Materiały źródłowe

• #1 Idiopathic Intracranial Hypertension: Prognostic Factors and Multidisciplinary Management

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5572623/

  Idiopathic intracranial hypertension (IIH) mostly affects young obese women and can lead to permanent visual impairment. However, prognostic factors and therapeutic strategy remain unclear. […] Weight gain, rather than initial weight, emerged as the leading factor of poor visual outcome in patients with IIH, followed by presence of bilateral TSS. […] Our results indicate that the first reason for poor IIH prognosis is weight gain followed by bilateral TSS. […] In patients with IIH, weight gain, as opposed to initial BMI, is the leading factor of poor visual outcome. Other identified criteria, but to a lesser extent, are bilateral TSS in the overall population and older age in patients with bilateral TSS only. This emphasizes cross-links between weight gain and high cerebral venous pressure in the pathogenesis of IIH. Unilateral TSS stenting appears to be a safe and effective treatment to overcome this pathological circle in patients with bilateral TSS but should be reserved only after measures are undertaken to achieve weight loss.

• #2 Idiopathic intracranial hypertension (pseudotumor cerebri): Prognosis and treatment – UpToDate

  https://www.uptodate.com/contents/idiopathic-intracranial-hypertension-pseudotumor-cerebri-prognosis-and-treatment

  Idiopathic intracranial hypertension (IIH) was formerly called pseudotumor cerebri. It is a disorder defined by clinical criteria that include symptoms and signs isolated to those produced by increased intracranial pressure (ICP; eg, headache, papilledema, double vision, transient visual obscurations, and vision loss), elevated ICP with normal cerebrospinal fluid (CSF) composition, and no other cause of intracranial hypertension evident on neuroimaging or other evaluations. […] Many patients suffer from intractable, disabling headaches, and there is a risk of severe, permanent vision loss in approximately 5 to 15 percent of patients. […] The natural history of IIH is variable, with some patients resolving within months, while in others, the condition is chronic or recurrent. […] The major morbidity associated with idiopathic intracranial hypertension (IIH) is vision loss. As much as 15 percent of individuals with IIH may be at risk of severe, permanent vision loss.

• #3 Idiopathic intracranial hypertension (pseudotumor cerebri): Prognosis and treatment – UpToDate

  https://www.uptodate.com/contents/idiopathic-intracranial-hypertension-pseudotumor-cerebri-prognosis-and-treatment

  Permanent disabling vision loss is the major morbidity associated with IIH but is uncommon. While an early, hospital-based study found that 24 percent of 57 patients developed blindness or severe visual impairment, subsequent studies that have been outpatient based have found a lower rate of severe visual loss of 6 to 14 percent. […] A recurrence of symptoms may occur in 8 to 38 percent of patients after recovery from an episode of IIH or after a prolonged period of stability. Weight gain is a common but not universal antecedent to recurrent IIH. […] Most patients with IIH improve or stabilize with medical treatment over the course of several months. Recurrences may occur even after several years, necessitating ongoing monitoring.

• #4 Idiopathic Intracranial Hypertension: Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/21968-idiopathic-intracranial-hypertension

  IIH is rare. It affects an estimated .2 to 2 people (between ages 25 and 36) out of 100,000 in a general population study. […] IIH isn’t life-threatening. However, symptoms can cause permanent vision changes that can affect your quality of life. A healthcare provider can quickly treat this condition to prevent complications. […] IIH may lead to vision loss if untreated. This is irreversible. A healthcare provider can offer treatment options to prevent this complication, so let them know as soon as possible if you notice changes to your vision. […] The goals of IIH treatment are to decrease pressure on your brain and prevent vision loss. […] Timely treatment at the first sign of vision changes or symptoms can help reduce your risk of complications like permanent vision loss. Treatment is often successful at relieving symptoms. Your healthcare provider can give you the best information on what you can expect in your situation. […] IIH doesn’t directly affect your life expectancy. Most people have a normal life expectancy. […] There isn’t a cure for IIH, so you may have to manage this condition for the rest of your life.

• #5 Idiopathic Intracranial Hypertension (IIH): Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1214410-overview

  Idiopathic intracranial hypertenion (IIH) is not known to be associated with any specific mortality risk, but endovascular and surgical treatments (eg, venous sinus stenting or shunting) may cause morbidity and mortality. The increased mortality associated with morbid obesity has a selective expression in this group because of the strong predilection of the disease to affect obese females. […] The morbidity of IIH mainly is related to the effects of papilledema on visual function. If left untreated, long-standing disc edema results in an irreversible optic neuropathy with accompanying constriction of the visual field and loss of color vision. In end-stage papilledema, central visual acuity also is involved. With timely and appropriate treatment of IIH, the visual prognosis can be encouraging.

• #6 Idiopathic intracranial hypertension (pseudotumor cerebri): Prognosis and treatment – UpToDate

  https://www.uptodate.com/contents/idiopathic-intracranial-hypertension-pseudotumor-cerebri-prognosis-and-treatment

  Idiopathic intracranial hypertension (IIH) was formerly called pseudotumor cerebri. It is a disorder defined by clinical criteria that include symptoms and signs isolated to those produced by increased intracranial pressure (ICP; eg, headache, papilledema, double vision, transient visual obscurations, and vision loss), elevated ICP with normal cerebrospinal fluid (CSF) composition, and no other cause of intracranial hypertension evident on neuroimaging or other evaluations. […] Many patients suffer from intractable, disabling headaches, and there is a risk of severe, permanent vision loss in approximately 5 to 15 percent of patients. […] The natural history of IIH is variable, with some patients resolving within months, while in others, the condition is chronic or recurrent. […] The major morbidity associated with idiopathic intracranial hypertension (IIH) is vision loss. As much as 15 percent of individuals with IIH may be at risk of severe, permanent vision loss.

• #7 Idiopathic intracranial hypertension (pseudotumor cerebri): Prognosis and treatment – UpToDate

  https://www.uptodate.com/contents/idiopathic-intracranial-hypertension-pseudotumor-cerebri-prognosis-and-treatment

  Permanent disabling vision loss is the major morbidity associated with IIH but is uncommon. While an early, hospital-based study found that 24 percent of 57 patients developed blindness or severe visual impairment, subsequent studies that have been outpatient based have found a lower rate of severe visual loss of 6 to 14 percent. […] A recurrence of symptoms may occur in 8 to 38 percent of patients after recovery from an episode of IIH or after a prolonged period of stability. Weight gain is a common but not universal antecedent to recurrent IIH. […] Most patients with IIH improve or stabilize with medical treatment over the course of several months. Recurrences may occur even after several years, necessitating ongoing monitoring.

• #8 Idiopathic intracranial hypertension – Wikipedia

  https://en.wikipedia.org/wiki/Idiopathic_intracranial_hypertension

  Prognosis Variable[2] […] It is not known what percentage of people with IIH will remit spontaneously, and what percentage will develop chronic disease.[9] […] IIH does not normally affect life expectancy. The major complications from IIH arise from untreated or treatment-resistant papilledema. In various case series, the long-term risk of one’s vision being significantly affected by IIH is reported to lie anywhere between 10 and 25%.[5][9]

• #9 Idiopathic intracranial hypertension (pseudotumor cerebri): Prognosis and treatment – UpToDate

  https://www.uptodate.com/contents/idiopathic-intracranial-hypertension-pseudotumor-cerebri-prognosis-and-treatment

  Permanent disabling vision loss is the major morbidity associated with IIH but is uncommon. While an early, hospital-based study found that 24 percent of 57 patients developed blindness or severe visual impairment, subsequent studies that have been outpatient based have found a lower rate of severe visual loss of 6 to 14 percent. […] A recurrence of symptoms may occur in 8 to 38 percent of patients after recovery from an episode of IIH or after a prolonged period of stability. Weight gain is a common but not universal antecedent to recurrent IIH. […] Most patients with IIH improve or stabilize with medical treatment over the course of several months. Recurrences may occur even after several years, necessitating ongoing monitoring.

• #10 Improving pediatric idiopathic intracranial hypertension care: a retrospective cohort study | Scientific Reports

  https://www.nature.com/articles/s41598-022-23960-w

  To describe the clinical course and prognosis of pediatric idiopathic intracranial hypertension (IIH) and examine the preferred management setting. […] IIH is a preventable cause of vision loss in children. Hence, a rapid diagnosis followed by prompt treatment and follow-up is essential. […] Nonetheless, permanent visual impairment and relapse have been reported in up to 10% and 24% of pediatric patients, respectively. […] High-grade papilledema and weight gain during the disease course have been established as predictors of poor visual outcome and a higher recurrence rate. […] The main objective of this study was to compare the short- and long-term outcomes of pediatric IIH patients followed in different clinical settings using unscheduled IIH-related emergency room (ER) visits and hospitalizations as markers of poor outcome.

• #11 Idiopathic Intracranial Hypertension: Prognostic Factors and Multidisciplinary Management

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5572623/

  Idiopathic intracranial hypertension (IIH) mostly affects young obese women and can lead to permanent visual impairment. However, prognostic factors and therapeutic strategy remain unclear. […] Weight gain, rather than initial weight, emerged as the leading factor of poor visual outcome in patients with IIH, followed by presence of bilateral TSS. […] Our results indicate that the first reason for poor IIH prognosis is weight gain followed by bilateral TSS. […] In patients with IIH, weight gain, as opposed to initial BMI, is the leading factor of poor visual outcome. Other identified criteria, but to a lesser extent, are bilateral TSS in the overall population and older age in patients with bilateral TSS only. This emphasizes cross-links between weight gain and high cerebral venous pressure in the pathogenesis of IIH. Unilateral TSS stenting appears to be a safe and effective treatment to overcome this pathological circle in patients with bilateral TSS but should be reserved only after measures are undertaken to achieve weight loss.

• #12 Improving pediatric idiopathic intracranial hypertension care: a retrospective cohort study | Scientific Reports

  https://www.nature.com/articles/s41598-022-23960-w

  To describe the clinical course and prognosis of pediatric idiopathic intracranial hypertension (IIH) and examine the preferred management setting. […] IIH is a preventable cause of vision loss in children. Hence, a rapid diagnosis followed by prompt treatment and follow-up is essential. […] Nonetheless, permanent visual impairment and relapse have been reported in up to 10% and 24% of pediatric patients, respectively. […] High-grade papilledema and weight gain during the disease course have been established as predictors of poor visual outcome and a higher recurrence rate. […] The main objective of this study was to compare the short- and long-term outcomes of pediatric IIH patients followed in different clinical settings using unscheduled IIH-related emergency room (ER) visits and hospitalizations as markers of poor outcome.

• #13 Idiopathic Intracranial Hypertension: Prognostic Factors and Multidisciplinary Management

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5572623/

  Idiopathic intracranial hypertension (IIH) mostly affects young obese women and can lead to permanent visual impairment. However, prognostic factors and therapeutic strategy remain unclear. […] Weight gain, rather than initial weight, emerged as the leading factor of poor visual outcome in patients with IIH, followed by presence of bilateral TSS. […] Our results indicate that the first reason for poor IIH prognosis is weight gain followed by bilateral TSS. […] In patients with IIH, weight gain, as opposed to initial BMI, is the leading factor of poor visual outcome. Other identified criteria, but to a lesser extent, are bilateral TSS in the overall population and older age in patients with bilateral TSS only. This emphasizes cross-links between weight gain and high cerebral venous pressure in the pathogenesis of IIH. Unilateral TSS stenting appears to be a safe and effective treatment to overcome this pathological circle in patients with bilateral TSS but should be reserved only after measures are undertaken to achieve weight loss.

• #14 Idiopathic Intracranial Hypertension (IIH): Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1214410-overview

  Since IIH tends to be chronic, visual function (visual acuity, visual fields, optic nerve appearance) must be monitored for years after presentation. If necessary, medical treatment should be continued on a long-term basis. […] In the IIHTT the 3 most important negative risk factors for poor prognosis related to progressive visual field loss were male gender, high-grade papilledema and decreased visual acuity at baseline.

• #15 Improving pediatric idiopathic intracranial hypertension care: a retrospective cohort study | Scientific Reports

  https://www.nature.com/articles/s41598-022-23960-w

  To describe the clinical course and prognosis of pediatric idiopathic intracranial hypertension (IIH) and examine the preferred management setting. […] IIH is a preventable cause of vision loss in children. Hence, a rapid diagnosis followed by prompt treatment and follow-up is essential. […] Nonetheless, permanent visual impairment and relapse have been reported in up to 10% and 24% of pediatric patients, respectively. […] High-grade papilledema and weight gain during the disease course have been established as predictors of poor visual outcome and a higher recurrence rate. […] The main objective of this study was to compare the short- and long-term outcomes of pediatric IIH patients followed in different clinical settings using unscheduled IIH-related emergency room (ER) visits and hospitalizations as markers of poor outcome.

• #16 Idiopathic Intracranial Hypertension (IIH): Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1214410-overview

  Since IIH tends to be chronic, visual function (visual acuity, visual fields, optic nerve appearance) must be monitored for years after presentation. If necessary, medical treatment should be continued on a long-term basis. […] In the IIHTT the 3 most important negative risk factors for poor prognosis related to progressive visual field loss were male gender, high-grade papilledema and decreased visual acuity at baseline.

• #17 Idiopathic Intracranial Hypertension (IIH): Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1214410-overview

  Since IIH tends to be chronic, visual function (visual acuity, visual fields, optic nerve appearance) must be monitored for years after presentation. If necessary, medical treatment should be continued on a long-term basis. […] In the IIHTT the 3 most important negative risk factors for poor prognosis related to progressive visual field loss were male gender, high-grade papilledema and decreased visual acuity at baseline.

• #18 Idiopathic Intracranial Hypertension: Prognostic Factors and Multidisciplinary Management

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5572623/

  Idiopathic intracranial hypertension (IIH) mostly affects young obese women and can lead to permanent visual impairment. However, prognostic factors and therapeutic strategy remain unclear. […] Weight gain, rather than initial weight, emerged as the leading factor of poor visual outcome in patients with IIH, followed by presence of bilateral TSS. […] Our results indicate that the first reason for poor IIH prognosis is weight gain followed by bilateral TSS. […] In patients with IIH, weight gain, as opposed to initial BMI, is the leading factor of poor visual outcome. Other identified criteria, but to a lesser extent, are bilateral TSS in the overall population and older age in patients with bilateral TSS only. This emphasizes cross-links between weight gain and high cerebral venous pressure in the pathogenesis of IIH. Unilateral TSS stenting appears to be a safe and effective treatment to overcome this pathological circle in patients with bilateral TSS but should be reserved only after measures are undertaken to achieve weight loss.

• #19 Idiopathic Intracranial Hypertension (IIH): Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1214410-overview

  Idiopathic intracranial hypertenion (IIH) is not known to be associated with any specific mortality risk, but endovascular and surgical treatments (eg, venous sinus stenting or shunting) may cause morbidity and mortality. The increased mortality associated with morbid obesity has a selective expression in this group because of the strong predilection of the disease to affect obese females. […] The morbidity of IIH mainly is related to the effects of papilledema on visual function. If left untreated, long-standing disc edema results in an irreversible optic neuropathy with accompanying constriction of the visual field and loss of color vision. In end-stage papilledema, central visual acuity also is involved. With timely and appropriate treatment of IIH, the visual prognosis can be encouraging.

• #20 Idiopathic Intracranial Hypertension: Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/21968-idiopathic-intracranial-hypertension

  IIH is rare. It affects an estimated .2 to 2 people (between ages 25 and 36) out of 100,000 in a general population study. […] IIH isn’t life-threatening. However, symptoms can cause permanent vision changes that can affect your quality of life. A healthcare provider can quickly treat this condition to prevent complications. […] IIH may lead to vision loss if untreated. This is irreversible. A healthcare provider can offer treatment options to prevent this complication, so let them know as soon as possible if you notice changes to your vision. […] The goals of IIH treatment are to decrease pressure on your brain and prevent vision loss. […] Timely treatment at the first sign of vision changes or symptoms can help reduce your risk of complications like permanent vision loss. Treatment is often successful at relieving symptoms. Your healthcare provider can give you the best information on what you can expect in your situation. […] IIH doesn’t directly affect your life expectancy. Most people have a normal life expectancy. […] There isn’t a cure for IIH, so you may have to manage this condition for the rest of your life.

• #21 Idiopathic Intracranial Hypertension (IIH): Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1214410-overview

  Since IIH tends to be chronic, visual function (visual acuity, visual fields, optic nerve appearance) must be monitored for years after presentation. If necessary, medical treatment should be continued on a long-term basis. […] In the IIHTT the 3 most important negative risk factors for poor prognosis related to progressive visual field loss were male gender, high-grade papilledema and decreased visual acuity at baseline.

• #22 Improving pediatric idiopathic intracranial hypertension care: a retrospective cohort study | Scientific Reports

  https://www.nature.com/articles/s41598-022-23960-w

  We hypothesized that multidisciplinary follow-up would improve patient care and decrease the need for unscheduled IIH-related hospitalizations and ER visits compared to follow-up by individual specialists. […] The type of follow-up was the only significant factor associated with recurrent unscheduled ER and hospital admissions. […] In agreement with our initial hypothesis, we found that children who were under the care of a multidisciplinary team in a tertiary center had significantly lower odds of returning to the hospital, a lower rate of resulting inpatient days, as well as longer time intervals between hospital returns, compared to children followed by individual specialists elsewhere. […] This multidisciplinary approach improves the outcome of children with IIH compared to follow-ups by specialists in other settings. […] Decreased rates of recurrent IIH-related hospital returns and hospitalization days and longer time to hospital returns were related to multidisciplinary follow-up in tertiary center clinics compared to follow-up in community clinics.

• #23 Improving pediatric idiopathic intracranial hypertension care: a retrospective cohort study | Scientific Reports

  https://www.nature.com/articles/s41598-022-23960-w

  We hypothesized that multidisciplinary follow-up would improve patient care and decrease the need for unscheduled IIH-related hospitalizations and ER visits compared to follow-up by individual specialists. […] The type of follow-up was the only significant factor associated with recurrent unscheduled ER and hospital admissions. […] In agreement with our initial hypothesis, we found that children who were under the care of a multidisciplinary team in a tertiary center had significantly lower odds of returning to the hospital, a lower rate of resulting inpatient days, as well as longer time intervals between hospital returns, compared to children followed by individual specialists elsewhere. […] This multidisciplinary approach improves the outcome of children with IIH compared to follow-ups by specialists in other settings. […] Decreased rates of recurrent IIH-related hospital returns and hospitalization days and longer time to hospital returns were related to multidisciplinary follow-up in tertiary center clinics compared to follow-up in community clinics.

• #24 Idiopathic Intracranial Hypertension: Prognostic Factors and Multidisciplinary Management

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5572623/

  Idiopathic intracranial hypertension (IIH) mostly affects young obese women and can lead to permanent visual impairment. However, prognostic factors and therapeutic strategy remain unclear. […] Weight gain, rather than initial weight, emerged as the leading factor of poor visual outcome in patients with IIH, followed by presence of bilateral TSS. […] Our results indicate that the first reason for poor IIH prognosis is weight gain followed by bilateral TSS. […] In patients with IIH, weight gain, as opposed to initial BMI, is the leading factor of poor visual outcome. Other identified criteria, but to a lesser extent, are bilateral TSS in the overall population and older age in patients with bilateral TSS only. This emphasizes cross-links between weight gain and high cerebral venous pressure in the pathogenesis of IIH. Unilateral TSS stenting appears to be a safe and effective treatment to overcome this pathological circle in patients with bilateral TSS but should be reserved only after measures are undertaken to achieve weight loss.

• #25 Idiopathic Intracranial Hypertension (IIH): Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1214410-overview

  Idiopathic intracranial hypertenion (IIH) is not known to be associated with any specific mortality risk, but endovascular and surgical treatments (eg, venous sinus stenting or shunting) may cause morbidity and mortality. The increased mortality associated with morbid obesity has a selective expression in this group because of the strong predilection of the disease to affect obese females. […] The morbidity of IIH mainly is related to the effects of papilledema on visual function. If left untreated, long-standing disc edema results in an irreversible optic neuropathy with accompanying constriction of the visual field and loss of color vision. In end-stage papilledema, central visual acuity also is involved. With timely and appropriate treatment of IIH, the visual prognosis can be encouraging.

• #26 Improving pediatric idiopathic intracranial hypertension care: a retrospective cohort study | Scientific Reports

  https://www.nature.com/articles/s41598-022-23960-w

  To describe the clinical course and prognosis of pediatric idiopathic intracranial hypertension (IIH) and examine the preferred management setting. […] IIH is a preventable cause of vision loss in children. Hence, a rapid diagnosis followed by prompt treatment and follow-up is essential. […] Nonetheless, permanent visual impairment and relapse have been reported in up to 10% and 24% of pediatric patients, respectively. […] High-grade papilledema and weight gain during the disease course have been established as predictors of poor visual outcome and a higher recurrence rate. […] The main objective of this study was to compare the short- and long-term outcomes of pediatric IIH patients followed in different clinical settings using unscheduled IIH-related emergency room (ER) visits and hospitalizations as markers of poor outcome.

• #27 Idiopathic intracranial hypertension – Wikipedia

  https://en.wikipedia.org/wiki/Idiopathic_intracranial_hypertension

  Prognosis Variable[2] […] It is not known what percentage of people with IIH will remit spontaneously, and what percentage will develop chronic disease.[9] […] IIH does not normally affect life expectancy. The major complications from IIH arise from untreated or treatment-resistant papilledema. In various case series, the long-term risk of one’s vision being significantly affected by IIH is reported to lie anywhere between 10 and 25%.[5][9]

• #28 Idiopathic Intracranial Hypertension: Prognostic Factors and Multidisciplinary Management

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5572623/

  Idiopathic intracranial hypertension (IIH) mostly affects young obese women and can lead to permanent visual impairment. However, prognostic factors and therapeutic strategy remain unclear. […] Weight gain, rather than initial weight, emerged as the leading factor of poor visual outcome in patients with IIH, followed by presence of bilateral TSS. […] Our results indicate that the first reason for poor IIH prognosis is weight gain followed by bilateral TSS. […] In patients with IIH, weight gain, as opposed to initial BMI, is the leading factor of poor visual outcome. Other identified criteria, but to a lesser extent, are bilateral TSS in the overall population and older age in patients with bilateral TSS only. This emphasizes cross-links between weight gain and high cerebral venous pressure in the pathogenesis of IIH. Unilateral TSS stenting appears to be a safe and effective treatment to overcome this pathological circle in patients with bilateral TSS but should be reserved only after measures are undertaken to achieve weight loss.

• #29 Idiopathic intracranial hypertension (pseudotumor cerebri): Prognosis and treatment – UpToDate

  https://www.uptodate.com/contents/idiopathic-intracranial-hypertension-pseudotumor-cerebri-prognosis-and-treatment

  Permanent disabling vision loss is the major morbidity associated with IIH but is uncommon. While an early, hospital-based study found that 24 percent of 57 patients developed blindness or severe visual impairment, subsequent studies that have been outpatient based have found a lower rate of severe visual loss of 6 to 14 percent. […] A recurrence of symptoms may occur in 8 to 38 percent of patients after recovery from an episode of IIH or after a prolonged period of stability. Weight gain is a common but not universal antecedent to recurrent IIH. […] Most patients with IIH improve or stabilize with medical treatment over the course of several months. Recurrences may occur even after several years, necessitating ongoing monitoring.

• #30 Improving pediatric idiopathic intracranial hypertension care: a retrospective cohort study | Scientific Reports

  https://www.nature.com/articles/s41598-022-23960-w

  We hypothesized that multidisciplinary follow-up would improve patient care and decrease the need for unscheduled IIH-related hospitalizations and ER visits compared to follow-up by individual specialists. […] The type of follow-up was the only significant factor associated with recurrent unscheduled ER and hospital admissions. […] In agreement with our initial hypothesis, we found that children who were under the care of a multidisciplinary team in a tertiary center had significantly lower odds of returning to the hospital, a lower rate of resulting inpatient days, as well as longer time intervals between hospital returns, compared to children followed by individual specialists elsewhere. […] This multidisciplinary approach improves the outcome of children with IIH compared to follow-ups by specialists in other settings. […] Decreased rates of recurrent IIH-related hospital returns and hospitalization days and longer time to hospital returns were related to multidisciplinary follow-up in tertiary center clinics compared to follow-up in community clinics.

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