Materiały źródłowe

• #1 Ménière’s Disease: Epidemiology | IntechOpen

  https://www.intechopen.com/chapters/56186

  Menieres disease is a disorder of the membranous labyrinth of the inner ear manifesting as vertigo, tinnitus, sensory neural hearing loss and aural fullness of known or unknown origin. The aim of this chapter is to estimate the prevalence of Mnires disease (MD) and its relationship with demographic factors, symptoms and conditions that are known. Few articles have been published on the epidemiology of Menieres disease from 1975 to 1990, studies from Japan indicated a fairly constant prevalence of 17 cases per 100,000 population. […] Kotimaki and colleagues analysed the Finnish population of five million people between 1992 and 1996. A prevalence of 43/100,000 and an average yearly incidence of 4.3/100,000 population were found by the authors. MD is 13 times higher in women than in men and also observed a higher prevalence in adulthood and white people. […] However, in recent years, especially in the last decades, there have been several safe and effective medical and surgical therapies for the treatment of the disease and its sequels.

• #2 Ménière’s Disease: Epidemiology | IntechOpen

  https://www.intechopen.com/chapters/56186

  Despite the large number of scientific contributions published annually on Menieres disease, consistent epidemiologic information is sparse. To date, the true incidence and prevalence of Menieres disease are not known. […] Although Mnires syndrome (MS) has been recognized as a clinical entity since 1861, when it was first described by Prosper Mnire, the epidemiology of the disorder is still uncertain. […] Many of the epidemiologic studies have to rely on chart reviews or medical databases, each having their own flaws. […] Published reports of the epidemiology of MS generally fall into two methodological categories. Most published studies are retrospective series that start with known cases of MS identified from patient records for a given group of hospitals and clinics. The population served by the hospitals and clinics then serves as the dominator for calculating incidence and prevalence.

• #3 Meniere Disease – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK536955/

  The prevalence of Meniere disease varies between 3.5 per 100.000 and 513 per 100.000 and occurs more often in older, white, female patients. […] Several comorbidities have been identified which occur in an increased fashion in patients with Meniere disease: […] Migraine occurs more often in patients diagnosed with Meniere disease, although there is likely significant overlap/misclassification of patients with basilar migraine wrongly diagnosed as having Meniere disease. […] Several autoimmune diseases are associated with Meniere disease, namely rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis. […] Meniere disease is a polygenic disorder. Ten percent of cases in patients of European descent have familial Meniere disease. […] The Brny Society published the current classification of Meniere disease. It is essential to base the diagnosis of Meniere disease on the criteria published and mentioned in this article to warrant a uniform diagnosis, especially in the presence of different international approaches to diagnosing patients with vertigo.

• #4 Ménière’s Disease: Epidemiology | IntechOpen

  https://www.intechopen.com/chapters/56186

  Menieres disease is a disorder of the membranous labyrinth of the inner ear manifesting as vertigo, tinnitus, sensory neural hearing loss and aural fullness of known or unknown origin. The aim of this chapter is to estimate the prevalence of Mnires disease (MD) and its relationship with demographic factors, symptoms and conditions that are known. Few articles have been published on the epidemiology of Menieres disease from 1975 to 1990, studies from Japan indicated a fairly constant prevalence of 17 cases per 100,000 population. […] Kotimaki and colleagues analysed the Finnish population of five million people between 1992 and 1996. A prevalence of 43/100,000 and an average yearly incidence of 4.3/100,000 population were found by the authors. MD is 13 times higher in women than in men and also observed a higher prevalence in adulthood and white people. […] However, in recent years, especially in the last decades, there have been several safe and effective medical and surgical therapies for the treatment of the disease and its sequels.

• #5 Epidemiology of Meniere’s disease

  https://www.dizziness-and-balance.com/disorders/menieres/epidem.html

  Epidemiology of Menieres Disease […] To summarize, it appears that that Meniere’s disease has a prevalence of approximately 200 cases/100,000 persons in the United States, or in other words, less than 0.2 % of the population has Meniere’s disease. The prevalence may vary internationally, possibly being lower by as much as a factor of 10 in some populations, but it seems more likely that the numbers vary so much due to difference in criteria and reporting. The prevalence increases with age, rather linearly, up to the age of 60. Men and women are approximately equal in number. […] In Finland, prevalence was reported to be 43/100,000 and incidence was 4.3/100,000 (Kotimaki et al, 1999). This figure appears low compared to the United States and England. On the other hand, Havia et al (2005) reported a prevalence of 513/100K. This is much higher than most.

• #6 Meniere Disease | Ento Key

  https://entokey.com/meniere-disease/

  Meniere disease is defined by a group of symptoms including fluctuating sensorineural hearing loss, episodic vertigo, tinnitus, and aural fullness. […] The epidemiology, pathophysiology, clinical presentation, and treatment options will be reviewed. […] There is a wide range of reports on Meniere disease prevalence in the literature. This is likely because of both a variance in presentation and difficulty in diagnosis. […] Harris and Alexander examined a large health claims database, comprising over 60 million insured patients from 97 health plans, to estimate the number of patients who carried an International Classification of Diseases-9 coded diagnosis of Meniere disease. They concluded there to be an estimated prevalence of 190 per 100,000. […] The most often cited study regarding Meniere disease prevalence is Waserman et al, which demonstrated a prevalence of 218 per 100,000.

• #7 Meniere Disease (Idiopathic Endolymphatic Hydrops): Background, Anatomy, Pathophysiology

  https://emedicine.medscape.com/article/1159069-overview

  In the United States, a prevalence of 1,000 cases of endolymphatic hydrops per 100,000 population is a reasonable approximation, though it is probably an underestimate. Familial predisposition may be a factor, since half of patients have a significant family history. […] The reported prevalence of Mnire disease (ie, idiopathic endolymphatic hydrops) varies widely, from 15 per 100,000 in the United States to 157 per 100,000 in the United Kingdom. […] Bilateral disease is found in 10% of patients with Mnire disease at initial diagnosis; with disease progression, it may be found in more than 40%. […] Mnire disease can be seen at almost all ages: it has been described in children as young as 4 years and in elderly persons older than 90 years. […] The peak incidence of Mnires disease is in the 40- to 60-year-old age group.

• #8 Ménière’s Disease: Epidemiology | IntechOpen

  https://www.intechopen.com/chapters/56186

  Menieres disease is a disorder of the membranous labyrinth of the inner ear manifesting as vertigo, tinnitus, sensory neural hearing loss and aural fullness of known or unknown origin. The aim of this chapter is to estimate the prevalence of Mnires disease (MD) and its relationship with demographic factors, symptoms and conditions that are known. Few articles have been published on the epidemiology of Menieres disease from 1975 to 1990, studies from Japan indicated a fairly constant prevalence of 17 cases per 100,000 population. […] Kotimaki and colleagues analysed the Finnish population of five million people between 1992 and 1996. A prevalence of 43/100,000 and an average yearly incidence of 4.3/100,000 population were found by the authors. MD is 13 times higher in women than in men and also observed a higher prevalence in adulthood and white people. […] However, in recent years, especially in the last decades, there have been several safe and effective medical and surgical therapies for the treatment of the disease and its sequels.

• #9 Epidemiology of Meniere’s disease

  https://www.dizziness-and-balance.com/disorders/menieres/epidem.html

  Epidemiology of Menieres Disease […] To summarize, it appears that that Meniere’s disease has a prevalence of approximately 200 cases/100,000 persons in the United States, or in other words, less than 0.2 % of the population has Meniere’s disease. The prevalence may vary internationally, possibly being lower by as much as a factor of 10 in some populations, but it seems more likely that the numbers vary so much due to difference in criteria and reporting. The prevalence increases with age, rather linearly, up to the age of 60. Men and women are approximately equal in number. […] In Finland, prevalence was reported to be 43/100,000 and incidence was 4.3/100,000 (Kotimaki et al, 1999). This figure appears low compared to the United States and England. On the other hand, Havia et al (2005) reported a prevalence of 513/100K. This is much higher than most.

• #10 Ménière’s Disease: Epidemiology | IntechOpen

  https://www.intechopen.com/chapters/56186

  In 1973, Stahle and colleagues reported a prevalence of 46 cases per 100,000 population. From 1975 to 1990, studies from Japan indicated a fairly constant prevalence of 17 cases per 100,000 population. […] Kotimaki and colleagues reported a prevalence of 43/100,000 and an average annual incidence of 4/3,000,000 inhabitants after analysing the Finnish population for a period of 4 years according to the AAOHNS recommendations. […] Estimated prevalence rates range from as low as 3.5 per 100,000 population to as high as 513 per 100,000 population. However, it is clear that Mnires disease is more common in women. […] Most studies suggest a slight female preponderance of up to 1.3 times that of men. MD seems to be much more common in white adults with higher body mass index categories, in their fourth and fifth decade.

• #11 Ménière’s Disease: Epidemiology | IntechOpen

  https://www.intechopen.com/chapters/56186

  In 1973, Stahle and colleagues reported a prevalence of 46 cases per 100,000 population. From 1975 to 1990, studies from Japan indicated a fairly constant prevalence of 17 cases per 100,000 population. […] Kotimaki and colleagues reported a prevalence of 43/100,000 and an average annual incidence of 4/3,000,000 inhabitants after analysing the Finnish population for a period of 4 years according to the AAOHNS recommendations. […] Estimated prevalence rates range from as low as 3.5 per 100,000 population to as high as 513 per 100,000 population. However, it is clear that Mnires disease is more common in women. […] Most studies suggest a slight female preponderance of up to 1.3 times that of men. MD seems to be much more common in white adults with higher body mass index categories, in their fourth and fifth decade.

• #12 Ménière’s Disease – American Hearing Research Foundation

  https://www.american-hearing.org/disease/menieres-disease/

  Mnires disease (Menieres) is a disorder of the inner ear that sometimes seems to carry with it more questions than answers. In recent years, however, the scientific and medical communitys understanding of Mnires has increased significantly. Although there still is no cure, medical professionals are now better able to advise and treat people with the disorder to help them manage its symptoms. […] Mnires affects roughly 615,000 people in the United States, making it a relatively rare disorder, according to current statistics. About 0.2 percent of the U.S. population has it. And each year about 45,500 new cases are diagnosed. But despite these statistics, there continues to be debate over how common Menieres actually is. […] Although it can come on at any age, most people with Mnires are 40 or older. Onset most often occurs between 40 and 60. And the probability of developing the disorder is fairly equal between both women and men, although some studies do show that women may be more likely to be diagnosed with it.

• #13 Meniere’s Disease and the Pharmacist

  https://www.uspharmacist.com/article/menieres-disease-and-the-pharmacist

  According to the National Institute on Deafness and Other Communication Disorders (NIDCD), approximately 615,000 adults have been diagnosed with Menieres in the United States, but at least 45,000 to 100,000 new cases are diagnosed each year. However, other authorities quote the prevalence rates in the U.S. to vary from as few as 3.5 patients per 100,000 to as many as 513 per 100,000. […] The onset of Menieres can be felt at any age. However, the primary ages of attack are between 40 and 60 years, and 10% of those aged 65 years or older have Menieres. There is a female-to-male ratio of 1.89:1. Menieres may also occur with more frequency in patients who abuse alcohol or tobacco, are stressed or fatigued, and have allergies.

• #14 Ménière’s Disease: Symptoms and Treatment

  https://patient.info/doctor/menieres-disease-pro

  It is hard to estimate incidence and prevalence due to the episodic nature of the disorder but Mnire’s is an uncommon cause of vertigo. […] A population-based UK study found an overall incidence rate of 13.1 per 100,000 person-years, with the diagnosis more common in women. […] The diagnosis of Mnire’s disease is most commonly made in people aged 40-50 years. […] The condition is probably rare in children but has been reported in this age group.

• #15 Population-Based Study on the Epidemiology of Meniere’s Disease. – CzeekV インデックス

  https://czeek.com/ronbun/population-based-study-on-the-epidemiology-of-menieres-disease/

  Population-Based Study on the Epidemiology of Menieres Disease. […] Meniere’s disease (MD) is a disorder of the inner ear typically showing recurrent acute episodes of vertigo, hearing loss, and tinnitus. Epidemiologic studies on MD are scarce. […] We assessed the incidence rates (IRs) of MD and describe the characteristics of MD cases, comparing them to control patients without recorded evidence of MD. […] We identified 5,508 MD cases and 22,032 MD-free controls (65.4% females). The overall IR for MD in the UK was 13.1 per 100,000 person-years. […] MD is uncommon in primary care in the UK with a preponderance among females.

• #16 Ménière’s Disease: Epidemiology | IntechOpen

  https://www.intechopen.com/chapters/56186

  Menieres disease is a disorder of the membranous labyrinth of the inner ear manifesting as vertigo, tinnitus, sensory neural hearing loss and aural fullness of known or unknown origin. The aim of this chapter is to estimate the prevalence of Mnires disease (MD) and its relationship with demographic factors, symptoms and conditions that are known. Few articles have been published on the epidemiology of Menieres disease from 1975 to 1990, studies from Japan indicated a fairly constant prevalence of 17 cases per 100,000 population. […] Kotimaki and colleagues analysed the Finnish population of five million people between 1992 and 1996. A prevalence of 43/100,000 and an average yearly incidence of 4.3/100,000 population were found by the authors. MD is 13 times higher in women than in men and also observed a higher prevalence in adulthood and white people. […] However, in recent years, especially in the last decades, there have been several safe and effective medical and surgical therapies for the treatment of the disease and its sequels.

• #17 Epidemiology of Meniere’s disease

  https://www.dizziness-and-balance.com/disorders/menieres/epidem.html

  In Italy, Celestino and Ralli reported an incidence rate of 8/100,000, and estimated that the prevalence was about 0.4% of the population. […] In Sweden, Stahle et al reported the incidence for 1973 of Meniere’s in Uppsala at 45/100,000 population. […] In Japan there have been several epidemiological studies. According to Watanabe (1988), Meniere’s disease was rare until the 1950’s. Since the end of the second World War, there was a rapid increase in the number of patients designated as having Meniere’s disease. […] There have been several studies of the US population. In the largest study of Harris and Alexander (2010), found about 200/100,000 was the prevalence figure. This matches fairly well with the results of Wladislavosky and associates, who at the Mayo Clinic reported a prevalence in 1980 in the Rochester Minnesota population of 218.2 cases/100,000. They also reported an incidence rate of new cases of 15.3/100,000/year. […] The reported prevalence of bilaterality depends on how one defines bilaterality — as a minor change in hearing in one ear or as having significant impact to either hearing or balance sensation. Estimates vary from as high as 34% (Wladislavosky and associates) in the US, to as low as 5%.

• #18 Epidemiology of Meniere’s disease

  https://www.dizziness-and-balance.com/disorders/menieres/epidem.html

  In Italy, Celestino and Ralli reported an incidence rate of 8/100,000, and estimated that the prevalence was about 0.4% of the population. […] In Sweden, Stahle et al reported the incidence for 1973 of Meniere’s in Uppsala at 45/100,000 population. […] In Japan there have been several epidemiological studies. According to Watanabe (1988), Meniere’s disease was rare until the 1950’s. Since the end of the second World War, there was a rapid increase in the number of patients designated as having Meniere’s disease. […] There have been several studies of the US population. In the largest study of Harris and Alexander (2010), found about 200/100,000 was the prevalence figure. This matches fairly well with the results of Wladislavosky and associates, who at the Mayo Clinic reported a prevalence in 1980 in the Rochester Minnesota population of 218.2 cases/100,000. They also reported an incidence rate of new cases of 15.3/100,000/year. […] The reported prevalence of bilaterality depends on how one defines bilaterality — as a minor change in hearing in one ear or as having significant impact to either hearing or balance sensation. Estimates vary from as high as 34% (Wladislavosky and associates) in the US, to as low as 5%.

• #19 Meniere Disease (Idiopathic Endolymphatic Hydrops): Background, Anatomy, Pathophysiology

  https://emedicine.medscape.com/article/1159069-overview

  In the United States, a prevalence of 1,000 cases of endolymphatic hydrops per 100,000 population is a reasonable approximation, though it is probably an underestimate. Familial predisposition may be a factor, since half of patients have a significant family history. […] The reported prevalence of Mnire disease (ie, idiopathic endolymphatic hydrops) varies widely, from 15 per 100,000 in the United States to 157 per 100,000 in the United Kingdom. […] Bilateral disease is found in 10% of patients with Mnire disease at initial diagnosis; with disease progression, it may be found in more than 40%. […] Mnire disease can be seen at almost all ages: it has been described in children as young as 4 years and in elderly persons older than 90 years. […] The peak incidence of Mnires disease is in the 40- to 60-year-old age group.

• #20 Ménière’s Disease – American Hearing Research Foundation

  https://www.american-hearing.org/disease/menieres-disease/

  Mnires disease (Menieres) is a disorder of the inner ear that sometimes seems to carry with it more questions than answers. In recent years, however, the scientific and medical communitys understanding of Mnires has increased significantly. Although there still is no cure, medical professionals are now better able to advise and treat people with the disorder to help them manage its symptoms. […] Mnires affects roughly 615,000 people in the United States, making it a relatively rare disorder, according to current statistics. About 0.2 percent of the U.S. population has it. And each year about 45,500 new cases are diagnosed. But despite these statistics, there continues to be debate over how common Menieres actually is. […] Although it can come on at any age, most people with Mnires are 40 or older. Onset most often occurs between 40 and 60. And the probability of developing the disorder is fairly equal between both women and men, although some studies do show that women may be more likely to be diagnosed with it.

• #21 Meniere Disease (Idiopathic Endolymphatic Hydrops): Background, Anatomy, Pathophysiology

  https://emedicine.medscape.com/article/1159069-overview

  In the United States, a prevalence of 1,000 cases of endolymphatic hydrops per 100,000 population is a reasonable approximation, though it is probably an underestimate. Familial predisposition may be a factor, since half of patients have a significant family history. […] The reported prevalence of Mnire disease (ie, idiopathic endolymphatic hydrops) varies widely, from 15 per 100,000 in the United States to 157 per 100,000 in the United Kingdom. […] Bilateral disease is found in 10% of patients with Mnire disease at initial diagnosis; with disease progression, it may be found in more than 40%. […] Mnire disease can be seen at almost all ages: it has been described in children as young as 4 years and in elderly persons older than 90 years. […] The peak incidence of Mnires disease is in the 40- to 60-year-old age group.

• #22 Ménière’s Disease: Epidemiology | IntechOpen

  https://www.intechopen.com/chapters/56186

  A study was conducted to estimate the prevalence of Menieres disease in the UK. This study investigated the relationship between some conditions such as mental health, diseases and demographic factors. […] The prevalence of Menires disease was evaluated in the general population of Southern Finland through a prospective study based on population register data. A questionnaire on vertigo associated with a sensation of movement, hearing loss or tinnitus was sent to 5000 people from the age of 12 years randomly selected in the city. […] MD is associated with several comorbid conditions such as arthritis (OR 1.8), psoriasis (OR 1.8), gastroesophageal reflux disease (OR 1.5), irritable bowel syndrome (OR 2.1) and migraine (OR 2.0). […] The prevalence increases dramatically with age, peaking in the 6069 years age group. It is very rare in people younger than 20 years.

• #23 Meniere Disease (Idiopathic Endolymphatic Hydrops): Background, Anatomy, Pathophysiology

  https://emedicine.medscape.com/article/1159069-overview

  Mnire disease appears to be more common in females than in males, with reported ratios ranging from 1.3:1 to 1.8:1. […] The disease primarily affects whites, although this finding too may reflect reporting bias. […] The female predilection of Mnire disease is shared with migraine headache and, in fact, there is a growing body of evidence that Mnire disease and migraine headache may be related and/or different spectrums of the same disease.

• #24 Meniere’s Disease and the Pharmacist

  https://www.uspharmacist.com/article/menieres-disease-and-the-pharmacist

  According to the National Institute on Deafness and Other Communication Disorders (NIDCD), approximately 615,000 adults have been diagnosed with Menieres in the United States, but at least 45,000 to 100,000 new cases are diagnosed each year. However, other authorities quote the prevalence rates in the U.S. to vary from as few as 3.5 patients per 100,000 to as many as 513 per 100,000. […] The onset of Menieres can be felt at any age. However, the primary ages of attack are between 40 and 60 years, and 10% of those aged 65 years or older have Menieres. There is a female-to-male ratio of 1.89:1. Menieres may also occur with more frequency in patients who abuse alcohol or tobacco, are stressed or fatigued, and have allergies.

• #25 Meniere Disease – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK536955/

  The prevalence of Meniere disease varies between 3.5 per 100.000 and 513 per 100.000 and occurs more often in older, white, female patients. […] Several comorbidities have been identified which occur in an increased fashion in patients with Meniere disease: […] Migraine occurs more often in patients diagnosed with Meniere disease, although there is likely significant overlap/misclassification of patients with basilar migraine wrongly diagnosed as having Meniere disease. […] Several autoimmune diseases are associated with Meniere disease, namely rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis. […] Meniere disease is a polygenic disorder. Ten percent of cases in patients of European descent have familial Meniere disease. […] The Brny Society published the current classification of Meniere disease. It is essential to base the diagnosis of Meniere disease on the criteria published and mentioned in this article to warrant a uniform diagnosis, especially in the presence of different international approaches to diagnosing patients with vertigo.

• #26 Ménière’s Disease: Epidemiology | IntechOpen

  https://www.intechopen.com/chapters/56186

  In 1973, Stahle and colleagues reported a prevalence of 46 cases per 100,000 population. From 1975 to 1990, studies from Japan indicated a fairly constant prevalence of 17 cases per 100,000 population. […] Kotimaki and colleagues reported a prevalence of 43/100,000 and an average annual incidence of 4/3,000,000 inhabitants after analysing the Finnish population for a period of 4 years according to the AAOHNS recommendations. […] Estimated prevalence rates range from as low as 3.5 per 100,000 population to as high as 513 per 100,000 population. However, it is clear that Mnires disease is more common in women. […] Most studies suggest a slight female preponderance of up to 1.3 times that of men. MD seems to be much more common in white adults with higher body mass index categories, in their fourth and fifth decade.

• #27 Meniere Disease (Idiopathic Endolymphatic Hydrops): Background, Anatomy, Pathophysiology

  https://emedicine.medscape.com/article/1159069-overview

  In the United States, a prevalence of 1,000 cases of endolymphatic hydrops per 100,000 population is a reasonable approximation, though it is probably an underestimate. Familial predisposition may be a factor, since half of patients have a significant family history. […] The reported prevalence of Mnire disease (ie, idiopathic endolymphatic hydrops) varies widely, from 15 per 100,000 in the United States to 157 per 100,000 in the United Kingdom. […] Bilateral disease is found in 10% of patients with Mnire disease at initial diagnosis; with disease progression, it may be found in more than 40%. […] Mnire disease can be seen at almost all ages: it has been described in children as young as 4 years and in elderly persons older than 90 years. […] The peak incidence of Mnires disease is in the 40- to 60-year-old age group.

• #28 Meniere Disease (Idiopathic Endolymphatic Hydrops): Background, Anatomy, Pathophysiology

  https://emedicine.medscape.com/article/1159069-overview

  In the United States, a prevalence of 1,000 cases of endolymphatic hydrops per 100,000 population is a reasonable approximation, though it is probably an underestimate. Familial predisposition may be a factor, since half of patients have a significant family history. […] The reported prevalence of Mnire disease (ie, idiopathic endolymphatic hydrops) varies widely, from 15 per 100,000 in the United States to 157 per 100,000 in the United Kingdom. […] Bilateral disease is found in 10% of patients with Mnire disease at initial diagnosis; with disease progression, it may be found in more than 40%. […] Mnire disease can be seen at almost all ages: it has been described in children as young as 4 years and in elderly persons older than 90 years. […] The peak incidence of Mnires disease is in the 40- to 60-year-old age group.

• #29 Epidemiology of Meniere’s disease

  https://www.dizziness-and-balance.com/disorders/menieres/epidem.html

  In Italy, Celestino and Ralli reported an incidence rate of 8/100,000, and estimated that the prevalence was about 0.4% of the population. […] In Sweden, Stahle et al reported the incidence for 1973 of Meniere’s in Uppsala at 45/100,000 population. […] In Japan there have been several epidemiological studies. According to Watanabe (1988), Meniere’s disease was rare until the 1950’s. Since the end of the second World War, there was a rapid increase in the number of patients designated as having Meniere’s disease. […] There have been several studies of the US population. In the largest study of Harris and Alexander (2010), found about 200/100,000 was the prevalence figure. This matches fairly well with the results of Wladislavosky and associates, who at the Mayo Clinic reported a prevalence in 1980 in the Rochester Minnesota population of 218.2 cases/100,000. They also reported an incidence rate of new cases of 15.3/100,000/year. […] The reported prevalence of bilaterality depends on how one defines bilaterality — as a minor change in hearing in one ear or as having significant impact to either hearing or balance sensation. Estimates vary from as high as 34% (Wladislavosky and associates) in the US, to as low as 5%.

• #30 An Update on Meniere’s Disease | Canadian Audiologist

  https://canadianaudiologist.ca/an-update-on-menieres-disease/

  The exact incidence of bilateral disease remains unclear but a large population study suggested bilateral disease in about 10 % in the first few years, rising to 40% at 20 years. […] MD continues to vex and challenge physicians and, despite a plethora of publications on the subject, an effective evidence-based treatment or treatment pathway has not been defined. With increasing access to the Internet across the globe, perhaps the time in now ripe to set up worldwide studies involving sufficiently large numbers of patients to answer once and for all which of the current treatments are effective and which are not.

• #31 Meniere Disease – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK536955/

  The prevalence of Meniere disease varies between 3.5 per 100.000 and 513 per 100.000 and occurs more often in older, white, female patients. […] Several comorbidities have been identified which occur in an increased fashion in patients with Meniere disease: […] Migraine occurs more often in patients diagnosed with Meniere disease, although there is likely significant overlap/misclassification of patients with basilar migraine wrongly diagnosed as having Meniere disease. […] Several autoimmune diseases are associated with Meniere disease, namely rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis. […] Meniere disease is a polygenic disorder. Ten percent of cases in patients of European descent have familial Meniere disease. […] The Brny Society published the current classification of Meniere disease. It is essential to base the diagnosis of Meniere disease on the criteria published and mentioned in this article to warrant a uniform diagnosis, especially in the presence of different international approaches to diagnosing patients with vertigo.

• #32

  https://journals.lww.com/10.1097/WCO.0000000000001227

  This review discusses the recent developments on the understanding of epidemiology and genetics of Meniere’s disease. […] Meniere’s disease has been shown to be associated with several comorbidities, such as migraine, anxiety, allergy and immune disorders. Recent studies have investigated the relationship between environmental factors and Meniere’s disease such as air pollution, allergy, asthma, osteoporosis or atmospheric pressure, reporting specific comorbidities in East Asian population. […] While it has attracted emerging attention in recent years, the study of Meniere’s disease genetics is still at its early stage. More geographically and ethnically based human genome studies, and the development of cellular and animal models of Meniere’s disease may help shed light on the molecular mechanisms of Meniere’s disease and provide the potential for gene-specific therapies.

• #33 Meniere Disease – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK536955/

  The prevalence of Meniere disease varies between 3.5 per 100.000 and 513 per 100.000 and occurs more often in older, white, female patients. […] Several comorbidities have been identified which occur in an increased fashion in patients with Meniere disease: […] Migraine occurs more often in patients diagnosed with Meniere disease, although there is likely significant overlap/misclassification of patients with basilar migraine wrongly diagnosed as having Meniere disease. […] Several autoimmune diseases are associated with Meniere disease, namely rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis. […] Meniere disease is a polygenic disorder. Ten percent of cases in patients of European descent have familial Meniere disease. […] The Brny Society published the current classification of Meniere disease. It is essential to base the diagnosis of Meniere disease on the criteria published and mentioned in this article to warrant a uniform diagnosis, especially in the presence of different international approaches to diagnosing patients with vertigo.

• #34 Ménière’s disease – Wikipedia

  https://en.wikipedia.org/wiki/M%C3%A9ni%C3%A8re%27s_disease

  From 3 to 11% of diagnosed dizziness in neuro-otological clinics are due to Mnire’s disease. The annual incidence rate is estimated to be about 15 cases per 100,000 people and the prevalence rate is about 218 per 100,000, and around 15% of people with Mnire’s disease are older than 65. […] In around 9% of cases, a relative also had Mnire’s disease, indicating a genetic predisposition in some cases. […] The odds of Mnire’s disease are greater for people of white ethnicity, with severe obesity, and women. Several conditions are often comorbid with Mnire’s disease, including arthritis, psoriasis, gastroesophageal reflux disease, irritable bowel syndrome, and migraine.

• #35 What is Meniere’s disease / syndrome? | Ménière’s Society

  https://www.menieres.org.uk/information-and-support/symptoms-and-conditions/menieres-disease

  The incidence of Mnire’s is between 1:1000 and 1:2000 of the population; depending on the source. Mnire’s can affect anyone and it can occur at any age. About 7-10% of those affected have a family history of the condition. […] It is widely believed that Mnires develops as a result of an increase in the pressure in the endolymphatic space. The symptoms of ear fullness and reduced hearing are likely to be related to this increase in pressure. The sudden release in pressure accounts for the sudden attacks of vertigo. Repeated episodes of high pressure and sudden releases of that pressure damage the delicate structures of the inner ear and the balance structures of the semi-circular canals. This cumulative damage results in a decline in hearing levels over time.

• #36

  https://journals.lww.com/10.1097/WCO.0000000000001227

  This review discusses the recent developments on the understanding of epidemiology and genetics of Meniere’s disease. […] Meniere’s disease has been shown to be associated with several comorbidities, such as migraine, anxiety, allergy and immune disorders. Recent studies have investigated the relationship between environmental factors and Meniere’s disease such as air pollution, allergy, asthma, osteoporosis or atmospheric pressure, reporting specific comorbidities in East Asian population. […] While it has attracted emerging attention in recent years, the study of Meniere’s disease genetics is still at its early stage. More geographically and ethnically based human genome studies, and the development of cellular and animal models of Meniere’s disease may help shed light on the molecular mechanisms of Meniere’s disease and provide the potential for gene-specific therapies.

• #37 Meniere Disease – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK536955/

  The prevalence of Meniere disease varies between 3.5 per 100.000 and 513 per 100.000 and occurs more often in older, white, female patients. […] Several comorbidities have been identified which occur in an increased fashion in patients with Meniere disease: […] Migraine occurs more often in patients diagnosed with Meniere disease, although there is likely significant overlap/misclassification of patients with basilar migraine wrongly diagnosed as having Meniere disease. […] Several autoimmune diseases are associated with Meniere disease, namely rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis. […] Meniere disease is a polygenic disorder. Ten percent of cases in patients of European descent have familial Meniere disease. […] The Brny Society published the current classification of Meniere disease. It is essential to base the diagnosis of Meniere disease on the criteria published and mentioned in this article to warrant a uniform diagnosis, especially in the presence of different international approaches to diagnosing patients with vertigo.

• #38 Menière’s disease • LITFL • Medical Eponym Library

  https://litfl.com/menieres-disease/

  Age of onset 20-50years. […] Higher incidence of migraine in cases of Menires disease compared to the general population.

• #39 Meniere Disease – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK536955/

  The prevalence of Meniere disease varies between 3.5 per 100.000 and 513 per 100.000 and occurs more often in older, white, female patients. […] Several comorbidities have been identified which occur in an increased fashion in patients with Meniere disease: […] Migraine occurs more often in patients diagnosed with Meniere disease, although there is likely significant overlap/misclassification of patients with basilar migraine wrongly diagnosed as having Meniere disease. […] Several autoimmune diseases are associated with Meniere disease, namely rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis. […] Meniere disease is a polygenic disorder. Ten percent of cases in patients of European descent have familial Meniere disease. […] The Brny Society published the current classification of Meniere disease. It is essential to base the diagnosis of Meniere disease on the criteria published and mentioned in this article to warrant a uniform diagnosis, especially in the presence of different international approaches to diagnosing patients with vertigo.

• #40 Meniere Disease (Idiopathic Endolymphatic Hydrops): Background, Anatomy, Pathophysiology

  https://emedicine.medscape.com/article/1159069-overview

  Mnire disease appears to be more common in females than in males, with reported ratios ranging from 1.3:1 to 1.8:1. […] The disease primarily affects whites, although this finding too may reflect reporting bias. […] The female predilection of Mnire disease is shared with migraine headache and, in fact, there is a growing body of evidence that Mnire disease and migraine headache may be related and/or different spectrums of the same disease.

• #41 Meniere Disease – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK536955/

  The prevalence of Meniere disease varies between 3.5 per 100.000 and 513 per 100.000 and occurs more often in older, white, female patients. […] Several comorbidities have been identified which occur in an increased fashion in patients with Meniere disease: […] Migraine occurs more often in patients diagnosed with Meniere disease, although there is likely significant overlap/misclassification of patients with basilar migraine wrongly diagnosed as having Meniere disease. […] Several autoimmune diseases are associated with Meniere disease, namely rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis. […] Meniere disease is a polygenic disorder. Ten percent of cases in patients of European descent have familial Meniere disease. […] The Brny Society published the current classification of Meniere disease. It is essential to base the diagnosis of Meniere disease on the criteria published and mentioned in this article to warrant a uniform diagnosis, especially in the presence of different international approaches to diagnosing patients with vertigo.

• #42 Population-based study for the comorbidities and associated factors in Ménière’s disease | Scientific Reports

  https://www.nature.com/articles/s41598-022-12492-y

  Moreover, no significant differences in the incidence of autoimmune diseases and cerebro- and cardiovascular disease were observed between patients with MD and controls. […] The association between autoimmunity and MD has been supported by the high prevalence of systemic autoimmune diseases in patients with MD. […] The relationship between metabolic disorder and MD has also been suggested. […] Therefore, the present study results are not consistent with those of previous studies. […] In conclusion, this study observed the comorbidities and conditions of patients with MD using a national population database, multiple diagnostic criteria, and stratified matched control group. […] To the best of our knowledge, this study is the first globally to observe objective laboratory findings and to compare height, weight, BMI, waist circumference, BP, and many comorbidities using population-based design in Asian countries. […] Some of the results are not consistent with those of previous studies; therefore, other well-designed studies for other races will be needed to generalize the results of this study.

• #43

  https://link.springer.com/article/10.1007/s10238-023-01192-0

  The etiology of Mnires disease (MD) remains controversial. […] Previous reviews have mainly focused on clinical epidemiology studies of patients. […] Patients with MD tend to have a high risk of comorbid allergies or an allergy history, showing positive allergy immunology characteristics. […] Other MD-related diseases, such as migraine, may also interact with allergies. […] Allergy mediators such as IgE may worsen the symptoms of MD. […] Anti-allergy therapy plays a positive role in patients with MD and animal models of endolymphatic hydrops. […] Current epidemiology of Menieres syndrome. […] Prevalence of Menires disease in general population of Southern Finland. […] Prevalence, associated factors, and comorbid conditions for Mnires disease. […] High prevalence of systemic autoimmune diseases in patients with Menires disease. […] Prevalence of allergy in Menires disease. […] Co-morbidity of migraine and Mnires disease: is allergy the link? […] Population-based study on the epidemiology of Mnires disease.

• #44 Population-based study for the comorbidities and associated factors in Ménière’s disease | Scientific Reports

  https://www.nature.com/articles/s41598-022-12492-y

  To date, no study has reported the objective metabolic laboratory findings worldwide or the comorbidities for Mnires disease (MD) using a population-based design in Asian populations. […] The aim of this study was to investigate the comorbidities and associated factors for MD using the Korean National Health Insurance Service database. […] In recent population-based studies, the incidence of MD was 13118 per 100,000 persons. […] However, the majority of studies are limited by a lack of population-based cohorts and low number of cases; therefore, the underlying disease pathological pathways remain unclear. […] Furthermore, despite the recent rapid increase in the incidence of MD in Asian populations, few studies have reported the comorbidities of MD in Asian countries. […] We found an increase in the incidence of allergic rhinitis and allergic asthma in patients with MD, similar to that in previous studies that reported a higher number of patients with a history of allergy and the prevalence of allergic diseases.

• #45 Meniere’s Disease: Update | Dr Sean Flanagan

  https://sydneyentclinic.com/sean-flanagan/patient-resources-2/menieres-disease/

  Allergies are up to three times as prevalent in Menieres Disease. […] The commonest drug used is Betahistine (Serc). […] Diuretic therapy, (fluid tablets) have been used for many years in Menieres. […] Intervention in Menieres disease is divided into non-destructive and destructive categories. […] Intratympanic steroid therapy has now become the initial interventional non-ablative treatment option. […] Tympanostomy tube insertion (grommets) can be placed and are thought to influence inner ear pressure by stabilizing middle ear pressure, and perhaps the degree of inner ear instability. […] Endolymphatic sac surgery involves a mastoidectomy and opening of the endolymphatic sac which in theory stabilizes inner ear homeostasis. […] Intratympanic gentamicin has significantly changed interventional management in Menieres disease over the last 20 years.

• #46

  https://link.springer.com/article/10.1007/s10238-023-01192-0

  The etiology of Mnires disease (MD) remains controversial. […] Previous reviews have mainly focused on clinical epidemiology studies of patients. […] Patients with MD tend to have a high risk of comorbid allergies or an allergy history, showing positive allergy immunology characteristics. […] Other MD-related diseases, such as migraine, may also interact with allergies. […] Allergy mediators such as IgE may worsen the symptoms of MD. […] Anti-allergy therapy plays a positive role in patients with MD and animal models of endolymphatic hydrops. […] Current epidemiology of Menieres syndrome. […] Prevalence of Menires disease in general population of Southern Finland. […] Prevalence, associated factors, and comorbid conditions for Mnires disease. […] High prevalence of systemic autoimmune diseases in patients with Menires disease. […] Prevalence of allergy in Menires disease. […] Co-morbidity of migraine and Mnires disease: is allergy the link? […] Population-based study on the epidemiology of Mnires disease.

• #47 Ménière’s Disease: Epidemiology | IntechOpen

  https://www.intechopen.com/chapters/56186

  A study was conducted to estimate the prevalence of Menieres disease in the UK. This study investigated the relationship between some conditions such as mental health, diseases and demographic factors. […] The prevalence of Menires disease was evaluated in the general population of Southern Finland through a prospective study based on population register data. A questionnaire on vertigo associated with a sensation of movement, hearing loss or tinnitus was sent to 5000 people from the age of 12 years randomly selected in the city. […] MD is associated with several comorbid conditions such as arthritis (OR 1.8), psoriasis (OR 1.8), gastroesophageal reflux disease (OR 1.5), irritable bowel syndrome (OR 2.1) and migraine (OR 2.0). […] The prevalence increases dramatically with age, peaking in the 6069 years age group. It is very rare in people younger than 20 years.

• #48 Ménière’s disease – Wikipedia

  https://en.wikipedia.org/wiki/M%C3%A9ni%C3%A8re%27s_disease

  From 3 to 11% of diagnosed dizziness in neuro-otological clinics are due to Mnire’s disease. The annual incidence rate is estimated to be about 15 cases per 100,000 people and the prevalence rate is about 218 per 100,000, and around 15% of people with Mnire’s disease are older than 65. […] In around 9% of cases, a relative also had Mnire’s disease, indicating a genetic predisposition in some cases. […] The odds of Mnire’s disease are greater for people of white ethnicity, with severe obesity, and women. Several conditions are often comorbid with Mnire’s disease, including arthritis, psoriasis, gastroesophageal reflux disease, irritable bowel syndrome, and migraine.

• #49

  https://journals.lww.com/10.1097/WCO.0000000000001227

  This review discusses the recent developments on the understanding of epidemiology and genetics of Meniere’s disease. […] Meniere’s disease has been shown to be associated with several comorbidities, such as migraine, anxiety, allergy and immune disorders. Recent studies have investigated the relationship between environmental factors and Meniere’s disease such as air pollution, allergy, asthma, osteoporosis or atmospheric pressure, reporting specific comorbidities in East Asian population. […] While it has attracted emerging attention in recent years, the study of Meniere’s disease genetics is still at its early stage. More geographically and ethnically based human genome studies, and the development of cellular and animal models of Meniere’s disease may help shed light on the molecular mechanisms of Meniere’s disease and provide the potential for gene-specific therapies.

• #50 Association between Meniere’s disease and air pollution in South Korea | Scientific Reports

  https://www.nature.com/articles/s41598-021-92355-0

  Menieres disease is thought to be a disorder of the inner ear function, affected by genetic and environmental factors. […] The purpose of this study was to investigate the relationship between the Menieres disease occurrence and air pollution status in Korea. […] In total, 29,646 (32.1% males and 67.9% females) Menieres disease cases were identified from Korea NHIS-NSC database between 2008 and 2015. […] Overall, SO2, NO2, CO, and PM10 showed significant correlation with Menieres disease risk at immediate lags, and weaker correlation at delayed lags, whereas O3 showed slightly negative correlation at the immediate lag (lag0) and PM2.5 did not show strong correlation. […] Our results showed that hospital visits for Menieres disease were associated with the measured concentrations of ambient air pollutants SO2, NO2, CO, and PM10.

• #51 Association between Meniere’s disease and air pollution in South Korea | Scientific Reports

  https://www.nature.com/articles/s41598-021-92355-0

  Our time-stratified case-crossover analysis showed that Menieres disease hospital visits were associated with the measured concentrations of ambient air pollutants such as SO2, NO2, CO, and PM10. This association was stronger in the age of 4064, female, summer (JuneAugust) season, and urban subgroups. Further studies are needed to confirm these associations and determine their mechanisms.

• #52 Ménière’s Disease – American Hearing Research Foundation

  https://www.american-hearing.org/disease/menieres-disease/

  Medically, Mnires is sometimes referred to as idiopathic (or primary) endolymphatic hydrops. The idiopathic label means that it arises for no known reason. Its important to understand that elevated endolymphatic pressure isnt unique to Mnires and can be caused by a number of other conditionshead trauma or diabetes, for instance. When caused by other conditions, however, its typically called secondary endolymphatic hydrops. […] Diagnosing Mnires is difficult because the symptoms overlap with many other diseases and conditions. For example, dizziness and imbalance can be a symptom of anything from dehydration to hormonal imbalances, to tumorsin rare cases. So, its important to see a medical professional who specializes in ear disorderswith Mnires experience, whenever possible. This may help to minimize the time it takes to determine if the symptoms are attributable to Mnires or to something entirely different.

• #53 Meniere Disease – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK536955/

  The prevalence of Meniere disease varies between 3.5 per 100.000 and 513 per 100.000 and occurs more often in older, white, female patients. […] Several comorbidities have been identified which occur in an increased fashion in patients with Meniere disease: […] Migraine occurs more often in patients diagnosed with Meniere disease, although there is likely significant overlap/misclassification of patients with basilar migraine wrongly diagnosed as having Meniere disease. […] Several autoimmune diseases are associated with Meniere disease, namely rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis. […] Meniere disease is a polygenic disorder. Ten percent of cases in patients of European descent have familial Meniere disease. […] The Brny Society published the current classification of Meniere disease. It is essential to base the diagnosis of Meniere disease on the criteria published and mentioned in this article to warrant a uniform diagnosis, especially in the presence of different international approaches to diagnosing patients with vertigo.

• #54 #379 Hearing Loss, Tinnitus, and Meniere’s Disease – The Curbsiders

  https://thecurbsiders.com/curbsiders-podcast/379-hearing-loss-tinnitus-and-menieres-disease

  Meniere’s disease is uncommon. Consider vestibular migraine as a more common cause for dizziness. […] Patients with Meniere’s disease are recommended to balance sodium intake throughout the day, avoiding large variations to minimize symptoms. […] A clinical diagnosis of Meniere’s Disease is made based upon the following criteria: Two or more spontaneous episodes of vertigo, each lasting 20 minutes to 12 hours; Audiometrically documented low- to mid-frequency sensorineural hearing loss in the affected ear; Fluctuating aural symptoms (reduced or distorted hearing, tinnitus, or fullness) in the affected ear; Other differentials have been excluded. […] Around 25% of Meniere’s disease patients will develop bilateral symptoms, but it typically occurs sequentially, not concurrently. […] Dr Rauch recommends a patient-centered, conservative approach, controlling their symptoms with minimum intervention if possible. Patients should be counseled on the following: Diet and establishing a regular schedule should be first line treatments, including minimizing stress, improving sleep, and regular mealtimes. Dietary salt intake should be balanced throughout the day, avoiding large variation. Replace fluid and electrolytes before and during exercise. For those few patients that have severe symptoms other treatments are available, such as gentamicin (or methylprednisolone) intratympanic infusion. Diuretics are commonly used to reduce vertigo crises, but the evidence is not strong.

• #55

  https://www.ijorl.com/index.php/ijorl/article/view/3498/0

  The probable MD is a broader concept defined by episodic vertigo associated with fluctuating aural symptoms lasting for 20 min to 24 hours. […] Current epidemiology of Menieres syndrome. […] Epidemiology and seasonal variation of Mnires disease: Data from a population-based study. […] Menieres disease: prevalence of contralateral ear involvement. […] Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Meniere’s disease. […] Systematic review of magnetic resonance imaging for diagnosis of Meniere disease.

• #56 An Update on Meniere’s Disease | Canadian Audiologist

  https://canadianaudiologist.ca/an-update-on-menieres-disease/

  In 1861, the French physician Prosper Meniere described a syndrome characterised by the presence of intermittent vertigo, tinnitus and hearing loss, correctly proposing that the site of the pathology was the inner ear. Subsequently, the condition was correlated histopathologically with the presence of endolymphatic hydrous although the etiology remains unclear and as yet there is no definitive diagnostic test. Where Menieres symptoms arise due to a recognised cause, such as syphilis or Cogans syndrome, the term Menieres syndrome is used, whilst the term Menieres disease (MD) is applied if there is no identifiable cause. At the present time, Menieres disease is a committee diagnosis one whose diagnosis relies on fulfilling criteria agreed upon by a panel of experts. The most recent guidelines were published by the American Academy of Otolaryngology Committee on Hearing and Equilibrium in 1995.

• #57 An Update on the Epidemiology and Clinicodemographic Features of Meniere’s Disease – PubMed

  https://pubmed.ncbi.nlm.nih.gov/38238895/

  Objective: To characterize the estimated prevalence and clinicodemographic features of Meniere’s disease (MD) using current diagnostic criteria. […] Of 806 ICD-10 diagnoses of MD, we identified 480 MD cases meeting diagnostic criteria (168 definite). […] Among MD diagnoses, there is a low estimated prevalence of MD meeting diagnostic criteria, and an even lower prevalence of definite MD.

• #58 An Update on the Epidemiology and Clinicodemographic Features of Meniere’s Disease – PubMed

  https://pubmed.ncbi.nlm.nih.gov/38238895/

  Objective: To characterize the estimated prevalence and clinicodemographic features of Meniere’s disease (MD) using current diagnostic criteria. […] Of 806 ICD-10 diagnoses of MD, we identified 480 MD cases meeting diagnostic criteria (168 definite). […] Among MD diagnoses, there is a low estimated prevalence of MD meeting diagnostic criteria, and an even lower prevalence of definite MD.

• #59 Meniere Disease p. 1. Diagnosis criteria, signs and sy…

  https://otorhinolaryngologypl.com/seo/article/01.3001.0013.2050/en

  Similar to the previously published studies, in our group the vertigo spells accompanied by falls with no loss of consciousness tended to become more frequent as the disease progressed. […] The 2016 diagnostic criteria also include delayed Ménierè’s disease. This is the case when the auditory symptoms precede vertigo attacks by months or years, or vertigo spells precede hearing loss by weeks or months. […] Another attempt to classify MD based on epidemiological studies was made by the European Ménierè’s Disease Consortium, a European multicenter initiative to collect data on patients with this disease. They distinguished five subtypes of MD in patients with uni- or bilateral disease.

• #60 Diagnostic assessment of patients with Meniere’s disease through caloric testing and the video-head-impulse test | Brazilian Journal of Otorhinolaryngology

  https://www.elsevier.es/en-revista-brazilian-journal-otorhinolaryngology-english-edition–497-articulo-diagnostic-assessment-patients-with-meniere39s-S1808869419301417

  Meniere’s disease is a labyrinth disease that usually presents with episodes of spontaneous vertigo associated with sensorineural hearing loss, tinnitus and ipsi- and unilateral aural fullness in most cases. […] Although there are no specific findings for the diagnosis of MD in vestibular tests, functional assessment of inner ear structures is important to measure disease impairment, in order to establish prognosis and more specific treatment. […] The caloric test (CT) is the oldest method for functional assessment of the vestibular system, although it only evaluates the lateral semicircular canals (SCCs), through low frequency stimuli, around 0.0020.004Hz, allowing the separate identification of the impaired labyrinth. […] Despite the several scientific studies carried out on MD, it is not yet clear how vestibular function is influenced by this disease.

• #61 SciELO Brazil – Diagnostic assessment of patients with Meniere’s disease through caloric testing and the video-head-impulse test Diagnostic assessment of patients with Meniere’s disease through caloric testing and the video-head-impulse test

  https://www.scielo.br/j/bjorl/a/r994m5tjhQMNMwVmmpsWXXg/

  Most patients with definite Meniere’s disease showed hyporeflexia at the caloric test and video-head-impulse test with normal function in the symptomatic ear. […] The prevalence of hyporeflexia at the caloric test was higher in symptomatic (56.4%) and asymptomatic (36%) ears of patients with Meniere’s disease compared to the ears of control subjects (7.5%), p0.001 and p = 0.004, respectively. […] The video-head-impulse test showed more alterations in the lateral semicircular canals. […] Absolute or relative hyporeflexia was more frequent in symptomatic and asymptomatic ears of patients with definite MD when compared to controls. […] The frequency of alterations in the vHIT, when considering the decreased gain and presence of covert and/or overt saccades, was more frequent in the lateral SCCs in symptomatic ears when compared to the control group, with a statistically significant difference.

• #62 Diagnostic assessment of patients with Meniere’s disease through caloric testing and the video-head-impulse test | Brazilian Journal of Otorhinolaryngology

  https://www.elsevier.es/en-revista-brazilian-journal-otorhinolaryngology-english-edition–497-articulo-diagnostic-assessment-patients-with-meniere39s-S1808869419301417

  The aim of this study was to describe the results obtained at the CT and vHIT in patients with definite MD and to compare the results obtained between symptomatic and asymptomatic ears of patients with MD and also with those of the control group. […] The prevalence of hyporeflexia in the symptomatic ear was in agreement with Proctor. […] The current sample also showed a prevalence of 36% of hyporeflexia in asymptomatic ears, which differs from that found by this author, in which only 19% of patients with unilateral MD had hyporeflexia in the asymptomatic side. […] This research confirms the need for the evaluation of both ears, even in cases of unilateral disease, showing that functional impairment may be present before the clinical manifestation of symptoms.

• #63 Top Published Expert Doctors for Meniere Disease

  https://www.findexpertmd.com/d/Meniere_Disease?physician=physician

  404 top medical experts on Meniere Disease across 29 countries and 28 U.S. states, including 301 MDs (Physicians). This is based on an objective analysis of their Scientific Publications, Clinical Trials, Medicare, and NIH Grants. […] Clinical Trials ClinicalTrials.gov : at least 56 including 24 Completed, 12 Recruiting.

• #64 Top Published Expert Doctors for Meniere Disease

  https://findexpertmd.com/d/Meniere_Disease

  404 top medical experts on Meniere Disease across 29 countries and 28 U.S. states, including 301 MDs (Physicians). This is based on an objective analysis of their Scientific Publications, Clinical Trials, Medicare, and NIH Grants. […] Clinical Trials ClinicalTrials.gov: at least 56 including 24 Completed, 12 Recruiting.

• #65 Meniere Disease p. 1. Diagnosis criteria, signs and sy…

  https://otorhinolaryngologypl.com/seo/article/01.3001.0013.2050/en

  Similar to the previously published studies, in our group the vertigo spells accompanied by falls with no loss of consciousness tended to become more frequent as the disease progressed. […] The 2016 diagnostic criteria also include delayed Ménierè’s disease. This is the case when the auditory symptoms precede vertigo attacks by months or years, or vertigo spells precede hearing loss by weeks or months. […] Another attempt to classify MD based on epidemiological studies was made by the European Ménierè’s Disease Consortium, a European multicenter initiative to collect data on patients with this disease. They distinguished five subtypes of MD in patients with uni- or bilateral disease.

• #66 Ménière’s Disease – American Hearing Research Foundation

  https://www.american-hearing.org/disease/menieres-disease/

  The Mnires Disease Symposium sponsored by the American Hearing Research Foundation and Hearing Health Foundation was held on Friday, February 21, 2025, the Friday before the 48th Annual ARO MidWinter Meeting in Orlando hosted by the Association for Research in Otolaryngology (ARO). The symposium brought together researchers and clinicians to collaborate, share ideas, and spark new projects aimed at better understanding and treating Mnires diseasea chronic inner ear condition that affects balance and hearing. AHRF, HHF, and their partners are dedicated to supporting research that improves the lives of the hundreds of thousands of people living with this condition worldwide.

• #67 Current Epidemiology of Meniere’s Syndrome – EM consulte

  https://www.em-consulte.com/article/316172/current-epidemiology-of-menieres-syndrome

  The burden of Mnire syndrome (MS) is substantial, especially when considering the significant impact on the quality of life of those affected. Reported estimates of incidence and prevalence have varied widely due to methodological differences between studies, changes in criteria for diagnosis of MS, and differences in populations studied. Reported prevalence rates for MS range from 3.5 per 100,000 to 513 per 100,000. A recent study using health claims data for more than 60 million patients in the United States found prevalence of 190 per 100,000 with a female:male ratio of 1.89:1. The prevalence of MS increases with increasing age. […] Keywords : Menieres syndrome, Prevalence, Epidemiology, Incidence

• #68 Pharmacologic and surgical therapies for patients with Meniere’s disease: A systematic review and network meta-analysis | PLOS One

  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0237523

  Menieres disease (MD) is a chronic condition of the inner ear consisting of symptoms that include vertigo attacks, fluctuating sensorineural hearing loss, tinnitus and aural fullness. […] Despite the availability of various interventions, there is uncertainty surrounding their comparative efficacy, making it difficult to select the appropriate treatment. We conducted a systematic review incorporating pairwise and network meta-analyses (NMAs) with the objectives to assess the relative effects of the available pharmacologic and surgical interventions in patients with MD with regard to vertigo and other key outcomes. […] Early detection of MD and rapid intervention are important to reduce the damaging effects of MD on patients quality of life. […] The objective of this systematic review was to assess the relative effects of the available pharmacologic and surgical interventions in patients with MD with regard to vertigo and other key patient outcomes based on data from randomized clinical trials (RCTs).

• #69 Meniere disease: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000702.htm

  Ménière disease is a fairly common disorder. […] Ménière disease can often be controlled with treatment. Or, the condition may get better on its own. In some cases, Ménière disease can be chronic (long-term) or disabling. […] You can’t prevent Ménière disease. Treating early symptoms right away may help prevent the condition from getting worse. Treating an ear infection and other related disorders may be helpful.

• #70 Meniere’s Disease: Update | Dr Sean Flanagan

  https://sydneyentclinic.com/sean-flanagan/patient-resources-2/menieres-disease/

  A disorder affecting inner ear homeostasis, classically manifested by episodic vertigo lasting hours, fluctuating hearing loss, tinnitus and aural fullness. The reported prevalence varies widely but probably sits around 190 per 100,000. It is almost twice as common in women than men, and most commonly presents in the age range from 20-60 years. Whilst usually affecting only one ear, approximately 15% of cases will involve both ears. […] The overwhelming goal of long term management is to minimise the number of vertigo attacks and maintain hearing and balance function, and in the acute phase to truncate the severity of an attack. […] Approximately 75-80% of patients can achieve good control with non-interventional treatment. […] Management of stress and ensuring adequate sleep is essential.

• #71 #379 Hearing Loss, Tinnitus, and Meniere’s Disease – The Curbsiders

  https://thecurbsiders.com/curbsiders-podcast/379-hearing-loss-tinnitus-and-menieres-disease

  Meniere’s disease is uncommon. Consider vestibular migraine as a more common cause for dizziness. […] Patients with Meniere’s disease are recommended to balance sodium intake throughout the day, avoiding large variations to minimize symptoms. […] A clinical diagnosis of Meniere’s Disease is made based upon the following criteria: Two or more spontaneous episodes of vertigo, each lasting 20 minutes to 12 hours; Audiometrically documented low- to mid-frequency sensorineural hearing loss in the affected ear; Fluctuating aural symptoms (reduced or distorted hearing, tinnitus, or fullness) in the affected ear; Other differentials have been excluded. […] Around 25% of Meniere’s disease patients will develop bilateral symptoms, but it typically occurs sequentially, not concurrently. […] Dr Rauch recommends a patient-centered, conservative approach, controlling their symptoms with minimum intervention if possible. Patients should be counseled on the following: Diet and establishing a regular schedule should be first line treatments, including minimizing stress, improving sleep, and regular mealtimes. Dietary salt intake should be balanced throughout the day, avoiding large variation. Replace fluid and electrolytes before and during exercise. For those few patients that have severe symptoms other treatments are available, such as gentamicin (or methylprednisolone) intratympanic infusion. Diuretics are commonly used to reduce vertigo crises, but the evidence is not strong.

• #72 #379 Hearing Loss, Tinnitus, and Meniere’s Disease – The Curbsiders

  https://thecurbsiders.com/curbsiders-podcast/379-hearing-loss-tinnitus-and-menieres-disease

  Meniere’s disease is uncommon. Consider vestibular migraine as a more common cause for dizziness. […] Patients with Meniere’s disease are recommended to balance sodium intake throughout the day, avoiding large variations to minimize symptoms. […] A clinical diagnosis of Meniere’s Disease is made based upon the following criteria: Two or more spontaneous episodes of vertigo, each lasting 20 minutes to 12 hours; Audiometrically documented low- to mid-frequency sensorineural hearing loss in the affected ear; Fluctuating aural symptoms (reduced or distorted hearing, tinnitus, or fullness) in the affected ear; Other differentials have been excluded. […] Around 25% of Meniere’s disease patients will develop bilateral symptoms, but it typically occurs sequentially, not concurrently. […] Dr Rauch recommends a patient-centered, conservative approach, controlling their symptoms with minimum intervention if possible. Patients should be counseled on the following: Diet and establishing a regular schedule should be first line treatments, including minimizing stress, improving sleep, and regular mealtimes. Dietary salt intake should be balanced throughout the day, avoiding large variation. Replace fluid and electrolytes before and during exercise. For those few patients that have severe symptoms other treatments are available, such as gentamicin (or methylprednisolone) intratympanic infusion. Diuretics are commonly used to reduce vertigo crises, but the evidence is not strong.

• #73 An Update on Meniere’s Disease | Canadian Audiologist

  https://canadianaudiologist.ca/an-update-on-menieres-disease/

  The exact incidence of bilateral disease remains unclear but a large population study suggested bilateral disease in about 10 % in the first few years, rising to 40% at 20 years. […] MD continues to vex and challenge physicians and, despite a plethora of publications on the subject, an effective evidence-based treatment or treatment pathway has not been defined. With increasing access to the Internet across the globe, perhaps the time in now ripe to set up worldwide studies involving sufficiently large numbers of patients to answer once and for all which of the current treatments are effective and which are not.

• #74 An Update on Meniere’s Disease | Canadian Audiologist

  https://canadianaudiologist.ca/an-update-on-menieres-disease/

  The exact incidence of bilateral disease remains unclear but a large population study suggested bilateral disease in about 10 % in the first few years, rising to 40% at 20 years. […] MD continues to vex and challenge physicians and, despite a plethora of publications on the subject, an effective evidence-based treatment or treatment pathway has not been defined. With increasing access to the Internet across the globe, perhaps the time in now ripe to set up worldwide studies involving sufficiently large numbers of patients to answer once and for all which of the current treatments are effective and which are not.

• #75 Association between Meniere’s disease and air pollution in South Korea | Scientific Reports

  https://www.nature.com/articles/s41598-021-92355-0

  Our time-stratified case-crossover analysis showed that Menieres disease hospital visits were associated with the measured concentrations of ambient air pollutants such as SO2, NO2, CO, and PM10. This association was stronger in the age of 4064, female, summer (JuneAugust) season, and urban subgroups. Further studies are needed to confirm these associations and determine their mechanisms.

• #76 Population-based study for the comorbidities and associated factors in Ménière’s disease | Scientific Reports

  https://www.nature.com/articles/s41598-022-12492-y

  Moreover, no significant differences in the incidence of autoimmune diseases and cerebro- and cardiovascular disease were observed between patients with MD and controls. […] The association between autoimmunity and MD has been supported by the high prevalence of systemic autoimmune diseases in patients with MD. […] The relationship between metabolic disorder and MD has also been suggested. […] Therefore, the present study results are not consistent with those of previous studies. […] In conclusion, this study observed the comorbidities and conditions of patients with MD using a national population database, multiple diagnostic criteria, and stratified matched control group. […] To the best of our knowledge, this study is the first globally to observe objective laboratory findings and to compare height, weight, BMI, waist circumference, BP, and many comorbidities using population-based design in Asian countries. […] Some of the results are not consistent with those of previous studies; therefore, other well-designed studies for other races will be needed to generalize the results of this study.

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