Język geograficzny – Rokowania, prognozy i postęp choroby

Język geograficzny
Rokowania, prognozy i postęp choroby

Geograficzne zapalenie języka (benign migratory glossitis) to przewlekły, łagodny stan zapalny języka, charakteryzujący się okresami zaostrzeń i remisji oraz zmianami o charakterystycznym, mapowatym obrazie klinicznym. Schorzenie dotyka 2-3% dorosłej populacji, choć niektóre źródła podają częstość do 14%. Nie jest stanem nowotworowym i nie prowadzi do rozwoju raka jamy ustnej. Diagnostyka opiera się głównie na badaniu klinicznym, a badania laboratoryjne i biopsja zwykle nie są konieczne. W większości przypadków przebieg jest bezobjawowy i nie wymaga leczenia, choć w przypadku objawowego zapalenia stosuje się miejscowe terapie, np. takrolimus. Istotne jest monitorowanie pacjentów pod kątem współistniejącej łuszczycy, gdyż geograficzne zapalenie języka może być jej manifestacją i markerem ciężkości choroby, co potwierdza metaanaliza z OR 3,53 (95% CI 2,56-4,86).

Geograficzne zapalenie języka – Rokowanie

Naturalny przebieg choroby
Związek z łuszczycą i implikacje prognostyczne
Aspekty diagnostyczne wpływające na rokowanie
Perspektywa terapeutyczna
Przyszłe kierunki badań
Epidemiologia i znaczenie dla rokowania
Kolejne rozdziały

Geograficzne zapalenie języka – Rokowanie

Geograficzne zapalenie języka (benign migratory glossitis) jest łagodnym, przewlekłym stanem zapalnym języka o charakterystycznym obrazie klinicznym przypominającym mapę. Schorzenie to ma generalnie dobre rokowanie i w większości przypadków nie wymaga leczenia, ze względu na jego łagodny charakter i zazwyczaj bezobjawowy przebieg.¹²³

Naturalny przebieg choroby

Geograficzne zapalenie języka charakteryzuje się okresami zaostrzeń i remisji bez pozostawiania blizn. Zmiany mogą zmieniać swój rozmiar i kształt w czasie.⁴ W większości przypadków schorzenie ustępuje samoistnie z czasem, jednak niemożliwe jest przewidzenie, czy i kiedy to nastąpi.⁵⁶ Należy podkreślić, że geograficzne zapalenie języka:

Jest stanem nienowotworowym i nie prowadzi do rozwoju raka jamy ustnej⁷
Zazwyczaj nie wywołuje powikłań zdrowotnych⁸⁹
Charakteryzuje się nawrotowym przebiegiem – może ustąpić, ale często powraca¹⁰

Związek z łuszczycą i implikacje prognostyczne

Istotnym aspektem wpływającym na rokowanie jest udokumentowany związek między geograficznym zapaleniem języka a łuszczycą. Badania potwierdzają, że obecność geograficznego zapalenia języka może być predyktorem łuszczycy.¹¹¹² Metaanaliza wykazała, że iloraz szans (OR) dla tej zależności wynosi 3,53 (95% przedział ufności [CI] 2,56-4,86), co silnie wspiera koncepcję geograficznego zapalenia języka jako manifestacji łuszczycy.¹³

Z punktu widzenia rokowania, istotne konsekwencje tej zależności obejmują:

Pacjenci z łuszczycą i współistniejącym geograficznym zapaleniem języka wykazują mniejszą poprawę w skali PASI (Psoriasis Area and Severity Index) po leczeniu przeciwłuszczycowym¹⁴
Geograficzne zapalenie języka może stanowić marker ciężkości łuszczycy¹⁵
Jedno z badań wykazało związek między geograficznym zapaleniem języka a negatywnym wpływem na jakość życia pacjentów¹⁶

Interesującym aspektem prognostycznym jest również to, że geograficzne zapalenie języka opisywano jako wczesną manifestację łuszczycy, z późniejszą ewolucją do wariantu z bruzdami (fissured tongue), który może być trwały i/lub współistniejący z geograficznym zapaleniem języka u około 34,5% dotkniętych pacjentów.¹⁷

Aspekty diagnostyczne wpływające na rokowanie

Rozpoznanie geograficznego zapalenia języka jest zasadniczo kliniczne i opiera się na charakterystycznych objawach stwierdzanych podczas badania fizykalnego. Badania laboratoryjne są zwykle prawidłowe, a biopsja zmian zazwyczaj nie jest wymagana ze względu na łagodny charakter choroby.¹⁸ Lekarze diagnozują geograficzne zapalenie języka, pytając o objawy, takie jak bolesność języka lub czy plamy na języku ustępują i nawracają.¹⁹

Wczesna identyfikacja objawów geograficznego zapalenia języka prowadzi do lepszych wyników leczenia i większej satysfakcji pacjenta.²⁰ W kontekście rokowania, ważne jest podkreślenie, że:

Należy przeprowadzić dokładne badanie fizykalne u pacjentów z łuszczycą w poszukiwaniu zmian w jamie ustnej²¹
U pacjentów z geograficznym zapaleniem języka wskazane jest poszukiwanie zmian skórnych sugerujących łuszczycę²²

Perspektywa terapeutyczna

Nie istnieje leczenie eliminujące geograficzne zapalenie języka, chociaż lekarze mogą zalecać leki w przypadku objawowego przebiegu.²³ Biorąc pod uwagę sugerowany związek między alergiami lub atopią a geograficznym zapaleniem języka, rozważane są terapie korzystne dla pacjentów atopowych w leczeniu objawowego zapalenia języka, takie jak miejscowe stosowanie takrolimusu.²⁴

Zaproponowano również możliwe powiązanie między pacjentami atopowymi a hipowitaminozą D, sugerując, że suplementacja witaminą D mogłaby złagodzić objawy. Jednakże brak badań potwierdzających tę zależność w przypadku geograficznego zapalenia języka.²⁵

Przyszłe kierunki badań

Potrzebne są nowe kierunki badań, aby ustalić możliwe związki przyczynowo-skutkowe i relacje z ciężkością zmian językowych, a także aby zaoferować alternatywne metody leczenia pacjentom z objawowym i uporczywym geograficznym zapaleniem języka.²⁶²⁷ Przyszłe badania powinny koncentrować się na konsekwencjach geograficznego zapalenia języka u pacjentów z łuszczycą, ze względu na negatywny wpływ na ciężkość choroby i odpowiedź na leczenie.²⁸

Epidemiologia i znaczenie dla rokowania

Geograficzne zapalenie języka jest częstym schorzeniem, dotykającym 2-3% dorosłej populacji ogólnej, chociaż inne źródła podają częstość występowania do 14%.²⁹ Tak duża częstość występowania w populacji ogólnej wskazuje, że geograficzne zapalenie języka jest stosunkowo powszechnym zjawiskiem o generalnie łagodnym przebiegu i dobrym rokowaniu.

Warto podkreślić, że wielodyscyplinarny zespół, który zapewnia holistyczne i zintegrowane podejście do diagnostyki i leczenia geograficznego zapalenia języka, może pomóc w osiągnięciu najlepszych możliwych wyników.³⁰

Kolejne rozdziały

Zapraszamy do dalszego czytania naszego leksykonu.

Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.

Materiały źródłowe

#1 Geographic Tongue – StatPearls – NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK554466/
Geographic tongue is a benign usually asymptomatic condition with a good prognosis.[1] […] Geographic tongue usually does not have any complications.[1] […] An interprofessional team that provides a holistic and integrated approach to diagnosing and treating geographic tongue can help achieve the best possible outcomes. […] The earlier signs and symptoms of geographic tongue are identified; the better is the patient outcome and satisfaction.
#2 Geographic tongue (Benign migratory glossitis): An Overview with Images â DermNet
https://dermnetnz.org/topics/geographic-tongue
The outcome of geographic tongue is good. In most cases, it resolves over time without treatment.
#3 Geographic Tongue: What a Dermatologist Should Know | Actas Dermo-SifiliogrÃ¡ficas
https://www.actasdermo.org/en-geographic-tongue-what-dermatologist-should-articulo-S1578219019301489
Geographic tongue, also known as benign migratory glossitis, is a benign chronic inflammatory condition of the tongue. It is characterized by erythematous lesions with filiform papillae atrophy, surrounded by white limited areas in the dorsal and lateral aspects of the tongue, producing a map-like aspect. This lesions change in size and shape with time, and are characterized by periods of exacerbation and remission without scaring. The cause is unknown, but multiple associations have been described, which will be discussed below. […] The diagnosis of benign migratory glossitis is essentially clinical. Laboratory tests are usually normal and, in general terms, lesion biopsy is not required given the benign nature of the disease. […] The geographical tongue or migratory glossitis is a benign and chronic inflammatory condition of the tongue, with no known cause. The diagnosis is made essentially with clinical resources, with characteristic findings on physical examination. It usually does not require treatment, given its benign condition and asymptomatic course.
#4 Geographic Tongue: What a Dermatologist Should Know | Actas Dermo-SifiliogrÃ¡ficas
https://www.actasdermo.org/en-geographic-tongue-what-dermatologist-should-articulo-S1578219019301489
Geographic tongue, also known as benign migratory glossitis, is a benign chronic inflammatory condition of the tongue. It is characterized by erythematous lesions with filiform papillae atrophy, surrounded by white limited areas in the dorsal and lateral aspects of the tongue, producing a map-like aspect. This lesions change in size and shape with time, and are characterized by periods of exacerbation and remission without scaring. The cause is unknown, but multiple associations have been described, which will be discussed below. […] The diagnosis of benign migratory glossitis is essentially clinical. Laboratory tests are usually normal and, in general terms, lesion biopsy is not required given the benign nature of the disease. […] The geographical tongue or migratory glossitis is a benign and chronic inflammatory condition of the tongue, with no known cause. The diagnosis is made essentially with clinical resources, with characteristic findings on physical examination. It usually does not require treatment, given its benign condition and asymptomatic course.
#5 Geographic tongue – Wikipedia
https://en.wikipedia.org/wiki/Geographic_tongue
The condition may disappear over time, but it is impossible to predict if or when this may happen. […] Geographic tongue is a common condition, affecting 2-3% of the adult general population, although other sources report a prevalence of up to 14%. […] A recent study has proven the link between geographic tongue (GT) and psoriasis – the presence of geographic tongue can be a predictor of psoriasis.
#6 Geographic tongue (Benign migratory glossitis): An Overview with Images â DermNet
https://dermnetnz.org/topics/geographic-tongue
The outcome of geographic tongue is good. In most cases, it resolves over time without treatment.
#7 Geographic Tongue: Causes, Symptoms & Treatment
https://my.clevelandclinic.org/health/diseases/21177-geographic-tongue
Geographic tongue is a noncancerous condition that causes smooth reddish, patches on your tongue. Geographic tongue is noncancerous, doesnt cause health issues and doesnt require treatment. […] Geographic tongue is a non-cancerous condition that creates patches of smooth reddish skin on your tongue. Geographic tongue is benign, meaning it doesnt spread. […] Geographic tongue isnt painful and its not serious. […] Healthcare providers arent sure what causes the condition. […] Healthcare providers diagnose geographic tongue by asking about your symptoms, such as whether your tongue hurts or if the patches on your tongue go away and come back. […] Theres no treatment to eliminate geographic tongue, but healthcare providers may recommend medication. […] Probably not. Healthcare providers arent sure what causes geographic tongue, but they believe people with certain conditions, like diabetes or skin issues, have increased risk of developing geographic tongue. […] No, it cant be cured. Geographic tongue often goes away on its own without treatment, but it can come back. […] No, geographic tongue is a noncancerous disorder that doesnt become oral cancer.
#8 Geographic Tongue – StatPearls – NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK554466/
Geographic tongue is a benign usually asymptomatic condition with a good prognosis.[1] […] Geographic tongue usually does not have any complications.[1] […] An interprofessional team that provides a holistic and integrated approach to diagnosing and treating geographic tongue can help achieve the best possible outcomes. […] The earlier signs and symptoms of geographic tongue are identified; the better is the patient outcome and satisfaction.
#9 Geographic Tongue: Causes, Symptoms & Treatment
https://my.clevelandclinic.org/health/diseases/21177-geographic-tongue
Geographic tongue is a noncancerous condition that causes smooth reddish, patches on your tongue. Geographic tongue is noncancerous, doesnt cause health issues and doesnt require treatment. […] Geographic tongue is a non-cancerous condition that creates patches of smooth reddish skin on your tongue. Geographic tongue is benign, meaning it doesnt spread. […] Geographic tongue isnt painful and its not serious. […] Healthcare providers arent sure what causes the condition. […] Healthcare providers diagnose geographic tongue by asking about your symptoms, such as whether your tongue hurts or if the patches on your tongue go away and come back. […] Theres no treatment to eliminate geographic tongue, but healthcare providers may recommend medication. […] Probably not. Healthcare providers arent sure what causes geographic tongue, but they believe people with certain conditions, like diabetes or skin issues, have increased risk of developing geographic tongue. […] No, it cant be cured. Geographic tongue often goes away on its own without treatment, but it can come back. […] No, geographic tongue is a noncancerous disorder that doesnt become oral cancer.
#10 Geographic Tongue: Causes, Symptoms & Treatment
https://my.clevelandclinic.org/health/diseases/21177-geographic-tongue
Geographic tongue is a noncancerous condition that causes smooth reddish, patches on your tongue. Geographic tongue is noncancerous, doesnt cause health issues and doesnt require treatment. […] Geographic tongue is a non-cancerous condition that creates patches of smooth reddish skin on your tongue. Geographic tongue is benign, meaning it doesnt spread. […] Geographic tongue isnt painful and its not serious. […] Healthcare providers arent sure what causes the condition. […] Healthcare providers diagnose geographic tongue by asking about your symptoms, such as whether your tongue hurts or if the patches on your tongue go away and come back. […] Theres no treatment to eliminate geographic tongue, but healthcare providers may recommend medication. […] Probably not. Healthcare providers arent sure what causes geographic tongue, but they believe people with certain conditions, like diabetes or skin issues, have increased risk of developing geographic tongue. […] No, it cant be cured. Geographic tongue often goes away on its own without treatment, but it can come back. […] No, geographic tongue is a noncancerous disorder that doesnt become oral cancer.
#11 Geographic tongue – Wikipedia
https://en.wikipedia.org/wiki/Geographic_tongue
The condition may disappear over time, but it is impossible to predict if or when this may happen. […] Geographic tongue is a common condition, affecting 2-3% of the adult general population, although other sources report a prevalence of up to 14%. […] A recent study has proven the link between geographic tongue (GT) and psoriasis – the presence of geographic tongue can be a predictor of psoriasis.
#12 Association between geographic tongue and psoriasis: A systematic review and meta-analyses – PubMed
https://pubmed.ncbi.nlm.nih.gov/30739339/
Geographic tongue (GT) has been described as a predictor of psoriasis. […] The pooled odds ratio (OR) was 3.53 (95% confidence interval [CI] 2.56-4.86). […] Psoriatic patients with GT also exhibited less improvement in the PASI score after treatment. […] One study found an association between GT and a negative impact on patients’ quality of life. […] The results support the concept of GT as a manifestation of psoriasis. […] Future research should focus on the repercussions of GT in psoriatic patients, due to the negative consequences on severity and treatment response.
#13 Association between geographic tongue and psoriasis: A systematic review and meta-analyses – PubMed
https://pubmed.ncbi.nlm.nih.gov/30739339/
Geographic tongue (GT) has been described as a predictor of psoriasis. […] The pooled odds ratio (OR) was 3.53 (95% confidence interval [CI] 2.56-4.86). […] Psoriatic patients with GT also exhibited less improvement in the PASI score after treatment. […] One study found an association between GT and a negative impact on patients’ quality of life. […] The results support the concept of GT as a manifestation of psoriasis. […] Future research should focus on the repercussions of GT in psoriatic patients, due to the negative consequences on severity and treatment response.
#14 Association between geographic tongue and psoriasis: A systematic review and meta-analyses – PubMed
https://pubmed.ncbi.nlm.nih.gov/30739339/
Geographic tongue (GT) has been described as a predictor of psoriasis. […] The pooled odds ratio (OR) was 3.53 (95% confidence interval [CI] 2.56-4.86). […] Psoriatic patients with GT also exhibited less improvement in the PASI score after treatment. […] One study found an association between GT and a negative impact on patients’ quality of life. […] The results support the concept of GT as a manifestation of psoriasis. […] Future research should focus on the repercussions of GT in psoriatic patients, due to the negative consequences on severity and treatment response.
#15 Geographic Tongue: What a Dermatologist Should Know | Actas Dermo-SifiliogrÃ¡ficas
https://www.actasdermo.org/en-geographic-tongue-what-dermatologist-should-articulo-S1578219019301489
Although there are no studies that aim at geographic tongue associations with certain pathologies and/or clinical conditions, it is possible to highlight some important aspects of these. First place, a considerable number of studies support the relationship between geographical tongue and psoriasis, showing a histological similarity and a common genetic marker. In this context, it is important to perform a thorough physical examination of patients with psoriasis in search of oral lesions, which if present, can constitute a marker of severity. In the same way, in patients with migratory glossitis, it is advisable to investigate in search of cutaneous lesions suggestive of psoriasis. […] New lines of research are required to establish possible causality and relationship with severity of the lingual manifestations, as well to offer other treatment alternatives to patients with symptomatic and persistent migratory glossitis.
#16 Association between geographic tongue and psoriasis: A systematic review and meta-analyses – PubMed
https://pubmed.ncbi.nlm.nih.gov/30739339/
Geographic tongue (GT) has been described as a predictor of psoriasis. […] The pooled odds ratio (OR) was 3.53 (95% confidence interval [CI] 2.56-4.86). […] Psoriatic patients with GT also exhibited less improvement in the PASI score after treatment. […] One study found an association between GT and a negative impact on patients’ quality of life. […] The results support the concept of GT as a manifestation of psoriasis. […] Future research should focus on the repercussions of GT in psoriatic patients, due to the negative consequences on severity and treatment response.
#17 Geographic Tongue: What a Dermatologist Should Know | Actas Dermo-SifiliogrÃ¡ficas
https://actasdermo.org/en-geographic-tongue-what-dermatologist-should-articulo-S1578219019301489
Geographic tongue, also known as benign migratory glossitis, is a benign chronic inflammatory condition of the tongue. It is characterized by erythematous lesions with filiform papillae atrophy, surrounded by white limited areas in the dorsal and lateral aspects of the tongue, producing a map-like aspect. This lesions change in size and shape with time, and are characterized by periods of exacerbation and remission without scaring. The cause is unknown, but multiple associations have been described, which will be discussed below. […] Geographic tongue has been described as an early manifestation of psoriasis, with late evolution into the fissured variant, which could be permanent and/or concomitant with geographic tongue up to a 34.5% of affected patients. […] The geographical tongue or migratory glossitis is a benign and chronic inflammatory condition of the tongue, with no known cause. The diagnosis is made essentially with clinical resources, with characteristic findings on physical examination. It usually does not require treatment, given its benign condition and asymptomatic course.
#18 Geographic Tongue: What a Dermatologist Should Know | Actas Dermo-SifiliogrÃ¡ficas
https://www.actasdermo.org/en-geographic-tongue-what-dermatologist-should-articulo-S1578219019301489
Geographic tongue, also known as benign migratory glossitis, is a benign chronic inflammatory condition of the tongue. It is characterized by erythematous lesions with filiform papillae atrophy, surrounded by white limited areas in the dorsal and lateral aspects of the tongue, producing a map-like aspect. This lesions change in size and shape with time, and are characterized by periods of exacerbation and remission without scaring. The cause is unknown, but multiple associations have been described, which will be discussed below. […] The diagnosis of benign migratory glossitis is essentially clinical. Laboratory tests are usually normal and, in general terms, lesion biopsy is not required given the benign nature of the disease. […] The geographical tongue or migratory glossitis is a benign and chronic inflammatory condition of the tongue, with no known cause. The diagnosis is made essentially with clinical resources, with characteristic findings on physical examination. It usually does not require treatment, given its benign condition and asymptomatic course.
#19 Geographic Tongue: Causes, Symptoms & Treatment
https://my.clevelandclinic.org/health/diseases/21177-geographic-tongue
Geographic tongue is a noncancerous condition that causes smooth reddish, patches on your tongue. Geographic tongue is noncancerous, doesnt cause health issues and doesnt require treatment. […] Geographic tongue is a non-cancerous condition that creates patches of smooth reddish skin on your tongue. Geographic tongue is benign, meaning it doesnt spread. […] Geographic tongue isnt painful and its not serious. […] Healthcare providers arent sure what causes the condition. […] Healthcare providers diagnose geographic tongue by asking about your symptoms, such as whether your tongue hurts or if the patches on your tongue go away and come back. […] Theres no treatment to eliminate geographic tongue, but healthcare providers may recommend medication. […] Probably not. Healthcare providers arent sure what causes geographic tongue, but they believe people with certain conditions, like diabetes or skin issues, have increased risk of developing geographic tongue. […] No, it cant be cured. Geographic tongue often goes away on its own without treatment, but it can come back. […] No, geographic tongue is a noncancerous disorder that doesnt become oral cancer.
#20 Geographic Tongue – StatPearls – NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK554466/
Geographic tongue is a benign usually asymptomatic condition with a good prognosis.[1] […] Geographic tongue usually does not have any complications.[1] […] An interprofessional team that provides a holistic and integrated approach to diagnosing and treating geographic tongue can help achieve the best possible outcomes. […] The earlier signs and symptoms of geographic tongue are identified; the better is the patient outcome and satisfaction.
#21 Geographic Tongue: What a Dermatologist Should Know | Actas Dermo-SifiliogrÃ¡ficas
https://www.actasdermo.org/en-geographic-tongue-what-dermatologist-should-articulo-S1578219019301489
Although there are no studies that aim at geographic tongue associations with certain pathologies and/or clinical conditions, it is possible to highlight some important aspects of these. First place, a considerable number of studies support the relationship between geographical tongue and psoriasis, showing a histological similarity and a common genetic marker. In this context, it is important to perform a thorough physical examination of patients with psoriasis in search of oral lesions, which if present, can constitute a marker of severity. In the same way, in patients with migratory glossitis, it is advisable to investigate in search of cutaneous lesions suggestive of psoriasis. […] New lines of research are required to establish possible causality and relationship with severity of the lingual manifestations, as well to offer other treatment alternatives to patients with symptomatic and persistent migratory glossitis.
#22 Geographic Tongue: What a Dermatologist Should Know | Actas Dermo-SifiliogrÃ¡ficas
https://www.actasdermo.org/en-geographic-tongue-what-dermatologist-should-articulo-S1578219019301489
Although there are no studies that aim at geographic tongue associations with certain pathologies and/or clinical conditions, it is possible to highlight some important aspects of these. First place, a considerable number of studies support the relationship between geographical tongue and psoriasis, showing a histological similarity and a common genetic marker. In this context, it is important to perform a thorough physical examination of patients with psoriasis in search of oral lesions, which if present, can constitute a marker of severity. In the same way, in patients with migratory glossitis, it is advisable to investigate in search of cutaneous lesions suggestive of psoriasis. […] New lines of research are required to establish possible causality and relationship with severity of the lingual manifestations, as well to offer other treatment alternatives to patients with symptomatic and persistent migratory glossitis.
#23 Geographic Tongue: Causes, Symptoms & Treatment
https://my.clevelandclinic.org/health/diseases/21177-geographic-tongue
Geographic tongue is a noncancerous condition that causes smooth reddish, patches on your tongue. Geographic tongue is noncancerous, doesnt cause health issues and doesnt require treatment. […] Geographic tongue is a non-cancerous condition that creates patches of smooth reddish skin on your tongue. Geographic tongue is benign, meaning it doesnt spread. […] Geographic tongue isnt painful and its not serious. […] Healthcare providers arent sure what causes the condition. […] Healthcare providers diagnose geographic tongue by asking about your symptoms, such as whether your tongue hurts or if the patches on your tongue go away and come back. […] Theres no treatment to eliminate geographic tongue, but healthcare providers may recommend medication. […] Probably not. Healthcare providers arent sure what causes geographic tongue, but they believe people with certain conditions, like diabetes or skin issues, have increased risk of developing geographic tongue. […] No, it cant be cured. Geographic tongue often goes away on its own without treatment, but it can come back. […] No, geographic tongue is a noncancerous disorder that doesnt become oral cancer.
#24 Geographic Tongue: What a Dermatologist Should Know | Actas Dermo-SifiliogrÃ¡ficas
https://actasdermo.org/en-geographic-tongue-what-dermatologist-should-articulo-S1578219019301489
Although there are no studies that aim at geographic tongue associations with certain pathologies and/or clinical conditions, it is possible to highlight some important aspects of these. First place, a considerable number of studies support the relationship between geographical tongue and psoriasis, showing a histological similarity and a common genetic marker. In this context, it is important to perform a thorough physical examination of patients with psoriasis in search of oral lesions, which if present, can constitute a marker of severity. In the same way, in patients with migratory glossitis, it is advisable to investigate in search of cutaneous lesions suggestive of psoriasis. […] Regarding the existing relationship between allergies or atopy and geographical tongue, it could be useful to consider therapies that are beneficial in atopic patients for the treatment of symptomatic glossitis, such as the use of topical tacrolimus. Along these lines, a possible association between atopic patients and hypovitaminosis D has been proposed, so it has been suggested that supplementation with vitamin D could reduce its symptoms. However, there are no studies that demonstrate this relationship with migratory glossitis. New lines of research are required to establish possible causality and relationship with severity of the lingual manifestations, as well to offer other treatment alternatives to patients with symptomatic and persistent migratory glossitis.
#25 Geographic Tongue: What a Dermatologist Should Know | Actas Dermo-SifiliogrÃ¡ficas
https://actasdermo.org/en-geographic-tongue-what-dermatologist-should-articulo-S1578219019301489
Although there are no studies that aim at geographic tongue associations with certain pathologies and/or clinical conditions, it is possible to highlight some important aspects of these. First place, a considerable number of studies support the relationship between geographical tongue and psoriasis, showing a histological similarity and a common genetic marker. In this context, it is important to perform a thorough physical examination of patients with psoriasis in search of oral lesions, which if present, can constitute a marker of severity. In the same way, in patients with migratory glossitis, it is advisable to investigate in search of cutaneous lesions suggestive of psoriasis. […] Regarding the existing relationship between allergies or atopy and geographical tongue, it could be useful to consider therapies that are beneficial in atopic patients for the treatment of symptomatic glossitis, such as the use of topical tacrolimus. Along these lines, a possible association between atopic patients and hypovitaminosis D has been proposed, so it has been suggested that supplementation with vitamin D could reduce its symptoms. However, there are no studies that demonstrate this relationship with migratory glossitis. New lines of research are required to establish possible causality and relationship with severity of the lingual manifestations, as well to offer other treatment alternatives to patients with symptomatic and persistent migratory glossitis.
#26 Geographic Tongue: What a Dermatologist Should Know | Actas Dermo-SifiliogrÃ¡ficas
https://actasdermo.org/en-geographic-tongue-what-dermatologist-should-articulo-S1578219019301489
Although there are no studies that aim at geographic tongue associations with certain pathologies and/or clinical conditions, it is possible to highlight some important aspects of these. First place, a considerable number of studies support the relationship between geographical tongue and psoriasis, showing a histological similarity and a common genetic marker. In this context, it is important to perform a thorough physical examination of patients with psoriasis in search of oral lesions, which if present, can constitute a marker of severity. In the same way, in patients with migratory glossitis, it is advisable to investigate in search of cutaneous lesions suggestive of psoriasis. […] Regarding the existing relationship between allergies or atopy and geographical tongue, it could be useful to consider therapies that are beneficial in atopic patients for the treatment of symptomatic glossitis, such as the use of topical tacrolimus. Along these lines, a possible association between atopic patients and hypovitaminosis D has been proposed, so it has been suggested that supplementation with vitamin D could reduce its symptoms. However, there are no studies that demonstrate this relationship with migratory glossitis. New lines of research are required to establish possible causality and relationship with severity of the lingual manifestations, as well to offer other treatment alternatives to patients with symptomatic and persistent migratory glossitis.
#27 Geographic Tongue: What a Dermatologist Should Know | Actas Dermo-SifiliogrÃ¡ficas
https://www.actasdermo.org/en-geographic-tongue-what-dermatologist-should-articulo-S1578219019301489
Although there are no studies that aim at geographic tongue associations with certain pathologies and/or clinical conditions, it is possible to highlight some important aspects of these. First place, a considerable number of studies support the relationship between geographical tongue and psoriasis, showing a histological similarity and a common genetic marker. In this context, it is important to perform a thorough physical examination of patients with psoriasis in search of oral lesions, which if present, can constitute a marker of severity. In the same way, in patients with migratory glossitis, it is advisable to investigate in search of cutaneous lesions suggestive of psoriasis. […] New lines of research are required to establish possible causality and relationship with severity of the lingual manifestations, as well to offer other treatment alternatives to patients with symptomatic and persistent migratory glossitis.
#28 Association between geographic tongue and psoriasis: A systematic review and meta-analyses – PubMed
https://pubmed.ncbi.nlm.nih.gov/30739339/
Geographic tongue (GT) has been described as a predictor of psoriasis. […] The pooled odds ratio (OR) was 3.53 (95% confidence interval [CI] 2.56-4.86). […] Psoriatic patients with GT also exhibited less improvement in the PASI score after treatment. […] One study found an association between GT and a negative impact on patients’ quality of life. […] The results support the concept of GT as a manifestation of psoriasis. […] Future research should focus on the repercussions of GT in psoriatic patients, due to the negative consequences on severity and treatment response.
#29 Geographic tongue – Wikipedia
https://en.wikipedia.org/wiki/Geographic_tongue
The condition may disappear over time, but it is impossible to predict if or when this may happen. […] Geographic tongue is a common condition, affecting 2-3% of the adult general population, although other sources report a prevalence of up to 14%. […] A recent study has proven the link between geographic tongue (GT) and psoriasis – the presence of geographic tongue can be a predictor of psoriasis.
#30 Geographic Tongue – StatPearls – NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK554466/
Geographic tongue is a benign usually asymptomatic condition with a good prognosis.[1] […] Geographic tongue usually does not have any complications.[1] […] An interprofessional team that provides a holistic and integrated approach to diagnosing and treating geographic tongue can help achieve the best possible outcomes. […] The earlier signs and symptoms of geographic tongue are identified; the better is the patient outcome and satisfaction.