Materiały źródłowe

• #1 Pediatric Neuroblastoma Treatment & Management: Medical Care, Cooperative Group Treatment Strategies, Surgical Care

  https://emedicine.medscape.com/article/988284-treatment

  Care of children with neuroblastoma is provided by a multidisciplinary team involving pediatric oncology, radiation oncologists, surgeons, and anesthesiologists, as well as nurse practitioners, nurses, pharmacists, psychologists, and physical and occupational therapists dedicated to the special needs of these children. […] Surgical resection plays an important role in the treatment of patients with neuroblastoma. For patients with localized disease, surgical resection is curative. For patients with regional or metastatic disease, surgery to establish a diagnosis and obtain adequate samples for biologic studies is essential. Typically, second-look surgery postchemotherapy is used to attempt a complete resection. The emphasis in the second-look procedure is as complete a debulking as possible without sacrificing major organ function. Patients with residual disease postchemotherapy and surgery may benefit from the use of radiotherapy.

• #2 Neuroblastoma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/neuroblastoma/diagnosis-treatment/drc-20351022

  Our caring team of Mayo Clinic experts can help you with your neuroblastoma-related health concerns […] Neuroblastoma care at Mayo Clinic […] Treatments for neuroblastoma include surgery, radiation therapy, and medicines, such as chemotherapy and others. […] The healthcare team uses this information to say whether the neuroblastoma is low risk, intermediate risk or high risk. […] Neuroblastoma that is low risk or intermediate risk has a good chance for cure. […] High risk neuroblastoma can be more difficult to cure, so stronger treatments might be needed. […] During surgery for neuroblastoma, surgeons use cutting tools to remove the cancer cells. […] In children with low-risk neuroblastoma, surgery to remove the cancer may be the only treatment needed. […] In intermediate-risk and high-risk neuroblastoma, surgeons may try to remove as much of the cancer as possible.

• #3 Treating Neuroblastoma | Neuroblastoma Treatment | American Cancer Society

  https://www.cancer.org/cancer/types/neuroblastoma/treating.html

  If your child has been diagnosed with neuroblastoma, the cancer care team will discuss treatment options with you. Its important to consider both the benefits of each treatment option and the possible risks and side effects. […] Treatment of neuroblastoma depends on the risk group of the cancer, the childs age, and other factors, and might include more than one type of treatment. […] Children with neuroblastoma and their families have special needs that can best be met by children’s cancer centers. These centers have teams of specialists who understand the differences between cancers in adults and those in children, as well as the unique needs of younger people with cancer. […] Treating neuroblastoma is complex and often requires a team approach that includes many different doctors, nurses, and other health professionals.

• #4 Treating Neuroblastoma | Neuroblastoma Treatment | American Cancer Society

  https://www.cancer.org/cancer/types/neuroblastoma/treating.html

  If your child has been diagnosed with neuroblastoma, the cancer care team will discuss treatment options with you. Its important to consider both the benefits of each treatment option and the possible risks and side effects. […] Treatment of neuroblastoma depends on the risk group of the cancer, the childs age, and other factors, and might include more than one type of treatment. […] Children with neuroblastoma and their families have special needs that can best be met by children’s cancer centers. These centers have teams of specialists who understand the differences between cancers in adults and those in children, as well as the unique needs of younger people with cancer. […] Treating neuroblastoma is complex and often requires a team approach that includes many different doctors, nurses, and other health professionals.

• #5 Neuroblastoma Treatment | St. Jude Care & Treatment

  https://www.stjude.org/care-treatment/treatment/childhood-cancer/solid-tumors/neuroblastoma.html

  St. Jude provides the highest quality of care for patients with neuroblastoma: […] The nurse-to-patient ratio at St. Jude is about 1:3 in hematology and oncology and 1:1 in the Intensive Care Unit. […] Patients may be able to get expert, compassionate care and treatment closer to their homes through the St. Jude Affiliate Program.

• #6 Neuroblastoma Treatment – NCI

  https://www.cancer.gov/types/neuroblastoma/patient/neuroblastoma-treatment-pdq

  Neuroblastoma is a type of cancer that forms in neuroblasts (immature nerve tissue) in the adrenal glands, neck, chest, or spinal cord. […] Neuroblastoma most often begins in infancy. It is usually diagnosed between the first month of life and age 5 years. The tumor is found when it begins to grow and cause signs or symptoms. […] Signs and symptoms of neuroblastoma include bone pain or a lump in the abdomen, neck, or chest. […] Tests that examine many different body tissues and fluids are used to diagnose neuroblastoma. […] Children with certain gene mutations or hereditary (inherited) syndromes should be checked for signs of neuroblastoma until they are 10 years old. […] Treatment of neuroblastoma is based on risk groups. […] Children with neuroblastoma should have their treatment planned by a team of doctors who are experts in treating childhood cancer, especially neuroblastoma.

• #7 Childhood Neuroblastoma – UChicago Medicine Comer Children’s – UChicago Medicine

  https://www.uchicagomedicine.org/comer/conditions-services/pediatric-cancer/neuroblastoma

  Childhood neuroblastoma is a solid, cancerous tumor that begins in the sympathetic nervous system. This type of tumor often is found in the abdomen, but can also be located in the neck, chest and/or pelvis. Most children with neuroblastoma are diagnosed before the age of five. […] The Neuroblastoma Program at the University of Chicago Medicine Comer Children’s Hospital is led by Susan Cohn, MD, one of the nation’s foremost authorities on neuroblastoma. Under Dr. Cohn’s leadership, a team of pediatric cancer experts provides comprehensive diagnoses and a wide range of advanced treatment options. […] Neuroblastoma grows and reacts differently to treatment in different patients. By using a combination of factors, doctors usually can predict how clinically aggressive the tumor will be and tailor treatments accordingly. Clinical, pathologic and genetic markers are used to predict the clinical behavior of the tumor, how it will respond to treatment and survival. These factors are used to assign patients to risk groups (low, intermediate or high) and guide treatment decisions.

• #8 Neuroblastoma Treatment | American Cancer Society

  https://www.cancer.org/cancer/types/neuroblastoma/treating/by-risk-group.html

  Treatment for neuroblastoma is largely based on which risk group a child is in. Generally, younger children with smaller tumors are in the lower risk groups, while older children, children with tumors that have spread throughout the body, and children whose tumors have unfavorable features or extra copies of the MYCN gene are in the high-risk group. […] Children at low risk usually dont need very intensive treatment to cure the neuroblastoma. In fact, some children (especially young infants with small tumors) might not need to be treated at all because some of these neuroblastomas will mature or go away on their own. […] Surgery is an important part of treatment for children at intermediate risk, but it is rarely enough on its own. […] Children at high risk require more aggressive treatment, which often includes chemotherapy, surgery, radiation, stem cell transplant, immunotherapy, and retinoid therapy. […] If neuroblastoma comes back after initial treatment, it is known as a recurrence or relapse. Treatment of recurrent neuroblastoma depends on many factors, including the initial risk group, where the cancer recurs, and what treatments have been used.

• #9 Neuroblastoma Treatment | American Cancer Society

  https://www.cancer.org/cancer/types/neuroblastoma/treating/by-risk-group.html

  Treatment for neuroblastoma is largely based on which risk group a child is in. Generally, younger children with smaller tumors are in the lower risk groups, while older children, children with tumors that have spread throughout the body, and children whose tumors have unfavorable features or extra copies of the MYCN gene are in the high-risk group. […] Children at low risk usually dont need very intensive treatment to cure the neuroblastoma. In fact, some children (especially young infants with small tumors) might not need to be treated at all because some of these neuroblastomas will mature or go away on their own. […] Surgery is an important part of treatment for children at intermediate risk, but it is rarely enough on its own. […] Children at high risk require more aggressive treatment, which often includes chemotherapy, surgery, radiation, stem cell transplant, immunotherapy, and retinoid therapy. […] If neuroblastoma comes back after initial treatment, it is known as a recurrence or relapse. Treatment of recurrent neuroblastoma depends on many factors, including the initial risk group, where the cancer recurs, and what treatments have been used.

• #10 Neuroblastoma Treatment | American Cancer Society

  https://www.cancer.org/cancer/types/neuroblastoma/treating/by-risk-group.html

  Treatment for neuroblastoma is largely based on which risk group a child is in. Generally, younger children with smaller tumors are in the lower risk groups, while older children, children with tumors that have spread throughout the body, and children whose tumors have unfavorable features or extra copies of the MYCN gene are in the high-risk group. […] Children at low risk usually dont need very intensive treatment to cure the neuroblastoma. In fact, some children (especially young infants with small tumors) might not need to be treated at all because some of these neuroblastomas will mature or go away on their own. […] Surgery is an important part of treatment for children at intermediate risk, but it is rarely enough on its own. […] Children at high risk require more aggressive treatment, which often includes chemotherapy, surgery, radiation, stem cell transplant, immunotherapy, and retinoid therapy. […] If neuroblastoma comes back after initial treatment, it is known as a recurrence or relapse. Treatment of recurrent neuroblastoma depends on many factors, including the initial risk group, where the cancer recurs, and what treatments have been used.

• #11 Treating Neuroblastoma | Neuroblastoma Treatment | American Cancer Society

  https://www.cancer.org/cancer/types/neuroblastoma/treating.html

  Your childs cancer care team will discuss the treatment options with you. Its important to discuss these options and their possible side effects with your childs doctors so you can make an informed decision. […] Before treatment, the doctors and other members of the team will help you, as a parent, understand the tests that will need to be done. […] Your child’s cancer care team will be your first source of information and support, but there are other resources for help when you need it. Hospital- or clinic-based support services can also be an important part of your care. These might include nursing or social work services, financial aid, nutritional advice, rehab, or spiritual help. […] The treatment information given here is not official policy of the American Cancer Society and is not intended as medical advice to replace the expertise and judgment of your cancer care team. It is intended to help you and your family make informed decisions, together with your doctor.

• #12 Neuroblastoma | Causes, Symptoms, Diagnosis & Treatment

  https://www.cincinnatichildrens.org/health/n/neuroblastoma

  Neuroblastoma is the most common malignant (cancerous) extracranial solid tumor of childhood. It develops from the tissues that form the sympathetic nervous system, which is part of the nervous system that regulates involuntary body functions. […] Cancer cells can metastasize (spread) quickly to other areas of the body, such as lymph nodes, liver, lungs, bones, the central nervous system and bone marrow. Close to 70% of children diagnosed with neuroblastoma will have metastatic disease. […] Decisions about treatment plans should be made by parents and the child’s healthcare providers together. The treatment chosen should consider a number of factors: The child’s age, medical history and overall health; Extent of the disease; The child’s tolerance for specific medications, procedures or therapies.

• #13 Pediatric Neuroblastoma Treatment & Management: Medical Care, Cooperative Group Treatment Strategies, Surgical Care

  https://emedicine.medscape.com/article/988284-treatment

  Care of children with neuroblastoma is provided by a multidisciplinary team involving pediatric oncology, radiation oncologists, surgeons, and anesthesiologists, as well as nurse practitioners, nurses, pharmacists, psychologists, and physical and occupational therapists dedicated to the special needs of these children. […] Surgical resection plays an important role in the treatment of patients with neuroblastoma. For patients with localized disease, surgical resection is curative. For patients with regional or metastatic disease, surgery to establish a diagnosis and obtain adequate samples for biologic studies is essential. Typically, second-look surgery postchemotherapy is used to attempt a complete resection. The emphasis in the second-look procedure is as complete a debulking as possible without sacrificing major organ function. Patients with residual disease postchemotherapy and surgery may benefit from the use of radiotherapy.

• #14 Pediatric Neuroblastoma Treatment & Management: Medical Care, Cooperative Group Treatment Strategies, Surgical Care

  https://emedicine.medscape.com/article/988284-treatment

  Care of children with neuroblastoma is provided by a multidisciplinary team involving pediatric oncology, radiation oncologists, surgeons, and anesthesiologists, as well as nurse practitioners, nurses, pharmacists, psychologists, and physical and occupational therapists dedicated to the special needs of these children. […] Surgical resection plays an important role in the treatment of patients with neuroblastoma. For patients with localized disease, surgical resection is curative. For patients with regional or metastatic disease, surgery to establish a diagnosis and obtain adequate samples for biologic studies is essential. Typically, second-look surgery postchemotherapy is used to attempt a complete resection. The emphasis in the second-look procedure is as complete a debulking as possible without sacrificing major organ function. Patients with residual disease postchemotherapy and surgery may benefit from the use of radiotherapy.

• #15 Surgery for Neuroblastoma | NYU Langone Health

  https://nyulangone.org/conditions/neuroblastoma-in-children/treatments/surgery-for-neuroblastoma

  At Hassenfeld Childrens Hospital at NYU Langone, doctors sometimes perform surgery to remove a neuroblastoma. This may be the only treatment required, particularly for children under 18 months or those with cancer that has not spread. […] Children with high-risk neuroblastomas, which grow quickly and are more likely to return after treatment, require more aggressive therapies. In this case, doctors may use a combination of surgery, chemotherapy, radiation therapy, or stem cell transplantation. […] The goal of surgery is to remove as much of the tumor as possible. Sometimes, the entire tumor can be removed, leading to remissionan absence of cancer cells in the body. […] Surgery to remove a neuroblastoma can be complicated, because the tumors are frequently located near blood vessels that supply blood to vital organs, such as the kidneys or stomach. If the tumor is entangled with large blood vessels or pressed against vital organs or the spinal cord, removing the entire tumor could damage healthy tissue and organs.

• #16 Surgery for Neuroblastoma | NYU Langone Health

  https://nyulangone.org/conditions/neuroblastoma-in-children/treatments/surgery-for-neuroblastoma

  In these situations, parts of the tumor may be left in the body after surgery, and additional treatmentssuch as chemotherapy or, less frequently, radiationmay be necessary. Sometimes, a second surgery is performed to evaluate the success of these treatments and to remove the remaining tumor. […] During surgery, doctors also remove nearby lymph nodessmall vessels located throughout the body that filter fluid from tissue and assist in trapping viruses and bacteriawhich are then examined for cancer cells under a microscope. Lymph nodes are often the first place a cancer may spread. If cancer is found in the lymph nodes, additional therapies may be needed to eliminate neuroblastoma cells throughout the body. […] Complications of surgery for neuroblastoma depend on the tumors size, location, or aggressiveness, meaning how quickly it grows and spreadsas well as the childs age and health at diagnosis. The side effects of surgery can include damage to blood vessels or organs near the tumor. Our doctors take care to minimize any side effects of neuroblastoma surgery, and provide additional treatment when they cant be avoided. […] Your childs oncologist, surgeon, and other specialists provide support to help your family manage the physical and emotional effects of surgery for neuroblastoma.

• #17 Pediatric Neuroblastoma Treatment & Management: Medical Care, Cooperative Group Treatment Strategies, Surgical Care

  https://emedicine.medscape.com/article/988284-treatment

  Care of children with neuroblastoma is provided by a multidisciplinary team involving pediatric oncology, radiation oncologists, surgeons, and anesthesiologists, as well as nurse practitioners, nurses, pharmacists, psychologists, and physical and occupational therapists dedicated to the special needs of these children. […] Surgical resection plays an important role in the treatment of patients with neuroblastoma. For patients with localized disease, surgical resection is curative. For patients with regional or metastatic disease, surgery to establish a diagnosis and obtain adequate samples for biologic studies is essential. Typically, second-look surgery postchemotherapy is used to attempt a complete resection. The emphasis in the second-look procedure is as complete a debulking as possible without sacrificing major organ function. Patients with residual disease postchemotherapy and surgery may benefit from the use of radiotherapy.

• #18 Pediatric Neuroblastoma Treatment & Management: Medical Care, Cooperative Group Treatment Strategies, Surgical Care

  https://emedicine.medscape.com/article/988284-treatment

  Care of children with neuroblastoma is provided by a multidisciplinary team involving pediatric oncology, radiation oncologists, surgeons, and anesthesiologists, as well as nurse practitioners, nurses, pharmacists, psychologists, and physical and occupational therapists dedicated to the special needs of these children. […] Surgical resection plays an important role in the treatment of patients with neuroblastoma. For patients with localized disease, surgical resection is curative. For patients with regional or metastatic disease, surgery to establish a diagnosis and obtain adequate samples for biologic studies is essential. Typically, second-look surgery postchemotherapy is used to attempt a complete resection. The emphasis in the second-look procedure is as complete a debulking as possible without sacrificing major organ function. Patients with residual disease postchemotherapy and surgery may benefit from the use of radiotherapy.

• #19 Neuroblastoma | Causes, Symptoms, Diagnosis & Treatment

  https://www.cincinnatichildrens.org/health/n/neuroblastoma

  Treatment includes a wide range of approaches. Depending on individual circumstances, one or more of these approaches are used either alone or in combination: Surgery to remove the primary tumor (the main or first tumor, if there are more than one); Chemotherapy; Radiation therapy; Blood and marrow transplant; Immunotherapy. […] Each treatment has both benefits and side effects. Your child’s doctors will closely monitor side effects and give supportive care. Antibiotics may be prescribed to prevent or treat infections. […] The goal of surgery is to remove as much of the tumor as possible. Partial removal may be needed if the tumor is unable to be separated from vital structures (such as blood vessels or nerves). […] After surgery, most children stay in the hospital for several days. The length of the stay depends on the extent of the surgery and how quickly they recover. […] Continuous follow-up care is crucial. Regular monitoring helps track a child’s response to treatment, potential effects, and any disease recurrence. Ongoing care allows healthcare providers to adjust treatment plans as needed.

• #20 The Role of Nursing Professionals in the Management of Patients With High-Risk Neuroblastoma Receiving Dinutuximab Therapy

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7523913/

  Neuroblastoma, an embryonic cancer of the sympathetic nervous system, is the most common extracranial solid tumor in childhood. […] However, the safe and effective use of dinutuximab therapy in these high-risk patients requires medical expertise in patient selection, treatment administration, and the monitoring and management of adverse events. […] Multi-institutional nursing approaches to implementing standard protocols ensure the effective management of high-risk neuroblastoma patients receiving dinutuximab immunotherapy. […] Understanding and implementing recommendations for the management of the clinically important and most common adverse events are essential to ensuring patient continuation of therapy and improving patient outcomes. […] Nurses, as key members of the multidisciplinary team managing patients with high-risk neuroblastoma, play a critical role in administering therapy, managing AEs, and educating patients and families.

• #21 The Role of Nursing Professionals in the Management of Patients With High-Risk Neuroblastoma Receiving Dinutuximab Therapy

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7523913/

  The expert assessment and management of AEs, as well as preparation of and collaboration with patients and families, will facilitate patients remaining on therapy and receiving the full cycle of treatment, thereby optimizing the possibility of long-term control. […] The critical and diverse roles of the nurse should not be underestimated and include responsibilities of patient education, pretreatment planning, monitoring during therapy, early AE identification, and safe treatment when AEs occur. […] As the use of dinutuximab in the treatment of high-risk neuroblastoma expands, astute assessment and management of treatment-related AEs will be fundamental to improving patient adherence to therapy and outcomes.

• #22 Pediatric Neuroblastoma Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications

  https://emedicine.medscape.com/article/988284-followup

  Patients are periodically monitored in the clinic after each course of therapy to monitor for complications and to assess response to therapy with diagnostic imaging. Myelosuppression and pancytopenia are common complications, and a CBC count with platelet count is obtained as often as twice per week. Some drugs (eg, cisplatin, carboplatin, ifosfamide) affect renal function; thus, close monitoring of electrolytes is required, with oral electrolyte supplementation when necessary. Blood product support is provided when the hemoglobin drops to less than 8 g/dL, the platelet count drops to less than 10,000, or any signs of bleeding are present. […] After completion of therapy, successfully treated patients require follow-up care and close surveillance for any signs or symptoms of recurrent disease. Follow-up care includes monitoring of urinary catecholamines, physical examination, and diagnostic imaging. Because most recurrences occur during the first 2 years following treatment, most protocols recommend close follow-up care during this interval. […] Patients who remain free of recurrent disease for 5 years are considered cured, although rare late relapses have been reported. Long-term follow-up care to assess impact of therapy on growth, development, and organ toxicity is essential.

• #23 Pediatric Neuroblastoma Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications

  https://emedicine.medscape.com/article/988284-followup

  Patients are periodically monitored in the clinic after each course of therapy to monitor for complications and to assess response to therapy with diagnostic imaging. Myelosuppression and pancytopenia are common complications, and a CBC count with platelet count is obtained as often as twice per week. Some drugs (eg, cisplatin, carboplatin, ifosfamide) affect renal function; thus, close monitoring of electrolytes is required, with oral electrolyte supplementation when necessary. Blood product support is provided when the hemoglobin drops to less than 8 g/dL, the platelet count drops to less than 10,000, or any signs of bleeding are present. […] After completion of therapy, successfully treated patients require follow-up care and close surveillance for any signs or symptoms of recurrent disease. Follow-up care includes monitoring of urinary catecholamines, physical examination, and diagnostic imaging. Because most recurrences occur during the first 2 years following treatment, most protocols recommend close follow-up care during this interval. […] Patients who remain free of recurrent disease for 5 years are considered cured, although rare late relapses have been reported. Long-term follow-up care to assess impact of therapy on growth, development, and organ toxicity is essential.

• #24 Pediatric Neuroblastoma Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications

  https://emedicine.medscape.com/article/988284-followup

  Patients are periodically monitored in the clinic after each course of therapy to monitor for complications and to assess response to therapy with diagnostic imaging. Myelosuppression and pancytopenia are common complications, and a CBC count with platelet count is obtained as often as twice per week. Some drugs (eg, cisplatin, carboplatin, ifosfamide) affect renal function; thus, close monitoring of electrolytes is required, with oral electrolyte supplementation when necessary. Blood product support is provided when the hemoglobin drops to less than 8 g/dL, the platelet count drops to less than 10,000, or any signs of bleeding are present. […] After completion of therapy, successfully treated patients require follow-up care and close surveillance for any signs or symptoms of recurrent disease. Follow-up care includes monitoring of urinary catecholamines, physical examination, and diagnostic imaging. Because most recurrences occur during the first 2 years following treatment, most protocols recommend close follow-up care during this interval. […] Patients who remain free of recurrent disease for 5 years are considered cured, although rare late relapses have been reported. Long-term follow-up care to assess impact of therapy on growth, development, and organ toxicity is essential.

• #25 Pediatric Neuroblastoma Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications

  https://emedicine.medscape.com/article/988284-followup

  Patients are periodically monitored in the clinic after each course of therapy to monitor for complications and to assess response to therapy with diagnostic imaging. Myelosuppression and pancytopenia are common complications, and a CBC count with platelet count is obtained as often as twice per week. Some drugs (eg, cisplatin, carboplatin, ifosfamide) affect renal function; thus, close monitoring of electrolytes is required, with oral electrolyte supplementation when necessary. Blood product support is provided when the hemoglobin drops to less than 8 g/dL, the platelet count drops to less than 10,000, or any signs of bleeding are present. […] After completion of therapy, successfully treated patients require follow-up care and close surveillance for any signs or symptoms of recurrent disease. Follow-up care includes monitoring of urinary catecholamines, physical examination, and diagnostic imaging. Because most recurrences occur during the first 2 years following treatment, most protocols recommend close follow-up care during this interval. […] Patients who remain free of recurrent disease for 5 years are considered cured, although rare late relapses have been reported. Long-term follow-up care to assess impact of therapy on growth, development, and organ toxicity is essential.

• #26 Pediatric Neuroblastoma Treatment & Management: Medical Care, Cooperative Group Treatment Strategies, Surgical Care

  https://emedicine.medscape.com/article/988284-treatment

  Nutrition plays an important role in therapy. Children need adequate caloric intake to attain normal growth and development, and to recover from the adverse effects of therapy. Nutritionists typically help to provide adequate supportive care during therapy. Supplemental nutrition is often required during therapy. This should occur via the enteral route (nasogastric or gastric tube). The parenteral route should be used only after failure to supplement adequately using enteral feedings. […] No specific restrictions are placed on activity. Patients who are thrombocytopenic should avoid strenuous activity and contact sports. Patients should avoid ill contacts, especially if neutropenic.

• #27 Pediatric Neuroblastoma Treatment & Management: Medical Care, Cooperative Group Treatment Strategies, Surgical Care

  https://emedicine.medscape.com/article/988284-treatment

  Nutrition plays an important role in therapy. Children need adequate caloric intake to attain normal growth and development, and to recover from the adverse effects of therapy. Nutritionists typically help to provide adequate supportive care during therapy. Supplemental nutrition is often required during therapy. This should occur via the enteral route (nasogastric or gastric tube). The parenteral route should be used only after failure to supplement adequately using enteral feedings. […] No specific restrictions are placed on activity. Patients who are thrombocytopenic should avoid strenuous activity and contact sports. Patients should avoid ill contacts, especially if neutropenic.

• #28 Neuroblastoma Supportive Care | Diet & Nutrition

  https://www.neuroblastoma-info.com/supportive-care/diet-nutrition/

  A decrease in your child’s appetite during treatment can keep them from getting the nutrients they need. Ensuring they receive adequate nutrition will be important because it helps support growth and healing throughout the neuroblastoma journey. […] Because decreased appetite and weight loss are common during neuroblastoma treatment, your child’s healthcare team will follow your child’s growth (height and weight) regularly. A registered dietitian may work with you and your child to help them maintain or gain weight when necessary. […] Despite everyone’s best efforts, your child may still lose weight during treatment. If the healthcare team determines weight loss is a concern, nutritional supplements or appetite stimulants may be suggested. […] Feeding tubes can be used throughout treatment to help support your child’s nutrition. […] TPN is usually a short-term method of nutrition until your child is able to eat normally again. TPN may be used during stem cell transplantation.

• #29 Neuroblastoma Supportive Care | Diet & Nutrition

  https://www.neuroblastoma-info.com/supportive-care/diet-nutrition/

  A decrease in your child’s appetite during treatment can keep them from getting the nutrients they need. Ensuring they receive adequate nutrition will be important because it helps support growth and healing throughout the neuroblastoma journey. […] Because decreased appetite and weight loss are common during neuroblastoma treatment, your child’s healthcare team will follow your child’s growth (height and weight) regularly. A registered dietitian may work with you and your child to help them maintain or gain weight when necessary. […] Despite everyone’s best efforts, your child may still lose weight during treatment. If the healthcare team determines weight loss is a concern, nutritional supplements or appetite stimulants may be suggested. […] Feeding tubes can be used throughout treatment to help support your child’s nutrition. […] TPN is usually a short-term method of nutrition until your child is able to eat normally again. TPN may be used during stem cell transplantation.

• #30 Neuroblastoma Supportive Care | Diet & Nutrition

  https://www.neuroblastoma-info.com/supportive-care/diet-nutrition/

  A decrease in your child’s appetite during treatment can keep them from getting the nutrients they need. Ensuring they receive adequate nutrition will be important because it helps support growth and healing throughout the neuroblastoma journey. […] Because decreased appetite and weight loss are common during neuroblastoma treatment, your child’s healthcare team will follow your child’s growth (height and weight) regularly. A registered dietitian may work with you and your child to help them maintain or gain weight when necessary. […] Despite everyone’s best efforts, your child may still lose weight during treatment. If the healthcare team determines weight loss is a concern, nutritional supplements or appetite stimulants may be suggested. […] Feeding tubes can be used throughout treatment to help support your child’s nutrition. […] TPN is usually a short-term method of nutrition until your child is able to eat normally again. TPN may be used during stem cell transplantation.

• #31 Neuroblastoma Supportive Care | Diet & Nutrition

  https://www.neuroblastoma-info.com/supportive-care/diet-nutrition/

  A decrease in your child’s appetite during treatment can keep them from getting the nutrients they need. Ensuring they receive adequate nutrition will be important because it helps support growth and healing throughout the neuroblastoma journey. […] Because decreased appetite and weight loss are common during neuroblastoma treatment, your child’s healthcare team will follow your child’s growth (height and weight) regularly. A registered dietitian may work with you and your child to help them maintain or gain weight when necessary. […] Despite everyone’s best efforts, your child may still lose weight during treatment. If the healthcare team determines weight loss is a concern, nutritional supplements or appetite stimulants may be suggested. […] Feeding tubes can be used throughout treatment to help support your child’s nutrition. […] TPN is usually a short-term method of nutrition until your child is able to eat normally again. TPN may be used during stem cell transplantation.

• #32 Pediatric Neuroblastoma Treatment & Management: Medical Care, Cooperative Group Treatment Strategies, Surgical Care

  https://emedicine.medscape.com/article/988284-treatment

  Nutrition plays an important role in therapy. Children need adequate caloric intake to attain normal growth and development, and to recover from the adverse effects of therapy. Nutritionists typically help to provide adequate supportive care during therapy. Supplemental nutrition is often required during therapy. This should occur via the enteral route (nasogastric or gastric tube). The parenteral route should be used only after failure to supplement adequately using enteral feedings. […] No specific restrictions are placed on activity. Patients who are thrombocytopenic should avoid strenuous activity and contact sports. Patients should avoid ill contacts, especially if neutropenic.

• #33 Neuroblastoma – Diagnosis & Disease Information

  https://www.cancertherapyadvisor.com/ddi/neuroblastoma/

  Radiation therapy is typically used in high-risk neuroblastoma cases, particularly when surgical resection is incomplete or when there is residual disease after chemotherapy and surgery. It can also be used to treat metastatic sites and to ease symptoms in advanced stages of the disease. […] Immunotherapy has emerged as an important component of neuroblastoma treatment. Anti-GD2 monoclonal antibodies, such as dinutuximab and naxitamab, are used to target neuroblastoma cells. This treatment is often combined with cytokines such as interleukin-2 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to enhance the immune response against cancer cells. […] Healthcare providers must be vigilant in monitoring patients for potential adverse effects and drug interactions associated with the various treatments used for neuroblastoma.

• #34 Neuroblastoma – Diagnosis & Disease Information

  https://www.cancertherapyadvisor.com/ddi/neuroblastoma/

  Radiation therapy is typically used in high-risk neuroblastoma cases, particularly when surgical resection is incomplete or when there is residual disease after chemotherapy and surgery. It can also be used to treat metastatic sites and to ease symptoms in advanced stages of the disease. […] Immunotherapy has emerged as an important component of neuroblastoma treatment. Anti-GD2 monoclonal antibodies, such as dinutuximab and naxitamab, are used to target neuroblastoma cells. This treatment is often combined with cytokines such as interleukin-2 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to enhance the immune response against cancer cells. […] Healthcare providers must be vigilant in monitoring patients for potential adverse effects and drug interactions associated with the various treatments used for neuroblastoma.

• #35 The Role of Nursing Professionals in the Management of Patients With High-Risk Neuroblastoma Receiving Dinutuximab Therapy

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7523913/

  Neuroblastoma, an embryonic cancer of the sympathetic nervous system, is the most common extracranial solid tumor in childhood. […] However, the safe and effective use of dinutuximab therapy in these high-risk patients requires medical expertise in patient selection, treatment administration, and the monitoring and management of adverse events. […] Multi-institutional nursing approaches to implementing standard protocols ensure the effective management of high-risk neuroblastoma patients receiving dinutuximab immunotherapy. […] Understanding and implementing recommendations for the management of the clinically important and most common adverse events are essential to ensuring patient continuation of therapy and improving patient outcomes. […] Nurses, as key members of the multidisciplinary team managing patients with high-risk neuroblastoma, play a critical role in administering therapy, managing AEs, and educating patients and families.

• #36 The Role of Nursing Professionals in the Management of Patients With High-Risk Neuroblastoma Receiving Dinutuximab Therapy

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7523913/

  Neuroblastoma, an embryonic cancer of the sympathetic nervous system, is the most common extracranial solid tumor in childhood. […] However, the safe and effective use of dinutuximab therapy in these high-risk patients requires medical expertise in patient selection, treatment administration, and the monitoring and management of adverse events. […] Multi-institutional nursing approaches to implementing standard protocols ensure the effective management of high-risk neuroblastoma patients receiving dinutuximab immunotherapy. […] Understanding and implementing recommendations for the management of the clinically important and most common adverse events are essential to ensuring patient continuation of therapy and improving patient outcomes. […] Nurses, as key members of the multidisciplinary team managing patients with high-risk neuroblastoma, play a critical role in administering therapy, managing AEs, and educating patients and families.

• #37 The Role of Nursing Professionals in the Management of Patients With High-Risk Neuroblastoma Receiving Dinutuximab Therapy

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7523913/

  The expert assessment and management of AEs, as well as preparation of and collaboration with patients and families, will facilitate patients remaining on therapy and receiving the full cycle of treatment, thereby optimizing the possibility of long-term control. […] The critical and diverse roles of the nurse should not be underestimated and include responsibilities of patient education, pretreatment planning, monitoring during therapy, early AE identification, and safe treatment when AEs occur. […] As the use of dinutuximab in the treatment of high-risk neuroblastoma expands, astute assessment and management of treatment-related AEs will be fundamental to improving patient adherence to therapy and outcomes.

• #38 The Role of Nursing Professionals in the Management of Patients With High-Risk Neuroblastoma Receiving Dinutuximab Therapy

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7523913/

  Neuroblastoma, an embryonic cancer of the sympathetic nervous system, is the most common extracranial solid tumor in childhood. […] However, the safe and effective use of dinutuximab therapy in these high-risk patients requires medical expertise in patient selection, treatment administration, and the monitoring and management of adverse events. […] Multi-institutional nursing approaches to implementing standard protocols ensure the effective management of high-risk neuroblastoma patients receiving dinutuximab immunotherapy. […] Understanding and implementing recommendations for the management of the clinically important and most common adverse events are essential to ensuring patient continuation of therapy and improving patient outcomes. […] Nurses, as key members of the multidisciplinary team managing patients with high-risk neuroblastoma, play a critical role in administering therapy, managing AEs, and educating patients and families.

• #39 Neuroblastoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/neuroblastoma

  Supportive care for neuroblastoma helps children and their families meet physical, emotional and spiritual challenges.

• #40 Neuroblastoma

  https://www.nationwidechildrens.org/conditions/health-library/neuroblastoma

  Neuroblastoma Nursing, Care […] A child with a neuroblastoma needs ongoing care. Your child will be seen by oncologists and other healthcare providers to treat any late effects of treatment and to watch for signs or symptoms of the tumor returning. Imaging scans and other tests will be done. […] […] Your child may need therapy to help with movement and muscle strength. This may be done by physical and occupational therapists. […] […] You can help your child manage treatment in many ways. For instance: […] […] Get emotional support for your child. Find a counselor, psychologist, or child support group that can help. […] […] Make sure your child attends all follow-up appointments. […] […] Talk with your child’s healthcare provider about side effects linked with their treatment. Tell them about any changes you notice. There are often ways to manage side effects. There may be things your child can do and medicines they can take to help prevent or control many treatment side effects. […] […] Most side effects get better and go away over time after treatment ends. But some can last the rest of your child’s life. Talk to your child’s treatment team about what you can expect. […] […] Continuous follow-up care during and after treatment is needed.

• #41 Neuroblastoma

  https://www.nationwidechildrens.org/conditions/health-library/neuroblastoma

  Neuroblastoma Nursing, Care […] A child with a neuroblastoma needs ongoing care. Your child will be seen by oncologists and other healthcare providers to treat any late effects of treatment and to watch for signs or symptoms of the tumor returning. Imaging scans and other tests will be done. […] […] Your child may need therapy to help with movement and muscle strength. This may be done by physical and occupational therapists. […] […] You can help your child manage treatment in many ways. For instance: […] […] Get emotional support for your child. Find a counselor, psychologist, or child support group that can help. […] […] Make sure your child attends all follow-up appointments. […] […] Talk with your child’s healthcare provider about side effects linked with their treatment. Tell them about any changes you notice. There are often ways to manage side effects. There may be things your child can do and medicines they can take to help prevent or control many treatment side effects. […] […] Most side effects get better and go away over time after treatment ends. But some can last the rest of your child’s life. Talk to your child’s treatment team about what you can expect. […] […] Continuous follow-up care during and after treatment is needed.

• #42 Neuroblastoma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/neuroblastoma/diagnosis-treatment/drc-20351022

  Chemotherapy treats cancer with strong medicines. […] Children with intermediate-risk neuroblastoma often receive a combination of chemotherapy medicines before surgery. […] Children with high-risk neuroblastoma often receive high doses of chemotherapy medicines to shrink the cancer. […] Radiation therapy treats cancer with powerful energy beams. […] Children with high-risk neuroblastoma may receive radiation therapy after chemotherapy and surgery. […] A bone marrow transplant might be an option for children with high-risk neuroblastoma. […] Immunotherapy is a treatment with medicine that helps the body’s immune system kill cancer cells. […] Immunotherapy is sometimes used with chemotherapy for high-risk neuroblastoma. […] Seek out special resources for families of kids with cancer. […] Your family may be eligible for summer camps, temporary housing and other support. […] Ask your healthcare team about other ways to comfort your child through treatment.

• #43 Treatments for neuroblastoma | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/childrens-cancer/neuroblastoma/treatments

  Play specialists are often available to help your child get used to having radiotherapy. The team at your hospital are used to treating children with cancer. They will explain everything clearly to you, and to your child. […] The specialist team plan treatment based on several factors, including your childs age. Your child’s treatment depends on their risk group.

• #44 Treatments for neuroblastoma | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/childrens-cancer/neuroblastoma/treatments

  Play specialists are often available to help your child get used to having radiotherapy. The team at your hospital are used to treating children with cancer. They will explain everything clearly to you, and to your child. […] The specialist team plan treatment based on several factors, including your childs age. Your child’s treatment depends on their risk group.

• #45 Neuroblastoma Program | Children’s Healthcare of Atlanta

  https://www.choa.org/medical-services/cancer-and-blood-disorders/cancer/neuroblastoma-program

  Receiving a cancer diagnosis for your child can be an emotional and overwhelming experience. At the Aflac Cancer and Blood Disorders Center, we are here to support you and your family. We make it our mission to provide the best care and best experience for every child, whether treating a toddler during an emergency or helping a teen through chemotherapy treatments. Family plays an important role in your child’s well-being. Not only are you a vital part of your child’s healthcare team, you are a source of security and comfort for your child. […] We work to support your whole family while your child is in our care and after she goes home.

• #46 Neuroblastoma Program | Children’s Healthcare of Atlanta

  https://www.choa.org/medical-services/cancer-and-blood-disorders/cancer/neuroblastoma-program

  Receiving a cancer diagnosis for your child can be an emotional and overwhelming experience. At the Aflac Cancer and Blood Disorders Center, we are here to support you and your family. We make it our mission to provide the best care and best experience for every child, whether treating a toddler during an emergency or helping a teen through chemotherapy treatments. Family plays an important role in your child’s well-being. Not only are you a vital part of your child’s healthcare team, you are a source of security and comfort for your child. […] We work to support your whole family while your child is in our care and after she goes home.

• #47 Treating Neuroblastoma | Neuroblastoma Treatment | American Cancer Society

  https://www.cancer.org/cancer/types/neuroblastoma/treating.html

  Your childs cancer care team will discuss the treatment options with you. Its important to discuss these options and their possible side effects with your childs doctors so you can make an informed decision. […] Before treatment, the doctors and other members of the team will help you, as a parent, understand the tests that will need to be done. […] Your child’s cancer care team will be your first source of information and support, but there are other resources for help when you need it. Hospital- or clinic-based support services can also be an important part of your care. These might include nursing or social work services, financial aid, nutritional advice, rehab, or spiritual help. […] The treatment information given here is not official policy of the American Cancer Society and is not intended as medical advice to replace the expertise and judgment of your cancer care team. It is intended to help you and your family make informed decisions, together with your doctor.

• #48 Pediatric Neuroblastoma Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications

  https://emedicine.medscape.com/article/988284-followup

  Patients are periodically monitored in the clinic after each course of therapy to monitor for complications and to assess response to therapy with diagnostic imaging. Myelosuppression and pancytopenia are common complications, and a CBC count with platelet count is obtained as often as twice per week. Some drugs (eg, cisplatin, carboplatin, ifosfamide) affect renal function; thus, close monitoring of electrolytes is required, with oral electrolyte supplementation when necessary. Blood product support is provided when the hemoglobin drops to less than 8 g/dL, the platelet count drops to less than 10,000, or any signs of bleeding are present. […] After completion of therapy, successfully treated patients require follow-up care and close surveillance for any signs or symptoms of recurrent disease. Follow-up care includes monitoring of urinary catecholamines, physical examination, and diagnostic imaging. Because most recurrences occur during the first 2 years following treatment, most protocols recommend close follow-up care during this interval. […] Patients who remain free of recurrent disease for 5 years are considered cured, although rare late relapses have been reported. Long-term follow-up care to assess impact of therapy on growth, development, and organ toxicity is essential.

• #49 Pediatric Neuroblastoma Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications

  https://emedicine.medscape.com/article/988284-followup

  Patients are periodically monitored in the clinic after each course of therapy to monitor for complications and to assess response to therapy with diagnostic imaging. Myelosuppression and pancytopenia are common complications, and a CBC count with platelet count is obtained as often as twice per week. Some drugs (eg, cisplatin, carboplatin, ifosfamide) affect renal function; thus, close monitoring of electrolytes is required, with oral electrolyte supplementation when necessary. Blood product support is provided when the hemoglobin drops to less than 8 g/dL, the platelet count drops to less than 10,000, or any signs of bleeding are present. […] After completion of therapy, successfully treated patients require follow-up care and close surveillance for any signs or symptoms of recurrent disease. Follow-up care includes monitoring of urinary catecholamines, physical examination, and diagnostic imaging. Because most recurrences occur during the first 2 years following treatment, most protocols recommend close follow-up care during this interval. […] Patients who remain free of recurrent disease for 5 years are considered cured, although rare late relapses have been reported. Long-term follow-up care to assess impact of therapy on growth, development, and organ toxicity is essential.

• #50 Pediatric Neuroblastoma Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications

  https://emedicine.medscape.com/article/988284-followup

  Patients are periodically monitored in the clinic after each course of therapy to monitor for complications and to assess response to therapy with diagnostic imaging. Myelosuppression and pancytopenia are common complications, and a CBC count with platelet count is obtained as often as twice per week. Some drugs (eg, cisplatin, carboplatin, ifosfamide) affect renal function; thus, close monitoring of electrolytes is required, with oral electrolyte supplementation when necessary. Blood product support is provided when the hemoglobin drops to less than 8 g/dL, the platelet count drops to less than 10,000, or any signs of bleeding are present. […] After completion of therapy, successfully treated patients require follow-up care and close surveillance for any signs or symptoms of recurrent disease. Follow-up care includes monitoring of urinary catecholamines, physical examination, and diagnostic imaging. Because most recurrences occur during the first 2 years following treatment, most protocols recommend close follow-up care during this interval. […] Patients who remain free of recurrent disease for 5 years are considered cured, although rare late relapses have been reported. Long-term follow-up care to assess impact of therapy on growth, development, and organ toxicity is essential.

• #51 Pediatric Neuroblastoma Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications

  https://emedicine.medscape.com/article/988284-followup

  Patients are periodically monitored in the clinic after each course of therapy to monitor for complications and to assess response to therapy with diagnostic imaging. Myelosuppression and pancytopenia are common complications, and a CBC count with platelet count is obtained as often as twice per week. Some drugs (eg, cisplatin, carboplatin, ifosfamide) affect renal function; thus, close monitoring of electrolytes is required, with oral electrolyte supplementation when necessary. Blood product support is provided when the hemoglobin drops to less than 8 g/dL, the platelet count drops to less than 10,000, or any signs of bleeding are present. […] After completion of therapy, successfully treated patients require follow-up care and close surveillance for any signs or symptoms of recurrent disease. Follow-up care includes monitoring of urinary catecholamines, physical examination, and diagnostic imaging. Because most recurrences occur during the first 2 years following treatment, most protocols recommend close follow-up care during this interval. […] Patients who remain free of recurrent disease for 5 years are considered cured, although rare late relapses have been reported. Long-term follow-up care to assess impact of therapy on growth, development, and organ toxicity is essential.

• #52 Pediatric Neuroblastoma Follow-up: Further Outpatient Care, Further Inpatient Care, Inpatient & Outpatient Medications

  https://emedicine.medscape.com/article/988284-followup

  Patients are periodically monitored in the clinic after each course of therapy to monitor for complications and to assess response to therapy with diagnostic imaging. Myelosuppression and pancytopenia are common complications, and a CBC count with platelet count is obtained as often as twice per week. Some drugs (eg, cisplatin, carboplatin, ifosfamide) affect renal function; thus, close monitoring of electrolytes is required, with oral electrolyte supplementation when necessary. Blood product support is provided when the hemoglobin drops to less than 8 g/dL, the platelet count drops to less than 10,000, or any signs of bleeding are present. […] After completion of therapy, successfully treated patients require follow-up care and close surveillance for any signs or symptoms of recurrent disease. Follow-up care includes monitoring of urinary catecholamines, physical examination, and diagnostic imaging. Because most recurrences occur during the first 2 years following treatment, most protocols recommend close follow-up care during this interval. […] Patients who remain free of recurrent disease for 5 years are considered cured, although rare late relapses have been reported. Long-term follow-up care to assess impact of therapy on growth, development, and organ toxicity is essential.

• #53 Neuroblastoma

  https://www.nationwidechildrens.org/conditions/health-library/neuroblastoma

  Neuroblastoma Nursing, Care […] A child with a neuroblastoma needs ongoing care. Your child will be seen by oncologists and other healthcare providers to treat any late effects of treatment and to watch for signs or symptoms of the tumor returning. Imaging scans and other tests will be done. […] […] Your child may need therapy to help with movement and muscle strength. This may be done by physical and occupational therapists. […] […] You can help your child manage treatment in many ways. For instance: […] […] Get emotional support for your child. Find a counselor, psychologist, or child support group that can help. […] […] Make sure your child attends all follow-up appointments. […] […] Talk with your child’s healthcare provider about side effects linked with their treatment. Tell them about any changes you notice. There are often ways to manage side effects. There may be things your child can do and medicines they can take to help prevent or control many treatment side effects. […] […] Most side effects get better and go away over time after treatment ends. But some can last the rest of your child’s life. Talk to your child’s treatment team about what you can expect. […] […] Continuous follow-up care during and after treatment is needed.

• #54 Neuroblastoma – Seattle Children’s

  https://www.seattlechildrens.org/conditions/neuroblastoma/

  Our Cancer Survivor Program provides long-term follow-up care to help young people stay healthy after being treated for cancer in childhood. […] Year after year, our Cancer and Blood Disorders Center ranks among the nation’s best pediatric oncology programs by U.S. News World Report. The treatment of neuroblastoma requires very specific expertise in oncology, surgery, and radiation oncology. In addition to treating patients from the immediate Puget Sound area, Seattle Children’s serves as a neuroblastoma referral center for patients in the entire Pacific Northwest and beyond. […] Our specialty is treating disease while helping our patients grow up to be healthy and productive adults. […] A team of caring experts will focus on your whole child. We don’t just treat their cancer. […] We know that teens and young adults with cancer have different challenges than young children. Our Adolescent and Young Adult Cancer Program focuses on their needs, which may include fertility preservation.

• #55 Neuroblastoma – Seattle Children’s

  https://www.seattlechildrens.org/conditions/neuroblastoma/

  Our focus is helping your child beat their disease and thrive. Everyone in the Neuroblastoma Program works to cure your child’s disease, support your family during treatment, prevent serious side effects and provide follow-up care. […] Our experts are experienced in treating babies, children, teens and young adults with all risk levels and stages of neuroblastoma. Year after year, U.S. News World Report ranks our Cancer and Blood Disorder Center among the best pediatric oncology programs in the country. As leaders in neuroblastoma clinical care and research, we can offer advanced treatments that many centers do not provide. […] Follow-up care is important after treatment ends. The follow-up routine will depend on your child’s cancer and their treatments. Most of our patients visit every 3 to 12 months for 5 years.

• #56 Treating Neuroblastoma | Neuroblastoma Treatment | American Cancer Society

  https://www.cancer.org/cancer/types/neuroblastoma/treating.html

  Your childs cancer care team will discuss the treatment options with you. Its important to discuss these options and their possible side effects with your childs doctors so you can make an informed decision. […] Before treatment, the doctors and other members of the team will help you, as a parent, understand the tests that will need to be done. […] Your child’s cancer care team will be your first source of information and support, but there are other resources for help when you need it. Hospital- or clinic-based support services can also be an important part of your care. These might include nursing or social work services, financial aid, nutritional advice, rehab, or spiritual help. […] The treatment information given here is not official policy of the American Cancer Society and is not intended as medical advice to replace the expertise and judgment of your cancer care team. It is intended to help you and your family make informed decisions, together with your doctor.

• #57 Treating Neuroblastoma | Neuroblastoma Treatment | American Cancer Society

  https://www.cancer.org/cancer/types/neuroblastoma/treating.html

  Your childs cancer care team will discuss the treatment options with you. Its important to discuss these options and their possible side effects with your childs doctors so you can make an informed decision. […] Before treatment, the doctors and other members of the team will help you, as a parent, understand the tests that will need to be done. […] Your child’s cancer care team will be your first source of information and support, but there are other resources for help when you need it. Hospital- or clinic-based support services can also be an important part of your care. These might include nursing or social work services, financial aid, nutritional advice, rehab, or spiritual help. […] The treatment information given here is not official policy of the American Cancer Society and is not intended as medical advice to replace the expertise and judgment of your cancer care team. It is intended to help you and your family make informed decisions, together with your doctor.

• #58 Treating Neuroblastoma | Neuroblastoma Treatment | American Cancer Society

  https://www.cancer.org/cancer/types/neuroblastoma/treating.html

  Your childs cancer care team will discuss the treatment options with you. Its important to discuss these options and their possible side effects with your childs doctors so you can make an informed decision. […] Before treatment, the doctors and other members of the team will help you, as a parent, understand the tests that will need to be done. […] Your child’s cancer care team will be your first source of information and support, but there are other resources for help when you need it. Hospital- or clinic-based support services can also be an important part of your care. These might include nursing or social work services, financial aid, nutritional advice, rehab, or spiritual help. […] The treatment information given here is not official policy of the American Cancer Society and is not intended as medical advice to replace the expertise and judgment of your cancer care team. It is intended to help you and your family make informed decisions, together with your doctor.

• #59 Treatments for neuroblastoma | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/childrens-cancer/neuroblastoma/treatments

  Doctors plan your childs treatment in one of the major childrens cancer centres. Your child has most of their treatment in this specialist centre. They might have some care at a hospital closer to home. […] Children’s cancer centres have teams of specialists who know about neuroblastoma and the best way to treat them. […] Don’t be afraid to ask your doctor or specialist nurse any questions you have about the treatment. It helps to write down a list of questions you want to ask. Take a close friend or relative with you when you go to see them. And if your child is old enough and able you might want to encourage your child to ask questions too. […] Your childs doctor usually sees them every 6 weeks for the first few visits. The time between visits then gradually increases as the tumour gets smaller.

• #60 Neuroblastoma

  https://www.nationwidechildrens.org/conditions/health-library/neuroblastoma

  Neuroblastoma Nursing, Care […] A child with a neuroblastoma needs ongoing care. Your child will be seen by oncologists and other healthcare providers to treat any late effects of treatment and to watch for signs or symptoms of the tumor returning. Imaging scans and other tests will be done. […] […] Your child may need therapy to help with movement and muscle strength. This may be done by physical and occupational therapists. […] […] You can help your child manage treatment in many ways. For instance: […] […] Get emotional support for your child. Find a counselor, psychologist, or child support group that can help. […] […] Make sure your child attends all follow-up appointments. […] […] Talk with your child’s healthcare provider about side effects linked with their treatment. Tell them about any changes you notice. There are often ways to manage side effects. There may be things your child can do and medicines they can take to help prevent or control many treatment side effects. […] […] Most side effects get better and go away over time after treatment ends. But some can last the rest of your child’s life. Talk to your child’s treatment team about what you can expect. […] […] Continuous follow-up care during and after treatment is needed.

• #61 Neuroblastoma

  https://www.nationwidechildrens.org/conditions/health-library/neuroblastoma

  Neuroblastoma Nursing, Care […] A child with a neuroblastoma needs ongoing care. Your child will be seen by oncologists and other healthcare providers to treat any late effects of treatment and to watch for signs or symptoms of the tumor returning. Imaging scans and other tests will be done. […] […] Your child may need therapy to help with movement and muscle strength. This may be done by physical and occupational therapists. […] […] You can help your child manage treatment in many ways. For instance: […] […] Get emotional support for your child. Find a counselor, psychologist, or child support group that can help. […] […] Make sure your child attends all follow-up appointments. […] […] Talk with your child’s healthcare provider about side effects linked with their treatment. Tell them about any changes you notice. There are often ways to manage side effects. There may be things your child can do and medicines they can take to help prevent or control many treatment side effects. […] […] Most side effects get better and go away over time after treatment ends. But some can last the rest of your child’s life. Talk to your child’s treatment team about what you can expect. […] […] Continuous follow-up care during and after treatment is needed.

• #62 Neuroblastoma

  https://www.nationwidechildrens.org/conditions/health-library/neuroblastoma

  Neuroblastoma Nursing, Care […] A child with a neuroblastoma needs ongoing care. Your child will be seen by oncologists and other healthcare providers to treat any late effects of treatment and to watch for signs or symptoms of the tumor returning. Imaging scans and other tests will be done. […] […] Your child may need therapy to help with movement and muscle strength. This may be done by physical and occupational therapists. […] […] You can help your child manage treatment in many ways. For instance: […] […] Get emotional support for your child. Find a counselor, psychologist, or child support group that can help. […] […] Make sure your child attends all follow-up appointments. […] […] Talk with your child’s healthcare provider about side effects linked with their treatment. Tell them about any changes you notice. There are often ways to manage side effects. There may be things your child can do and medicines they can take to help prevent or control many treatment side effects. […] […] Most side effects get better and go away over time after treatment ends. But some can last the rest of your child’s life. Talk to your child’s treatment team about what you can expect. […] […] Continuous follow-up care during and after treatment is needed.

• #63 Research-Driven Efforts Push Neuroblastoma Care Forward – UCSF Pediatrics

  https://medconnection.ucsfbenioffchildrens.org/news/research-driven-efforts-push-neuroblastoma-care-forward

  There are currently few curative therapies for neuroblastoma. […] Ongoing research efforts at UCSF Benioff Childrens Hospitals aim to change that. […] Thanks to the persistence and expertise of Dr. Matthay and other pioneers in the field of neuroblastoma biology and clinical trial development, targeted agents and biomarkers have advanced the field of neuroblastoma care. […] We have a robust, extensive portfolio of neuroblastoma clinical trials that attracts many patients seeking access to new, targeted molecular therapies and immunotherapies otherwise unavailable outside of a clinical trial for neuroblastoma. […] Our program is providing critical access to new anticancer drugs for children and young adults with advanced neuroblastoma who desperately need new therapies. […] Dr. Vos statement encapsulates the end goal of most research on neuroblastoma care: seeking to improve upfront therapy and finding more effective treatments when disease returns. […] We always strive for more effective, less toxic therapy with limited long-term side effects. […] Weve made numerous improvements in survival in an upfront setting against advanced neuroblastoma, but these are questions we are still working on and will continue to do so in the future.

• #64 Research-Driven Efforts Push Neuroblastoma Care Forward – UCSF Pediatrics

  https://medconnection.ucsfbenioffchildrens.org/news/research-driven-efforts-push-neuroblastoma-care-forward

  There are currently few curative therapies for neuroblastoma. […] Ongoing research efforts at UCSF Benioff Childrens Hospitals aim to change that. […] Thanks to the persistence and expertise of Dr. Matthay and other pioneers in the field of neuroblastoma biology and clinical trial development, targeted agents and biomarkers have advanced the field of neuroblastoma care. […] We have a robust, extensive portfolio of neuroblastoma clinical trials that attracts many patients seeking access to new, targeted molecular therapies and immunotherapies otherwise unavailable outside of a clinical trial for neuroblastoma. […] Our program is providing critical access to new anticancer drugs for children and young adults with advanced neuroblastoma who desperately need new therapies. […] Dr. Vos statement encapsulates the end goal of most research on neuroblastoma care: seeking to improve upfront therapy and finding more effective treatments when disease returns. […] We always strive for more effective, less toxic therapy with limited long-term side effects. […] Weve made numerous improvements in survival in an upfront setting against advanced neuroblastoma, but these are questions we are still working on and will continue to do so in the future.

• #65 Research-Driven Efforts Push Neuroblastoma Care Forward – UCSF Pediatrics

  https://medconnection.ucsfbenioffchildrens.org/news/research-driven-efforts-push-neuroblastoma-care-forward

  There are currently few curative therapies for neuroblastoma. […] Ongoing research efforts at UCSF Benioff Childrens Hospitals aim to change that. […] Thanks to the persistence and expertise of Dr. Matthay and other pioneers in the field of neuroblastoma biology and clinical trial development, targeted agents and biomarkers have advanced the field of neuroblastoma care. […] We have a robust, extensive portfolio of neuroblastoma clinical trials that attracts many patients seeking access to new, targeted molecular therapies and immunotherapies otherwise unavailable outside of a clinical trial for neuroblastoma. […] Our program is providing critical access to new anticancer drugs for children and young adults with advanced neuroblastoma who desperately need new therapies. […] Dr. Vos statement encapsulates the end goal of most research on neuroblastoma care: seeking to improve upfront therapy and finding more effective treatments when disease returns. […] We always strive for more effective, less toxic therapy with limited long-term side effects. […] Weve made numerous improvements in survival in an upfront setting against advanced neuroblastoma, but these are questions we are still working on and will continue to do so in the future.

• #66 Research-Driven Efforts Push Neuroblastoma Care Forward – UCSF Pediatrics

  https://medconnection.ucsfbenioffchildrens.org/news/research-driven-efforts-push-neuroblastoma-care-forward

  There are currently few curative therapies for neuroblastoma. […] Ongoing research efforts at UCSF Benioff Childrens Hospitals aim to change that. […] Thanks to the persistence and expertise of Dr. Matthay and other pioneers in the field of neuroblastoma biology and clinical trial development, targeted agents and biomarkers have advanced the field of neuroblastoma care. […] We have a robust, extensive portfolio of neuroblastoma clinical trials that attracts many patients seeking access to new, targeted molecular therapies and immunotherapies otherwise unavailable outside of a clinical trial for neuroblastoma. […] Our program is providing critical access to new anticancer drugs for children and young adults with advanced neuroblastoma who desperately need new therapies. […] Dr. Vos statement encapsulates the end goal of most research on neuroblastoma care: seeking to improve upfront therapy and finding more effective treatments when disease returns. […] We always strive for more effective, less toxic therapy with limited long-term side effects. […] Weve made numerous improvements in survival in an upfront setting against advanced neuroblastoma, but these are questions we are still working on and will continue to do so in the future.

• #67 Neuroblastoma Treatments | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/pediatrics/cancer-care/types/neuroblastoma/treatment

  Once we know the stage of your childs neuroblastoma, well speak with you about the best treatments. At MSK Kids, your child has access to every type of neuroblastoma treatment, including surgery, chemotherapy, radiation therapy, immunotherapies with antibodies, cancer vaccines, T-cells and NK-cells, and genetically-guided therapy. […] In addition to the information we learned during staging, we use a tool developed at MSK called MSK-IMPACT. This test allows us to analyze every neuroblastoma for genetic mutations so we can target the cancer using novel anticancer drugs. […] If your child must have surgery, MSKs neuroblastoma surgeons have excellent success in safely removing even the most challenging tumors. […] Many children with intermediate- to high-risk neuroblastoma receive a combination of chemotherapy drugs before or after surgery to shrink the tumor and destroy any cancer cells in the body.

• #68 The Role of Nursing Professionals in the Management of Patients With High-Risk Neuroblastoma Receiving Dinutuximab Therapy

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7523913/

  Neuroblastoma, an embryonic cancer of the sympathetic nervous system, is the most common extracranial solid tumor in childhood. […] However, the safe and effective use of dinutuximab therapy in these high-risk patients requires medical expertise in patient selection, treatment administration, and the monitoring and management of adverse events. […] Multi-institutional nursing approaches to implementing standard protocols ensure the effective management of high-risk neuroblastoma patients receiving dinutuximab immunotherapy. […] Understanding and implementing recommendations for the management of the clinically important and most common adverse events are essential to ensuring patient continuation of therapy and improving patient outcomes. […] Nurses, as key members of the multidisciplinary team managing patients with high-risk neuroblastoma, play a critical role in administering therapy, managing AEs, and educating patients and families.

• #69 The Role of Nursing Professionals in the Management of Patients With High-Risk Neuroblastoma Receiving Dinutuximab Therapy

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7523913/

  The expert assessment and management of AEs, as well as preparation of and collaboration with patients and families, will facilitate patients remaining on therapy and receiving the full cycle of treatment, thereby optimizing the possibility of long-term control. […] The critical and diverse roles of the nurse should not be underestimated and include responsibilities of patient education, pretreatment planning, monitoring during therapy, early AE identification, and safe treatment when AEs occur. […] As the use of dinutuximab in the treatment of high-risk neuroblastoma expands, astute assessment and management of treatment-related AEs will be fundamental to improving patient adherence to therapy and outcomes.

• #70 What is Neuroblastoma – Pediatric Hematology/Oncology – Golisano Children’s Hospital – University of Rochester Medical Center

  https://www.urmc.rochester.edu/childrens-hospital/hemonc/neuroblastoma

  You can help your child manage treatment in many ways. For instance: […] Your child may have trouble eating. A dietitian may be able to help. […] Your child may be very tired. They will need to balance rest and activity. Encourage your child to be active. This is good for overall health. And it may help to reduce tiredness. Ask your child’s healthcare provider what exercises are safe for your child. […] Get emotional support for your child. Find a counselor, psychologist, or child support group that can help. […] Make sure your child attends all follow-up appointments. […] Talk with your child’s healthcare provider about side effects linked with their treatment. Tell them about any changes you notice. There are often ways to manage side effects. There may be things your child can do and medicines they can take to help prevent or control many treatment side effects. […] Most side effects get better and go away over time after treatment ends. But some can last the rest of your child’s life. Talk to your child’s treatment team about what you can expect. […] Continuous follow-up care during and after treatment is needed.

• #71 Neuroblastoma Program | Children’s Hospital Los Angeles

  https://www.chla.org/cancer-and-blood-disease-institute/programs-and-services/neuroblastoma-program

  Your child receives care from pediatric oncologists specializing in neuroblastoma and a program thats been a world leader for decades. […] Nurses help coordinate care and answer questions between appointments. Social workers help you address challenges related to your childs care and provide emotional support. […] We are grateful for and responsive to the input of our patients families. These family members guide education and support efforts that make living with a childs neuroblastoma diagnosis a little easier. […] Your child receives care from doctors with expertise in pediatric surgical oncology and neuroblastoma. These doctors specialize in safely removing neuroblastoma tumors that are difficult to remove. […] Our team is uncovering promising new care methods for neuroblastoma, including more options for high-risk neuroblastoma.

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