Materiały źródłowe

• #1 A noninvasive treatment for “chemo brain” | Picower Institute

  https://picower.mit.edu/news/noninvasive-treatment-chemo-brain

  Stimulating gamma brain waves may protect cancer patients from memory impairment and other cognitive effects of chemotherapy. […] Patients undergoing chemotherapy often experience cognitive effects such as memory impairment and difficulty concentrating a condition commonly known as chemo brain. […] The treatment also helped to prevent memory loss and impairment of other cognitive functions. […] We know that this gamma sensory stimulation has anti-inflammatory effects, so we decided to use the chemo brain model to test whether sensory gamma stimulation can be beneficial. […] However, mice that received gamma therapy along with cisplatin treatment showed significant reductions in all of those symptoms. […] The gamma therapy also had beneficial effects on behavior: Mice that received the therapy performed much better on tests designed to measure memory and executive function.

• #2 Study finds chemo brain persists after treatment in patients

  https://www.cancercenter.com/community/blog/2017/02/study-finds-chemo-brain-persists-after-treatment-in-breast-cancer-patients

  Chemo brain symptoms include lapses in short-term memory, difficulty remembering names and dates and problems concentrating. […] Many cancer patients who undergo chemotherapy begin treatment expecting to deal with two of its most dreaded side effects: fatigue and hair loss. But theres something else they should be prepared to address that may be just as disruptive: cognitive impairment that makes it difficult to concentrate and perform everyday tasks. […] Commonly called chemo brain, its often described as an overall mental fogginess, and breast cancer patients may find that it lasts for six months after chemotherapy ends, according to a study published in the December 2016 Journal of Clinical Oncology. […] Additional research has found that other cancer treatments—surgery, radiation and hormone therapy among them—also may lead to chemo brain, because they cause inflammation in the body.

• #3 Cognitive behavioral therapy may help ease 'chemo brain’ – The Washington Post

  https://www.washingtonpost.com/wellness/2023/06/18/chemo-brain-treatment/

  By the time she finished her second round of chemotherapy for breast cancer, Shannon Colleary says her brain felt foggy. […] What both Colleary and Schuster describe is often called “chemo brain,” shorthand for a debilitating medical condition characterized by loss of word retrieval, memory and executive function, and an inability to concentrate. Physicians call it cancer-related cognitive impairment (CRCI), and research indicates it affects about 75 percent of cancer patients during treatment, with 35 percent reporting persistent symptoms after treatment ends. […] But Arum Kim, director of the Supportive Oncology Program at NYU Langone’s Perlmutter Cancer Center, urges people to communicate with their medical team about cognitive changes. […] “Really good, calm communication with your treating oncology team is important because there are things that we can do for it — if we know about it,” she says.

• #4 Brain Fog In Survivors Of Cancer | Franciscan Health

  https://www.franciscanhealth.org/community/blog/brain-fog-cancer-survivors

  Brain fog is a common term used by many patients with cancer and survivors of cancer to describe the cognitive challenges they face during and after treatment. […] Studies suggest that up to 75 percent of cancer patients experience some form of cognitive dysfunction during treatment, and around 35 percent continue to have issues long after treatment ends. […] Speech and occupational therapists can help prevent, assess, diagnose and treat symptoms. […] For some, symptoms of brain fog may resolve fairly quickly with the help of an occupational or speech therapist, but they can also last a lot longer, even years, Hughes said. […] Symptoms may resolve fairly quickly if a patient uses therapy to help address their symptoms, Hughes mentioned. […] While physicians do not have a single treatment for brain fog, several strategies can help manage the symptoms. Occupational therapy and speech therapy play a crucial role. […] Cognitive Behavioral Therapy (CBT) can help patients develop strategies to cope with cognitive changes. […] Many survivors of cancer report that brain fog improves over time, especially with appropriate treatment and support.

• #5 Fat Molecule in Brain Linked to Chemo Brain – NCI

  https://www.cancer.gov/news-events/cancer-currents-blog/2022/chemo-brain-prevention-s1p

  A significant number of patients who undergo cisplatin treatment are affected by persistent cognitive impairment. […] So, if we can find something that can prevent it, it would really be groundbreaking. […] She said the team will next investigate whether these multiple sclerosis drugs could not just prevent chemo brain symptoms from developing, but also reverse symptoms of cognitive impairment once they have developed. […] More research needs to be done before these drugs could be used to prevent chemotherapy-related cognitive issues in people, Dr. Salvemini stressed. […] We want to look at not only if can we prevent cognitive impairment [in people with cancer], but if we can treat and improve it, she said. […] [The improvement] may not be 100%, but even if we can improve it by 20% or 30% that could have a major impact on somebody’s life.

• #6 Chemo Brain | HealthLink BC

  https://www.healthlinkbc.ca/healthwise/chemo-brain

  Chemo brain is a problem with thinking and memory that can happen during and especially after chemotherapy treatment for cancer. […] Research is ongoing to learn more about how chemo brain occurs and how to prevent and treat it. […] Studies are being done to see which cancer medicines might be less likely to cause these problems. […] If you still have chemo brain a year after cancer treatment ends, your doctor may suggest that you see a neuropsychologist. These experts help people who have cognitive problems. […] Here are some ideas that may help you cope with this problem. […] Try to relax to reduce your stress. Meditate, or do yoga or another relaxing activity. […] Get plenty of sleep. […] Eat a healthy diet. […] Be as physically active as you can. But check with your doctor to make sure that you don’t do too much too soon.

• #7 A noninvasive treatment for “chemo brain” – ecancer

  https://ecancer.org/en/news/24368-a-noninvasive-treatment-for-chemo-brain

  A noninvasive treatment for chemo brain […] Patients undergoing chemotherapy often experience cognitive effects such as memory impairment and difficulty concentrating a condition commonly known as chemo brain. […] MIT researchers have now shown that a noninvasive treatment that stimulates gamma frequency brain waves may hold promise for treating chemo brain. […] The treatment also helped to prevent memory loss and impairment of other cognitive functions. […] Research has shown that these drugs can induce inflammation in the brain, as well as other detrimental effects such as loss of white matter the networks of nerve fibres that help different parts of the brain communicate with each other. […] Chemo brain caught our attention because it is extremely common, and there is quite a lot of research on what the brain is like following chemotherapy treatment, Tsai says.

• #8 A noninvasive treatment for “chemo brain” | Picower Institute

  https://picower.mit.edu/news/noninvasive-treatment-chemo-brain

  Stimulating gamma brain waves may protect cancer patients from memory impairment and other cognitive effects of chemotherapy. […] Patients undergoing chemotherapy often experience cognitive effects such as memory impairment and difficulty concentrating a condition commonly known as chemo brain. […] The treatment also helped to prevent memory loss and impairment of other cognitive functions. […] We know that this gamma sensory stimulation has anti-inflammatory effects, so we decided to use the chemo brain model to test whether sensory gamma stimulation can be beneficial. […] However, mice that received gamma therapy along with cisplatin treatment showed significant reductions in all of those symptoms. […] The gamma therapy also had beneficial effects on behavior: Mice that received the therapy performed much better on tests designed to measure memory and executive function.

• #9 Study finds chemo brain persists after treatment in patients

  https://www.cancercenter.com/community/blog/2017/02/study-finds-chemo-brain-persists-after-treatment-in-breast-cancer-patients

  We do know that exercise and meditation and eating healthy help produce immune traits (cytokine profile) opposite of those seen in patients exhibiting chemo brain symptoms, says Dr. Ahn. I advise my patients to embrace those lifestyle changes for many more proven reasons such as reduced future cancer risk, with the added benefit that it might help hasten recovery from chemo brain.

• #10 A noninvasive treatment for “chemo brain” – ecancer

  https://ecancer.org/en/news/24368-a-noninvasive-treatment-for-chemo-brain

  A noninvasive treatment for chemo brain […] Patients undergoing chemotherapy often experience cognitive effects such as memory impairment and difficulty concentrating a condition commonly known as chemo brain. […] MIT researchers have now shown that a noninvasive treatment that stimulates gamma frequency brain waves may hold promise for treating chemo brain. […] The treatment also helped to prevent memory loss and impairment of other cognitive functions. […] Research has shown that these drugs can induce inflammation in the brain, as well as other detrimental effects such as loss of white matter the networks of nerve fibres that help different parts of the brain communicate with each other. […] Chemo brain caught our attention because it is extremely common, and there is quite a lot of research on what the brain is like following chemotherapy treatment, Tsai says.

• #11 A noninvasive treatment for “chemo brain” | Picower Institute

  https://picower.mit.edu/news/noninvasive-treatment-chemo-brain

  In mice that received gamma treatment along with cisplatin, some of the beneficial effects could still be seen up to four months later. […] The researchers also showed that the gamma treatment improved the signs of chemo brain in mice that received a different chemotherapy drug, methotrexate, which is used to treat breast, lung, and other types of cancer. […] It seems that its not specific to the agent that induces demyelination, be it chemotherapy or another source of demyelination, Tsai says.

• #12 Chemobrain in Cancer Treatment: Mechanisms and Its Prevention | SpringerLink

  https://link.springer.com/10.1007/978-3-030-80962-1_352-1

  Therapeutic use of chemotherapy has led to a significant increase in the number of cancer survivors worldwide. […] Understanding the mechanisms underlying the development of chemobrain would assist the prevention or treatment of the adverse effects of chemotherapy on brain function. […] In addition to considering biological pathways, we also summarize promising therapeutic strategies to alleviate symptoms of chemobrain which have already been proven to provide effective neuroprotection in chemobrain models. […] Physical exercise prevents cognitive impairment by enhancing hippocampal neuroplasticity and mitochondrial function in doxorubicin-induced chemobrain. […] Donepezil protects against doxorubicin-induced Chemobrain in rats via attenuation of inflammation and oxidative stress without interfering with doxorubicin efficacy.

• #13 Suffering from

  https://www.health.harvard.edu/blog/suffering-from-chemo-brain-theres-hope-and-many-things-you-can-do-2019112018403

  Some of the most common symptoms experienced by cancer patients are memory problems, difficulties with multitasking, and reduced attention and concentration. […] Research over the past decade has revealed that many cancer patients experience such symptoms as a consequence of specific damage to the brain caused by either their tumor or their treatment. […] While various therapeutic interventions currently remain in clinical testing, there are a number of lifestyle actions that have been found to be effective. […] Regular physical exercise. Cardiovascular exercise is one of the strongest drivers of brain repair after injury, stimulating the growth of new neurons, facilitating connections between brain cells, and enhancing overall cognitive resilience. […] Sufficient restorative sleep. Chronic sleep deprivation damages brain cells, prevents brain regeneration, causes daytime fatigue, and reduces cognitive function.

• #14 A Potential Therapy for “Chemobrain” | Columbia University Irving Medical Center

  https://www.cuimc.columbia.edu/news/potential-therapy-chemobrain

  Preventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a cancer chemotherapy. Mice are protected from „chemobrain” when the RY34 domain (pink) is positioned as above, which prevents the leak. […] The team tested the idea in mice and found that a chemotherapy treatment causes calcium leaks in the brain and neurocognitive dysfunction in mice with breast cancer and in healthy mice. The leaked calcium inside cells, the team found, impairs neuronal function. […] The good news is that an experimental drug under development in the Marks lab was able to reduce both the calcium leak in the brain and neurocognitive symptoms in mice. […] Marks and his team hope that a clinical trial is soon-to-come, as there is currently no treatment for this common and distressing impairment.

• #15 Fat Molecule in Brain Linked to Chemo Brain – NCI

  https://www.cancer.gov/news-events/cancer-currents-blog/2022/chemo-brain-prevention-s1p

  A significant number of patients who undergo cisplatin treatment are affected by persistent cognitive impairment. […] So, if we can find something that can prevent it, it would really be groundbreaking. […] She said the team will next investigate whether these multiple sclerosis drugs could not just prevent chemo brain symptoms from developing, but also reverse symptoms of cognitive impairment once they have developed. […] More research needs to be done before these drugs could be used to prevent chemotherapy-related cognitive issues in people, Dr. Salvemini stressed. […] We want to look at not only if can we prevent cognitive impairment [in people with cancer], but if we can treat and improve it, she said. […] [The improvement] may not be 100%, but even if we can improve it by 20% or 30% that could have a major impact on somebody’s life.

• #16

• #17 Cognitive behavioral therapy may help ease 'chemo brain’ – The Washington Post

  https://www.washingtonpost.com/wellness/2023/06/18/chemo-brain-treatment/

  No Food and Drug Administration-approved medications are available for chemo brain, although Mandelblatt predicts it won’t be long before physicians can offer pharmaceutical solutions to their patients. […] “We are making some progress, and I expect that already approved drugs will be repurposed for chemo brain,” says Mandelblatt, noting that studies in mice show promise.

• #18 Fat Molecule in Brain Linked to Chemo Brain – NCI

  https://www.cancer.gov/news-events/cancer-currents-blog/2022/chemo-brain-prevention-s1p

  A significant number of patients who undergo cisplatin treatment are affected by persistent cognitive impairment. […] So, if we can find something that can prevent it, it would really be groundbreaking. […] She said the team will next investigate whether these multiple sclerosis drugs could not just prevent chemo brain symptoms from developing, but also reverse symptoms of cognitive impairment once they have developed. […] More research needs to be done before these drugs could be used to prevent chemotherapy-related cognitive issues in people, Dr. Salvemini stressed. […] We want to look at not only if can we prevent cognitive impairment [in people with cancer], but if we can treat and improve it, she said. […] [The improvement] may not be 100%, but even if we can improve it by 20% or 30% that could have a major impact on somebody’s life.

• #19 Preventing Chemo Brain? Study Identifies Potential Approach for Common Problem – Esophageal Cancer Action Network

  https://ecan.org/2022/11/03/preventing-chemo-brain-study-identifies-potential-approach-for-common-problem/

  A significant number of patients who undergo cisplatin treatment are affected by persistent cognitive impairment[there are] millions of individuals whose daily lives are really impacted, said Dr. Salvemini. So, if we can find something that can prevent it, it would really be groundbreaking. […] The study, led by Daniela Salvemini, Ph.D., and colleagues from the Saint Louis University School of Medicine, also found that treatments that target a brain receptor for S1P and are already approved by the Food and Drug Administration (FDA) to treat multiple sclerosis prevented chemo brain-like symptoms in mice treated with cisplatin. […] More research needs to be done before these drugs could be used to prevent chemotherapy-related cognitive issues in people, Dr. Salvemini stressed. But the fact that they are already FDA approved means the timeline is not like typical drug discovery that takes many years to get into clinical trials, she said. […] We want to look at not only if can we prevent cognitive impairment [in people with cancer], but if we can treat and improve it, she said. [The improvement] may not be 100%, but even if we can improve it by 20% or 30% that could have a major impact on somebody’s life.

• #20 How Long Does Chemo Brain Last?

  https://www.cancercenter.com/community/blog/2023/08/how-long-does-chemo-brain-last

  Researchers are working to find the possible causes of chemo brain and the best way to prevent or treat the symptoms and to reduce their impact and duration. […] Salvemini and the research team at SLU are exploring whether drugs approved to treat MS that target the S1P molecule may also be used to help treat chemo brain. […] Once identified as a potential cause, some of these issues may be directly addressed and treated. […] A study in the Journal of Psychological, Social and Behavioral Dimensions of Cancer confirmed that such mental training exercises are helpful with the 48 study participants experiencing significant cognitive and memory improvements. […] I advise my patients to embrace those lifestyle changes for many more proven reasons such as reduced future cancer risk, with the added benefit that it might help hasten recovery from chemo brain, says Dr. Ahn, adding that laughter is good medicine as well as direct psycho-social support sensitive to patient-specific needs.

• #21 Can 'chemo brain’ be prevented? – Boston Children’s Answers

  https://answers.childrenshospital.org/preventing-chemo-brain/

  Up to three-quarters of patients receiving cancer chemotherapy suffer from “chemo brain” — a side effect that makes it harder to remember things, maintain attention, and learn new information. […] “If we had preventive treatments that could be delivered during therapy, or later in the survivorship phase of care, that would be game-changing for families.” […] Drs. Lehtinen and Kanarek now want to explore the effects of other chemotherapy drugs on the CSF and choroid plexus. […] Antioxidant treatments could potentially come in the form of an IV injection, a nasal spray, or an intrathecal injection, through a spinal tap, directly into the CSF. Such treatments could possibly be given together with the chemotherapy itself. […] “If we could correct the collateral damage of chemotherapy and make even a small improvement in the trajectory of patients’ lives, that would be really exciting.”

• #22 Can 'chemo brain’ be prevented? – Boston Children’s Answers

  https://answers.childrenshospital.org/preventing-chemo-brain/

  Up to three-quarters of patients receiving cancer chemotherapy suffer from “chemo brain” — a side effect that makes it harder to remember things, maintain attention, and learn new information. […] “If we had preventive treatments that could be delivered during therapy, or later in the survivorship phase of care, that would be game-changing for families.” […] Drs. Lehtinen and Kanarek now want to explore the effects of other chemotherapy drugs on the CSF and choroid plexus. […] Antioxidant treatments could potentially come in the form of an IV injection, a nasal spray, or an intrathecal injection, through a spinal tap, directly into the CSF. Such treatments could possibly be given together with the chemotherapy itself. […] “If we could correct the collateral damage of chemotherapy and make even a small improvement in the trajectory of patients’ lives, that would be really exciting.”

• #23 Chemobrain in Cancer Treatment: Mechanisms and Its Prevention | SpringerLink

  https://link.springer.com/10.1007/978-3-030-80962-1_352-1

  Therapeutic use of chemotherapy has led to a significant increase in the number of cancer survivors worldwide. […] Understanding the mechanisms underlying the development of chemobrain would assist the prevention or treatment of the adverse effects of chemotherapy on brain function. […] In addition to considering biological pathways, we also summarize promising therapeutic strategies to alleviate symptoms of chemobrain which have already been proven to provide effective neuroprotection in chemobrain models. […] Physical exercise prevents cognitive impairment by enhancing hippocampal neuroplasticity and mitochondrial function in doxorubicin-induced chemobrain. […] Donepezil protects against doxorubicin-induced Chemobrain in rats via attenuation of inflammation and oxidative stress without interfering with doxorubicin efficacy.

• #24 Chemobrain in Cancer Treatment: Mechanisms and Its Prevention | SpringerLink

  https://link.springer.com/10.1007/978-3-030-80962-1_352-1

  Resveratrol, a natural polyphenol, prevents chemotherapy-induced cognitive impairment: involvement of cytokine modulation and neuroprotection. […] Memantine protects against paclitaxel-induced cognitive impairment through modulation of neurogenesis and inflammation in mice. […] Metformin prevents cisplatin-induced cognitive impairment and brain damage in mice.

• #25 A Potential Therapy for “Chemobrain” | Columbia University Irving Medical Center

  https://www.cuimc.columbia.edu/news/potential-therapy-chemobrain

  Preventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a cancer chemotherapy. Mice are protected from „chemobrain” when the RY34 domain (pink) is positioned as above, which prevents the leak. […] The team tested the idea in mice and found that a chemotherapy treatment causes calcium leaks in the brain and neurocognitive dysfunction in mice with breast cancer and in healthy mice. The leaked calcium inside cells, the team found, impairs neuronal function. […] The good news is that an experimental drug under development in the Marks lab was able to reduce both the calcium leak in the brain and neurocognitive symptoms in mice. […] Marks and his team hope that a clinical trial is soon-to-come, as there is currently no treatment for this common and distressing impairment.

• #26 What Is Chemo Brain, and How Can I Manage It?

  https://www.webmd.com/cancer/manage-chemo-brain

  To avoid misplacing things, place items like your car keys and cellphone in the same place every time you set them down. […] Some people find that taking stimulants like methylphenidate (Quillivant ER, Quillichew ER, Ritalin), a combination of dextroamphetamine and amphetamine (Adderall, Adderall XR), or modafinil/armodafinil (Provigil/Nuvigil) can help their fatigue, attention, and concentration during cancer treatment. However, these medications often have appetite suppression or weight loss as a common side effect, which may be of concern for patients undergoing chemotherapy. Talk to your doctor about whether one of these drugs might work for you. […] Whatever techniques you use, keep your family and friends in the loop. They can be a big source of help and support.

• #27 Cognitive behavioral therapy may help ease 'chemo brain’ – The Washington Post

  https://www.washingtonpost.com/wellness/2023/06/18/chemo-brain-treatment/

  A type of CBT called memory and attention adaptation training is especially effective, Gabel says, and is something that can easily be practiced by patients at home. […] Sleep: A lack of sleep “amplifies the physiological changes that are occurring for somebody who has chemo brain,” Zhou says. […] Mindfulness: Meditation, deep breathing and yoga can improve cognitive complaints, according to a small study of breast cancer patients. […] Psychostimulants: Although there is not yet clinical evidence for their effectiveness, drugs such as Adderall may help. […] Fear of cognitive impairment may lead cancer patients to opt out of treatments, but they shouldn’t, Gabel says. […] “All of this can sound very scary to folks, and I worry that people will turn down treatments that could be curative,” she says.

• #28 What Is Chemo Brain, and How Can I Manage It?

  https://www.webmd.com/cancer/manage-chemo-brain

  To avoid misplacing things, place items like your car keys and cellphone in the same place every time you set them down. […] Some people find that taking stimulants like methylphenidate (Quillivant ER, Quillichew ER, Ritalin), a combination of dextroamphetamine and amphetamine (Adderall, Adderall XR), or modafinil/armodafinil (Provigil/Nuvigil) can help their fatigue, attention, and concentration during cancer treatment. However, these medications often have appetite suppression or weight loss as a common side effect, which may be of concern for patients undergoing chemotherapy. Talk to your doctor about whether one of these drugs might work for you. […] Whatever techniques you use, keep your family and friends in the loop. They can be a big source of help and support.

• #29 Chemo brain: Definition, Symptoms, Causes, and More

  https://www.medicalnewstoday.com/articles/what-is-chemo-brain

  There is currently no way to prevent chemo brain. However, experts believe that certain lifestyle changes may help prevent serious cognitive issues from developing. […] A 2020 review suggests that dietary changes may reduce the toxicity of chemotherapy drugs. Following a healthy diet may decrease chemotherapy side effects like chemo brain. […] Another study from 2021 examined whether exercise could help reduce chemotherapy side effects. Researchers found that regular physical activity may improve cognitive function during and after chemotherapy.

• #30 Physical Activity May Lessen the Effects of Chemo Brain – NCI

  https://www.cancer.gov/news-events/cancer-currents-blog/2021/physical-activity-cognitive-function

  Staying active before and during chemotherapy may help limit the severity of cancer- and treatment-related cognitive issues. […] Research suggests that physical activity may help people with breast cancer avoid some of these problems. […] Now, a large study of people with breast cancer lends further evidence to the idea that staying active during chemotherapy may help limit the severity of cognitive issues that arise. […] These findings could inform early prevention strategies for people diagnosed with breast cancer, such as prescribing a period of regular exercise before starting treatment. […] This study demonstrates the importance of having a baseline level of physical activity before you start chemotherapy. […] Physical activity has been shown to improve cognitive function in healthy older adults, and some studies have suggested that physical activity similarly benefits people with breast cancer undergoing chemotherapy.

• #31 Physical Activity May Lessen the Effects of Chemo Brain – NCI

  https://www.cancer.gov/news-events/cancer-currents-blog/2021/physical-activity-cognitive-function

  Staying active before and during chemotherapy may help limit the severity of cancer- and treatment-related cognitive issues. […] Research suggests that physical activity may help people with breast cancer avoid some of these problems. […] Now, a large study of people with breast cancer lends further evidence to the idea that staying active during chemotherapy may help limit the severity of cognitive issues that arise. […] These findings could inform early prevention strategies for people diagnosed with breast cancer, such as prescribing a period of regular exercise before starting treatment. […] This study demonstrates the importance of having a baseline level of physical activity before you start chemotherapy. […] Physical activity has been shown to improve cognitive function in healthy older adults, and some studies have suggested that physical activity similarly benefits people with breast cancer undergoing chemotherapy.

• #32 Physical Activity May Lessen the Effects of Chemo Brain – NCI

  https://www.cancer.gov/news-events/cancer-currents-blog/2021/physical-activity-cognitive-function

  Patients who were more active before starting chemotherapy performed better on cognitive tests immediately and 6 months after completing chemotherapy than patients who were less active before starting chemotherapy. […] Patients who continued to meet physical activity guidelines before and after chemotherapy had the best cognitive performance across the treatment period. […] Dr. Janelsins said randomized trials with physical activity interventions prior to and during chemotherapy are needed to confirm their findings on the impact of exercise on cognitive functioning. […] Physical activity can have benefits beyond improving cognitive function. […] While we dont know how much activity is needed to improve cognitive functioning, doing something active is better than doing nothing. […] Dr. Janelsins said that people with cancer who are considering starting an exercise program should consult with their health care providers.

• #33 Physical Activity May Lessen the Effects of Chemo Brain – NCI

  https://www.cancer.gov/news-events/cancer-currents-blog/2021/physical-activity-cognitive-function

  Patients who were more active before starting chemotherapy performed better on cognitive tests immediately and 6 months after completing chemotherapy than patients who were less active before starting chemotherapy. […] Patients who continued to meet physical activity guidelines before and after chemotherapy had the best cognitive performance across the treatment period. […] Dr. Janelsins said randomized trials with physical activity interventions prior to and during chemotherapy are needed to confirm their findings on the impact of exercise on cognitive functioning. […] Physical activity can have benefits beyond improving cognitive function. […] While we dont know how much activity is needed to improve cognitive functioning, doing something active is better than doing nothing. […] Dr. Janelsins said that people with cancer who are considering starting an exercise program should consult with their health care providers.

• #34 Physical Activity May Lessen the Effects of Chemo Brain – NCI

  https://www.cancer.gov/news-events/cancer-currents-blog/2021/physical-activity-cognitive-function

  Patients who were more active before starting chemotherapy performed better on cognitive tests immediately and 6 months after completing chemotherapy than patients who were less active before starting chemotherapy. […] Patients who continued to meet physical activity guidelines before and after chemotherapy had the best cognitive performance across the treatment period. […] Dr. Janelsins said randomized trials with physical activity interventions prior to and during chemotherapy are needed to confirm their findings on the impact of exercise on cognitive functioning. […] Physical activity can have benefits beyond improving cognitive function. […] While we dont know how much activity is needed to improve cognitive functioning, doing something active is better than doing nothing. […] Dr. Janelsins said that people with cancer who are considering starting an exercise program should consult with their health care providers.

• #35

• #36 Suffering from

  https://www.health.harvard.edu/blog/suffering-from-chemo-brain-theres-hope-and-many-things-you-can-do-2019112018403

  Some of the most common symptoms experienced by cancer patients are memory problems, difficulties with multitasking, and reduced attention and concentration. […] Research over the past decade has revealed that many cancer patients experience such symptoms as a consequence of specific damage to the brain caused by either their tumor or their treatment. […] While various therapeutic interventions currently remain in clinical testing, there are a number of lifestyle actions that have been found to be effective. […] Regular physical exercise. Cardiovascular exercise is one of the strongest drivers of brain repair after injury, stimulating the growth of new neurons, facilitating connections between brain cells, and enhancing overall cognitive resilience. […] Sufficient restorative sleep. Chronic sleep deprivation damages brain cells, prevents brain regeneration, causes daytime fatigue, and reduces cognitive function.

• #37 Chemobrain in Cancer Treatment: Mechanisms and Its Prevention | SpringerLink

  https://link.springer.com/10.1007/978-3-030-80962-1_352-1

  Therapeutic use of chemotherapy has led to a significant increase in the number of cancer survivors worldwide. […] Understanding the mechanisms underlying the development of chemobrain would assist the prevention or treatment of the adverse effects of chemotherapy on brain function. […] In addition to considering biological pathways, we also summarize promising therapeutic strategies to alleviate symptoms of chemobrain which have already been proven to provide effective neuroprotection in chemobrain models. […] Physical exercise prevents cognitive impairment by enhancing hippocampal neuroplasticity and mitochondrial function in doxorubicin-induced chemobrain. […] Donepezil protects against doxorubicin-induced Chemobrain in rats via attenuation of inflammation and oxidative stress without interfering with doxorubicin efficacy.

• #38 Physical Activity May Lessen the Effects of Chemo Brain – NCI

  https://www.cancer.gov/news-events/cancer-currents-blog/2021/physical-activity-cognitive-function

  Patients who were more active before starting chemotherapy performed better on cognitive tests immediately and 6 months after completing chemotherapy than patients who were less active before starting chemotherapy. […] Patients who continued to meet physical activity guidelines before and after chemotherapy had the best cognitive performance across the treatment period. […] Dr. Janelsins said randomized trials with physical activity interventions prior to and during chemotherapy are needed to confirm their findings on the impact of exercise on cognitive functioning. […] Physical activity can have benefits beyond improving cognitive function. […] While we dont know how much activity is needed to improve cognitive functioning, doing something active is better than doing nothing. […] Dr. Janelsins said that people with cancer who are considering starting an exercise program should consult with their health care providers.

• #39 Suffering from

  https://www.health.harvard.edu/blog/suffering-from-chemo-brain-theres-hope-and-many-things-you-can-do-2019112018403

  Good nutrition. A diet rich in antioxidants can be helpful in minimizing cancer therapy-related damage to brain cells and unwanted cognitive side effects from cancer therapy. […] Engaging in positive and stress-reducing activities. Brain plasticity and nervous system regeneration can be enhanced when all senses are activated, particularly through activities that lead to new experiences and sensations („environmental enrichment”). […] Medications such as neurostimulants and anti-aging drugs may be used in conjunction with lifestyle interventions to improve memory and cognition after cancer treatments. […] A thorough neurological evaluation can be helpful in identifying areas of brain functioning that can be improved with specialized neurocognitive rehabilitation programs. […] Collectively, while symptoms of brain dysfunction are common in cancer patients, there are several interventions that can be considered to help with recovery and enhance healing.

• #40 Chemo brain: Definition, Symptoms, Causes, and More

  https://www.medicalnewstoday.com/articles/what-is-chemo-brain

  There is currently no way to prevent chemo brain. However, experts believe that certain lifestyle changes may help prevent serious cognitive issues from developing. […] A 2020 review suggests that dietary changes may reduce the toxicity of chemotherapy drugs. Following a healthy diet may decrease chemotherapy side effects like chemo brain. […] Another study from 2021 examined whether exercise could help reduce chemotherapy side effects. Researchers found that regular physical activity may improve cognitive function during and after chemotherapy.

• #41 Chemo Brain After Cancer Treatment is Not Imaginary

  https://www.brainandlife.org/articles/cognitive-problems-after-cancer-treatment-are-not-imaginary

  Patients at high risk of chemo brain might benefit from preventive approaches such as cognitive training-brain exercises that teach you how to remember lists of words, as well as reasoning training that helps you recognize number and word patterns. Studies find such approaches can help people without cancer maintain cognitive health, even up to 10 years after the program ends. […] Other preventive options include exercise, which has been shown to prevent chemo brain in mice and overall cognitive decline in healthy individuals; and diets high in antioxidants, like the Mediterranean diet, which is high in whole grains, fruits, vegetables, olive oil, and lean protein. […] Certain medications may also help. Physicians may prescribe psychostimulants like methylphenidate (Ritalin), certain antidepressants, or modafinil (Provigil) or armodafinil (Nuvigil), which are approved for excessive daytime sleepiness.

• #42

  https://www.allinahealth.org/healthysetgo/heal/seven-tips-for-dealing-with-chemo-brain

  You can manage these challenges more effectively if you have realistic expectations, pace tasks throughout the day and week, and allow time for stress reduction and rest. […] Use a calendar, make lists, take notes and set up reminders. […] Good nutrition, proper sleep and moderate exercise are critical for your physical and cognitive recovery. […] A nutritious and balanced diet can help improve your chemo fog symptoms. Some of the best brain foods include green vegetables, berries, walnuts and fatty fish.

• #43

• #44 Chemo Brain – Ironwood Cancer & Research Centers

  https://www.ironwoodcrc.com/chemo-brain/

  Many patients going through chemotherapy treatment report having chemo brain, other cancer treatments like radiation, as well as the cancer itself, can cause similar symptoms that produce problems with memory and thinking. […] To improve memory symptoms and help lower inflammation there are a number of lifestyle approaches that may help. […] The foods you eat can help lower inflammation in the body and provide nutrients to support healthy brain function. […] It is best to avoid or have very limited alcohol which can serve as another toxic insult to brain cells that can impair recovery. […] Having a daily relaxation practice like yoga or mediation can help with focus and mental clarity and lower stress. […] Exercise during and after cancer treatment can help with fatigue and brain function. […] The following supplements have some evidence that they can lower inflammation in the brain which can be beneficial in brain recovery. […] Supporting the healing process through healthy lifestyle modifications can help lower inflammation and improve brain recovery after cancer.

• #45 Suffering from

  https://www.health.harvard.edu/blog/suffering-from-chemo-brain-theres-hope-and-many-things-you-can-do-2019112018403

  Some of the most common symptoms experienced by cancer patients are memory problems, difficulties with multitasking, and reduced attention and concentration. […] Research over the past decade has revealed that many cancer patients experience such symptoms as a consequence of specific damage to the brain caused by either their tumor or their treatment. […] While various therapeutic interventions currently remain in clinical testing, there are a number of lifestyle actions that have been found to be effective. […] Regular physical exercise. Cardiovascular exercise is one of the strongest drivers of brain repair after injury, stimulating the growth of new neurons, facilitating connections between brain cells, and enhancing overall cognitive resilience. […] Sufficient restorative sleep. Chronic sleep deprivation damages brain cells, prevents brain regeneration, causes daytime fatigue, and reduces cognitive function.

• #46 What is Chemo Brain? Its Symptoms & Recovery Methods

  https://actchealth.com/blogs/5-effective-ways-to-recover-from-chemo-brain

  Consider enrolling in mindful therapy workshops or using online resources for assistance and direction. […] 3. Get enough rest […] Cancer treatment can be mentally and physically draining, and chemo brain’s cognitive side effects can make it harder for patients to sleep and maintain their energy levels. Here are some ways for getting enough rest: […] Develop a consistent sleep schedule […] Create a relaxing bedtime routine, such as taking a warm bath, reading a book, or meditation. […] Limit caffeine and alcohol, especially in the evening, as they can interfere with sleep. […] Avoid screen time on your computer or mobile device before going to bed. […] Cancer patients are recommended to consult with their doctor and get a precise schedule for rest hours because staying inactive for longer times can lead to serious health consequences.

• #47 What is chemo brain and how long does it last? | OSF HealthCare

  https://www.osfhealthcare.org/blog/what-is-chemo-brain-and-how-long-does-it-last/

  When you are going through chemotherapy, good hydration can provide some relief from chemo brain. Try to drink 2-3 quarts of fluid the day of treatment and for a few days after to help flush the harmful chemicals out of your system. […] Stress reduction can help, too. People with cancer deal with a lot of medical visits, so their brains are dealing with a lot of information and stress. […] There are many options for stress reduction and cognitive health, so find what works for you. […] Chemo brain can impact your memory, concentration and ability to problem solve for several months after chemotherapy has ended even up to a year. The more you can do to keep your body and mind healthy and active, the better the likelihood is that you can shed the symptoms sooner and avoid these issues turning into long-term effects.

• #48 A noninvasive treatment for “chemo brain” | MIT News | Massachusetts Institute of Technology

  https://news.mit.edu/2024/noninvasive-treatment-chemo-brain-0306

  Stimulating gamma brain waves may protect cancer patients from memory impairment and other cognitive effects of chemotherapy. […] MIT researchers have now shown that a noninvasive treatment that stimulates gamma frequency brain waves may hold promise for treating chemo brain. In a study of mice, they found that daily exposure to light and sound with a frequency of 40 hertz protected brain cells from chemotherapy-induced damage. The treatment also helped to prevent memory loss and impairment of other cognitive functions. […] Tsai says. From our previous work, we know that this gamma sensory stimulation has anti-inflammatory effects, so we decided to use the chemo brain model to test whether sensory gamma stimulation can be beneficial. […] However, mice that received gamma therapy along with cisplatin treatment showed significant reductions in all of those symptoms. The gamma therapy also had beneficial effects on behavior: Mice that received the therapy performed much better on tests designed to measure memory and executive function. […] The researchers also showed that the gamma treatment improved the signs of chemo brain in mice that received a different chemotherapy drug, methotrexate, which is used to treat breast, lung, and other types of cancer.

• #49 A noninvasive treatment for “chemo brain” – ecancer

  https://ecancer.org/en/news/24368-a-noninvasive-treatment-for-chemo-brain

  From our previous work, we know that this gamma sensory stimulation has anti-inflammatory effects, so we decided to use the chemo brain model to test whether sensory gamma stimulation can be beneficial. […] However, mice that received gamma therapy along with cisplatin treatment showed significant reductions in all of those symptoms. […] The gamma therapy also had beneficial effects on behaviour: Mice that received the therapy performed much better on tests designed to measure memory and executive function. […] I think this is a very fundamental mechanism to improve myelination and to promote the integrity of oligodendrocytes. It seems that its not specific to the agent that induces demyelination, be it chemotherapy or another source of demyelination, Tsai says.

• #50 A noninvasive treatment for “chemo brain” – ecancer

  https://ecancer.org/en/news/24368-a-noninvasive-treatment-for-chemo-brain

  From our previous work, we know that this gamma sensory stimulation has anti-inflammatory effects, so we decided to use the chemo brain model to test whether sensory gamma stimulation can be beneficial. […] However, mice that received gamma therapy along with cisplatin treatment showed significant reductions in all of those symptoms. […] The gamma therapy also had beneficial effects on behaviour: Mice that received the therapy performed much better on tests designed to measure memory and executive function. […] I think this is a very fundamental mechanism to improve myelination and to promote the integrity of oligodendrocytes. It seems that its not specific to the agent that induces demyelination, be it chemotherapy or another source of demyelination, Tsai says.

• #51 Chemo Brain After Cancer Treatment is Not Imaginary

  https://www.brainandlife.org/articles/cognitive-problems-after-cancer-treatment-are-not-imaginary

  Patients at high risk of chemo brain might benefit from preventive approaches such as cognitive training-brain exercises that teach you how to remember lists of words, as well as reasoning training that helps you recognize number and word patterns. Studies find such approaches can help people without cancer maintain cognitive health, even up to 10 years after the program ends. […] Other preventive options include exercise, which has been shown to prevent chemo brain in mice and overall cognitive decline in healthy individuals; and diets high in antioxidants, like the Mediterranean diet, which is high in whole grains, fruits, vegetables, olive oil, and lean protein. […] Certain medications may also help. Physicians may prescribe psychostimulants like methylphenidate (Ritalin), certain antidepressants, or modafinil (Provigil) or armodafinil (Nuvigil), which are approved for excessive daytime sleepiness.

• #52 Chemo Brain After Cancer Treatment is Not Imaginary

  https://www.brainandlife.org/articles/cognitive-problems-after-cancer-treatment-are-not-imaginary

  Patients at high risk of chemo brain might benefit from preventive approaches such as cognitive training-brain exercises that teach you how to remember lists of words, as well as reasoning training that helps you recognize number and word patterns. Studies find such approaches can help people without cancer maintain cognitive health, even up to 10 years after the program ends. […] Other preventive options include exercise, which has been shown to prevent chemo brain in mice and overall cognitive decline in healthy individuals; and diets high in antioxidants, like the Mediterranean diet, which is high in whole grains, fruits, vegetables, olive oil, and lean protein. […] Certain medications may also help. Physicians may prescribe psychostimulants like methylphenidate (Ritalin), certain antidepressants, or modafinil (Provigil) or armodafinil (Nuvigil), which are approved for excessive daytime sleepiness.

• #53 What is Chemo Brain? Its Symptoms & Recovery Methods

  https://actchealth.com/blogs/5-effective-ways-to-recover-from-chemo-brain

  4. Play mental games […] Mental exercises can improve memory, focus, and processing speed while also serving as an enjoyable and entertaining diversion during cancer treatment. Here are some good mental games to be considered: […] Crossword puzzles, Sudoku, and other word games […] Memory games, such as Concentration or matching games […] Strategy games, such as chess […] Online trivia games […] 5. Consider cognitive rehabilitation […] It is a form of therapy that focuses on enhancing cognitive function, including memory, attention, and processing speed. Cognitive rehabilitation aims to assist chemo brain patients to regain their cognitive capacities and enhance their general quality of life. […] The therapy program could call for a range of workouts and activities, like: […] Memory training exercises

• #54 Chemo Brain and Cognitive Side Effects – Together by St. Jude™

  https://together.stjude.org/en-us/treatment-tests-procedures/symptoms-side-effects/chemo-brain.html

  Practice mental skills. Chemo brain or cognitive side effects can affect each person differently. Some patients might have more trouble with memory while another might struggle with focus. Find fun ways to work on skills and exercise the mind through games, puzzles, and activities. Make sure to choose age- and ability-appropriate activities.

• #55 Chemo Brain: Online exercises for adults affected by chemo brain- CogniFit

  https://www.cognifit.com/chemo-fog?srsltid=AfmBOoormYbJs2muQxELziQ1wQuad34ehcsh4_IYZ0kfbwpj4fTetCHZ

  Cognitive training for chemo brain […] CogniFit has designed specific cognitive training to strengthen cognitive abilities after cancer treatment and reduce the extent of chemo brain. […] CogniFit’s chemo brain training aims to strengthen cognitive abilities to enhance the quality of life of people who have suffered or are suffering from cancer and who have cognitive symptoms derived from chemotherapy. […] Note: CogniFit does not treat chemo brain, but may help improve cognitive skills affected by this disorder. To optimize results, it is advisable to combine training with other therapies. […] CogniFit’s personalized cognitive training program for chemo brain is made up of a large set of cognitive stimulation and assessment tasks that aim at strengthening the most altered cognitive capacities. […] The cognitive changes that may occur after chemotherapy may vary depending on the type of cancer being treated, as the drug composition may vary and affect the body differently. However, CogniFit has investigated which cognitive abilities are most frequently altered, regardless of the type of cancer, and has created a training that focuses on stimulating these abilities. […] The main goal of CogniFit’s chemo brain training is to enhance the lives of people who have received chemotherapy. To achieve this goal, CogniFit seeks to achieve: Strengthen the brain against the cognitive impairment that a person may suffer after receiving chemotherapy. […] To reduce the cognitive symptoms derived from chemo brain. CogniFit chemo brain activities can help improve a person’s cognitive state who has been through a cancer process. […] Proper training can strengthen our weaknesses and help us improve our performance. […] CogniFit training is based on neuroplasticity to strengthen cognitive skills altered during cancer treatment. […] CogniFit chemo brain cognitive training has been designed to fit the specific cognitive needs of each user. It’s standardized, multi-dimensional and personalized activities make CogniFit a unique and effective cognitive stimulation resource for chemo brain.

• #56 Cancer Side Effects: Tips for Managing Chemo Brain | Nutrition Education Services Center

  https://llsnutrition.org/cancer-side-effects-tips-for-managing-chemo-brain/

  Many cancer survivors report issues during and after cancer treatment including: […] Cognitive issues present many challenges. Because the direct cause of cognitive issues can be unclear, they are difficult to treat. Healthcare professionals are still researching cognitive issues as they relate to cancer and cancer treatment. […] There are some things you can do to manage cognitive side effects. […] Exercise is not only good for your body. It can make you feel better mentally, too. Exercising releases mood-boosting endorphins. […] Anemia can cause cognitive issues. […] Anxiety and stress can cause or worsen cognitive issues. […] Be honest with your friends and family about your “chemo brain.” […] As always, talk to your healthcare team about your side effects and ways to manage them.

• #57 Chemo Brain: What is it & How is it Treated? |

  https://berkeley-institute.com/chemo-brain/

  Chemo brain is a common term used by cancer survivors to describe thinking and memory problems that can occur during and after cancer treatment. […] Symptoms do not usually linger, so doctors rely on medications and mental health methods to mitigate the symptoms. […] There are, however, several ways to cope up with chemo brain naturally. […] Try the following lifestyle changes to ease the symptoms of chemo brain or chemo fog: […] The Regenstrief Institute and the Indiana University School of Medicine recently conducted a study which shows us that a stress reduction program based on mindfulness can create a sustainable improvement to people who suffer from cognitive impairment due to cancer treatments.

• #58 What is Chemo Brain? Its Symptoms & Recovery Methods

  https://actchealth.com/blogs/5-effective-ways-to-recover-from-chemo-brain

  Effective To-dos to Recover from Chemo Brain […] 1. Stay organized […] Staying organized for a day-to-day task can be helpful for chemo brain patients. Some important steps that can help patients are: […] Keep appointments and tasks organized with the help of a planner or calendar. […] Have a notepad or notebook handy to record essential facts. […] When concentrating on a task, reduce distractions by turning off the TV or phone notifications. […] 2. Practice mindfulness […] Mindfulness involves paying attention to the present moment. This can help reduce stress and anxiety, increase focus and attention, and improve overall well-being. Some common ways to practice it are: […] Practice meditation by focusing on your breath and avoiding any physical sensations that arise. […] If suddenly your mind starts to wander, then try to bring your focus back to your breath.

• #59 Get cognitive therapy and coping strategies for chemo brain | OHSU Knight Cancer Institute | Portland, OR

  https://www.ohsu.edu/knight-cancer-institute/chemo-brain

  Chemo brain is a common side effect of cancer and cancer treatment. It is often described as a fog or cloud that interferes with thinking. […] Fortunately, several therapies can help you cope. Tell your care team if you’re concerned about chemo brain. They can help you figure out a plan and refer you to experts and services. […] You can do several things to combat chemo brain and get back to your life. We offer expert support and assistance along the way. […] Ask your care team if cognitive therapy might be right for you. […] We offer several classes in yoga and mindfulness, which lower stress and anxiety while improving sleep and quality of life. We also offer acupuncture for cancer patients. […] It can take a while for your brain to bounce back. In the meantime, here are some tips from our cancer social workers for coping with chemo brain: Set routines. This helps you remember all the things you need to do. Make lists. This helps you stay on track and break big tasks into smaller ones. Set reminders on your phone. Let your phone remember details so you don’t have to. Take regular breaks. This helps focus your attention. Do your thinking when you have energy. No one thinks their best when they’re tired. Have fun. Relaxing and having fun are essential to the healing process.

• #60 Transcranial Magnetic Stimulation for the Treatment of Chemo Brain

  https://www.mdpi.com/1424-8220/23/19/8017

  Transcranial Magnetic Stimulation for the Treatment of Chemo Brain […] This pilot feasibility study aimed to evaluate the effects of transcranial magnetic stimulation (TMS) on chemotherapy-related cognitive impairment (CRCI), and we report here on the first patient. […] Since there is no approved treatment for chemo brain, we have initiated a therapeutic trial using transcranial magnetic stimulation (TMS), a non-invasive brain stimulation technique approved in many countries for the treatment of neurologic and psychiatric conditions like migraine and depression. […] Currently, no treatment is approved for CRCI, and thus research into the understanding and treatment of CRCI needs to keep pace with our improving treatment of cancer. […] Given the unmet need to help patients with “chemo brain” and the proven ability of rTMS to treat neurologic conditions, we initiated a phase 1 clinical trial to assess the feasibility and potential efficacy of rTMS for the treatment of CRCI.

• #61 Transcranial Magnetic Stimulation for the Treatment of Chemo Brain

  https://www.mdpi.com/1424-8220/23/19/8017

  Transcranial Magnetic Stimulation for the Treatment of Chemo Brain […] This pilot feasibility study aimed to evaluate the effects of transcranial magnetic stimulation (TMS) on chemotherapy-related cognitive impairment (CRCI), and we report here on the first patient. […] Since there is no approved treatment for chemo brain, we have initiated a therapeutic trial using transcranial magnetic stimulation (TMS), a non-invasive brain stimulation technique approved in many countries for the treatment of neurologic and psychiatric conditions like migraine and depression. […] Currently, no treatment is approved for CRCI, and thus research into the understanding and treatment of CRCI needs to keep pace with our improving treatment of cancer. […] Given the unmet need to help patients with “chemo brain” and the proven ability of rTMS to treat neurologic conditions, we initiated a phase 1 clinical trial to assess the feasibility and potential efficacy of rTMS for the treatment of CRCI.

• #62 Transcranial Magnetic Stimulation for the Treatment of Chemo Brain

  https://www.mdpi.com/1424-8220/23/19/8017

  The primary aim is to determine the feasibility of iTBS for the treatment of CRCI. A secondary aim is to examine potential efficacy measured by standard neuropsychological testing and functional MRI. Our hypothesis is that excitatory iTBS exerts its effect by improving brain activity at the stimulation locus, thereby potentially eliciting neuroplasticity. […] This first patient in the phase 1 clinical trial testing of TMS for the treatment of “chemo brain” showcased that TMS can be safely administered to individuals with chemo brain, with no significant side effects observed. […] These results show the importance of objective testing for evaluating efficacy, since the patient reported no subjective change in her difficulties with memory and concentration. […] Remarkably, after 6 years of chemo brain and remaining in the same position at work due to her inability to concentrate and multi-task, she applied for and received a promotion 5–6 months after her TMS treatments. […] Our exciting findings have demonstrated that TMS restored the disrupted connectivity of DLPFC. […] These findings align with the hypothesized long-term depression (LTD) and long-term potentiation (LTP)-like plasticity effects.

• #63 Chemo Brain and Cognitive Side Effects – Together by St. Jude™

  https://together.stjude.org/en-us/treatment-tests-procedures/symptoms-side-effects/chemo-brain.html

  Cancer treatments may cause some cognitive changes that may or may not be long lasting. However, there are things families can do to help manage cognitive side effects and promote cognitive health. […] Seek help for cognitive problems. Neuropsychologists, psychologists and learning specialists can help evaluate problems and offer help in navigating school or work. Early intervention is especially important for patients at higher risk for cognitive late effects. Some patients benefit from medications, especially to help with attention and concentration. Medicines being studied for improving cognitive function in cancer patients include methylphenidate (Ritalin) and modafinil (Provigil). […] Practice good health habits. Many health habits that are good for physical health are good for mental health and cognitive function: Exercise, and be active. Eat healthy. Have good sleep habits. Control stress.

• #64 What is Chemo Brain? Its Symptoms & Recovery Methods

  https://actchealth.com/blogs/5-effective-ways-to-recover-from-chemo-brain

  4. Play mental games […] Mental exercises can improve memory, focus, and processing speed while also serving as an enjoyable and entertaining diversion during cancer treatment. Here are some good mental games to be considered: […] Crossword puzzles, Sudoku, and other word games […] Memory games, such as Concentration or matching games […] Strategy games, such as chess […] Online trivia games […] 5. Consider cognitive rehabilitation […] It is a form of therapy that focuses on enhancing cognitive function, including memory, attention, and processing speed. Cognitive rehabilitation aims to assist chemo brain patients to regain their cognitive capacities and enhance their general quality of life. […] The therapy program could call for a range of workouts and activities, like: […] Memory training exercises

• #65 What is Chemo Brain? Its Symptoms & Recovery Methods

  https://actchealth.com/blogs/5-effective-ways-to-recover-from-chemo-brain

  Attention training exercises […] Speech and language exercises […] Visual-spatial training exercises […] Patients who are considering cognitive rehabilitation as a treatment for chemo brain should consult with their physicians. As they will help them to determine the underlying causes of cognitive problems, the severity of symptoms, and the appropriate treatment.

• #66 How to Reverse Chemo Brain | Cognitive FX

  https://www.cognitivefxusa.com/blog/how-to-reverse-chemo-brain

  95% of patients who complete our Enhanced Performance in Cognition (EPIC) Treatment program show statistically verified improvement of their brain function. […] Most healthcare professionals don’t know how your brain, specifically, was affected by chemo. […] Our treatment team includes a neuropsychologist, a neuroscientist, a neuroradiologist, a psychologist, neuromuscular therapists, neurocognitive therapists, neurological occupational therapists, and others. […] There are steps you can take to feel better while you’re at home, too. […] If you haven’t gotten your hormone levels checked since you finished chemo, talk to your doctor and ask for hormone testing. […] Finally, if you’re not sure if your symptoms are from chemo brain but want to learn more, schedule a consultation with our team.

• #67 How to Reverse Chemo Brain | Cognitive FX

  https://www.cognitivefxusa.com/blog/how-to-reverse-chemo-brain

  95% of patients who complete our Enhanced Performance in Cognition (EPIC) Treatment program show statistically verified improvement of their brain function. […] Most healthcare professionals don’t know how your brain, specifically, was affected by chemo. […] Our treatment team includes a neuropsychologist, a neuroscientist, a neuroradiologist, a psychologist, neuromuscular therapists, neurocognitive therapists, neurological occupational therapists, and others. […] There are steps you can take to feel better while you’re at home, too. […] If you haven’t gotten your hormone levels checked since you finished chemo, talk to your doctor and ask for hormone testing. […] Finally, if you’re not sure if your symptoms are from chemo brain but want to learn more, schedule a consultation with our team.

• #68 Chemotherapy Brain Fog (Chemo Brain): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/21032-chemo-brain

  Your healthcare providers choose the treatments that they expect will kill or slow your cancer. They know some of those treatments may affect your memory and your ability to concentrate. Theyll work with you to reduce those side effects as much as they can while effectively treating your condition. […] Healthcare providers have found a few risk factors, most of which you cant control. For example, age and underlying medical conditions may increase your risk of developing chemotherapy brain fog before, during or after receiving cancer treatment.

• #69 Chemotherapy Brain Fog (Chemo Brain): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/21032-chemo-brain

  Your healthcare providers choose the treatments that they expect will kill or slow your cancer. They know some of those treatments may affect your memory and your ability to concentrate. Theyll work with you to reduce those side effects as much as they can while effectively treating your condition. […] Healthcare providers have found a few risk factors, most of which you cant control. For example, age and underlying medical conditions may increase your risk of developing chemotherapy brain fog before, during or after receiving cancer treatment.

• #70 What to know about chemo brain and helpful coping strategies

  https://www.bswhealth.com/blog/what-is-chemo-brain

  So far, there is no known way to prevent the cognitive changes that cause chemo brain, and scientists are still studying the suspected causes. […] Chemo brain seems to happen more often in people who get high doses of chemo and is more likely to occur if the brain is also treated with radiation therapy. […] In most cases, chemo brain is temporary, and the signs usually improve nine to 12 months after completing chemotherapy.

• #71 What to know about chemo brain and helpful coping strategies

  https://www.bswhealth.com/blog/what-is-chemo-brain

  So far, there is no known way to prevent the cognitive changes that cause chemo brain, and scientists are still studying the suspected causes. […] Chemo brain seems to happen more often in people who get high doses of chemo and is more likely to occur if the brain is also treated with radiation therapy. […] In most cases, chemo brain is temporary, and the signs usually improve nine to 12 months after completing chemotherapy.

• #72 Cognitive behavioral therapy may help ease 'chemo brain’ – The Washington Post

  https://www.washingtonpost.com/wellness/2023/06/18/chemo-brain-treatment/

  Neuropsychologists such as Gabel and Eric Zhou, an assistant professor at Harvard Medical School who specializes in disease recovery, say treating chemo brain requires a multipronged approach. […] Zhou urges patients to speak to their doctors as soon as possible about cognitive symptoms. A recent study showed that patients’ symptoms improved with the following interventions: […] Exercise: In a study of more than 500 breast cancer patients, those who exercised for 150 minutes a week maintained cognitive function similar to a control group of those without cancer, says Michelle C. Janelsins-Benton, study author and associate professor at the University of Rochester Medical Center. […] Cognitive behavioral therapy (CBT): Resetting thought patterns and behavior can improve symptoms and make life easier, Zhou says.

• #73 Chemotherapy Brain Fog (Chemo Brain): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/21032-chemo-brain

  Your healthcare providers choose the treatments that they expect will kill or slow your cancer. They know some of those treatments may affect your memory and your ability to concentrate. Theyll work with you to reduce those side effects as much as they can while effectively treating your condition. […] Healthcare providers have found a few risk factors, most of which you cant control. For example, age and underlying medical conditions may increase your risk of developing chemotherapy brain fog before, during or after receiving cancer treatment.

• #74 Cognitive behavioral therapy may help ease 'chemo brain’ – The Washington Post

  https://www.washingtonpost.com/wellness/2023/06/18/chemo-brain-treatment/

  Neuropsychologists such as Gabel and Eric Zhou, an assistant professor at Harvard Medical School who specializes in disease recovery, say treating chemo brain requires a multipronged approach. […] Zhou urges patients to speak to their doctors as soon as possible about cognitive symptoms. A recent study showed that patients’ symptoms improved with the following interventions: […] Exercise: In a study of more than 500 breast cancer patients, those who exercised for 150 minutes a week maintained cognitive function similar to a control group of those without cancer, says Michelle C. Janelsins-Benton, study author and associate professor at the University of Rochester Medical Center. […] Cognitive behavioral therapy (CBT): Resetting thought patterns and behavior can improve symptoms and make life easier, Zhou says.

• #75 Through the Fog: Managing Chemo Brain | Leukemia and Lymphoma Society

  https://www.lls.org/article/through-fog-managing-chemo-brain

  Cognitive issues can be difficult to treat, but there are things you can do to help manage them. […] Talk to your healthcare team. Anemia, shortness of red blood cells, can cause cognitive issues. Ask your healthcare team to check your red blood cell counts if they are not doing so already.

• #76 Cancer Side Effects: Tips for Managing Chemo Brain | Nutrition Education Services Center

  https://llsnutrition.org/cancer-side-effects-tips-for-managing-chemo-brain/

  Many cancer survivors report issues during and after cancer treatment including: […] Cognitive issues present many challenges. Because the direct cause of cognitive issues can be unclear, they are difficult to treat. Healthcare professionals are still researching cognitive issues as they relate to cancer and cancer treatment. […] There are some things you can do to manage cognitive side effects. […] Exercise is not only good for your body. It can make you feel better mentally, too. Exercising releases mood-boosting endorphins. […] Anemia can cause cognitive issues. […] Anxiety and stress can cause or worsen cognitive issues. […] Be honest with your friends and family about your “chemo brain.” […] As always, talk to your healthcare team about your side effects and ways to manage them.

• #77 Chemo Brain and Cognitive Side Effects – Together by St. Jude™

  https://together.stjude.org/en-us/treatment-tests-procedures/symptoms-side-effects/chemo-brain.html

  Cancer treatments may cause some cognitive changes that may or may not be long lasting. However, there are things families can do to help manage cognitive side effects and promote cognitive health. […] Seek help for cognitive problems. Neuropsychologists, psychologists and learning specialists can help evaluate problems and offer help in navigating school or work. Early intervention is especially important for patients at higher risk for cognitive late effects. Some patients benefit from medications, especially to help with attention and concentration. Medicines being studied for improving cognitive function in cancer patients include methylphenidate (Ritalin) and modafinil (Provigil). […] Practice good health habits. Many health habits that are good for physical health are good for mental health and cognitive function: Exercise, and be active. Eat healthy. Have good sleep habits. Control stress.

• #78 Coping with Chemobrain | Side Effect of Chemotherapy

  https://www.cancercare.org/publications/70-coping_with_chemo_brain_keeping_your_memory_sharp

  Chemo brain refers to changes in memory, attention and other mental abilities that come from cancer treatment. […] There is no treatment for chemo brain yet, but there are ways to help its effects. […] If symptoms of chemo brain make you anxious or sad, or they interfere with everyday functioning, dont wait to seek help. […] Speak with an oncology social worker. Oncology social workers, such as those at CancerCare, can help you find ways to cope and connect you to additional resources. […] Tell your doctor about your concerns to deal with contributing factors, such as sleep problems or persistent pain. […] Ask for a referral to a neuropsychologist for an evaluation of your mental and emotional functioning and possible recommendations for treatment. […] Regular physical activity improves blood flow to the brain and is linked to improved memory. […] A healthy diet is good for your body, can make you feel more alert and is linked to lower rates of memory decline. […] Chewing gum can keep you more alert and improve attention and memory.

• #79 Chemo Brain and Cognitive Side Effects – Together by St. Jude™

  https://together.stjude.org/en-us/treatment-tests-procedures/symptoms-side-effects/chemo-brain.html

  Cancer treatments may cause some cognitive changes that may or may not be long lasting. However, there are things families can do to help manage cognitive side effects and promote cognitive health. […] Seek help for cognitive problems. Neuropsychologists, psychologists and learning specialists can help evaluate problems and offer help in navigating school or work. Early intervention is especially important for patients at higher risk for cognitive late effects. Some patients benefit from medications, especially to help with attention and concentration. Medicines being studied for improving cognitive function in cancer patients include methylphenidate (Ritalin) and modafinil (Provigil). […] Practice good health habits. Many health habits that are good for physical health are good for mental health and cognitive function: Exercise, and be active. Eat healthy. Have good sleep habits. Control stress.

• #80 Chemo Brain | HealthLink BC

  https://www.healthlinkbc.ca/healthwise/chemo-brain

  Keep your brain active by reading and doing puzzles, games, or crosswords. […] Use sticky notes and calendars to help you remember events and tasks. […] Keep a diary or journal. Write down when your mind feels the most clear and when you have trouble. Note how much sleep you had, if you were stressed, or other things that happened. These notes may help your doctor suggest more things to help you. […] See an oncology social worker if you are having trouble coping with memory problems. […] Think about joining a support group for people in cancer treatment. They may have the same problems. You can share coping ideas.

• #81 How Long Does Chemo Brain Last?

  https://www.cancercenter.com/community/blog/2023/08/how-long-does-chemo-brain-last

  Other ways to manage chemo brain include: […] Talking to your doctor about the side effects of cancer treatment and what you can do to help mitigate symptoms. […] Getting cognitive rehabilitation, which may involve a cognitive therapist like Karens, who may recommend mental exercise or tools like daily planners. […] Keeping a diary of when you notice problems and whats going on at the time, including any medicines taken. This record will also be useful when you talk with your doctor and might help you figure out what prompts your symptoms.

• #82 How to Reverse Chemo Brain | Cognitive FX

  https://www.cognitivefxusa.com/blog/how-to-reverse-chemo-brain

  Cognitive impairment after chemotherapy is a real medical condition, and it is treatable. […] Treatment for chemo brain is relatively new. But that doesn’t mean you shouldn’t have access to it. […] If you have completed your cancer treatment and want to reverse chemo brain, sign up for a consultation with our team. […] If your cognitive problems and other symptoms persist six months after you stop chemotherapy, you may want to seek treatment. […] If you still have chemo brain twelve months after ending cancer treatment, we strongly recommend seeking medical assistance. […] While you’re waiting, we recommend that you try some at-home strategies. […] Cognitive rehabilitation is one of the treatment options mentioned by the American Cancer Society (ACS). […] At Cognitive FX, we offer a robust treatment protocol for invisible brain injuries such as chemo brain.

• #83 How to Reverse Chemo Brain | Cognitive FX

  https://www.cognitivefxusa.com/blog/how-to-reverse-chemo-brain

  Cognitive impairment after chemotherapy is a real medical condition, and it is treatable. […] Treatment for chemo brain is relatively new. But that doesn’t mean you shouldn’t have access to it. […] If you have completed your cancer treatment and want to reverse chemo brain, sign up for a consultation with our team. […] If your cognitive problems and other symptoms persist six months after you stop chemotherapy, you may want to seek treatment. […] If you still have chemo brain twelve months after ending cancer treatment, we strongly recommend seeking medical assistance. […] While you’re waiting, we recommend that you try some at-home strategies. […] Cognitive rehabilitation is one of the treatment options mentioned by the American Cancer Society (ACS). […] At Cognitive FX, we offer a robust treatment protocol for invisible brain injuries such as chemo brain.

• #84 Coping with Chemobrain | Side Effect of Chemotherapy

  https://www.cancercare.org/publications/70-coping_with_chemo_brain_keeping_your_memory_sharp

  Chemo brain refers to changes in memory, attention and other mental abilities that come from cancer treatment. […] There is no treatment for chemo brain yet, but there are ways to help its effects. […] If symptoms of chemo brain make you anxious or sad, or they interfere with everyday functioning, dont wait to seek help. […] Speak with an oncology social worker. Oncology social workers, such as those at CancerCare, can help you find ways to cope and connect you to additional resources. […] Tell your doctor about your concerns to deal with contributing factors, such as sleep problems or persistent pain. […] Ask for a referral to a neuropsychologist for an evaluation of your mental and emotional functioning and possible recommendations for treatment. […] Regular physical activity improves blood flow to the brain and is linked to improved memory. […] A healthy diet is good for your body, can make you feel more alert and is linked to lower rates of memory decline. […] Chewing gum can keep you more alert and improve attention and memory.

• #85 A Potential Therapy for “Chemobrain” | Columbia University Irving Medical Center

  https://www.cuimc.columbia.edu/news/potential-therapy-chemobrain

  Preventing chemobrain. A leak of calcium through the ryanodine receptor (above) in the brain led to neurocognitive dysfunction in mice treated with a cancer chemotherapy. Mice are protected from „chemobrain” when the RY34 domain (pink) is positioned as above, which prevents the leak. […] The team tested the idea in mice and found that a chemotherapy treatment causes calcium leaks in the brain and neurocognitive dysfunction in mice with breast cancer and in healthy mice. The leaked calcium inside cells, the team found, impairs neuronal function. […] The good news is that an experimental drug under development in the Marks lab was able to reduce both the calcium leak in the brain and neurocognitive symptoms in mice. […] Marks and his team hope that a clinical trial is soon-to-come, as there is currently no treatment for this common and distressing impairment.

• #86 Cognitive behavioral therapy may help ease 'chemo brain’ – The Washington Post

  https://www.washingtonpost.com/wellness/2023/06/18/chemo-brain-treatment/

  No Food and Drug Administration-approved medications are available for chemo brain, although Mandelblatt predicts it won’t be long before physicians can offer pharmaceutical solutions to their patients. […] “We are making some progress, and I expect that already approved drugs will be repurposed for chemo brain,” says Mandelblatt, noting that studies in mice show promise.

• #87 Chemobrain in Cancer Treatment: Mechanisms and Its Prevention | SpringerLink

  https://link.springer.com/10.1007/978-3-030-80962-1_352-1

  Therapeutic use of chemotherapy has led to a significant increase in the number of cancer survivors worldwide. […] Understanding the mechanisms underlying the development of chemobrain would assist the prevention or treatment of the adverse effects of chemotherapy on brain function. […] In addition to considering biological pathways, we also summarize promising therapeutic strategies to alleviate symptoms of chemobrain which have already been proven to provide effective neuroprotection in chemobrain models. […] Physical exercise prevents cognitive impairment by enhancing hippocampal neuroplasticity and mitochondrial function in doxorubicin-induced chemobrain. […] Donepezil protects against doxorubicin-induced Chemobrain in rats via attenuation of inflammation and oxidative stress without interfering with doxorubicin efficacy.

• #88 How Long Does Chemo Brain Last?

  https://www.cancercenter.com/community/blog/2023/08/how-long-does-chemo-brain-last

  Researchers are working to find the possible causes of chemo brain and the best way to prevent or treat the symptoms and to reduce their impact and duration. […] Salvemini and the research team at SLU are exploring whether drugs approved to treat MS that target the S1P molecule may also be used to help treat chemo brain. […] Once identified as a potential cause, some of these issues may be directly addressed and treated. […] A study in the Journal of Psychological, Social and Behavioral Dimensions of Cancer confirmed that such mental training exercises are helpful with the 48 study participants experiencing significant cognitive and memory improvements. […] I advise my patients to embrace those lifestyle changes for many more proven reasons such as reduced future cancer risk, with the added benefit that it might help hasten recovery from chemo brain, says Dr. Ahn, adding that laughter is good medicine as well as direct psycho-social support sensitive to patient-specific needs.

• #89 Transcranial Magnetic Stimulation for the Treatment of Chemo Brain

  https://www.mdpi.com/1424-8220/23/19/8017

  Transcranial Magnetic Stimulation for the Treatment of Chemo Brain […] This pilot feasibility study aimed to evaluate the effects of transcranial magnetic stimulation (TMS) on chemotherapy-related cognitive impairment (CRCI), and we report here on the first patient. […] Since there is no approved treatment for chemo brain, we have initiated a therapeutic trial using transcranial magnetic stimulation (TMS), a non-invasive brain stimulation technique approved in many countries for the treatment of neurologic and psychiatric conditions like migraine and depression. […] Currently, no treatment is approved for CRCI, and thus research into the understanding and treatment of CRCI needs to keep pace with our improving treatment of cancer. […] Given the unmet need to help patients with “chemo brain” and the proven ability of rTMS to treat neurologic conditions, we initiated a phase 1 clinical trial to assess the feasibility and potential efficacy of rTMS for the treatment of CRCI.

• #90 Physical Activity May Lessen the Effects of Chemo Brain – NCI

  https://www.cancer.gov/news-events/cancer-currents-blog/2021/physical-activity-cognitive-function

  Patients who were more active before starting chemotherapy performed better on cognitive tests immediately and 6 months after completing chemotherapy than patients who were less active before starting chemotherapy. […] Patients who continued to meet physical activity guidelines before and after chemotherapy had the best cognitive performance across the treatment period. […] Dr. Janelsins said randomized trials with physical activity interventions prior to and during chemotherapy are needed to confirm their findings on the impact of exercise on cognitive functioning. […] Physical activity can have benefits beyond improving cognitive function. […] While we dont know how much activity is needed to improve cognitive functioning, doing something active is better than doing nothing. […] Dr. Janelsins said that people with cancer who are considering starting an exercise program should consult with their health care providers.

• #91 Fat Molecule in Brain Linked to Chemo Brain – NCI

  https://www.cancer.gov/news-events/cancer-currents-blog/2022/chemo-brain-prevention-s1p

  A significant number of patients who undergo cisplatin treatment are affected by persistent cognitive impairment. […] So, if we can find something that can prevent it, it would really be groundbreaking. […] She said the team will next investigate whether these multiple sclerosis drugs could not just prevent chemo brain symptoms from developing, but also reverse symptoms of cognitive impairment once they have developed. […] More research needs to be done before these drugs could be used to prevent chemotherapy-related cognitive issues in people, Dr. Salvemini stressed. […] We want to look at not only if can we prevent cognitive impairment [in people with cancer], but if we can treat and improve it, she said. […] [The improvement] may not be 100%, but even if we can improve it by 20% or 30% that could have a major impact on somebody’s life.

• #92 Can 'chemo brain’ be prevented? – Boston Children’s Answers

  https://answers.childrenshospital.org/preventing-chemo-brain/

  Up to three-quarters of patients receiving cancer chemotherapy suffer from “chemo brain” — a side effect that makes it harder to remember things, maintain attention, and learn new information. […] “If we had preventive treatments that could be delivered during therapy, or later in the survivorship phase of care, that would be game-changing for families.” […] Drs. Lehtinen and Kanarek now want to explore the effects of other chemotherapy drugs on the CSF and choroid plexus. […] Antioxidant treatments could potentially come in the form of an IV injection, a nasal spray, or an intrathecal injection, through a spinal tap, directly into the CSF. Such treatments could possibly be given together with the chemotherapy itself. […] “If we could correct the collateral damage of chemotherapy and make even a small improvement in the trajectory of patients’ lives, that would be really exciting.”

• #93 Fat Molecule in Brain Linked to Chemo Brain – NCI

  https://www.cancer.gov/news-events/cancer-currents-blog/2022/chemo-brain-prevention-s1p

  A significant number of patients who undergo cisplatin treatment are affected by persistent cognitive impairment. […] So, if we can find something that can prevent it, it would really be groundbreaking. […] She said the team will next investigate whether these multiple sclerosis drugs could not just prevent chemo brain symptoms from developing, but also reverse symptoms of cognitive impairment once they have developed. […] More research needs to be done before these drugs could be used to prevent chemotherapy-related cognitive issues in people, Dr. Salvemini stressed. […] We want to look at not only if can we prevent cognitive impairment [in people with cancer], but if we can treat and improve it, she said. […] [The improvement] may not be 100%, but even if we can improve it by 20% or 30% that could have a major impact on somebody’s life.

• #94 Can 'chemo brain’ be prevented? – Boston Children’s Answers

  https://answers.childrenshospital.org/preventing-chemo-brain/

  Up to three-quarters of patients receiving cancer chemotherapy suffer from “chemo brain” — a side effect that makes it harder to remember things, maintain attention, and learn new information. […] “If we had preventive treatments that could be delivered during therapy, or later in the survivorship phase of care, that would be game-changing for families.” […] Drs. Lehtinen and Kanarek now want to explore the effects of other chemotherapy drugs on the CSF and choroid plexus. […] Antioxidant treatments could potentially come in the form of an IV injection, a nasal spray, or an intrathecal injection, through a spinal tap, directly into the CSF. Such treatments could possibly be given together with the chemotherapy itself. […] “If we could correct the collateral damage of chemotherapy and make even a small improvement in the trajectory of patients’ lives, that would be really exciting.”

• #95 Can 'chemo brain’ be prevented? – Boston Children’s Answers

  https://answers.childrenshospital.org/preventing-chemo-brain/

  Up to three-quarters of patients receiving cancer chemotherapy suffer from “chemo brain” — a side effect that makes it harder to remember things, maintain attention, and learn new information. […] “If we had preventive treatments that could be delivered during therapy, or later in the survivorship phase of care, that would be game-changing for families.” […] Drs. Lehtinen and Kanarek now want to explore the effects of other chemotherapy drugs on the CSF and choroid plexus. […] Antioxidant treatments could potentially come in the form of an IV injection, a nasal spray, or an intrathecal injection, through a spinal tap, directly into the CSF. Such treatments could possibly be given together with the chemotherapy itself. […] “If we could correct the collateral damage of chemotherapy and make even a small improvement in the trajectory of patients’ lives, that would be really exciting.”

• #96 Chemo Brain | HealthLink BC

  https://www.healthlinkbc.ca/healthwise/chemo-brain

  Chemo brain is a problem with thinking and memory that can happen during and especially after chemotherapy treatment for cancer. […] Research is ongoing to learn more about how chemo brain occurs and how to prevent and treat it. […] Studies are being done to see which cancer medicines might be less likely to cause these problems. […] If you still have chemo brain a year after cancer treatment ends, your doctor may suggest that you see a neuropsychologist. These experts help people who have cognitive problems. […] Here are some ideas that may help you cope with this problem. […] Try to relax to reduce your stress. Meditate, or do yoga or another relaxing activity. […] Get plenty of sleep. […] Eat a healthy diet. […] Be as physically active as you can. But check with your doctor to make sure that you don’t do too much too soon.

• #97 Cognitive behavioral therapy may help ease 'chemo brain’ – The Washington Post

  https://www.washingtonpost.com/wellness/2023/06/18/chemo-brain-treatment/

  No Food and Drug Administration-approved medications are available for chemo brain, although Mandelblatt predicts it won’t be long before physicians can offer pharmaceutical solutions to their patients. […] “We are making some progress, and I expect that already approved drugs will be repurposed for chemo brain,” says Mandelblatt, noting that studies in mice show promise.

• #98 Get cognitive therapy and coping strategies for chemo brain | OHSU Knight Cancer Institute | Portland, OR

  https://www.ohsu.edu/knight-cancer-institute/chemo-brain

  Chemo brain is a common side effect of cancer and cancer treatment. It is often described as a fog or cloud that interferes with thinking. […] Fortunately, several therapies can help you cope. Tell your care team if you’re concerned about chemo brain. They can help you figure out a plan and refer you to experts and services. […] You can do several things to combat chemo brain and get back to your life. We offer expert support and assistance along the way. […] Ask your care team if cognitive therapy might be right for you. […] We offer several classes in yoga and mindfulness, which lower stress and anxiety while improving sleep and quality of life. We also offer acupuncture for cancer patients. […] It can take a while for your brain to bounce back. In the meantime, here are some tips from our cancer social workers for coping with chemo brain: Set routines. This helps you remember all the things you need to do. Make lists. This helps you stay on track and break big tasks into smaller ones. Set reminders on your phone. Let your phone remember details so you don’t have to. Take regular breaks. This helps focus your attention. Do your thinking when you have energy. No one thinks their best when they’re tired. Have fun. Relaxing and having fun are essential to the healing process.

• #99 Suffering from

  https://www.health.harvard.edu/blog/suffering-from-chemo-brain-theres-hope-and-many-things-you-can-do-2019112018403

  Some of the most common symptoms experienced by cancer patients are memory problems, difficulties with multitasking, and reduced attention and concentration. […] Research over the past decade has revealed that many cancer patients experience such symptoms as a consequence of specific damage to the brain caused by either their tumor or their treatment. […] While various therapeutic interventions currently remain in clinical testing, there are a number of lifestyle actions that have been found to be effective. […] Regular physical exercise. Cardiovascular exercise is one of the strongest drivers of brain repair after injury, stimulating the growth of new neurons, facilitating connections between brain cells, and enhancing overall cognitive resilience. […] Sufficient restorative sleep. Chronic sleep deprivation damages brain cells, prevents brain regeneration, causes daytime fatigue, and reduces cognitive function.

• #100 Suffering from

  https://www.health.harvard.edu/blog/suffering-from-chemo-brain-theres-hope-and-many-things-you-can-do-2019112018403

  Good nutrition. A diet rich in antioxidants can be helpful in minimizing cancer therapy-related damage to brain cells and unwanted cognitive side effects from cancer therapy. […] Engaging in positive and stress-reducing activities. Brain plasticity and nervous system regeneration can be enhanced when all senses are activated, particularly through activities that lead to new experiences and sensations („environmental enrichment”). […] Medications such as neurostimulants and anti-aging drugs may be used in conjunction with lifestyle interventions to improve memory and cognition after cancer treatments. […] A thorough neurological evaluation can be helpful in identifying areas of brain functioning that can be improved with specialized neurocognitive rehabilitation programs. […] Collectively, while symptoms of brain dysfunction are common in cancer patients, there are several interventions that can be considered to help with recovery and enhance healing.

• #101 Memory and concentration | Maggie’s

  https://www.maggies.org/cancer-support/managing-symptoms-and-side-effects/memory-and-concentration/

  Some people notice that they are more forgetful or have trouble concentrating or making decisions after treatment for cancer. […] Although commonly called chemo brain, this can occur after different types of treatment for cancer. Recent research has shown that it may result more from the stress of diagnosis and treatment than the treatment itself. […] There is no specific treatment for chemo brain. However, there are other side effects from treatment that can add to its symptoms, and they can be treated. […] Exercise can reduce stress, fatigue and depression; recent research has also shown exercise to help improve memory in women treated for breast cancer. […] Nutrition: Eating healthily can improve mood and fatigue and keep blood sugar levels stable, all of which can help improve memory and concentration.

• #102 Memory and concentration | Maggie’s

  https://www.maggies.org/cancer-support/managing-symptoms-and-side-effects/memory-and-concentration/

  Complementary therapies such as herbal medicine and acupuncture have been shown to be helpful in reducing stress and boosting memory and concentration. […] If you’re finding that the fogginess is causing you anxiety, affecting your ability to carry out essential tasks or continued for longer than expected, then do let your healthcare team know.

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