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• #1 Truncus arteriosus | Beacon Health System

  https://www.beaconhealthsystem.org/library/diseases-and-conditions/truncus-arteriosus?content_id=CON-20316974

  Symptoms of truncus arteriosus most often occur in the first few days of life. They include: […] Blue or gray skin due to low oxygen levels. […] Extreme sleepiness. […] Poor feeding. […] Poor growth. […] Pounding heartbeat. […] Fast breathing. […] Shortness of breath. […] Truncus arteriosus causes severe problems with how blood flows through the lungs, heart and rest of the body. […] Complications of truncus arteriosus in babies include: […] Breathing problems. […] High blood pressure in the lungs, also called pulmonary hypertension. […] Enlargement of the heart. […] Heart failure. […] Infants who had their hearts successfully fixed with surgery may still have complications later in life. Possible complications are: […] Pulmonary hypertension that gets worse. […] Backward flow of blood through a heart valve, called regurgitation.

• #2 Truncus Arteriosus | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/truncus-arteriosus

  Signs and symptoms of truncus arteriosus usually appear within the first days of life and may include: […] Blue or purple tint to lips, skin and nails (cyanosis) […] Rapid breathing or shortness of breath […] More sleepiness than normal […] Unresponsiveness […] Truncus arteriosus is a life-threatening congenital heart defect; most babies won’t live for more than a few months without treatment. […] Sometimes children with truncus arteriosus experience heart problems later in life, including irregular heartbeat (arrhythmia), a restricted conduit or pulmonary artery, or a leaky aortic valve.

• #3 Truncus Arteriosus: Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/14785-truncus-arteriosus

  Signs and symptoms typically appear within the first few days of life and include: […] Blue or gray skin color (cyanosis), especially around your babys mouth and fingertips […] Excessive sleepiness […] Fast heart rate […] Slow weight gain […] Trouble breathing […] Trouble feeding, including falling asleep or sweating while feeding […] Weak pulse. […] Your baby needs surgery soon after birth to correct the problem and have normal blood flow. […] The survival rate for truncus arteriosus surgery is 80% to 97%, according to the latest research. […] About 75% of babies who have surgical repair are alive 20 years later. Most deaths occur within one year of repair. About 92.5% of babies who survive to one year after surgery are alive at 20 years.

• #4 About Truncus Arteriosus | Congenital Heart Defects (CHDs) | CDC

  https://www.cdc.gov/heart-defects/about/truncus-arteriosus.html

  Infants with truncus arteriosus usually are in distress in the first few days of life. This is because of the high amount of blood going to the lungs which makes the heart work harder. […] Infants with truncus arteriosus can have a bluish looking skin color, called cyanosis, because their blood doesn’t carry enough oxygen. […] Infants with truncus arteriosus or other conditions causing cyanosis can have symptoms such as: Problems breathing, Fast heart rate, Weak pulse, Ashen or bluish skin color, Poor feeding, Extreme sleepiness. […] Most babies with truncus arteriosus survive the surgical repair, but may need more surgery or other procedures as they get older. […] A person born with truncus arteriosus will need regular follow-up visits with a cardiologist (a heart doctor). These visits will help monitor their progress and avoid complications or other health problems.

• #5 Truncus Arteriosus > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/truncus-arteriosus

  Symptoms include bluish skin, shortness of breath, rapid breathing, pounding heartbeat, weak pulse. […] Babies born with truncus arteriosus usually experience heart failure within the first few weeks of life. […] The condition causes heart failure, and, without treatment, babies may die within the first year of life. […] Newborns with truncus arteriosus have bluish skin and may begin to experience heart failure symptoms, including: Bluish skin, Shortness of breath, Rapid breathing, A pounding heartbeat, Weak pulse, Poor feeding habits, Sweating, Extreme sleepiness or lethargy, Heart murmur, Enlarged liver. […] Truncus arteriosus is a life-threatening condition. More than 70% of babies born with this birth defect who do not undergo surgery will die in the first year of life. […] The surgical correction of truncus arteriosus helps many patients lead normal lives. After surgery, more than 80% of patients live to age 20 or older. […] By age 10, 75% of patients require another procedure to keep the heart functioning well.

• #6 Truncus Arteriosus (TA)

  https://library.valleymed.org/library/Wellness/Safety/90,P01826

  Symptoms of truncus arteriosus include: […] Blue color to skin, lips, and nails (cyanosis) […] Problems breathing […] Poor feeding or eating […] Tiredness (fatigue) […] Enlarged liver […] Extreme sleepiness. […] The symptoms of truncus arteriosus can be like other health conditions. Have your child see their healthcare provider for a diagnosis. […] Soon after surgery, babies have more energy and start to eat better and gain weight faster. But your baby may need high-calorie formula for several weeks or months after surgery. Your baby may also need tube feedings until they are able to feed better. […] Your baby may become tired easily, and sleep more right after surgery. But in a few weeks, they should be fully recovered. […] Most children who have had truncus arteriosus surgical repair will live healthy lives. Their activity levels, appetite, and growth will often return to normal.

• #7 Truncus Arteriosus | Symptoms, Diagnosis & Treatment

  https://www.cincinnatichildrens.org/health/t/truncus-arteriosus

  A baby with truncus arteriosus begins to have problems in the first week of life. Their oxygen levels are often lower than normal. This results in a cyanosis (bluish color of the skin). […] Because of the large amount of blood flow to the lungs with this defect, congestive heart failure (CHF) develops in the first week or two of life. On a chest X-ray, the heart looks big. The lung fields look hazy. This indicates pulmonary over-circulation (extra blood to the lungs). […] Signs of congestive heart failure are fast breathing, wheezing, trouble breathing, grunting or very noisy breathing, increased work of breathing (pulling under the ribs, nasal flaring) and restlessness. […] The signs and symptoms often get worse when the infant eats.

• #8 Truncus Arteriosus: Symptoms & Causes | NewYork-Presbyterian

  https://www.nyp.org/pediatrics/heart/truncus-arteriosus

  Truncus arteriosus is a serious condition for an infant, and immediate attention must be given to the signs and symptoms which usually appear within the first few days of life. Symptoms may include: Rapid, heavy, and congested breathing […] Cyanosis, which causes skin, lips, and nail beds to turn blue. If your baby is having difficulty breathing or their skin color begins to turn blue, seek immediate medical attention. Truncus arteriosus combined with an abnormal heart structure results in serious blood circulation problems. The lack of separation of the blood ventricles causes all the blood to flow through one single artery. The oxygen-rich blood mixes with the oxygen-poor blood […] Babies with truncus arteriosus experience abnormal blood circulation. This can result in: Respiratory issues

• #9 Persistent Truncus Arteriosus – Pediatrics – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/pediatrics/congenital-cardiovascular-anomalies/persistent-truncus-arteriosus

  Persistent truncus arteriosus occurs when, during fetal development, the primitive truncus does not divide into the pulmonary artery and aorta, resulting in a single, large, arterial trunk that overlies a large, malalignment type ventricular septal defect. Consequently, a mixture of oxygenated and deoxygenated blood enters systemic, pulmonary, and coronary circulations. Symptoms include cyanosis and heart failure, with poor feeding, diaphoresis, and tachypnea. […] Infants usually present with mild cyanosis and symptoms and signs of heart failure (eg, tachypnea, poor feeding, diaphoresis) in the first few weeks of life. […] Patients present with mild cyanosis, significant pulmonary overcirculation, and heart failure; a grade 2 to 4/6 systolic murmur is audible along the left sternal border and a mid-diastolic mitral flow murmur may be audible at the apex, and bounding peripheral pulses. […] Physiologic consequences of truncus arteriosus include mild cyanosis, significant pulmonary overcirculation, and heart failure.

• #10 Truncus arteriosus | Causes, symptoms, diagnosis | Children’s Wisconsin

  https://childrenswi.org/medical-care/herma-heart/conditions/truncus-arteriosus

  In babies born with truncus arteriosus the blood passing through their systems is poor in oxygen, causing difficulty breathing, rapid heart rate, varying degrees of cyanosis (blue color of the skin, lips and nailbeds), and other symptoms. […] The following are the most common symptoms of truncus arteriosus. However, each child may experience symptoms differently. Symptoms may include: Cyanosis, Fatigue, Sweating, Pale skin, Cool skin, Rapid breathing, Heavy breathing, Rapid heart rate, Congested breathing, Disinterest in feeding, or tiring while feeding, Poor weight gain. […] The blood that passes through the common truncal vessel has a lower oxygen content than normal. Oxygen-poor (blue) blood from the right ventricle and oxygen-rich (red) blood from the left ventricle mix together before entering the common vessel. Some of this mixed blood will go into the aorta and on to the body, producing cyanosis (blue color of the skin, lips, and nailbeds). […] If not repaired, the blood vessels in the lungs become damaged by the extra blood flow. As the pressure in the blood vessels in the lungs becomes higher, less blood goes to the lungs and more goes to the body. Cyanosis becomes worse as blood with lower amounts of oxygen travels to the body.

• #11 Truncus Arteriosus (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/truncus-arteriosus.html

  Truncus arteriosus (TRUNG-kus ar-teer-ee-OH-sus) is a heart defect that happens when a baby is born with one large artery carrying blood to the lungs and body instead of two separate arteries. […] A baby with truncus arteriosus may: have a blue or purple tint to the skin, have fast or labored breathing, have problems with feeding, not gain weight as expected, be very sleepy, have increased sweating, especially while feeding. […] A child born with truncus arteriosus might not look sick right away. But if the condition isn’t treated early, truncus arteriosus can quickly lead to heart failure and other life-threatening complications.

• #12 Truncus Arteriosus – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK534774/

  Without the recommended single-stage repair, patients often die before 2 months of age. The 1-year survival rate for patients who do not undergo surgery is less than 20%. […] After the primary repair, patients have a 20-year survival rate of over 80%, but the reoperation rate remains high. Therefore, long-term follow-up is recommended.

• #13 Truncus arteriosus – Augusta HealthSearchClose SearchSearch IconSearch IconClose Search IconMobile Menu IconMobile Menu Close IconInstagramFacebookTwitterYoutube

  https://www.augustahealth.com/disease/truncus-arteriosus/

  Signs and symptoms of truncus arteriosus often develop in the first few days of life. They include: Blue coloring of the skin, Poor feeding, Pounding heart, Excessive sleepiness, Poor growth, Shortness of breath, Rapid breathing. […] Some signs of truncus arteriosus can indicate a problem that needs urgent care. If your baby has any of the following signs and symptoms and you can’t see your baby’s doctor immediately, seek emergency medical care: Rapid, shallow or labored breathing, Worsening of blue coloring of the skin, Loss of consciousness. […] The abnormal heart structures of truncus arteriosus result in severe problems with blood circulation. Because the ventricles aren’t separated and all blood exits from a single vessel, the oxygen-rich blood and the oxygen-poor blood mix — resulting in blood that doesn’t carry enough oxygen. The mixed blood flows from the single large vessel to the lungs, the arteries of the heart and the rest of the body.

• #14 Truncus arteriosus – Augusta HealthSearchClose SearchSearch IconSearch IconClose Search IconMobile Menu IconMobile Menu Close IconInstagramFacebookTwitterYoutube

  https://www.augustahealth.com/disease/truncus-arteriosus/

  If your baby has truncus arteriosus, the abnormal circulation of blood usually results in: Respiratory problems. Too much blood flows into the lungs, and the excess fluid makes it difficult for your baby to breathe. High blood pressure in the lungs (pulmonary hypertension). Increased blood flow to the lungs causes the lungs’ blood vessels to narrow, increasing blood pressure in the lungs and making it increasingly difficult for your baby’s heart to pump blood into the lungs. Enlargement of the heart (cardiomegaly). Pulmonary hypertension and the increased blood flow through the heart force your baby’s heart to work harder than normal, causing it to enlarge. The enlarged heart gradually weakens. Heart failure. The increased workload and poor oxygen supply also result in weakening of your baby’s heart. These factors can contribute to heart failure, the inability of the heart to supply the body with enough blood.

• #15 Truncus arteriosus: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/001111.htm

  Symptoms include: […] Bluish color to the skin (cyanosis) due to low oxygen level in the blood […] Delayed growth or growth failure […] Fatigue […] Lethargy […] Poor feeding […] Rapid breathing (tachypnea) […] Shortness of breath (dyspnea) […] Widening of the finger tips (clubbing) […] If this condition is not treated, two problems occur: […] Too much blood circulation in the lungs may cause extra fluid to build up in and around them. This makes it hard to breathe. […] If left untreated and more than normal blood flows to the lungs for a long time, the blood vessels to the lungs become permanently damaged. Over time, it becomes very hard for the heart to force blood through them. This is called pulmonary hypertension, which can be life threatening. […] Untreated cases of truncus arteriosus result in death, often during the first year of life.

• #16 Truncus arteriosus – Augusta HealthSearchClose SearchSearch IconSearch IconClose Search IconMobile Menu IconMobile Menu Close IconInstagramFacebookTwitterYoutube

  https://www.augustahealth.com/disease/truncus-arteriosus/

  Even with successful surgical repair of the heart during infancy, other complications associated with truncus arteriosus can occur later in life: Progressive pulmonary hypertension, Leaky heart valves (regurgitation), Heart rhythm disturbances (arrhythmias), Problems related to prior operation. Common signs and symptoms of these complications include shortness of breath when exercising, dizziness, fatigue, abdominal swelling, swelling in the legs and feet, and a sensation of rapid, fluttering heartbeats (palpitations). […] In rare cases, a person with truncus arteriosus can survive infancy without surgical repair of the heart and live into adulthood. However, people with this condition will almost certainly develop heart failure and pulmonary hypertension (Eisenmenger syndrome). This syndrome is caused by permanent lung damage from pulmonary hypertension that results in much of the blood flow bypassing the lungs entirely.

• #17 Truncus arteriosus | Beacon Health System

  https://www.beaconhealthsystem.org/library/diseases-and-conditions/truncus-arteriosus?content_id=CON-20316974

  Irregular heartbeats, called arrhythmias. […] Common symptoms of these complications include: […] Dizziness. […] Feeling very fast, fluttering heartbeats. […] Feeling very tired. […] Shortness of breath when exercising. […] Swelling of the belly, legs or feet. […] In rare cases, some people born with truncus arteriosus can survive without heart surgery. They may live into adulthood. But those with the condition will almost certainly have heart failure and develop a complication called Eisenmenger syndrome. This syndrome is caused by permanent lung vessel damage. It results in a significant lack of blood flow to the lungs.

• #18 Truncus Arteriosus – ACHA

  https://www.achaheart.org/your-heart/educational-qas/types-of-heart-defects/truncus-arteriosus/

  Most issues that adults develop are the result of complications from their primary surgery. These include: Truncal stenosis or regurgitation, Stenosis or regurgitation of the right ventricle to pulmonary artery conduit(s), Ventricular dysfunction, Arrhythmias or irregular heartbeats, Pulmonary hypertension or high blood pressure in the lungs, if untreated or if there was late repair.

• #19 Truncus Arteriosus | American Heart Association

  https://www.heart.org/en/health-topics/congenital-heart-defects/about-congenital-heart-defects/truncus-arteriosus

  Truncus arteriosus causes symptoms of heart failure early in life. If it’s not repaired, severe pulmonary hypertension occurs. […] The blood leaving the heart can go the heart or lungs. Early in life this results in quite a bit of extra blood going to the lungs, which makes the heart work very hard. Over time the extra blood flow damages the blood vessels in the lungs, resulting in pulmonary hypertension. When this happens (often before one year of life) the patient becomes blue, and it’s often too late to do successful surgery. […] If the pulmonary valve has significant leakage or blockage, symptoms could develop (including exercise intolerance and heart rhythm issues). […] Sometimes, even when the defect is repaired early, pulmonary hypertension becomes progressively worse. Patients may experience shortness of breath, decreased exercise endurance and sometimes headaches and dizziness.

• #20 Truncus Arteriosus: Symptoms & Causes | NewYork-Presbyterian

  https://www.nyp.org/pediatrics/heart/truncus-arteriosus

  Heart failure. Symptoms and signs of truncus arteriosus in adults can include: Shortness of breath, especially during physical activity […] Fatigue. Most people born with truncus arteriosus require surgery during infancy. Although there are rare cases where a person may survive into adulthood without surgical repair of the heart, they almost always develop future heart failure and pulmonary hypertension.

• #21 Truncus Arteriosus (TA) – Stanford Medicine Children’s Health

  https://www.stanfordchildrens.org/en/topic/default?id=truncus-arteriosus-ta-90-P01826

  Symptoms of truncus arteriosus include: Bluish color to the skin, lips, and nails (cyanosis) […] Problems breathing […] Poor feeding or eating […] Tiredness (fatigue) […] Enlarged liver […] Extreme sleepiness. The symptoms of truncus arteriosus can be like other health conditions. Have your child see his or her healthcare provider for a diagnosis. […] If not treated, truncus arteriosus may cause complications such as: Lung damage […] Heart failure […] Infection of the lining of the heart and heart valves (bacterial endocarditis) […] Poor growth and development […] Diminished ability to function […] Easily tired […] Death. […] Soon after surgery, babies have more energy and start to eat better and gain weight faster. But your baby may need high-calorie formula for several weeks or months after surgery. Your baby may also need tube feedings until he or she is able to feed better.

• #22 Truncus Arteriosus (TA) – Stanford Medicine Children’s Health

  https://www.stanfordchildrens.org/en/topic/default?id=truncus-arteriosus-ta-90-P01826

  Your baby may become tired easily, and sleep more right after surgery. But within a few weeks, he or she should be fully recovered. […] Most children who have had truncus arteriosus surgical repair will live healthy lives. Their activity levels, appetite, and growth will usually return to normal. […] Your child most likely will need more surgery as he or she grows. Surgery in young adulthood may also be needed. These surgeries may involve replacing valves, repairing a narrowed aorta or pulmonary arteries, or replacing conduits. […] Call your child’s healthcare provider if your child has trouble breathing or feeding, or develops new symptoms. […] Truncus arteriosus must be treated with surgery. […] Most children who have had truncus arteriosus surgical repair will live healthy lives. […] Your child will need regular follow-up care with a pediatric cardiologist.

• #23 Truncus Arteriosus (TA) | University Hospitals

  https://www.uhhospitals.org/health-information/health-and-wellness-library/article/Diseases-and-Conditions—Pediatrics/truncus-arteriosus

  Symptoms of truncus arteriosus include: […] The symptoms of truncus arteriosus can be like other health conditions. Have your child see their healthcare provider for a diagnosis. […] If not treated, truncus arteriosus may cause complications, such as: […] Soon after surgery, babies have more energy and start to eat better and gain weight faster. But your baby may need high-calorie formula for several weeks or months after surgery. Your baby may also need tube feedings until they are able to feed better. […] Your baby may become tired easily, and sleep more right after surgery. But in a few weeks, they should be fully recovered. […] Most children who have had truncus arteriosus surgical repair will live healthy lives. Their activity levels, appetite, and growth will often return to normal. […] Your child most likely will need more surgery and/or cardiac catheterization procedures as they grow. Surgery in young adulthood may also be needed. […] Call your child’s healthcare provider if your child has trouble breathing or feeding, or develops new symptoms.

• #24

  https://www.pted.org/?id=truncusarteriosus4

  This defect almost always requires treatment in early life. Early symptoms are usually severe and include sweating, rapid breathing, inability to feed, arrhythmias (abnormal heart beats), mild cyanosis (blueness), and congestive heart failure. […] In the absence of treatment, these symptoms, or others that may develop somewhat later, such as pulmonary vascular disease, will almost always prove fatal in early childhood. […] Another later complication with this defect is dysfunction (regurgitation) of the aortic (truncal) valve, even after repair. A valve replacement operation may eventually be needed. […] The Truncus Arteriosus patient should be monitored regularly to guard against the development of complications or new symptoms. […] Despite the variety of late complications after surgery for this defect, the long-term prognosis is good and improving.

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