Materiały źródłowe

• #1 Sarcoma | Nebraska Hematology Oncology – Cancer Care Treatment Blood Disorders Clinical Trials Lincoln Nebraska (NE)

  https://www.yourcancercare.com/types-of-cancer/sarcoma

  Sarcomas are a varied group of cancers arising from fibrous tissue, adipose tissue (fat cells), skeletal muscle, smooth muscle, blood vessels, lymph vessels, nervous tissue, mesenchymal cells, bone, and cartilage. […] Sarcomas comprise 3% of all cancers in adults and 7% of cancers in children. […] Because of the rarity of each type of sarcoma, it may be important for patients to be treated in specialty centers with access to clinical research studies. […] Soft Tissue Sarcoma Screening and Prevention.

• #1 Sarcoma: Symptoms, types, treatments, and causes

  https://www.medicalnewstoday.com/articles/301762

  Unlike other types of cancer, lifestyle factors do not seem to play a role in the onset of sarcoma. […] Although adopting a healthful lifestyle is a good idea for reducing the risk of many conditions, there does not seem to be a specific link with sarcoma. […] It is not usually possible to prevent sarcoma, as doctors do not yet know what causes it.

• #1

  https://winshipcancer.emory.edu/cancer-types-and-treatments/sarcoma/prevention.php

  Prevention is not yet possible for sarcomas, but Winships team of experts continues to work on sarcoma prevention to give you the best outcomes possible. […] The vast majority of sarcomas are sporadic, meaning they occur at random with no known way to prevent them. […] While sarcomas cannot be prevented, there are ways to effectively diagnose and treat them. […] Sarcoma prevention does not yet exist. According to experts, there are no lifestyle-related or environmental causes of sarcoma, which means that there is no determined way to prevent these tumors from forming.

• #1 Soft Tissue Sarcoma | Hematology-Oncology Associates of CNY

  https://www.hoacny.com/our-services/cancers-we-treat/soft-tissue-sarcoma

  Having certain inherited disorders can increase the risk of soft tissue sarcoma. […] Risk factors for soft tissue sarcoma include the following inherited disorders: Li-Fraumeni syndrome (TP53 mutation), von Recklinghausen disease (neurofibromatosis type 1; NF1 mutation), Gardner syndrome (APC mutation), Nevoid basal cell carcinoma syndrome (Gorlin syndrome; PTCH1 mutation), Tuberous sclerosis (Bourneville disease; TSC1 or TSC2 mutation), Werner syndrome (adult progeria; WRN mutation). […] Other risk factors for soft tissue sarcoma include the following: Past treatment with radiation therapy, having lymphedema in the arms or legs for a long time, being exposed to certain chemicals, such as Thorotrast (thorium dioxide), vinyl chloride, or arsenic, being infected with HIV and human herpesvirus 8.

• #1 Sarcoma Awareness Month | AACR

  https://www.aacr.org/patients-caregivers/awareness-months/sarcoma-and-bone-cancer-awareness-month/

  Having certain inherited disorders can increase the risk for soft tissue sarcomas. These include retinoblastoma, tuberous sclerosis, Werner syndrome, and nevoid basal cell carcinoma syndrome. […] Other risk factors for soft tissue sarcomas include past treatment with radiation therapy for certain cancers; exposure to certain chemicals, such as thorium dioxide, vinyl chloride, or arsenic; and long-term lymphedema in the arms or legs. […] Past treatment with radiation can increase the risk of osteosarcoma and other types of bone cancers. Other risk factors for osteosarcoma include treatment with anticancer drugs called alkylating agents. Having a certain change in the retinoblastoma gene is also a risk factor. So is having certain conditions including Paget disease, Diamond-Blackfan anemia, and Werner syndrome.

• #1 Sarcoma Awareness and Prevention | Sarcoma | UT Southwestern Medical Center

  https://devtest.utswmed.org/conditions-treatments/sarcoma/sarcoma-awareness-and-prevention/

  Its important for people to know the symptoms and risk factors for sarcoma, especially those with a family history of the disease. […] Risk factors for soft-tissue and bone sarcomas include: […] Exposure to radiation […] Certain family cancer syndromes […] Exposure to certain chemicals […] Pagets disease.

• #1 Soft Tissue Sarcoma Risk Factors and Prevention Measures

  https://www.hcgoncology.com/types-of-cancers/soft-tissue-sarcoma-prevention/

  Several factors enhance the risk of soft tissue sarcoma. Clinicians must identify those risk factors and provide appropriate preventive measures to lower the risk of developing soft tissue sarcoma. […] Although it is impossible to prevent soft tissue sarcoma, certain soft tissue sarcoma prevention measures lower its risk. Soft tissue sarcoma prevention strategies include minimizing modifiable risk factors and adhering to a healthy lifestyle. Some soft tissue sarcoma prevention measures are: […] Minimizing exposure to ionizing radiation from medical treatments or occupational sources may lower the risk of radiation-induced soft tissue sarcomas. […] Reducing exposure to harmful chemicals in the workplace or the environment, following safety guidelines, and using protective measures while working with harmful chemicals can reduce the risk of soft tissue sarcoma.

• #1 Uterine Sarcoma: Symptoms, Diagnosis, Treatment & Prevention

  https://my.clevelandclinic.org/health/diseases/16408-uterine-sarcoma

  We don’t know how to prevent uterine sarcoma yet, but we know about certain risk factors, such as receiving pelvic area radiation and taking tamoxifen for breast cancer. Treatment benefits often outweigh the risks associated with developing uterine sarcoma, especially since it’s so rare. […] Speak to your provider about the risks associated with any cancer treatment, and weigh the pros and cons of the treatment options available.

• #1 Soft Tissue Sarcoma Risk Factors and Prevention Measures

  https://www.hcgoncology.com/types-of-cancers/soft-tissue-sarcoma-prevention/

  Individuals with a family history of soft tissue sarcoma or those who are suffering from genetic syndromes that enhance the risk of soft tissue sarcoma should be provided genetic counseling. Information should be obtained about their risk of developing soft tissue sarcoma. […] Like other cancers, a healthy lifestyle reduces the risk of soft tissue sarcoma. It helps improve the immune system and enhances the body’s ability to fight against abnormal cells. Engaging in regular physical activity may prevent cancer. A well-balanced diet comprising vegetables, fruits, and whole grains supports a healthy immune system. […] Excessive exposure to solar radiation should be avoided to lower the risk of soft tissue sarcoma. It includes going out in the sun only when necessary and using sunscreen lotions.

• #1

  https://www.healthxchange.sg/cancer/coping-tips/heart-cancer-cardiac-sarcoma-how-to-prevent-manage

  As mentioned, heart cancer (cardiac sarcoma) is extremely rare. Adopting healthy behaviours help to lower risk of both cancer and heart disease. These include: […] Avoid the use of tobacco – If you are a smoker, quit. […] Adopt a healthy diet rich in fruits, vegetables and whole grains, and low in unhealthy fats. Reduce consumption of red or processed meat, and drink alcohol in moderation. […] Maintain a healthy weight and be physically active. […] Go for regular tests for cancers and heart disease.

• #1 Sarcoma awareness: Understanding causes, prevention, and treatment

  https://www.medmalnj.com/sarcoma-awareness-understanding-causes-prevention-and-treatment/

  July is Sarcoma Awareness Month, a time to focus on learning more about this potentially deadly group of cancers. […] How can I reduce the risk of developing sarcoma? […] Certain chemicals and toxins may contribute to sarcoma, so it is wise to minimize exposure to these substances when possible. […] Regular check-ups and self-examinations are also important. Any unexplained lumps, pain, or swelling should prompt further investigation. It is important for patients to be proactive in seeking medical attention for suspicious symptoms.

• #1 Soft Tissue Sarcoma Screening and Prevention

  https://www.texasoncology.com/types-of-cancer/sarcoma/ewings-sarcoma/soft-tissue-sarcoma-screening-and-prevention

  Risk factors for soft tissue sarcoma are still poorly understood, and there are no known preventive strategies. […] There are no current screening techniques or effective preventative measures for soft tissue sarcoma. However, more than 70 percent of soft tissue sarcomas occur in areas of the extremities, trunk, and head and neck that are palpable (can be felt with the hands). Patients and parents should be aware of such painless growths and discuss them with their physician as soon as they are noticed.

• #1 Sarcoma Detection and Screening | Sarcoma Information | University of Michigan Rogel Cancer Center

  https://www.rogelcancercenter.org/sarcoma/screening-and-prevention

  People with a strong family history of sarcomas or other cancers occurring at a young age may wish to discuss the benefits and disadvantages of genetic testing with their doctor. […] Families with a history of certain inherited conditions caused by mutated tumor suppressor genes have an increased risk of developing soft tissue sarcomas. […] The only way to prevent some sarcomas is to avoid exposure to risk factors whenever this is possible. However, most sarcomas develop in people with no known risk factors, so there is no way known at this time to prevent most cases.

• #1 Soft Tissue Sarcoma Prevention | Stanford Health Care

  https://stanfordhealthcare.org/medical-conditions/cancer/soft-tissue-sarcoma/prevention.html

  Because most people who get soft tissue sarcoma do not have any risk factors, doctors have little advice on how you can prevent this very rare form of cancer. […] Remember, you can have all the risk factors and not get soft tissue sarcoma. Or you can have none of them and get this illness. Talk to your doctor if you are concerned about your risk. […] When possible, you should avoid these risk factors. […] Avoid exposure to radiation. (This may not be possible for people who need radiation to treat cancer.) […] Avoid exposure to certain chemicals, especially herbicides and dioxin. […] If you or anyone in your family has had neurofibromatosis, Li-Fraumeni syndrome, retinoblastoma, or soft tissue sarcoma, you may have a slightly elevated risk of this type of cancer. Ask your doctor if you should be tested for inherited genes that might increase your risk of soft tissue sarcoma. It is important to know that there are not a lot of genetic tests to accurately predict your risk for sarcomas.

• #1 Kaposi Sarcoma Treatment & Prevention | FL Dermatologists

  https://www.wederm.com/patient-library/kaposi-sarcoma/

  Kaposi Sarcoma Preventions […] There is no vaccine for HHV-8. Since most KS cases in the U.S. develop in people with HIV and AIDS, the best way to reduce your risk of KS is to avoid becoming infected with HIV. You can do this by: […] Getting tested for HIV and encouraging your partner to do so before having sex […] Using condoms when you have sex, especially vaginal and anal sex […] Limiting your number of sex partners […] Taking pre-exposure prophylaxis (PrEP) drugs if you’re at high risk of contracting HIV […] Refraining from injecting drugs or from sharing needles if you do inject drugs.

• #1 Kaposi’s Sarcoma – Types | Signs | Symptoms | Diagnosis | Treatment | Prevention

  https://www.icliniq.com/articles/cancer/kaposis-sarcoma

  No vaccine can protect you against HHV-8. So the best way to prevent KS is by avoiding things that increase the risk of HIV, such as unprotected sex and using injectable drugs. […] AIDS or HIV patients can reduce the risk of KS by taking antiretroviral drugs. […] Organ transplant patients can reduce the risk of KS by using some anti-rejection drugs.

• #1 Cancer prevention and control: Kaposi’s sarcoma – ecancer

  https://ecancer.org/en/journal/article/951-cancer-prevention-and-control-kaposis-sarcoma

  At a population level, a key preventive strategy would be breaking the transmission of KSHV through exchange of saliva. […] Even though there is no cure at present, the expanding knowledge of KS biology increases hope for prevention and control of the disease hence better quality of life among patients with KS. Primary prevention strategy for KSHV and management of disease complication such as lymphedema should be the focus of research.

• #1 GUIDELINE for Feline Injection-Site Sarcoma — ABCD cats & vets

  https://www.abcdcatsvets.org/guideline-for-feline-injection-site-sarcoma/

  In cats, invasive sarcomas (mostly fibrosarcomas), so called feline injection-site sarcomas (FISS), are the most serious adverse effects following vaccination. These tumours develop at sites of vaccination or of injection of other substances. They have characteristics that are distinct from those of fibrosarcomas in other areas and behave more aggressively. The rate of metastasis ranges from 10% to 28%. […] To prevent FISS development, several recommendations should be followed: Although vaccinations can be associated with FISS formation, immunisation of cats with various vaccines provides essential protection and should not be stopped because of the risk of FISS. It is important to realize that vaccines are not the only injectable medical products associated with FISS. […] Generally, any skin or subcutaneous mass in a cat requires further diagnostics. Specifically, thorough post-vaccination monitoring should be performed considering the 3-2-1-rule: Any lump at the site of injection that is still present three months after vaccination, or that is larger than 2cm in diameter, or that is increasing in size one month after vaccination should be surgically removed and investigated through histopathology.

• #1 GUIDELINE for Feline Injection-Site Sarcoma — ABCD cats & vets

  https://www.abcdcatsvets.org/guideline-for-feline-injection-site-sarcoma/

  ABCD recommends that veterinarians carry out a risk-benefit analysis for each vaccine to avoid unnecessary vaccination of cats, to monitor the injection site, and to report all vaccine-associated adverse events to the manufacturer and/or to their competent authority. […] Prevention consists of three general considerations. First, injections in cats should always be given at sites at which surgery (such as amputation of a limb or excision of lateral abdominal skin) would likely lead to a complete cure with the least complicated surgical procedure. Second, general recommendations to reduce the inflammatory reaction at injection sites should be followed, such as avoiding the administration of irritating substances. And third, it is advised to vaccinate as often as necessary, but as infrequently as possible.

• #1 Mecapegfilgrastim for prophylaxis of febrile neutropenia in children and adolescents with rhabdomyosarcoma or Ewing sarcoma: a prospective, single-arm, pilot study | BMC Cancer | Full Text

  https://bmccancer.biomedcentral.com/articles/10.1186/s12885-024-12766-w

  The chemotherapy regimens recommended for both rhabdomyosarcoma (RMS) and Ewing sarcoma (ES) patients are myelosuppressive and can reduce the absolute neutrophil count (ANC) and subsequently increase the risk of febrile neutropenia (FN). […] Our objective was to investigate the efficacy and safety of mecapegfilgrastim, a biosimilar of pegfilgrastim, in prophylaxis of FN for pediatric and adolescent patients with RMS or ES. […] Currently, granulocyte-colony stimulating factor (G-CSF) drugs have been recognized as one of the most commonly used regimens for prophylaxis of chemotherapy-induced FN and neutropenia, however, only a few studies have focused on the efficacy and safety of G-CSF drugs in pediatric and adolescent patients. […] Mecapegfilgrastim, a PEG-rhG-CSF, is a biosimilar of pegfilgrastim that has shown promising clinical benefit in the prevention of chemotherapy-induced FN and neutropenia in many solid tumors, such as lung cancer.

• #1 Mecapegfilgrastim for prophylaxis of febrile neutropenia in children and adolescents with rhabdomyosarcoma or Ewing sarcoma: a prospective, single-arm, pilot study | BMC Cancer | Full Text

  https://bmccancer.biomedcentral.com/articles/10.1186/s12885-024-12766-w

  On the basis of the above information, we conducted this pilot, single-arm study aimed to explore the efficacy and safety of mecapegfilgrastim for the prophylaxis of FN in pediatric and adolescent patients with RMS or ES. […] The primary endpoint was the incidence rate of FN defined as a temperature of38.3 or two consecutive readings of38.0 for 2 h and an absolute neutrophil count (ANC) of0.5109/L, or expected to fall below 0.5109/L. […] Overall, 2 of the 30 (6.7%, 95% CI: 0.8222.07) patients experienced FN after the first cycle of chemotherapy. […] Mecapegfilgrastim showed acceptable efficacy and safety profile in pediatric and adolescent patients with RMS or ES. […] Patients who are treated with the VDC regimen should be monitored with caution even after receiving long-acting rhG-CSF drugs.

• #1 Protected environment – prophylactic antibiotic program for malignant sarcomas: randomized trial during remission induction chemotherapy – PubMed

  https://pubmed.ncbi.nlm.nih.gov/7272896/

  Fifty-one valuable patients with malignant sarcomas were randomly allocated to receive three courses of remission induction chemotherapy with cyclophosphamide, vincristine, Adriamycin, and dimethyl triazeno imidazole carboxamide (CYVADIC) on the protected environment-prophylactic antibiotic for the control group (P = 0.22). […] The frequency of infection was significantly lower among the PEPA patients, and the doses of CYVADIC could be escalated more often among these patients. […] Dosage escalation was associated with a higher complete remission rate and lower fatality rate. […] Sarcoma / prevention control

• #1 Antibiotic prophylaxis for prevention of wound infections after soft tissue sarcoma resection: A retrospective cohort study – PubMed

  https://pubmed.ncbi.nlm.nih.gov/32851680/

  Background and objectives: The use of antibiotic prophylaxis for soft tissue sarcoma resection varies widely while little evidence on this topic exists. The aim of this study was to determine the impact of antibiotic prophylaxis on the occurrence of wound infections. […] Antibiotic prophylaxis could not be identified as a protective factor in univariate or multivariate analysis. […] A favorable effect of antibiotic prophylaxis on the occurrence of wound infections could not be observed. Although more studies on this subject are needed, our data do not support the general use of antibiotic prophylaxis for soft tissue sarcoma resection.

• #1 Soft Tissue Sarcoma Screening and Prevention | Nebraska Hematology Oncology – Cancer Care Treatment Blood Disorders Clinical Trials Lincoln Nebraska (NE)

  https://www.yourcancercare.com/types-of-cancer/sarcoma/ewings-sarcoma/soft-tissue-sarcoma-screening-and-prevention

  Information about the prevention of cancer and the science of screening appropriate individuals at high risk of developing cancer is gaining interest. […] Risk factors for soft tissue sarcoma are still poorly understood, and there are no known preventive strategies. […] There are no current screening techniques or effective preventative measures for soft tissue sarcoma.

• #1 Soft Tissue Sarcoma Prevention | Stanford Health Care

  https://stanfordhealthcare.org/medical-conditions/cancer/soft-tissue-sarcoma/prevention.html

  Unfortunately, there is no test that can find sarcoma cells when they first begin to grow. However, you have a better chance of surviving soft tissue sarcoma if it is found and treated early. For this reason, it is important to tell your doctor right away if you notice any lumps or other symptoms on your body. If you feel a lump on your body, it is important to have your doctor check it. This is especially true if the lump is causing pain or is getting larger. Even though most lumps are not sarcomas, you can’t assume so. Your doctor may continue to watch the lump or have tests done. […] Don’t be afraid to question your doctor and ask for more tests to make yourself feel better. It is your health and your body and it is important to know confidently that any concern you have has been completely evaluated to your satisfaction.

• #1 Yellow July raises awareness for Sarcoma: understand the disease | Oncoclínicas Group Yellow July raises awareness for Sarcoma: understand the disease | Oncoclínicas Group

  https://grupooncoclinicas.com/en/blog/yellow-july-raises-awareness-for-sarcoma-understand-the-disease/

  Is prevention possible? […] The vast majority of sarcomas are not linked to a specific cause, making it impossible to define a way to prevent the tumor. […] However, Bruna David emphasizes the importance of being attentive to the signs. […] It is important to remember that, as they are rare and composed of many subtypes within rarity, they should be seen and treated by professionals trained in this type of disease. […] It has been proven that this also impacts the prognosis. […] And of course, the earlier the diagnosis, the greater the chance of success in treatment, she concludes.

• #1 Soft Tissue Sarcoma Risk Factors and Prevention Measures

  https://www.hcgoncology.com/types-of-cancers/soft-tissue-sarcoma-prevention/

  It is important to consult the oncologists immediately if any symptom may cause concern, especially in people with a high risk for soft tissue sarcoma or individuals with a history of soft tissue sarcoma. Early detection helps with appropriate intervention and improves overall outcomes. […] Soft tissue sarcoma prevention may be achieved through minimizing radiation exposure, safeguarding against chemical exposure, and maintaining a healthy lifestyle. […] Soft tissue sarcoma prevention measures include reduced radiation and chemical exposure, a healthy lifestyle, and routine monitoring.

• #2 Sarcoma Information & Care | Banner MD Anderson

  https://www.bannerhealth.com/services/cancer/cancer-type/sarcoma

  Sarcoma Risk Factors Prevention […] Sarcoma Treatment and Support […] Sarcoma Tests and Diagnosis […] Sarcoma Symptoms […] Sarcoma Types […] Sarcoma is a type of cancer that starts in the tissues of the body. While there are about 70 different types of sarcomas, they are characterized by two main types bone and soft tissue sarcoma. […] Although sarcoma is a rare form of cancer, both children and adults can develop the disease. […] While the exact causes of sarcomas are unknown, family history, Pagets disease, certain genetic disorders or exposure to radiations or chemicals can increase your risk of developing sarcoma. […] Soft tissue sarcomas can be difficult to spot as they can grow in any part of the body. […] Sarcomas found in the back of the abdomen (retroperitoneum) produce symptoms that develop from problems the tumor is causing (blockage or bleeding of the stomach or bowels, pressing on nerves or blood vessels or nearby organs).

• #2 Soft Tissue Sarcoma Causes, Risk Factors, and Prevention | American Cancer Society

  https://www.cancer.org/cancer/types/soft-tissue-sarcoma/causes-risks-prevention.html

  The only way to prevent some soft tissue sarcomas is to avoid exposure to risk factors whenever possible. […] At this time, there’s no known way to prevent this cancer.

• #2 Sarcoma Risk Factors & Prevention | Banner MD Anderson

  https://www.bannerhealth.com/services/cancer/cancer-type/sarcoma/risk-factors-and-prevention

  Currently, there is no known way to prevent sarcoma. Avoiding exposure to risk factors whenever possible is an option, but most sarcomas develop in people with no known risk factors. […] Not everyone with these risk factors develop sarcoma. If you have any risk factors, discuss them with your doctor at Banner MD Anderson.

• #2 Sarcoma Awareness Month | AACR

  https://www.aacr.org/patients-caregivers/awareness-months/sarcoma-and-bone-cancer-awareness-month/

  Having certain inherited disorders can increase the risk for soft tissue sarcomas. These include retinoblastoma, tuberous sclerosis, Werner syndrome, and nevoid basal cell carcinoma syndrome. […] Other risk factors for soft tissue sarcomas include past treatment with radiation therapy for certain cancers; exposure to certain chemicals, such as thorium dioxide, vinyl chloride, or arsenic; and long-term lymphedema in the arms or legs. […] Past treatment with radiation can increase the risk of osteosarcoma and other types of bone cancers. Other risk factors for osteosarcoma include treatment with anticancer drugs called alkylating agents. Having a certain change in the retinoblastoma gene is also a risk factor. So is having certain conditions including Paget disease, Diamond-Blackfan anemia, and Werner syndrome.

• #2 Soft Tissue Sarcoma | Hematology-Oncology Associates of CNY

  https://www.hoacny.com/our-services/cancers-we-treat/soft-tissue-sarcoma

  Having certain inherited disorders can increase the risk of soft tissue sarcoma. […] Risk factors for soft tissue sarcoma include the following inherited disorders: Li-Fraumeni syndrome (TP53 mutation), von Recklinghausen disease (neurofibromatosis type 1; NF1 mutation), Gardner syndrome (APC mutation), Nevoid basal cell carcinoma syndrome (Gorlin syndrome; PTCH1 mutation), Tuberous sclerosis (Bourneville disease; TSC1 or TSC2 mutation), Werner syndrome (adult progeria; WRN mutation). […] Other risk factors for soft tissue sarcoma include the following: Past treatment with radiation therapy, having lymphedema in the arms or legs for a long time, being exposed to certain chemicals, such as Thorotrast (thorium dioxide), vinyl chloride, or arsenic, being infected with HIV and human herpesvirus 8.

• #2 Can Soft Tissue Sarcomas Be Prevented? | American Cancer Society

  https://www.cancer.org/cancer/types/soft-tissue-sarcoma/causes-risks-prevention/prevention.html

  The only way to prevent some soft tissue sarcomas is to avoid exposure to risk factors whenever possible. But most sarcomas develop in people with no known risk factors, so, at this time, there’s no known way to prevent most cases. […] And for people getting radiation therapy, there’s usually little choice.

• #2 Reducing your risk for soft tissue sarcoma | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/soft-tissue-sarcoma/risks/reducing-your-risk

  You may lower your risk of developing soft tissue sarcoma by doing the following. […] Coming into contact with vinyl chloride or thorium dioxide increases your risk for some types of soft tissue sarcoma. Having contact with dioxin may also put you at risk. Following health and safety guidelines can help you lower your contact with these chemicals.

• #2 Soft Tissue Sarcoma Risk Factors and Prevention Measures

  https://www.hcgoncology.com/types-of-cancers/soft-tissue-sarcoma-prevention/

  Individuals with a family history of soft tissue sarcoma or those who are suffering from genetic syndromes that enhance the risk of soft tissue sarcoma should be provided genetic counseling. Information should be obtained about their risk of developing soft tissue sarcoma. […] Like other cancers, a healthy lifestyle reduces the risk of soft tissue sarcoma. It helps improve the immune system and enhances the body’s ability to fight against abnormal cells. Engaging in regular physical activity may prevent cancer. A well-balanced diet comprising vegetables, fruits, and whole grains supports a healthy immune system. […] Excessive exposure to solar radiation should be avoided to lower the risk of soft tissue sarcoma. It includes going out in the sun only when necessary and using sunscreen lotions.

• #2 Soft Tissue Sarcoma Prevention | Stanford Health Care

  https://stanfordhealthcare.org/medical-conditions/cancer/soft-tissue-sarcoma/prevention.html

  Unfortunately, there is no test that can find sarcoma cells when they first begin to grow. However, you have a better chance of surviving soft tissue sarcoma if it is found and treated early. For this reason, it is important to tell your doctor right away if you notice any lumps or other symptoms on your body. If you feel a lump on your body, it is important to have your doctor check it. This is especially true if the lump is causing pain or is getting larger. Even though most lumps are not sarcomas, you can’t assume so. Your doctor may continue to watch the lump or have tests done. […] Don’t be afraid to question your doctor and ask for more tests to make yourself feel better. It is your health and your body and it is important to know confidently that any concern you have has been completely evaluated to your satisfaction.

• #2 Explore Ewing Sarcoma Prevention Risk factors and Prevention Measures at HCG Oncology

  https://www.hcgoncology.com/types-of-cancers/ewing-sarcoma-prevention/

  A regular medical checkup is another way to detect and treat cancer in its early stages. The patients should not ignore any of the symptoms of Ewing sarcoma, such as bone pain, unexplained weight loss, or persistent fatigue. […] The preventive measures for Ewing sarcoma include regular medical checkups, quitting smoking, and maintaining a healthy weight.

• #2 Soft Tissue Sarcoma Prevention | Stanford Health Care

  https://stanfordhealthcare.org/medical-conditions/cancer/soft-tissue-sarcoma/prevention.html

  Because most people who get soft tissue sarcoma do not have any risk factors, doctors have little advice on how you can prevent this very rare form of cancer. […] Remember, you can have all the risk factors and not get soft tissue sarcoma. Or you can have none of them and get this illness. Talk to your doctor if you are concerned about your risk. […] When possible, you should avoid these risk factors. […] Avoid exposure to radiation. (This may not be possible for people who need radiation to treat cancer.) […] Avoid exposure to certain chemicals, especially herbicides and dioxin. […] If you or anyone in your family has had neurofibromatosis, Li-Fraumeni syndrome, retinoblastoma, or soft tissue sarcoma, you may have a slightly elevated risk of this type of cancer. Ask your doctor if you should be tested for inherited genes that might increase your risk of soft tissue sarcoma. It is important to know that there are not a lot of genetic tests to accurately predict your risk for sarcomas.

• #2 Kaposi’s Sarcoma (KS): Types, Causes, Symptoms, Treatment

  https://www.webmd.com/hiv-aids/aids-hiv-opportunistic-infections-kaposis-sarcoma

  Theres no vaccine to protect against HHV-8. The best way to avoid getting KS is to avoid things that put you at higher risk of HIV, such as having unprotected sex or injecting drugs with used needles. Medications called pre-exposure prophylaxis (PrEP) can also make you less likely to get HIV. […] If you have HIV, preventing KS should be possible with ART, especially if you start it when your CD4 count is still high. If you have advanced HIV, or AIDS, a test can tell if you also have HHV-8. ART will lower the chances that it will become KS. […] If youve had an organ transplant, some anti-rejection drugs can also lower your chance of getting KS.

• #2 Cancer prevention and control: Kaposi’s sarcoma – ecancer

  https://ecancer.org/en/journal/article/951-cancer-prevention-and-control-kaposis-sarcoma

  Kaposis sarcoma (KS) is a vascular tumour of endothelial origin that is associated with human herpes virus-8 infection. […] Expanding knowledge of KS biology increases hope for prevention, disease control, and hence better quality of life among patients. Primary prevention strategy for KS-associated herpes virus and management of disease complication, such as lymphoedema should be the focus of disease-prevention and -control research. […] Currently, there is no vaccine against KSHV and no primary prevention. Given the lack of knowledge of the route of acquisition, no proper prevention message can be provided to the public. Riding on the back of the HIV prevention success, the measures in place for HIV can be used in the prevention of a KS epidemic. […] From the clinical perspective, since the majority of tumour cells are latently infected with KSHV, lytic replication plays a major role in disease progression and virus dissemination. Therefore, transformation to lytic cycle could be a preventive strategy by increasing targets through augmented cell replication.

• #2 GUIDELINE for Feline Injection-Site Sarcoma — ABCD cats & vets

  https://www.abcdcatsvets.org/guideline-for-feline-injection-site-sarcoma/

  In general, injecting distally in the limb aids in the treatment of subsequent FISS (by amputation of the leg) because these tumours are very difficult to excise completely and often recur after resection. […] Unfortunately, there is still a lack of information to provide evidence-based vaccine site recommendations. […] Thus, owner education by the veterinarian explaining optimum treatment options is important. […] In addition to considering appropriate injection sites, post vaccination monitoring plays an important role. Vaccination sites should be noted in clinical records, and veterinarians should instruct their clients to monitor vaccination (or injection) sites for swelling or lumps so that potential FISS can be detected early, and thus can be removed successfully. […] Concerning general recommendations to prevent inflammatory reactions at injection sites, there are a few rules to follow. Generally, cats should receive as few subcutaneous injections as possible. Intramuscular injections in cats should be avoided because intramuscular tumours develop with a similar frequency but are more difficult to detect early. Whenever feasible, cats should receive drugs orally or intravenously. The subcutaneous injection of long-acting irritating substances (such as long-acting glucocorticoids) should be avoided.

• #2 Mecapegfilgrastim for prophylaxis of febrile neutropenia in children and adolescents with rhabdomyosarcoma or Ewing sarcoma: a prospective, single-arm, pilot study | BMC Cancer | Full Text

  https://bmccancer.biomedcentral.com/articles/10.1186/s12885-024-12766-w

  On the basis of the above information, we conducted this pilot, single-arm study aimed to explore the efficacy and safety of mecapegfilgrastim for the prophylaxis of FN in pediatric and adolescent patients with RMS or ES. […] The primary endpoint was the incidence rate of FN defined as a temperature of38.3 or two consecutive readings of38.0 for 2 h and an absolute neutrophil count (ANC) of0.5109/L, or expected to fall below 0.5109/L. […] Overall, 2 of the 30 (6.7%, 95% CI: 0.8222.07) patients experienced FN after the first cycle of chemotherapy. […] Mecapegfilgrastim showed acceptable efficacy and safety profile in pediatric and adolescent patients with RMS or ES. […] Patients who are treated with the VDC regimen should be monitored with caution even after receiving long-acting rhG-CSF drugs.

• #2 Soft Tissue Sarcoma Screening and Prevention

  https://www.texasoncology.com/types-of-cancer/sarcoma/ewings-sarcoma/soft-tissue-sarcoma-screening-and-prevention

  Risk factors for soft tissue sarcoma are still poorly understood, and there are no known preventive strategies. […] There are no current screening techniques or effective preventative measures for soft tissue sarcoma. However, more than 70 percent of soft tissue sarcomas occur in areas of the extremities, trunk, and head and neck that are palpable (can be felt with the hands). Patients and parents should be aware of such painless growths and discuss them with their physician as soon as they are noticed.

• #2 What is Sarcoma? | Sarah Cannon

  https://sarahcannon.com/for-patients/learn-about-cancer/sarcoma/index2.dot

  Sarcoma Prevention […] Because the cause of most forms of sarcoma is unknown, the only way to prevent some sarcomas is to avoid exposure to the risk factors above (though this isn’t always possible). Currently, there’s no proven way to prevent soft tissue sarcoma.

• #2 Kaposi’s Sarcoma – Types | Signs | Symptoms | Diagnosis | Treatment | Prevention

  https://www.icliniq.com/articles/cancer/kaposis-sarcoma

  No vaccine can protect you against HHV-8. So the best way to prevent KS is by avoiding things that increase the risk of HIV, such as unprotected sex and using injectable drugs. […] AIDS or HIV patients can reduce the risk of KS by taking antiretroviral drugs. […] Organ transplant patients can reduce the risk of KS by using some anti-rejection drugs.

• #2 Yellow July raises awareness for Sarcoma: understand the disease | Oncoclínicas Group Yellow July raises awareness for Sarcoma: understand the disease | Oncoclínicas Group

  https://grupooncoclinicas.com/en/blog/yellow-july-raises-awareness-for-sarcoma-understand-the-disease/

  Is prevention possible? […] The vast majority of sarcomas are not linked to a specific cause, making it impossible to define a way to prevent the tumor. […] However, Bruna David emphasizes the importance of being attentive to the signs. […] It is important to remember that, as they are rare and composed of many subtypes within rarity, they should be seen and treated by professionals trained in this type of disease. […] It has been proven that this also impacts the prognosis. […] And of course, the earlier the diagnosis, the greater the chance of success in treatment, she concludes.

• #3 GUIDELINE for Feline Injection-Site Sarcoma — ABCD cats & vets

  https://www.abcdcatsvets.org/guideline-for-feline-injection-site-sarcoma/

  Thus, vaccines should be taken out of the refrigerator and be brought to room temperature before injection, e.g., by keeping the vial in the palm of the hand for a short time but should be kept only briefly out of the refrigerator to avoid reduction in vaccinal efficacy. […] Regarding the risk of FISS development, intranasal vaccines are to be preferred over injectable vaccines in cats if similar efficacy has been demonstrated. However, in most countries, only injectable vaccines are available. Therefore, the vaccines that are preferred are those that cause the least subcutaneous inflammatory reaction. […] Finally, to prevent the development of FISS, cats should only be vaccinated as frequently as necessary, and long vaccination intervals should be applied in adult animals where possible.

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