Wypadanie włosów
Epidemiologia
Wypadanie włosów (alopecia) stanowi istotny problem zdrowotny o zróżnicowanej etiologii, obejmujący głównie łysienie androgenowe (AGA), łysienie plackowate (AA) oraz łysienie bliznowaciejące. AGA dotyka około 50% populacji mężczyzn i kobiet, z częstością występowania u mężczyzn rasy kaukaskiej sięgającą 30-50% w wieku 30-50 lat, a u kobiet wzrastającą do 38% po 70. roku życia. Łysienie plackowate ma punktową częstość występowania 0,16-0,21% i ryzyko rozwoju w ciągu życia około 2%, z szczytem zachorowań między 25 a 29 rokiem życia. Łysienie bliznowaciejące stanowi około 7% przypadków łysienia, jednak dane epidemiologiczne są ograniczone z powodu braku ustalonych kryteriów diagnostycznych. Występują istotne różnice etniczne w rozpowszechnieniu i przebiegu chorób, np. AGA jest czterokrotnie częstsze u mężczyzn rasy kaukaskiej niż afrokaraibskiej, a łysienie plackowate jest bardziej powszechne u osób azjatyckich. Wypadanie włosów wiąże się z istotnym obciążeniem psychospołecznym oraz współistnieniem chorób autoimmunologicznych i metabolicznych, co podkreśla potrzebę kompleksowej diagnostyki i monitorowania pacjentów.
- Epidemiologia wypadania włosów – przegląd ogólny
- Łysienie androgenowe (androgenetic alopecia)
- Kobiece łysienie androgenowe
- Łysienie plackowate (alopecia areata)
- Łysienie bliznowaciejące (scarring alopecia)
- Zróżnicowanie etniczne w wypadaniu włosów
- Monitorowanie i nadzór epidemiologiczny łysienia
- Globalne systemy nadzoru epidemiologicznego
- Wyzwania w monitorowaniu epidemiologicznym
- Obszary wymagające poprawy w monitorowaniu epidemiologicznym
- Choroby współistniejące i ich monitorowanie w łysieniu
- Choroby autoimmunologiczne współistniejące z łysieniem
- Zaburzenia psychiczne współistniejące z łysieniem
- Zaburzenia metaboliczne współistniejące z łysieniem
- Przyszłe kierunki badań i nadzoru nad łysieniem
Epidemiologia wypadania włosów – przegląd ogólny
Wypadanie włosów (alopecia) stanowi istotny problem zdrowotny, który dotyka znaczną część populacji na całym świecie. Najnowsze dane epidemiologiczne wskazują, że problem ten dotyczy ponad 56 milionów osób na świecie, przy czym w samej Wielkiej Brytanii szacuje się, że około 6,5 miliona mężczyzn i 8 milionów kobiet zmaga się z różnymi formami wypadania włosów.1 Wypadanie włosów można podzielić na dwie główne kategorie: niebliznowaciejące (73% przypadków) oraz bliznowaciejące (27% przypadków), co potwierdzają wyniki wieloośrodkowych badań retrospektywnych z 2019 roku.2
Znaczenie problemu podkreśla nie tylko jego rozpowszechnienie, ale również istotny wpływ psychospołeczny na jakość życia pacjentów.3 Wpływ wypadania włosów na samoocenę, obraz ciała i ogólne samopoczucie jest znaczący, co sprawia, że gotowość dermatologów do prawidłowej oceny tego częstego problemu jest niezwykle ważna.4 Każdy typ łysienia charakteryzuje się własną unikalną etiologią, epidemiologią, prezentacją kliniczną, wynikami trichoskopowymi oraz badaniami laboratoryjnymi.5
Łysienie androgenowe (androgenetic alopecia)
Łysienie androgenowe (androgenetic alopecia, AGA) jest najczęstszym typem wypadania włosów o genetycznie uwarunkowanym podłożu, wynikającym z nadmiernej reakcji na androgeny. Dotyka około 50% mężczyzn i kobiet i charakteryzuje się postępującą utratą włosów terminalnych na skórze głowy po okresie dojrzewania.6 Jego rozpowszechnienie szacuje się na około 0,22% wszystkich populacji na świecie, z istotną zmiennością w zależności od płci i rasy.7
W Stanach Zjednoczonych łysienie androgenowe dotyka około 50 milionów mężczyzn i 30 milionów kobiet.8 W populacji europejskiej, szczególnie wśród osób rasy kaukaskiej, częstość występowania AGA u mężczyzn jest szacowana na około 30% w wieku 30 lat, 40% w wieku 40 lat oraz 50% w wieku 50 lat.9 W badaniu populacyjnym przeprowadzonym w Indiach, obejmującym 1005 osób, wykazano 58% częstość występowania AGA u mężczyzn w wieku 30-50 lat.10
Zgodnie z badaniami epidemiologicznymi, rasa kaukaska jest najbardziej dotknięta AGA, następnie Azjaci i Afroamerykanie, a na końcu rdzenni Amerykanie i Inuici.11 Około 50 000 na 100 000 mężczyzn rasy kaukaskiej ma łysienie androgenowe do 50. roku życia, a liczba ta wzrasta do około 80 000 na 100 000 do 70. roku życia.12
Kobiece łysienie androgenowe
Kobiece łysienie androgenowe dotyka około 30 milionów kobiet w Stanach Zjednoczonych.13 Częstość występowania u kobiet wynosi około 19% według badania Norwooda przeprowadzonego na populacji 1006 pacjentów rasy kaukaskiej.14 W badaniu chińskiej populacji częstość występowania wynosiła tylko 6,0%, a koreańskie badanie wykazało podobnie niższą częstość występowania na poziomie 5,6%, co sugeruje, że podobnie jak u mężczyzn, częstość występowania jest niższa w rasach orientalnych w porównaniu z rasą kaukaską.15
Częstość występowania łysienia androgenowego u kobiet wyraźnie rośnie po menopauzie, co świadczy o możliwym związku ze zmniejszającym się poziomem hormonów żeńskich.16 Według jednego z autorów, może to dotyczyć nawet 75% kobiet powyżej 65. roku życia.17 W Wielkiej Brytanii u 6% kobiet w wieku poniżej 50 lat zdiagnozowano FPHL, co wzrasta do 38% u osób w wieku 70 lat i powyżej.18
W Australii, skorygowana względem wieku częstość występowania umiarkowanego do ciężkiego FPHL wśród dorosłych kobiet pochodzenia europejskiego wynosi 32%. Przekłada się to na 800 000 kobiet cierpiących z powodu umiarkowanego do ciężkiego FPHL.19
Łysienie plackowate (alopecia areata)
Łysienie plackowate (alopecia areata, AA) to autoimmunologiczna choroba skóry objawiająca się niebliznowaciejącym wypadaniem włosów. Występuje na całym świecie, ale częstość występowania i rozpowszechnienie różnią się geograficznie i w podpopulacjach.20 Badania epidemiologiczne ze Stanów Zjednoczonych i Wielkiej Brytanii oszacowały ogólną częstość występowania między 0,21 a 0,26 na 1000 pacjento-lat (około 1 nowy przypadek na 4000 osób rocznie), a punktową częstość występowania na 0,16-0,21% (około 1 na 500 ma aktywne łysienie plackowate).21
Skumulowana częstość występowania w ciągu całego życia (ryzyko w ciągu całego życia) wynosi około 2% (czyli 1 na 50 osób rozwinie łysienie plackowate w pewnym momencie życia).22 Łysienie plackowate jest najczęstszym zaburzeniem autoimmunologicznym i drugim najczęstszym zaburzeniem utraty włosów po łysieniu androgenowym.23
W duńskim badaniu kohortowym zaobserwowano ogólną częstość występowania AA leczonego w szpitalu na 2,62 na 100 000 osobo-lat (95% CI 2,53-2,72) oraz ogólne rozpowszechnienie w 2016 roku na 71,7 (95% CI 69,4-74,1) na 100 000 osób. Częstość występowania i rozpowszechnienie zarówno podtypów AT/AU, jak i nie-AT/AU zwiększały się z czasem.24
Badanie oparte na populacji Wielkiej Brytanii wykazało, że 1 na 170 osób w badanej populacji miało aktywne łysienie plackowate lub miało je w przeszłości. Łysienie plackowate było nieco częstsze u kobiet niż u mężczyzn. Może rozpocząć się w każdym wieku, ale szczyt występowania jest między 25 a 29 rokiem życia.25 Łysienie plackowate jest również częstsze u osób mieszkających na obszarach miejskich w porównaniu z obszarami wiejskimi oraz u osób mieszkających na obszarach społecznie upośledzonych.26
| Populacja | Częstość występowania AA | Szczyt zachorowań | Ryzyko w ciągu życia |
|---|---|---|---|
| Populacja ogólna | 0,1-0,2% (punktowa) | 20-30 lat | ~2% |
| Wielka Brytania | 1 na 170 osób | 25-29 lat | – |
| USA i UK (badania epidemiologiczne) | 0,21-0,26 na 1000 pacjento-lat | – | ~2% |
| Dania (leczeni szpitalnie) | 2,62 na 100 000 osobo-lat | – | – |
| Dzieci | – | 60% przed 20 r.ż. | – |
Łysienie bliznowaciejące (scarring alopecia)
Łysienie bliznowaciejące (scarring alopecia) to rzadki rodzaj wypadania włosów, w którym stan zapalny niszczy mieszki włosowe i powoduje tworzenie się tkanki bliznowatej w ich miejscu.27 W populacji osób z łysieniem częstość występowania łysienia bliznowaciejącego szacuje się na około 7%.28
Brak jest dużych badań epidemiologicznych opartych na dowodach, które przedstawiałyby epidemiologię liszaja płaskiego mieszkowego (lichen planopilaris), centralnego odśrodkowego łysienia bliznowaciejącego (central centrifugal cicatricial alopecia) lub pseudopelade/” title=”pseudopelade” class=”to-tag” data-termid=”32760″>pseudopelade w populacji ogólnej.29 Badania populacyjne wskazują na częstość występowania łysienia z pociągania (traction alopecia) na poziomie 17,1% u afrykańskich uczennic (6-21 lat) oraz 31,7% u kobiet (18-86 lat).30
W badaniu przeprowadzonym w indyjskiej klinice dermatologicznej zdiagnozowano pierwotne łysienie bliznowaciejące u 61 pacjentów spośród 66 370 pacjentów, co daje częstość występowania 0,09% (61/66 370). Najczęstszym podtypem był liszaj płaski mieszkowy (LPP) (39,6%, 21/53). Średni wiek pacjentów wynosił 30,9 ± 8,1 lat (zakres 1-50 lat), przy czym ponad połowa (52,8%, 28/53) należała do grupy wiekowej 30-39 lat. Ogólnie zaobserwowano przewagę płci żeńskiej (M:F 24:29).31
Zróżnicowanie etniczne w wypadaniu włosów
Epidemiologia wypadania włosów wykazuje znaczne zróżnicowanie etniczne. W przypadku łysienia androgenowego, mężczyźni rasy kaukaskiej są dotknięci cztery razy częściej niż osoby pochodzenia afrokaraibskiego. Łysienie ma tendencję do późniejszego występowania i wolniejszego postępu u mężczyzn pochodzenia azjatyckiego.32
Łysienie androgenowe również wykazuje zmienność etniczną u kobiet, będąc mniej powszechnym u kobiet pochodzenia orientalnego.33 W przypadku łysienia plackowatego, badania wskazują, że osoby pochodzenia azjatyckiego mają najwyższe ryzyko, z prawie 6 przypadkami na 100 osób, w porównaniu do mniej niż 2 przypadków na 100 osób wśród osób rasy białej.34
Centralne odśrodkowe łysienie bliznowaciejące jest uważane za dominujące u Afroamerykanów, podczas gdy liszaj płaski mieszkowy występuje głównie u pacjentów o jaśniejszej skórze.35 Łysienie z pociągania najczęściej obserwuje się w populacji afroamerykańskiej ze względu na praktykę stylizacji włosów w ciasne warkocze lub stosowanie chemicznych prostowników do włosów.36
Badanie przeprowadzone wśród Afroamerykanek wykazało, że 47,6% kobiet zgłosiło utratę włosów na koronie lub czubku głowy. Mimo powszechności problemu, większość respondentek (81,4%) nigdy nie konsultowała się z lekarzem w sprawie wypadania włosów.37
Monitorowanie i nadzór epidemiologiczny łysienia
Monitorowanie epidemiologiczne łysienia ma kluczowe znaczenie dla zrozumienia trendów, czynników ryzyka i skuteczności interwencji w różnych populacjach. Pomimo postępów w zrozumieniu epidemiologii łysienia plackowatego, aktualne dane epidemiologiczne pozwalają zrozumieć wzorce na poziomie populacyjnym, ale wciąż brakuje pełnego zrozumienia różnic między konkretnymi pacjentami w odniesieniu do ciężkości choroby, odpowiedzi na terapię i ryzyka nawrotu.38
Globalne systemy nadzoru epidemiologicznego
Nadzór nad łysieniem na skalę globalną jest prowadzony przez różne inicjatywy badawcze, w tym przez Globalny Projekt Badania Obciążenia Chorobami (Global Burden of Disease Study), który szacuje DALY (lata życia skorygowane niesprawnością) dla łysienia plackowatego na 1 332 800, czyli ważone 0,035. Jednak dane te mogą niedoszacowywać rzeczywistej częstości występowania w populacji i obciążenia chorobą ze względu na pacjentów z łysieniem plackowatym, którzy nie zgłaszają się po pomoc.39
Raporty epidemiologiczne, takie jak „Androgenetic Alopecia – Epidemiology Forecast – 2032”, dostarczają szczegółowych informacji na temat historycznych i bieżących populacji pacjentów oraz prognozowanych trendów dla siedmiu głównych rynków (7MM: USA, Niemcy, Hiszpania, Włochy, Francja, Wielka Brytania i Japonia).40 Według tych szacunków, całkowita liczba przypadków łysienia androgenowego w 7MM wynosiła ponad 194 000 000 w 2021 roku, przy czym UE4 i Wielka Brytania miały najwyższą populację pacjentów.41
Podobnie, raport „Alopecia Areata – Epidemiology Forecast to 2028” opracowany przez GlobalData prognozuje wzrost zdiagnozowanych przypadków zachorowań na łysienie plackowate w 7MM ze 156 056 w 2018 roku do 157 883 w 2028 roku, ze średnią roczną stopą wzrostu (AGR) 0,12% w okresie prognozy. USA będą miały najwyższą liczbę zdiagnozowanych przypadków zachorowań na łysienie plackowate wśród 7MM, podczas gdy Hiszpania będzie miała najniższą.42
Wyzwania w monitorowaniu epidemiologicznym
Jednym z głównych wyzwań w monitorowaniu epidemiologicznym łysienia jest brak ustanowionych kryteriów diagnostycznych. W przypadku łysienia bliznowaciejącego, badania dotyczące częstości występowania są nadal niewystarczające, a częściową przeszkodą w produkcji takich danych jest właśnie brak dobrze ustalonych kryteriów diagnostycznych.43
Innym wyzwaniem jest różnorodność metodologii stosowanych w badaniach epidemiologicznych. Na przykład, badanie duńskie przeprowadzone na populacji pacjentów leczonych w szpitalu wykazało częstość występowania łysienia plackowatego na poziomie 2,62 na 100 000 osobo-lat, co jest około 10 razy niższe niż szacunki oparte na danych z Wielkiej Brytanii, USA i Korei Południowej. Ta różnica prawdopodobnie wynika z potencjalnie dużej liczby pacjentów z łysieniem plackowatym diagnozowanych i leczonych w praktyce ogólnej, a zatem nie uwzględnionych w badaniu.44
Ważnym aspektem monitorowania jest również ocena ryzyka genetycznego. Badania genomu wykazały, że łysienie androgenowe jest jedną z najbardziej dziedzicznych cech złożonych, dla której jesteśmy w stanie wyjaśnić prawie dwie piąte dziedziczności za pomocą zaledwie 71 loci. Badania nad genomem wskazują, że łysienie androgenowe ma h2SNP (odziedziczalność SNP) na poziomie 94%, co sugeruje, że jest to bardziej cecha poligenetyczna niż złożona, z bardzo małym komponentem środowiskowym.45
Obszary wymagające poprawy w monitorowaniu epidemiologicznym
Istnieje kilka obszarów, w których nadzór epidemiologiczny nad łysieniem mógłby zostać ulepszony. Jednym z nich jest potrzeba lepszego zrozumienia wczesnej i bardziej agresywnej terapii łysienia plackowatego w zapobieganiu rozwojowi chorób współistniejących, zarówno psychiatrycznych, jak i innych.46
Kolejnym obszarem jest lepsze zrozumienie różnic międzypłciowych w epidemiologii łysienia. Na przykład, pacjenci płci męskiej mogą być częściej diagnozowani w dzieciństwie, podczas gdy kobiety są bardziej skłonne do zgłaszania się w okresie dojrzewania i mają większe współistniejące zaangażowanie paznokci lub współistniejące choroby autoimmunologiczne.47
Istnieje również potrzeba lepszego zrozumienia czynników ryzyka i współistniejących chorób. Łysienie plackowate jest związane z atopią i wieloma chorobami autoimmunologicznymi, w tym bielactwem i zaburzeniami tarczycy.48 Podobnie, u osób z łysieniem androgenowym warto przeprowadzić badania przesiewowe w kierunku metabolicznych czynników ryzyka sercowo-naczyniowego, ponieważ jedno badanie wykazało, że łysienie typu wzorca było niezależnym predyktorem śmiertelności z powodu cukrzycy i choroby serca zarówno u kobiet, jak i mężczyzn.49
Choroby współistniejące i ich monitorowanie w łysieniu
Wypadanie włosów często współistnieje z innymi schorzeniami, co podkreśla znaczenie systematycznego monitorowania i kompleksowej opieki nad pacjentami z różnymi typami łysienia. Zrozumienie tych związków jest kluczowe dla opracowania skutecznych strategii zarządzania i leczenia.
Choroby autoimmunologiczne współistniejące z łysieniem
Łysienie plackowate często współistnieje z innymi chorobami autoimmunologicznymi. Osoby z łysieniem plackowatym mają nieco wyższe niż przeciętne ryzyko rozwoju innych chorób autoimmunologicznych, takich jak choroby tarczycy, niedokrwistość złośliwa i bielactwo/” title=”bielactwo” class=”to-tag” data-termid=”21215″>bielactwo.50 Około 20% osób, u których rozwija się łysienie plackowate, ma dotkniętego nim krewnego; ryzyko jest zwiększone szczególnie, jeśli krewny jest członkiem najbliższej rodziny i jeśli osoba ta zachorowała przed 30. rokiem życia.51
Osoby z zespołem Downa lub autoimmunologicznym zespołem wielogruczołowym typu 1 są również bardziej narażone na rozwój tej choroby, podobnie jak osoby dotknięte innymi schorzeniami autoimmunologicznymi, takimi jak choroba trzewna, pewne choroby tarczycy, toczeń rumieniowaty, łuszczyca, reumatoidalne zapalenie stawów, cukrzyca typu 1 i bielactwo.52 Łysienie plackowate jest również związane ze zwiększonym ryzykiem chorób siatkówki, w tym odwarstwienia siatkówki, okluzji naczyń siatkówki i retinopatii.53
Zaburzenia psychiczne współistniejące z łysieniem
Wypadanie włosów może mieć istotny wpływ psychospołeczny na jakość życia pacjentów. Łysienie plackowate prowadzi do obniżonej jakości życia u połowy cierpiących na nią osób i jest związane z około 70% częstością występowania zaburzeń psychicznych w ciągu całego życia, najczęściej depresji, lęku i zaburzeń adaptacyjnych.54
Utrata włosów może być emocjonalnym doświadczeniem i może być trudno rozmawiać o tym z innymi. Dzielenie się uczuciami z systemem wsparcia i dermatologiem może pomóc pacjentom zarządzać wpływem choroby na codzienne życie.55
Łysienie androgenowe, mimo że często uważane za stosunkowo niewielki problem dermatologiczny, wpływa na samoocenę i jest znaczącym czynnikiem przyczyniającym się do lęku i depresji u niektórych mężczyzn.56
Zaburzenia metaboliczne współistniejące z łysieniem
Istnieją dowody na związek między łysieniem androgenowym a zaburzeniami metabolicznymi. Badania przesiewowe w kierunku metabolicznych czynników ryzyka sercowo-naczyniowych są przydatne u pacjentów z łysieniem wzorczastym. Jedno badanie wykazało, że łysienie wzorczaste było niezależnym predyktorem śmiertelności z powodu cukrzycy i choroby serca zarówno u kobiet, jak i mężczyzn.57
Żeńskie łysienie androgenowe może być pierwszą skargą wskazującą na hiperandrogenizm/” title=”hiperandrogenizm” class=”to-tag” data-termid=”32764″>hiperandrogenizm, dysfunkcję tarczycy lub przewlekłą dietę niedoborową. Szczegółowy wywiad z odpowiednimi badaniami laboratoryjnymi w celu wykrycia związanych chorób sercowo-naczyniowych, nadciśnienia tętniczego i zespołu metabolicznego jest wskazany.58
Przyszłe kierunki badań i nadzoru nad łysieniem
Badania nad łysieniem stale ewoluują, a naukowcy dążą do lepszego zrozumienia mechanizmów leżących u podstaw różnych typów wypadania włosów oraz opracowania skuteczniejszych terapii. Przyszłe kierunki badań i nadzoru obejmują:
- Badania geneonomiczne mające na celu identyfikację genetycznych predyktorów ciężkiego wypadania włosów, co może pomóc w przewidywaniu prawdopodobieństwa wystąpienia ciężkiego łysienia u mężczyzn i dostarczyć nowych celów dla rozwoju leków do leczenia łysienia.59
- Badania nad inhibitorami JAK (kinazy Janusa), które mogą mieć szerokie zastosowanie w wielu formach wypadania włosów, w oparciu o ich mechanizm działania zarówno w mieszku włosowym, jak i komórkach immunologicznych.60
- Badania nad wpływem wczesnej i bardziej agresywnej terapii łysienia plackowatego na zapobieganie rozwojowi chorób współistniejących, zarówno psychiatrycznych, jak i innych.61
- Doskonalenie kryteriów diagnostycznych dla różnych typów łysienia, szczególnie łysienia bliznowaciejącego, w celu poprawy dokładności danych epidemiologicznych.62
- Badania nad wpływem czynników środowiskowych, takich jak styl życia, stres i dieta, na ryzyko i ciężkość łysienia.63
Mimo znacznych postępów w zrozumieniu epidemiologii i biologii łysienia, wciąż istnieje wiele wyzwań w opracowaniu skutecznych terapii. Większość obecnie dostępnych terapii tylko zarządza wypadaniem włosów, zamiast być trwałym rozwiązaniem. Istniejące leki stosowane w leczeniu wypadania włosów mają ograniczoną skuteczność i wymagają ciągłego stosowania, aby korzyści z leczenia utrzymywały się.64
Przyszłe badania powinny skupić się na lepszym zrozumieniu, jak kontrolowany jest cykl wzrostu włosów, i na celowaniu w przyczynę wypadania włosów zamiast leczenia objawów, co z kolei może prowadzić do mniejszej liczby skutków ubocznych.65
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Materiały źródłowe
- #1 Hair Loss in the UK: Facts & Statisticshttps://www.treatmentroomslondon.com/hair-loss/uk-hair-loss-facts-statistics/
Hair loss is a common concern, said to affect more than 56 million people worldwide, and the UK is no exception. […] Approximately 6.5 million men and 8 million women in the UK are currently affected by hair loss. […] The most common cause of hair loss is androgenic alopecia or male/ female pattern hair loss which affects 85% of men by the age of 50 and 40% of women by the age of 50. […] One cause behind this is alopecia areata â an immune condition known to affect 1 person out of every 500 in the UK. […] Male pattern baldness, known as androgenetic alopecia, is a highly prevalent condition that affects approximately 85% of all men by the age of 50. […] While many of the conversations around hair loss traditionally focus on men, approximately 40% of women show signs of hair loss by 50, with less than 45% of women reaching 80 with a full head of hair.
- #2 Alopecia – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK538178/
A 2019 multicenter retrospective study was performed to analyze „the frequency of the types of alopecia in patients consulting at specialist hair clinics and to assess for global variations.” […] Over 3000 diagnoses of alopecia were included, of which 73% were nonscarring, and 27% were scarring. […] The frequency of the other alopecia types listed is less than 2%. The article also provides „differences in the frequency of hair disorders” for gender, median age range by gender, and continent.
- #3 Editor’s Pick: Diagnostic Evaluation of Hair Loss: A Narrative Review – European Medical Journalhttps://www.emjreviews.com/dermatology/article/diagnostic-evaluation-of-hair-loss-a-narrative-review/
The psychosocial impact of alopecia on the quality of life of patients underscores the importance of dermatologist readiness to evaluate this common chief complaint. […] Each type of scarring or non-scarring alopecia presents with its own unique aetiology, epidemiology, clinical presentation, trichoscopic findings, and laboratory studies. […] When evaluating a patient presenting with new-onset hair loss, the differential diagnosis may be broad, encompassing many subtypes of hair loss. […] This review provides a systematic approach for dermatologists to use in order to accurately diagnose hair loss disorders, including clinical examination, laboratory evaluation, and specialised tests. […] The psychosocial impact of hair loss on the quality of life of patients underscores the importance of dermatologist readiness to evaluate this common chief complaint. […] Each type of scarring or non-scarring alopecia presents with its own unique aetiology, epidemiology, clinical presentation, trichoscopic findings, laboratory studies, and potential management tools.
- #4 Hair Loss in the UK: Facts & Statisticshttps://www.treatmentroomslondon.com/hair-loss/uk-hair-loss-facts-statistics/
Female pattern hair loss, a condition that causes hair to thin and fall out, is estimated to affect a third of women. […] Female hair loss has become a growing issue in the UK since the recent stresses associated with factors like the pandemic, cost-of-living crisis and social media, with almost 90% of requests for hair loss treatment now coming from women. […] Regardless of gender, experiencing hair loss can have a substantial psychological impact on peopleâs self-esteem, body image and overall wellbeing. […] Hair loss is a massive concern for many people across the UK due to its impact on different ages and genders, and its psychological effects on self-esteem.
- #5 Editor’s Pick: Diagnostic Evaluation of Hair Loss: A Narrative Review – European Medical Journalhttps://www.emjreviews.com/dermatology/article/diagnostic-evaluation-of-hair-loss-a-narrative-review/
The psychosocial impact of alopecia on the quality of life of patients underscores the importance of dermatologist readiness to evaluate this common chief complaint. […] Each type of scarring or non-scarring alopecia presents with its own unique aetiology, epidemiology, clinical presentation, trichoscopic findings, and laboratory studies. […] When evaluating a patient presenting with new-onset hair loss, the differential diagnosis may be broad, encompassing many subtypes of hair loss. […] This review provides a systematic approach for dermatologists to use in order to accurately diagnose hair loss disorders, including clinical examination, laboratory evaluation, and specialised tests. […] The psychosocial impact of hair loss on the quality of life of patients underscores the importance of dermatologist readiness to evaluate this common chief complaint. […] Each type of scarring or non-scarring alopecia presents with its own unique aetiology, epidemiology, clinical presentation, trichoscopic findings, laboratory studies, and potential management tools.
- #6 Androgenetic Alopecia – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK430924/
Androgenetic alopecia is a genetically predetermined disorder due to an excessive response to androgens. This condition affects up to 50 percent of males and females and is characterized by progressive loss of terminal hair of the scalp any time after puberty. It follows a characteristic distribution in both males and females. […] Pattern or androgenetic alopecia is a genetically predetermined disorder due to excessive response to androgens, impacting approximately 50% of males and females. This condition is characterized by progressive loss of terminal hair of the scalp, typically occurring following puberty, with a distinctive pattern in both males and females. […] Epidemiology: Caucasian individuals are most notably more affected, followed by Asians and African Americans, and subsequently by Native American and Inuit populations. The incidence aligns closely with age in Caucasian males, as approximately 50% are affected by 50 and approximately 80% by age 70. The disorder is quite common in females, with its incidence showing a notable rise after menopause.
- #7 Epidemiology and disease burden of androgenetic alopecia in college freshmen in China: A population-based study | PLOS Onehttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0263912
Epidemiology of AGA has been extensively studied. In general, AGA is affecting about 0.22% of all the populations in the world and the prevalence of AGA is known to differ between genders and races. […] A epidemiological surveys in China reported that the prevalence of AGA increased from 2.8% and 1.3% in men and women aged 1829 to 41.4% and 11.8% aged older than 70. […] The prevalence of AGA in college freshmen in China was 5.3/1000. Male was significantly associated with higher prevalence of AGA (7.9/1000, P0.01) while female with lower risk of AGA (OR = 0.29, P = 0.002). […] The disease burden of AGA is usually measured by several different dimensions including health-related quality of life, anxiety, depression, and quality of sleep, etc. […] Our results revealed that the HrQoL was almost unaffected among college students with AGA compared to those without AGA.
- #8 Types of Hair Loss | NYU Langone Healthhttps://nyulangone.org/conditions/hair-loss/types
Hair loss, also called alopecia, is a disorder caused by an interruption in the bodys cycle of hair production. […] Hair loss may be linked to a persons genetics, although many medical and behavioral conditions may interrupt the growth cycle and cause hair loss. […] Androgenetic alopecia is the most common type of hair loss, affecting more than 50 million men and 30 million women in the United States. […] Telogen effluvium, a type of hair loss, occurs when large numbers of follicles on the scalp enter the resting phase of the hair growth cycle, called telogen, but the next growth phase doesnt begin. […] Telogen effluvium does not generally lead to complete baldness, although you may lose 300 to 500 hairs per day, and hair may appear thin, especially at the crown and temples. […] Alopecia areata is an autoimmune condition, which means the bodys immune system attacks healthy tissues, including the hair follicles.
- #9 Androgenetic alopecia: An update – Indian Journal of Dermatology, Venereology and Leprologyhttps://ijdvl.com/androgenetic-alopecia-an-update/
Androgenetic alopecia (AGA) is considered to be the most common type of baldness characterized by progressive hair loss. AGA can affect all races, but the prevalence rates vary. Prevalence is considered to be highest in Caucasians. It is estimated that prevalence rates in Caucasian populations is around 30% for men in their 30s, 40% for men in their 40s and 50% for men in their 50s. […] In the Indian context, a population based study of 1005 subjects showed a 58% prevalence of AGA in males aged 30-50 years. […] Epidemiological studies of AGA in women are fewer in number. A study by Norwood, showed a total prevalence of around 19% in a population of 1006 Caucasian patients. […] In a Chinese population study, the prevalence was only 6.0% and a Korean study had a relatively similar lower prevalence of 5.6%, suggesting that like in men, the prevalence is considered to be lower in oriental races compared to Caucasians. […] The incidence of AGA in women also tends to increase with age. […] It should be noted that experts have suggested that female androgenetic alopecia is not exactly the female counterpart of male AGA.
- #10 Androgenetic alopecia: An update – Indian Journal of Dermatology, Venereology and Leprologyhttps://ijdvl.com/androgenetic-alopecia-an-update/
Androgenetic alopecia (AGA) is considered to be the most common type of baldness characterized by progressive hair loss. AGA can affect all races, but the prevalence rates vary. Prevalence is considered to be highest in Caucasians. It is estimated that prevalence rates in Caucasian populations is around 30% for men in their 30s, 40% for men in their 40s and 50% for men in their 50s. […] In the Indian context, a population based study of 1005 subjects showed a 58% prevalence of AGA in males aged 30-50 years. […] Epidemiological studies of AGA in women are fewer in number. A study by Norwood, showed a total prevalence of around 19% in a population of 1006 Caucasian patients. […] In a Chinese population study, the prevalence was only 6.0% and a Korean study had a relatively similar lower prevalence of 5.6%, suggesting that like in men, the prevalence is considered to be lower in oriental races compared to Caucasians. […] The incidence of AGA in women also tends to increase with age. […] It should be noted that experts have suggested that female androgenetic alopecia is not exactly the female counterpart of male AGA.
- #11 Androgenetic Alopecia – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK430924/
Androgenetic alopecia is a genetically predetermined disorder due to an excessive response to androgens. This condition affects up to 50 percent of males and females and is characterized by progressive loss of terminal hair of the scalp any time after puberty. It follows a characteristic distribution in both males and females. […] Pattern or androgenetic alopecia is a genetically predetermined disorder due to excessive response to androgens, impacting approximately 50% of males and females. This condition is characterized by progressive loss of terminal hair of the scalp, typically occurring following puberty, with a distinctive pattern in both males and females. […] Epidemiology: Caucasian individuals are most notably more affected, followed by Asians and African Americans, and subsequently by Native American and Inuit populations. The incidence aligns closely with age in Caucasian males, as approximately 50% are affected by 50 and approximately 80% by age 70. The disorder is quite common in females, with its incidence showing a notable rise after menopause.
- #12 Alopecia epidemiology and demographics – wikidochttps://www.wikidoc.org/index.php/Alopecia_epidemiology_and_demographics
The overall incidence of alopecia areata is approximately 20.2 per 100,000 person-years. […] About 50,000 per 100,000 Caucasian males have androgenetic alopecia by the time they are 50 years old. This number rises to about 80,000 per 100,000 by the age of 70 years. […] The risk of androgenetic alopecia increases with age. Up to 80,000 per 100,000 Caucasian men over the age of 70 years have androgenetic alopecia compared to 50,000 per 100,000 in Caucasian men who are 50 years. […] In telogen effluvium, women are at higher predisposition than men. […] Alopecia areata can occur in adults and children and distribution is about equal between the sexes. […] Traction alopecia is seen most commonly in females, the majority of whom are of African-American descent. […] Traction alopecia is seen most commonly in African-American females. This is likely as a result of certain hairstyles that are more predominantly made by African-Americans. […] Caucasian males have the highest incidence of androgenetic alopecia. They are followed by Asian males, African-American males, and lastly, Native Americans and Eskimos.
- #13 Pattern hair loss – Wikipediahttps://en.wikipedia.org/wiki/Pattern_hair_loss
Female androgenic alopecia has become a growing problem that, according to the American Academy of Dermatology, affects around 30 million women in the United States. […] For male androgenic alopecia, by the age of 50 30-50% of men have it, hereditarily there is an 80% predisposition.
- #14 Androgenetic alopecia: An update – Indian Journal of Dermatology, Venereology and Leprologyhttps://ijdvl.com/androgenetic-alopecia-an-update/
Androgenetic alopecia (AGA) is considered to be the most common type of baldness characterized by progressive hair loss. AGA can affect all races, but the prevalence rates vary. Prevalence is considered to be highest in Caucasians. It is estimated that prevalence rates in Caucasian populations is around 30% for men in their 30s, 40% for men in their 40s and 50% for men in their 50s. […] In the Indian context, a population based study of 1005 subjects showed a 58% prevalence of AGA in males aged 30-50 years. […] Epidemiological studies of AGA in women are fewer in number. A study by Norwood, showed a total prevalence of around 19% in a population of 1006 Caucasian patients. […] In a Chinese population study, the prevalence was only 6.0% and a Korean study had a relatively similar lower prevalence of 5.6%, suggesting that like in men, the prevalence is considered to be lower in oriental races compared to Caucasians. […] The incidence of AGA in women also tends to increase with age. […] It should be noted that experts have suggested that female androgenetic alopecia is not exactly the female counterpart of male AGA.
- #15 Androgenetic alopecia: An update – Indian Journal of Dermatology, Venereology and Leprologyhttps://ijdvl.com/androgenetic-alopecia-an-update/
Androgenetic alopecia (AGA) is considered to be the most common type of baldness characterized by progressive hair loss. AGA can affect all races, but the prevalence rates vary. Prevalence is considered to be highest in Caucasians. It is estimated that prevalence rates in Caucasian populations is around 30% for men in their 30s, 40% for men in their 40s and 50% for men in their 50s. […] In the Indian context, a population based study of 1005 subjects showed a 58% prevalence of AGA in males aged 30-50 years. […] Epidemiological studies of AGA in women are fewer in number. A study by Norwood, showed a total prevalence of around 19% in a population of 1006 Caucasian patients. […] In a Chinese population study, the prevalence was only 6.0% and a Korean study had a relatively similar lower prevalence of 5.6%, suggesting that like in men, the prevalence is considered to be lower in oriental races compared to Caucasians. […] The incidence of AGA in women also tends to increase with age. […] It should be noted that experts have suggested that female androgenetic alopecia is not exactly the female counterpart of male AGA.
- #16 Baldness: How close are we to a cure?https://www.medicalnewstoday.com/articles/317788
Androgenetic alopecia which is more commonly known as male pattern baldness and female pattern baldness is the most common type of hair loss, affecting around 30 million women and 50 million men across the United States. […] Male pattern baldness is hereditary and may be linked to male sex hormones. Male hair loss can start as early as during adolescence. It affects two thirds of men by age 35, and around 85 percent of men by the age of 50. […] The causes of female pattern baldness are unclear. However, hair loss happens most frequently in women after menopause, which indicates that the condition may be associated with decreasing female hormones. […] Currently, there are few available treatment options to halt or reverse miniaturization. Most hair loss treatments only manage hair loss, rather than being a permanent solution.
- #17 Androgenetic Alopecia: Practice Essentials, Background, Pathophysiologyhttps://emedicine.medscape.com/article/1070167-overview
Androgenetic alopecia is an extremely common disorder that affects roughly 50% of men and perhaps as many women older than 40 years. […] As many as 13% of premenopausal women reportedly have some evidence of androgenetic alopecia. However, the incidence of androgenetic alopecia increases greatly in women following menopause, and, according to one author, it may affect 75% of women older than 65 years. […] The incidence and the severity of androgenetic alopecia tend to be highest in white men, second highest in Asians and African Americans, and lowest in Native Americans and Eskimos. […] Almost all patients with androgenetic alopecia have an onset prior to age 40 years, although many of the patients (both male and female) show evidence of the disorder by age 30 years.
- #18 Female pattern hair loss – Indian Journal of Dermatology, Venereology and Leprologyhttps://ijdvl.com/female-pattern-hair-loss/
In UK, 6% women aged less than 50 years were diagnosed as having FPHL, increasing to 38% in subjects aged 70 years and above. […] Overall, the prevalence of mid-frontal hair loss increased with age and affected 57% of women aged 80 years and above. […] In another study comprising 1006 Caucasian women, the FPHL was found to be common beginning in the late 20s and reaching its peak after 50 years of age.
- #19 Female pattern hair losshttps://www1.racgp.org.au/ajgp/2018/july/female-pattern-hair-loss
Approximately 49% of women will be affected by hair loss throughout their lives, with female pattern hair loss (FPHL) being the most common cause of female alopecia. The incidence steadily increases with age in all ethnicities, and the age-adjusted prevalence among adult Australian women of European descent is 32%. This translates to 800,000 women who suffer from moderate-to-severe FPHL. […] One study found that patterned hair loss was an independent predictor of mortality from diabetes mellitus and heart disease in both females and males. Screening for metabolic cardiovascular risk factors is useful in patients presenting with patterned hair loss. […] The risk factors for FPHL include increasing age, family history, smoking, elevated fasting glucose levels and ultraviolet light exposure of 16 hours/week.
- #20 Alopecia areata: Clinical manifestations and diagnosis – UpToDatehttps://www.uptodate.com/contents/alopecia-areata-clinical-manifestations-and-diagnosis
Alopecia areata occurs worldwide, but the incidence and prevalence vary geographically and across subpopulations. Epidemiologic studies from the United States and the United Kingdom have estimated the overall incidence between 0.21 and 0.26 per 1000 patient-years (approximately 1 new case per 4000 population per year) and the point prevalence at 0.16 to 0.21 percent (approximately 1 in 500 have active alopecia areata). The cumulative lifetime incidence (the lifetime risk) is around 2 percent (ie, 1 in 50 will develop alopecia areata at some time in their lives).
- #21 Alopecia areata: Clinical manifestations and diagnosis – UpToDatehttps://www.uptodate.com/contents/alopecia-areata-clinical-manifestations-and-diagnosis
Alopecia areata occurs worldwide, but the incidence and prevalence vary geographically and across subpopulations. Epidemiologic studies from the United States and the United Kingdom have estimated the overall incidence between 0.21 and 0.26 per 1000 patient-years (approximately 1 new case per 4000 population per year) and the point prevalence at 0.16 to 0.21 percent (approximately 1 in 500 have active alopecia areata). The cumulative lifetime incidence (the lifetime risk) is around 2 percent (ie, 1 in 50 will develop alopecia areata at some time in their lives).
- #22 Alopecia areata: Clinical manifestations and diagnosis – UpToDatehttps://www.uptodate.com/contents/alopecia-areata-clinical-manifestations-and-diagnosis
Alopecia areata occurs worldwide, but the incidence and prevalence vary geographically and across subpopulations. Epidemiologic studies from the United States and the United Kingdom have estimated the overall incidence between 0.21 and 0.26 per 1000 patient-years (approximately 1 new case per 4000 population per year) and the point prevalence at 0.16 to 0.21 percent (approximately 1 in 500 have active alopecia areata). The cumulative lifetime incidence (the lifetime risk) is around 2 percent (ie, 1 in 50 will develop alopecia areata at some time in their lives).
- #23 Epidemiology and burden of alopecia areata: a systematic review | CCIDhttps://www.dovepress.com/epidemiology-and-burden-of-alopecia-areata-a-systematic-review-peer-reviewed-fulltext-article-CCID
Alopecia areata (AA) is an autoimmune disorder characterized by patches of non-scarring alopecia affecting scalp and body hair that can be psychologically devastating. […] The objective of this study is to provide an evidence-based systematic review on the epidemiology and the burden of AA. […] The lifetime incidence of AA is approximately 2% worldwide. […] AA is the most prevalent autoimmune disorder and the second most prevalent hair loss disorder after androgenetic alopecia, and the lifetime risk in the global population is approximately 2%. […] The estimated incidence of AA was approximately 2% in the population studies and close to 2% in hospital-based studies globally. […] There appears to be no significant difference in the incidence of AA between males and females as both formal population studies found none, and hospital-based studies are mixed in citing a female vs male predominance.
- #24https://link.springer.com/article/10.1007/s13555-024-01145-9
This cohort study reported incidence rates and prevalence over time and characteristics of individuals with hospital-treated AA in Denmark, which are in agreement with those previously reported in this population. […] In this population-based cohort study in Denmark, we observed the overall incidence rate for any hospital-treated AA per 100,000 person-years of 2.62 (95% CI 2.53-2.72) and the overall prevalence in 2016 of 71.7 (95% CI 69.4-74.1) per 100,000 persons. The prevalence of both AT/AU and non-AT/AU subtypes increased over time. […] The reported incidence rate for all AA types in 2016 of 4.0 per 100,000 is lower than that in previous reports. […] The approximately 10-fold lower prevalence and incidence for all AA types reported in Denmark compared with UK-, USA-, and South Korean-based estimates are likely explained by the potentially large number of patients with AA diagnosed and treated in general practice and therefore not included in this study.
- #25 Sign up for our newsletterhttps://www.alopecia.org.uk/blog/epic-epidemiology-study-for-alopecia-areata
At the end of 2018, 1 in 170 people in the study population either had active alopecia areata now or had had it in the past. This figure is known as the prevalence of the disease. […] Alopecia areata was slightly more common in women than in men. […] Alopecia areata can start at any age but the peak age of onset is between 25-29. […] Alopecia areata is more common in people living in urban areas compared to rural areas. […] Alopecia areata is more common in people living in socially deprived areas. […] Alopecia areata is more common in people of non-white ethnicity compared to those of white ethnicity. It was three times as common in people of Asian ethnicity. […] 1 in 4 people with AA are referred to a dermatologist. The proportion increased steadily over the 10 years of the study.
- #26 Sign up for our newsletterhttps://www.alopecia.org.uk/blog/epic-epidemiology-study-for-alopecia-areata
At the end of 2018, 1 in 170 people in the study population either had active alopecia areata now or had had it in the past. This figure is known as the prevalence of the disease. […] Alopecia areata was slightly more common in women than in men. […] Alopecia areata can start at any age but the peak age of onset is between 25-29. […] Alopecia areata is more common in people living in urban areas compared to rural areas. […] Alopecia areata is more common in people living in socially deprived areas. […] Alopecia areata is more common in people of non-white ethnicity compared to those of white ethnicity. It was three times as common in people of Asian ethnicity. […] 1 in 4 people with AA are referred to a dermatologist. The proportion increased steadily over the 10 years of the study.
- #27 Types of Hair Loss | NYU Langone Healthhttps://nyulangone.org/conditions/hair-loss/types
Tinea capitis, also called scalp ringworm, is a fungal infection of the scalp thats a common cause of hair loss in children. […] Cicatricial alopecia, also known as scarring alopecia, is a rare type of hair loss in which inflammation destroys hair follicles and causes scar tissue to form in their place. […] Hair loss caused by folliculitis decalvans, an inflammatory disorder that leads to the destruction of hair follicles, is often accompanied by redness, swelling, and lesions on the scalp that may be itchy or contain pus, known as pustules. […] Frontal fibrosing alopecia typically occurs in a receding hairline pattern and may also result in hair loss in the eyebrows and underarms. […] Central centrifugal cicatricial alopecia may occur as a result of hair products or styling techniques that damage hair follicles.
- #28 Scarring Alopecia: Practice Essentials, Pathophysiology, Epidemiologyhttps://emedicine.medscape.com/article/1073559-overview
Epidemiology studies are mostly from clinics dedicated to alopecia. Within the alopecia population, the prevalence of scarring alopecia is believed to be approximately 7%. […] No large evidence-based medicine studies are available to report the epidemiology of lichen planopilaris, central centrifugal cicatricial alopecia, or pseudopelade in the general population. […] Traction alopecia is most commonly seen in the African American population because of the practice of styling the hair in tight braids or the use of chemical hair straighteners. […] Traction alopecia is also reported in nurses who secure their nurse’s caps to their scalp with bobby pins. […] The exact frequency of traction alopecia in the United States has yet to be documented. […] Traction alopecia is seen worldwide. Its frequency usually depends on cultural customs.
- #29 Scarring Alopecia: Practice Essentials, Pathophysiology, Epidemiologyhttps://emedicine.medscape.com/article/1073559-overview
Epidemiology studies are mostly from clinics dedicated to alopecia. Within the alopecia population, the prevalence of scarring alopecia is believed to be approximately 7%. […] No large evidence-based medicine studies are available to report the epidemiology of lichen planopilaris, central centrifugal cicatricial alopecia, or pseudopelade in the general population. […] Traction alopecia is most commonly seen in the African American population because of the practice of styling the hair in tight braids or the use of chemical hair straighteners. […] Traction alopecia is also reported in nurses who secure their nurse’s caps to their scalp with bobby pins. […] The exact frequency of traction alopecia in the United States has yet to be documented. […] Traction alopecia is seen worldwide. Its frequency usually depends on cultural customs.
- #30 Scarring Alopecia: Practice Essentials, Pathophysiology, Epidemiologyhttps://emedicine.medscape.com/article/1073559-overview
Population studies show a prevalence of 17.1% in African schoolgirls (6-21 y) and of 31.7% in women (18-86 y). […] Scarring alopecia prevalence studies are otherwise still lacking. Partial hindrance of such data production is based on the lack of well-established diagnostic criteria. […] Central centrifugal cicatricial alopecia is believed to be predominant in African Americans, while lichen planopilaris occurs mostly in lighter-skinned patients. […] The sex distribution of scarring alopecia is anecdotally believed to be predominantly favoring the female population. […] Traction alopecia is initially seen in children and young adults. […] However, in the African American population, this entity is a significant cause of alopecia. […] The exact frequency has yet to be documented in children, young adults, and adults. […] Age distribution on the other scarring alopecia types has not been well studied. The majority of case reports suggest these conditions present in persons older than 20 years.
- #31https://journals.lww.com/ijd/fulltext/2022/67050/clinico_epidemiology_and_histopathologic_spectrum.40.aspx
PSA includes a rare, diverse group of disorders characterized by irreversible destruction of hair follicles resulting in scarring and permanent hair loss. […] PSA are a diagnostic challenge due to overlapping clinical and histopathological features, more so in cases of delayed presentation due to non-specific histology. […] We diagnosed PSA in 61 patients during the study period among 66,370 patients attending our dermatology OPD, thus accounting for a prevalence of 0.09% (61/66,370). […] Fifty-three patients presented with PSA, diagnosed by clinico-pathological correlation. The most common subtype of PSA was LPP (39.6%, 21/53) […] The mean age of our patients was 30.9 8.1 years (range 150 years), more than half (52.8%, 28/53) belonging to 3039 year age group. Overall, female predominance was noted (M: F 24:29)
- #32 Alopecia Areata: Causes & Treatment | Doctorhttps://patient.info/doctor/alopecia
Alopecia describes loss of hair from areas where hair normally grows. […] Aetiology, epidemiology and management will vary between them. […] Increasingly common with age. […] Half of men are affected by the age of 50. […] Significant ethnic variations – white men are affected four times more than those of Afro-Caribbean origin. Alopecia tends to occur later and more slowly in Asian men. […] Reported prevalence rates vary widely. […] It increases after the menopause. […] It affects around one third of white Caucasian women over the age of 70. […] There is ethnic variation with it being less common in women of Oriental origin. […] Estimated prevalence in the UK is 15 per 10,000 of the population. […] It can affect any age but onset is most common in childhood and adolescence. Incidence peaks between the ages of 15 and 29. […] Males and females are affected equally. […] Severity at presentation is the best indicator of long-term outcome.
- #33 Alopecia Areata: Causes & Treatment | Doctorhttps://patient.info/doctor/alopecia
Alopecia describes loss of hair from areas where hair normally grows. […] Aetiology, epidemiology and management will vary between them. […] Increasingly common with age. […] Half of men are affected by the age of 50. […] Significant ethnic variations – white men are affected four times more than those of Afro-Caribbean origin. Alopecia tends to occur later and more slowly in Asian men. […] Reported prevalence rates vary widely. […] It increases after the menopause. […] It affects around one third of white Caucasian women over the age of 70. […] There is ethnic variation with it being less common in women of Oriental origin. […] Estimated prevalence in the UK is 15 per 10,000 of the population. […] It can affect any age but onset is most common in childhood and adolescence. Incidence peaks between the ages of 15 and 29. […] Males and females are affected equally. […] Severity at presentation is the best indicator of long-term outcome.
- #34 Alopecia areata – Wikipediahttps://en.wikipedia.org/wiki/Alopecia_areata
The condition affects 0.1%0.2% of the population, with a lifetime risk of 1%-2%, and is more common in females. […] Alopecia areata occurs in people who are otherwise healthy and have no other skin disorders. Initial presentation most commonly occurs in the early childhood, late teenage years, or young adulthood, but can happen at any ages. Patients also tend to have a slightly higher incidence of conditions related to the immune system, such as asthma, allergies, atopic dermatitis, and hypothyroidism. […] The prevalence and impact of AA vary across different ethnic groups and socioeconomic backgrounds. Studies indicate that people of Asian descent have the highest risk, with nearly 6 cases per 100 people, compared to fewer than 2 cases per 100 people among White individuals. People living in urban or economically disadvantaged areas face a higher likelihood of developing AA. The effects of the condition also differ by ethnicity: individuals of Black descent with AA are more likely to experience anxiety and require medical leave from work. These findings suggest that genetic, environmental, and social factors may influence both the likelihood of developing AA and its broader personal and professional impact.
- #35 Scarring Alopecia: Practice Essentials, Pathophysiology, Epidemiologyhttps://emedicine.medscape.com/article/1073559-overview
Population studies show a prevalence of 17.1% in African schoolgirls (6-21 y) and of 31.7% in women (18-86 y). […] Scarring alopecia prevalence studies are otherwise still lacking. Partial hindrance of such data production is based on the lack of well-established diagnostic criteria. […] Central centrifugal cicatricial alopecia is believed to be predominant in African Americans, while lichen planopilaris occurs mostly in lighter-skinned patients. […] The sex distribution of scarring alopecia is anecdotally believed to be predominantly favoring the female population. […] Traction alopecia is initially seen in children and young adults. […] However, in the African American population, this entity is a significant cause of alopecia. […] The exact frequency has yet to be documented in children, young adults, and adults. […] Age distribution on the other scarring alopecia types has not been well studied. The majority of case reports suggest these conditions present in persons older than 20 years.
- #36 Scarring Alopecia: Practice Essentials, Pathophysiology, Epidemiologyhttps://emedicine.medscape.com/article/1073559-overview
Epidemiology studies are mostly from clinics dedicated to alopecia. Within the alopecia population, the prevalence of scarring alopecia is believed to be approximately 7%. […] No large evidence-based medicine studies are available to report the epidemiology of lichen planopilaris, central centrifugal cicatricial alopecia, or pseudopelade in the general population. […] Traction alopecia is most commonly seen in the African American population because of the practice of styling the hair in tight braids or the use of chemical hair straighteners. […] Traction alopecia is also reported in nurses who secure their nurse’s caps to their scalp with bobby pins. […] The exact frequency of traction alopecia in the United States has yet to be documented. […] Traction alopecia is seen worldwide. Its frequency usually depends on cultural customs.
- #37 Survey: Almost half of African-American women have experienced hair loss | ScienceDailyhttps://www.sciencedaily.com/releases/2016/03/160304093239.htm
African-American women are prone to hair loss, and new data illustrates the scope of this problem, which often goes undiagnosed. […] Dr. Lenzy partnered with the Black Women’s Health Study at Boston University’s Slone Epidemiology Center to survey African-American women about their experiences with hair loss. Of the 5,594 women who have completed the survey so far, 47.6 percent reported hair loss on the crown or top of the scalp. […] Although hair loss is common among American-American women, Dr. Lenzy says, this problem often goes undiagnosed because patients don’t know they should visit a dermatologist for evaluation; the vast majority of survey respondents (81.4 percent) indicated that they had never seen a physician about hair loss.
- #38 Advancing Research on Alopecia Areata Treatment and Epidemiologyhttps://www.ajmc.com/view/advancing-research-on-alopecia-areata-treatment-and-epidemiology
Mostaghimi focuses on the progress made in understanding the epidemiology of alopecia areata and the development of new treatments but acknowledges the current obstacles that remain. […] We have a much greater understanding of the epidemiology of alopecia areata than we did years ago. Despite this, our epidemiology is at the level where we understand patterns at a population level, but we haven’t quite figured out variation between specific patients with regards to disease severity, response to therapy, and risk of relapse. […] Other open questions include whether or not earlier and more aggressive treatment of alopecia areata can prevent the development of comorbidities both psychiatric and otherwise. This is a real-world question that may inform patients on the fence about treatment.
- #39 Epidemiology and burden of alopecia areata: a systematic review | CCIDhttps://www.dovepress.com/epidemiology-and-burden-of-alopecia-areata-a-systematic-review-peer-reviewed-fulltext-article-CCID
Most patients experience their first onset of AA by age 40 years, with a peak of incidences occurring in their 20s and 30s. […] The scalp is involved with or without involvement of other body sites in almost all cases of AA, with the occipital scalp being the most commonly involved site. […] The Global Burden of Disease Study, which estimates the DALYs for AA to be 1,332,800, or a weighted 0.035, may underestimate the true population-based prevalence and disease burden due to patients with AA who do not present for care. […] AA leads to decreased QOL in half of its sufferers and is associated with an approximately 70% lifetime prevalence of psychiatric disorders, most commonly depression, anxiety, and adjustment disorders. […] AA appears to be associated with atopy and many autoimmune diseases including vitiligo and thyroid disorders.
- #40 Androgenetic Alopecia – Epidemiology Forecast – 2032https://www.researchandmarkets.com/reports/5525139/androgenetic-alopecia-epidemiology-forecast?srsltid=AfmBOorDvlLD93Y6N1cdPb0J4QZabNfuI6ZImQ6IA1MVgDt3A2LnrThN
This Androgenetic Alopecia – Epidemiology Forecast – 2032′ report delivers an in-depth understanding of the historical and forecasted epidemiology of androgenetic alopecia in the United States, EU4 (Germany, Spain, Italy, France) and the United Kingdom and Japan. […] The androgenetic alopecia epidemiology division provides insights into the historical and current patient pool and the forecast trend for every seven major countries. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the report also provides the diagnosed patient pool and their trends, along with assumptions undertaken. […] The disease epidemiology covered in the report provides historical and forecasted androgenetic alopecia epidemiology segmented as the total prevalent cases of androgenetic alopecia, total prevalent cases of androgenetic alopecia in males, total prevalent cases of androgenetic alopecia in females, total diagnosed prevalent cases of androgenetic alopecia in males and total diagnosed prevalent cases of androgenetic alopecia in females. The report includes the total prevalent cases of androgenetic alopecia in the 7MM covering the United States, EU4 (Germany, Spain, Italy, France) and the UK, and Japan from 2019 to 2032.
- #41 Androgenetic Alopecia – Epidemiology Forecast – 2032https://www.researchandmarkets.com/reports/5525139/androgenetic-alopecia-epidemiology-forecast?srsltid=AfmBOorDvlLD93Y6N1cdPb0J4QZabNfuI6ZImQ6IA1MVgDt3A2LnrThN
The epidemiology segment also provides the androgenetic alopecia epidemiology data and findings across the United States, EU4 (Germany, Spain, Italy, France) and the UK, and Japan. The total prevalent cases of androgenetic alopecia were more than 194,000,000 in the 7MM in 2021. […] As per the estimates, EU4 and the UK had the highest prevalent patient population of androgenetic alopecia in 2021. Among EU4 and the UK, Germany had the highest number of cases of androgenetic alopecia, with more than 22,000,000 cases, followed by the UK in 2021. On the other hand, Spain had the lowest number of cases of androgenetic alopecia, with nearly 12,000,000 cases in 2021. […] The report helps recognize the growth opportunities in the 7MM concerning the patient population. […] The report assesses the disease risk and burden and highlights the unmet needs of androgenetic alopecia. […] The report describes Androgenetic Alopecia epidemiology by the number of patients developing androgenetic alopecia in the 7MM. […] The report describes the androgenetic alopecia epidemiology by the type-specific cases of androgenetic alopecia patients in the 7MM.
- #42 Alopecia Areata – Epidemiology Forecast to 2028https://www.globaldata.com/store/report/alopecia-areata-epidemiology-forecast-to-2028/
The following data describes epidemiology of AA. GlobalData epidemiologists forecast an increase in the diagnosed incident cases of AA in the 7MM from 156,056 diagnosed incident cases in 2018 to 157,883 diagnosed incident cases in 2028, with an Annual Growth Rate (AGR) of 0.12% during the forecast period. The US will have the highest number of diagnosed incident cases of AA among the 7MM, while Spain will have the lowest. GlobalData epidemiologists forecast an increase in the lifetime diagnosed prevalent cases of AA in the 7MM from 6,388,360 lifetime diagnosed prevalent cases in 2018 to 6,473,746 lifetime diagnosed prevalent cases in 2028, with an AGR of 0.13% during the forecast period. US will have the highest number of lifetime diagnosed prevalent cases of AA among the 7MM, while Spain will have the lowest.
- #43 Scarring Alopecia: Practice Essentials, Pathophysiology, Epidemiologyhttps://emedicine.medscape.com/article/1073559-overview
Population studies show a prevalence of 17.1% in African schoolgirls (6-21 y) and of 31.7% in women (18-86 y). […] Scarring alopecia prevalence studies are otherwise still lacking. Partial hindrance of such data production is based on the lack of well-established diagnostic criteria. […] Central centrifugal cicatricial alopecia is believed to be predominant in African Americans, while lichen planopilaris occurs mostly in lighter-skinned patients. […] The sex distribution of scarring alopecia is anecdotally believed to be predominantly favoring the female population. […] Traction alopecia is initially seen in children and young adults. […] However, in the African American population, this entity is a significant cause of alopecia. […] The exact frequency has yet to be documented in children, young adults, and adults. […] Age distribution on the other scarring alopecia types has not been well studied. The majority of case reports suggest these conditions present in persons older than 20 years.
- #44https://link.springer.com/article/10.1007/s13555-024-01145-9
This cohort study reported incidence rates and prevalence over time and characteristics of individuals with hospital-treated AA in Denmark, which are in agreement with those previously reported in this population. […] In this population-based cohort study in Denmark, we observed the overall incidence rate for any hospital-treated AA per 100,000 person-years of 2.62 (95% CI 2.53-2.72) and the overall prevalence in 2016 of 71.7 (95% CI 69.4-74.1) per 100,000 persons. The prevalence of both AT/AU and non-AT/AU subtypes increased over time. […] The reported incidence rate for all AA types in 2016 of 4.0 per 100,000 is lower than that in previous reports. […] The approximately 10-fold lower prevalence and incidence for all AA types reported in Denmark compared with UK-, USA-, and South Korean-based estimates are likely explained by the potentially large number of patients with AA diagnosed and treated in general practice and therefore not included in this study.
- #45 GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk | Nature Communicationshttps://www.nature.com/articles/s41467-017-01490-8
In this study, we have identified and replicated numerous new loci predisposing to MPB which, together with the previously identified ones, can explain a large proportion of the estimated heritability. […] We have observed an h2SNP of 94%, which suggests that MBP is more a polygenic trait than a complex one, with very little environmental component. […] In conclusion, we show baldness to be one of the most heritable complex traits, for which we are able to explain nearly two fifths of the heritability with only 71 loci. Recurring themes in complex trait genetics are highlighted, including multiple distinct signals in many loci, aggregation of genetic effects in pathways important to the trait and widespread pleiotropy with other traits and diseases; but we also emphasise pathway-specific genetic correlations as a new approach to dissect the genetics and biology of complex diseases.
- #46 Advancing Research on Alopecia Areata Treatment and Epidemiologyhttps://www.ajmc.com/view/advancing-research-on-alopecia-areata-treatment-and-epidemiology
Mostaghimi focuses on the progress made in understanding the epidemiology of alopecia areata and the development of new treatments but acknowledges the current obstacles that remain. […] We have a much greater understanding of the epidemiology of alopecia areata than we did years ago. Despite this, our epidemiology is at the level where we understand patterns at a population level, but we haven’t quite figured out variation between specific patients with regards to disease severity, response to therapy, and risk of relapse. […] Other open questions include whether or not earlier and more aggressive treatment of alopecia areata can prevent the development of comorbidities both psychiatric and otherwise. This is a real-world question that may inform patients on the fence about treatment.
- #47https://journals.lww.com/ijot/fulltext/2018/10020/alopecia_areata__review_of_epidemiology,_clinical.1.aspx
AA is an autoimmune condition that attacks the hair follicles, causing nonscarring hair loss. Population studies from the Rochester Epidemiology Project estimate a lifetime incidence of AA of 2.1%, in a population in Olmsted County, Minnesota, with no difference in incidence between genders. […] A systemic review of the epidemiology of AA indicated a similar worldwide lifetime incidence of around 2%. […] The disorder can occur at any age and the lifetime incidence appears to increase at an almost linear rate. […] The median age at diagnosis is 33. […] Male patients may be more likely to be diagnosed in childhood, while females are more likely to present in adolescence and have greater concomitant nail involvement or concomitant autoimmune diseases.
- #48 Epidemiology and burden of alopecia areata: a systematic review | CCIDhttps://www.dovepress.com/epidemiology-and-burden-of-alopecia-areata-a-systematic-review-peer-reviewed-fulltext-article-CCID
Most patients experience their first onset of AA by age 40 years, with a peak of incidences occurring in their 20s and 30s. […] The scalp is involved with or without involvement of other body sites in almost all cases of AA, with the occipital scalp being the most commonly involved site. […] The Global Burden of Disease Study, which estimates the DALYs for AA to be 1,332,800, or a weighted 0.035, may underestimate the true population-based prevalence and disease burden due to patients with AA who do not present for care. […] AA leads to decreased QOL in half of its sufferers and is associated with an approximately 70% lifetime prevalence of psychiatric disorders, most commonly depression, anxiety, and adjustment disorders. […] AA appears to be associated with atopy and many autoimmune diseases including vitiligo and thyroid disorders.
- #49 Female pattern hair losshttps://www1.racgp.org.au/ajgp/2018/july/female-pattern-hair-loss
Approximately 49% of women will be affected by hair loss throughout their lives, with female pattern hair loss (FPHL) being the most common cause of female alopecia. The incidence steadily increases with age in all ethnicities, and the age-adjusted prevalence among adult Australian women of European descent is 32%. This translates to 800,000 women who suffer from moderate-to-severe FPHL. […] One study found that patterned hair loss was an independent predictor of mortality from diabetes mellitus and heart disease in both females and males. Screening for metabolic cardiovascular risk factors is useful in patients presenting with patterned hair loss. […] The risk factors for FPHL include increasing age, family history, smoking, elevated fasting glucose levels and ultraviolet light exposure of 16 hours/week.
- #50 Alopecia Areata (Baldness and Hair Loss): Causes, Symptoms and Treatmenthttps://patient.info/skin-conditions/alopecia-areata
In the UK, alopecia areata is estimated to affect about 15 in 10,000 people. […] Alopecia areata can occur at any age but about half of all cases occur in childhood and eight in ten cases start before the age of 40 years. […] People with alopecia areata have a slightly higher-than-average chance of developing other autoimmune diseases such as thyroid disease, pernicious anaemia and vitiligo. […] If less than half of the scalp is affected and no treatment is started, there is about an 80% chance of full hair regrowth within one year. […] However, even if the hair grows back fully after an episode of alopecia areata, it is common to have one or more recurrences of the condition throughout life. […] Progression to these more extensive types of hair loss is more common if the bald patches start in childhood.
- #51 Alopecia areata | Description, Types, Risk Factors, Symptoms, & Treatment | Britannicahttps://www.britannica.com/science/alopecia-areata
Alopecia areata is an autoimmune disease characterized by hair loss on the face, scalp, and sometimes other parts of the body. […] Globally, alopecia areata affects about 2 percent of individuals at some point in their lives. […] Persons who are Asian, Black, or Hispanic are more likely than white people to develop alopecia areata. […] While the precise cause of alopecia areata is unclear, the condition is associated with multiple genetic variants. […] About 20 percent of persons who develop alopecia areata have an affected relative; risk is increased particularly if the relative is an immediate family member and if that individual was affected before age 30. […] Persons who have Down syndrome or polyglandular autoimmune syndrome type 1 are also more likely to develop the disease, as are those affected by other autoimmune conditions, such as celiac disease, certain diseases of the thyroid gland, lupus erythematosus, psoriasis, rheumatoid arthritis, type 1 diabetes mellitus, and vitiligo. […] Alopecia areata is associated with an increased risk of retinal disease, including retinal detachment, retinal vascular occlusion, and retinopathy.
- #52 Alopecia areata | Description, Types, Risk Factors, Symptoms, & Treatment | Britannicahttps://www.britannica.com/science/alopecia-areata
Alopecia areata is an autoimmune disease characterized by hair loss on the face, scalp, and sometimes other parts of the body. […] Globally, alopecia areata affects about 2 percent of individuals at some point in their lives. […] Persons who are Asian, Black, or Hispanic are more likely than white people to develop alopecia areata. […] While the precise cause of alopecia areata is unclear, the condition is associated with multiple genetic variants. […] About 20 percent of persons who develop alopecia areata have an affected relative; risk is increased particularly if the relative is an immediate family member and if that individual was affected before age 30. […] Persons who have Down syndrome or polyglandular autoimmune syndrome type 1 are also more likely to develop the disease, as are those affected by other autoimmune conditions, such as celiac disease, certain diseases of the thyroid gland, lupus erythematosus, psoriasis, rheumatoid arthritis, type 1 diabetes mellitus, and vitiligo. […] Alopecia areata is associated with an increased risk of retinal disease, including retinal detachment, retinal vascular occlusion, and retinopathy.
- #53 Alopecia areata | Description, Types, Risk Factors, Symptoms, & Treatment | Britannicahttps://www.britannica.com/science/alopecia-areata
Alopecia areata is an autoimmune disease characterized by hair loss on the face, scalp, and sometimes other parts of the body. […] Globally, alopecia areata affects about 2 percent of individuals at some point in their lives. […] Persons who are Asian, Black, or Hispanic are more likely than white people to develop alopecia areata. […] While the precise cause of alopecia areata is unclear, the condition is associated with multiple genetic variants. […] About 20 percent of persons who develop alopecia areata have an affected relative; risk is increased particularly if the relative is an immediate family member and if that individual was affected before age 30. […] Persons who have Down syndrome or polyglandular autoimmune syndrome type 1 are also more likely to develop the disease, as are those affected by other autoimmune conditions, such as celiac disease, certain diseases of the thyroid gland, lupus erythematosus, psoriasis, rheumatoid arthritis, type 1 diabetes mellitus, and vitiligo. […] Alopecia areata is associated with an increased risk of retinal disease, including retinal detachment, retinal vascular occlusion, and retinopathy.
- #54 Epidemiology and burden of alopecia areata: a systematic review | CCIDhttps://www.dovepress.com/epidemiology-and-burden-of-alopecia-areata-a-systematic-review-peer-reviewed-fulltext-article-CCID
Most patients experience their first onset of AA by age 40 years, with a peak of incidences occurring in their 20s and 30s. […] The scalp is involved with or without involvement of other body sites in almost all cases of AA, with the occipital scalp being the most commonly involved site. […] The Global Burden of Disease Study, which estimates the DALYs for AA to be 1,332,800, or a weighted 0.035, may underestimate the true population-based prevalence and disease burden due to patients with AA who do not present for care. […] AA leads to decreased QOL in half of its sufferers and is associated with an approximately 70% lifetime prevalence of psychiatric disorders, most commonly depression, anxiety, and adjustment disorders. […] AA appears to be associated with atopy and many autoimmune diseases including vitiligo and thyroid disorders.
- #55 Homepage | Reflections of Alopecia Areatahttps://www.reflectionsofalopeciaareata.com/
Hair loss can be an emotional experience and it may be hard to talk about with others. Sharing feelings with a support system and dermatologist can help patients manage the diseases impact on everyday life. vii […] Up to 2 percent of the worlds population may experience alopecia areata in their lifetime i,ix […] 6.6 million people in the US may be diagnosed with alopecia areata in their lifetimes ix,x […] 80 percent of alopecia areata cases typically appear by age 40 vii […] Alopecia areata can have a real impact on patients daily lives and there can be an emotional burden. ii,xi […] Alopecia areata is an autoimmune disease that can affect all ages, genders, and ethnicities. Approximately 40% of patients experience their first episode of hair loss before the age of 20. xii
- #56https://www.johs.com.sa/pages/issue/abstract/?id=87
Hair loss affects self-image and is a significant contributor to anxiety and depression in some men, despite the fact that male androgenetic alopecia is frequently thought of as a relatively minor dermatological problem. […] Male androgenetic alopecia shows variable prevalence among different ages and ethnicities. Caucasians have much high reported prevalence than Asians. The prevalence of male androgenetic increases with age. […] About 50% of men experience male pattern hair loss or MAA which is an androgen-related disorder that affects people with certain genetic predispositions. […] MAA is a kind of alopecia that develops progressively after puberty. Alopecia is a physiological issue, but because it has a significant impact on aesthetics, it also has a significant impact on quality of life.
- #57 Female pattern hair losshttps://www1.racgp.org.au/ajgp/2018/july/female-pattern-hair-loss
Approximately 49% of women will be affected by hair loss throughout their lives, with female pattern hair loss (FPHL) being the most common cause of female alopecia. The incidence steadily increases with age in all ethnicities, and the age-adjusted prevalence among adult Australian women of European descent is 32%. This translates to 800,000 women who suffer from moderate-to-severe FPHL. […] One study found that patterned hair loss was an independent predictor of mortality from diabetes mellitus and heart disease in both females and males. Screening for metabolic cardiovascular risk factors is useful in patients presenting with patterned hair loss. […] The risk factors for FPHL include increasing age, family history, smoking, elevated fasting glucose levels and ultraviolet light exposure of 16 hours/week.
- #58 Female pattern hair losshttps://www1.racgp.org.au/ajgp/2018/july/female-pattern-hair-loss
FPHL is a common, non-scarring alopecia that affects women of all ages and carries significant psychological morbidity. It may be the first presenting complaint of hyperandrogenism, thyroid dysfunction or chronic deficient diet. A detailed history with appropriate laboratory testing to screen for associated cardiovascular disease, hypertension and metabolic syndrome is indicated.
- #59 Baldness: How close are we to a cure?https://www.medicalnewstoday.com/articles/317788
Existing medicines for treating hair loss have limited effectiveness and require ongoing use for the benefits of the treatment to continue. […] Researchers continue to strive for the holy grail of hair loss cures by trying to gain a better understanding of how the hair growth cycle is controlled. Rather than treating the symptoms of hair loss, scientists aim to target the cause, which, in turn, may yield fewer side effects. […] Not only could the teams findings help to predict a mans likelihood of experiencing severe hair loss, but they could also provide new targets for drug developments to treat baldness. […] We expect JAK inhibitors to have widespread utility across many forms of hair loss based on their mechanism of action in both the hair follicle and immune cells. […] Although giant strides to cure baldness are being made in laboratories globally, research is ongoing and the wait for a permanent solution continues.
- #60 Baldness: How close are we to a cure?https://www.medicalnewstoday.com/articles/317788
Existing medicines for treating hair loss have limited effectiveness and require ongoing use for the benefits of the treatment to continue. […] Researchers continue to strive for the holy grail of hair loss cures by trying to gain a better understanding of how the hair growth cycle is controlled. Rather than treating the symptoms of hair loss, scientists aim to target the cause, which, in turn, may yield fewer side effects. […] Not only could the teams findings help to predict a mans likelihood of experiencing severe hair loss, but they could also provide new targets for drug developments to treat baldness. […] We expect JAK inhibitors to have widespread utility across many forms of hair loss based on their mechanism of action in both the hair follicle and immune cells. […] Although giant strides to cure baldness are being made in laboratories globally, research is ongoing and the wait for a permanent solution continues.
- #61 Advancing Research on Alopecia Areata Treatment and Epidemiologyhttps://www.ajmc.com/view/advancing-research-on-alopecia-areata-treatment-and-epidemiology
Mostaghimi focuses on the progress made in understanding the epidemiology of alopecia areata and the development of new treatments but acknowledges the current obstacles that remain. […] We have a much greater understanding of the epidemiology of alopecia areata than we did years ago. Despite this, our epidemiology is at the level where we understand patterns at a population level, but we haven’t quite figured out variation between specific patients with regards to disease severity, response to therapy, and risk of relapse. […] Other open questions include whether or not earlier and more aggressive treatment of alopecia areata can prevent the development of comorbidities both psychiatric and otherwise. This is a real-world question that may inform patients on the fence about treatment.
- #62 Scarring Alopecia: Practice Essentials, Pathophysiology, Epidemiologyhttps://emedicine.medscape.com/article/1073559-overview
Population studies show a prevalence of 17.1% in African schoolgirls (6-21 y) and of 31.7% in women (18-86 y). […] Scarring alopecia prevalence studies are otherwise still lacking. Partial hindrance of such data production is based on the lack of well-established diagnostic criteria. […] Central centrifugal cicatricial alopecia is believed to be predominant in African Americans, while lichen planopilaris occurs mostly in lighter-skinned patients. […] The sex distribution of scarring alopecia is anecdotally believed to be predominantly favoring the female population. […] Traction alopecia is initially seen in children and young adults. […] However, in the African American population, this entity is a significant cause of alopecia. […] The exact frequency has yet to be documented in children, young adults, and adults. […] Age distribution on the other scarring alopecia types has not been well studied. The majority of case reports suggest these conditions present in persons older than 20 years.
- #63 Androgenetic Alopecia Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034https://www.researchandmarkets.com/reports/5969931/androgenetic-alopecia-market-epidemiology?srsltid=AfmBOopLqnOnDJAW8qtgKNF2ild9f1sNVY6MOx-zyt5LenAqDhm7gbOR
The androgenetic alopecia market has been comprehensively analyzed in this report titled „Androgenetic Alopecia Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034”. […] The increasing prevalence of severe hair loss and damage owing to sedentary lifestyles, unhealthy eating habits, and growing stress levels is primarily driving the androgenetic alopecia market. […] This report provides an exhaustive analysis of the androgenetic alopecia market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. […] According to the report the United States has the largest patient pool for androgenetic alopecia and also represents the largest market for its treatment. […] Historical, current, and future epidemiology scenario
- #64 Baldness: How close are we to a cure?https://www.medicalnewstoday.com/articles/317788
Existing medicines for treating hair loss have limited effectiveness and require ongoing use for the benefits of the treatment to continue. […] Researchers continue to strive for the holy grail of hair loss cures by trying to gain a better understanding of how the hair growth cycle is controlled. Rather than treating the symptoms of hair loss, scientists aim to target the cause, which, in turn, may yield fewer side effects. […] Not only could the teams findings help to predict a mans likelihood of experiencing severe hair loss, but they could also provide new targets for drug developments to treat baldness. […] We expect JAK inhibitors to have widespread utility across many forms of hair loss based on their mechanism of action in both the hair follicle and immune cells. […] Although giant strides to cure baldness are being made in laboratories globally, research is ongoing and the wait for a permanent solution continues.
- #65 Baldness: How close are we to a cure?https://www.medicalnewstoday.com/articles/317788
Existing medicines for treating hair loss have limited effectiveness and require ongoing use for the benefits of the treatment to continue. […] Researchers continue to strive for the holy grail of hair loss cures by trying to gain a better understanding of how the hair growth cycle is controlled. Rather than treating the symptoms of hair loss, scientists aim to target the cause, which, in turn, may yield fewer side effects. […] Not only could the teams findings help to predict a mans likelihood of experiencing severe hair loss, but they could also provide new targets for drug developments to treat baldness. […] We expect JAK inhibitors to have widespread utility across many forms of hair loss based on their mechanism of action in both the hair follicle and immune cells. […] Although giant strides to cure baldness are being made in laboratories globally, research is ongoing and the wait for a permanent solution continues.