Materiały źródłowe

• #1 The epidemiology of premature ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5001986/

  Vast advances have occurred over the past decade with regards to understanding the epidemiology, pathophysiology and management of premature ejaculation (PE); however, we still have much to learn about this common sexual problem. […] As a standardized evidence-based definition of PE has only recently been established, the reported prevalence rates of PE prior to this definition have been difficult to interpret. […] In addition to the lack of a standardized definition and operational criteria, the method of recruitment for study participation and method of data collection have obviously contributed to the broad range of reported prevalence rates. […] While the absolute pathophysiology and true prevalence of PE remains unclear, developing a better understanding of the true prevalence of the disease will allow for the completion of more accurate analysis and treatment of the disease.

• #2 The epidemiology of premature ejaculation – Robert Saitz – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10575/html

  Vast advances have occurred over the past decade with regards to understanding the epidemiology, pathophysiology and management of premature ejaculation (PE); however, we still have much to learn about this common sexual problem. […] As a standardized evidence-based definition of PE has only recently been established, the reported prevalence rates of PE prior to this definition have been difficult to interpret. […] A large range of conflicting prevalence rates have been reported. […] In addition to the lack of a standardized definition and operational criteria, the method of recruitment for study participation and method of data collection have obviously contributed to the broad range of reported prevalence rates. […] While the absolute pathophysiology and true prevalence of PE remains unclear, developing a better understanding of the true prevalence of the disease will allow for the completion of more accurate analysis and treatment of the disease.

• #3

  https://journals.lww.com/co-urology/fulltext/2005/11000/epidemiology_of_premature_ejaculation.8.aspx

  Accumulating evidence suggests that premature ejaculation is the most common sexual symptom. This review focuses on the epidemiology of premature ejaculation from geographical and medical perspectives. […] Despite some methodological bias, discussed herein, a prevalence of more than 21% seems a realistic figure for premature ejaculation. […] Premature ejaculation is the most prevalent sexual dysfunction in every country.

• #4 Evolving Diagnosis and Management of Ejaculatory Disorders: A Focus on Premature Ejaculation

  https://www.medscape.org/viewarticle/508092

  I want to spend a few minutes on the epidemiology of PE. […] I mentioned before that it’s probably the most common form of male sexual dysfunction. It may even be more common than we think because there may be underreporting — because of reluctance of men to acknowledge the problem or to discuss it and because of the lack of physician screening. […] This is the study reported in the Journal of the American Medical Association (JAMA) in 1999 by Laumann, Paik, and Rosen, in which sexual dysfunction in the United States was surveyed with regard specifically to PE. The prevalence was remarkably close to 30% in 4 different decades of life — 18 to 29 years, 30 to 39 years, 40 to 49 years, and 50 to 59 years. Other studies show that there is continued prevalence of PE beyond age 59 years, although it may decline somewhat as men’s penile sensitivity may decline with increasing age due to the onset of neuropathy. But this study shows that the prevalence of PE is about 30% across all ages.

• #5 Premature Ejaculation | Treatment & Management | Point of Care

  https://www.statpearls.com/point-of-care/27656

  Premature ejaculation is the most frequently encountered sexual dysfunction worldwide. Approximately 30% of adult men aged 18 to 59 report having problems with premature ejaculation, but some reports put the prevalence as high as 75%. Additionally, 30% of men with premature ejaculation also report experiencing erectile dysfunction, in which case early ejaculation occurs in the absence of a full erection. […] Although premature ejaculation can occur at any adult age, it is most commonly reported in the 18 to 30-year-old age group and, together with erectile dysfunction, in the 45 to 65-year age group. Ethnically, premature ejaculation may be more prevalent among African Americans (34%) compared to Hispanics (27%) or Whites (29%). Internationally, the estimated incidence in Europe and India is similar to the United States. The prevalence of premature ejaculation in Asia, Australia, Africa, and other parts of the world is not reported.

• #6 Premature Ejaculation: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/435884-overview

  Premature (early) ejaculation is the most common sexual disorder in men younger than 40 years, with 30-70% of males in the United States affected to some degree at one time or another. […] An estimated 30%-70% of American males experience premature ejaculation. The National Health and Social Life Survey (NHSLS) indicates a prevalence of 30%, which is fairly steady through all adult age categories. […] Estimates of premature ejaculation in European countries and India mirror the prevalence in the United States. […] According to the DSM-5, the estimated prevalence of premature (early) ejaculation is highly variable and depends on the definition being employed. […] Premature ejaculation can occur at virtually any age in an adult man’s life. As a reported condition, it is most common in men aged 18-30 years but may also occur in conjunction with secondary impotence in men aged 45-65 years. […] At present, there are no reproducible data indicating major differences between racial groups with respect to the incidence or prevalence of premature ejaculation. However, a few surveys suggest that some degree of racial variation may exist.

• #7 Premature ejaculation – Wikipedia

  https://en.wikipedia.org/wiki/Premature_ejaculation

  Premature ejaculation is a prevalent sexual dysfunction in males; however, because of the variability in time required to ejaculate and in partners’ desired duration of sex, exact prevalence rates of PE are difficult to determine. […] In the „Sex in America” surveys (1999 and 2008), University of Chicago researchers found that between adolescence and age 59, approximately 30% of men reported having experienced PE at least once during the previous 12 months, whereas about 10 percent reported erectile dysfunction (ED). […] Other studies report PE prevalence ranging from 3 percent to 41 percent of men over 18, but the great majority estimate a prevalence of 20 to 30 percent making PE a very common sex problem. […] Prevalence studies have indicated, however, that rates of PE are relatively constant across age groups.

• #8 Clinical Review: Premature ejaculation | GPonline

  https://www.gponline.com/clinical-review-premature-ejaculation/mens-health/mens-health/article/1334583

  Premature ejaculation (PE) is one of the most common conditions reported by men in various health surveys across the globe. […] Although the history of PE dates back more than a century, it is difficult to assess its exact prevalence because of changing definitions and problems with interpreting the data from various studies. […] The National Health and Social Life Survey suggested a prevalence of about 31% in the US, while a British survey estimated it at 14% to 31%. […] The Global Study of Sexual Attitudes and Behaviors survey was conducted in 29 countries in men aged 40 to 80 years and estimated worldwide prevalence at about 30%. […] Most men with PE do not seek medical advice, so there is a significant difference between prevalence rates in the general population and patients presenting to their GP. […] All current studies suggest further research is needed in this field.

• #9 Evolving Diagnosis and Management of Ejaculatory Disorders: A Focus on Premature Ejaculation

  https://www.medscape.org/viewarticle/508092

  This is a study, reported in Urology in 2004, showing the prevalence of PE in 7 different regions of the world. With the exception of the Middle East, which is 12%, the prevalence of PE in all of the other regions was from 20% to 30%; it’s remarkably consistent worldwide. […] A partial summary at this point is that normal ejaculatory latency times can vary widely, although less than 3 minutes is common for men with PE. There are various definitions of PE, but most of the definitions refer to the ejaculatory latency time, control issues, and sexual satisfaction. PE prevalence is consistent at about 30% across all ages. The etiology is multifactorial, but a neurobiologic basis is being increasingly acknowledged. There may be comorbidities and risk factors including, particularly, erectile dysfunction.

• #10 The epidemiology of premature ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5001986/

  In an attempt to remedy the disparity among reported prevalence rates, the International Society for Sexual Medicine (ISSM) developed an evidence-based definition and established set operational criteria. […] Both of these definitions include three main parameters: ejaculatory latency time, distress and ejaculating before desired. […] Some of the first to recognize the need for a specific definition of PE were Waldinger and Schweitzer, who hypothesized that the true prevalence of patients actually seeking treatment for PE was much less than previously reported prevalence rates. […] They proposed a new classification system of PE. […] Further stratifying these complaints into the classifications defined, the complaint of lifelong PE was seen at rates of 2.3% and 3.2%, while the rates of acquired PE were 3.9% and 4.5%, variable PE were 8.5% and 11.4% and subjective PE were 5.1% and 6.4%.

• #11 The epidemiology of premature ejaculation – Robert Saitz – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10575/html

  In an attempt to remedy the disparity among reported prevalence rates, the International Society for Sexual Medicine (ISSM) developed an evidence-based definition and established set operational criteria. […] Both of these definitions include three main parameters: ejaculatory latency time, distress and ejaculating before desired. […] A recent interesting statistical analysis took all three of these operational criteria into account and found that modifying each individual operational criterion could significantly alter the prevalence rates of PE. […] Some of the first to recognize the need for a specific definition of PE were Waldinger and Schweitzer, who hypothesized that the true prevalence of patients actually seeking treatment for PE was much less than previously reported prevalence rates.

• #12 The epidemiology of premature ejaculation – Robert Saitz – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10575/html

  Based on their classification system, two separate observational, cross-sectional surveys from two different continents found that the overall prevalence of the complaint of PE to be 19.8% and 25.80%. […] Further stratifying these complaints into the classifications defined, the complaint of lifelong PE was seen at rates of 2.3% and 3.2%, while the rates of acquired PE were 3.9% and 4.5%, variable PE were 8.5% and 11.4% and subjective PE were 5.1% and 6.4%. […] Interestingly both of these studies found that men with acquired PE were more likely to seek treatment when compared to men with lifelong PE. […] Several recent studies applying up-to-date definitions and operational criteria have examined the prevalence of PE in men with other associated urologic complaints. […] The results from these studies are promising with regards to developing an understanding of the true prevalence of PE according to the newly adapted definitions.

• #13 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/epidemiology-and-prevalence-of-sexual-dysfunction-and-disorders-of-male-reproductive-health

  Further stratifying these complaints into the classifications defined by Waldinger et al., rates of lifelong PE were 2.3 and 3.18%, acquired PE 3.9 and 4.48%, variable PE 8.5 and 11.38% and subjective PE 5.1 and 6.4%, respectively. […] Both studies showed that men with acquired PE were more likely to seek treatment compared to men with lifelong PE.

• #14 The epidemiology of premature ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5001986/

  Interestingly both of these studies found that men with acquired PE were more likely to seek treatment when compared to men with lifelong PE. […] Thus, it is likely that a disparity exists between the incidence of various PE sub-types in the general community and in men actively seeking treatment for PE. […] Several recent studies applying up-to-date definitions and operational criteria have examined the prevalence of PE in men with other associated urologic complaints. […] The results from these studies are promising with regards to developing an understanding of the true prevalence of PE according to the newly adapted definitions. […] The new criteria and classification of PE will allow for continued research into the diverse phenomenology, etiology and pathogenesis of the disease to be conducted. […] While the absolute pathophysiology and true prevalence of PE remains unclear, developing a better understanding of the true prevalence of the disease will allow for the completion of more accurate analysis and treatment of the disease.

• #15 Premature Ejaculation – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK546701/

  Premature ejaculation is the most frequently encountered sexual dysfunction worldwide. Approximately 30% of adult men aged 18 to 59 report having problems with premature ejaculation, but some reports put the prevalence as high as 75%. […] Additionally, 30% of men with premature ejaculation also report experiencing erectile dysfunction, in which case early ejaculation occurs in the absence of a full erection. […] Although premature ejaculation can occur at any adult age, it is most commonly reported in the 18 to 30-year-old age group and, together with erectile dysfunction, in the 45 to 65-year age group. Ethnically, premature ejaculation may be more prevalent among African Americans (34%) compared to Hispanics (27%) or Whites (29%). […] Internationally, the estimated incidence in Europe and India is similar to the United States. The prevalence of premature ejaculation in Asia, Australia, Africa, and other parts of the world is not reported.

• #16 Premature Ejaculation: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/435884-overview

  Premature (early) ejaculation is the most common sexual disorder in men younger than 40 years, with 30-70% of males in the United States affected to some degree at one time or another. […] An estimated 30%-70% of American males experience premature ejaculation. The National Health and Social Life Survey (NHSLS) indicates a prevalence of 30%, which is fairly steady through all adult age categories. […] Estimates of premature ejaculation in European countries and India mirror the prevalence in the United States. […] According to the DSM-5, the estimated prevalence of premature (early) ejaculation is highly variable and depends on the definition being employed. […] Premature ejaculation can occur at virtually any age in an adult man’s life. As a reported condition, it is most common in men aged 18-30 years but may also occur in conjunction with secondary impotence in men aged 45-65 years. […] At present, there are no reproducible data indicating major differences between racial groups with respect to the incidence or prevalence of premature ejaculation. However, a few surveys suggest that some degree of racial variation may exist.

• #17 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Ejaculation is a complex physiological process that comprises emission and expulsion processes and is mediated by interwoven neurological and hormonal pathways. Any interference with those pathways may cause a wide range of ejaculatory disorders. The spectrum of ejaculation disorders includes premature ejaculation (PE), retarded or delayed ejaculation, anejaculation, painful ejaculation, retrograde ejaculation, anorgasmia and haemospermia. […] Historically, the main problem in assessing the prevalence of PE has been the lack of a universally recognised definition at the time that surveys were conducted. […] According to the National Health and Social Life Survey (NHSLS), the prevalence of PE is not affected by age, unlike ED, which increases with age. Premature ejaculation is not affected by marital or income status. However, PE is more common in Black men, Hispanic men, and men from regions where an Islamic background is common and the prevalence may be higher in men with a lower educational level.

• #18 Premature Ejaculation – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK546701/

  Premature ejaculation is the most frequently encountered sexual dysfunction worldwide. Approximately 30% of adult men aged 18 to 59 report having problems with premature ejaculation, but some reports put the prevalence as high as 75%. […] Additionally, 30% of men with premature ejaculation also report experiencing erectile dysfunction, in which case early ejaculation occurs in the absence of a full erection. […] Although premature ejaculation can occur at any adult age, it is most commonly reported in the 18 to 30-year-old age group and, together with erectile dysfunction, in the 45 to 65-year age group. Ethnically, premature ejaculation may be more prevalent among African Americans (34%) compared to Hispanics (27%) or Whites (29%). […] Internationally, the estimated incidence in Europe and India is similar to the United States. The prevalence of premature ejaculation in Asia, Australia, Africa, and other parts of the world is not reported.

• #19 Prevalence of Premature Ejaculation: A Narrative Review of National and Cultural Differences

  https://www.mdpi.com/2411-5118/5/4/43

  The prevalence of premature ejaculation (PE) across different cultures and nationalities has long been a topic of debate, with early studies suggesting that men in such regions as the Middle East and Asia experience higher rates. However, the validity of these claims has been questioned due to methodological inconsistencies and the lack of comparative studies that apply uniform diagnostic criteria across different populations. […] The review found that differences in PE prevalence across cultures are more likely due to methodological variations than true cultural or national differences. While some trends, such as slightly higher rates in Latin American and Asian countries, were noted, no consistent patterns emerged. Studies using standardized methods, like the PEDT, generally showed prevalence rates between 5% and 15%, with no clear outliers across regions. Thus, current evidence does not support significant cultural or national differences in PE prevalence.

• #20 Prevalence of Premature Ejaculation: A Narrative Review of National and Cultural Differences

  https://www.mdpi.com/2411-5118/5/4/43

  The idea that men from different regions of the world might demonstrate different prevalence rates has not been given an adequate examination and vetting, due to the methodological issues that have arisen in the establishment of PE rates. […] Overall, these studies suggest a wide range of prevalence rates, but generally variance in prevalence appears to result more from differences in methodological assessment of PE than to differences arising from national/regional/cultural origins. […] Data from individual countries situated in various world regions generally have not supported preliminary impressions of unusually high or low prevalence rates in some regions. Asian countries do not, on average, exhibit particularly high or low prevalence rates. Middle Eastern countries appear to fall within typical ranges.

• #21 Premature Ejaculation – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK546701/

  Premature ejaculation is the most frequently encountered sexual dysfunction worldwide. Approximately 30% of adult men aged 18 to 59 report having problems with premature ejaculation, but some reports put the prevalence as high as 75%. […] Additionally, 30% of men with premature ejaculation also report experiencing erectile dysfunction, in which case early ejaculation occurs in the absence of a full erection. […] Although premature ejaculation can occur at any adult age, it is most commonly reported in the 18 to 30-year-old age group and, together with erectile dysfunction, in the 45 to 65-year age group. Ethnically, premature ejaculation may be more prevalent among African Americans (34%) compared to Hispanics (27%) or Whites (29%). […] Internationally, the estimated incidence in Europe and India is similar to the United States. The prevalence of premature ejaculation in Asia, Australia, Africa, and other parts of the world is not reported.

• #22 Premature Ejaculation | Treatment & Management | Point of Care

  https://www.statpearls.com/point-of-care/27656

  Premature ejaculation is the most frequently encountered sexual dysfunction worldwide. Approximately 30% of adult men aged 18 to 59 report having problems with premature ejaculation, but some reports put the prevalence as high as 75%. Additionally, 30% of men with premature ejaculation also report experiencing erectile dysfunction, in which case early ejaculation occurs in the absence of a full erection. […] Although premature ejaculation can occur at any adult age, it is most commonly reported in the 18 to 30-year-old age group and, together with erectile dysfunction, in the 45 to 65-year age group. Ethnically, premature ejaculation may be more prevalent among African Americans (34%) compared to Hispanics (27%) or Whites (29%). Internationally, the estimated incidence in Europe and India is similar to the United States. The prevalence of premature ejaculation in Asia, Australia, Africa, and other parts of the world is not reported.

• #23 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  A significant proportion of men with ED also experience PE. High levels of performance anxiety related to ED may worsen PE, with a risk of misdiagnosing PE instead of the underlying ED. […] Men with PE are more likely to report low satisfaction with their sexual relationship, low satisfaction with sexual intercourse, difficulty relaxing during intercourse, and less-frequent intercourse. Premature ejaculation can have a detrimental effect on self-confidence and the relationship with the partner, and may sometimes cause mental distress, anxiety, embarrassment and depression. […] Despite the possible serious psychological and QoL consequences of PE, few men seek treatment. […] There is still little consensus about the definition and classification of PE. It is now universally accepted that premature ejaculation is a broad term that includes several concepts belonging to the common category of PE.

• #24 Lower Urinary Tract Symptoms Correlate with Erectile Dysfunction and Premature Ejaculation but Not with Men’s Sexual Activity: Results from a Large Population-Representative Study

  https://www.mdpi.com/2227-9032/12/14/1408

  Lower urinary tract symptoms (LUTS) contribute to erectile dysfunction (ED) and premature ejaculation (PE). […] Although the association of LUTS with premature ejaculation (PE) has received less scrutiny compared with LUTS and ED, Sihotang et al., in their recent systematic review with a meta-analysis, hypothesized that there is a correlation between LUTS and PE. […] ED and PE are the most prevalent and the most stressful of men’s sexual dysfunctions; thus, investigators and clinicians should accurately assess LUTS/ED/PE correlations because these conditions independently impair men’s quality of life and psychological well-being. […] The study showed that ED was strongly related to LUTS and that this relation was independent of reported comorbidities. […] The regression models showed that LUTS were significantly associated with PE, but the authors underlined the fact that their PE model was less robust than the other logistic regression analyses; therefore, the authors recommended caution in interpreting their results.

• #25 Lower Urinary Tract Symptoms Correlate with Erectile Dysfunction and Premature Ejaculation but Not with Men’s Sexual Activity: Results from a Large Population-Representative Study

  https://www.mdpi.com/2227-9032/12/14/1408

  In our study with the PEDT, a well-known instrument with high specificity and sensitivity in detecting PE, we showed a significant correlation between LUTS and PE, and notably, the effect of LUTS on PE was not influenced by age, comorbidities, or lifestyle factors. […] Although we observed the negative effects of coexisting LUTS and ED or LUTS and PE on both quality of sexual life and overall quality of life, our regression models did not validate the effect of LUTS on men’s sexual activity concerning the frequency of sexual intercourse and the number of sexual partners. […] In this study, with well-balanced demographic characteristics, we confirmed the contributory effects of LUTS on ED and PE.

• #26

  https://journals.lww.com/md-journal/fulltext/2016/08300/relationship_between_premature_ejaculation_and.39.aspx

  Premature ejaculation (PE) is the most prevalent male sexual dysfunction. Epidemiologic findings are inconsistent concerning the risk for depression associated with PE. […] Eight trials involving 18,035 patients were included in the meta-analysis. Depression were statistically significantly associated with the risk of PE (OR = 1.63, 95% CI:1.421.87). […] These findings provide evidence that depression is associated with a significantly increased risk of PE. […] The prevalence of PE did not vary significantly in young and middle-aged men, indicating that no particular age group has consistently been shown to be at greater risk for PE. […] Individual psychological factors such as depression, stress, anxiety, and negative cognitive processing are strongly associated with the onset and maintenance of male sexual difficulties.

• #27

  https://journals.lww.com/md-journal/fulltext/2016/08300/relationship_between_premature_ejaculation_and.39.aspx

  Previous studies have shown that negative psychological disorders might play an important role in precipitating or maintaining PE. […] The relationship between depression and PE might be bidirectional. […] In conclusion, this meta-analysis of observational studies suggests that depression is significantly associated with an increased risk of PE.

• #28 The prevalence of premature ejaculation and its relationship with polygamous men: a cross-sectional observational study at a tertiary hospital in Somalia | BMC Urology | Full Text

  https://bmcurol.biomedcentral.com/articles/10.1186/s12894-021-00942-0

  Premature ejaculation (PE) is the most common and prevalent sexual disorder among men. To the best of our knowledge, this is the first study aimed at evaluating the relationship of PE among polygamous men. […] In our study, the prevalence of PE was 37.1%; half of the monogamous men (50%) complained of PE, while 22% of men with two wives, 20% of men with three wives, and 12% of men with four wives complained of PE. […] We report that polygamous men have a lower incidence of premature ejaculation and higher sexual satisfaction than monogamous men. […] The study results indicate that a sexual intercourse frequency of two or more times per week significantly lowers the risk of PE. […] Premature ejaculation is the most common and prevalent sexual disorder among men, affecting 30% to 50% of the male population.

• #29 The prevalence of premature ejaculation and its relationship with polygamous men: a cross-sectional observational study at a tertiary hospital in Somalia | BMC Urology | Full Text

  https://bmcurol.biomedcentral.com/articles/10.1186/s12894-021-00942-0

  Several studies have focused on the impact of premature ejaculation and depression and female sexual satisfaction for men with premature ejaculation. […] Our study indicated that there is a statistically significant difference between the number of sexual partners and PE. Polygamous men have a lower incidence of premature ejaculation and higher sexual satisfaction than monogamous men. […] The study results indicate that a sexual intercourse frequency of two or more times per week significantly lowers the risk of PE. […] In our study, the prevalence of PE was 37.1%, which was higher than that reported in previous studies. […] A new taxonomic entity called loss of control of erection and ejaculation (LCEE) was introduced by Colonnello et al. that sights the two sexual symptoms as deeply interrelated, and helps the assessment of concomitant presence of PE and ED, and to improve both PE diagnosis and management. […] The coexistence of PE and ED should be carefully evaluated and should not be considered to be separate entities that would increase treatment failure rates.

• #30 The epidemiology of premature ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5001986/

  In an attempt to remedy the disparity among reported prevalence rates, the International Society for Sexual Medicine (ISSM) developed an evidence-based definition and established set operational criteria. […] Both of these definitions include three main parameters: ejaculatory latency time, distress and ejaculating before desired. […] Some of the first to recognize the need for a specific definition of PE were Waldinger and Schweitzer, who hypothesized that the true prevalence of patients actually seeking treatment for PE was much less than previously reported prevalence rates. […] They proposed a new classification system of PE. […] Further stratifying these complaints into the classifications defined, the complaint of lifelong PE was seen at rates of 2.3% and 3.2%, while the rates of acquired PE were 3.9% and 4.5%, variable PE were 8.5% and 11.4% and subjective PE were 5.1% and 6.4%.

• #31 The pathophysiology of acquired premature ejaculation – McMahon – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/11133/html

  The second Ad Hoc International Society for Sexual Medicine (ISSM) Committee for the Definition of Premature Ejaculation defined acquired premature ejaculation (PE) as a male sexual dysfunction characterized by a the development of a clinically significant and bothersome reduction in ejaculation latency time in men with previous normal ejaculatory experiences, often to about 3 minutes or less, the inability to delay ejaculation on all or nearly all vaginal penetrations, and the presence of negative personal consequences, such as distress, bother, frustration and/or the avoidance of sexual intimacy. […] Acquired PE is commonly due to sexual performance anxiety, psychological or relationship problems, erectile dysfunction (ED), and occasionally prostatitis and hyperthyroidism, consistent with the predominant organic etiology of acquired PE, men with this complaint are usually older, have a higher mean BMI and a greater incidence of comorbid disease including hypertension, sexual desire disorder, diabetes mellitus, chronic prostatitis, and ED compared to lifelong, variable and subjective PE.

• #32 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  The most recent definition comes from the International Classification of Diseases 11th Revision, where PE was renamed as Early Ejaculation: Male early ejaculation is characterized by ejaculation that occurs prior to or within a very short duration of the initiation of vaginal penetration or other relevant sexual stimulation, with no or little perceived control over ejaculation. […] The classification of PE into four subtypes has contributed to a better delineation of lifelong, acquired, variable and subjective PE. […] Diagnosis of PE is based on the patients medical and sexual history. History should classify PE as lifelong or acquired and determine whether PE is situational (under specific circumstances or with a specific partner) or consistent. […] Several questionnaires can be used for the diagnosis of PE (PEDT, AIPE) and for assessing the therapeutic outcomes of PE interventions.

• #33 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  The most recent definition comes from the International Classification of Diseases 11th Revision, where PE was renamed as Early Ejaculation: Male early ejaculation is characterized by ejaculation that occurs prior to or within a very short duration of the initiation of vaginal penetration or other relevant sexual stimulation, with no or little perceived control over ejaculation. […] The classification of PE into four subtypes has contributed to a better delineation of lifelong, acquired, variable and subjective PE. […] Diagnosis of PE is based on the patients medical and sexual history. History should classify PE as lifelong or acquired and determine whether PE is situational (under specific circumstances or with a specific partner) or consistent. […] Several questionnaires can be used for the diagnosis of PE (PEDT, AIPE) and for assessing the therapeutic outcomes of PE interventions.

• #34 The pathophysiology of acquired premature ejaculation – McMahon – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/11133/html

  Research into the treatment and epidemiology of PE is heavily dependent on how PE is defined. […] In the last decade, substantial progress has been made in the development of evidence-based methodology for PE epidemiologic and drug treatment research using the objective IELT and subjective validated patient-reported outcome (PRO) measures. […] The committee anticipated that future studies would generate sufficient data to develop an evidence-based definition for acquired PE. […] Reliable information on the prevalence of lifelong and acquired PE in the general male population is lacking. […] PE has been estimated to occur in 4-39% of men in the general community, and is often reported as the most common self reported male sexual disorder. […] The real prevalence of PE is difficult to assess in clinical practice.

• #35 Premature ejaculation: A clinical review for the general physician

  https://www.racgp.org.au/afp/2015/october/premature-ejaculation-a-clinical-review-for-the-ge

  Premature ejaculation is one of the most common sexual dysfunctions in men. Recent epidemiological studies suggest its prevalence in Australia may range from 21-31% […] Premature ejaculation is one of the most common sexual dysfunctions, affecting up to 21-31% of the Australian adult male population, irrespective of their age, marital status or ethnicity. This sexual condition is likely to be under-reported and under-treated because of the patients perceived shame and low self-esteem. […] It is estimated that premature ejaculation affects up to 31% of Australian males.

• #36 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  A significant proportion of men with ED also experience PE. High levels of performance anxiety related to ED may worsen PE, with a risk of misdiagnosing PE instead of the underlying ED. […] Men with PE are more likely to report low satisfaction with their sexual relationship, low satisfaction with sexual intercourse, difficulty relaxing during intercourse, and less-frequent intercourse. Premature ejaculation can have a detrimental effect on self-confidence and the relationship with the partner, and may sometimes cause mental distress, anxiety, embarrassment and depression. […] Despite the possible serious psychological and QoL consequences of PE, few men seek treatment. […] There is still little consensus about the definition and classification of PE. It is now universally accepted that premature ejaculation is a broad term that includes several concepts belonging to the common category of PE.

• #37 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Pharmacotherapy must be considered the first-line treatment for patients with lifelong PE, whereas treating the underlying cause (e.g., ED, prostatitis, LUTS, anxiety and hyperthyroidism) must be the initial goal for patients with acquired PE. […] Dapoxetine (30 and 60 mg) is the first on-demand oral pharmacological agent approved for lifelong and acquired PE in many countries, except for the USA. […] The long-term outcomes of pharmacological treatments are unknown. […] Pharmacotherapy includes either dapoxetine on-demand (an oral short-acting SSRI) and eutectic lidocaine/prilocaine spray (a topical desensitising agent), which are the only approved treatments for PE, or other off-label antidepressants (daily/on-demand SSRIs and clomipramine). […] Both on-demand dapoxetine treatment and daily SSRI treatment improve IELT values significantly. […] Use either dapoxetine or the lidocaine/prilocaine spray as first-line treatments for lifelong premature ejaculation (PE).

• #38 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Pharmacotherapy must be considered the first-line treatment for patients with lifelong PE, whereas treating the underlying cause (e.g., ED, prostatitis, LUTS, anxiety and hyperthyroidism) must be the initial goal for patients with acquired PE. […] Dapoxetine (30 and 60 mg) is the first on-demand oral pharmacological agent approved for lifelong and acquired PE in many countries, except for the USA. […] The long-term outcomes of pharmacological treatments are unknown. […] Pharmacotherapy includes either dapoxetine on-demand (an oral short-acting SSRI) and eutectic lidocaine/prilocaine spray (a topical desensitising agent), which are the only approved treatments for PE, or other off-label antidepressants (daily/on-demand SSRIs and clomipramine). […] Both on-demand dapoxetine treatment and daily SSRI treatment improve IELT values significantly. […] Use either dapoxetine or the lidocaine/prilocaine spray as first-line treatments for lifelong premature ejaculation (PE).

• #39 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  A significant proportion of men with ED also experience PE. High levels of performance anxiety related to ED may worsen PE, with a risk of misdiagnosing PE instead of the underlying ED. […] Men with PE are more likely to report low satisfaction with their sexual relationship, low satisfaction with sexual intercourse, difficulty relaxing during intercourse, and less-frequent intercourse. Premature ejaculation can have a detrimental effect on self-confidence and the relationship with the partner, and may sometimes cause mental distress, anxiety, embarrassment and depression. […] Despite the possible serious psychological and QoL consequences of PE, few men seek treatment. […] There is still little consensus about the definition and classification of PE. It is now universally accepted that premature ejaculation is a broad term that includes several concepts belonging to the common category of PE.

• #40 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  A significant proportion of men with ED also experience PE. High levels of performance anxiety related to ED may worsen PE, with a risk of misdiagnosing PE instead of the underlying ED. […] Men with PE are more likely to report low satisfaction with their sexual relationship, low satisfaction with sexual intercourse, difficulty relaxing during intercourse, and less-frequent intercourse. Premature ejaculation can have a detrimental effect on self-confidence and the relationship with the partner, and may sometimes cause mental distress, anxiety, embarrassment and depression. […] Despite the possible serious psychological and QoL consequences of PE, few men seek treatment. […] There is still little consensus about the definition and classification of PE. It is now universally accepted that premature ejaculation is a broad term that includes several concepts belonging to the common category of PE.

• #41 Premature Ejaculation: Causes and Treatment | Doctor

  https://patient.info/doctor/premature-ejaculation-pro

  The prevalence of premature ejaculation varies according to definition and is difficult to assess in view of many men not wanting to seek help or even discuss the problem. […] The estimated prevalence is likely to be around 1-3% of men, although some studies have reported it to be up to 30%. […] Studies report as well as the detrimental effect on sexual function and relationships, premature ejaculation may lead to reduced quality of life, mental distress, anxiety and depression.

• #42 Population-level prevalence, effect on quality of life, and treatment behavior for erectile dysfunction and premature ejaculation in Poland | Scientific Reports

  https://www.nature.com/articles/s41598-023-39968-9

  The prevalence of erectile dysfunction (ED) and premature ejaculation (PE) has been investigated in many population-based studies in different regions of the world. However, reliable data are lacking for Eastern Europe. […] The prevalence of PE was 19.3% based on PEDT score of 11 points or more (definition II). […] The prevalence of PE did not differ across all geographical regions (voivodships) of Poland. […] The low rate of treatment seeking despite the negative effects of ED and PE on multiple aspects of life is a significant public health concern. […] This investigation was the first nationwide, population-representative epidemiological study of ED and PE performed in Poland. ED and PE were prevalent conditions and had negative effects on quality of life. However, less than one fourth of respondents with ED or PE were seeking treatment.

• #43 The epidemiology of premature ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5001986/

  Vast advances have occurred over the past decade with regards to understanding the epidemiology, pathophysiology and management of premature ejaculation (PE); however, we still have much to learn about this common sexual problem. […] As a standardized evidence-based definition of PE has only recently been established, the reported prevalence rates of PE prior to this definition have been difficult to interpret. […] In addition to the lack of a standardized definition and operational criteria, the method of recruitment for study participation and method of data collection have obviously contributed to the broad range of reported prevalence rates. […] While the absolute pathophysiology and true prevalence of PE remains unclear, developing a better understanding of the true prevalence of the disease will allow for the completion of more accurate analysis and treatment of the disease.

• #44 The epidemiology of premature ejaculation – Robert Saitz – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10575/html

  Vast advances have occurred over the past decade with regards to understanding the epidemiology, pathophysiology and management of premature ejaculation (PE); however, we still have much to learn about this common sexual problem. […] As a standardized evidence-based definition of PE has only recently been established, the reported prevalence rates of PE prior to this definition have been difficult to interpret. […] A large range of conflicting prevalence rates have been reported. […] In addition to the lack of a standardized definition and operational criteria, the method of recruitment for study participation and method of data collection have obviously contributed to the broad range of reported prevalence rates. […] While the absolute pathophysiology and true prevalence of PE remains unclear, developing a better understanding of the true prevalence of the disease will allow for the completion of more accurate analysis and treatment of the disease.

• #45 The epidemiology of premature ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5001986/

  Interestingly both of these studies found that men with acquired PE were more likely to seek treatment when compared to men with lifelong PE. […] Thus, it is likely that a disparity exists between the incidence of various PE sub-types in the general community and in men actively seeking treatment for PE. […] Several recent studies applying up-to-date definitions and operational criteria have examined the prevalence of PE in men with other associated urologic complaints. […] The results from these studies are promising with regards to developing an understanding of the true prevalence of PE according to the newly adapted definitions. […] The new criteria and classification of PE will allow for continued research into the diverse phenomenology, etiology and pathogenesis of the disease to be conducted. […] While the absolute pathophysiology and true prevalence of PE remains unclear, developing a better understanding of the true prevalence of the disease will allow for the completion of more accurate analysis and treatment of the disease.

• #46 Premature Ejaculation Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

  https://www.researchandmarkets.com/reports/5970382/premature-ejaculation-market-epidemiology?srsltid=AfmBOopbY35Y3L4Q3K-_Xt2bAuFHh8Wen1GIAVYzhQ1nwQq5fqMSMPUT

  The 7 major premature ejaculation markets reached a value of US$ 2.4 Billion in 2023. Looking forward, the publisher expects the 7MM to reach US$ 5.3 Billion by 2034, exhibiting a growth rate (CAGR) of 9.20% during 2023-2034. […] Premature ejaculation refers to a common sexual health concern that affects many men, characterized by the inability to control ejaculation during sexual activity. It is defined as the occurrence of ejaculation before or shortly after penetration, often leading to dissatisfaction for both partners. This condition may cause emotional distress, relationship strain, and reduced self-esteem. […] The increasing prevalence of various psychological factors associated with the ailment, such as early sexual experiences, sexual abuse, poor body image, depression, anxiety, etc., is primarily driving the premature ejaculation market.

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