Materiały źródłowe

• #1 Male Hypogonadism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK532933/

  Male hypogonadism, acquired or congenital, can be caused by defects that interfere with the hypothalamic-pituitary-testicular axis. Symptoms highly suggestive of hypogonadism include decreased spontaneous erections, decreased nocturnal penile tumescence, decreased libido, and reduced testicular volume. […] Symptoms highly suggestive of hypogonadism include decreased spontaneous erections, reduced nocturnal penile tumescence, infrequent morning erections, low libido, unexplained fatigue, and smaller testicular volume. […] Symptoms highly suggestive of androgen deficiency in men include reduced sexual desire, decreased spontaneous erections, fatigue, lethargy, loss of axillary and pubic hair, visual field changes (such as bitemporal hemianopsia), loss of smell (anosmia), declining or small testicular volume, hot flashes, and infertility with low or absent sperm counts. Other less suggestive symptoms include depressed mood, irritability, poor concentration, increased body fat, decreased physical performance, lower muscle mass, reduced endurance, weight loss, reduced energy, and loss of appetite.

• #2 Male hypogonadism: Symptoms, causes, and treatment

  https://www.medicalnewstoday.com/articles/307634

  Male hypogonadism, also known as testosterone deficiency, describes when the testes are unable to produce the male sex hormone testosterone, sperm, or both. […] The signs and symptoms depend on when it starts, how severe the deficiency is, and whether or not there is a decrease in the major functions of the testes. […] If hypogonadism occurs before puberty, puberty does not progress. If it occurs after puberty, there may be infertility and sexual dysfunction. […] In adult men, symptoms begin within a few weeks of the onset of testosterone deficiency. […] A lack of testosterone can cause a wide range of symptoms. […] Symptoms of adult-onset hypogonadism include: erectile dysfunction, low sperm count, depressed mood, decreased libido, lethargy, sleep disturbances, decreased muscle mass and strength, loss of body hair (pubic, axillary, facial), osteoporosis and decreased bone mineral density, increased body fat, breast discomfort and enlargement, hot flashes, sweating, poor concentration and decreased energy.

• #3 Male hypogonadism | UM Health-Sparrow

  https://www.uofmhealthsparrow.org/departments-conditions/conditions/male-hypogonadism

  Hypogonadism can begin during fetal development, before puberty or during adulthood. Signs and symptoms depend on when the condition develops. […] Male hypogonadism can delay puberty or cause incomplete or lack of normal development. It can hamper: […] In adult males, hypogonadism can alter certain masculine physical characteristics and impair normal reproductive function. Early signs and symptoms might include: […] Over time, men with hypogonadism can develop: […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include:

• #4 Male hypogonadism: Symptoms, causes, and treatment

  https://www.medicalnewstoday.com/articles/307634

  Male hypogonadism, also known as testosterone deficiency, describes when the testes are unable to produce the male sex hormone testosterone, sperm, or both. […] The signs and symptoms depend on when it starts, how severe the deficiency is, and whether or not there is a decrease in the major functions of the testes. […] If hypogonadism occurs before puberty, puberty does not progress. If it occurs after puberty, there may be infertility and sexual dysfunction. […] In adult men, symptoms begin within a few weeks of the onset of testosterone deficiency. […] A lack of testosterone can cause a wide range of symptoms. […] Symptoms of adult-onset hypogonadism include: erectile dysfunction, low sperm count, depressed mood, decreased libido, lethargy, sleep disturbances, decreased muscle mass and strength, loss of body hair (pubic, axillary, facial), osteoporosis and decreased bone mineral density, increased body fat, breast discomfort and enlargement, hot flashes, sweating, poor concentration and decreased energy.

• #5 Male hypogonadism: Symptoms and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3255409/

  Recent studies have found that testosterone production slowly decreases as a result of aging, although the rate of decline varies. […] The Baltimore Longitudinal Study of Aging reported that approximately 20% of men in their 60s and 50% of men in their 80s are hypogonadal. […] The proposed causes for the effects of obesity on testosterone level include increased clearance or aromatization of testosterone in the adipose tissue and increased formation of inflammatory cytokines, which hinder the secretion of the gonadotropin-releasing hormone. […] Hypogonadism affects men of all ages, either through congenital or acquired causes. For patients who have clinical symptoms associated with their low testosterone levels, treatment is essential for the prevention of sexual, cognitive, and bodily changes.

• #6 What Is Hypogonadism? Symptoms, Diagnosis, Treatment

  https://www.everydayhealth.com/sexual-health/hypogonadism/guide/

  Testosterone replacement may not only increase testosterone levels but also improve bone health, muscle development, and anemia (low red cells in the blood). […] An estimated 35 percent of men older than 45 and an estimated 30 to 50 percent of men with obesity or type 2 diabetes have hypogonadism, according to the Endocrine Society.

• #7 Male Hypogonadism – Genitourinary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/genitourinary-disorders/male-reproductive-endocrinology-and-related-disorders/male-hypogonadism

  Age at onset of testosterone deficiency (congenital, childhood-onset, or adult-onset hypogonadism) dictates the clinical presentation. […] Congenital hypogonadism may be of first-, second-, or third-trimester onset. Congenital hypogonadism of first-trimester onset results in inadequate male sexual differentiation. Complete absence of testosterone effects results in normal-appearing female external genitals. Partial testosterone deficiency results in abnormalities ranging from ambiguous external genitalia to hypospadias. Second- or third-trimester onset of testosterone deficiency results in microphallus and undescended testes. […] Childhood-onset testosterone deficiency is unrecognized until puberty is delayed. Untreated hypogonadism impairs development of secondary sexual characteristics. As adults, affected patients have poor muscle development, a high-pitched voice, a small scrotum, decreased phallic and testicular growth, sparse pubic and axillary hair, and an absence of body hair. They may develop gynecomastia and eunuchoidal body proportions because of delayed fusion of the epiphyses and continued long bone growth.

• #8 Testosterone Deficiency / Low (Hypogonadism): Causes, Symptoms, Diagnosis and Treatment

  https://dreminozbek.com/en/testosterone-deficiency-low-hypogonadism-causes-symptoms-diagnosis-and-treatment/

  Hypogonadism can begin during fetal development, before puberty or later in adulthood. Symptoms of testosterone deficiency vary according to the age at which the disease occurs. […] Symptoms of hypogonadism developing in the fetal period vary according to the degree of T deficiency. Although the child is genetically male, there is a problem in the genital organs; Insufficient development of male external genitalia, Feminine genitalia, Ambiguous genitalia (it is not clear whether the external genitalia is male or female). […] Puberty: Insufficient development of muscle mass, The lack of development of male voice character, Insufficient growth of hair, beard, genital area and body hair, Insufficient development of the penis and testicles, Longer extremities such as arms and legs compared to the trunk, Enlargement of the breasts (gynecomastia).

• #9 Male Hypogonadism – Genitourinary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/genitourinary-disorders/male-reproductive-endocrinology-and-related-disorders/male-hypogonadism

  Age at onset of testosterone deficiency (congenital, childhood-onset, or adult-onset hypogonadism) dictates the clinical presentation. […] Congenital hypogonadism may be of first-, second-, or third-trimester onset. Congenital hypogonadism of first-trimester onset results in inadequate male sexual differentiation. Complete absence of testosterone effects results in normal-appearing female external genitals. Partial testosterone deficiency results in abnormalities ranging from ambiguous external genitalia to hypospadias. Second- or third-trimester onset of testosterone deficiency results in microphallus and undescended testes. […] Childhood-onset testosterone deficiency is unrecognized until puberty is delayed. Untreated hypogonadism impairs development of secondary sexual characteristics. As adults, affected patients have poor muscle development, a high-pitched voice, a small scrotum, decreased phallic and testicular growth, sparse pubic and axillary hair, and an absence of body hair. They may develop gynecomastia and eunuchoidal body proportions because of delayed fusion of the epiphyses and continued long bone growth.

• #10 Male Hypogonadism – Genitourinary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/genitourinary-disorders/male-reproductive-endocrinology-and-related-disorders/male-hypogonadism

  Age at onset of testosterone deficiency (congenital, childhood-onset, or adult-onset hypogonadism) dictates the clinical presentation. […] Congenital hypogonadism may be of first-, second-, or third-trimester onset. Congenital hypogonadism of first-trimester onset results in inadequate male sexual differentiation. Complete absence of testosterone effects results in normal-appearing female external genitals. Partial testosterone deficiency results in abnormalities ranging from ambiguous external genitalia to hypospadias. Second- or third-trimester onset of testosterone deficiency results in microphallus and undescended testes. […] Childhood-onset testosterone deficiency is unrecognized until puberty is delayed. Untreated hypogonadism impairs development of secondary sexual characteristics. As adults, affected patients have poor muscle development, a high-pitched voice, a small scrotum, decreased phallic and testicular growth, sparse pubic and axillary hair, and an absence of body hair. They may develop gynecomastia and eunuchoidal body proportions because of delayed fusion of the epiphyses and continued long bone growth.

• #11 What is Male Hypogonadism? Signs, Symptoms, and Causes

  https://www.letsgetchecked.com/articles/male-hypogonadism-signs-symptoms-and-causes/?srsltid=AfmBOopswUWE-VT9lBXcDjIheH2Gt4tN4J2jSLCaLwjP9YpJkA-I6k4n

  Symptoms of hypogonadism at birth include: Ambiguous genitals, Underdeveloped male genitals, Female genitals. […] Symptoms of hypogonadism during puberty include: Development of breast tissue, Decreased development of muscle mass, Curbed deepening of the voice. […] Symptoms of hypogonadism during adulthood include: Decreased sex drive, Erectile dysfunction, Decrease in muscle mass.

• #12 Testosterone Deficiency / Low (Hypogonadism): Causes, Symptoms, Diagnosis and Treatment

  https://dreminozbek.com/en/testosterone-deficiency-low-hypogonadism-causes-symptoms-diagnosis-and-treatment/

  Hypogonadism can begin during fetal development, before puberty or later in adulthood. Symptoms of testosterone deficiency vary according to the age at which the disease occurs. […] Symptoms of hypogonadism developing in the fetal period vary according to the degree of T deficiency. Although the child is genetically male, there is a problem in the genital organs; Insufficient development of male external genitalia, Feminine genitalia, Ambiguous genitalia (it is not clear whether the external genitalia is male or female). […] Puberty: Insufficient development of muscle mass, The lack of development of male voice character, Insufficient growth of hair, beard, genital area and body hair, Insufficient development of the penis and testicles, Longer extremities such as arms and legs compared to the trunk, Enlargement of the breasts (gynecomastia).

• #13 Male Hypogonadism – Genitourinary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/genitourinary-disorders/male-reproductive-endocrinology-and-related-disorders/male-hypogonadism

  Age at onset of testosterone deficiency (congenital, childhood-onset, or adult-onset hypogonadism) dictates the clinical presentation. […] Congenital hypogonadism may be of first-, second-, or third-trimester onset. Congenital hypogonadism of first-trimester onset results in inadequate male sexual differentiation. Complete absence of testosterone effects results in normal-appearing female external genitals. Partial testosterone deficiency results in abnormalities ranging from ambiguous external genitalia to hypospadias. Second- or third-trimester onset of testosterone deficiency results in microphallus and undescended testes. […] Childhood-onset testosterone deficiency is unrecognized until puberty is delayed. Untreated hypogonadism impairs development of secondary sexual characteristics. As adults, affected patients have poor muscle development, a high-pitched voice, a small scrotum, decreased phallic and testicular growth, sparse pubic and axillary hair, and an absence of body hair. They may develop gynecomastia and eunuchoidal body proportions because of delayed fusion of the epiphyses and continued long bone growth.

• #14 Male Hypogonadism in Children – Pediatrics – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/pediatrics/endocrine-disorders-in-children/male-hypogonadism-in-children

  Male hypogonadism is decreased production of testosterone, sperm, or both or, rarely, decreased response to testosterone, resulting in delayed puberty, infertility, or both. […] Clinical presentation depends on whether, when, and how testosterone and sperm production are affected. […] If androgen deficiency or defects in androgen activity occur during the first trimester (12 weeks gestation), differentiation of internal wolffian ducts and external genitals is inadequate. Presentation may range from ambiguous external genitals to normal-appearing female external genitals. Androgen deficiency during the second and third trimesters may cause a microphallus and partially or completely undescended testes. […] Androgen deficiency that develops early in childhood has few consequences, but if it occurs when puberty is expected, secondary sexual development is impaired. Such patients have poor muscle development, a high-pitched voice, inadequate phallic and testicular growth, a small scrotum, sparse pubic and axillary hair, and absent body hair. They may develop gynecomastia and grow to eunuchoidal body proportions (arm span exceeds height by 5 cm; pubic to floor length exceeds crown to pubic length by 5 cm) because fusion of the epiphyses is delayed and long bone growth continues.

• #15 Male Hypogonadism in Children – Children’s Health Issues – MSD Manual Consumer Version

  https://www.msdmanuals.com/home/children-s-health-issues/hormonal-disorders-in-children/male-hypogonadism-in-children

  Hypogonadism is decreased production of testosterone, sperm, or both in males. […] Symptoms vary depending at which age the testosterone deficiency begins. […] When testosterone is lacking, growth and sexual development may be slow, sperm production is low, and the penis may be small. […] Symptoms of hypogonadism vary depending at which age the testosterone deficiency begins. […] In a male fetus, testosterone deficiency before the 12th week of pregnancy causes incomplete development of the genitals. […] If testosterone deficiency develops later in pregnancy, a male fetus may have an abnormally small penis or testes that do not descend into the scrotum. […] A male newborn may have genitals that appear less masculine (undervirilized) or appear more female, sometimes referred to as ambiguous genitalia.

• #16 Male Hypogonadism: 5 Signs to Observe in Teenage Boys

  https://risemenshealth.com/male-hypogonadism-5-signs-to-observe-in-teenage-boys/

  Boys with hypogonadism may experience stunted growth compared to their peers. They may also have a delayed growth spurt or experience a slower growth rate overall. […] During puberty, the penis typically grows due to increased testosterone levels. Boys with hypogonadism may experience a slower or gentler growth of the penis, which can indicate low testosterone levels. […] Hypogonadism in teenage boys can significantly affect physical and emotional development. Observing the signs of hypogonadism and seeking medical attention if necessary is essential.

• #17 Male Hypogonadism – Genitourinary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/genitourinary-disorders/male-reproductive-endocrinology-and-related-disorders/male-hypogonadism

  Age at onset of testosterone deficiency (congenital, childhood-onset, or adult-onset hypogonadism) dictates the clinical presentation. […] Congenital hypogonadism may be of first-, second-, or third-trimester onset. Congenital hypogonadism of first-trimester onset results in inadequate male sexual differentiation. Complete absence of testosterone effects results in normal-appearing female external genitals. Partial testosterone deficiency results in abnormalities ranging from ambiguous external genitalia to hypospadias. Second- or third-trimester onset of testosterone deficiency results in microphallus and undescended testes. […] Childhood-onset testosterone deficiency is unrecognized until puberty is delayed. Untreated hypogonadism impairs development of secondary sexual characteristics. As adults, affected patients have poor muscle development, a high-pitched voice, a small scrotum, decreased phallic and testicular growth, sparse pubic and axillary hair, and an absence of body hair. They may develop gynecomastia and eunuchoidal body proportions because of delayed fusion of the epiphyses and continued long bone growth.

• #18 Male Hypogonadism: 5 Signs to Observe in Teenage Boys

  https://risemenshealth.com/male-hypogonadism-5-signs-to-observe-in-teenage-boys/

  Hypogonadism is a condition that occurs when the testes do not produce enough testosterone, which is a hormone that plays a significant role in male development and reproductive health. It can affect boys and men of all ages, but observing the signs in teenage boys is essential as it can significantly impact their physical and emotional development. […] One of the earliest signs of puberty in boys is the growth of pubic hair. Hypogonadism can cause delayed or absent growth of pubic hair, which can indicate low testosterone levels. […] During puberty, the voice typically deepens due to increased testosterone levels. The process may be delayed or absent in boys with hypogonadism, leading to a high-pitched or unchanged voice. […] Testosterone is also responsible for body hair growth in boys during puberty. Hypogonadism can cause a slow or absent development of body hair, particularly in the chest, armpits, and legs.

• #19 Male Hypogonadism – Genitourinary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/genitourinary-disorders/male-reproductive-endocrinology-and-related-disorders/male-hypogonadism

  Age at onset of testosterone deficiency (congenital, childhood-onset, or adult-onset hypogonadism) dictates the clinical presentation. […] Congenital hypogonadism may be of first-, second-, or third-trimester onset. Congenital hypogonadism of first-trimester onset results in inadequate male sexual differentiation. Complete absence of testosterone effects results in normal-appearing female external genitals. Partial testosterone deficiency results in abnormalities ranging from ambiguous external genitalia to hypospadias. Second- or third-trimester onset of testosterone deficiency results in microphallus and undescended testes. […] Childhood-onset testosterone deficiency is unrecognized until puberty is delayed. Untreated hypogonadism impairs development of secondary sexual characteristics. As adults, affected patients have poor muscle development, a high-pitched voice, a small scrotum, decreased phallic and testicular growth, sparse pubic and axillary hair, and an absence of body hair. They may develop gynecomastia and eunuchoidal body proportions because of delayed fusion of the epiphyses and continued long bone growth.

• #20 Male Hypogonadism: 5 Signs to Observe in Teenage Boys

  https://risemenshealth.com/male-hypogonadism-5-signs-to-observe-in-teenage-boys/

  Hypogonadism is a condition that occurs when the testes do not produce enough testosterone, which is a hormone that plays a significant role in male development and reproductive health. It can affect boys and men of all ages, but observing the signs in teenage boys is essential as it can significantly impact their physical and emotional development. […] One of the earliest signs of puberty in boys is the growth of pubic hair. Hypogonadism can cause delayed or absent growth of pubic hair, which can indicate low testosterone levels. […] During puberty, the voice typically deepens due to increased testosterone levels. The process may be delayed or absent in boys with hypogonadism, leading to a high-pitched or unchanged voice. […] Testosterone is also responsible for body hair growth in boys during puberty. Hypogonadism can cause a slow or absent development of body hair, particularly in the chest, armpits, and legs.

• #21 Male Hypogonadism – Genitourinary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/genitourinary-disorders/male-reproductive-endocrinology-and-related-disorders/male-hypogonadism

  Age at onset of testosterone deficiency (congenital, childhood-onset, or adult-onset hypogonadism) dictates the clinical presentation. […] Congenital hypogonadism may be of first-, second-, or third-trimester onset. Congenital hypogonadism of first-trimester onset results in inadequate male sexual differentiation. Complete absence of testosterone effects results in normal-appearing female external genitals. Partial testosterone deficiency results in abnormalities ranging from ambiguous external genitalia to hypospadias. Second- or third-trimester onset of testosterone deficiency results in microphallus and undescended testes. […] Childhood-onset testosterone deficiency is unrecognized until puberty is delayed. Untreated hypogonadism impairs development of secondary sexual characteristics. As adults, affected patients have poor muscle development, a high-pitched voice, a small scrotum, decreased phallic and testicular growth, sparse pubic and axillary hair, and an absence of body hair. They may develop gynecomastia and eunuchoidal body proportions because of delayed fusion of the epiphyses and continued long bone growth.

• #22 Male Hypogonadism – Genitourinary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/genitourinary-disorders/male-reproductive-endocrinology-and-related-disorders/male-hypogonadism

  Age at onset of testosterone deficiency (congenital, childhood-onset, or adult-onset hypogonadism) dictates the clinical presentation. […] Congenital hypogonadism may be of first-, second-, or third-trimester onset. Congenital hypogonadism of first-trimester onset results in inadequate male sexual differentiation. Complete absence of testosterone effects results in normal-appearing female external genitals. Partial testosterone deficiency results in abnormalities ranging from ambiguous external genitalia to hypospadias. Second- or third-trimester onset of testosterone deficiency results in microphallus and undescended testes. […] Childhood-onset testosterone deficiency is unrecognized until puberty is delayed. Untreated hypogonadism impairs development of secondary sexual characteristics. As adults, affected patients have poor muscle development, a high-pitched voice, a small scrotum, decreased phallic and testicular growth, sparse pubic and axillary hair, and an absence of body hair. They may develop gynecomastia and eunuchoidal body proportions because of delayed fusion of the epiphyses and continued long bone growth.

• #23 Male Hypogonadism – Genitourinary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/genitourinary-disorders/male-reproductive-endocrinology-and-related-disorders/male-hypogonadism

  Age at onset of testosterone deficiency (congenital, childhood-onset, or adult-onset hypogonadism) dictates the clinical presentation. […] Congenital hypogonadism may be of first-, second-, or third-trimester onset. Congenital hypogonadism of first-trimester onset results in inadequate male sexual differentiation. Complete absence of testosterone effects results in normal-appearing female external genitals. Partial testosterone deficiency results in abnormalities ranging from ambiguous external genitalia to hypospadias. Second- or third-trimester onset of testosterone deficiency results in microphallus and undescended testes. […] Childhood-onset testosterone deficiency is unrecognized until puberty is delayed. Untreated hypogonadism impairs development of secondary sexual characteristics. As adults, affected patients have poor muscle development, a high-pitched voice, a small scrotum, decreased phallic and testicular growth, sparse pubic and axillary hair, and an absence of body hair. They may develop gynecomastia and eunuchoidal body proportions because of delayed fusion of the epiphyses and continued long bone growth.

• #24 Hypogonadism | UCI Men’s Health – Male Infertility and Erectile Dysfunction Specialists

  https://ucimenshealth.com/more-services/hypogonadism/

  Hypogonadism is a condition in which the body either doesnt produce enough testosterone or sperm, or both. […] The symptoms of hypogonadism vary depending on when the patient develops the condition. In congenital hypogonadism, the patient will be born with abnormal genitalia; they can be underdeveloped or ambiguous. Some patients are even born with female genitalia. […] If the patient develops hypogonadism in adolescence, the condition may delay puberty or impair their development. In this case, the patient may show the following symptoms: Gynecomastia or development of breast tissue, Little development of muscle mass, Impaired growth of male genitals, Impaired growth of body hair, Excessive growth of the limbs in proportion to the body, No deepening of the voice. […] An adult who develops hypogonadism may show the following symptoms: Decreased muscle mass, Gynecomastia, Osteoporosis, Infertility, Erectile dysfunction, Loss of body and facial hair. […] Some men may also experience symptoms similar to those of women undergoing menopause like hot flashes, fatigue, trouble concentrating, and decreased sex drive.

• #25 Male Hypogonadism – Genitourinary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/genitourinary-disorders/male-reproductive-endocrinology-and-related-disorders/male-hypogonadism

  Age at onset of testosterone deficiency (congenital, childhood-onset, or adult-onset hypogonadism) dictates the clinical presentation. […] Congenital hypogonadism may be of first-, second-, or third-trimester onset. Congenital hypogonadism of first-trimester onset results in inadequate male sexual differentiation. Complete absence of testosterone effects results in normal-appearing female external genitals. Partial testosterone deficiency results in abnormalities ranging from ambiguous external genitalia to hypospadias. Second- or third-trimester onset of testosterone deficiency results in microphallus and undescended testes. […] Childhood-onset testosterone deficiency is unrecognized until puberty is delayed. Untreated hypogonadism impairs development of secondary sexual characteristics. As adults, affected patients have poor muscle development, a high-pitched voice, a small scrotum, decreased phallic and testicular growth, sparse pubic and axillary hair, and an absence of body hair. They may develop gynecomastia and eunuchoidal body proportions because of delayed fusion of the epiphyses and continued long bone growth.

• #26 Male Hypogonadism in Children – Pediatrics – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/pediatrics/endocrine-disorders-in-children/male-hypogonadism-in-children

  Male hypogonadism is decreased production of testosterone, sperm, or both or, rarely, decreased response to testosterone, resulting in delayed puberty, infertility, or both. […] Clinical presentation depends on whether, when, and how testosterone and sperm production are affected. […] If androgen deficiency or defects in androgen activity occur during the first trimester (12 weeks gestation), differentiation of internal wolffian ducts and external genitals is inadequate. Presentation may range from ambiguous external genitals to normal-appearing female external genitals. Androgen deficiency during the second and third trimesters may cause a microphallus and partially or completely undescended testes. […] Androgen deficiency that develops early in childhood has few consequences, but if it occurs when puberty is expected, secondary sexual development is impaired. Such patients have poor muscle development, a high-pitched voice, inadequate phallic and testicular growth, a small scrotum, sparse pubic and axillary hair, and absent body hair. They may develop gynecomastia and grow to eunuchoidal body proportions (arm span exceeds height by 5 cm; pubic to floor length exceeds crown to pubic length by 5 cm) because fusion of the epiphyses is delayed and long bone growth continues.

• #27 Testosterone Deficiency / Low (Hypogonadism): Causes, Symptoms, Diagnosis and Treatment

  https://dreminozbek.com/en/testosterone-deficiency-low-hypogonadism-causes-symptoms-diagnosis-and-treatment/

  Hypogonadism can begin during fetal development, before puberty or later in adulthood. Symptoms of testosterone deficiency vary according to the age at which the disease occurs. […] Symptoms of hypogonadism developing in the fetal period vary according to the degree of T deficiency. Although the child is genetically male, there is a problem in the genital organs; Insufficient development of male external genitalia, Feminine genitalia, Ambiguous genitalia (it is not clear whether the external genitalia is male or female). […] Puberty: Insufficient development of muscle mass, The lack of development of male voice character, Insufficient growth of hair, beard, genital area and body hair, Insufficient development of the penis and testicles, Longer extremities such as arms and legs compared to the trunk, Enlargement of the breasts (gynecomastia).

• #28 Male Hypogonadism: 5 Signs to Observe in Teenage Boys

  https://risemenshealth.com/male-hypogonadism-5-signs-to-observe-in-teenage-boys/

  Boys with hypogonadism may experience stunted growth compared to their peers. They may also have a delayed growth spurt or experience a slower growth rate overall. […] During puberty, the penis typically grows due to increased testosterone levels. Boys with hypogonadism may experience a slower or gentler growth of the penis, which can indicate low testosterone levels. […] Hypogonadism in teenage boys can significantly affect physical and emotional development. Observing the signs of hypogonadism and seeking medical attention if necessary is essential.

• #29 Male Hypogonadism – Genitourinary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/genitourinary-disorders/male-reproductive-endocrinology-and-related-disorders/male-hypogonadism

  Adult-onset testosterone deficiency has varied manifestations depending on the degree and duration of the deficiency. Decreased libido; erectile dysfunction; decline in cognitive skills, such as visual-spatial interpretation; sleep disturbances; vasomotor instability; and mood changes, such as depression and anger, are common. Decreased lean body mass, increased visceral fat, testicular atrophy, osteopenia, gynecomastia, and sparse body hair typically take months to years to develop. Testosterone deficiency is a risk factor for cardiovascular disease.

• #30 Male hypogonadism: Symptoms, causes, and treatment

  https://www.medicalnewstoday.com/articles/307634

  Male hypogonadism, also known as testosterone deficiency, describes when the testes are unable to produce the male sex hormone testosterone, sperm, or both. […] The signs and symptoms depend on when it starts, how severe the deficiency is, and whether or not there is a decrease in the major functions of the testes. […] If hypogonadism occurs before puberty, puberty does not progress. If it occurs after puberty, there may be infertility and sexual dysfunction. […] In adult men, symptoms begin within a few weeks of the onset of testosterone deficiency. […] A lack of testosterone can cause a wide range of symptoms. […] Symptoms of adult-onset hypogonadism include: erectile dysfunction, low sperm count, depressed mood, decreased libido, lethargy, sleep disturbances, decreased muscle mass and strength, loss of body hair (pubic, axillary, facial), osteoporosis and decreased bone mineral density, increased body fat, breast discomfort and enlargement, hot flashes, sweating, poor concentration and decreased energy.

• #31 Male Hypogonadism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK532933/

  Male hypogonadism, acquired or congenital, can be caused by defects that interfere with the hypothalamic-pituitary-testicular axis. Symptoms highly suggestive of hypogonadism include decreased spontaneous erections, decreased nocturnal penile tumescence, decreased libido, and reduced testicular volume. […] Symptoms highly suggestive of hypogonadism include decreased spontaneous erections, reduced nocturnal penile tumescence, infrequent morning erections, low libido, unexplained fatigue, and smaller testicular volume. […] Symptoms highly suggestive of androgen deficiency in men include reduced sexual desire, decreased spontaneous erections, fatigue, lethargy, loss of axillary and pubic hair, visual field changes (such as bitemporal hemianopsia), loss of smell (anosmia), declining or small testicular volume, hot flashes, and infertility with low or absent sperm counts. Other less suggestive symptoms include depressed mood, irritability, poor concentration, increased body fat, decreased physical performance, lower muscle mass, reduced endurance, weight loss, reduced energy, and loss of appetite.

• #32 Low Testosterone (Low T): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/15603-low-testosterone-male-hypogonadism

  The symptoms of low testosterone in adult men include reduced sex drive, erectile dysfunction, fatigue and more. […] Symptoms that highly suggest low testosterone in men include: Reduced sex drive. Erectile dysfunction. Loss of armpit and pubic hair. Shrinking testicles. Hot flashes. Low or zero sperm count (azoospermia), which causes male infertility. […] Other symptoms of low testosterone in men include: Depressed mood. Difficulties with concentration and memory. Increased body fat. Enlarged male breast tissue (gynecomastia). Decrease in muscle strength and mass. Decrease in endurance. […] Late-onset hypogonadism (LOH) is a type of secondary male hypogonadism that results from normal aging. As males age they have a deterioration of hypothalamic-pituitary function and Leydig cell function that decrease testosterone and/or sperm production.

• #33 Male Hypogonadism: Symptoms, Causes, and Treatment Options – The Kingsley Clinic

  https://thekingsleyclinic.com/resources/male-hypogonadism-symptoms-causes-and-treatment-options/

  Male hypogonadism occurs when the testes fail to produce sufficient testosterone, a hormone essential for male growth and development. […] The progression of male hypogonadism varies depending on the underlying cause. In some cases, it develops gradually, while in others, it can occur suddenly. Symptoms often worsen as testosterone levels decline. Common symptoms include fatigue, reduced libido, erectile dysfunction, and loss of muscle mass. […] Decreased libido, or reduced interest in sexual activity, is one of the most common symptoms of male hypogonadism, affecting 70-80% of patients. […] Erectile dysfunction (ED) affects about 50-60% of men with hypogonadism. […] Fatigue is reported in 60-70% of men with hypogonadism. […] Depression occurs in 30-40% of men with hypogonadism. […] Reduced muscle mass is seen in 40-50% of men with hypogonadism.

• #34 Do I Have Low Testosterone? 13 Symptoms to Look for

  https://honehealth.com/edge/symptoms-of-low-testosterone-in-men/?srsltid=AfmBOop13vO8lVp1hwjMp–wzxCpYz84BUiDUTEga0T9yQJokTLB4BYt

  A drastic drop in testosterone can quickly turn your sex drive into a sex putter. Study after study indicates that decreased libido is the symptom that is most indicative of testosterone deficiency, says Calvert. This is also an area where most men notice an improvement when they get on treatment. […] Testosterone stimulates the growth of muscles and increases muscle strength, says Calvert. Your muscle cells have receptors called androgen receptors. When testosterone binds to the receptors, it helps your muscles grow. But when T levels flag, the muscle can start to degrade. […] If youre noticing its hard to get and keep an erection, its worth getting your testosterone levels checked. […] The relationship isnt completely understood, but researchers suspect that testosterone acts as a vasodilator, allowing more blood flow into the penis, says Calvert. Without enough testosterone, blood may not be able to enter the penis and allow it to get rigid enough for sex.

• #35 Male Hypogonadism: Symptoms, Causes, and Treatment Options – The Kingsley Clinic

  https://thekingsleyclinic.com/resources/male-hypogonadism-symptoms-causes-and-treatment-options/

  Male hypogonadism occurs when the testes fail to produce sufficient testosterone, a hormone essential for male growth and development. […] The progression of male hypogonadism varies depending on the underlying cause. In some cases, it develops gradually, while in others, it can occur suddenly. Symptoms often worsen as testosterone levels decline. Common symptoms include fatigue, reduced libido, erectile dysfunction, and loss of muscle mass. […] Decreased libido, or reduced interest in sexual activity, is one of the most common symptoms of male hypogonadism, affecting 70-80% of patients. […] Erectile dysfunction (ED) affects about 50-60% of men with hypogonadism. […] Fatigue is reported in 60-70% of men with hypogonadism. […] Depression occurs in 30-40% of men with hypogonadism. […] Reduced muscle mass is seen in 40-50% of men with hypogonadism.

• #36 7 Symptoms of Low Testosterone in Men

  https://www.rupahealth.com/post/low-testosterone-symptoms

  Low testosterone, or hypogonadism, can manifest through a variety of symptoms that affect physical, sexual, and psychological health. Common symptoms include: […] Low testosterone levels are often associated with a decrease in sexual desire. This relationship is evident in both reviews and epidemiological studies, where testosterone replacement therapy has been shown to help restore sexual desire in men with hypogonadism. […] Testosterone deficiency is linked to erectile dysfunction (ED), as testosterone plays a role in the erectile process. Studies indicate that testosterone replacement can support erectile function, particularly in men who do not respond to phosphodiesterase type 5 inhibitors. […] Testosterone is important for maintaining muscle mass. Low levels of testosterone can lead to a reduction in muscle mass and strength, which is often observed in men with hypogonadism.

• #37 Hypogonadism in men – Symptoms, diagnosis and treatment | BMJ Best Practice

  https://bestpractice.bmj.com/topics/en-us/1093

  Hypogonadism in men may present with reproductive/sexual clinical features (e.g., incomplete pubertal development, infertility, gynaecomastia), as well as non-reproductive features (e.g., fatigue, osteoporosis, loss of motivation or concentration, irritability, low or labile mood, body image concerns). […] Patients may have additional symptoms due to mass effects when caused by large parasellar lesions (e.g., headache, peripheral visual disturbance), or may have signs or symptoms of other hormone deficiencies. […] Key diagnostic factors include decreased libido, loss of spontaneous morning erections, erectile dysfunction, gynaecomastia, infertility, micropenis, small testes, bifid or hypoplastic scrotum, cryptorchidism, especially if bilateral, segmental dysproportion, bitemporal hemianopia, low trauma fractures, loss of height, and anosmia.

• #38

  https://journals.lww.com/japtr/fulltext/2010/01030/male_hypogonadism__symptoms_and_treatment.5.aspx

  Male hypogonadism is characterized by a deficiency in testosterone a critical hormone for sexual, cognitive, and body function and development. Clinically low testosterone levels can lead to the absence of secondary sex characteristics, infertility, muscle wasting, and other abnormalities. […] Hypogonadism is characterized by serum testosterone levels 300 ng/dL in combination with at least one clinical sign or symptom. Signs of hypogonadism include absence or regression of secondary sex characteristics, anemia, muscle wasting, reduced bone mass or bone mineral density, oligospermia, and abdominal adiposity. Symptoms of post pubescent hypogonadism include sexual dysfunction (erectile dysfunction, reduced libido, diminished penile sensation, difficulty attaining orgasm, and reduced ejaculate), reduced energy and stamina, depressed mood, increased irritability, difficulty concentrating, changes in cholesterol levels, anemia, osteoporosis, and hot flushes. In the prepubertal male, if treatment is not initiated, signs and symptoms include sparse body hair and delayed epiphyseal closure. […] Recent studies have found that testosterone production slowly decreases as a result of aging, although the rate of decline varies. […] The Baltimore Longitudinal Study of Aging reported that approximately 20% of men in their 60s and 50% of men in their 80s are hypogonadal.

• #39

  https://journals.lww.com/japtr/fulltext/2010/01030/male_hypogonadism__symptoms_and_treatment.5.aspx

  Male hypogonadism is characterized by a deficiency in testosterone a critical hormone for sexual, cognitive, and body function and development. Clinically low testosterone levels can lead to the absence of secondary sex characteristics, infertility, muscle wasting, and other abnormalities. […] Hypogonadism is characterized by serum testosterone levels 300 ng/dL in combination with at least one clinical sign or symptom. Signs of hypogonadism include absence or regression of secondary sex characteristics, anemia, muscle wasting, reduced bone mass or bone mineral density, oligospermia, and abdominal adiposity. Symptoms of post pubescent hypogonadism include sexual dysfunction (erectile dysfunction, reduced libido, diminished penile sensation, difficulty attaining orgasm, and reduced ejaculate), reduced energy and stamina, depressed mood, increased irritability, difficulty concentrating, changes in cholesterol levels, anemia, osteoporosis, and hot flushes. In the prepubertal male, if treatment is not initiated, signs and symptoms include sparse body hair and delayed epiphyseal closure. […] Recent studies have found that testosterone production slowly decreases as a result of aging, although the rate of decline varies. […] The Baltimore Longitudinal Study of Aging reported that approximately 20% of men in their 60s and 50% of men in their 80s are hypogonadal.

• #40 Male hypogonadism – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/male-hypogonadism/symptoms-causes/syc-20354881

  Male hypogonadism is a condition in which the body doesn’t produce enough of the hormone that plays a key role in masculine growth and development during puberty (testosterone) or enough sperm or both. […] Hypogonadism can begin during fetal development, before puberty or during adulthood. Signs and symptoms depend on when the condition develops. […] Male hypogonadism can delay puberty or cause incomplete or lack of normal development. It can hamper: Development of muscle mass, Voice deepening, Growth of body and facial hair, Growth of the penis and testicles. […] In adult males, hypogonadism can alter certain masculine physical characteristics and impair normal reproductive function. Early signs and symptoms might include: Decreased sex drive, Decreased energy, Depression. […] Over time, men with hypogonadism can develop: Erectile dysfunction, Infertility, Decrease in hair growth on the face and body, Decrease in muscle mass, Development of breast tissue (gynecomastia), Loss of bone mass (osteoporosis). […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: Difficulty concentrating, Hot flashes.

• #41 Low Testosterone (Low T): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/15603-low-testosterone-male-hypogonadism

  The symptoms of low testosterone in adult men include reduced sex drive, erectile dysfunction, fatigue and more. […] Symptoms that highly suggest low testosterone in men include: Reduced sex drive. Erectile dysfunction. Loss of armpit and pubic hair. Shrinking testicles. Hot flashes. Low or zero sperm count (azoospermia), which causes male infertility. […] Other symptoms of low testosterone in men include: Depressed mood. Difficulties with concentration and memory. Increased body fat. Enlarged male breast tissue (gynecomastia). Decrease in muscle strength and mass. Decrease in endurance. […] Late-onset hypogonadism (LOH) is a type of secondary male hypogonadism that results from normal aging. As males age they have a deterioration of hypothalamic-pituitary function and Leydig cell function that decrease testosterone and/or sperm production.

• #42 Male hypogonadism – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/male-hypogonadism/symptoms-causes/syc-20354881

  Male hypogonadism is a condition in which the body doesn’t produce enough of the hormone that plays a key role in masculine growth and development during puberty (testosterone) or enough sperm or both. […] Hypogonadism can begin during fetal development, before puberty or during adulthood. Signs and symptoms depend on when the condition develops. […] Male hypogonadism can delay puberty or cause incomplete or lack of normal development. It can hamper: Development of muscle mass, Voice deepening, Growth of body and facial hair, Growth of the penis and testicles. […] In adult males, hypogonadism can alter certain masculine physical characteristics and impair normal reproductive function. Early signs and symptoms might include: Decreased sex drive, Decreased energy, Depression. […] Over time, men with hypogonadism can develop: Erectile dysfunction, Infertility, Decrease in hair growth on the face and body, Decrease in muscle mass, Development of breast tissue (gynecomastia), Loss of bone mass (osteoporosis). […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: Difficulty concentrating, Hot flashes.

• #43 Male hypogonadism: Symptoms, causes, and treatment

  https://www.medicalnewstoday.com/articles/307634

  Male hypogonadism, also known as testosterone deficiency, describes when the testes are unable to produce the male sex hormone testosterone, sperm, or both. […] The signs and symptoms depend on when it starts, how severe the deficiency is, and whether or not there is a decrease in the major functions of the testes. […] If hypogonadism occurs before puberty, puberty does not progress. If it occurs after puberty, there may be infertility and sexual dysfunction. […] In adult men, symptoms begin within a few weeks of the onset of testosterone deficiency. […] A lack of testosterone can cause a wide range of symptoms. […] Symptoms of adult-onset hypogonadism include: erectile dysfunction, low sperm count, depressed mood, decreased libido, lethargy, sleep disturbances, decreased muscle mass and strength, loss of body hair (pubic, axillary, facial), osteoporosis and decreased bone mineral density, increased body fat, breast discomfort and enlargement, hot flashes, sweating, poor concentration and decreased energy.

• #44 Male Hypogonadism: Symptoms, Causes, and Treatment Options – The Kingsley Clinic

  https://thekingsleyclinic.com/resources/male-hypogonadism-symptoms-causes-and-treatment-options/

  Male hypogonadism occurs when the testes fail to produce sufficient testosterone, a hormone essential for male growth and development. […] The progression of male hypogonadism varies depending on the underlying cause. In some cases, it develops gradually, while in others, it can occur suddenly. Symptoms often worsen as testosterone levels decline. Common symptoms include fatigue, reduced libido, erectile dysfunction, and loss of muscle mass. […] Decreased libido, or reduced interest in sexual activity, is one of the most common symptoms of male hypogonadism, affecting 70-80% of patients. […] Erectile dysfunction (ED) affects about 50-60% of men with hypogonadism. […] Fatigue is reported in 60-70% of men with hypogonadism. […] Depression occurs in 30-40% of men with hypogonadism. […] Reduced muscle mass is seen in 40-50% of men with hypogonadism.

• #45 7 Symptoms of Low Testosterone in Men

  https://www.rupahealth.com/post/low-testosterone-symptoms

  Low testosterone, or hypogonadism, can manifest through a variety of symptoms that affect physical, sexual, and psychological health. Common symptoms include: […] Low testosterone levels are often associated with a decrease in sexual desire. This relationship is evident in both reviews and epidemiological studies, where testosterone replacement therapy has been shown to help restore sexual desire in men with hypogonadism. […] Testosterone deficiency is linked to erectile dysfunction (ED), as testosterone plays a role in the erectile process. Studies indicate that testosterone replacement can support erectile function, particularly in men who do not respond to phosphodiesterase type 5 inhibitors. […] Testosterone is important for maintaining muscle mass. Low levels of testosterone can lead to a reduction in muscle mass and strength, which is often observed in men with hypogonadism.

• #46 Male Hypogonadism: Symptoms, Causes, and Treatment Options – The Kingsley Clinic

  https://thekingsleyclinic.com/resources/male-hypogonadism-symptoms-causes-and-treatment-options/

  Increased body fat, particularly around the abdomen, is observed in 50-60% of men with hypogonadism. […] Hot flashes are experienced by 20-30% of men with hypogonadism, particularly those with more severe testosterone deficiencies. […] Infertility affects 30-40% of men with hypogonadism. […] Decreased bone density, or osteoporosis, is seen in 20-30% of men with hypogonadism. […] Gynecomastia, or the development of breast tissue in men, occurs in 10-20% of men with hypogonadism.

• #47 Male Hypogonadism: Causes, Symptoms, and Treatment

  https://www.verywellhealth.com/male-hypogonadism-8651069

  In addition to the common signs and symptoms of hypogonadism, persistently low testosterone levels can lead to longer-term complications like: Muscle atrophy (muscle wasting), Anemia (low numbers of healthy red blood cells), Osteoporosis (porous bones due to bone mineral loss), Increased body fat and central obesity, An increased risk of metabolic syndrome and type 2 diabetes, An increased risk of heart disease due to obesity, type 2 diabetes, and metabolic syndrome. […] Male hypogonadism is diagnosed based on low testosterone blood levels and the appearance of symptoms. […] Testosterone replacement therapy (TRT) is the primary form of treatment for male hypogonadism. TRT is used to normalize testosterone levels with the aim of: Improving libido, sexual function, energy levels, well-being, and moods, Promoting and maintaining secondary male characteristics (virilization), Increasing bone density and preventing osteoporosis, Improving fertility.

• #48 Male Hypogonadism: Symptoms, Causes, and Treatment Options – The Kingsley Clinic

  https://thekingsleyclinic.com/resources/male-hypogonadism-symptoms-causes-and-treatment-options/

  Increased body fat, particularly around the abdomen, is observed in 50-60% of men with hypogonadism. […] Hot flashes are experienced by 20-30% of men with hypogonadism, particularly those with more severe testosterone deficiencies. […] Infertility affects 30-40% of men with hypogonadism. […] Decreased bone density, or osteoporosis, is seen in 20-30% of men with hypogonadism. […] Gynecomastia, or the development of breast tissue in men, occurs in 10-20% of men with hypogonadism.

• #49 Do I Have Low Testosterone? 13 Symptoms to Look for

  https://honehealth.com/edge/symptoms-of-low-testosterone-in-men/?srsltid=AfmBOop13vO8lVp1hwjMp–wzxCpYz84BUiDUTEga0T9yQJokTLB4BYt

  If you notice that youre feeling depressed or irritable without reason, it could be a symptom of low testosterone. […] Many men with diagnosed testosterone deficiency notice a dramatic improvement in their mood after starting testosterone replacement treatment, says Calvert. […] While you can blame forgetfulness or not feeling as sharp as you once were on getting older, these could also be signs that your testosterone is low. […] You already know that without enough testosterone, fat-burning muscles cant grow, and any excess calories you eat risk being stored as fat. […] If you do put on excess weight, you may find it in an unwanted area: your chest. The technical term for breast growth in men is gynecomastia, and can be related to an increased level of estrogen in comparison to testosterone, says Calvert.

• #50 Male hypogonadism – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/male-hypogonadism/symptoms-causes/syc-20354881

  Male hypogonadism is a condition in which the body doesn’t produce enough of the hormone that plays a key role in masculine growth and development during puberty (testosterone) or enough sperm or both. […] Hypogonadism can begin during fetal development, before puberty or during adulthood. Signs and symptoms depend on when the condition develops. […] Male hypogonadism can delay puberty or cause incomplete or lack of normal development. It can hamper: Development of muscle mass, Voice deepening, Growth of body and facial hair, Growth of the penis and testicles. […] In adult males, hypogonadism can alter certain masculine physical characteristics and impair normal reproductive function. Early signs and symptoms might include: Decreased sex drive, Decreased energy, Depression. […] Over time, men with hypogonadism can develop: Erectile dysfunction, Infertility, Decrease in hair growth on the face and body, Decrease in muscle mass, Development of breast tissue (gynecomastia), Loss of bone mass (osteoporosis). […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: Difficulty concentrating, Hot flashes.

• #51 Hypogonadism in males

  https://dermnetnz.org/topics/hypogonadism-in-males

  Hypogonadism in males refers to diminished testicular function a reduction in sperm production and in testosterone. […] The clinical features of hypogonadism depend on the patient’s age at presentation. […] Hypogonadism pre-puberty may be diagnosed by the failure to undergo or complete puberty. The boy may have a young appearance, lack pubic hair, have small genitalia and testes, his voice may fail to break, and he may have difficulty in gaining muscle. […] After the completion of puberty, the features of hypogonadism include decreased libido, erectile dysfunction, osteoporosis, depression, gynaecomastia, shrinking of the testes, and infertility. After some years of testosterone deficiency, decreased muscle mass and body hair may be evident. […] Androgen deficiency results in: Dry, thin, and wrinkled skin, Lack of hair growth on the chest, axilla, face, and genitals, Lack of genital pigmentation, Gynaecomastia, Reduced incidence of acne. […] Effective testosterone replacement in men with hypogonadism has been showed to maintain secondary sexual characteristics, increase libido, muscle strength, fat-free mass, and bone density.

• #52 Male Hypogonadism: Symptoms, Causes, and Treatment Options – The Kingsley Clinic

  https://thekingsleyclinic.com/resources/male-hypogonadism-symptoms-causes-and-treatment-options/

  Increased body fat, particularly around the abdomen, is observed in 50-60% of men with hypogonadism. […] Hot flashes are experienced by 20-30% of men with hypogonadism, particularly those with more severe testosterone deficiencies. […] Infertility affects 30-40% of men with hypogonadism. […] Decreased bone density, or osteoporosis, is seen in 20-30% of men with hypogonadism. […] Gynecomastia, or the development of breast tissue in men, occurs in 10-20% of men with hypogonadism.

• #53 7 Symptoms of Low Testosterone in Men

  https://www.rupahealth.com/post/low-testosterone-symptoms

  Men with low testosterone levels often experience an increase in body fat. This is due to the hormone’s role in regulating fat distribution and metabolism. […] Testosterone is important for bone health, and low levels can result in decreased bone density, increasing the risk of osteoporosis and fractures. Testosterone acts directly on osteoblasts, promoting bone formation and indirectly by converting to estrogen, which helps maintain bone density. […] Low testosterone levels are associated with mood changes, including feelings of depression and irritability. Testosterone replacement therapy has been shown to help improve mood symptoms in some men with hypogonadism. […] Fatigue is a common symptom of low testosterone. Men with hypogonadism often report persistent tiredness and a lack of energy, which can be alleviated with appropriate testosterone therapy.

• #54 Hypogonadism in men – Symptoms, diagnosis and treatment | BMJ Best Practice

  https://bestpractice.bmj.com/topics/en-us/1093

  Hypogonadism in men may present with reproductive/sexual clinical features (e.g., incomplete pubertal development, infertility, gynaecomastia), as well as non-reproductive features (e.g., fatigue, osteoporosis, loss of motivation or concentration, irritability, low or labile mood, body image concerns). […] Patients may have additional symptoms due to mass effects when caused by large parasellar lesions (e.g., headache, peripheral visual disturbance), or may have signs or symptoms of other hormone deficiencies. […] Key diagnostic factors include decreased libido, loss of spontaneous morning erections, erectile dysfunction, gynaecomastia, infertility, micropenis, small testes, bifid or hypoplastic scrotum, cryptorchidism, especially if bilateral, segmental dysproportion, bitemporal hemianopia, low trauma fractures, loss of height, and anosmia.

• #55 Low Testosterone (Low T): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/15603-low-testosterone-male-hypogonadism

  The symptoms of low testosterone in adult men include reduced sex drive, erectile dysfunction, fatigue and more. […] Symptoms that highly suggest low testosterone in men include: Reduced sex drive. Erectile dysfunction. Loss of armpit and pubic hair. Shrinking testicles. Hot flashes. Low or zero sperm count (azoospermia), which causes male infertility. […] Other symptoms of low testosterone in men include: Depressed mood. Difficulties with concentration and memory. Increased body fat. Enlarged male breast tissue (gynecomastia). Decrease in muscle strength and mass. Decrease in endurance. […] Late-onset hypogonadism (LOH) is a type of secondary male hypogonadism that results from normal aging. As males age they have a deterioration of hypothalamic-pituitary function and Leydig cell function that decrease testosterone and/or sperm production.

• #56 Hypogonadism in males

  https://dermnetnz.org/topics/hypogonadism-in-males

  Hypogonadism in males refers to diminished testicular function a reduction in sperm production and in testosterone. […] The clinical features of hypogonadism depend on the patient’s age at presentation. […] Hypogonadism pre-puberty may be diagnosed by the failure to undergo or complete puberty. The boy may have a young appearance, lack pubic hair, have small genitalia and testes, his voice may fail to break, and he may have difficulty in gaining muscle. […] After the completion of puberty, the features of hypogonadism include decreased libido, erectile dysfunction, osteoporosis, depression, gynaecomastia, shrinking of the testes, and infertility. After some years of testosterone deficiency, decreased muscle mass and body hair may be evident. […] Androgen deficiency results in: Dry, thin, and wrinkled skin, Lack of hair growth on the chest, axilla, face, and genitals, Lack of genital pigmentation, Gynaecomastia, Reduced incidence of acne. […] Effective testosterone replacement in men with hypogonadism has been showed to maintain secondary sexual characteristics, increase libido, muscle strength, fat-free mass, and bone density.

• #57 Male Hypogonadism: Symptoms, Causes, and Treatment Options – The Kingsley Clinic

  https://thekingsleyclinic.com/resources/male-hypogonadism-symptoms-causes-and-treatment-options/

  Increased body fat, particularly around the abdomen, is observed in 50-60% of men with hypogonadism. […] Hot flashes are experienced by 20-30% of men with hypogonadism, particularly those with more severe testosterone deficiencies. […] Infertility affects 30-40% of men with hypogonadism. […] Decreased bone density, or osteoporosis, is seen in 20-30% of men with hypogonadism. […] Gynecomastia, or the development of breast tissue in men, occurs in 10-20% of men with hypogonadism.

• #58 Do I Have Low Testosterone? 13 Symptoms to Look for

  https://honehealth.com/edge/symptoms-of-low-testosterone-in-men/?srsltid=AfmBOop13vO8lVp1hwjMp–wzxCpYz84BUiDUTEga0T9yQJokTLB4BYt

  Losing facial and body hair can also be a symptom of low testosterone in men. […] This isnt just something women experience during menopause. Men, especially those with low T, can get hot flashes, too. […] Its ironic because low testosterone can lead to insomnia and insomnia can lead to low testosterone, Staheli notes. […] Fatigue is a common sign of low testosterone. You might feel like you just dont have the energy that youre used to. Or you might be incredibly tired, all the time. […] Men with low T may be more prone to broken bones and osteoporosis. […] Another way low T can make you feel tired and weak is by causing anemia, a condition in which you lack enough healthy red blood cells to carry adequate oxygen to your organs and tissues. […] When T levels decrease below 300 ng/dL and start causing symptoms, its called hypogonadism.

• #59 How to manage low testosterone level in men: a guide for primary care | British Journal of General Practice

  https://bjgp.org/content/70/696/364

  Male hypogonadism is a clinical syndrome characterised by testosterone deficiency and impaired spermatogenesis; due either to diseases of the hypothalamus or pituitary gland, or of the testes themselves. The diagnosis requires the presence of clinical features consistent with lack of testosterone plus the finding of persistent and unequivocally low serum testosterone levels. Failure to recognise and treat men with hypogonadism may predispose them to long-term health problems, such as anaemia, osteoporosis, depression, or sexual dysfunction. […] Clinical features of hypogonadism are not limited to sexual symptoms reduced libido, erectile dysfunction (ED), and loss of waking erections. Anaemia, osteoporosis, and vasomotor sweating or flushing are frequently present; indeed, older men may not volunteer sexual symptoms, having ascribed them to ageing.

• #60 Do I Have Low Testosterone? 13 Symptoms to Look for

  https://honehealth.com/edge/symptoms-of-low-testosterone-in-men/?srsltid=AfmBOop13vO8lVp1hwjMp–wzxCpYz84BUiDUTEga0T9yQJokTLB4BYt

  Losing facial and body hair can also be a symptom of low testosterone in men. […] This isnt just something women experience during menopause. Men, especially those with low T, can get hot flashes, too. […] Its ironic because low testosterone can lead to insomnia and insomnia can lead to low testosterone, Staheli notes. […] Fatigue is a common sign of low testosterone. You might feel like you just dont have the energy that youre used to. Or you might be incredibly tired, all the time. […] Men with low T may be more prone to broken bones and osteoporosis. […] Another way low T can make you feel tired and weak is by causing anemia, a condition in which you lack enough healthy red blood cells to carry adequate oxygen to your organs and tissues. […] When T levels decrease below 300 ng/dL and start causing symptoms, its called hypogonadism.

• #61 Male hypogonadism – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/male-hypogonadism/symptoms-causes/syc-20354881

  Male hypogonadism is a condition in which the body doesn’t produce enough of the hormone that plays a key role in masculine growth and development during puberty (testosterone) or enough sperm or both. […] Hypogonadism can begin during fetal development, before puberty or during adulthood. Signs and symptoms depend on when the condition develops. […] Male hypogonadism can delay puberty or cause incomplete or lack of normal development. It can hamper: Development of muscle mass, Voice deepening, Growth of body and facial hair, Growth of the penis and testicles. […] In adult males, hypogonadism can alter certain masculine physical characteristics and impair normal reproductive function. Early signs and symptoms might include: Decreased sex drive, Decreased energy, Depression. […] Over time, men with hypogonadism can develop: Erectile dysfunction, Infertility, Decrease in hair growth on the face and body, Decrease in muscle mass, Development of breast tissue (gynecomastia), Loss of bone mass (osteoporosis). […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: Difficulty concentrating, Hot flashes.

• #62 Male hypogonadism | Health Library | Memorial Health System

  https://www.mhsystem.org/health-library/con-20212413/

  Over time, men with hypogonadism can develop: Erectile dysfunction, Infertility, Decrease in hair growth on the face and body, Decrease in muscle mass, Development of breast tissue (gynecomastia), Loss of bone mass (osteoporosis). […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: Difficulty concentrating, Hot flashes. […] The complications of untreated hypogonadism differ depending on when it develops during fetal development, puberty or adulthood. Complications might include: Abnormal genitalia, Enlarged male breasts (gynecomastia), Infertility, Erectile dysfunction, Osteoporosis, Poor self-image. […] Testosterone replacement can raise testosterone levels and help ease the symptoms of male hypogonadism. These include less desire for sex, less energy, less facial and body hair, and loss of muscle mass and bone mass. […] Treatment of delayed puberty in boys depends on the cause. Three to six months of testosterone shots can help start puberty. The testosterone can help increase muscle mass, beard and pubic hair growth, and growth of the penis.

• #63 Male Hypogonadism: Symptoms, Causes, and Treatment Options – The Kingsley Clinic

  https://thekingsleyclinic.com/resources/male-hypogonadism-symptoms-causes-and-treatment-options/

  Male hypogonadism occurs when the testes fail to produce sufficient testosterone, a hormone essential for male growth and development. […] The progression of male hypogonadism varies depending on the underlying cause. In some cases, it develops gradually, while in others, it can occur suddenly. Symptoms often worsen as testosterone levels decline. Common symptoms include fatigue, reduced libido, erectile dysfunction, and loss of muscle mass. […] Decreased libido, or reduced interest in sexual activity, is one of the most common symptoms of male hypogonadism, affecting 70-80% of patients. […] Erectile dysfunction (ED) affects about 50-60% of men with hypogonadism. […] Fatigue is reported in 60-70% of men with hypogonadism. […] Depression occurs in 30-40% of men with hypogonadism. […] Reduced muscle mass is seen in 40-50% of men with hypogonadism.

• #64 Do I Have Low Testosterone? 13 Symptoms to Look for

  https://honehealth.com/edge/symptoms-of-low-testosterone-in-men/?srsltid=AfmBOop13vO8lVp1hwjMp–wzxCpYz84BUiDUTEga0T9yQJokTLB4BYt

  Losing facial and body hair can also be a symptom of low testosterone in men. […] This isnt just something women experience during menopause. Men, especially those with low T, can get hot flashes, too. […] Its ironic because low testosterone can lead to insomnia and insomnia can lead to low testosterone, Staheli notes. […] Fatigue is a common sign of low testosterone. You might feel like you just dont have the energy that youre used to. Or you might be incredibly tired, all the time. […] Men with low T may be more prone to broken bones and osteoporosis. […] Another way low T can make you feel tired and weak is by causing anemia, a condition in which you lack enough healthy red blood cells to carry adequate oxygen to your organs and tissues. […] When T levels decrease below 300 ng/dL and start causing symptoms, its called hypogonadism.

• #65 Male Hypogonadism: Symptoms, Causes, and Treatment Options – The Kingsley Clinic

  https://thekingsleyclinic.com/resources/male-hypogonadism-symptoms-causes-and-treatment-options/

  Male hypogonadism occurs when the testes fail to produce sufficient testosterone, a hormone essential for male growth and development. […] The progression of male hypogonadism varies depending on the underlying cause. In some cases, it develops gradually, while in others, it can occur suddenly. Symptoms often worsen as testosterone levels decline. Common symptoms include fatigue, reduced libido, erectile dysfunction, and loss of muscle mass. […] Decreased libido, or reduced interest in sexual activity, is one of the most common symptoms of male hypogonadism, affecting 70-80% of patients. […] Erectile dysfunction (ED) affects about 50-60% of men with hypogonadism. […] Fatigue is reported in 60-70% of men with hypogonadism. […] Depression occurs in 30-40% of men with hypogonadism. […] Reduced muscle mass is seen in 40-50% of men with hypogonadism.

• #66 Do I Have Low Testosterone? 13 Symptoms to Look for

  https://honehealth.com/edge/symptoms-of-low-testosterone-in-men/?srsltid=AfmBOop13vO8lVp1hwjMp–wzxCpYz84BUiDUTEga0T9yQJokTLB4BYt

  If you notice that youre feeling depressed or irritable without reason, it could be a symptom of low testosterone. […] Many men with diagnosed testosterone deficiency notice a dramatic improvement in their mood after starting testosterone replacement treatment, says Calvert. […] While you can blame forgetfulness or not feeling as sharp as you once were on getting older, these could also be signs that your testosterone is low. […] You already know that without enough testosterone, fat-burning muscles cant grow, and any excess calories you eat risk being stored as fat. […] If you do put on excess weight, you may find it in an unwanted area: your chest. The technical term for breast growth in men is gynecomastia, and can be related to an increased level of estrogen in comparison to testosterone, says Calvert.

• #67 Male hypogonadism: Symptoms, causes, and treatment

  https://www.medicalnewstoday.com/articles/307634

  Male hypogonadism, also known as testosterone deficiency, describes when the testes are unable to produce the male sex hormone testosterone, sperm, or both. […] The signs and symptoms depend on when it starts, how severe the deficiency is, and whether or not there is a decrease in the major functions of the testes. […] If hypogonadism occurs before puberty, puberty does not progress. If it occurs after puberty, there may be infertility and sexual dysfunction. […] In adult men, symptoms begin within a few weeks of the onset of testosterone deficiency. […] A lack of testosterone can cause a wide range of symptoms. […] Symptoms of adult-onset hypogonadism include: erectile dysfunction, low sperm count, depressed mood, decreased libido, lethargy, sleep disturbances, decreased muscle mass and strength, loss of body hair (pubic, axillary, facial), osteoporosis and decreased bone mineral density, increased body fat, breast discomfort and enlargement, hot flashes, sweating, poor concentration and decreased energy.

• #68 Do I Have Low Testosterone? 13 Symptoms to Look for

  https://honehealth.com/edge/symptoms-of-low-testosterone-in-men/?srsltid=AfmBOop13vO8lVp1hwjMp–wzxCpYz84BUiDUTEga0T9yQJokTLB4BYt

  Losing facial and body hair can also be a symptom of low testosterone in men. […] This isnt just something women experience during menopause. Men, especially those with low T, can get hot flashes, too. […] Its ironic because low testosterone can lead to insomnia and insomnia can lead to low testosterone, Staheli notes. […] Fatigue is a common sign of low testosterone. You might feel like you just dont have the energy that youre used to. Or you might be incredibly tired, all the time. […] Men with low T may be more prone to broken bones and osteoporosis. […] Another way low T can make you feel tired and weak is by causing anemia, a condition in which you lack enough healthy red blood cells to carry adequate oxygen to your organs and tissues. […] When T levels decrease below 300 ng/dL and start causing symptoms, its called hypogonadism.

• #69 Male hypogonadism – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/male-hypogonadism/symptoms-causes/syc-20354881

  Male hypogonadism is a condition in which the body doesn’t produce enough of the hormone that plays a key role in masculine growth and development during puberty (testosterone) or enough sperm or both. […] Hypogonadism can begin during fetal development, before puberty or during adulthood. Signs and symptoms depend on when the condition develops. […] Male hypogonadism can delay puberty or cause incomplete or lack of normal development. It can hamper: Development of muscle mass, Voice deepening, Growth of body and facial hair, Growth of the penis and testicles. […] In adult males, hypogonadism can alter certain masculine physical characteristics and impair normal reproductive function. Early signs and symptoms might include: Decreased sex drive, Decreased energy, Depression. […] Over time, men with hypogonadism can develop: Erectile dysfunction, Infertility, Decrease in hair growth on the face and body, Decrease in muscle mass, Development of breast tissue (gynecomastia), Loss of bone mass (osteoporosis). […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: Difficulty concentrating, Hot flashes.

• #70 Hypogonadism in men – Symptoms, diagnosis and treatment | BMJ Best Practice

  https://bestpractice.bmj.com/topics/en-us/1093

  Other diagnostic factors include decreased energy and fatigue, absent or incomplete puberty, scrotal hypoplasia, hypopigmentation, and absent rugae, decreased muscle mass and strength, loss of axillary and pubic hair, lack of facial hair, poor concentration and memory, depressed or labile mood, sleep disturbance, hot flushes and sweats, tall stature, and fine wrinkling of facial skin.

• #71 Male Hypogonadism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK532933/

  Male hypogonadism, acquired or congenital, can be caused by defects that interfere with the hypothalamic-pituitary-testicular axis. Symptoms highly suggestive of hypogonadism include decreased spontaneous erections, decreased nocturnal penile tumescence, decreased libido, and reduced testicular volume. […] Symptoms highly suggestive of hypogonadism include decreased spontaneous erections, reduced nocturnal penile tumescence, infrequent morning erections, low libido, unexplained fatigue, and smaller testicular volume. […] Symptoms highly suggestive of androgen deficiency in men include reduced sexual desire, decreased spontaneous erections, fatigue, lethargy, loss of axillary and pubic hair, visual field changes (such as bitemporal hemianopsia), loss of smell (anosmia), declining or small testicular volume, hot flashes, and infertility with low or absent sperm counts. Other less suggestive symptoms include depressed mood, irritability, poor concentration, increased body fat, decreased physical performance, lower muscle mass, reduced endurance, weight loss, reduced energy, and loss of appetite.

• #72 Hypogonadism in men – Symptoms, diagnosis and treatment | BMJ Best Practice

  https://bestpractice.bmj.com/topics/en-us/1093

  Hypogonadism in men may present with reproductive/sexual clinical features (e.g., incomplete pubertal development, infertility, gynaecomastia), as well as non-reproductive features (e.g., fatigue, osteoporosis, loss of motivation or concentration, irritability, low or labile mood, body image concerns). […] Patients may have additional symptoms due to mass effects when caused by large parasellar lesions (e.g., headache, peripheral visual disturbance), or may have signs or symptoms of other hormone deficiencies. […] Key diagnostic factors include decreased libido, loss of spontaneous morning erections, erectile dysfunction, gynaecomastia, infertility, micropenis, small testes, bifid or hypoplastic scrotum, cryptorchidism, especially if bilateral, segmental dysproportion, bitemporal hemianopia, low trauma fractures, loss of height, and anosmia.

• #73 Male hypogonadism | Endocrine Conditions

  https://www.yourhormones.info/endocrine-conditions/male-hypogonadism/

  Male hypogonadism is the result of deficiency of the male sex hormone testosterone. It can lead to loss of sex drive and function, delayed puberty, osteoporosis, and there can also be associated failure of the testes to produce sperm. […] Male hypogonadism describes a state of low levels of the male hormone testosterone in men. […] The signs and symptoms depend on the stage at which the patient presents with hypogonadism in relation to sexual maturity. If testosterone deficiency occurs before or during puberty, signs and symptoms are likely to include: […] In men who have already reached sexual maturity, symptoms are likely to include: […] Male hypogonadism is more common in ageing men. The levels of testosterone in men start to fall after the age of 40. […] Symptoms of male hypogonadism, such as lack of sex drive, inadequate erections (erectile dysfunction) and infertility, can lead to low self-esteem and cause depression.

• #74 Male Hypogonadism: Symptoms, Causes, and Treatment Options – The Kingsley Clinic

  https://thekingsleyclinic.com/resources/male-hypogonadism-symptoms-causes-and-treatment-options/

  Male hypogonadism occurs when the testes fail to produce sufficient testosterone, a hormone essential for male growth and development. […] The progression of male hypogonadism varies depending on the underlying cause. In some cases, it develops gradually, while in others, it can occur suddenly. Symptoms often worsen as testosterone levels decline. Common symptoms include fatigue, reduced libido, erectile dysfunction, and loss of muscle mass. […] Decreased libido, or reduced interest in sexual activity, is one of the most common symptoms of male hypogonadism, affecting 70-80% of patients. […] Erectile dysfunction (ED) affects about 50-60% of men with hypogonadism. […] Fatigue is reported in 60-70% of men with hypogonadism. […] Depression occurs in 30-40% of men with hypogonadism. […] Reduced muscle mass is seen in 40-50% of men with hypogonadism.

• #75 Male hypogonadism: Symptoms, causes, and treatment

  https://www.medicalnewstoday.com/articles/307634

  Male hypogonadism, also known as testosterone deficiency, describes when the testes are unable to produce the male sex hormone testosterone, sperm, or both. […] The signs and symptoms depend on when it starts, how severe the deficiency is, and whether or not there is a decrease in the major functions of the testes. […] If hypogonadism occurs before puberty, puberty does not progress. If it occurs after puberty, there may be infertility and sexual dysfunction. […] In adult men, symptoms begin within a few weeks of the onset of testosterone deficiency. […] A lack of testosterone can cause a wide range of symptoms. […] Symptoms of adult-onset hypogonadism include: erectile dysfunction, low sperm count, depressed mood, decreased libido, lethargy, sleep disturbances, decreased muscle mass and strength, loss of body hair (pubic, axillary, facial), osteoporosis and decreased bone mineral density, increased body fat, breast discomfort and enlargement, hot flashes, sweating, poor concentration and decreased energy.

• #76 Male hypogonadism | Health Library | Memorial Health System

  https://www.mhsystem.org/health-library/con-20212413/

  Male hypogonadism is a condition in which the body doesnt produce enough of the hormone that plays a key role in masculine growth and development during puberty (testosterone) or enough sperm or both. […] Hypogonadism can begin during fetal development, before puberty or during adulthood. Signs and symptoms depend on when the condition develops. […] If the body doesnt produce enough testosterone during fetal development, the result may be impaired growth of the external sex organs. […] Male hypogonadism can delay puberty or cause incomplete or lack of normal development. It can hamper: Development of muscle mass, Voice deepening, Growth of body and facial hair, Growth of the penis and testicles. […] In adult males, hypogonadism can alter certain masculine physical characteristics and impair normal reproductive function. Early signs and symptoms might include: Decreased sex drive, Decreased energy, Depression.

• #77 Male hypogonadism – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/male-hypogonadism/symptoms-causes/syc-20354881

  Male hypogonadism is a condition in which the body doesn’t produce enough of the hormone that plays a key role in masculine growth and development during puberty (testosterone) or enough sperm or both. […] Hypogonadism can begin during fetal development, before puberty or during adulthood. Signs and symptoms depend on when the condition develops. […] Male hypogonadism can delay puberty or cause incomplete or lack of normal development. It can hamper: Development of muscle mass, Voice deepening, Growth of body and facial hair, Growth of the penis and testicles. […] In adult males, hypogonadism can alter certain masculine physical characteristics and impair normal reproductive function. Early signs and symptoms might include: Decreased sex drive, Decreased energy, Depression. […] Over time, men with hypogonadism can develop: Erectile dysfunction, Infertility, Decrease in hair growth on the face and body, Decrease in muscle mass, Development of breast tissue (gynecomastia), Loss of bone mass (osteoporosis). […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: Difficulty concentrating, Hot flashes.

• #78 Male hypogonadism | Health Library | Memorial Health System

  https://www.mhsystem.org/health-library/con-20212413/

  Over time, men with hypogonadism can develop: Erectile dysfunction, Infertility, Decrease in hair growth on the face and body, Decrease in muscle mass, Development of breast tissue (gynecomastia), Loss of bone mass (osteoporosis). […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: Difficulty concentrating, Hot flashes. […] The complications of untreated hypogonadism differ depending on when it develops during fetal development, puberty or adulthood. Complications might include: Abnormal genitalia, Enlarged male breasts (gynecomastia), Infertility, Erectile dysfunction, Osteoporosis, Poor self-image. […] Testosterone replacement can raise testosterone levels and help ease the symptoms of male hypogonadism. These include less desire for sex, less energy, less facial and body hair, and loss of muscle mass and bone mass. […] Treatment of delayed puberty in boys depends on the cause. Three to six months of testosterone shots can help start puberty. The testosterone can help increase muscle mass, beard and pubic hair growth, and growth of the penis.

• #79 Low Testosterone (Low T): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/15603-low-testosterone-male-hypogonadism

  The symptoms of low testosterone in adult men include reduced sex drive, erectile dysfunction, fatigue and more. […] Symptoms that highly suggest low testosterone in men include: Reduced sex drive. Erectile dysfunction. Loss of armpit and pubic hair. Shrinking testicles. Hot flashes. Low or zero sperm count (azoospermia), which causes male infertility. […] Other symptoms of low testosterone in men include: Depressed mood. Difficulties with concentration and memory. Increased body fat. Enlarged male breast tissue (gynecomastia). Decrease in muscle strength and mass. Decrease in endurance. […] Late-onset hypogonadism (LOH) is a type of secondary male hypogonadism that results from normal aging. As males age they have a deterioration of hypothalamic-pituitary function and Leydig cell function that decrease testosterone and/or sperm production.

• #80 Understanding the Signs and Symptoms of Low Testosterone Every Man Should Know About – Vale Health Clinic

  https://valehealthclinic.co.uk/understanding-the-signs-and-symptoms-of-low-testosterone-every-man-should-know-about/

  Testosterone levels naturally decline as men age, beginning around 30 to 40. This gradual decline is a part of the normal ageing process. However, this decline can be more severe sometimes, resulting in low testosterone levels that may cause significant health issues. This condition, often called late-onset hypogonadism, can lead to the physical and mental symptoms discussed in the previous section. […] Age-related testosterone deficiency, often late-onset hypogonadism, is a specific subset of low testosterone. Its characterised by a decline in testosterone levels associated with ageing and related symptoms such as fatigue, depression, cognitive decline, reduced sexual desire, and erectile dysfunction. […] The effects of low testosterone can permeate various aspects of a mans life, manifesting in both physical and mental symptoms. By recognising these signs, one can seek help early and prevent potential complications.

• #81 Low Testosterone (Low T): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/15603-low-testosterone-male-hypogonadism

  The symptoms of low testosterone in adult men include reduced sex drive, erectile dysfunction, fatigue and more. […] Symptoms that highly suggest low testosterone in men include: Reduced sex drive. Erectile dysfunction. Loss of armpit and pubic hair. Shrinking testicles. Hot flashes. Low or zero sperm count (azoospermia), which causes male infertility. […] Other symptoms of low testosterone in men include: Depressed mood. Difficulties with concentration and memory. Increased body fat. Enlarged male breast tissue (gynecomastia). Decrease in muscle strength and mass. Decrease in endurance. […] Late-onset hypogonadism (LOH) is a type of secondary male hypogonadism that results from normal aging. As males age they have a deterioration of hypothalamic-pituitary function and Leydig cell function that decrease testosterone and/or sperm production.

• #82 Understanding the Signs and Symptoms of Low Testosterone Every Man Should Know About – Vale Health Clinic

  https://valehealthclinic.co.uk/understanding-the-signs-and-symptoms-of-low-testosterone-every-man-should-know-about/

  Testosterone levels naturally decline as men age, beginning around 30 to 40. This gradual decline is a part of the normal ageing process. However, this decline can be more severe sometimes, resulting in low testosterone levels that may cause significant health issues. This condition, often called late-onset hypogonadism, can lead to the physical and mental symptoms discussed in the previous section. […] Age-related testosterone deficiency, often late-onset hypogonadism, is a specific subset of low testosterone. Its characterised by a decline in testosterone levels associated with ageing and related symptoms such as fatigue, depression, cognitive decline, reduced sexual desire, and erectile dysfunction. […] The effects of low testosterone can permeate various aspects of a mans life, manifesting in both physical and mental symptoms. By recognising these signs, one can seek help early and prevent potential complications.

• #83 Male hypogonadism | Endocrine Conditions

  https://www.yourhormones.info/endocrine-conditions/male-hypogonadism/

  Male hypogonadism is the result of deficiency of the male sex hormone testosterone. It can lead to loss of sex drive and function, delayed puberty, osteoporosis, and there can also be associated failure of the testes to produce sperm. […] Male hypogonadism describes a state of low levels of the male hormone testosterone in men. […] The signs and symptoms depend on the stage at which the patient presents with hypogonadism in relation to sexual maturity. If testosterone deficiency occurs before or during puberty, signs and symptoms are likely to include: […] In men who have already reached sexual maturity, symptoms are likely to include: […] Male hypogonadism is more common in ageing men. The levels of testosterone in men start to fall after the age of 40. […] Symptoms of male hypogonadism, such as lack of sex drive, inadequate erections (erectile dysfunction) and infertility, can lead to low self-esteem and cause depression.

• #84 Male hypogonadism and ageing: rejuvenating the guidance | Society for Endocrinology

  https://www.endocrinology.org/endocrinologist/131-spring19/society-news/male-hypogonadism-and-ageing-rejuvenating-the-guidance/

  Male hypogonadism is a clinical syndrome comprising symptoms and signs AND laboratory evidence of testosterone deficiency. Although the diagnosis conventionally requires sexual symptoms, testosterone is as important for general health in men as it is for sexual health. […] Clinical features can be reproductive (infertility and sexual dysfunction) or non-reproductive (fatigue, reduced physical strength and endurance, loss of motivation or concentration, irritability, low or labile mood, anaemia, and osteoporosis or fracture). […] The absence of a ubiquitous male andropause indicates that men with a well-founded diagnosis of hypogonadism should generally receive testosterone therapy. […] Late-onset hypogonadism (LoH) was originally characterised as a clinical and biochemical syndrome associated with ageing-related co-morbidities (especially obesity), symptoms of testosterone deficiency and consistently low testosterone, after exclusion of classical causes of hypogonadism.

• #85 Could your abnormally low testosterone levels caused by late onset hypogonadism?

  https://www.markvanderpump.co.uk/blog/posts/the-symptoms-diagnosis-and-treatment-of-late-onset-hypogonadism

  As men age their testosterone levels decrease and in middle age this has become known as andropause or – colloquially – the male menopause. At this time men may experience symptoms that are general and non-specific in nature and will probably dismiss them as ageing. However, in some cases they may be suffering from a medical condition called late-onset hypogonadism – this leads to changes in body function which are similar to younger men suffering from hypogonadism. […] These are: Feeling tired and weak, Aching muscles, Loss of body hair, Loss of bone mass (which may increase risk of fractures), Loss of libido, Loss of morning erections, Erectile dysfunction, Difficulty concentrating, Loss of motivation, Irritability, Low moods. […] In 2015 the European Male Aging Study looked at 3369 men aged between 40-79 men and concluded that the condition of late-onset hypogonadism could be ascribed to ageing men presenting with low T (less than 11nmol/L) combined with three symptoms: decreased libido, decreased spontaneous erections and erectile dysfunction. […] Those with severe LOH (less than 8nmol/L) also showed a tendency to insulin resistance and an increased waist circumference.

• #86 Could your abnormally low testosterone levels caused by late onset hypogonadism?

  https://www.markvanderpump.co.uk/blog/posts/the-symptoms-diagnosis-and-treatment-of-late-onset-hypogonadism

  As men age their testosterone levels decrease and in middle age this has become known as andropause or – colloquially – the male menopause. At this time men may experience symptoms that are general and non-specific in nature and will probably dismiss them as ageing. However, in some cases they may be suffering from a medical condition called late-onset hypogonadism – this leads to changes in body function which are similar to younger men suffering from hypogonadism. […] These are: Feeling tired and weak, Aching muscles, Loss of body hair, Loss of bone mass (which may increase risk of fractures), Loss of libido, Loss of morning erections, Erectile dysfunction, Difficulty concentrating, Loss of motivation, Irritability, Low moods. […] In 2015 the European Male Aging Study looked at 3369 men aged between 40-79 men and concluded that the condition of late-onset hypogonadism could be ascribed to ageing men presenting with low T (less than 11nmol/L) combined with three symptoms: decreased libido, decreased spontaneous erections and erectile dysfunction. […] Those with severe LOH (less than 8nmol/L) also showed a tendency to insulin resistance and an increased waist circumference.

• #87 Male hypogonadism | Health Library | Memorial Health System

  https://www.mhsystem.org/health-library/con-20212413/

  Over time, men with hypogonadism can develop: Erectile dysfunction, Infertility, Decrease in hair growth on the face and body, Decrease in muscle mass, Development of breast tissue (gynecomastia), Loss of bone mass (osteoporosis). […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: Difficulty concentrating, Hot flashes. […] The complications of untreated hypogonadism differ depending on when it develops during fetal development, puberty or adulthood. Complications might include: Abnormal genitalia, Enlarged male breasts (gynecomastia), Infertility, Erectile dysfunction, Osteoporosis, Poor self-image. […] Testosterone replacement can raise testosterone levels and help ease the symptoms of male hypogonadism. These include less desire for sex, less energy, less facial and body hair, and loss of muscle mass and bone mass. […] Treatment of delayed puberty in boys depends on the cause. Three to six months of testosterone shots can help start puberty. The testosterone can help increase muscle mass, beard and pubic hair growth, and growth of the penis.

• #88 Male hypogonadism – Hancock Health

  https://www.hancockhealth.org/mayo-health-library/male-hypogonadism/

  Male hypogonadism can delay puberty or cause incomplete or lack of normal development. It can hamper: […] In adult males, hypogonadism can alter certain masculine physical characteristics and impair normal reproductive function. Early signs and symptoms might include: […] Over time, men with hypogonadism can develop: […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: […] The complications of untreated hypogonadism differ depending on when it develops during fetal development, puberty or adulthood. […] Complications might include: […] Early detection in boys can help prevent problems from delayed puberty. Early diagnosis and treatment in men offer better protection against osteoporosis and other related conditions.

• #89 Male Hypogonadism: Causes, Symptoms, and Treatment

  https://www.verywellhealth.com/male-hypogonadism-8651069

  In addition to the common signs and symptoms of hypogonadism, persistently low testosterone levels can lead to longer-term complications like: Muscle atrophy (muscle wasting), Anemia (low numbers of healthy red blood cells), Osteoporosis (porous bones due to bone mineral loss), Increased body fat and central obesity, An increased risk of metabolic syndrome and type 2 diabetes, An increased risk of heart disease due to obesity, type 2 diabetes, and metabolic syndrome. […] Male hypogonadism is diagnosed based on low testosterone blood levels and the appearance of symptoms. […] Testosterone replacement therapy (TRT) is the primary form of treatment for male hypogonadism. TRT is used to normalize testosterone levels with the aim of: Improving libido, sexual function, energy levels, well-being, and moods, Promoting and maintaining secondary male characteristics (virilization), Increasing bone density and preventing osteoporosis, Improving fertility.

• #90 Male hypogonadism // Middlesex Health

  https://middlesexhealth.org/learning-center/diseases-and-conditions/male-hypogonadism

  Male hypogonadism can delay puberty or cause incomplete or lack of normal development. It can hamper: […] In adult males, hypogonadism can alter certain masculine physical characteristics and impair normal reproductive function. Early signs and symptoms might include: […] Over time, men with hypogonadism can develop: […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: […] Testicular failure or pituitary gland dysfunction, affecting testosterone production. […] Testosterone replacement can raise testosterone levels and help ease the symptoms of male hypogonadism. These include less desire for sex, less energy, less facial and body hair, and loss of muscle mass and bone mass.

• #91 Male hypogonadism | Health Library | Memorial Health System

  https://www.mhsystem.org/health-library/con-20212413/

  Over time, men with hypogonadism can develop: Erectile dysfunction, Infertility, Decrease in hair growth on the face and body, Decrease in muscle mass, Development of breast tissue (gynecomastia), Loss of bone mass (osteoporosis). […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: Difficulty concentrating, Hot flashes. […] The complications of untreated hypogonadism differ depending on when it develops during fetal development, puberty or adulthood. Complications might include: Abnormal genitalia, Enlarged male breasts (gynecomastia), Infertility, Erectile dysfunction, Osteoporosis, Poor self-image. […] Testosterone replacement can raise testosterone levels and help ease the symptoms of male hypogonadism. These include less desire for sex, less energy, less facial and body hair, and loss of muscle mass and bone mass. […] Treatment of delayed puberty in boys depends on the cause. Three to six months of testosterone shots can help start puberty. The testosterone can help increase muscle mass, beard and pubic hair growth, and growth of the penis.

• #92 Low Testosterone: Symptoms, causes & treatments | Healthy Male

  https://healthymale.org.au/mens-health/low-testosterone

  Androgen deficiency affects between 1 in 20 and 1 in 200 men. […] If you have androgen deficiency, you might have one or more of these symptoms: Lack energy, Have poor concentration, Feel depressed, Feel weak, Have decreased muscle mass and strength, Put on fat, Feel forgetful, Have trouble sleeping at night or be sleepy during the day, Get erections less often than normal, Have a low sex drive. […] More specific signs of androgen deficiency that your doctor may look for include: Very small testes, A lack of sperm, causing infertility, Impaired sexual maturation, including sparse facial and body hair, A more feminine body fat distribution, Gynaecomastia and soreness of breast tissue can also occur. […] Along with the signs and symptoms listed above, in the long term androgen deficiency increases your chance of developing osteoporosis, which increases your risk of breaking bones. Androgen deficiency also makes you more likely to be diagnosed with a metabolic disease, like diabetes.

• #93 Male Hypogonadism: Causes, Symptoms, and Treatment

  https://www.verywellhealth.com/male-hypogonadism-8651069

  In addition to the common signs and symptoms of hypogonadism, persistently low testosterone levels can lead to longer-term complications like: Muscle atrophy (muscle wasting), Anemia (low numbers of healthy red blood cells), Osteoporosis (porous bones due to bone mineral loss), Increased body fat and central obesity, An increased risk of metabolic syndrome and type 2 diabetes, An increased risk of heart disease due to obesity, type 2 diabetes, and metabolic syndrome. […] Male hypogonadism is diagnosed based on low testosterone blood levels and the appearance of symptoms. […] Testosterone replacement therapy (TRT) is the primary form of treatment for male hypogonadism. TRT is used to normalize testosterone levels with the aim of: Improving libido, sexual function, energy levels, well-being, and moods, Promoting and maintaining secondary male characteristics (virilization), Increasing bone density and preventing osteoporosis, Improving fertility.

• #94 Male Hypogonadism: Causes, Symptoms, and Treatment

  https://www.verywellhealth.com/male-hypogonadism-8651069

  In addition to the common signs and symptoms of hypogonadism, persistently low testosterone levels can lead to longer-term complications like: Muscle atrophy (muscle wasting), Anemia (low numbers of healthy red blood cells), Osteoporosis (porous bones due to bone mineral loss), Increased body fat and central obesity, An increased risk of metabolic syndrome and type 2 diabetes, An increased risk of heart disease due to obesity, type 2 diabetes, and metabolic syndrome. […] Male hypogonadism is diagnosed based on low testosterone blood levels and the appearance of symptoms. […] Testosterone replacement therapy (TRT) is the primary form of treatment for male hypogonadism. TRT is used to normalize testosterone levels with the aim of: Improving libido, sexual function, energy levels, well-being, and moods, Promoting and maintaining secondary male characteristics (virilization), Increasing bone density and preventing osteoporosis, Improving fertility.

• #95 16 signs and symptoms of low testosterone – Centre for Men’s Health

  https://www.centreformenshealth.co.uk/articles/16-signs-and-symptoms-of-low-t

  Low testosterone can show itself in a number of different ways. Low Testosterone symptoms include: […] Of these, fatigue, depression, irritability, reduced sex drive and erection problems are the most common. However, not everybody with the condition will have all of these symptoms and the severity of each will vary from person to person. […] Research has shown that low or ineffective testosterone levels are also implicated in many of the severe, long term illnesses which become common in men with ageing. Metabolic syndrome and diabetes, Alzheimers disease, coronary heart disease and angina, and erectile dysfunction are illnesses where it has been shown testosterone deficiency can both be both part of the cause and be responsible for making the health consequences more severe. […] If you find you are suffering from a number of these low testosterone symptoms at the same time, it is important to have your testosterone levels checked (both total and free testosterone) to understand the underlying cause and to see whether you could benefit from testosterone replacement therapy.

• #96 Male Hypogonadism: Causes, Symptoms, and Treatment

  https://www.verywellhealth.com/male-hypogonadism-8651069

  In addition to the common signs and symptoms of hypogonadism, persistently low testosterone levels can lead to longer-term complications like: Muscle atrophy (muscle wasting), Anemia (low numbers of healthy red blood cells), Osteoporosis (porous bones due to bone mineral loss), Increased body fat and central obesity, An increased risk of metabolic syndrome and type 2 diabetes, An increased risk of heart disease due to obesity, type 2 diabetes, and metabolic syndrome. […] Male hypogonadism is diagnosed based on low testosterone blood levels and the appearance of symptoms. […] Testosterone replacement therapy (TRT) is the primary form of treatment for male hypogonadism. TRT is used to normalize testosterone levels with the aim of: Improving libido, sexual function, energy levels, well-being, and moods, Promoting and maintaining secondary male characteristics (virilization), Increasing bone density and preventing osteoporosis, Improving fertility.

• #97 16 signs and symptoms of low testosterone – Centre for Men’s Health

  https://www.centreformenshealth.co.uk/articles/16-signs-and-symptoms-of-low-t

  Low testosterone can show itself in a number of different ways. Low Testosterone symptoms include: […] Of these, fatigue, depression, irritability, reduced sex drive and erection problems are the most common. However, not everybody with the condition will have all of these symptoms and the severity of each will vary from person to person. […] Research has shown that low or ineffective testosterone levels are also implicated in many of the severe, long term illnesses which become common in men with ageing. Metabolic syndrome and diabetes, Alzheimers disease, coronary heart disease and angina, and erectile dysfunction are illnesses where it has been shown testosterone deficiency can both be both part of the cause and be responsible for making the health consequences more severe. […] If you find you are suffering from a number of these low testosterone symptoms at the same time, it is important to have your testosterone levels checked (both total and free testosterone) to understand the underlying cause and to see whether you could benefit from testosterone replacement therapy.

• #98 Testosterone Deficiency, Hypogonadism

  https://www.froedtert.com/mens-reproductive-sexual-health/testosterone-deficiency

  Male hypogonadism is a deficiency of testosterone in men. About 5 percent to 6 percent of men experience low testosterone, and the condition becomes more common as a man ages. […] Symptoms include low sperm count, decreased libido, erectile dysfunction, fatigue, sleep disturbances and depression. […] For men with primary hypogonadism, treatment typically involves lifelong testosterone replacement therapy. […] Secondary hypogonadism is treated by addressing the root cause – a disorder with the hypothalamus or pituitary gland. […] Infertility related to secondary hypogonadism may respond to hormonal replacement therapy. Infertility related to primary hypogonadism, however, does not respond to hormonal therapy.

• #99 Male Hypogonadism: Causes, Symptoms, and Treatment

  https://www.verywellhealth.com/male-hypogonadism-8651069

  Psychological symptoms of male hypogonadism include: Depression, Difficulty concentration, Forgetfulness, Mental fogginess. […] Sexual symptoms of male hypogonadism include: Erectile dysfunction (ED), Infertility, Low libido. […] Signs of hypogonadism at birth are exceptionally rare, affecting 1 of every 5,000 to 10,000 newborn males. Most cases are only recognized during puberty when the lack of testosterone affects sexual and physical development, resulting in delayed puberty. […] If left untreated, puberty-onset hypogonadism may lead to permanent short stature, microorchidism (small testicles), and impaired fertility in some males. […] Adult-onset hypogonadism, also known as late-onset hypogonadism, is an abnormal drop in testosterone beyond what would be expected for your age, coupled with the onset of hypogonadal symptoms.

• #100 Male Hypogonadism: Causes, Symptoms, and Treatment

  https://www.verywellhealth.com/male-hypogonadism-8651069

  Psychological symptoms of male hypogonadism include: Depression, Difficulty concentration, Forgetfulness, Mental fogginess. […] Sexual symptoms of male hypogonadism include: Erectile dysfunction (ED), Infertility, Low libido. […] Signs of hypogonadism at birth are exceptionally rare, affecting 1 of every 5,000 to 10,000 newborn males. Most cases are only recognized during puberty when the lack of testosterone affects sexual and physical development, resulting in delayed puberty. […] If left untreated, puberty-onset hypogonadism may lead to permanent short stature, microorchidism (small testicles), and impaired fertility in some males. […] Adult-onset hypogonadism, also known as late-onset hypogonadism, is an abnormal drop in testosterone beyond what would be expected for your age, coupled with the onset of hypogonadal symptoms.

• #101 Male hypogonadism | Endocrine Conditions

  https://www.yourhormones.info/endocrine-conditions/male-hypogonadism/

  Male hypogonadism is the result of deficiency of the male sex hormone testosterone. It can lead to loss of sex drive and function, delayed puberty, osteoporosis, and there can also be associated failure of the testes to produce sperm. […] Male hypogonadism describes a state of low levels of the male hormone testosterone in men. […] The signs and symptoms depend on the stage at which the patient presents with hypogonadism in relation to sexual maturity. If testosterone deficiency occurs before or during puberty, signs and symptoms are likely to include: […] In men who have already reached sexual maturity, symptoms are likely to include: […] Male hypogonadism is more common in ageing men. The levels of testosterone in men start to fall after the age of 40. […] Symptoms of male hypogonadism, such as lack of sex drive, inadequate erections (erectile dysfunction) and infertility, can lead to low self-esteem and cause depression.

• #102 Testosterone Deficiency / Low (Hypogonadism): Causes, Symptoms, Diagnosis and Treatment

  https://dreminozbek.com/en/testosterone-deficiency-low-hypogonadism-causes-symptoms-diagnosis-and-treatment/

  Adult age: Decreased sexual desire, A general lack of energy, Depression and general mood disorder, Erection problems, Infertility problems, Reduction in muscle mass, Reduction in hair beard and general hair distribution, Osteoporosis (weakening of bones), Mental and emotional problems, Lack of concentration in daily work, Hot flashes. […] T deficiency in men can lead to some serious problems if left untreated. Common problems (complications) related to low T are as follows; Insufficient development of male genital organs, Gynecomastia (breast enlargement in men), Infertility (infertility), Sexual dysfunctions (erectile dysfunction, impotence), Weakening in bones (osteoporosis, osteoporosis), Person not feeling well, Concentration problem, Mental problems, Problems in social life, Problems in professional life, Familial problems.

• #103 Male hypogonadism | Health Library | Memorial Health System

  https://www.mhsystem.org/health-library/con-20212413/

  Over time, men with hypogonadism can develop: Erectile dysfunction, Infertility, Decrease in hair growth on the face and body, Decrease in muscle mass, Development of breast tissue (gynecomastia), Loss of bone mass (osteoporosis). […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: Difficulty concentrating, Hot flashes. […] The complications of untreated hypogonadism differ depending on when it develops during fetal development, puberty or adulthood. Complications might include: Abnormal genitalia, Enlarged male breasts (gynecomastia), Infertility, Erectile dysfunction, Osteoporosis, Poor self-image. […] Testosterone replacement can raise testosterone levels and help ease the symptoms of male hypogonadism. These include less desire for sex, less energy, less facial and body hair, and loss of muscle mass and bone mass. […] Treatment of delayed puberty in boys depends on the cause. Three to six months of testosterone shots can help start puberty. The testosterone can help increase muscle mass, beard and pubic hair growth, and growth of the penis.

• #104 Male hypogonadism | Endocrine Conditions

  https://www.yourhormones.info/endocrine-conditions/male-hypogonadism/

  Male hypogonadism is the result of deficiency of the male sex hormone testosterone. It can lead to loss of sex drive and function, delayed puberty, osteoporosis, and there can also be associated failure of the testes to produce sperm. […] Male hypogonadism describes a state of low levels of the male hormone testosterone in men. […] The signs and symptoms depend on the stage at which the patient presents with hypogonadism in relation to sexual maturity. If testosterone deficiency occurs before or during puberty, signs and symptoms are likely to include: […] In men who have already reached sexual maturity, symptoms are likely to include: […] Male hypogonadism is more common in ageing men. The levels of testosterone in men start to fall after the age of 40. […] Symptoms of male hypogonadism, such as lack of sex drive, inadequate erections (erectile dysfunction) and infertility, can lead to low self-esteem and cause depression.

• #105 Low testosterone guide: Symptoms, causes, diagnosis, testosterone tests, and treatment

  https://www.trted.org/articles/hypogonadism-low-testosterone-the-complete-guide

  Hypogonadism is a condition where clinically low testosterone levels have been diagnosed, along with symptoms associated with the deficiency. […] Symptoms include low sex drive, erectile dysfunction, fatigue, and depression. […] Hypogonadism is linked to various conditions, including type 2 diabetes, cardiovascular disease, and obesity. It often presents itself through symptoms like low sex drive (low libido), erectile dysfunction, feelings of depression, and irritability. […] Additionally, it’s associated with anemia, reduced muscle mass, and decreased bone density, which can result in overall weakness, limited mobility, and an elevated risk of falls and fractures. […] Hypogonadism can also cause strain on relationships with partners, particularly when undiagnosed and neither part of the couple understands the underlying cause for these changes. Therefore, it is crucial that hypogonadal men are diagnosed and treated appropriately to ensure their continued quality of life into older age. […] Starting around the age of 40, testosterone levels typically begin to decline gradually. In certain cases, these levels can drop to clinically low points, resulting in a range of symptoms that can significantly impact a man’s overall quality of life.

• #106 Testosterone Deficiency / Low (Hypogonadism): Causes, Symptoms, Diagnosis and Treatment

  https://dreminozbek.com/en/testosterone-deficiency-low-hypogonadism-causes-symptoms-diagnosis-and-treatment/

  Adult age: Decreased sexual desire, A general lack of energy, Depression and general mood disorder, Erection problems, Infertility problems, Reduction in muscle mass, Reduction in hair beard and general hair distribution, Osteoporosis (weakening of bones), Mental and emotional problems, Lack of concentration in daily work, Hot flashes. […] T deficiency in men can lead to some serious problems if left untreated. Common problems (complications) related to low T are as follows; Insufficient development of male genital organs, Gynecomastia (breast enlargement in men), Infertility (infertility), Sexual dysfunctions (erectile dysfunction, impotence), Weakening in bones (osteoporosis, osteoporosis), Person not feeling well, Concentration problem, Mental problems, Problems in social life, Problems in professional life, Familial problems.

• #107 Testosterone Deficiency / Low (Hypogonadism): Causes, Symptoms, Diagnosis and Treatment

  https://dreminozbek.com/en/testosterone-deficiency-low-hypogonadism-causes-symptoms-diagnosis-and-treatment/

  Adult age: Decreased sexual desire, A general lack of energy, Depression and general mood disorder, Erection problems, Infertility problems, Reduction in muscle mass, Reduction in hair beard and general hair distribution, Osteoporosis (weakening of bones), Mental and emotional problems, Lack of concentration in daily work, Hot flashes. […] T deficiency in men can lead to some serious problems if left untreated. Common problems (complications) related to low T are as follows; Insufficient development of male genital organs, Gynecomastia (breast enlargement in men), Infertility (infertility), Sexual dysfunctions (erectile dysfunction, impotence), Weakening in bones (osteoporosis, osteoporosis), Person not feeling well, Concentration problem, Mental problems, Problems in social life, Problems in professional life, Familial problems.

• #108 Low Testosterone (Low T): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/15603-low-testosterone-male-hypogonadism

  The mortality of men with testosterone deficiency is significantly higher than among men with normal testosterone levels. But, it is unclear whether replacing testosterone to a normal level reduces that increased mortality. Treatment is largely focused on the treatment of symptoms, not the specific testosterone level.

• #109 Male hypogonadism – Hancock Health

  https://www.hancockhealth.org/mayo-health-library/male-hypogonadism/

  Male hypogonadism can delay puberty or cause incomplete or lack of normal development. It can hamper: […] In adult males, hypogonadism can alter certain masculine physical characteristics and impair normal reproductive function. Early signs and symptoms might include: […] Over time, men with hypogonadism can develop: […] Severe hypogonadism can also cause mental and emotional changes. As testosterone decreases, some men have symptoms similar to those of menopause in women. These can include: […] The complications of untreated hypogonadism differ depending on when it develops during fetal development, puberty or adulthood. […] Complications might include: […] Early detection in boys can help prevent problems from delayed puberty. Early diagnosis and treatment in men offer better protection against osteoporosis and other related conditions.

• #110 Male hypogonadism – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/male-hypogonadism/diagnosis-treatment/drc-20354886

  Testosterone replacement can raise testosterone levels and help ease the symptoms of male hypogonadism. These include less desire for sex, less energy, less facial and body hair, and loss of muscle mass and bone mass. […] Treatment of delayed puberty in boys depends on the cause. Three to six months of testosterone shots can help start puberty. The testosterone can help increase muscle mass, beard and pubic hair growth, and growth of the penis. This treatment is given only if the bones have matured enough.

• #111 Male hypogonadism: Symptoms, causes, and treatment

  https://www.medicalnewstoday.com/articles/307634

  Hypogonadism in a male refers to a decrease in either or both of the two major functions of the testes: sperm production and testosterone production. […] Testosterone replacement therapy (TRT) is the recommended treatment for male hypogonadism. […] TRT can eliminate many, if not all, of the signs and symptoms of male hypogonadism. […] Awareness of male hypogonadism is growing, but many adult men with the condition remain undiagnosed and untreated. […] Any male who thinks he may have low testosterone levels should seek medical advice, as treatment can reverse most of the symptoms and risks of male hypogonadism.

• #112 Male Hypogonadism: Causes, Symptoms, and Treatment

  https://www.verywellhealth.com/male-hypogonadism-8651069

  In addition to the common signs and symptoms of hypogonadism, persistently low testosterone levels can lead to longer-term complications like: Muscle atrophy (muscle wasting), Anemia (low numbers of healthy red blood cells), Osteoporosis (porous bones due to bone mineral loss), Increased body fat and central obesity, An increased risk of metabolic syndrome and type 2 diabetes, An increased risk of heart disease due to obesity, type 2 diabetes, and metabolic syndrome. […] Male hypogonadism is diagnosed based on low testosterone blood levels and the appearance of symptoms. […] Testosterone replacement therapy (TRT) is the primary form of treatment for male hypogonadism. TRT is used to normalize testosterone levels with the aim of: Improving libido, sexual function, energy levels, well-being, and moods, Promoting and maintaining secondary male characteristics (virilization), Increasing bone density and preventing osteoporosis, Improving fertility.

• #113 Prevalence, Diagnosis and Treatment of Hypogonadism in Primary Care Practice » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/publications/prevalence-diagnosis-and-treatment-of-hypogonadism-in-primary-care-practice/

  A younger patient may have pure hypogonadism as a primary event, whereas an older man may have an age-related decline in testosterone production that is a part of his ED profile. […] Treatments to normalize testosterone can not only improve libido, energy level and the potential to have normal erections, but can also improve the response to sildenafil, if that is deemed appropriate treatment. […] The goal of testosterone replacement therapy is to provide and maintain a normal level of testosterone, thereby restoring libido and improving erectile function; improving mood and providing a sense of well-being; decreasing fatigue; and improving lean body mass, strength and stamina. […] Testosterone replacement therapy can return hormone levels to normal ranges and help alleviate the symptoms associated with hypogonadism.

• #114 Male hypogonadism – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/male-hypogonadism/diagnosis-treatment/drc-20354886

  Testosterone replacement can raise testosterone levels and help ease the symptoms of male hypogonadism. These include less desire for sex, less energy, less facial and body hair, and loss of muscle mass and bone mass. […] Treatment of delayed puberty in boys depends on the cause. Three to six months of testosterone shots can help start puberty. The testosterone can help increase muscle mass, beard and pubic hair growth, and growth of the penis. This treatment is given only if the bones have matured enough.

• #115 Male hypogonadism // Middlesex Health

  https://middlesexhealth.org/learning-center/diseases-and-conditions/male-hypogonadism

  If a pituitary problem is the cause, pituitary hormones can be given to help the body make more sperm and restore fertility. […] Treatment of delayed puberty in boys depends on the cause. Three to six months of testosterone shots can help start puberty. The testosterone can help increase muscle mass, beard and pubic hair growth, and growth of the penis. This treatment is given only if the bones have matured enough.

• #116 Male hypogonadism // Middlesex Health

  https://middlesexhealth.org/learning-center/diseases-and-conditions/male-hypogonadism

  If a pituitary problem is the cause, pituitary hormones can be given to help the body make more sperm and restore fertility. […] Treatment of delayed puberty in boys depends on the cause. Three to six months of testosterone shots can help start puberty. The testosterone can help increase muscle mass, beard and pubic hair growth, and growth of the penis. This treatment is given only if the bones have matured enough.

• #117 Testosterone Deficiency, Hypogonadism

  https://www.froedtert.com/mens-reproductive-sexual-health/testosterone-deficiency

  Male hypogonadism is a deficiency of testosterone in men. About 5 percent to 6 percent of men experience low testosterone, and the condition becomes more common as a man ages. […] Symptoms include low sperm count, decreased libido, erectile dysfunction, fatigue, sleep disturbances and depression. […] For men with primary hypogonadism, treatment typically involves lifelong testosterone replacement therapy. […] Secondary hypogonadism is treated by addressing the root cause – a disorder with the hypothalamus or pituitary gland. […] Infertility related to secondary hypogonadism may respond to hormonal replacement therapy. Infertility related to primary hypogonadism, however, does not respond to hormonal therapy.

• #118 Male Hypogonadism | AMBOSS Rotation Prep

  https://resident360.amboss.com/adult-medicine/endocrinology/male-hypogonadism/male-hypogonadism.html

  Male hypogonadism refers to a decrease in one or both major functions of the testes sperm production and testosterone production. […] In male hypogonadism, the body does not produce enough testosterone or sperm. […] Clinical signs and symptoms of hypogonadism are nonspecific and include: decreased libido, decreased spontaneous erections, fatigue, hot flashes, depressed mood, difficulty with concentration, decreased muscle mass. […] In patients with confirmed hypogonadism, testosterone replacement therapy can be initiated to maintain secondary sexual characteristics, sexual function, and quality of life. […] Testosterone therapy inhibits spermatogenesis. This should be considered in men with low testosterone who are interested in starting a family in the near future.

• #119 Male hypogonadism and ageing: rejuvenating the guidance | Society for Endocrinology

  https://www.endocrinology.org/endocrinologist/131-spring19/society-news/male-hypogonadism-and-ageing-rejuvenating-the-guidance/

  Testosterone treatment should be avoided in men who are actively seeking biological parenthood. […] Therefore, whereas testosterone replacement has been used for many years, effectively and without major adverse effects, in men of all ages with classical hypogonadism, this experience and the risk-benefit balance cannot be extrapolated to older men whose low testosterone levels predominantly reflect frailty or other NGI. […] Occult prostate cancer is common in elderly men and, in the absence of long term studies, it is unclear whether testosterone therapy can promote tumour growth. […] The long term effects of testosterone treatment on cardiovascular disease susceptibility are currently unknown and it should therefore be used cautiously in men with symptomatic cardiovascular disease.

• #120 Male hypogonadism – Hancock Health

  https://www.hancockhealth.org/mayo-health-library/male-hypogonadism/

  Testosterone replacement can raise testosterone levels and help ease the symptoms of male hypogonadism. These include less desire for sex, less energy, less facial and body hair, and loss of muscle mass and bone mass. […] For older adults who have low testosterone and symptoms of hypogonadism due to aging, it’s less clear how well testosterone replacement works. […] Testosterone therapy carries risks, including: […] Risks from testosterone therapy are most often due to doses that are too high. Many of these side effects go away when the dose is lowered. That’s why it’s so important to have regular follow-up visits with a health care professional, who will monitor the testosterone levels in your blood. […] Treatment of delayed puberty in boys depends on the cause. Three to six months of testosterone shots can help start puberty. The testosterone can help increase muscle mass, beard and pubic hair growth, and growth of the penis. This treatment is given only if the bones have matured enough.

• #121 Hypogonadism (Low Testosterone) | UCSF Department of Urology

  https://urology.ucsf.edu/patient-care/adult-non-cancer/male-sexual-and-reproductive-health/hypogonadism

  Many men with low blood levels of testosterone are completely asymptomatic; however, men with low T are more likely than other men to report changes in sex drive or erections, fatigue, loss of muscle mass, irritability, poor sleep, and infertility. […] It is important to note that the symptoms associated with low testosterone are very general; in others, low testosterone may not be the root cause of a given man’s symptoms, even if he also has a low blood level of testosterone. Not all men with low testosterone and symptoms will benefit from testosterone supplementation. If a man taking testosterone has normalization of his blood levels but still does not experience clinical improvements within three months he may need to consider alternative causes or treatments for his symptoms.

• #122 Could you have low testosterone?: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/patientinstructions/000722.htm

  Testosterone is a hormone made by the testicles. It is important for a man’s sex drive and physical appearance. […] Low testosterone can affect sex drive, mood, and changes in muscle and fat. […] Some men with low testosterone do not have any symptoms. Others may have: Low sex drive, Problems having an erection, Low sperm count, Sleep problems such as insomnia, Decrease in muscle size and strength, Bone loss, Increase in body fat, Depression, Trouble concentrating. […] Symptoms may also be caused by other conditions, such as high blood pressure or diabetes. If any of these symptoms are bothering you, talk with your provider. […] If you have low testosterone, hormone therapy may help. […] TRT may relieve or improve symptoms in some men. It may help keep bones and muscles strong. […] Talk with your provider about whether TRT is right for you. If you do not notice any change in symptoms after treatment for 3 months, it is less likely that TRT treatment will benefit you. […] Contact your provider if: You have symptoms of low testosterone.

• #123 Male Hypogonadism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK532933/

  Decreased muscle mass and body hair changes typically take years to manifest. Infertility, gynecomastia, and decreased testicular size are more typical of primary rather than secondary hypogonadism. […] The prognosis is excellent for symptomatic men diagnosed with male hypogonadism who are treated according to guidelines and followed appropriately. While the condition is not usually curable, it is amenable to treatment with clomiphene or testosterone replacement therapy. Optimal results are obtained when proper follow-up is implemented and treatment is modified appropriately to utilize the minimal acceptable dose to relieve symptoms and avoid side effects.

• #124 Male Hypogonadism: Causes, Symptoms, and Treatment

  https://www.verywellhealth.com/male-hypogonadism-8651069

  Depending on the underlying cause, male hypogonadism can sometimes be cured. In other cases, low T may require lifelong management. […] Male hypogonadism is abnormally low testosterone levels in males. Symptoms include fatigue, lack of concentration, low energy, muscle weakness, irritability, depression, low sex drive, erectile dysfunction, and infertility. Hypogonadism in male children can lead to delayed puberty and stunted growth.

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