Przetoka pochwy
Patofizjologia i mechanizm

Przetoka pochwy stanowi patologiczne połączenie między ścianą pochwy a sąsiednimi narządami, najczęściej pęcherzem moczowym, cewką moczową, moczowodami lub odbytnicą. Patogeneza opiera się na uszkodzeniu tkanek prowadzącym do ich niedokrwienia, martwicy i powstania kanału przetoki, co skutkuje niekontrolowanym przepływem moczu, gazów lub kału przez pochwę. Mechanizmy powstawania przetok różnią się w zależności od etiologii, obejmując przedłużony poród (ucisk tkanek przez główkę płodu przez 3-5 dni), urazy operacyjne (np. histerektomia, cięcie cesarskie), radioterapię (obliteracyjne zapalenie tętnic), choroby zapalne jelit (np. choroba Leśniowskiego-Crohna) oraz nowotwory miednicy. Czynniki ryzyka to m.in. palenie tytoniu, cukrzyca, otyłość, wcześniejsza radioterapia, niedożywienie i choroby układowe. Przetoki pęcherzowo-pochwowe i odbytniczo-pochwowe charakteryzują się specyficznymi cechami histopatologicznymi i klinicznymi, a ich lokalizacja i rozległość wpływają na rokowanie i wybór metody leczenia.

Definicja przetoki pochwy

Przetoka pochwy to nieprawidłowe połączenie lub otwór, który tworzy się między ścianą pochwy a sąsiednim narządem. Najczęściej przetoki powstają między pochwą a narządami układu moczowego (pęcherz moczowy, cewka moczowa, moczowody) lub układu pokarmowego (odbytnica, jelito cienkie lub grube). To nieprawidłowe połączenie prowadzi do niekontrolowanego przepływu moczu, gazów lub kału przez pochwę, co powoduje znaczne pogorszenie jakości życia pacjentek.123

Patogeneza przetoki pochwy

Podstawowy mechanizm powstawania przetok pochwowych wiąże się z uszkodzeniem tkanek, które prowadzi do ich martwicy i utworzenia nieprawidłowego połączenia. Proces patofizjologiczny można podzielić na kilka etapów:456

Mechanizm niedokrwienia tkankowego

Kluczowym elementem w patogenezie przetoki pochwy jest upośledzenie przepływu krwi do tkanek, co prowadzi do ich niedokrwienia (niedotlenienia). Niedokrwienie tkankowe może wynikać z:78

  • Przedłużonego ucisku tkanek podczas porodu, gdy główka płodu uciska na tkanki między kością łonową a pochwą
  • Urazu operacyjnego podczas zabiegów ginekologicznych
  • Uszkodzenia naczyń krwionośnych zaopatrujących ścianę pochwy lub pęcherza moczowego
  • Zmian popromiennych powodujących zwłóknienie naczyń (obliteracyjne zapalenie tętnic)
  • Procesów zapalnych prowadzących do niszczenia tkanek

910

Sekwencja zmian prowadzących do powstania przetoki

Proces powstawania przetoki pochwy przebiega według następującej sekwencji:1112

  1. Uszkodzenie tkanki i martwica – w wyniku urazu, niedokrwienia lub zapalenia dochodzi do obumierania komórek tkanki
  2. Proces zapalny – w odpowiedzi na uszkodzenie tkanek rozwija się reakcja zapalna
  3. Zaburzony proces regeneracji – rozpoczyna się proces regeneracji komórkowej, jednak jest on zaburzony z powodu utrzymującego się niedokrwienia lub stanu zapalnego
  4. Angiogeneza – rozpoczyna się tworzenie nowych naczyń krwionośnych
  5. Faza włóknienia – fibroblasty namnażają się i syntetyzują macierz pozakomórkową, szczególnie kolagen, co zazwyczaj osiąga maksimum około 7 dni po urazie i trwa przez kilka tygodni
  6. Tworzenie się blizny – proces przebudowy tkanki (remodeling) prowadzi do formowania się blizny
  7. Utworzenie przetoki – gdy proces gojenia jest zaburzony, dochodzi do utworzenia kanału przetoki, który następnie ulega nabłonkowaniu

1314

Okres 1-3 tygodni po urazie tkankowym jest najbardziej wrażliwy na zaburzenia w procesie gojenia, takie jak niedotlenienie, niedokrwienie, niedożywienie, radioterapia czy chemioterapia.15

Mechanizm powstawania przetoki pochwy w zależności od przyczyny

Przetoka powstała w wyniku przedłużonego porodu

W przypadku przedłużonego porodu główka płodu wywiera długotrwały ucisk na tkanki miękkie między jego głową a kością łonową matki. Prowadzi to do niedokrwienia tkanek, a w konsekwencji do martwicy i rozpadu, co skutkuje utworzeniem otworu między narządami. Proces ten trwa zazwyczaj od 3 do 5 dni po porodzie.161718

Przetoka powstała w następstwie zabiegów chirurgicznych

Przetoki pooperacyjne powstają najczęściej w wyniku:1920

  • Nierozpoznanego uszkodzenia pęcherza podczas trudnej histerektomii lub cięcia cesarskiego
  • Odwarstwiania pęcherza moczowego podczas mobilizacji płata pęcherzowego, co powoduje odnaczynienie lub niezauważone rozdarcie tylnej ściany pęcherza
  • Nieprawidłowego założenia szwów na sklepienie pochwy, które obejmują ścianę pęcherza moczowego, prowadząc do niedokrwienia, martwicy i powstania przetoki
  • Uszkodzenia moczowodu podczas preparowania więzadła jajnikowo-miednicznego lub podwiązywania naczyń macicznych
  • Nieoczekiwanego krwawienia miednicy, które może ograniczać widoczność podczas operacji i prowadzić do uszkodzenia moczowodu

21

Przetoka spowodowana radioterapią

Radioterapia prowadzi do powstawania przetok poprzez:2223

  • Wywołanie obliteracyjnego zapalenia tętnic
  • Przewlekłe niedokrwienie tkanek
  • Zaburzenie procesu gojenia
  • Regresję guza nowotworowego, która może prowadzić do powstania ubytku w tkance

24

Przetoka spowodowana chorobą zapalną

W przypadku chorób zapalnych, takich jak choroba Leśniowskiego-Crohna, wrzodziejące zapalenie jelita grubego, zapalenie uchyłków czy ropnie okołoodbytnicze, mechanizm powstawania przetoki obejmuje:2526

  • Przewlekły proces zapalny prowadzący do erozji ściany narządu
  • Tworzenie się ropni, które następnie przebijają się do sąsiednich struktur
  • Uszkodzenie integralności ściany jelita czy pochwy
  • Utworzenie kanału połączeniowego między narządami

27

Przetoka w przebiegu choroby nowotworowej

Nowotwory miednicy mniejszej, takie jak rak szyjki macicy, pochwy, odbytnicy czy pęcherza moczowego, mogą prowadzić do powstania przetok poprzez:2829

  • Bezpośrednią inwazję guza do sąsiednich narządów
  • Miejscowe niszczenie tkanek przez rozrastający się nowotwór
  • Martwicę centralną guza prowadzącą do powstania ubytku w tkance

30

Czynniki ryzyka powstawania przetok pochwowych

Istnieje szereg czynników, które zwiększają ryzyko powstania przetoki pochwy:3132

  • Palenie tytoniu – upośledza ukrwienie tkanek i proces gojenia
  • Cukrzyca – prowadzi do mikroangiopatii i zaburzenia ukrwienia tkanek
  • Otyłość – zwiększa ryzyko powikłań śródoperacyjnych i pooperacyjnych
  • Wcześniejsza radioterapia obszaru miednicy
  • Niedożywienie – zaburza procesy gojenia
  • Choroby układowe wpływające na gojenie ran
  • Brak dostępu do opieki medycznej podczas porodu (w krajach rozwijających się)
  • Niska masa ciała i niskorosłość związane z niedożywieniem, co może predysponować do trudności podczas porodu

3334

Specyficzne mechanizmy dla różnych typów przetok

Przetoka pęcherzowo-pochwowa (vesicovaginal fistula)

Przetoka pęcherzowo-pochwowa to nieprawidłowe połączenie między pęcherzem moczowym a pochwą, prowadzące do ciągłego wycieku moczu przez pochwę. Mechanizm jej powstawania zależy od czynnika wywołującego:3536

  • W krajach rozwiniętych najczęstszą przyczyną jest uraz podczas histerektomii, gdzie może dojść do uszkodzenia pęcherza moczowego
  • W krajach rozwijających się główną przyczyną jest przedłużony poród z uciskiem na przedział pęcherzowo-pochwowy, prowadzący do martwicy z niedokrwienia
  • Histopatologicznie przetoka wyścielona jest nabłonkiem płaskim od strony pochwy i nabłonkiem przejściowym od strony pęcherza, często z ogniskami owrzodzeń i włóknienia

37

Przetoka odbytniczo-pochwowa (rectovaginal fistula)

Przetoka odbytniczo-pochwowa to nieprawidłowe połączenie między odbytnicą a pochwą. Jej specyfika patogenetyczna obejmuje:3839

  • Uszkodzenia okołoporodowe, szczególnie związane z epizjoproktotomią (nacięcie krocza)
  • Nierozpoznanie i niewłaściwe zaopatrzenie pęknięć krocza
  • Wtórne zakażenie pęknięć krocza
  • Przedłużony poród z uciskiem na przegrodę odbytniczo-pochwową
  • Zabiegi operacyjne na pochwie lub odbytnicy, zwłaszcza te wykonywane w pobliżu linii grzebieniastej
  • Choroby zapalne jelit, zwłaszcza choroba Leśniowskiego-Crohna
  • Powikłania chirurgicznych zabiegów związanych z hemoroidami (np. hemoroidopeksja z użyciem staplera)

4041

Przetoki odbytniczo-pochwowe mogą wiązać się z uszkodzeniem zwieraczy odbytu (wewnętrznego i zewnętrznego), co ma istotne znaczenie dla funkcji trzymania stolca.42

Przetoka moczowodowo-pochwowa (ureterovaginal fistula)

Przetoki moczowodowo-pochwowe to nieprawidłowe połączenia między światłem moczowodu a pochwą. Ich patogeneza obejmuje:4344

  • Najczęściej są powikłaniem histerektomii
  • Mogą powstać w wyniku urazu moczowodu podczas preparowania w okolicy więzadła jajnikowo-miednicznego lub podwiązywania naczyń macicznych
  • Nieoczekiwane krwawienie miednicy może ograniczyć widoczność podczas operacji i prowadzić do urazu moczowodu
  • Rzadziej mogą być związane z urazem miednicy lub radioterapią nowotworów miednicy
  • Mogą współistnieć z przetokami pęcherzowo-pochwowymi, jednak ich rozpoznanie i leczenie różni się istotnie

45

Mechanizmy reperacyjne i gojenie przetok

Zrozumienie mechanizmów gojenia przetok ma kluczowe znaczenie dla skutecznego leczenia:4647

  • Kluczowym elementem gojenia jest przywrócenie prawidłowego ukrwienia tkanek
  • Zachowanie zdrowych, dobrze ukrwionych marginesów podczas operacji naprawczych
  • Usunięcie tkanki bliznowatej i martwiczej
  • Unikanie napięcia w linii szwów
  • Zapewnienie dobrego drenażu pęcherza moczowego po zabiegu naprawczym
  • Właściwy dobór materiału szewnego – zastosowanie niewchłanialnych lub wolno wchłanialnych szwów
  • Przy dużych ubytkach tkankowych konieczne może być zastosowanie przeszczepów tkankowych lub płatów

4849

W przypadku przetok popromiennych szczególne znaczenie ma wprowadzenie dobrze ukrwionej tkanki do obszaru, gdzie występuje niedokrwienie popromienne. Technika płata Martiusa (wykorzystująca mięsień opuszkowo-jamisty i tkankę tłuszczową warg sromowych) jest stosowana z powodzeniem w leczeniu tych trudnych przypadków.50

Czynniki wpływające na skuteczność leczenia przetok

Skuteczność leczenia przetok pochwowych zależy od wielu czynników:515253

  • Wielkość pęcherza moczowego – mały pęcherz jest niekorzystnym czynnikiem prognostycznym
  • Stopień zwłóknienia pochwy – silne zwłóknienie utrudnia gojenie
  • Stopień uszkodzenia cewki moczowej – uszkodzenie cewki zwiększa ryzyko nietrzymania moczu po operacji
  • Lokalizacja przetoki – przetoki położone wysoko lub blisko ujść moczowodowych są trudniejsze w leczeniu
  • Długość cewki moczowej – krótka cewka zwiększa ryzyko niewydolności mechanizmu zwieraczowego
  • Czy przetoka jest okrężna – przetoki okrężne są trudniejsze w leczeniu
  • Wcześniejsze nieudane próby naprawy – zwiększają ryzyko niepowodzenia kolejnych operacji
  • Doświadczenie chirurga – istotnie wpływa na powodzenie zabiegu

5455

Niepowodzenia w leczeniu przetok mogą wynikać z rozległego włóknienia, zwłaszcza w przypadku wcześniejszych nieudanych napraw i u pacjentek z długotrwałymi objawami.56

Powikłania i następstwa przetok pochwowych

Najczęstsze powikłania występujące po operacjach naprawczych przetok pochwowych to:5758

  • Nawrót przetoki – główne powikłanie operacji przetok pęcherzowo-pochwowych
  • Częstomocz i parcia naglące – najczęściej występują w ostrym okresie okołooperacyjnym
  • Nietrzymanie moczu wysiłkowe i z parcia – uznawane za długotrwałe powikłania naprawy przetok pęcherzowo-pochwowych
  • Nietrzymanie moczu wysiłkowe – szczególnie częste w przypadkach przetok o podłożu położniczym, gdy doszło do uszkodzenia mechanizmu zwieraczowego
  • Zaburzenia funkcji seksualnych wynikające ze zwężenia pochwy
  • Stany zapalne i zakażenia dróg moczowych
  • Zwężenie odbytnico – może wymagać wykonania kolostomii

59

Nietrzymanie moczu występuje u około 10% pacjentek z przetokami położniczymi i jest związane z dużymi przetokami. Uszkodzenie cewki moczowej w przebiegu przetoki położniczej jest znanym czynnikiem ryzyka nietrzymania moczu resztkowego po naprawie przetoki.60

Czynniki, które niezależnie przewidują nietrzymanie moczu resztkowe po naprawie obejmują: zaangażowanie cewki moczowej, mały pęcherz, bliznowacenie pochwy i wielkość przetoki.61

Nowoczesne metody leczenia chirurgicznego przetok

Współczesne podejście do leczenia przetok pochwowych obejmuje różne techniki chirurgiczne:626364

  • Zabieg przezpochwowy – ma najniższe ryzyko powikłań i jest preferowaną metodą, gdy pozwala na to lokalizacja i złożoność przetoki
  • Zabieg przez powłoki brzuszne – stosowany przy wysokim położeniu przetoki lub gdy dostęp przez pochwę jest utrudniony
  • Chirurgia laparoskopowa – mniej inwazyjna metoda z mniejszymi nacięciami, mniejszym bólem i krótszym okresem rekonwalescencji w porównaniu do tradycyjnej operacji otwartej
  • Chirurgia robotyczna – minimalizuje wielkość nacięcia i ilość bólu dla pacjenta
  • Technika NOTES (Natural Orifice Transluminal Endoscopic Surgery) przez pochwę – umożliwia dokładną kontrolę wizualną tkanek podczas operacji

656667

Wskazania do zastosowania dostępu przezbrzusznego lub przezpęcherzowego obejmują:68

  • Przetokę położoną wysoko i wąską pochwę
  • Przetokę położoną blisko ujść moczowodowych
  • Wcześniejszą nieudaną naprawę
  • Dużą lub złożoną przetokę
  • Konieczność zastosowania przeszczepu tkankowego

69

Technika V-NOTES (pochwowa chirurgia endoskopowa przez naturalne otwory ciała) umożliwia dokładne badanie jamy otrzewnej i ciągłą kontrolę wizualną otaczających tkanek, co pozwala przezwyciężyć ograniczenia tradycyjnej chirurgii pochwowej. Skuteczność gojenia przetok tą metodą wynosi 82-100%.70

Zasady leczenia chirurgicznego przetok

Niezależnie od wybranej techniki, podstawowe zasady chirurgicznego leczenia przetok obejmują:7172

  1. Dokładną przedoperacyjną ocenę i przygotowanie pacjentki
  2. Odpowiedni czas wykonania zabiegu (gdy ostry stan zapalny ustąpi)
  3. Perfekcyjną aseptykę i dobre uwidocznienie przetoki
  4. Minimalne wycięcie tkanki bliznowatej na brzegach
  5. Obecność zdrowych, dobrze ukrwionych marginesów
  6. Mobilizację ściany pęcherza od pochwy (w przypadku przetok pęcherzowo-pochwowych)
  7. Naprawę bez napięcia w dwóch warstwach
  8. Zastosowanie cienkiego materiału szewnego
  9. Minimalne wykorzystanie elektrokoagulacji
  10. Pooperacyjny drenaż pęcherza moczowego

73

W przypadku przetok odbytniczo-pochwowych, droga przetoki powinna zostać usunięta, aby umożliwić zdrowej tkance o dobrym ukrwieniu zespolenie. Jeśli tkanka w pobliżu drogi przetoki ma słabe ukrwienie, może być umieszczony przeszczep lub płat, aby wspomóc gojenie. Przeszczepy lub płaty mogą pochodzić z własnej tkanki tłuszczowej lub mięśniowej pacjentki i są umieszczane nad naprawioną drogą przetoki. Mogą być również stosowane inne przeszczepy biologiczne pobrane z tkanki zwierzęcej lub ludzkich zwłok.74

Patogeneza i mechanizm przetoki pochwy – podsumowanie

Przetoka pochwy to patologiczne połączenie między pochwą a innym narządem, najczęściej pęcherzem moczowym lub odbytnicą. Kluczowym elementem patogenezy jest uszkodzenie tkanek prowadzące do ich niedokrwienia, martwicy i rozpadu, co skutkuje utworzeniem nieprawidłowego kanału. Mechanizm powstawania przetoki różni się w zależności od przyczyny – czy jest to przedłużony poród, zabieg chirurgiczny, radioterapia, choroba zapalna czy nowotworowa.757677

Zrozumienie patofizjologii przetok pochwowych ma kluczowe znaczenie dla właściwego doboru metody leczenia, czasowania zabiegu oraz przewidywania potencjalnych powikłań. Współczesne metody diagnostyczne, w tym obrazowanie metodą rezonansu magnetycznego i tomografii komputerowej, pozwalają na precyzyjne określenie anatomii przetoki i zaplanowanie optymalnego postępowania terapeutycznego.78

Większość przetok pochwowych wymaga leczenia chirurgicznego, które przy właściwej kwalifikacji pacjentek i doświadczeniu chirurga ma wysoką skuteczność. Kluczowe znaczenie ma wybór optymalnego dostępu operacyjnego oraz przestrzeganie zasad atraumatycznej techniki operacyjnej z zapewnieniem dobrego ukrwienia tkanek w linii zespolenia.7980

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  1. 11.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Vaginal Fistula: Types, Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/22079-vaginal-fistula
    Prolonged labor, trauma and pelvic surgeries can cause vaginal fistulas. These openings form when vaginal tissue dies, creating a hole between your vagina and organs in the urinary or digestive systems. A vaginal fistula is an abnormal connection or opening that develops between your vaginal wall and a nearby organ. Most often, they develop between your vagina and an organ in your urinary system or in your digestive system. They most often occur due to damage to your vaginal tissue from things like childbirth, surgery, injury or infection. A lack of blood supply to vaginal tissue causes the tissue to die or become damaged. A hole or fistula forms in the tissue where this damage occurs. These openings can develop in a few days or over several years. Causes of vaginal fistulas include: Prolonged labor during childbirth. Vaginal tears during childbirth or an episiotomy. Abdominal or pelvic surgery, including C-sections and hysterectomies. Cancer in your pelvic area, like cervical cancer or colorectal (colon) cancer. Inflammatory bowel diseases (IBD) like Crohns disease and ulcerative colitis. Colon infections like diverticulitis. Radiation therapy to the pelvic region. Trauma or injury. Surgical treatments for vaginal fistulas are highly successful. Most women experience a full recovery and no longer have symptoms.
  • #2 Rectovaginal Fistula – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK535350/
    A fistula is an abnormal connection between 2 epithelial surfaces. This is a general definition that applies to most of the known fistula but not all of them. The general description differentiates fistulae from sinuses, abscesses, and other forms of luminal tracts or extra-luminal collections. Fistula connects two surfaces or lumens. It begins on the offending side and makes its way to an adjacent lumen or surface. It follows the easiest and shortest path to the adjacent organ. Recto-vaginal fistula starts from the rectum and extends to the vagina. This activity describes the pathophysiology, etiology, and presentation of rectovaginal fistula and highlights the role of the interprofessional team in its management. […] Like other fistulae, RVF is a result of a complication of an underlying disease, surgical procedure, or injury. A good understanding of the pathophysiological process helps to assess better, manage, and prevent fistulae. Loss of wall integrity with ongoing inflammatory, infectious, or neoplastic processes at the rectal or vaginal wall can lead to erosion to the adjacent tissue or organ and establish an abnormal fistulous connection. When the initial process is reversible or curable, such as diverticulitis, fistulae have a better chance to resolve.
  • #3 Vaginal fistula: Types, symptoms, and causes
    https://www.medicalnewstoday.com/articles/vaginal-fistula
    A vaginal fistula is an opening that connects the vagina to another organ, such as the bladder, rectum, or bowel. They usually develop after tissue damage or trauma from childbirth, surgery, infections, cancer, or a chronic condition. […] A vaginal fistula is an opening or hole that forms between the vaginal wall and another organ to which it is not normally connected. In females, fistulas involving the genitals and surrounding organs are common. They may occur due to difficult childbirths, pelvic surgery, infections, inflammation, or cancer treatment in the pelvis or genital area. […] Vaginal fistulas develop after tissue damage. Common causes include trauma from a vaginal birth, such as vaginal tears, abdominal or pelvic surgeries, including hysterectomy and cesarean section, radiation therapy for gynecologic cancer, cancers in the pelvic area, including colon cancer, cervical cancer, and vaginal cancer, infections, chronic illnesses, such as Crohns disease and diverticulitis, and a foreign body in the vagina. […] Vaginal fistulas describe openings between the vagina and other organs, such as the rectum, bowel, and bladder, which are not normally present. These openings may occur due to pelvic surgery, childbirth, or radiation treatment for cancer.
  • #4 Vesico vaginal fistula | PPT
    https://www.slideshare.net/slideshow/vesico-vaginal-fistula-242999654/242999654
    1. PATHOPHYSIOLOGY TISSUE DAMAGE AND NECROSIS AFTER INJURY CAUSES INFLAMMATION PROCESS OF CELL REGENERATION BEGINS ANGIO-GENESIS STARTS FIRST FIBROBLASTS PROLIFERATE AND SUBSEQUENTLY SYNTHESIZE AND DEPOSIT EXTRACELLULAR MATRIX, PARTICULARLY COLLAGEN (FIBROSIS PHASE) COLLAGEN DEPOSITION PEAKS APPROXIMATELY 7 DAYS AFTER INJURY AND CONTINUES FOR SEVERAL WEEKS SUBSEQUENTLY SCAR FORMATION AND ORGANIZATION (REMODELLING) AUGMENTS WOUND STRENGTH ANY DISRUPTION IN THIS SEQUENCE EVENTUALLY MAY CREATE A FISTULA 1-3 WEEKS AFTER TISSUE INJURY IS MOST VULNERABLE TIME TO ALTERATION IN HEALING ENVIRONMENT AS HYPOXIA, ISCHEMIA, MALNUTRITION, RADIATION OR CHEMOTHERAPY. EDGES OF WOUND EPITHELIALIZE TO FORM CHRONIC FISTULOUS TRACT […] […] 11. Etio-pathogenesis In developing countries, most common (70 %) cause is obstetrical due to ischemia or trauma. Ischemia result from- Prolonged compression on the bladder base between fetal head and symphysis pubis in obstructed labor Ischemic necrosis infection sloughing fistula develops in 3-5 days of delivery. Traumatic- caused during instrumental vaginal delivery as forceps application or destructive operation (craniotomy) or may occur during cesarean or cesarean hysterectomy. […]
  • #5 Vaginal Fistula: Types, Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/22079-vaginal-fistula
    Prolonged labor, trauma and pelvic surgeries can cause vaginal fistulas. These openings form when vaginal tissue dies, creating a hole between your vagina and organs in the urinary or digestive systems. A vaginal fistula is an abnormal connection or opening that develops between your vaginal wall and a nearby organ. Most often, they develop between your vagina and an organ in your urinary system or in your digestive system. They most often occur due to damage to your vaginal tissue from things like childbirth, surgery, injury or infection. A lack of blood supply to vaginal tissue causes the tissue to die or become damaged. A hole or fistula forms in the tissue where this damage occurs. These openings can develop in a few days or over several years. Causes of vaginal fistulas include: Prolonged labor during childbirth. Vaginal tears during childbirth or an episiotomy. Abdominal or pelvic surgery, including C-sections and hysterectomies. Cancer in your pelvic area, like cervical cancer or colorectal (colon) cancer. Inflammatory bowel diseases (IBD) like Crohns disease and ulcerative colitis. Colon infections like diverticulitis. Radiation therapy to the pelvic region. Trauma or injury. Surgical treatments for vaginal fistulas are highly successful. Most women experience a full recovery and no longer have symptoms.
  • #6 Vaginal Fistula: Symptoms & Causes | NewYork-Presbyterian
    https://www.nyp.org/womens/urogynecology/vaginal-fistula
    A vaginal fistula begins with a lack of blood supply to the vaginal tissue, which causes the tissue to weaken and die. The holes can take days or, in some cases, years to develop. The initial damage may be caused by traumatic injury, certain treatments, or disease in the area. […] Common causes of vaginal fistulas: […] A fistula begins with a lack of blood supply to the vaginal tissue, which causes the tissue to weaken and die. The holes can take days or, in some cases, years to develop. The initial damage may be caused by traumatic injury, certain treatments, or disease in the area.
  • #7 Obstetric fistula – Wikipedia
    https://en.wikipedia.org/wiki/Obstetric_fistula
    Obstetric fistula is a medical condition in which a hole develops in the birth canal as a result of childbirth. This can be between the vagina and rectum, ureter, or bladder. It can result in incontinence of urine or feces. Complications may include depression, infertility, and social isolation. […] The underlying mechanism is poor blood flow to the affected area for a prolonged period of time. […] Over the course of the three to five days of labor, the unborn child presses against the mother’s vagina very tightly, cutting off blood flow to the surrounding tissues between the vagina and the rectum and between the vagina and the bladder, causing the tissues to disintegrate and rot away. […] Obstetric fistulae can also be caused by poorly performed abortions, and pelvic fracture, cancer, or radiation therapy targeted at the pelvic area, inflammatory bowel disease (such as Crohn’s disease and ulcerative colitis). Other potential causes for the development of obstetric fistulae are sexual abuse and rape, especially in conflict/postconflict areas, and other trauma, such as surgical trauma. […] In the developed world, such as the US, the primary cause of obstetric fistulae, particularly rectovaginal fistulae, is the use of episiotomy and forceps.
  • #8 Transvaginal repair of apical vesicovaginal fistula via vaginal natural orifice transluminal endoscopic surgery (V-NOTES): a modified surgical technique and its outcomes | Scientific Reports
    https://www.nature.com/articles/s41598-024-82366-y
    A vesicovaginal fistula (VVF) is defined as a pathological anatomical junction between the dorsal bladder wall and the anterior vagina. The pathophysiological mechanism for this abnormal anatomic connection is a necrosis of both organ walls as a result of ischemia. […] The timing of VVF repair depends on its etiology, comorbidities, and the anticipated approach for fistula repair. The transvaginal approach is more suitable for early repair, is less invasive, and is associated with a 90% or higher success rate. […] To treat patients with vesicovaginal fistulas, we developed a surgical technique called modified transvaginal natural orifice transluminal endoscopic surgery (V-NOTES). This method demonstrated positive efficacy and was successfully applied to male patients with urine incontinence. By enabling a thorough examination of the peritoneal cavity and providing continuous visual surveillance of the surrounding tissues, it would overcome the limitations of vaginal surgery.
  • #9
    https://www.ics.org/committees/developingworld/publicawareness/obstetricfistulaanintroduction
    Obstetric fistula is a wholly preventable condition, provided that appropriate medical and obstetric facilities including emergency caesarean section are available. […] In developing countries, obstetric fistula is the result of prolonged or obstructed (blocked) labour, often lasting several days, when the unborn baby cannot pass through the pelvis. The pressure of the babys head for an abnormally long time on the blood vessels supplying the tissue of the vagina, bladder, urethra and rectum cuts off the supply of oxygen (ischaemia) and leads to the death of the affected tissue (necrosis). […] The immense number of obstetric fistulas occurring in developing countries is of great concern, particularly since they are preventable if the right facilities are in place. Since surgical repair is not always successful even in the very best hands, prevention is paramount.
  • #10 Elucidating vaginal fistulas on CT and MRI | Insights into Imaging | Full Text
    https://insightsimaging.springeropen.com/articles/10.1186/s13244-019-0812-9
    Vaginal fistulas (VF) represent abnormal communications between the vagina and either the distal portion of the digestive system or the lower urinary tract, but lack an accepted classification and standardised terminology. […] The spectrum of causes encompasses congenital and developmental abnormalities, inflammatory diseases, infections, tumours, sexual and obstetric trauma, irradiation and post-surgical injuries. […] Regardless of the underlying disorder, all VF result in substantial morbidity and severely impair the patients quality of life. […] Entero-VF may involve the sigmoid colon (colo-VF), rectum (recto-VF) or anus (ano-VF). Their underlying causes and mechanisms are summarised in Table 1. […] In developing countries, VF are still common and almost invariably secondary to obstructed labour. Conversely, despite advancements in open and laparoscopic surgical techniques, in the Western world, over 90% of all urinary VF now develop as iatrogenic complications of irradiation or surgical injury to either distal ureter or bladder. […] The ideal cross-sectional techniques depend on the anatomic site and affected organ. With appropriate acquisition and focused interpretation, state-of-the art CT and MRI provide optimal visualisation of entero- and urinary VF that is crucial for correct therapeutic choice and surgical planning.
  • #11 Vesico vaginal fistula | PPT
    https://www.slideshare.net/slideshow/vesico-vaginal-fistula-242999654/242999654
    1. PATHOPHYSIOLOGY TISSUE DAMAGE AND NECROSIS AFTER INJURY CAUSES INFLAMMATION PROCESS OF CELL REGENERATION BEGINS ANGIO-GENESIS STARTS FIRST FIBROBLASTS PROLIFERATE AND SUBSEQUENTLY SYNTHESIZE AND DEPOSIT EXTRACELLULAR MATRIX, PARTICULARLY COLLAGEN (FIBROSIS PHASE) COLLAGEN DEPOSITION PEAKS APPROXIMATELY 7 DAYS AFTER INJURY AND CONTINUES FOR SEVERAL WEEKS SUBSEQUENTLY SCAR FORMATION AND ORGANIZATION (REMODELLING) AUGMENTS WOUND STRENGTH ANY DISRUPTION IN THIS SEQUENCE EVENTUALLY MAY CREATE A FISTULA 1-3 WEEKS AFTER TISSUE INJURY IS MOST VULNERABLE TIME TO ALTERATION IN HEALING ENVIRONMENT AS HYPOXIA, ISCHEMIA, MALNUTRITION, RADIATION OR CHEMOTHERAPY. EDGES OF WOUND EPITHELIALIZE TO FORM CHRONIC FISTULOUS TRACT […] […] 11. Etio-pathogenesis In developing countries, most common (70 %) cause is obstetrical due to ischemia or trauma. Ischemia result from- Prolonged compression on the bladder base between fetal head and symphysis pubis in obstructed labor Ischemic necrosis infection sloughing fistula develops in 3-5 days of delivery. Traumatic- caused during instrumental vaginal delivery as forceps application or destructive operation (craniotomy) or may occur during cesarean or cesarean hysterectomy. […]
  • #12 Fistulas – Knowledge @ AMBOSS
    https://www.amboss.com/us/knowledge/fistulas/
    Pathophysiology: deficient anastomoses/sutures, improper healing following intervention (e.g., radiation), or trauma leakage of intestinal contents local infection abscess formation and/or erosion intestinal epithelial defect epithelial cells penetrating into deeper layers of the mucosa formation of a tube-like structure tube connecting to other organs or the body surface (fistula formation) […] Pathophysiology: fistula between bladder and bowel direct spread of intestinal bacteria to the bladder recurrent UTIs […] Pathophysiology: Prolonged compression of soft tissue between the maternal pelvic bones and fetal head maternal soft tissue pressure necrosis formation of fistulas.
  • #13 Vesico vaginal fistula | PPT
    https://www.slideshare.net/slideshow/vesico-vaginal-fistula-242999654/242999654
    1. PATHOPHYSIOLOGY TISSUE DAMAGE AND NECROSIS AFTER INJURY CAUSES INFLAMMATION PROCESS OF CELL REGENERATION BEGINS ANGIO-GENESIS STARTS FIRST FIBROBLASTS PROLIFERATE AND SUBSEQUENTLY SYNTHESIZE AND DEPOSIT EXTRACELLULAR MATRIX, PARTICULARLY COLLAGEN (FIBROSIS PHASE) COLLAGEN DEPOSITION PEAKS APPROXIMATELY 7 DAYS AFTER INJURY AND CONTINUES FOR SEVERAL WEEKS SUBSEQUENTLY SCAR FORMATION AND ORGANIZATION (REMODELLING) AUGMENTS WOUND STRENGTH ANY DISRUPTION IN THIS SEQUENCE EVENTUALLY MAY CREATE A FISTULA 1-3 WEEKS AFTER TISSUE INJURY IS MOST VULNERABLE TIME TO ALTERATION IN HEALING ENVIRONMENT AS HYPOXIA, ISCHEMIA, MALNUTRITION, RADIATION OR CHEMOTHERAPY. EDGES OF WOUND EPITHELIALIZE TO FORM CHRONIC FISTULOUS TRACT […] […] 11. Etio-pathogenesis In developing countries, most common (70 %) cause is obstetrical due to ischemia or trauma. Ischemia result from- Prolonged compression on the bladder base between fetal head and symphysis pubis in obstructed labor Ischemic necrosis infection sloughing fistula develops in 3-5 days of delivery. Traumatic- caused during instrumental vaginal delivery as forceps application or destructive operation (craniotomy) or may occur during cesarean or cesarean hysterectomy. […]
  • #14 Rectovaginal Fistula: Practice Essentials, Anatomy, Pathophysiology
    https://emedicine.medscape.com/article/193277-overview
    The use of radiation to treat pelvic malignancies may give rise to RVFs. Fistulas that occur during such therapy usually result from tumor regression. […] A variety of infectious conditions can produce RVF. The most common are perirectal abscess/fistula and diverticulitis. Less commonly, tuberculosis, lymphogranuloma venereum, and Bartholin gland abscess can cause RVFs.
  • #15 Vesico vaginal fistula | PPT
    https://www.slideshare.net/slideshow/vesico-vaginal-fistula-242999654/242999654
    1. PATHOPHYSIOLOGY TISSUE DAMAGE AND NECROSIS AFTER INJURY CAUSES INFLAMMATION PROCESS OF CELL REGENERATION BEGINS ANGIO-GENESIS STARTS FIRST FIBROBLASTS PROLIFERATE AND SUBSEQUENTLY SYNTHESIZE AND DEPOSIT EXTRACELLULAR MATRIX, PARTICULARLY COLLAGEN (FIBROSIS PHASE) COLLAGEN DEPOSITION PEAKS APPROXIMATELY 7 DAYS AFTER INJURY AND CONTINUES FOR SEVERAL WEEKS SUBSEQUENTLY SCAR FORMATION AND ORGANIZATION (REMODELLING) AUGMENTS WOUND STRENGTH ANY DISRUPTION IN THIS SEQUENCE EVENTUALLY MAY CREATE A FISTULA 1-3 WEEKS AFTER TISSUE INJURY IS MOST VULNERABLE TIME TO ALTERATION IN HEALING ENVIRONMENT AS HYPOXIA, ISCHEMIA, MALNUTRITION, RADIATION OR CHEMOTHERAPY. EDGES OF WOUND EPITHELIALIZE TO FORM CHRONIC FISTULOUS TRACT […] […] 11. Etio-pathogenesis In developing countries, most common (70 %) cause is obstetrical due to ischemia or trauma. Ischemia result from- Prolonged compression on the bladder base between fetal head and symphysis pubis in obstructed labor Ischemic necrosis infection sloughing fistula develops in 3-5 days of delivery. Traumatic- caused during instrumental vaginal delivery as forceps application or destructive operation (craniotomy) or may occur during cesarean or cesarean hysterectomy. […]
  • #16 Vesico vaginal fistula | PPT
    https://www.slideshare.net/slideshow/vesico-vaginal-fistula-242999654/242999654
    1. PATHOPHYSIOLOGY TISSUE DAMAGE AND NECROSIS AFTER INJURY CAUSES INFLAMMATION PROCESS OF CELL REGENERATION BEGINS ANGIO-GENESIS STARTS FIRST FIBROBLASTS PROLIFERATE AND SUBSEQUENTLY SYNTHESIZE AND DEPOSIT EXTRACELLULAR MATRIX, PARTICULARLY COLLAGEN (FIBROSIS PHASE) COLLAGEN DEPOSITION PEAKS APPROXIMATELY 7 DAYS AFTER INJURY AND CONTINUES FOR SEVERAL WEEKS SUBSEQUENTLY SCAR FORMATION AND ORGANIZATION (REMODELLING) AUGMENTS WOUND STRENGTH ANY DISRUPTION IN THIS SEQUENCE EVENTUALLY MAY CREATE A FISTULA 1-3 WEEKS AFTER TISSUE INJURY IS MOST VULNERABLE TIME TO ALTERATION IN HEALING ENVIRONMENT AS HYPOXIA, ISCHEMIA, MALNUTRITION, RADIATION OR CHEMOTHERAPY. EDGES OF WOUND EPITHELIALIZE TO FORM CHRONIC FISTULOUS TRACT […] […] 11. Etio-pathogenesis In developing countries, most common (70 %) cause is obstetrical due to ischemia or trauma. Ischemia result from- Prolonged compression on the bladder base between fetal head and symphysis pubis in obstructed labor Ischemic necrosis infection sloughing fistula develops in 3-5 days of delivery. Traumatic- caused during instrumental vaginal delivery as forceps application or destructive operation (craniotomy) or may occur during cesarean or cesarean hysterectomy. […]
  • #17
    https://www.ics.org/committees/developingworld/publicawareness/obstetricfistulaanintroduction
    Obstetric fistula is a wholly preventable condition, provided that appropriate medical and obstetric facilities including emergency caesarean section are available. […] In developing countries, obstetric fistula is the result of prolonged or obstructed (blocked) labour, often lasting several days, when the unborn baby cannot pass through the pelvis. The pressure of the babys head for an abnormally long time on the blood vessels supplying the tissue of the vagina, bladder, urethra and rectum cuts off the supply of oxygen (ischaemia) and leads to the death of the affected tissue (necrosis). […] The immense number of obstetric fistulas occurring in developing countries is of great concern, particularly since they are preventable if the right facilities are in place. Since surgical repair is not always successful even in the very best hands, prevention is paramount.
  • #18 Obstetric fistula – Wikipedia
    https://en.wikipedia.org/wiki/Obstetric_fistula
    Obstetric fistula is a medical condition in which a hole develops in the birth canal as a result of childbirth. This can be between the vagina and rectum, ureter, or bladder. It can result in incontinence of urine or feces. Complications may include depression, infertility, and social isolation. […] The underlying mechanism is poor blood flow to the affected area for a prolonged period of time. […] Over the course of the three to five days of labor, the unborn child presses against the mother’s vagina very tightly, cutting off blood flow to the surrounding tissues between the vagina and the rectum and between the vagina and the bladder, causing the tissues to disintegrate and rot away. […] Obstetric fistulae can also be caused by poorly performed abortions, and pelvic fracture, cancer, or radiation therapy targeted at the pelvic area, inflammatory bowel disease (such as Crohn’s disease and ulcerative colitis). Other potential causes for the development of obstetric fistulae are sexual abuse and rape, especially in conflict/postconflict areas, and other trauma, such as surgical trauma. […] In the developed world, such as the US, the primary cause of obstetric fistulae, particularly rectovaginal fistulae, is the use of episiotomy and forceps.
  • #19 Vesicovaginal and Ureterovaginal Fistula: Practice Essentials, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/452934-overview
    Unrecognized bladder injury during a difficult hysterectomy or cesarean delivery may result in vesicovaginal fistula formation. Most vesicovaginal fistulae occur when dissection of the bladder during the mobilization of the bladder flap causes devascularization or an unrecognized tear of the posterior bladder wall. Alternatively, if the vaginal cuff suture was unknowingly incorporated into the bladder, this can result in tissue ischemia, necrosis, and subsequent fistula formation. […] The ureter may become injured during the dissection around the infundibulopelvic ligament or ligation of the uterine vessels. Unexpected pelvic hemorrhage may obscure the surgeon’s vision and result in ureteral injury that manifests as delayed ureterovaginal fistula. Uncommonly, this can also occur in the setting of an unrecognized duplicated ureter.
  • #20 Vesicovaginal and Ureterovaginal Fistula: Practice Essentials, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/452934-overview
    Fistulae resulting from vaginal birth occur during difficult or prolonged labor. The head of the fetus compresses the trigone or the bladder neck against the anterior arch of the pubic symphysis. This may result in tissue ischemia, necrosis, and eventual fistula formation. Currently, this is rare in the United States; however, it remains common throughout much of the world.
  • #21 Vesicovaginal and Ureterovaginal Fistula: Practice Essentials, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/452934-overview
    Unrecognized bladder injury during a difficult hysterectomy or cesarean delivery may result in vesicovaginal fistula formation. Most vesicovaginal fistulae occur when dissection of the bladder during the mobilization of the bladder flap causes devascularization or an unrecognized tear of the posterior bladder wall. Alternatively, if the vaginal cuff suture was unknowingly incorporated into the bladder, this can result in tissue ischemia, necrosis, and subsequent fistula formation. […] The ureter may become injured during the dissection around the infundibulopelvic ligament or ligation of the uterine vessels. Unexpected pelvic hemorrhage may obscure the surgeon’s vision and result in ureteral injury that manifests as delayed ureterovaginal fistula. Uncommonly, this can also occur in the setting of an unrecognized duplicated ureter.
  • #22 Rectovaginal Fistula: Practice Essentials, Anatomy, Pathophysiology
    https://emedicine.medscape.com/article/193277-overview
    The use of radiation to treat pelvic malignancies may give rise to RVFs. Fistulas that occur during such therapy usually result from tumor regression. […] A variety of infectious conditions can produce RVF. The most common are perirectal abscess/fistula and diverticulitis. Less commonly, tuberculosis, lymphogranuloma venereum, and Bartholin gland abscess can cause RVFs.
  • #23
    https://link.springer.com/article/10.1007/BF01658140
    The radiation-induced vaginal fistula is an extremely difficult rehabilitative challenge to the surgeon. Historically there has been a sense of frustration about prospects for success with these defects and many patients have been managed by either permanent colostomy or permanent urinary diversion. This report reviews a personal experience of 25 radiation-induced vaginal fistulas in 22 patients utilizing the Martius bulbocavernosus-labial fat flap technique. Successful closure was accomplished in 84.2% of the rectovaginal fistulas and 50% of the vesicovaginal fistulas. Only 1 patient required a second surgical effort for successful closure. There was no surgical mortality and no significant surgical morbidity. No patient with a rectovaginal fistula closure required subsequent colostomy for stricture. These results, coupled with the relative simplicity of the procedure, allow us to recommend this technique as firstline therapy for these difficult management problems. The majority of patients will be rewarded with successful rehabilitation.
  • #24 Elucidating vaginal fistulas on CT and MRI | Insights into Imaging | Full Text
    https://insightsimaging.springeropen.com/articles/10.1186/s13244-019-0812-9
    Vaginal fistulas (VF) represent abnormal communications between the vagina and either the distal portion of the digestive system or the lower urinary tract, but lack an accepted classification and standardised terminology. […] The spectrum of causes encompasses congenital and developmental abnormalities, inflammatory diseases, infections, tumours, sexual and obstetric trauma, irradiation and post-surgical injuries. […] Regardless of the underlying disorder, all VF result in substantial morbidity and severely impair the patients quality of life. […] Entero-VF may involve the sigmoid colon (colo-VF), rectum (recto-VF) or anus (ano-VF). Their underlying causes and mechanisms are summarised in Table 1. […] In developing countries, VF are still common and almost invariably secondary to obstructed labour. Conversely, despite advancements in open and laparoscopic surgical techniques, in the Western world, over 90% of all urinary VF now develop as iatrogenic complications of irradiation or surgical injury to either distal ureter or bladder. […] The ideal cross-sectional techniques depend on the anatomic site and affected organ. With appropriate acquisition and focused interpretation, state-of-the art CT and MRI provide optimal visualisation of entero- and urinary VF that is crucial for correct therapeutic choice and surgical planning.
  • #25 Rectovaginal Fistula: Practice Essentials, Anatomy, Pathophysiology
    https://emedicine.medscape.com/article/193277-overview
    Several traumatic mechanisms for the development of RVF exist. Perineal lacerations during childbirth, especially those due to episioproctotomy, predispose patients to RVFs. […] Failure to recognize and correctly repair perineal lacerations, or secondary infection of perineal lacerations, further increases the chance of RVF. Prolonged labor with pressure on the rectovaginal septum can produce necrosis and result in RVF. […] Vaginal or rectal operative procedures, especially those performed near the dentate line, may cause RVFs. Stapled hemorrhoidopexy, STARR (stapled transanal rectal resection), and TRANSTAR (transanal stapler-assisted resection) have been increasingly associated with RVFs. […] Crohn disease and, less often, ulcerative colitis have been associated with RVFs. The fistula may arise primarily or, more often, in relation to a perirectal abscess or fistula, manifesting as complicated perianal sepsis.
  • #26 Rectovaginal Fistula: Practice Essentials, Anatomy, Pathophysiology
    https://emedicine.medscape.com/article/193277-overview
    The use of radiation to treat pelvic malignancies may give rise to RVFs. Fistulas that occur during such therapy usually result from tumor regression. […] A variety of infectious conditions can produce RVF. The most common are perirectal abscess/fistula and diverticulitis. Less commonly, tuberculosis, lymphogranuloma venereum, and Bartholin gland abscess can cause RVFs.
  • #27 Rectovaginal Fistula – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK535350/
    A fistula is an abnormal connection between 2 epithelial surfaces. This is a general definition that applies to most of the known fistula but not all of them. The general description differentiates fistulae from sinuses, abscesses, and other forms of luminal tracts or extra-luminal collections. Fistula connects two surfaces or lumens. It begins on the offending side and makes its way to an adjacent lumen or surface. It follows the easiest and shortest path to the adjacent organ. Recto-vaginal fistula starts from the rectum and extends to the vagina. This activity describes the pathophysiology, etiology, and presentation of rectovaginal fistula and highlights the role of the interprofessional team in its management. […] Like other fistulae, RVF is a result of a complication of an underlying disease, surgical procedure, or injury. A good understanding of the pathophysiological process helps to assess better, manage, and prevent fistulae. Loss of wall integrity with ongoing inflammatory, infectious, or neoplastic processes at the rectal or vaginal wall can lead to erosion to the adjacent tissue or organ and establish an abnormal fistulous connection. When the initial process is reversible or curable, such as diverticulitis, fistulae have a better chance to resolve.
  • #28 Vaginal fistula – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/vaginal-fistulas/symptoms-causes/syc-20355762
    Vaginal fistulas can form after childbirth or after an injury, a surgery, an infection or radiation treatment. […] Surgery complications. Surgeries that involve the vaginal wall, anus or rectum can lead to vaginal fistulas. So can surgery on the area between the vagina and anus, called the perineum. Fistulas can form for reasons such as injuries during surgery and infections after surgery. […] Childbirth injuries. A vaginal fistula could stem from tearing that sometimes happens when a baby’s head comes through the opening of the vagina. Or a fistula might form due to an infection of a surgical cut made between the vagina and the anus to help deliver a baby. […] Certain cancers and radiation therapy. Cancer of the anus, rectum, vagina or cervix can lead to a vaginal fistula. So can damage from radiation therapy for the treatment of cancer in the pelvic area.
  • #29 Colorectal-Vaginal Fistulas: Imaging and Novel Interventional Treatment Modalities
    https://www.mdpi.com/2077-0383/7/4/87
    Vaginal fistulas account for some of the most distressing symptoms seen by clinicians today. The etiology of vaginal fistulas includes obstetrical complications, inflammatory bowel disease, post-surgical causes, pelvic malignancies, trauma, infection, congenital conditions, and radiation effects. […] The prevalence of fistulas is poorly delineated in the literature, and varies widely in regards to etiology. Worldwide, the most common types of fistulas are vesicovaginal and rectovaginal due to obstetric causes. […] This is thought to be a result of tissue necrosis in the pelvis, caused by tissue entrapment between fetal parts and the bony pelvis. […] In industrialized countries, vaginal fistulas are more commonly iatrogenic, resulting from surgical intervention or radiation therapy. […] The most common iatrogenic cause is surgery following obstetric complications or gynecologic procedures, predominantly hysterectomies, with the most common type thought to be vesicovaginal fistulas.
  • #30 Colorectal-Vaginal Fistulas: Imaging and Novel Interventional Treatment Modalities
    https://www.mdpi.com/2077-0383/7/4/87
    Vaginal fistulas account for some of the most distressing symptoms seen by clinicians today. The etiology of vaginal fistulas includes obstetrical complications, inflammatory bowel disease, post-surgical causes, pelvic malignancies, trauma, infection, congenital conditions, and radiation effects. […] The prevalence of fistulas is poorly delineated in the literature, and varies widely in regards to etiology. Worldwide, the most common types of fistulas are vesicovaginal and rectovaginal due to obstetric causes. […] This is thought to be a result of tissue necrosis in the pelvis, caused by tissue entrapment between fetal parts and the bony pelvis. […] In industrialized countries, vaginal fistulas are more commonly iatrogenic, resulting from surgical intervention or radiation therapy. […] The most common iatrogenic cause is surgery following obstetric complications or gynecologic procedures, predominantly hysterectomies, with the most common type thought to be vesicovaginal fistulas.
  • #31 Colorectal-Vaginal Fistulas: Imaging and Novel Interventional Treatment Modalities
    https://www.mdpi.com/2077-0383/7/4/87
    Other risk factors include smoking, diabetes, obesity, and a previous history of irradiation. […] In the setting of pelvic malignancies, tumors may cause local tissue destruction resulting in fistula formation. […] Radiation can lead to fistula formation due to obliterative endarteritis and chronic ischemia. […] The accurate diagnosis of vaginal fistulas begins with a detailed history and careful physical examination of the patient. […] Currently, the preferable modalities of choice for pelvic fistula evaluation are magnetic resonance (MR) and multidetector computed tomography (CT) for patients unable to get an MRI, with the goal of imaging being to provide the clinician with a specific anatomic site and fistula course. […] Once diagnosis has been achieved, the management of patients with vaginal fistulas is as much determined by their etiology as by physical factors, including the size, location, and complexity of the tract.
  • #32
    https://www.ics.org/committees/developingworld/publicawareness/obstetricfistulaanintroduction
    The primary risk factors for obstetric fistula are lack of access to medical facilities, obstetric care and emergency caesarean section delivery; lack of adequately trained, skilled medical staff; lack of medical supplies and equipment. […] Other contributory risk factors include poverty and malnutrition leading to stunted growth that could make women more susceptible to obstructed labour.
  • #33 Surgeons’ perspectives for a future obstetric fistula classification system: exploring the key parameters | Published in Journal of Global Health Reports
    https://www.joghr.org/article/77981-surgeons-perspectives-for-a-future-obstetric-fistula-classification-system-exploring-the-key-parameters
    Obstetric fistulas are aberrant connections between the genital tract, urinary tract, or gastrointestinal tract. The etiology of obstetric fistulas in resource-limited settings is most commonly pressure necrosis secondary to prolonged obstructed labor related to reduced access to health services, home delivery, and lack of infrastructure. In contrast, obstetric fistulas in high-resource settings are much less common and are most often due to surgical complications. […] The most critical factors that surgeons found necessary to include in an updated fistula classification system are the bladder size, degree of fibrosis of the vagina, degree of urethral damage, location of the fistula, urethral length, and whether the fistula is circumferential or not. […] Given the inconsistency between what experienced and expert surgeons deem to be important determinants for the classification of obstetric fistula and what is currently included in classification systems, we call for constructing a new, validated classification system.
  • #34 Vesicovaginal fistula | Radiology Reference Article | Radiopaedia.org
    https://radiopaedia.org/articles/vesicovaginal-fistula-2?lang=us
    Vesicovaginal fistulas are abnormal fistulous connections between the urinary bladder and vagina, resulting in an involuntary discharge of urine through the vagina. […] The tract is lined by squamous epithelium at the vaginal end and transitional epithelium at the bladder end, often with focal ulceration and fibrosis. […] There are a number of causes, including prolonged obstructed labor (most common in developing countries), surgery, e.g. hysterectomy (most common in developed countries), pelvic malignancy (e.g. bladder carcinoma, endometrial carcinoma), radiotherapy, uterine rupture. […] Other risk factors include trauma, pelvic inflammatory disease and diabetes.
  • #35 Vesicovaginal Fistula – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK564389/
    Vesicovaginal fistula is an anomalous communication between the bladder and vagina, resulting in continuous urine leakage through the vagina. This condition occurs most commonly after obstetrical and gynecological injury. […] A vesicovaginal fistula is an abnormal communication between the bladder and vagina, resulting in continuous urine leakage through the vagina. This condition occurs most commonly after obstetrical and gynecological injury. In the developed world, the most common cause of vesicovaginal fistula is gynecological surgery. In North America, bladder injury during a hysterectomy is the most common cause. […] The etiology of this condition varies and can be categorized into congenital or acquired. Acquired vesicovaginal fistula can be further divided into obstetric surgical, malignant, radiation, and miscellaneous categories. Congenital vesicovaginal fistula is very rare and typically associated with other urogenital malformations. Vesicovaginal fistula occurs most commonly after obstetrical and gynecological injury. In the developed world, the most common cause of vesicovaginal fistula is gynecological surgery. In North America, bladder injury during a hysterectomy is the most common cause. In developing countries, obstructed labor and the resulting pressure necrosis are the most common causes of vesicovaginal fistulas.
  • #36 Transvaginal repair of apical vesicovaginal fistula via vaginal natural orifice transluminal endoscopic surgery (V-NOTES): a modified surgical technique and its outcomes | Scientific Reports
    https://www.nature.com/articles/s41598-024-82366-y
    A vesicovaginal fistula (VVF) is defined as a pathological anatomical junction between the dorsal bladder wall and the anterior vagina. The pathophysiological mechanism for this abnormal anatomic connection is a necrosis of both organ walls as a result of ischemia. […] The timing of VVF repair depends on its etiology, comorbidities, and the anticipated approach for fistula repair. The transvaginal approach is more suitable for early repair, is less invasive, and is associated with a 90% or higher success rate. […] To treat patients with vesicovaginal fistulas, we developed a surgical technique called modified transvaginal natural orifice transluminal endoscopic surgery (V-NOTES). This method demonstrated positive efficacy and was successfully applied to male patients with urine incontinence. By enabling a thorough examination of the peritoneal cavity and providing continuous visual surveillance of the surrounding tissues, it would overcome the limitations of vaginal surgery.
  • #37 Vesicovaginal fistula | Radiology Reference Article | Radiopaedia.org
    https://radiopaedia.org/articles/vesicovaginal-fistula-2?lang=us
    Vesicovaginal fistulas are abnormal fistulous connections between the urinary bladder and vagina, resulting in an involuntary discharge of urine through the vagina. […] The tract is lined by squamous epithelium at the vaginal end and transitional epithelium at the bladder end, often with focal ulceration and fibrosis. […] There are a number of causes, including prolonged obstructed labor (most common in developing countries), surgery, e.g. hysterectomy (most common in developed countries), pelvic malignancy (e.g. bladder carcinoma, endometrial carcinoma), radiotherapy, uterine rupture. […] Other risk factors include trauma, pelvic inflammatory disease and diabetes.
  • #38 Rectovaginal Fistula – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK535350/
    A fistula is an abnormal connection between 2 epithelial surfaces. This is a general definition that applies to most of the known fistula but not all of them. The general description differentiates fistulae from sinuses, abscesses, and other forms of luminal tracts or extra-luminal collections. Fistula connects two surfaces or lumens. It begins on the offending side and makes its way to an adjacent lumen or surface. It follows the easiest and shortest path to the adjacent organ. Recto-vaginal fistula starts from the rectum and extends to the vagina. This activity describes the pathophysiology, etiology, and presentation of rectovaginal fistula and highlights the role of the interprofessional team in its management. […] Like other fistulae, RVF is a result of a complication of an underlying disease, surgical procedure, or injury. A good understanding of the pathophysiological process helps to assess better, manage, and prevent fistulae. Loss of wall integrity with ongoing inflammatory, infectious, or neoplastic processes at the rectal or vaginal wall can lead to erosion to the adjacent tissue or organ and establish an abnormal fistulous connection. When the initial process is reversible or curable, such as diverticulitis, fistulae have a better chance to resolve.
  • #39 Rectovaginal Fistula: Practice Essentials, Anatomy, Pathophysiology
    https://emedicine.medscape.com/article/193277-overview
    Several traumatic mechanisms for the development of RVF exist. Perineal lacerations during childbirth, especially those due to episioproctotomy, predispose patients to RVFs. […] Failure to recognize and correctly repair perineal lacerations, or secondary infection of perineal lacerations, further increases the chance of RVF. Prolonged labor with pressure on the rectovaginal septum can produce necrosis and result in RVF. […] Vaginal or rectal operative procedures, especially those performed near the dentate line, may cause RVFs. Stapled hemorrhoidopexy, STARR (stapled transanal rectal resection), and TRANSTAR (transanal stapler-assisted resection) have been increasingly associated with RVFs. […] Crohn disease and, less often, ulcerative colitis have been associated with RVFs. The fistula may arise primarily or, more often, in relation to a perirectal abscess or fistula, manifesting as complicated perianal sepsis.
  • #40 Rectovaginal and anovaginal fistulas – UpToDate
    https://www.uptodate.com/contents/rectovaginal-and-anovaginal-fistulas
    Anovaginal fistulas (AVFs) and rectovaginal fistulas (RVFs) most frequently result from obstetric trauma, especially in resource-limited countries where prolonged obstructed labor can lead to pressure necrosis of the rectovaginal septum. […] These fistulas can also occur following a failed repair of a third- or fourth-degree laceration of the perineum, from unrecognized injury at the time of vaginal delivery, and from episiotomy infection. Radiation damage and Crohn disease are two other important causes of RVFs. […] RVFs may also occur following difficult hysterectomies, especially those performed for severe endometriosis with involvement or obliteration of the posterior cul-de-sac (pouch of Douglas); from extension or rupture of perirectal, perianal, and, rarely, Bartholin’s abscesses; and from any surgical procedures involving the posterior vaginal wall, perineum, anus, or rectum. […] In older women, RVFs can occur as a result of diverticulitis, colon cancer, or fecal impaction. In addition, treatment options for pelvic organ prolapse such as pessaries and various mesh repair procedures have been associated with RVFs.
  • #41 Rectovaginal Fistula – Your Pelvic Floor
    https://www.yourpelvicfloor.org/conditions/rectovaginal-fistula/
    The majority of rectovaginal fistulas are caused by childbirth injury. Trauma related to operative vaginal deliveries such as forceps and vacuum deliveries, as well as third- and fourth-degree tears, increases the risk for rectovaginal fistulas to develop. […] Rectovaginal fistulas may involve disruption to the internal and external anal sphincter muscles. […] Irrespective of the approach, the fistula tract should be removed to allow normal tissue with a good blood supply to knit together. If the tissue near the fistula tract has poor blood supply, a graft or flap may be placed to promote healing. Grafts, or flaps, can come from a women’s own fat tissue or muscle that is placed over the repaired fistula tract. Other biologic grafts taken from animal tissue or human cadavers can also be used. The repair may also involve reconstruction of the internal and external anal sphincter muscles.
  • #42 Rectovaginal Fistula – Your Pelvic Floor
    https://www.yourpelvicfloor.org/conditions/rectovaginal-fistula/
    The majority of rectovaginal fistulas are caused by childbirth injury. Trauma related to operative vaginal deliveries such as forceps and vacuum deliveries, as well as third- and fourth-degree tears, increases the risk for rectovaginal fistulas to develop. […] Rectovaginal fistulas may involve disruption to the internal and external anal sphincter muscles. […] Irrespective of the approach, the fistula tract should be removed to allow normal tissue with a good blood supply to knit together. If the tissue near the fistula tract has poor blood supply, a graft or flap may be placed to promote healing. Grafts, or flaps, can come from a women’s own fat tissue or muscle that is placed over the repaired fistula tract. Other biologic grafts taken from animal tissue or human cadavers can also be used. The repair may also involve reconstruction of the internal and external anal sphincter muscles.
  • #43 Ureterovaginal fistula | Radiology Reference Article | Radiopaedia.org
    https://radiopaedia.org/articles/ureterovaginal-fistula-2?lang=us
    Ureterovaginal fistulae refer to abnormal communications between the lumina of the ureter(s) and the vagina. […] Ureterovaginal fistulae are commonly a complication of hysterectomy. Other less common causes include pelvic trauma and radiation therapy of pelvic neoplasms. […] They are often coexistent with vesicovaginal fistulas, which have a similar presentation. It is important to recognize and distinguish between these fistulae in such settings, as their management differs considerably.
  • #44 Vesicovaginal and Ureterovaginal Fistula: Practice Essentials, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/452934-overview
    Unrecognized bladder injury during a difficult hysterectomy or cesarean delivery may result in vesicovaginal fistula formation. Most vesicovaginal fistulae occur when dissection of the bladder during the mobilization of the bladder flap causes devascularization or an unrecognized tear of the posterior bladder wall. Alternatively, if the vaginal cuff suture was unknowingly incorporated into the bladder, this can result in tissue ischemia, necrosis, and subsequent fistula formation. […] The ureter may become injured during the dissection around the infundibulopelvic ligament or ligation of the uterine vessels. Unexpected pelvic hemorrhage may obscure the surgeon’s vision and result in ureteral injury that manifests as delayed ureterovaginal fistula. Uncommonly, this can also occur in the setting of an unrecognized duplicated ureter.
  • #45 Ureterovaginal fistula | Radiology Reference Article | Radiopaedia.org
    https://radiopaedia.org/articles/ureterovaginal-fistula-2?lang=us
    Ureterovaginal fistulae refer to abnormal communications between the lumina of the ureter(s) and the vagina. […] Ureterovaginal fistulae are commonly a complication of hysterectomy. Other less common causes include pelvic trauma and radiation therapy of pelvic neoplasms. […] They are often coexistent with vesicovaginal fistulas, which have a similar presentation. It is important to recognize and distinguish between these fistulae in such settings, as their management differs considerably.
  • #46 Transvaginal repair of apical vesicovaginal fistula via vaginal natural orifice transluminal endoscopic surgery (V-NOTES): a modified surgical technique and its outcomes | Scientific Reports
    https://www.nature.com/articles/s41598-024-82366-y
    By enabling thorough examination of the peritoneal cavity and ongoing visual control of the surrounding tissues, V-NOTES can get over the limitations of vaginal surgery. By utilizing the advantages of endoscopic surgery, the V-NOTES technique avoids the technical and surgical difficulties that come with traditional vaginal surgery. Furthermore, V-NOTES addresses problems associated with trocar-related complications and abdominal wall incisions by using low-cost, reusable, and handcrafted standard laparoscopic equipment. Fistulae healing in this way will have an 82-100% success rate.
  • #47 James Marion Sims’s Treatment of Vesico-Vaginal Fistula | Embryo Project Encyclopedia
    https://embryo.asu.edu/pages/james-marion-simss-treatment-vesico-vaginal-fistula
    James Marion Sims developed a treatment for vesico-vaginal fistulas in Montgomery, Alabama in the 1840s. Vesico-vaginal fistulas consist of a breach of the wall separating the vagina and neighboring bladder, connecting the two cavities. The causes of vesico-vaginal fistulas are numerous, but many result from long, traumatic childbirth in which prolonged labor puts too much pressure on the vaginal wall. […] Tissue death, scar formation, and shedding of the vaginal walls can also occur in patients with vesico-vaginal fistulas. […] Inflammation, however, still regularly occurred when Sims used unsterilized silk to suture the wounds. […] Sims realized that he might use metal sutures as a possible substitute for silk ones. […] Silver’s aseptic and anti-inflammatory properties provided Sims with a wire stitch that held together the edges of fistulas without enabling infections. […] Sims’s application of metal sutures, specifically silver sutures, changed the way doctors treated vesico-vaginal fistulas.
  • #48 Vesico vaginal fistula | PPT
    https://www.slideshare.net/slideshow/vesico-vaginal-fistula-242999654/242999654
    13. Gynaecological causes are more common in developed countries. In post-operative cases, rate of fistula formation with procedure type and its indication, as highest chance with radical hysterectomy for cervical cancer and lowest with vaginal hysterectomy for prolapse. Risk factors include cancer stage, intra-operative bladder injury, diabetes and post-operative surgical site infection. Vaginal cancer shows a high likelihood of fistula formation (both vesicovaginal and rectovaginal) with no association with radiotherapy. […] […] 42. Surgical management Indication when conservative therapy fails or patient is not a candidate for conservative therapy. Principles of surgery- 1. Correct pre-operative assessment and preparation 2. Timely repair 3. Perfect asepsis and good exposure of fistula 4. Excision (minimal) of scar tissue at margins 5. Presence of healthy vascular margin 6. Mobilization of bladder wall from the vagina 7. Tension free repair in 2 layers 8. Fine suture material 9. Minimal use of electrocautery 10. Post-operative bladder drainage […]
  • #49
    https://link.springer.com/article/10.1007/BF01658140
    The radiation-induced vaginal fistula is an extremely difficult rehabilitative challenge to the surgeon. Historically there has been a sense of frustration about prospects for success with these defects and many patients have been managed by either permanent colostomy or permanent urinary diversion. This report reviews a personal experience of 25 radiation-induced vaginal fistulas in 22 patients utilizing the Martius bulbocavernosus-labial fat flap technique. Successful closure was accomplished in 84.2% of the rectovaginal fistulas and 50% of the vesicovaginal fistulas. Only 1 patient required a second surgical effort for successful closure. There was no surgical mortality and no significant surgical morbidity. No patient with a rectovaginal fistula closure required subsequent colostomy for stricture. These results, coupled with the relative simplicity of the procedure, allow us to recommend this technique as firstline therapy for these difficult management problems. The majority of patients will be rewarded with successful rehabilitation.
  • #50
    https://link.springer.com/article/10.1007/BF01658140
    The radiation-induced vaginal fistula is an extremely difficult rehabilitative challenge to the surgeon. Historically there has been a sense of frustration about prospects for success with these defects and many patients have been managed by either permanent colostomy or permanent urinary diversion. This report reviews a personal experience of 25 radiation-induced vaginal fistulas in 22 patients utilizing the Martius bulbocavernosus-labial fat flap technique. Successful closure was accomplished in 84.2% of the rectovaginal fistulas and 50% of the vesicovaginal fistulas. Only 1 patient required a second surgical effort for successful closure. There was no surgical mortality and no significant surgical morbidity. No patient with a rectovaginal fistula closure required subsequent colostomy for stricture. These results, coupled with the relative simplicity of the procedure, allow us to recommend this technique as firstline therapy for these difficult management problems. The majority of patients will be rewarded with successful rehabilitation.
  • #51 Surgeons’ perspectives for a future obstetric fistula classification system: exploring the key parameters | Published in Journal of Global Health Reports
    https://www.joghr.org/article/77981-surgeons-perspectives-for-a-future-obstetric-fistula-classification-system-exploring-the-key-parameters
    Obstetric fistulas are aberrant connections between the genital tract, urinary tract, or gastrointestinal tract. The etiology of obstetric fistulas in resource-limited settings is most commonly pressure necrosis secondary to prolonged obstructed labor related to reduced access to health services, home delivery, and lack of infrastructure. In contrast, obstetric fistulas in high-resource settings are much less common and are most often due to surgical complications. […] The most critical factors that surgeons found necessary to include in an updated fistula classification system are the bladder size, degree of fibrosis of the vagina, degree of urethral damage, location of the fistula, urethral length, and whether the fistula is circumferential or not. […] Given the inconsistency between what experienced and expert surgeons deem to be important determinants for the classification of obstetric fistula and what is currently included in classification systems, we call for constructing a new, validated classification system.
  • #52 Surgeons’ perspectives for a future obstetric fistula classification system: exploring the key parameters | Published in Journal of Global Health Reports
    https://www.joghr.org/article/77981-surgeons-perspectives-for-a-future-obstetric-fistula-classification-system-exploring-the-key-parameters
    Upon survey of experienced and expert fistula surgeons, the following factors were deemed as most important for a classification scheme: bladder size, degree of fibrosis of the vagina, degree of urethral damage, location of the fistula, urethral length, and whether the fistula is circumferential or not. […] This study, therefore, aims to assess which factors are the most important to include in a future classification scheme.
  • #53 Laparoscopic Vesicovaginal Fistula Repair
    https://www.laparoscopyhospital.com/streamlecture/index.php?pid=44&p=&cat_id=&search=
    Overall, laparoscopic vesicovaginal fistula repair is a safe and effective option for treating this condition. […] It is important to note that not all vesicovaginal fistulas are amenable to laparoscopic repair, and the decision to use this approach will depend on the specific characteristics of the fistula and the experience of the surgeon. […] Patients should also be aware that there is a learning curve associated with laparoscopic vesicovaginal fistula repair, and the success of the procedure may depend on the experience and skill of the surgeon.
  • #54
    https://www.ijsurgery.com/index.php/isj/article/view/3752
    Vesicovaginal Fistula (VVF), an abnormal communication between the urinary bladder and vagina, is one of the most distressing and embarrassing health problems for the females. […] Failures in present study could be attributable to extensive fibrosis especially in prior failed repairs and in those with prolonged duration of symptoms. […] The principles of fistula repair, experience of surgeon and case selection remain important determinants of outcome.
  • #55 Outcome of urethral reconstruction among vesico-vaginal fistula patients: a cross-sectional study | African Journal of Urology | Full Text
    https://afju.springeropen.com/articles/10.1186/s12301-021-00147-9
    The success of a urinary fistula repair is defined based on successful closure and restoration of urinary continence. […] Stress incontinence occurs in about 10% of OF; it is associated with large fistula. […] The urethral involvement in obstetric fistula is a known risk factor for residual incontinence following fistula repair and one of the leading causes as demonstrated by previous studies. […] Factors which independently predict residual incontinence after repair include urethral involvement, small bladder, vaginal scarring and size of the fistula. […] The main complication documented in this study was residual incontinence despite successful closurestress incontinence.
  • #56
    https://www.ijsurgery.com/index.php/isj/article/view/3752
    Vesicovaginal Fistula (VVF), an abnormal communication between the urinary bladder and vagina, is one of the most distressing and embarrassing health problems for the females. […] Failures in present study could be attributable to extensive fibrosis especially in prior failed repairs and in those with prolonged duration of symptoms. […] The principles of fistula repair, experience of surgeon and case selection remain important determinants of outcome.
  • #57 Vesicovaginal Fistula – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK564389/
    The primary complication of vesicovaginal fistula surgery is recurrent fistula formation. Urinary frequency and urgency most commonly arise in the acute perioperative setting. Urgency and stress urinary incontinence are recognized as long-term complications of vesicovaginal repair. In obstetric causes for fistula formation where the sphincter mechanism is injured, stress urinary incontinence is common. […] The majority of vesicovaginal fistula require definitive surgical management; however, some can be successfully managed conservatively. Despite an optimistic prognosis for patients receiving proper treatment, efforts should be focused on the prevention of vesicovaginal formation.
  • #58 Outcome of urethral reconstruction among vesico-vaginal fistula patients: a cross-sectional study | African Journal of Urology | Full Text
    https://afju.springeropen.com/articles/10.1186/s12301-021-00147-9
    The success of a urinary fistula repair is defined based on successful closure and restoration of urinary continence. […] Stress incontinence occurs in about 10% of OF; it is associated with large fistula. […] The urethral involvement in obstetric fistula is a known risk factor for residual incontinence following fistula repair and one of the leading causes as demonstrated by previous studies. […] Factors which independently predict residual incontinence after repair include urethral involvement, small bladder, vaginal scarring and size of the fistula. […] The main complication documented in this study was residual incontinence despite successful closurestress incontinence.
  • #59 Vesico vaginal fistula | PPT
    https://www.slideshare.net/slideshow/vesico-vaginal-fistula-242999654/242999654
    13. Gynaecological causes are more common in developed countries. In post-operative cases, rate of fistula formation with procedure type and its indication, as highest chance with radical hysterectomy for cervical cancer and lowest with vaginal hysterectomy for prolapse. Risk factors include cancer stage, intra-operative bladder injury, diabetes and post-operative surgical site infection. Vaginal cancer shows a high likelihood of fistula formation (both vesicovaginal and rectovaginal) with no association with radiotherapy. […] […] 42. Surgical management Indication when conservative therapy fails or patient is not a candidate for conservative therapy. Principles of surgery- 1. Correct pre-operative assessment and preparation 2. Timely repair 3. Perfect asepsis and good exposure of fistula 4. Excision (minimal) of scar tissue at margins 5. Presence of healthy vascular margin 6. Mobilization of bladder wall from the vagina 7. Tension free repair in 2 layers 8. Fine suture material 9. Minimal use of electrocautery 10. Post-operative bladder drainage […]
  • #60 Outcome of urethral reconstruction among vesico-vaginal fistula patients: a cross-sectional study | African Journal of Urology | Full Text
    https://afju.springeropen.com/articles/10.1186/s12301-021-00147-9
    The success of a urinary fistula repair is defined based on successful closure and restoration of urinary continence. […] Stress incontinence occurs in about 10% of OF; it is associated with large fistula. […] The urethral involvement in obstetric fistula is a known risk factor for residual incontinence following fistula repair and one of the leading causes as demonstrated by previous studies. […] Factors which independently predict residual incontinence after repair include urethral involvement, small bladder, vaginal scarring and size of the fistula. […] The main complication documented in this study was residual incontinence despite successful closurestress incontinence.
  • #61 Outcome of urethral reconstruction among vesico-vaginal fistula patients: a cross-sectional study | African Journal of Urology | Full Text
    https://afju.springeropen.com/articles/10.1186/s12301-021-00147-9
    The success of a urinary fistula repair is defined based on successful closure and restoration of urinary continence. […] Stress incontinence occurs in about 10% of OF; it is associated with large fistula. […] The urethral involvement in obstetric fistula is a known risk factor for residual incontinence following fistula repair and one of the leading causes as demonstrated by previous studies. […] Factors which independently predict residual incontinence after repair include urethral involvement, small bladder, vaginal scarring and size of the fistula. […] The main complication documented in this study was residual incontinence despite successful closurestress incontinence.
  • #62 Laparoscopic Vesicovaginal Fistula Repair
    https://www.laparoscopyhospital.com/streamlecture/index.php?pid=44&p=&cat_id=&search=
    Laparoscopic Vesicovaginal Fistula Repair is a minimally invasive surgical procedure used to repair a vesicovaginal fistula. A vesicovaginal fistula is an abnormal connection between the bladder and the vagina, which can lead to the leakage of urine into the vagina. This can be a distressing condition for women, and can cause discomfort, embarrassment, and social isolation. […] The laparoscopic approach to repairing a vesicovaginal fistula involves the use of small incisions in the abdomen, through which a laparoscope (a thin, flexible tube with a camera and light at the end) and other surgical instruments are inserted. This allows the surgeon to visualize the area and perform the repair without making a large incision. […] The advantages of laparoscopic vesicovaginal fistula repair include a shorter hospital stay, reduced pain and scarring, and a quicker recovery time compared to traditional open surgery.
  • #63 Transvaginal repair of apical vesicovaginal fistula via vaginal natural orifice transluminal endoscopic surgery (V-NOTES): a modified surgical technique and its outcomes | Scientific Reports
    https://www.nature.com/articles/s41598-024-82366-y
    A vesicovaginal fistula (VVF) is defined as a pathological anatomical junction between the dorsal bladder wall and the anterior vagina. The pathophysiological mechanism for this abnormal anatomic connection is a necrosis of both organ walls as a result of ischemia. […] The timing of VVF repair depends on its etiology, comorbidities, and the anticipated approach for fistula repair. The transvaginal approach is more suitable for early repair, is less invasive, and is associated with a 90% or higher success rate. […] To treat patients with vesicovaginal fistulas, we developed a surgical technique called modified transvaginal natural orifice transluminal endoscopic surgery (V-NOTES). This method demonstrated positive efficacy and was successfully applied to male patients with urine incontinence. By enabling a thorough examination of the peritoneal cavity and providing continuous visual surveillance of the surrounding tissues, it would overcome the limitations of vaginal surgery.
  • #64 Vaginal fistulas – Urogynecology & Pelvic Reconstructive Surgery | Northwell Health
    https://www.northwell.edu/obstetrics-and-gynecology/urogynecology-pelvic-reconstructive-surgery/conditions/vaginal-fistulas
    A vaginal fistula is an abnormal opening between the vagina and another organ. A vesicovaginal fistula is an abnormal connection between the bladder and the vagina; a rectovaginal fistula is an abnormal opening between the rectum and the vagina; an enterovaginal fistula is an abnormal opening between the small bowels and the vagina. These openings may result in incontinence. […] The most common cause of vaginal fistulas is prolonged labor. Fistulas can also be caused by urologic or pelvic surgery, an infection or cancer. Sometimes, conditions like Crohns disease or diverticulitis can lead to a vaginal fistula. Accidents and traumatic injuries can also lead to a vaginal fistula. […] Vaginal fistulas are typically repaired surgically through the vagina. This procedure has the lowest risk of complication. However, depending on the location and complexity of the fistula, it may be necessary to perform the surgery through the abdomen. Repairing fistula through the abdomen can be done via robotic surgery, which typically minimizes the size of the incision and the amount of pain for the patient. […] If a patient presents with a clean fistula and is in good health, the success rate of fistula surgery is high. The procedure, like any surgery, does carry the risk of bleeding, infection and damage to surrounding organs.
  • #65 Transvaginal repair of apical vesicovaginal fistula via vaginal natural orifice transluminal endoscopic surgery (V-NOTES): a modified surgical technique and its outcomes | Scientific Reports
    https://www.nature.com/articles/s41598-024-82366-y
    A vesicovaginal fistula (VVF) is defined as a pathological anatomical junction between the dorsal bladder wall and the anterior vagina. The pathophysiological mechanism for this abnormal anatomic connection is a necrosis of both organ walls as a result of ischemia. […] The timing of VVF repair depends on its etiology, comorbidities, and the anticipated approach for fistula repair. The transvaginal approach is more suitable for early repair, is less invasive, and is associated with a 90% or higher success rate. […] To treat patients with vesicovaginal fistulas, we developed a surgical technique called modified transvaginal natural orifice transluminal endoscopic surgery (V-NOTES). This method demonstrated positive efficacy and was successfully applied to male patients with urine incontinence. By enabling a thorough examination of the peritoneal cavity and providing continuous visual surveillance of the surrounding tissues, it would overcome the limitations of vaginal surgery.
  • #66 Transvaginal repair of apical vesicovaginal fistula via vaginal natural orifice transluminal endoscopic surgery (V-NOTES): a modified surgical technique and its outcomes | Scientific Reports
    https://www.nature.com/articles/s41598-024-82366-y
    By enabling thorough examination of the peritoneal cavity and ongoing visual control of the surrounding tissues, V-NOTES can get over the limitations of vaginal surgery. By utilizing the advantages of endoscopic surgery, the V-NOTES technique avoids the technical and surgical difficulties that come with traditional vaginal surgery. Furthermore, V-NOTES addresses problems associated with trocar-related complications and abdominal wall incisions by using low-cost, reusable, and handcrafted standard laparoscopic equipment. Fistulae healing in this way will have an 82-100% success rate.
  • #67 Vesico vaginal fistula | PPT
    https://www.slideshare.net/slideshow/vesico-vaginal-fistula-242999654/242999654
    46. Various routes of fistula repair 1. Abdominal 2. Vaginal 3. Trans-peritoneal 4. Trans-vesical 5. Laparoscopic Indication for Trans-peritoneal and Trans-vesical approaches- A. Fistula located high up and vagina is narrow B. Fistula close to ureteric openings C. Previous failed repair D. Large or complex fistula E. When an interposition graft is needed.
  • #68 Vesico vaginal fistula | PPT
    https://www.slideshare.net/slideshow/vesico-vaginal-fistula-242999654/242999654
    46. Various routes of fistula repair 1. Abdominal 2. Vaginal 3. Trans-peritoneal 4. Trans-vesical 5. Laparoscopic Indication for Trans-peritoneal and Trans-vesical approaches- A. Fistula located high up and vagina is narrow B. Fistula close to ureteric openings C. Previous failed repair D. Large or complex fistula E. When an interposition graft is needed.
  • #69 Vesico vaginal fistula | PPT
    https://www.slideshare.net/slideshow/vesico-vaginal-fistula-242999654/242999654
    46. Various routes of fistula repair 1. Abdominal 2. Vaginal 3. Trans-peritoneal 4. Trans-vesical 5. Laparoscopic Indication for Trans-peritoneal and Trans-vesical approaches- A. Fistula located high up and vagina is narrow B. Fistula close to ureteric openings C. Previous failed repair D. Large or complex fistula E. When an interposition graft is needed.
  • #70 Transvaginal repair of apical vesicovaginal fistula via vaginal natural orifice transluminal endoscopic surgery (V-NOTES): a modified surgical technique and its outcomes | Scientific Reports
    https://www.nature.com/articles/s41598-024-82366-y
    By enabling thorough examination of the peritoneal cavity and ongoing visual control of the surrounding tissues, V-NOTES can get over the limitations of vaginal surgery. By utilizing the advantages of endoscopic surgery, the V-NOTES technique avoids the technical and surgical difficulties that come with traditional vaginal surgery. Furthermore, V-NOTES addresses problems associated with trocar-related complications and abdominal wall incisions by using low-cost, reusable, and handcrafted standard laparoscopic equipment. Fistulae healing in this way will have an 82-100% success rate.
  • #71 Vesico vaginal fistula | PPT
    https://www.slideshare.net/slideshow/vesico-vaginal-fistula-242999654/242999654
    13. Gynaecological causes are more common in developed countries. In post-operative cases, rate of fistula formation with procedure type and its indication, as highest chance with radical hysterectomy for cervical cancer and lowest with vaginal hysterectomy for prolapse. Risk factors include cancer stage, intra-operative bladder injury, diabetes and post-operative surgical site infection. Vaginal cancer shows a high likelihood of fistula formation (both vesicovaginal and rectovaginal) with no association with radiotherapy. […] […] 42. Surgical management Indication when conservative therapy fails or patient is not a candidate for conservative therapy. Principles of surgery- 1. Correct pre-operative assessment and preparation 2. Timely repair 3. Perfect asepsis and good exposure of fistula 4. Excision (minimal) of scar tissue at margins 5. Presence of healthy vascular margin 6. Mobilization of bladder wall from the vagina 7. Tension free repair in 2 layers 8. Fine suture material 9. Minimal use of electrocautery 10. Post-operative bladder drainage […]
  • #72 Rectovaginal Fistula – Your Pelvic Floor
    https://www.yourpelvicfloor.org/conditions/rectovaginal-fistula/
    The majority of rectovaginal fistulas are caused by childbirth injury. Trauma related to operative vaginal deliveries such as forceps and vacuum deliveries, as well as third- and fourth-degree tears, increases the risk for rectovaginal fistulas to develop. […] Rectovaginal fistulas may involve disruption to the internal and external anal sphincter muscles. […] Irrespective of the approach, the fistula tract should be removed to allow normal tissue with a good blood supply to knit together. If the tissue near the fistula tract has poor blood supply, a graft or flap may be placed to promote healing. Grafts, or flaps, can come from a women’s own fat tissue or muscle that is placed over the repaired fistula tract. Other biologic grafts taken from animal tissue or human cadavers can also be used. The repair may also involve reconstruction of the internal and external anal sphincter muscles.
  • #73 Vesico vaginal fistula | PPT
    https://www.slideshare.net/slideshow/vesico-vaginal-fistula-242999654/242999654
    13. Gynaecological causes are more common in developed countries. In post-operative cases, rate of fistula formation with procedure type and its indication, as highest chance with radical hysterectomy for cervical cancer and lowest with vaginal hysterectomy for prolapse. Risk factors include cancer stage, intra-operative bladder injury, diabetes and post-operative surgical site infection. Vaginal cancer shows a high likelihood of fistula formation (both vesicovaginal and rectovaginal) with no association with radiotherapy. […] […] 42. Surgical management Indication when conservative therapy fails or patient is not a candidate for conservative therapy. Principles of surgery- 1. Correct pre-operative assessment and preparation 2. Timely repair 3. Perfect asepsis and good exposure of fistula 4. Excision (minimal) of scar tissue at margins 5. Presence of healthy vascular margin 6. Mobilization of bladder wall from the vagina 7. Tension free repair in 2 layers 8. Fine suture material 9. Minimal use of electrocautery 10. Post-operative bladder drainage […]
  • #74 Rectovaginal Fistula – Your Pelvic Floor
    https://www.yourpelvicfloor.org/conditions/rectovaginal-fistula/
    The majority of rectovaginal fistulas are caused by childbirth injury. Trauma related to operative vaginal deliveries such as forceps and vacuum deliveries, as well as third- and fourth-degree tears, increases the risk for rectovaginal fistulas to develop. […] Rectovaginal fistulas may involve disruption to the internal and external anal sphincter muscles. […] Irrespective of the approach, the fistula tract should be removed to allow normal tissue with a good blood supply to knit together. If the tissue near the fistula tract has poor blood supply, a graft or flap may be placed to promote healing. Grafts, or flaps, can come from a women’s own fat tissue or muscle that is placed over the repaired fistula tract. Other biologic grafts taken from animal tissue or human cadavers can also be used. The repair may also involve reconstruction of the internal and external anal sphincter muscles.
  • #75 Vaginal Fistula: Types, Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/22079-vaginal-fistula
    Prolonged labor, trauma and pelvic surgeries can cause vaginal fistulas. These openings form when vaginal tissue dies, creating a hole between your vagina and organs in the urinary or digestive systems. A vaginal fistula is an abnormal connection or opening that develops between your vaginal wall and a nearby organ. Most often, they develop between your vagina and an organ in your urinary system or in your digestive system. They most often occur due to damage to your vaginal tissue from things like childbirth, surgery, injury or infection. A lack of blood supply to vaginal tissue causes the tissue to die or become damaged. A hole or fistula forms in the tissue where this damage occurs. These openings can develop in a few days or over several years. Causes of vaginal fistulas include: Prolonged labor during childbirth. Vaginal tears during childbirth or an episiotomy. Abdominal or pelvic surgery, including C-sections and hysterectomies. Cancer in your pelvic area, like cervical cancer or colorectal (colon) cancer. Inflammatory bowel diseases (IBD) like Crohns disease and ulcerative colitis. Colon infections like diverticulitis. Radiation therapy to the pelvic region. Trauma or injury. Surgical treatments for vaginal fistulas are highly successful. Most women experience a full recovery and no longer have symptoms.
  • #76 Vesicovaginal Fistula – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK564389/
    Vesicovaginal fistula is an anomalous communication between the bladder and vagina, resulting in continuous urine leakage through the vagina. This condition occurs most commonly after obstetrical and gynecological injury. […] A vesicovaginal fistula is an abnormal communication between the bladder and vagina, resulting in continuous urine leakage through the vagina. This condition occurs most commonly after obstetrical and gynecological injury. In the developed world, the most common cause of vesicovaginal fistula is gynecological surgery. In North America, bladder injury during a hysterectomy is the most common cause. […] The etiology of this condition varies and can be categorized into congenital or acquired. Acquired vesicovaginal fistula can be further divided into obstetric surgical, malignant, radiation, and miscellaneous categories. Congenital vesicovaginal fistula is very rare and typically associated with other urogenital malformations. Vesicovaginal fistula occurs most commonly after obstetrical and gynecological injury. In the developed world, the most common cause of vesicovaginal fistula is gynecological surgery. In North America, bladder injury during a hysterectomy is the most common cause. In developing countries, obstructed labor and the resulting pressure necrosis are the most common causes of vesicovaginal fistulas.
  • #77 Vaginal Fistula – Symptoms, Causes, Diagnosis and Treatment | CK Birla Hospital
    https://www.ckbhospital.com/blogs/vaginal-fistula-causes-symptoms-treatment/
    A fistula is defined as an unusual opening that develops between two organs of the body. A vaginal fistula is a tunnel-like opening that develops in the vagina wall. […] The vaginal fistula can lead to an abnormal interchange of fluids, gases, and substances between organs of different systems and the vagina. It can cause urine, gas, or stools to enter the vagina. […] A fistula in women is usually caused by tissue damage or inflammation. Traumatic vaginal fistulas occur due to damage to the tissue walls of the intestine, the urinary tract, or the vagina. This can happen due to surgical procedures/operations or prolonged labor during childbirth. […] An inflammatory fistula in women can form due to abscesses or cysts in the vagina or other traumas arising from disease or infection such as a tumor disease or inflammatory bowel disease like Crohns disease. […] Vaginal fistulas are caused by tissue damage to the vaginal walls. The kind of vaginal fistula depends on the organs involved. The treatment may involve surgery of the affected organs. You may also be prescribed medications or system-focused treatment based on what is causing the tissue damage.
  • #78 Colorectal-Vaginal Fistulas: Imaging and Novel Interventional Treatment Modalities
    https://www.mdpi.com/2077-0383/7/4/87
    Other risk factors include smoking, diabetes, obesity, and a previous history of irradiation. […] In the setting of pelvic malignancies, tumors may cause local tissue destruction resulting in fistula formation. […] Radiation can lead to fistula formation due to obliterative endarteritis and chronic ischemia. […] The accurate diagnosis of vaginal fistulas begins with a detailed history and careful physical examination of the patient. […] Currently, the preferable modalities of choice for pelvic fistula evaluation are magnetic resonance (MR) and multidetector computed tomography (CT) for patients unable to get an MRI, with the goal of imaging being to provide the clinician with a specific anatomic site and fistula course. […] Once diagnosis has been achieved, the management of patients with vaginal fistulas is as much determined by their etiology as by physical factors, including the size, location, and complexity of the tract.
  • #79 Vesicovaginal Fistula – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK564389/
    The primary complication of vesicovaginal fistula surgery is recurrent fistula formation. Urinary frequency and urgency most commonly arise in the acute perioperative setting. Urgency and stress urinary incontinence are recognized as long-term complications of vesicovaginal repair. In obstetric causes for fistula formation where the sphincter mechanism is injured, stress urinary incontinence is common. […] The majority of vesicovaginal fistula require definitive surgical management; however, some can be successfully managed conservatively. Despite an optimistic prognosis for patients receiving proper treatment, efforts should be focused on the prevention of vesicovaginal formation.
  • #80 Vaginal fistulas – Urogynecology & Pelvic Reconstructive Surgery | Northwell Health
    https://www.northwell.edu/obstetrics-and-gynecology/urogynecology-pelvic-reconstructive-surgery/conditions/vaginal-fistulas
    A vaginal fistula is an abnormal opening between the vagina and another organ. A vesicovaginal fistula is an abnormal connection between the bladder and the vagina; a rectovaginal fistula is an abnormal opening between the rectum and the vagina; an enterovaginal fistula is an abnormal opening between the small bowels and the vagina. These openings may result in incontinence. […] The most common cause of vaginal fistulas is prolonged labor. Fistulas can also be caused by urologic or pelvic surgery, an infection or cancer. Sometimes, conditions like Crohns disease or diverticulitis can lead to a vaginal fistula. Accidents and traumatic injuries can also lead to a vaginal fistula. […] Vaginal fistulas are typically repaired surgically through the vagina. This procedure has the lowest risk of complication. However, depending on the location and complexity of the fistula, it may be necessary to perform the surgery through the abdomen. Repairing fistula through the abdomen can be done via robotic surgery, which typically minimizes the size of the incision and the amount of pain for the patient. […] If a patient presents with a clean fistula and is in good health, the success rate of fistula surgery is high. The procedure, like any surgery, does carry the risk of bleeding, infection and damage to surrounding organs.