatment for inclusion body myositis, symptoms usually worsen gradually over a period of years.
- #72 Myositis – Harvard Healthhttps://www.health.harvard.edu/diseases-and-conditions/myositis-a-to-z
In polymyositis and dermatomyositis, weakness usually affects the muscles near the center of the body (called proximal muscles), including the muscles of the neck, shoulders, and hips, causing difficulty with lifting, reaching over the head, or rising from a chair. […] In inclusion body myositis, weakness typically starts in the upper legs and later affects the upper arms and muscles farther away from the center of the body (called distal muscles), including muscles of the hand and wrist and lower legs. Muscle wasting (atrophy) is often prominent. Up to half of these patients have trouble swallowing. […] Polymyositis and dermatomyositis are usually chronic (long-lasting), but typically improve after one to two months of treatment. Inclusion body myositis is also chronic. Since there is no reliably effective treatment for inclusion body myositis, symptoms usually worsen gradually over a period of years.
- #73
- #74 Myositis: Symptoms, Causes, Diagnosis and Treatmentshttps://www.webmd.com/a-to-z-guides/myositis-symptoms-treatments-prognosis
Most muscle pain is caused by strain injuries or ordinary illnesses, such as colds and flu, not myositis. […] If you have any symptoms of myositis, make sure you talk to your doctor. […] Because many conditions can cause muscle weakness and pain, and testing for myositis isn’t always a straightforward process, getting a proper diagnosis can take some time. […] While there’s no cure for myositis, there are ways to manage your symptoms. […] With the right treatment, myositis may go into remission, meaning your symptoms could go away entirely. […] Living with myositis can be challenging, and setbacks can happen even when you follow your doctors recommendations. […] Myositis affects muscles in different ways, and its severity can vary from person to person. While there’s no cure, you can manage symptoms such as weakness, pain, and fatigue through medication, physical therapy, and lifestyle changes.
- #75 Inclusion body myositis (IBM) – Autoimmune Associationhttps://autoimmune.org/disease-information/inclusion-body-myositis-ibm/
Most people with IBM progress to disability over a period of years. In general, the older a person is when IBM begins, the more rapid the progression of the condition. Most people need assistance with basic daily activities within 15 years, and some people will need to use a wheelchair. […] Lifespan is thought to be normal, but severe complications (e.g. aspiration pneumonia) can lead to loss of life.
- #76 Polymyositis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK563129/
Polymyositis, being a chronic disease, is associated with a grave prognosis in the long run. […] The majority of patients usually respond to steroid therapy. This disease has the worst prognosis in patients having refractory disease, older females, Blacks, and patients having systematic involvement. […] Although polymyositis is a rare disease, it has been found to be associated with increased morbidity and mortality due to its associated comorbid conditions, eg, the involvement of major vessels or the gastrointestinal tract. […] Polymyositis affects the distal musculature of the esophagus in the late stage of the disease in up to 70% of the patients, leading to the inability to swallow, as well as regurgitation problems that can cause aspiration pneumonia.
- #77 Inclusion Body Myositis | National Institute of Neurological Disorders and Strokehttps://www.ninds.nih.gov/health-information/disorders/inclusion-body-myositis
Inclusion body myositis (IBM) is one of a group of muscle diseases known as the inflammatory myopathies, which are characterized by chronic, progressive muscle inflammation accompanied by muscle weakness. […] The onset of muscle weakness in IBM is generally gradual (over months or years) and affects both proximal (close to the chest) and distal (further away from the chest) muscles. Muscle weakness may affect only one side of the body. Falling and tripping are usually the first noticeable symptoms. […] There may be weakness of the wrist and finger muscles and atrophy (thinning or loss of muscle bulk) of the forearm muscles and quadricep muscles in the legs. Difficulty swallowing occurs in approximately half of IBM cases. […] Symptoms of the disease usually begin after the age of 50, although the disease can occur earlier. IBM occurs more frequently in men than in women. […] However, IBM is generally resistant to all therapies and its rate of progression appears to be unaffected by currently available treatments.
- #78 Myositis: Causes, Symptoms, and Classification — ALKIVIA Studyhttps://www.alkiviamyositis.com/myositis-causes-symptoms-and-classification
Immune-mediated necrotizing myopathy (IMNM) – symptoms of extreme muscle weakness and inability to walk can come on suddenly, especially with people who have the SRP antibody. For those who have the HMGCR antibody, the symptoms can be more gradual and not as severe, and may be triggered by long-term cholesterol-lowering medications, known as statins. […] Sporadic Inclusion Body Myositis (sIBM) – the most common type of myositis in the elderly, mostly in men. Symptoms of muscle weakness come on gradually as muscles deteriorate, and, commonly, when weakness in the knees causes a fall. A muscle biopsy can reveal the extent of the muscle damage. This type of condition is often misdiagnosed as polymyositis. […] Polymyositis – usually found more frequently in women and people over the age of 20. It affects many different muscles, but in particular shoulders, hips, and thighs. It is associated with the use of certain medications, like statins (a common cholesterol medication). It can also be present along with other autoimmune diseases, such as Sjgren’s syndrome or celiac disease, often known as Overlap Syndromes.
- #79 Polymyositis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK563129/
Polymyositis, being a chronic disease, is associated with a grave prognosis in the long run. […] The majority of patients usually respond to steroid therapy. This disease has the worst prognosis in patients having refractory disease, older females, Blacks, and patients having systematic involvement. […] Although polymyositis is a rare disease, it has been found to be associated with increased morbidity and mortality due to its associated comorbid conditions, eg, the involvement of major vessels or the gastrointestinal tract. […] Polymyositis affects the distal musculature of the esophagus in the late stage of the disease in up to 70% of the patients, leading to the inability to swallow, as well as regurgitation problems that can cause aspiration pneumonia.
- #80 Prognosis – The Myositis Associationhttps://www.myositis.org/about-myositis/treatment-disease-management/prognosis/
Prognosis for the different forms of myositis vary greatly and often depend on the presence of other conditions, such as interstitial lung disease or certain autoantibodies. […] While inclusion body myositis is a progressive disease, life expectancy for those with IBM is usually the same as for those without the disease. In fact, IBM patients usually dont die from the disease, but from complications (often preventable) that are associated with it. Patients who develop impaired swallowing, for example, are at greater risk for aspiration (inhaling food and fluids into the lungs), which causes pneumonia and may lead to death. Similarly, injuries that occur as a result of falling, such as hip fractures and head injuries, also increase the likelihood of dying. […] For dermatomyositis, polymyositis, and necrotizing myopathy, the progression of the disease is more complicated and harder to predict. More than 95 percent of those with DM, PM, and NM are still alive more than five years after diagnosis. Many experience only one period of acute illness in their lifetime; others struggle with symptoms for years.
- #81 Polymyositis – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/polymyositis/diagnosis-treatment/drc-20353212
If your doctor suspects you have polymyositis, he or she might suggest some of the following tests: […] A blood test will let your doctor know if you have elevated levels of muscle enzymes, which can indicate muscle damage. A blood test can also detect specific autoantibodies associated with different symptoms of polymyositis, which can help in determining the best medication and treatment. […] Although there’s no cure for polymyositis, treatment can improve your muscle strength and function. The earlier treatment is started in the course of polymyositis, the more effective it is leading to fewer complications. […] The most commonly used medications to treat polymyositis include: […] Drugs such as prednisone can be very effective in controlling polymyositis symptoms. […] Depending on the severity of your symptoms, your doctor might suggest:
- #82 Myositis: Causes, Symptoms, and Classification — ALKIVIA Studyhttps://www.alkiviamyositis.com/myositis-causes-symptoms-and-classification
Immune-mediated necrotizing myopathy (IMNM) – symptoms of extreme muscle weakness and inability to walk can come on suddenly, especially with people who have the SRP antibody. For those who have the HMGCR antibody, the symptoms can be more gradual and not as severe, and may be triggered by long-term cholesterol-lowering medications, known as statins. […] Sporadic Inclusion Body Myositis (sIBM) – the most common type of myositis in the elderly, mostly in men. Symptoms of muscle weakness come on gradually as muscles deteriorate, and, commonly, when weakness in the knees causes a fall. A muscle biopsy can reveal the extent of the muscle damage. This type of condition is often misdiagnosed as polymyositis. […] Polymyositis – usually found more frequently in women and people over the age of 20. It affects many different muscles, but in particular shoulders, hips, and thighs. It is associated with the use of certain medications, like statins (a common cholesterol medication). It can also be present along with other autoimmune diseases, such as Sjgren’s syndrome or celiac disease, often known as Overlap Syndromes.
- #83 Polymyositis and Dermatomyositis Causes, Symptoms, Treatment, Preventionhttps://www.medicinenet.com/polymyositis/article.htm
Muscle Pain Polymyositis is a disease of muscle featuring inflammation of the muscle fibers. Polymyositis is a chronic illness featuring progressive muscle weakness with periods of increased symptoms, called flares or relapses, and minimal or no symptoms, known as remissions. […] The weakness of muscles is the most common symptom of polymyositis. The onset can be gradual or rapid. This results in varying degrees of loss of muscle power and atrophy. The loss of strength can be noticed as difficulty getting up from chairs, walking, climbing stairs, or lifting above the shoulders. […] Patients can ultimately do well, especially with early medical treatment of disease and disease flares. The disease frequently becomes inactive, and rehabilitation of atrophied muscle becomes a long-term project. The presence of Jo-1 antibody, a myositis antibody, is predictive of an increased risk for the development of inflammation of the tissues of the lungs (interstitial lung disease). This can lead to permanent suboptimal lung function. […] The outcome for patients with polymyositis varies. While some have a relatively brief illness followed by remission not requiring subsequent treatment, others develop episodes of remissions and exacerbations requiring more or less treatment.
- #84 Prognosis – The Myositis Associationhttps://www.myositis.org/about-myositis/treatment-disease-management/prognosis/
Of those who die early in the disease course, the most frequent cause is not the myositis itself, but infection due to suppressed immunity as a result of treatment. […] Complications contributing to mortality include myositis-associated cancer, dysphagia (trouble swallowing), interstitial lung disease, and heart problems.
- #85 Myositis | ColumbiaDoctorshttps://www.columbiadoctors.org/treatments-conditions/myositis
Myositis frequently occurs with other conditions, which share similar symptoms or affected organs. […] Depending on how long the myositis symptoms have occurred and which muscles are affected, heart muscle or lung tissue can also become inflamed, leading to poor health consequences like heart arrhythmias and interstitial lung disease. […] Specific symptoms include: Gradual, worsening weakness that develops over a period of weeks or months, Difficulty rising from a seated position or reaching above your head, Difficulty swallowing, Joint pain, General, unexplained fatigue.
- #86 Prognosis – The Myositis Associationhttps://www.myositis.org/about-myositis/treatment-disease-management/prognosis/
Of those who die early in the disease course, the most frequent cause is not the myositis itself, but infection due to suppressed immunity as a result of treatment. […] Complications contributing to mortality include myositis-associated cancer, dysphagia (trouble swallowing), interstitial lung disease, and heart problems.
- #87 Myositis: Causes, Symptoms, and Classification — ALKIVIA Studyhttps://www.alkiviamyositis.com/myositis-causes-symptoms-and-classification
Immune-mediated necrotizing myopathy (IMNM) – symptoms of extreme muscle weakness and inability to walk can come on suddenly, especially with people who have the SRP antibody. For those who have the HMGCR antibody, the symptoms can be more gradual and not as severe, and may be triggered by long-term cholesterol-lowering medications, known as statins. […] Sporadic Inclusion Body Myositis (sIBM) – the most common type of myositis in the elderly, mostly in men. Symptoms of muscle weakness come on gradually as muscles deteriorate, and, commonly, when weakness in the knees causes a fall. A muscle biopsy can reveal the extent of the muscle damage. This type of condition is often misdiagnosed as polymyositis. […] Polymyositis – usually found more frequently in women and people over the age of 20. It affects many different muscles, but in particular shoulders, hips, and thighs. It is associated with the use of certain medications, like statins (a common cholesterol medication). It can also be present along with other autoimmune diseases, such as Sjgren’s syndrome or celiac disease, often known as Overlap Syndromes.
- #88 Lupus and myositis: Symptoms and how to copehttps://www.medicalnewstoday.com/articles/lupus-myositis
Myositis, or idiopathic inflammatory myopathy, is a neuromuscular autoimmune disease that causes inflammation and weakness of the muscles. Myositis affects the muscles, respiratory system, and heart. It can also cause digestive problems. […] The goal of myositis treatment is to reduce pain, increase muscle strength, and improve organ function. […] The outlook for people with myositis varies greatly. Although treatment can reduce symptoms, many people with myositis develop permanent muscle weakness and skin problems. […] Risk factors for a less favorable outlook in myositis include lung disease, swallowing difficulties, and speech problems. Myositis is also a risk factor for cancer.
- #89https://arthritis.ca/about-arthritis/arthritis-types-(a-z)/types/myositis-(dermatomyositis,-polymyositis)
Myositis typically affects the large muscles of the arms and legs on both sides of the body, but can also affect muscles associated with swallowing or breathing, and in rare cases can affect the heart as well. […] With treatment, patients can achieve periods of no active symptoms (remission), but the disease tends to recur with periods of active symptoms (flare). […] Muscle Weakness: Usually, the main symptom of myositis is muscle weakness. At the onset of the disease it generally affects the thighs and hips. If you have myositis, you may have difficulty climbing stairs or rising from low surfaces. The distance you are able to walk may eventually be limited because your muscles get too tired. […] If myositis affects your neck, chest and abdomen muscles it may be hard to lift your head from a pillow or get out of bed. Polymyositis can also cause you to have trouble swallowing or talking, though these are less common results of the disease.
- #90 Myositishttps://www.nhs.uk/conditions/myositis/
Myositis is the name for a group of rare conditions that cause weak muscles. It slowly gets worse over time, but treatment with medicines and exercise can help. […] The main symptom of myositis is muscle weakness, which can start very gradually and cause you to trip or fall over a lot. […] Depending on the type, other symptoms can include: painful or aching muscles, feeling very tired, weight loss, night sweats, a patchy, red rash, usually on the eyelids, face, neck and the backs of the hands this can look different on brown or black skin, problems with swallowing (dysphagia) or breathing. […] There may be times when your symptoms are better than at other times. […] It’s not possible to cure myositis, but treatment can help control the symptoms.
- #91 Myositis | Arthritis Foundationhttps://www.arthritis.org/diseases/myositis
Myositis causes muscle swelling and damage. […] Myositis refers to any condition that causes muscle inflammation. Polymyositis and dermatomyositis are the two of the most common types. Polymyositis causes muscle weakness in both sides of the body, usually in the hips, thighs, shoulders, upper arms and neck. Dermatomyositis causes muscle weakness as well as a skin rash. […] Symptoms of myositis usually develop gradually and include muscle weakness, muscle swelling, muscle pain or soreness, fatigue, difficulty moving limbs or lifting arms, and falls. […] Polymyositis and dermatomyositis often come with periods of worsening symptoms (flares). In addition to the ones listed above, symptoms may include joint pain, shortness of breath, trouble swallowing, fever, weight loss, and Raynaud’s phenomenon.
- #92 Polymyositis and Dermatomyositis Causes, Symptoms, Treatment, Preventionhttps://www.medicinenet.com/polymyositis/article.htm
Muscle Pain Polymyositis is a disease of muscle featuring inflammation of the muscle fibers. Polymyositis is a chronic illness featuring progressive muscle weakness with periods of increased symptoms, called flares or relapses, and minimal or no symptoms, known as remissions. […] The weakness of muscles is the most common symptom of polymyositis. The onset can be gradual or rapid. This results in varying degrees of loss of muscle power and atrophy. The loss of strength can be noticed as difficulty getting up from chairs, walking, climbing stairs, or lifting above the shoulders. […] Patients can ultimately do well, especially with early medical treatment of disease and disease flares. The disease frequently becomes inactive, and rehabilitation of atrophied muscle becomes a long-term project. The presence of Jo-1 antibody, a myositis antibody, is predictive of an increased risk for the development of inflammation of the tissues of the lungs (interstitial lung disease). This can lead to permanent suboptimal lung function. […] The outcome for patients with polymyositis varies. While some have a relatively brief illness followed by remission not requiring subsequent treatment, others develop episodes of remissions and exacerbations requiring more or less treatment.
- #93 LIVING WITH MYOSITIS: HOW TO COPE WITH MUSCLE INFLAMMATION | Mya Carehttps://myacare.com/blog/living-with-myositis-how-to-cope-with-muscle-inflammation
Myositis is a general term that means inflammation of the muscles. It refers to several autoimmune muscle diseases that can cause muscle weakness, pain, and sometimes skin rashes. […] The main symptom of myositis is muscle weakness and fatigue in the muscles near the torso, such as the upper arms and thighs. It is challenging to carry out regular tasks, including walking, climbing stairs, lifting goods, or reaching aloft, due to the weakness of these muscles. It may be gradual or sudden and may affect one or more parts of the body. […] Other symptoms of myositis may include muscle pain and tenderness, fatigue, and trouble swallowing or breathing. During a flare up, symptoms of weakness and fatigue can intensify and be accompanied by weight loss, joint inflammation, and fever. […] Myositis can also affect other organs, such as the lungs, heart, and digestive system. This can lead to respiratory, cardiac, and digestive symptoms, including chest pain, bloating, indigestion, and constipation.
- #94 How Do I Explain Myositis? – Myositis Support and Understandinghttps://understandingmyositis.org/explaining-myositis/
Myositis affects each person differently including changing symptoms, abilities, therapies and side effects. […] Myositis is a chronic disease and you will have Myositis for the rest of your life, although some do achieve remission, or as we like to call it disease stability. […] Myositis causes a variety of symptoms and affects each person differently. Muscle weakness, muscle pain, uncomfortable-itchy-painful skin rashes, debilitating fatigue, trouble breathing, achy joints, heart arrhythmias, and many other symptoms makes Myositis a very complex disease. […] Myositis is unpredictable. Some may reach remission (symptoms stabilize or improve) and some may battle ongoing disease and/or periods of flares (symptoms worsen). The unpredictability can be frustrating for us as patients and for family members and friends. […] Grieving the loss of our normal lives is a normal process that can take time. When you add disease progression, you may find you are going through the process of grieving many times during your life such as when you lose another ability. Take the time to grieve.
- #95 Myositis: Symptoms, Causes, Diagnosis and Treatmentshttps://www.webmd.com/a-to-z-guides/myositis-symptoms-treatments-prognosis
Most muscle pain is caused by strain injuries or ordinary illnesses, such as colds and flu, not myositis. […] If you have any symptoms of myositis, make sure you talk to your doctor. […] Because many conditions can cause muscle weakness and pain, and testing for myositis isn’t always a straightforward process, getting a proper diagnosis can take some time. […] While there’s no cure for myositis, there are ways to manage your symptoms. […] With the right treatment, myositis may go into remission, meaning your symptoms could go away entirely. […] Living with myositis can be challenging, and setbacks can happen even when you follow your doctors recommendations. […] Myositis affects muscles in different ways, and its severity can vary from person to person. While there’s no cure, you can manage symptoms such as weakness, pain, and fatigue through medication, physical therapy, and lifestyle changes.
- #96https://arthritis.ca/about-arthritis/arthritis-types-(a-z)/types/myositis-(dermatomyositis,-polymyositis)
Myositis is a treatable disease using medications and rehabilitation. […] Most individuals respond well to treatment, except for inclusion-body myositis (IBM) which appears to be refractory to standard therapy. […] Other may experience chronic recurrence of the disease, requiring a long-term treatment. […] When the disease is under control, active physical therapy to help reduce inflammation and rebuild muscle strength can improve the patients outcome.
- #97 Myositis: All You Need to Knowhttps://www.healthline.com/health/myositis
Myositis is a progressive inflammation of the muscles that may also manifest with a skin rash. […] Symptoms of myositis may appear rapidly or gradually over time and often include muscle pain and soreness, fatigue, trouble swallowing, and difficulty breathing. […] Muscle weakness usually follows the development of the heliotrope rash. […] IBM begins with muscle weakness in the wrists, fingers, and thigh muscles. […] Like other forms of myositis, muscle weakness and a skin rash are hallmark features of JM. […] Polymyositis (PM) begins with muscle weakness in the muscles closest to the trunk and then expands to the limbs. […] Symptoms of toxic myositis are similar to those of other types of myositis. […] No cure has been found yet for myositis. Some people with severe cases of myositis may require the use of a cane, walker, or wheelchair to move independently. […] Treatment is effective for managing symptoms and preventing complications, and some people may experience partial or complete remission (symptom relief). […] Myositis is a rare autoimmune condition that often manifests with symptoms like persistent fatigue, muscle weakness, and a skin rash.
- #98 Can Myositis Be Reversed?https://advancedrheum.com/can-myositis-be-reversed/
Inclusion body myositis differs slightly from the variants listed above in that it most frequently affects areas such as the hands and knee joints. […] Myositis symptoms can look similar to other conditions, such as low vitamin D, calcium, or magnesium levels, infections, sustained alcohol consumption, or medication side effects. […] However, if you feel weak or unusually fatigued after simple activities such as walking up stairs or brushing your hair, or your muscles feel exceptionally tender or swollen without obvious relation to strenuous physical exertion, it would be wise to schedule an appointment with a doctor for an evaluation. […] While there is currently no known cure for myositis, there are treatments that can help to improve symptoms and repair damaged muscles. Often, the effects can be reversed or managed with the proper treatment plan, which might incorporate steroids in combination with a supervised exercise regimen. With early diagnosis and treatment, many people experience a good quality of life, even if the condition cant be reversed fully.
- #99 Prognosis – The Myositis Associationhttps://www.myositis.org/about-myositis/treatment-disease-management/prognosis/
Prognosis for the different forms of myositis vary greatly and often depend on the presence of other conditions, such as interstitial lung disease or certain autoantibodies. […] While inclusion body myositis is a progressive disease, life expectancy for those with IBM is usually the same as for those without the disease. In fact, IBM patients usually dont die from the disease, but from complications (often preventable) that are associated with it. Patients who develop impaired swallowing, for example, are at greater risk for aspiration (inhaling food and fluids into the lungs), which causes pneumonia and may lead to death. Similarly, injuries that occur as a result of falling, such as hip fractures and head injuries, also increase the likelihood of dying. […] For dermatomyositis, polymyositis, and necrotizing myopathy, the progression of the disease is more complicated and harder to predict. More than 95 percent of those with DM, PM, and NM are still alive more than five years after diagnosis. Many experience only one period of acute illness in their lifetime; others struggle with symptoms for years.
- #100 LIVING WITH MYOSITIS: HOW TO COPE WITH MUSCLE INFLAMMATION | Mya Carehttps://myacare.com/blog/living-with-myositis-how-to-cope-with-muscle-inflammation
The symptoms of myositis may vary depending on the type and severity of the disease. While some people may experience minor symptoms that have little impact on their quality of life, others may experience more serious symptoms that warrant medical treatment. […] The prognosis of myositis depends on a number of factors, such as the intensity and nature of the disease, the patient’s reaction to treatment, and the occurrence of any complications. For some, the disease can be debilitating and affect daily activities. Remission is documented in a few cases, although symptoms tend to return at a later date.
- #101 Myositis | Causes, symptoms, treatmenthttps://versusarthritis.org/about-arthritis/conditions/myositis/
Although people can make a good recovery, some never regain their original muscle strength or function. […] Sometimes, drug treatments dont work fully and the muscles can remain weak. […] Occasionally, myositis can affect breathing and swallowing. This may occur at the start of severe cases when the muscles used for these important tasks become weak. […] People with myositis can make a good recovery. However, some people with severe symptoms may never fully recover.
- #102 Myositis: Symptoms, Causes, Diagnosis and Treatmentshttps://www.webmd.com/a-to-z-guides/myositis-symptoms-treatments-prognosis
Most muscle pain is caused by strain injuries or ordinary illnesses, such as colds and flu, not myositis. […] If you have any symptoms of myositis, make sure you talk to your doctor. […] Because many conditions can cause muscle weakness and pain, and testing for myositis isn’t always a straightforward process, getting a proper diagnosis can take some time. […] While there’s no cure for myositis, there are ways to manage your symptoms. […] With the right treatment, myositis may go into remission, meaning your symptoms could go away entirely. […] Living with myositis can be challenging, and setbacks can happen even when you follow your doctors recommendations. […] Myositis affects muscles in different ways, and its severity can vary from person to person. While there’s no cure, you can manage symptoms such as weakness, pain, and fatigue through medication, physical therapy, and lifestyle changes.
- #103 Myositis – Harvard Healthhttps://www.health.harvard.edu/diseases-and-conditions/myositis-a-to-z
With proper treatment, most people with polymyositis or dermatomyositis eventually regain at least some muscle strength. Often, muscle strength returns to normal. Typically, inclusion body myositis does not improve with treatment. However, the illness usually progresses slowly and does not affect a person’s lifespan unless complications lead to serious illness, such as pneumonia caused by swallowing or breathing problems. Eventually, some patients need a cane to help them walk. Others require a wheelchair. […] The prognosis is very good. In most cases, symptoms subside when the drug is stopped.
- #104 Patient Basics: Myositis | 2 Minute Medicinehttps://www.2minutemedicine.com/patient-basics-myositis/
With proper treatment, most people with polymyositis or dermatomyositis eventually regain at least some muscle strength. Often, muscle strength returns to normal. Typically, inclusion body myositis does not improve with treatment. However, the illness usually progresses slowly and does not affect a personâs lifespan unless complications lead to serious illness, such as pneumonia caused by swallowing or breathing problems. Eventually, some patients need a cane to help them walk. Others require a wheelchair.
- #105 Myositis: Types, Symptoms, Causes, Diagnosis and Treatment Optionshttps://www.apollohospitals.com/diseases-and-conditions/myositis-types-symptoms-causes-diagnosis-and-treatment
The symptoms of inclusion body myositis are as follows: Difficulty using hands and fingers to perform precise and mundane tasks, such as buttoning a shirt or tying a shoelace, Gripping small objects, Troubled walking or standing, Swallowing, Frequently tripping, falling, and loss of balance, Difficulty in getting up from a seated position, Weakness in the muscle, Pain in the muscle and swallowing issues, Decreased deep tendon reflexes. […] The following are the symptoms of dermatomyositis: Dry, scaly, or rough skin with rashes, Presence of lumps over the knuckles, elbows, and knees that are often raised and scaly and easily break out, Difficult getting up from a seated position, Fatigue, Weakness in the muscle present in the neck, hip, back, and shoulders, Troubled swallowing, Hoarse voice, Pain in the muscle and inflammation of the joint, Solidified lumps of calcium under the skin, Abnormalities in the nail bed, Weight loss, Arrhythmia, Gastrointestinal ulcers.
- #106 Myositis | Causes, symptoms, treatmenthttps://versusarthritis.org/about-arthritis/conditions/myositis/
Although people can make a good recovery, some never regain their original muscle strength or function. […] Sometimes, drug treatments dont work fully and the muscles can remain weak. […] Occasionally, myositis can affect breathing and swallowing. This may occur at the start of severe cases when the muscles used for these important tasks become weak. […] People with myositis can make a good recovery. However, some people with severe symptoms may never fully recover.
- #107 Myositis – Harvard Healthhttps://www.health.harvard.edu/diseases-and-conditions/myositis-a-to-z
With proper treatment, most people with polymyositis or dermatomyositis eventually regain at least some muscle strength. Often, muscle strength returns to normal. Typically, inclusion body myositis does not improve with treatment. However, the illness usually progresses slowly and does not affect a person’s lifespan unless complications lead to serious illness, such as pneumonia caused by swallowing or breathing problems. Eventually, some patients need a cane to help them walk. Others require a wheelchair. […] The prognosis is very good. In most cases, symptoms subside when the drug is stopped.
- #108 Myositis Guide: Causes, Symptoms and Treatment Optionshttps://www.drugs.com/health-guide/myositis.html
The duration of myositis depends on the type: Idiopathic inflammatory myopathies: These are typically chronic, with symptoms persisting for months or years. Treatment may lead to improvement, but some cases of inclusion body myositis do not respond to therapy. […] The outlook for myositis varies: Idiopathic inflammatory myopathies: Many people respond well to treatment and regain muscle strength, though inclusion body myositis often does not improve significantly with treatment.
- #109 Myositis: Causes & Symptoms of Autoimmune Muscle Diseases – Dr. Axehttps://draxe.com/health/myositis/
There is no cure for myositis, although most people with the disease have a good prognosis. Polymyositis and dermatomyositis are highly treatable and respond well to medication. Juvenile myositis and necrotizing autoimmune myopathy can also go away completely with therapy. However, many people may have flares of symptoms or may find their symptoms return when they stop treatment. Others, particularly those with inclusion body myositis, may not respond to any treatment.
- #110 What are the Symptoms, Causes, and Treatment for Myositis?https://familymedicineaustin.com/myositis-symptoms-causes-and-prognosis/
Although some people recover fully, others never regain their normal muscular power or function. […] Myositis has no known absolute treatment though symptoms could be relieved. Myositis, if left untreated, can result in disability and even death. Some people, however, can effectively control their symptoms. Some people may even have partial or total remission.
- #111 Inclusion body myositis (IBM) – Autoimmune Associationhttps://autoimmune.org/disease-information/inclusion-body-myositis-ibm/
Most people with IBM progress to disability over a period of years. In general, the older a person is when IBM begins, the more rapid the progression of the condition. Most people need assistance with basic daily activities within 15 years, and some people will need to use a wheelchair. […] Lifespan is thought to be normal, but severe complications (e.g. aspiration pneumonia) can lead to loss of life.
- #112 Prognosis – The Myositis Associationhttps://www.myositis.org/about-myositis/treatment-disease-management/prognosis/
Prognosis for the different forms of myositis vary greatly and often depend on the presence of other conditions, such as interstitial lung disease or certain autoantibodies. […] While inclusion body myositis is a progressive disease, life expectancy for those with IBM is usually the same as for those without the disease. In fact, IBM patients usually dont die from the disease, but from complications (often preventable) that are associated with it. Patients who develop impaired swallowing, for example, are at greater risk for aspiration (inhaling food and fluids into the lungs), which causes pneumonia and may lead to death. Similarly, injuries that occur as a result of falling, such as hip fractures and head injuries, also increase the likelihood of dying. […] For dermatomyositis, polymyositis, and necrotizing myopathy, the progression of the disease is more complicated and harder to predict. More than 95 percent of those with DM, PM, and NM are still alive more than five years after diagnosis. Many experience only one period of acute illness in their lifetime; others struggle with symptoms for years.
- #113 Prognosis – The Myositis Associationhttps://www.myositis.org/about-myositis/treatment-disease-management/prognosis/
Of those who die early in the disease course, the most frequent cause is not the myositis itself, but infection due to suppressed immunity as a result of treatment. […] Complications contributing to mortality include myositis-associated cancer, dysphagia (trouble swallowing), interstitial lung disease, and heart problems.
- #114 Polymyositis – Adult – UF Healthhttps://ufhealth.org/conditions-and-treatments/polymyositis-adult
Polymyositis and dermatomyositis are rare inflammatory diseases. These diseases lead to muscle weakness, swelling, tenderness, and tissue damage. […] Muscle weakness and tenderness can be signs of polymyositis. Common symptoms include: Muscle weakness in the shoulders and hips. This can make it hard to raise the arms over the head, get up from a sitting position, or climb stairs. […] You may also have: Fatigue, Fever, Joint pain, Loss of appetite, Morning stiffness, Weight loss, Skin rash on the back of the fingers, on the eyelids, or on the face. […] Response to treatment varies, based on the complications. As many as 1 in 5 people may die within 5 years of developing the condition. […] The outlook for people with lung disease with the anti-MDA-5 antibody is poor despite current treatment. […] In adults, death may result from: Malnutrition, Pneumonia, Respiratory failure, Severe, long-term muscle weakness. The major causes of death are cancer and lung disease.
- #115 Myositis: Symptoms, Causes, Diagnosis, and Treatmenthttps://www.verywellhealth.com/myositis-overview-4778444
Currently, there is no cure for myositis. However, the disease can be managed, and medicinal treatment is helpful for reducing inflammation and keeping muscle weakness from getting worse. […] The outlook for most types of myositis can be good with proper treatment. But if left untreated, myositis can result in disability or death.
- #116 About Myositis – Myositis Association Australiahttps://myositis.org.au/myositis/about-myositis/
Myositis is a group of rare conditions where the bodys immune system turns against itself and destroys healthy muscle tissue instead of building new muscle tissue, leading to muscle weakness and other systemic symptoms. […] Once gone the muscle cannot be regenerated (although there are research studies working on this) and over time this can result in a progressive and cumulative loss of muscle that leads to a state of weakness and disability. […] Symptoms can appear gradually, over a period of months or years or may develop rapidly within days or weeks. […] Generally, Myositis can cause significant muscle loss with comparable decline in strength, dexterity and mobility over time. In extreme cases, Myositis can be fatal when the heart and lung muscles are involved.
- #117 Myositis: Muscle Inflammation | Inflammatory Myopathy | HSShttps://www.hss.edu/condition-list_myositis.asp
Symptoms of myositis include muscle inflammation, weakness, fatigue and, in some people, muscle pain. But it can affect the whole body: Some patients can have other symptoms such as arthritis in the hands that resembles those in rheumatoid arthritis, lung inflammation that causes coughing or shortness of breath, and skin inflammation or rashes. Each patients disease experience and mix of symptoms is unique. Some cases are very mild, while others are severe. […] The most common symptom of myositis is muscle weakness. The weakness often develops slowly, and can be subtle at first, influencing patients ability to do certain activities. They can have trouble doing tasks that require having their arms held above their head things like washing, brushing, or blow drying their hair, reaching items on high shelves, or hanging up an overcoat can be hard. Additionally, they can have trouble getting up from low chairs, getting out of a car, or climbing steps. Patients can trip and be unable to catch themselves or be unable to get up from the floor after falling. Sometimes, in the most severe cases, the muscles of the throat or diaphragm can weaken, leading to trouble swallowing or shortness of breath.
- #118 Polymyositis – What is it? How is it treated? – Myositis UKhttps://www.myositis.org.uk/myositis-info/conditions/polymyositis/
Polymyositis (PM) is a form of myositis a rare disease that causes muscle weakness and inflammation in adults. […] The main symptoms are weakness and inflammation of the muscles (poly means many, myo means muscle, and itis means inflammation). The muscular weakness may be progressive and can be severely disabling. […] The main symptoms of polymyositis are weak and painful muscles, tiredness and feelings of depression. Some people may also have joint pains. […] Some may have the disease for months or even years before it is realised, but most notice within weeks if they have developed muscular weakness. […] The weakness results in difficulty in walking, lifting arms and getting up from the sitting and lying down positions. There may even be some trouble in swallowing and the voice may become nasal or deeper in quality.
- #119 Myositis Causes, Symptoms, and Treatments | UPMChttps://www.upmc.com/services/rheumatology/conditions/myositis
Myositis can affect how you walk, move your arms and hands, swallow, and breathe. […] Myositis can cause problems in muscle groups and other symptoms throughout the body. This includes muscles in the arms and legs as well as the muscles that help you swallow. Myositis can also attack the heart and lungs, causing shortness of breath. […] Myositis symptoms and complications vary by type and severity. They may come on all of a sudden or slowly get worse over time. […] Myositis symptoms and complications include: A rash on your face, knuckles, or elsewhere on the body. […] Breathing problems (if it’s attacking the lung tissue). […] Weakness that makes it hard to lift your arms. […] No, there’s no cure for myositis, but early treatment can prevent further muscle weakness.
- #120 Myositis | Arthritis Foundationhttps://www.arthritis.org/diseases/myositis
Dermatomyositis causes patchy purple or red rashes on the face, eyelids, elbows, knees, toes, chest or back. These rashes can appear before, after or during symptoms of muscle weakness. […] Weakness of the throat muscles can cause trouble swallowing, called dysphagia. About one-third of people with myositis have trouble swallowing. […] Lung tissue in people with myositis can become scarred, which causes breathing problems. About 30 to 40 percent of people with myositis have some form of lung disease.
- #121https://arthritis.ca/about-arthritis/arthritis-types-(a-z)/types/myositis-(dermatomyositis,-polymyositis)
Myositis typically affects the large muscles of the arms and legs on both sides of the body, but can also affect muscles associated with swallowing or breathing, and in rare cases can affect the heart as well. […] With treatment, patients can achieve periods of no active symptoms (remission), but the disease tends to recur with periods of active symptoms (flare). […] Muscle Weakness: Usually, the main symptom of myositis is muscle weakness. At the onset of the disease it generally affects the thighs and hips. If you have myositis, you may have difficulty climbing stairs or rising from low surfaces. The distance you are able to walk may eventually be limited because your muscles get too tired. […] If myositis affects your neck, chest and abdomen muscles it may be hard to lift your head from a pillow or get out of bed. Polymyositis can also cause you to have trouble swallowing or talking, though these are less common results of the disease.
- #122 How Do I Explain Myositis? – Myositis Support and Understandinghttps://understandingmyositis.org/explaining-myositis/
Myositis affects each person differently including changing symptoms, abilities, therapies and side effects. […] Myositis is a chronic disease and you will have Myositis for the rest of your life, although some do achieve remission, or as we like to call it disease stability. […] Myositis causes a variety of symptoms and affects each person differently. Muscle weakness, muscle pain, uncomfortable-itchy-painful skin rashes, debilitating fatigue, trouble breathing, achy joints, heart arrhythmias, and many other symptoms makes Myositis a very complex disease. […] Myositis is unpredictable. Some may reach remission (symptoms stabilize or improve) and some may battle ongoing disease and/or periods of flares (symptoms worsen). The unpredictability can be frustrating for us as patients and for family members and friends. […] Grieving the loss of our normal lives is a normal process that can take time. When you add disease progression, you may find you are going through the process of grieving many times during your life such as when you lose another ability. Take the time to grieve.
- #123 Myositis: Symptoms, Causes & Treatmenthttps://my.clevelandclinic.org/health/diseases/24170-myositis
Theres no cure for myositis, but in most cases, treatment can put it into remission. Most people with myositis have it for the rest of their lives. […] Some cases of myositis can be fatal. Around 5% of people with dermatomyositis die within a year of their diagnosis. This is why its important to get your symptoms examined by a healthcare provider as soon as you notice them. […] Myositis is chronic muscle inflammation caused by your immune system attacking muscles throughout your body. Your symptoms will come and go in episodes, probably for the rest of your life. Even though theres no cure for myositis, your healthcare provider will help you find treatments and physical therapy exercises that will manage your symptoms.
- #124 Myositis: Symptoms, Causes, Diagnosis and Treatmentshttps://www.webmd.com/a-to-z-guides/myositis-symptoms-treatments-prognosis
Most muscle pain is caused by strain injuries or ordinary illnesses, such as colds and flu, not myositis. […] If you have any symptoms of myositis, make sure you talk to your doctor. […] Because many conditions can cause muscle weakness and pain, and testing for myositis isn’t always a straightforward process, getting a proper diagnosis can take some time. […] While there’s no cure for myositis, there are ways to manage your symptoms. […] With the right treatment, myositis may go into remission, meaning your symptoms could go away entirely. […] Living with myositis can be challenging, and setbacks can happen even when you follow your doctors recommendations. […] Myositis affects muscles in different ways, and its severity can vary from person to person. While there’s no cure, you can manage symptoms such as weakness, pain, and fatigue through medication, physical therapy, and lifestyle changes.
- #125 Myositis | UCSF Neuromuscular Divisionhttps://neuromuscular.ucsf.edu/myositis
Myositis is a rare autoimmune disease that affects the muscles and causes inflammation, weakness, and fatigue. […] Symptoms of myositis typically develop slowly over time and can include difficulty climbing stairs, rising from a chair, or lifting objects. Patients may also experience muscle pain, joint pain, and a rash on the face or chest in the case of dermatomyositis. […] Although there is no cure for myositis, treatment can help manage symptoms and slow the progression of the disease. Early diagnosis and treatment is important in order to prevent muscle damage and improve outcomes for patients.
- #126 Myositis: Causes & Symptoms of Autoimmune Muscle Diseases – Dr. Axehttps://draxe.com/health/myositis/
This type of myositis is rare and causes weakness in the upper and lower body. The onset of symptoms can be sudden, rather than gradual, and can become quite severe within just a few days or weeks. Other symptoms may include weight loss, muscle pain and fatigue. […] Without proper treatment, most forms of myositis can progress to cause trouble swallowing, walking and taking care of yourself. Do not delay or avoid medical treatment or you may risk permanent muscle damage, falls, broken bones, malnutrition and other serious health complications. […] Myositis is a set of inflammatory muscle disorders. In most cases, the diseases cause muscle weakness, fatigue, inflammation and a gradual worsening in symptoms. Without treatment, the diseases can make it hard to walk, swallow and do many activities of daily living.