Materiały źródłowe

• #1 Autonomic neuropathy: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000776.htm

  Autonomic neuropathy is a group of symptoms that occur when there is damage to the nerves that manage normally automatic body functions. These functions include blood pressure, heart rate, sweating, bowel and bladder emptying, and digestion. The nerves are part of the autonomic nervous system. […] Symptoms vary, depending on the nerves affected. They usually develop slowly over years. […] Early symptoms might include: Becoming faint or lightheaded when standing, Changes in bowel, bladder, or sexual function, Unexplained nausea and vomiting when eating. […] How well you do will depend on the cause of the problem and if it can be treated.

• #2 Autonomic neuropathy | Lima Memorial Health System

  https://www.limamemorial.org/health-library/hie%20multimedia-textonly/1/000776

  Autonomic neuropathy is a group of symptoms that occur when there is damage to the nerves that manage normally automatic body functions. These functions include blood pressure, heart rate, sweating, bowel and bladder emptying, and digestion. The nerves are part of the autonomic nervous system. […] Symptoms vary, depending on the nerves affected. They usually develop slowly over years. […] Early symptoms might include: Becoming faint or lightheaded when standing, Changes in bowel, bladder, or sexual function, Unexplained nausea and vomiting when eating. […] Autonomic neuropathy may hide the warning signs of a heart attack. Instead of feeling chest pain, if you have autonomic neuropathy, during a heart attack you may only have: Sudden fatigue, Sweating, Shortness of breath, Nausea and vomiting.

• #3 Autonomic neuropathy: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000776.htm

  Autonomic neuropathy is a group of symptoms that occur when there is damage to the nerves that manage normally automatic body functions. These functions include blood pressure, heart rate, sweating, bowel and bladder emptying, and digestion. The nerves are part of the autonomic nervous system. […] Symptoms vary, depending on the nerves affected. They usually develop slowly over years. […] Early symptoms might include: Becoming faint or lightheaded when standing, Changes in bowel, bladder, or sexual function, Unexplained nausea and vomiting when eating. […] How well you do will depend on the cause of the problem and if it can be treated.

• #4 Autonomic Neuropathy: Causes, and Treatment | Doctor

  https://patient.info/doctor/autonomic-neuropathy

  Autonomic neuropathy affects the autonomic neurons of either or both of the parasympathetic and sympathetic nervous systems. […] Several syndromes and diseases exhibit autonomic neuropathies and there is a wide variety of clinical features and presentations. […] In some patients the features are subclinical, whereas in others the dysfunction leads to significant disability. […] Autonomic neuropathies represent a complex group of disorders that preferentially target autonomic fibres and can be classified as either acute/subacute or chronic in onset. […] Of the chronic-onset forms, diabetes is the most widespread and disabling, with autonomic impairment leading to increased mortality. […] Autonomic nervous system dysfunction may present with a variety of symptoms. Orthostatic intolerance (including orthostatic hypotension or tachycardia) and sweating abnormalities (increased or decreased sweating) are common problems.

• #5 Autonomic Neuropathy: Background, Pathophysiology, Inherited Autonomic Neuropathies

  https://emedicine.medscape.com/article/1173756-overview

  Autonomic neuropathies are a collection of syndromes and diseases affecting the autonomic neurons, either parasympathetic or sympathetic, or both. […] The autonomic nervous system modulates numerous body functions; therefore, autonomic dysfunction may manifest with numerous clinical phenotypes and various laboratory and neurophysiologic abnormalities. […] In some patients, the degree of autonomic dysfunction may be subclinical or clinically irrelevant; in others, symptoms may be disabling. […] Several clinically important features of autonomic neuropathies are treatable; therefore, the physician must be alert to these features. […] The prognosis depends on the particular syndrome causing autonomic neuropathy. In many cases, the course is gradually progressive in nature. […] In specific cases, the prognosis may be improved by controlling diabetes mellitus, limiting alcohol intake, and treating correctable syndromes or diseases as applicable to prevent progression. […] In the case of acute autonomic neuropathies, such as acute pandysautonomia and GBS, the prognosis is often good after resolution of the acute illness.

• #6 Autonomic neuropathy: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000776.htm

  Autonomic neuropathy is a group of symptoms that occur when there is damage to the nerves that manage normally automatic body functions. These functions include blood pressure, heart rate, sweating, bowel and bladder emptying, and digestion. The nerves are part of the autonomic nervous system. […] Symptoms vary, depending on the nerves affected. They usually develop slowly over years. […] Early symptoms might include: Becoming faint or lightheaded when standing, Changes in bowel, bladder, or sexual function, Unexplained nausea and vomiting when eating. […] How well you do will depend on the cause of the problem and if it can be treated.

• #7 Autonomic neuropathy | Lima Memorial Health System

  https://www.limamemorial.org/health-library/hie%20multimedia-textonly/1/000776

  Autonomic neuropathy is a group of symptoms that occur when there is damage to the nerves that manage normally automatic body functions. These functions include blood pressure, heart rate, sweating, bowel and bladder emptying, and digestion. The nerves are part of the autonomic nervous system. […] Symptoms vary, depending on the nerves affected. They usually develop slowly over years. […] Early symptoms might include: Becoming faint or lightheaded when standing, Changes in bowel, bladder, or sexual function, Unexplained nausea and vomiting when eating. […] Autonomic neuropathy may hide the warning signs of a heart attack. Instead of feeling chest pain, if you have autonomic neuropathy, during a heart attack you may only have: Sudden fatigue, Sweating, Shortness of breath, Nausea and vomiting.

• #8 Stages of Autonomic Dysfunction – Nemechek Autonomic Medicine

  https://www.nemechekconsultativemedicine.com/stages/

  Autonomic Dysfunction includes heartburn, headaches, high blood pressure, sleep apnea or insomnia, and cerebral blood flow issues that create ADD, chronic hunger or chronic fatigue. […] Early Autonomic Dysfunction in adults includes high blood pressure, sleep apnea or insomnia, and cerebral blood flow issues that leave us with ADD, chronic hunger or chronic fatigue. It is abnormal heart rhythms and frequent urination. It is also unexplained anxiety, dizziness or feeling lightheaded, insomnia or waking up in the night, poor memory, poor focus, and power surges when you should be at rest. […] Autonomic Dysfunction causes people to experience heartburn, headaches, intestinal distress, dizziness, excessive hunger or thirst, anxiety, sexual dysfunction, or poor sleep. […] The progression of Autonomic Dysfunction brings the inability to control the blood pressure and heart rates (A-fib, flutter, palpitations, POTS), affects the forward movement of the digestive tract, and proper breathing (sleep apnea). People experience problems with their immune system, hormone levels, and organ function. People no longer bounce back from illnesses or injury and may suffer from chronic fatigue or chronic pain.

• #9 Autonomic Neuropathy – NIDDK

  https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/nerve-damage-diabetic-neuropathies/autonomic-neuropathy

  Autonomic neuropathy can lead to problems with your heart rate and blood pressure. […] The symptoms of autonomic neuropathy depend on which of your body’s functions are affected. […] Damage to the nerves that control your heart rate and blood pressure may make these nerves respond more slowly to a change in your body’s position, stress, physical activity, sleep, and breathing patterns. […] Damage to the nerves of your digestive system can cause symptoms such as bloating, fullness, and nausea, constipation, diarrhea, especially at night, diarrhea alternating with constipation, fecal incontinence, problems swallowing, and vomiting. […] Autonomic neuropathy may also cause gastroparesis. […] Damage to the nerves of your bladder may make it hard to know when you need to urinate and when your bladder is empty.

• #10 Autonomic neuropathy – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/autonomic-neuropathy/symptoms-causes/syc-20369829

  Autonomic neuropathy occurs when there is damage to the nerves that control automatic body functions. It can affect blood pressure, temperature control, digestion, bladder function and even sexual function. […] Signs and symptoms of autonomic neuropathy depend on which nerves are damaged. They might include: Dizziness and fainting when standing, caused by a sudden drop in blood pressure. Urinary problems, such as difficulty starting urination, loss of bladder control, difficulty sensing a full bladder and inability to completely empty the bladder. Not being able to completely empty the bladder can lead to urinary tract infections. Sexual difficulties, including problems achieving or maintaining an erection (erectile dysfunction) or ejaculation problems. In women, problems include vaginal dryness, low libido and difficulty reaching orgasm. Difficulty digesting food, such as feeling full after a few bites of food, loss of appetite, diarrhea, constipation, abdominal bloating, nausea, vomiting, difficulty swallowing and heartburn. These problems are all due to changes in digestive function. Inability to recognize low blood sugar (hypoglycemia), because the warning signals, such as getting shaky, aren’t there. Sweating problems, such as sweating too much or too little. These problems affect the ability to regulate body temperature. Sluggish pupil reaction, making it difficult to adjust from light to dark and seeing well when driving at night. Exercise intolerance, which can occur if your heart rate stays the same instead of adjusting to your activity level.

• #11

  https://www.aurorahealthcare.org/services/neuroscience/neurology/neurological-conditions/autonomic-neuropathy

  Autonomic neuropathy disrupts the nerves governing autonomic bodily functions, impacting systems like body temperature, blood pressure and bladder control. […] Symptoms of autonomic neuropathy can vary depending on the affected nerves and may include problems with heart rate and blood pressure, difficulties in digestion, urinary problems, sexual issues and sweat abnormalities. […] Other symptoms may encompass changes in body temperature, troubles with vision, and difficulties in managing blood glucose levels. […] Common autonomic neuropathy symptoms may include: Abnormal heart rate, Blurred vision, Changes in blood pressure, Diarrhea or constipation, Difficulty adjusting to light/dark changes, Difficulty breathing, Difficulty emptying the bladder or incontinence, Difficulty swallowing, Excessive sweating or lack of sweating, Fainting or lightheadedness upon standing, Nausea and vomiting, Problems with body temperature regulation, leading to intolerance to heat or cold, Sexual dysfunction, Shallow breathing, Trouble emptying your stomach. […] Symptoms may differ among individuals, and the intensity could be influenced by the degree of nerve damage. […] Autonomic neuropathy can also be associated with various underlying conditions, such as diabetes, autoimmune diseases or certain types of infections.

• #12 Autonomic Neuropathy: Definition, Symptoms, Treatments

  https://resources.healthgrades.com/right-care/symptoms-and-conditions/autonomic-neuropathy

  Autonomic neuropathy is a type of nerve damage that affects internal organs. Diabetes is a common cause of autonomic neuropathy. Your autonomic nervous system controls involuntary functions in your body, such as digestion, heart rate, and sexual arousal. Autonomic neuropathy occurs when the nerves of internal organs become damaged, causing a change in function. […] Autonomic neuropathy, or autonomic small fiber neuropathy, is damage to nerves that control internal organs. As nerve damage progresses, it disrupts the function of the organ. […] Symptoms of autonomic neuropathy vary depending on the area affected by nerve damage. […] Damage to heart and vascular nerves can cause symptoms of CAN including elevated resting heart rate, dizziness if you stand up too quickly, sudden fainting for no apparent reason, especially after standing up or changing position, heart attack without typical symptoms, such as chest pain or tightness.

• #13 Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5763036/

  Development of OH is associated with severe or advanced CAN and prescription of nonpharmacological and pharmacological, in the foreground midodrine and fludrocortisone acetate, treatment methods are necessary. […] CAN is strongly associated with increased mortality, and in some studies with morbidity, such as stroke, coronary artery disease (CAD) and SMI. […] Development of autonomic dysfunction in T1DM is accompanied by the four time higher risk of mortality. […] There is definitive evidence for a predictive value of CAN on overall mortality (class I) and some evidence on morbidity (class II). Prolongation of QTi (class II), tachycardia (class II) and non-dipping status (class III) are associated with increased mortality rate. […] The main predictors for the development of CAN in patients with T2DM are age, gender, ethnicity and presence of microvascular complications [nephropathy, retinopathy, and peripheral neuropathy (PNP)].

• #14 Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5763036/

  Development of OH is associated with severe or advanced CAN and prescription of nonpharmacological and pharmacological, in the foreground midodrine and fludrocortisone acetate, treatment methods are necessary. […] CAN is strongly associated with increased mortality, and in some studies with morbidity, such as stroke, coronary artery disease (CAD) and SMI. […] Development of autonomic dysfunction in T1DM is accompanied by the four time higher risk of mortality. […] There is definitive evidence for a predictive value of CAN on overall mortality (class I) and some evidence on morbidity (class II). Prolongation of QTi (class II), tachycardia (class II) and non-dipping status (class III) are associated with increased mortality rate. […] The main predictors for the development of CAN in patients with T2DM are age, gender, ethnicity and presence of microvascular complications [nephropathy, retinopathy, and peripheral neuropathy (PNP)].

• #15 Autonomic Neuropathy – NIDDK

  https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/nerve-damage-diabetic-neuropathies/autonomic-neuropathy

  Autonomic neuropathy can lead to problems with your heart rate and blood pressure. […] The symptoms of autonomic neuropathy depend on which of your body’s functions are affected. […] Damage to the nerves that control your heart rate and blood pressure may make these nerves respond more slowly to a change in your body’s position, stress, physical activity, sleep, and breathing patterns. […] Damage to the nerves of your digestive system can cause symptoms such as bloating, fullness, and nausea, constipation, diarrhea, especially at night, diarrhea alternating with constipation, fecal incontinence, problems swallowing, and vomiting. […] Autonomic neuropathy may also cause gastroparesis. […] Damage to the nerves of your bladder may make it hard to know when you need to urinate and when your bladder is empty.

• #16 Autonomic neuropathy – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/autonomic-neuropathy/symptoms-causes/syc-20369829

  Autonomic neuropathy occurs when there is damage to the nerves that control automatic body functions. It can affect blood pressure, temperature control, digestion, bladder function and even sexual function. […] Signs and symptoms of autonomic neuropathy depend on which nerves are damaged. They might include: Dizziness and fainting when standing, caused by a sudden drop in blood pressure. Urinary problems, such as difficulty starting urination, loss of bladder control, difficulty sensing a full bladder and inability to completely empty the bladder. Not being able to completely empty the bladder can lead to urinary tract infections. Sexual difficulties, including problems achieving or maintaining an erection (erectile dysfunction) or ejaculation problems. In women, problems include vaginal dryness, low libido and difficulty reaching orgasm. Difficulty digesting food, such as feeling full after a few bites of food, loss of appetite, diarrhea, constipation, abdominal bloating, nausea, vomiting, difficulty swallowing and heartburn. These problems are all due to changes in digestive function. Inability to recognize low blood sugar (hypoglycemia), because the warning signals, such as getting shaky, aren’t there. Sweating problems, such as sweating too much or too little. These problems affect the ability to regulate body temperature. Sluggish pupil reaction, making it difficult to adjust from light to dark and seeing well when driving at night. Exercise intolerance, which can occur if your heart rate stays the same instead of adjusting to your activity level.

• #17 Autonomic Neuropathy – NIDDK

  https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/nerve-damage-diabetic-neuropathies/autonomic-neuropathy

  Autonomic neuropathy can lead to problems with your heart rate and blood pressure. […] The symptoms of autonomic neuropathy depend on which of your body’s functions are affected. […] Damage to the nerves that control your heart rate and blood pressure may make these nerves respond more slowly to a change in your body’s position, stress, physical activity, sleep, and breathing patterns. […] Damage to the nerves of your digestive system can cause symptoms such as bloating, fullness, and nausea, constipation, diarrhea, especially at night, diarrhea alternating with constipation, fecal incontinence, problems swallowing, and vomiting. […] Autonomic neuropathy may also cause gastroparesis. […] Damage to the nerves of your bladder may make it hard to know when you need to urinate and when your bladder is empty.

• #18

  https://link.springer.com/article/10.1007/s00125-015-3828-9

  The overlap between symptom complexes is substantial and in clinical practice the treatment options are more or less the same as for the functional GI disorders. […] The most feared and an often maltreated symptom of autonomic neuropathy is abdominal pain. […] Treating gastrointestinal autonomic neuropathy is a challenge. In diabetes, metabolic control is, and will continue to be, the most important therapeutic aim in order to decrease the risk for the development of GI complications and to reduce the acute effects of hyperglycaemia on GI function.

• #19 Autonomic Neuropathy – NIDDK

  https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/nerve-damage-diabetic-neuropathies/autonomic-neuropathy

  Autonomic neuropathy can lead to problems with your heart rate and blood pressure. […] The symptoms of autonomic neuropathy depend on which of your body’s functions are affected. […] Damage to the nerves that control your heart rate and blood pressure may make these nerves respond more slowly to a change in your body’s position, stress, physical activity, sleep, and breathing patterns. […] Damage to the nerves of your digestive system can cause symptoms such as bloating, fullness, and nausea, constipation, diarrhea, especially at night, diarrhea alternating with constipation, fecal incontinence, problems swallowing, and vomiting. […] Autonomic neuropathy may also cause gastroparesis. […] Damage to the nerves of your bladder may make it hard to know when you need to urinate and when your bladder is empty.

• #20 Autonomic neuropathy – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/autonomic-neuropathy/symptoms-causes/syc-20369829

  Autonomic neuropathy occurs when there is damage to the nerves that control automatic body functions. It can affect blood pressure, temperature control, digestion, bladder function and even sexual function. […] Signs and symptoms of autonomic neuropathy depend on which nerves are damaged. They might include: Dizziness and fainting when standing, caused by a sudden drop in blood pressure. Urinary problems, such as difficulty starting urination, loss of bladder control, difficulty sensing a full bladder and inability to completely empty the bladder. Not being able to completely empty the bladder can lead to urinary tract infections. Sexual difficulties, including problems achieving or maintaining an erection (erectile dysfunction) or ejaculation problems. In women, problems include vaginal dryness, low libido and difficulty reaching orgasm. Difficulty digesting food, such as feeling full after a few bites of food, loss of appetite, diarrhea, constipation, abdominal bloating, nausea, vomiting, difficulty swallowing and heartburn. These problems are all due to changes in digestive function. Inability to recognize low blood sugar (hypoglycemia), because the warning signals, such as getting shaky, aren’t there. Sweating problems, such as sweating too much or too little. These problems affect the ability to regulate body temperature. Sluggish pupil reaction, making it difficult to adjust from light to dark and seeing well when driving at night. Exercise intolerance, which can occur if your heart rate stays the same instead of adjusting to your activity level.

• #21 Autonomic neuropathy – Wikipedia

  https://en.wikipedia.org/wiki/Autonomic_neuropathy

  Autonomic neuropathy (AN or AAN) is a form of polyneuropathy that affects the non-voluntary, non-sensory nervous system (i.e., the autonomic nervous system), affecting mostly the internal organs such as the bladder muscles, the cardiovascular system, the digestive tract, and the genital organs. […] The signs and symptoms of autonomic neuropathy include the following: […] Urinary bladder conditions: urinary incontinence or urinary retention which happens due to the uncoordinated contraction of the bladder. […] Gastrointestinal tract: dysphagia, abdominal pain, nausea, vomiting, malabsorption, fecal incontinence, gastroparesis, diarrhea, constipation […] Cardiovascular system: disturbances of heart rate (tachycardia, bradycardia), orthostatic hypotension, inadequate increase of heart rate on exertion

• #22 Autonomic neuropathy – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/autonomic-neuropathy/symptoms-causes/syc-20369829

  Autonomic neuropathy occurs when there is damage to the nerves that control automatic body functions. It can affect blood pressure, temperature control, digestion, bladder function and even sexual function. […] Signs and symptoms of autonomic neuropathy depend on which nerves are damaged. They might include: Dizziness and fainting when standing, caused by a sudden drop in blood pressure. Urinary problems, such as difficulty starting urination, loss of bladder control, difficulty sensing a full bladder and inability to completely empty the bladder. Not being able to completely empty the bladder can lead to urinary tract infections. Sexual difficulties, including problems achieving or maintaining an erection (erectile dysfunction) or ejaculation problems. In women, problems include vaginal dryness, low libido and difficulty reaching orgasm. Difficulty digesting food, such as feeling full after a few bites of food, loss of appetite, diarrhea, constipation, abdominal bloating, nausea, vomiting, difficulty swallowing and heartburn. These problems are all due to changes in digestive function. Inability to recognize low blood sugar (hypoglycemia), because the warning signals, such as getting shaky, aren’t there. Sweating problems, such as sweating too much or too little. These problems affect the ability to regulate body temperature. Sluggish pupil reaction, making it difficult to adjust from light to dark and seeing well when driving at night. Exercise intolerance, which can occur if your heart rate stays the same instead of adjusting to your activity level.

• #23 Autonomic Neuropathy – NIDDK

  https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/nerve-damage-diabetic-neuropathies/autonomic-neuropathy

  In men, damage to nerves in the sex organs may prevent the penis from getting firm when a man wants to have sex. […] In women, damage to the nerves in the sex organs can prevent the vagina from getting wet when a woman wants to have sex. […] Damage to the nerves that control your sweat glands may cause you to sweat a lot at night or while eating. […] Damage to the nerves in your pupils may make them slow to respond to changes in light and darkness. […] Autonomic neuropathy can cause hypoglycemia unawareness, meaning that you don’t feel the symptoms of low blood glucose.

• #24 Autonomic neuropathy – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/autonomic-neuropathy/symptoms-causes/syc-20369829

  Autonomic neuropathy occurs when there is damage to the nerves that control automatic body functions. It can affect blood pressure, temperature control, digestion, bladder function and even sexual function. […] Signs and symptoms of autonomic neuropathy depend on which nerves are damaged. They might include: Dizziness and fainting when standing, caused by a sudden drop in blood pressure. Urinary problems, such as difficulty starting urination, loss of bladder control, difficulty sensing a full bladder and inability to completely empty the bladder. Not being able to completely empty the bladder can lead to urinary tract infections. Sexual difficulties, including problems achieving or maintaining an erection (erectile dysfunction) or ejaculation problems. In women, problems include vaginal dryness, low libido and difficulty reaching orgasm. Difficulty digesting food, such as feeling full after a few bites of food, loss of appetite, diarrhea, constipation, abdominal bloating, nausea, vomiting, difficulty swallowing and heartburn. These problems are all due to changes in digestive function. Inability to recognize low blood sugar (hypoglycemia), because the warning signals, such as getting shaky, aren’t there. Sweating problems, such as sweating too much or too little. These problems affect the ability to regulate body temperature. Sluggish pupil reaction, making it difficult to adjust from light to dark and seeing well when driving at night. Exercise intolerance, which can occur if your heart rate stays the same instead of adjusting to your activity level.

• #25 Autonomic Neuropathy – NIDDK

  https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/nerve-damage-diabetic-neuropathies/autonomic-neuropathy

  In men, damage to nerves in the sex organs may prevent the penis from getting firm when a man wants to have sex. […] In women, damage to the nerves in the sex organs can prevent the vagina from getting wet when a woman wants to have sex. […] Damage to the nerves that control your sweat glands may cause you to sweat a lot at night or while eating. […] Damage to the nerves in your pupils may make them slow to respond to changes in light and darkness. […] Autonomic neuropathy can cause hypoglycemia unawareness, meaning that you don’t feel the symptoms of low blood glucose.

• #26 Autonomic neuropathy – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/autonomic-neuropathy/symptoms-causes/syc-20369829

  Autonomic neuropathy occurs when there is damage to the nerves that control automatic body functions. It can affect blood pressure, temperature control, digestion, bladder function and even sexual function. […] Signs and symptoms of autonomic neuropathy depend on which nerves are damaged. They might include: Dizziness and fainting when standing, caused by a sudden drop in blood pressure. Urinary problems, such as difficulty starting urination, loss of bladder control, difficulty sensing a full bladder and inability to completely empty the bladder. Not being able to completely empty the bladder can lead to urinary tract infections. Sexual difficulties, including problems achieving or maintaining an erection (erectile dysfunction) or ejaculation problems. In women, problems include vaginal dryness, low libido and difficulty reaching orgasm. Difficulty digesting food, such as feeling full after a few bites of food, loss of appetite, diarrhea, constipation, abdominal bloating, nausea, vomiting, difficulty swallowing and heartburn. These problems are all due to changes in digestive function. Inability to recognize low blood sugar (hypoglycemia), because the warning signals, such as getting shaky, aren’t there. Sweating problems, such as sweating too much or too little. These problems affect the ability to regulate body temperature. Sluggish pupil reaction, making it difficult to adjust from light to dark and seeing well when driving at night. Exercise intolerance, which can occur if your heart rate stays the same instead of adjusting to your activity level.

• #27 Autonomic Neuropathy: Causes, Diagnosis, & Prevention

  https://www.healthline.com/health/autonomic-neuropathy

  The symptoms of AN that affect your heart and blood vessels can include: dizziness when rising or standing, fainting, difficulty breathing during exercise, rapid heart rate at rest, heart attack without any warning signs. […] The symptoms of AN that affect your eyes can include slow pupil adjustment from dark to light and difficulty driving at night. […] The symptoms of AN that affect your sweat glands can include dry skin on your feet and excessive sweating or lack of sweating. […] Other symptoms of AN can include unexplained weight loss and low blood glucose without warning signals, such as shakiness. […] Your outlook varies based on the cause of your nerve damage and how well it can be treated. In some cases, the nerves can repair themselves. In others, symptoms remain the same or even worsen despite treatment.

• #28 Autonomic neuropathy – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/autonomic-neuropathy/symptoms-causes/syc-20369829

  Autonomic neuropathy occurs when there is damage to the nerves that control automatic body functions. It can affect blood pressure, temperature control, digestion, bladder function and even sexual function. […] Signs and symptoms of autonomic neuropathy depend on which nerves are damaged. They might include: Dizziness and fainting when standing, caused by a sudden drop in blood pressure. Urinary problems, such as difficulty starting urination, loss of bladder control, difficulty sensing a full bladder and inability to completely empty the bladder. Not being able to completely empty the bladder can lead to urinary tract infections. Sexual difficulties, including problems achieving or maintaining an erection (erectile dysfunction) or ejaculation problems. In women, problems include vaginal dryness, low libido and difficulty reaching orgasm. Difficulty digesting food, such as feeling full after a few bites of food, loss of appetite, diarrhea, constipation, abdominal bloating, nausea, vomiting, difficulty swallowing and heartburn. These problems are all due to changes in digestive function. Inability to recognize low blood sugar (hypoglycemia), because the warning signals, such as getting shaky, aren’t there. Sweating problems, such as sweating too much or too little. These problems affect the ability to regulate body temperature. Sluggish pupil reaction, making it difficult to adjust from light to dark and seeing well when driving at night. Exercise intolerance, which can occur if your heart rate stays the same instead of adjusting to your activity level.

• #29 Autonomic Neuropathy – NIDDK

  https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/nerve-damage-diabetic-neuropathies/autonomic-neuropathy

  In men, damage to nerves in the sex organs may prevent the penis from getting firm when a man wants to have sex. […] In women, damage to the nerves in the sex organs can prevent the vagina from getting wet when a woman wants to have sex. […] Damage to the nerves that control your sweat glands may cause you to sweat a lot at night or while eating. […] Damage to the nerves in your pupils may make them slow to respond to changes in light and darkness. […] Autonomic neuropathy can cause hypoglycemia unawareness, meaning that you don’t feel the symptoms of low blood glucose.

• #30 Autonomic neuropathy – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/autonomic-neuropathy/symptoms-causes/syc-20369829

  Autonomic neuropathy occurs when there is damage to the nerves that control automatic body functions. It can affect blood pressure, temperature control, digestion, bladder function and even sexual function. […] Signs and symptoms of autonomic neuropathy depend on which nerves are damaged. They might include: Dizziness and fainting when standing, caused by a sudden drop in blood pressure. Urinary problems, such as difficulty starting urination, loss of bladder control, difficulty sensing a full bladder and inability to completely empty the bladder. Not being able to completely empty the bladder can lead to urinary tract infections. Sexual difficulties, including problems achieving or maintaining an erection (erectile dysfunction) or ejaculation problems. In women, problems include vaginal dryness, low libido and difficulty reaching orgasm. Difficulty digesting food, such as feeling full after a few bites of food, loss of appetite, diarrhea, constipation, abdominal bloating, nausea, vomiting, difficulty swallowing and heartburn. These problems are all due to changes in digestive function. Inability to recognize low blood sugar (hypoglycemia), because the warning signals, such as getting shaky, aren’t there. Sweating problems, such as sweating too much or too little. These problems affect the ability to regulate body temperature. Sluggish pupil reaction, making it difficult to adjust from light to dark and seeing well when driving at night. Exercise intolerance, which can occur if your heart rate stays the same instead of adjusting to your activity level.

• #31 Autonomic Neuropathy – NIDDK

  https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/nerve-damage-diabetic-neuropathies/autonomic-neuropathy

  In men, damage to nerves in the sex organs may prevent the penis from getting firm when a man wants to have sex. […] In women, damage to the nerves in the sex organs can prevent the vagina from getting wet when a woman wants to have sex. […] Damage to the nerves that control your sweat glands may cause you to sweat a lot at night or while eating. […] Damage to the nerves in your pupils may make them slow to respond to changes in light and darkness. […] Autonomic neuropathy can cause hypoglycemia unawareness, meaning that you don’t feel the symptoms of low blood glucose.

• #32 Autonomic neuropathy – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/autonomic-neuropathy/symptoms-causes/syc-20369829

  Autonomic neuropathy occurs when there is damage to the nerves that control automatic body functions. It can affect blood pressure, temperature control, digestion, bladder function and even sexual function. […] Signs and symptoms of autonomic neuropathy depend on which nerves are damaged. They might include: Dizziness and fainting when standing, caused by a sudden drop in blood pressure. Urinary problems, such as difficulty starting urination, loss of bladder control, difficulty sensing a full bladder and inability to completely empty the bladder. Not being able to completely empty the bladder can lead to urinary tract infections. Sexual difficulties, including problems achieving or maintaining an erection (erectile dysfunction) or ejaculation problems. In women, problems include vaginal dryness, low libido and difficulty reaching orgasm. Difficulty digesting food, such as feeling full after a few bites of food, loss of appetite, diarrhea, constipation, abdominal bloating, nausea, vomiting, difficulty swallowing and heartburn. These problems are all due to changes in digestive function. Inability to recognize low blood sugar (hypoglycemia), because the warning signals, such as getting shaky, aren’t there. Sweating problems, such as sweating too much or too little. These problems affect the ability to regulate body temperature. Sluggish pupil reaction, making it difficult to adjust from light to dark and seeing well when driving at night. Exercise intolerance, which can occur if your heart rate stays the same instead of adjusting to your activity level.

• #33 Autonomic Neuropathy Clinical Presentation: History, Physical, Causes

  https://emedicine.medscape.com/article/1173756-clinical

  Most of the primary autonomic disorders are chronic in nature, with symptoms often initiating in an insidious fashion. However, in acute autonomic neuropathies, the onset can be dramatic with presentation as a generalized dysautonomia. In general, patients present with symptoms of both sympathetic and parasympathetic dysfunction, with or without symptoms of somatic nervous system dysfunction. […] Orthostatic hypotension is often the first recognized symptom and is typically the most disabling. […] However, other autonomic symptoms can occur before syncope, and these include impotence or ejaculatory dysfunction, decreased sweating, and urinary incontinence. […] For example, in Sj gren syndrome, dry mouth and eyes along with anhidrosis are typically the initial symptoms in affected patients. […] Many complications of autonomic neuropathy exist, as described above. The most severe are cardiac arrest, cardiac dysrhythmia, blood pressure fluctuations, and risk of cerebral and cardiac ischemia.

• #34 Autonomic Neuropathy Progression – Acibadem Health Point – ACIBADEM Hospitals – Acibadem Health Group

  https://www.acibademhealthpoint.com/autonomic-neuropathy-progression/

  Autonomic neuropathy affects the autonomic nervous system. This system controls things we don’t think about, like heart rate and digestion. When it’s not working right, it causes problems that make everyday tasks hard. […] How autonomic neuropathy gets worse can change a lot. It depends on the cause, which nerves are affected, and the treatment. For people with chronic conditions, knowing how it gets worse is important. It helps them manage their symptoms better and live better lives. Early action is key to fighting the effects of this condition. […] Autonomic neuropathy gets worse over time. It has different neuropathy stages that show how nerve damage gets worse. Knowing these stages helps manage the condition better and lessen its effects on daily life. […] In the early stages, symptoms are often mild and easy to overlook. People might feel a bit off, with issues like blood pressure or digestion problems. It’s important to notice these early signs to slow down nerve damage.

• #35 Autonomic Neuropathy Progression – Acibadem Health Point – ACIBADEM Hospitals – Acibadem Health Group

  https://www.acibademhealthpoint.com/autonomic-neuropathy-progression/

  Autonomic neuropathy affects the autonomic nervous system. This system controls things we don’t think about, like heart rate and digestion. When it’s not working right, it causes problems that make everyday tasks hard. […] How autonomic neuropathy gets worse can change a lot. It depends on the cause, which nerves are affected, and the treatment. For people with chronic conditions, knowing how it gets worse is important. It helps them manage their symptoms better and live better lives. Early action is key to fighting the effects of this condition. […] Autonomic neuropathy gets worse over time. It has different neuropathy stages that show how nerve damage gets worse. Knowing these stages helps manage the condition better and lessen its effects on daily life. […] In the early stages, symptoms are often mild and easy to overlook. People might feel a bit off, with issues like blood pressure or digestion problems. It’s important to notice these early signs to slow down nerve damage.

• #36 Neuropathy: Symptoms & Causes | NewYork-Presbyterian

  https://www.nyp.org/neuro/neuromuscular-disorders/neuropathy

  Autonomic neuropathy may affect various organs and related functioning, including: […] Autonomic neuropathy symptoms may include: Blood pressure changes, Heart rate changes, Sweating, Bowel and urinary incontinence, Sexual dysfunction, Dizziness and fainting, Dry mouth and eyes. […] As neuropathy develops, there are several stages of progression, ranging from early-onset to late-stage neuropathy. […] Early stage: Symptoms are very mild and can be self-managed. This is the best time to seek medical treatment to protect and preserve your peripheral nerve health. […] Middle stages: Symptoms are more pronounced and painful. Some individuals may have trouble sleeping. […] Later stages: Symptoms have progressed and may include muscle weakness, pain, and numbness. There is also a higher risk of injury and related complications due to increased nerve damage.

• #37 What Is Autonomic Neuropathy?

  https://www.icliniq.com/articles/neurological-health/autonomic-neuropathy

  Other signs and symptoms could include: Sweating excessively or insufficiently. Heat intolerance develops as a result of physical exertion and exercise. Erection problems in males, as well as vaginal dryness and orgasm issues in females. One eye has a small pupil. Weight loss without putting any effort. […] The rate of progression of autonomic neuropathy is indicated by testing of their autonomic systems, which showed high heart rate variability as their autonomics continued to fail. Diabetic autonomic neuropathy (DAN) and cardiac autonomic neuropathy (CAN), which have a 50 % five-year death risk, are the most advanced autonomic test patterns indicating poor parasympathetic function. The danger of sudden cardiac death is increased because the person’s autonomic functions are severely inhibited at times, such as when unconscious from sedation.

• #38 Stages of Autonomic Dysfunction – Nemechek Autonomic Medicine

  https://www.nemechekconsultativemedicine.com/stages/

  As Autonomic function declines and inflammation rises their symptoms may also be mental or emotional in nature. People have a harder time recovering from trauma and may suffer from anxiety, panic attacks, depression, post-partum, and PTSD. […] Multiple systems in the body malfunction and people feel increasingly worse. Blood pressure or blood sugars get harder to regulate even with medications, and people have poor responses to other medical therapies. […] As their Autonomics continue to malfunction, Autonomic testing reveals increased Low HRV (Heart Rate Variability). The most advanced Autonomic test patterns of weak Parasympathetic function are Diabetic Autonomic Neuropathy (DAN), and Cardiac Autonomic Neuropathy (CAN) which has a 50% mortality rate within 5 years.

• #39 Peripheral Neuropathy: What It Is, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/14737-peripheral-neuropathy

  Sexual dysfunction. Your autonomic nervous system controls sexual arousal. Thats why autonomic problems can cause sexual dysfunction. […] Other symptoms. Autonomic changes from peripheral neuropathy can also cause skin color changes, swelling, changes in the pupils of the eyes and blurry vision. […] How quickly does peripheral neuropathy develop? […] How peripheral neuropathy develops, particularly the timeline of its progress, depends very much on what causes it. Injuries can cause it to develop instantaneously or within minutes or hours. Some toxic and inflammation-based forms of peripheral neuropathy may develop rapidly over days or weeks, while most other conditions take months, years or even decades to develop.

• #40 Autonomic Neuropathy: Background, Pathophysiology, Inherited Autonomic Neuropathies

  https://emedicine.medscape.com/article/1173756-overview

  Autonomic neuropathies are a collection of syndromes and diseases affecting the autonomic neurons, either parasympathetic or sympathetic, or both. […] The autonomic nervous system modulates numerous body functions; therefore, autonomic dysfunction may manifest with numerous clinical phenotypes and various laboratory and neurophysiologic abnormalities. […] In some patients, the degree of autonomic dysfunction may be subclinical or clinically irrelevant; in others, symptoms may be disabling. […] Several clinically important features of autonomic neuropathies are treatable; therefore, the physician must be alert to these features. […] The prognosis depends on the particular syndrome causing autonomic neuropathy. In many cases, the course is gradually progressive in nature. […] In specific cases, the prognosis may be improved by controlling diabetes mellitus, limiting alcohol intake, and treating correctable syndromes or diseases as applicable to prevent progression. […] In the case of acute autonomic neuropathies, such as acute pandysautonomia and GBS, the prognosis is often good after resolution of the acute illness.

• #41 Autonomic Neuropathy: Background, Pathophysiology, Inherited Autonomic Neuropathies

  https://emedicine.medscape.com/article/1173756-overview

  Autonomic neuropathies are a collection of syndromes and diseases affecting the autonomic neurons, either parasympathetic or sympathetic, or both. […] The autonomic nervous system modulates numerous body functions; therefore, autonomic dysfunction may manifest with numerous clinical phenotypes and various laboratory and neurophysiologic abnormalities. […] In some patients, the degree of autonomic dysfunction may be subclinical or clinically irrelevant; in others, symptoms may be disabling. […] Several clinically important features of autonomic neuropathies are treatable; therefore, the physician must be alert to these features. […] The prognosis depends on the particular syndrome causing autonomic neuropathy. In many cases, the course is gradually progressive in nature. […] In specific cases, the prognosis may be improved by controlling diabetes mellitus, limiting alcohol intake, and treating correctable syndromes or diseases as applicable to prevent progression. […] In the case of acute autonomic neuropathies, such as acute pandysautonomia and GBS, the prognosis is often good after resolution of the acute illness.

• #42 Small Fiber Neuropathy Overview – Therapath Neuropathology

  https://therapath.com/small-fiber-neuropathy-overview/

  Symptoms of autonomic small fiber neuropathy include abnormal sweating or temperature regulation, lightheadedness or fainting when standing up from hypotension or tachycardia, gastroparesis with bloating and constipation or diarrhea, incomplete bladder emptying or difficulty initiating a stream, sexual dysfunction from hypo or hypersensitivity, dryness and thinning of the skin, hair loss in the legs, and ridged or brittle nails. […] In some cases, a progressive neuropathy that affects both the small and large nerve fibers can first present as small fiber neuropathies before progressing to involve the large fibers, at which point it can also cause electrodiagnostic abnormalities. […] Progression of the underlying neuropathy can be evaluated by repeating the biopsy and monitoring the ENFD.

• #43 Autonomic Neuropathy: Background, Pathophysiology, Inherited Autonomic Neuropathies

  https://emedicine.medscape.com/article/1173756-overview

  Autonomic neuropathies are a collection of syndromes and diseases affecting the autonomic neurons, either parasympathetic or sympathetic, or both. […] The autonomic nervous system modulates numerous body functions; therefore, autonomic dysfunction may manifest with numerous clinical phenotypes and various laboratory and neurophysiologic abnormalities. […] In some patients, the degree of autonomic dysfunction may be subclinical or clinically irrelevant; in others, symptoms may be disabling. […] Several clinically important features of autonomic neuropathies are treatable; therefore, the physician must be alert to these features. […] The prognosis depends on the particular syndrome causing autonomic neuropathy. In many cases, the course is gradually progressive in nature. […] In specific cases, the prognosis may be improved by controlling diabetes mellitus, limiting alcohol intake, and treating correctable syndromes or diseases as applicable to prevent progression. […] In the case of acute autonomic neuropathies, such as acute pandysautonomia and GBS, the prognosis is often good after resolution of the acute illness.

• #44 Dysautonomia: What It Is, Symptoms, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/6004-dysautonomia

  Dysautonomia symptoms can affect many body systems, and they may look different depending on the system they affect, like: […] Symptoms of dysautonomia can affect automatic body processes throughout your body. […] These include, but aren’t limited to, chest pain, mood swings, fainting, fatigue and dizziness. […] Dysautonomia can look very different from person to person, even among family members. Your symptoms may be totally different from someone else’s. Your symptoms and how they impact your life can also vary widely. […] Some forms of dysautonomia may be temporary, but it’s usually a lifelong condition. […] Dysautonomia is an unpredictable condition. Some people may experience frequent symptoms. Others may go months or even years without any. It’s difficult to predict what your life will look like living with dysautonomia, but your healthcare provider can help you understand what’s possible or likely and what you can do to limit the impact on your life.

• #45 Autonomic Neuropathy: Background, Pathophysiology, Inherited Autonomic Neuropathies

  https://emedicine.medscape.com/article/1173756-overview

  Autonomic neuropathies are a collection of syndromes and diseases affecting the autonomic neurons, either parasympathetic or sympathetic, or both. […] The autonomic nervous system modulates numerous body functions; therefore, autonomic dysfunction may manifest with numerous clinical phenotypes and various laboratory and neurophysiologic abnormalities. […] In some patients, the degree of autonomic dysfunction may be subclinical or clinically irrelevant; in others, symptoms may be disabling. […] Several clinically important features of autonomic neuropathies are treatable; therefore, the physician must be alert to these features. […] The prognosis depends on the particular syndrome causing autonomic neuropathy. In many cases, the course is gradually progressive in nature. […] In specific cases, the prognosis may be improved by controlling diabetes mellitus, limiting alcohol intake, and treating correctable syndromes or diseases as applicable to prevent progression. […] In the case of acute autonomic neuropathies, such as acute pandysautonomia and GBS, the prognosis is often good after resolution of the acute illness.

• #46 Dysautonomia: What It Is, Symptoms, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/6004-dysautonomia

  Depending on the cause, dysautonomia may be a minor concern. But some forms or causes especially chronic or incurable conditions may have larger impacts. In severe cases, the symptoms may affect your ability to work or participate in activities you enjoy. This condition may also cause deadly complications.

• #47 Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5763036/

  Cardiac autonomic neuropathy (CAN) is a serious complication of diabetes mellitus (DM) that is strongly associated with approximately five-fold increased risk of cardiovascular mortality. CAN manifests in a spectrum of things, ranging from resting tachycardia and fixed heart rate (HR) to development of silent myocardial infarction. […] Symptomatic manifestations of CAN include sinus tachycardia, exercise intolerance, orthostatic hypotension (OH), abnormal blood pressure (BP) regulation, dizziness, presyncope and syncope, intraoperative cardiovascular instability, asymptomatic myocardial ischemia and infarction. […] Although it is common complication, the significance of CAN has not been fully appreciated and there are no unified treatment algorithms for today. Treatment is based on early diagnosis, life style changes, optimization of glycemic control and management of cardiovascular risk factors.

• #48 Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5763036/

  Cardiac autonomic neuropathy (CAN) is a serious complication of diabetes mellitus (DM) that is strongly associated with approximately five-fold increased risk of cardiovascular mortality. CAN manifests in a spectrum of things, ranging from resting tachycardia and fixed heart rate (HR) to development of silent myocardial infarction. […] Symptomatic manifestations of CAN include sinus tachycardia, exercise intolerance, orthostatic hypotension (OH), abnormal blood pressure (BP) regulation, dizziness, presyncope and syncope, intraoperative cardiovascular instability, asymptomatic myocardial ischemia and infarction. […] Although it is common complication, the significance of CAN has not been fully appreciated and there are no unified treatment algorithms for today. Treatment is based on early diagnosis, life style changes, optimization of glycemic control and management of cardiovascular risk factors.

• #49 What Is Cardiovascular Autonomic Neuropathy?

  https://www.verywellhealth.com/cardiovascular-autonomic-neuropathy-5223358

  CAN symptoms affect a person’s quality of life. They commonly include the following: Light-headedness or dizziness, especially with standing, Palpitations, Racing heart, Fainting, Fatigue, Exercise intolerance. […] Many symptoms of CAN occur or worsen when changing position from lying or sitting to standing. Symptoms such as light-headedness and vision disturbance upon standing are known as orthostatic intolerance. […] This condition can result in symptoms that affect daily life, such as fatigue, heart racing, orthostatic intolerance, and difficulty exercising.

• #50 What Is Cardiovascular Autonomic Neuropathy?

  https://www.verywellhealth.com/cardiovascular-autonomic-neuropathy-5223358

  CAN symptoms affect a person’s quality of life. They commonly include the following: Light-headedness or dizziness, especially with standing, Palpitations, Racing heart, Fainting, Fatigue, Exercise intolerance. […] Many symptoms of CAN occur or worsen when changing position from lying or sitting to standing. Symptoms such as light-headedness and vision disturbance upon standing are known as orthostatic intolerance. […] This condition can result in symptoms that affect daily life, such as fatigue, heart racing, orthostatic intolerance, and difficulty exercising.

• #51

  https://link.springer.com/article/10.1007/s00125-015-3828-9

  The symptoms caused by gastrointestinal autonomic neuropathy in diabetes mellitus is important to highlight since it affects a large proportion of people with diabetes, regardless of whether this is type 1 or type 2. […] Gastroparesis and general signs of bowel dysfunction, such as constipation, diarrhoea and abdominal pain are most often encountered and involve both pharmacological and non-pharmacological treatment options. […] All parts of the GI tract might be affected by a GI autonomic neuropathy, but those most commonly encountered are related to stomach and bowel dysfunction. […] If an autonomic GI neuropathy is suspected, GI function tests are performed, and studies have suggested that the results of these need to be interpreted with some caution in terms of assessing any potential association between the observed dysfunction and the specific GI symptoms.

• #52

  https://link.springer.com/article/10.1007/s00125-015-3828-9

  The symptoms caused by gastrointestinal autonomic neuropathy in diabetes mellitus is important to highlight since it affects a large proportion of people with diabetes, regardless of whether this is type 1 or type 2. […] Gastroparesis and general signs of bowel dysfunction, such as constipation, diarrhoea and abdominal pain are most often encountered and involve both pharmacological and non-pharmacological treatment options. […] All parts of the GI tract might be affected by a GI autonomic neuropathy, but those most commonly encountered are related to stomach and bowel dysfunction. […] If an autonomic GI neuropathy is suspected, GI function tests are performed, and studies have suggested that the results of these need to be interpreted with some caution in terms of assessing any potential association between the observed dysfunction and the specific GI symptoms.

• #53

  https://link.springer.com/article/10.1007/s00125-015-3828-9

  The symptoms caused by gastrointestinal autonomic neuropathy in diabetes mellitus is important to highlight since it affects a large proportion of people with diabetes, regardless of whether this is type 1 or type 2. […] Gastroparesis and general signs of bowel dysfunction, such as constipation, diarrhoea and abdominal pain are most often encountered and involve both pharmacological and non-pharmacological treatment options. […] All parts of the GI tract might be affected by a GI autonomic neuropathy, but those most commonly encountered are related to stomach and bowel dysfunction. […] If an autonomic GI neuropathy is suspected, GI function tests are performed, and studies have suggested that the results of these need to be interpreted with some caution in terms of assessing any potential association between the observed dysfunction and the specific GI symptoms.

• #54 All You Need to Know About Autonomic Neuropathy

  https://lonestarneurology.net/peripheral-neuropathy/autonomic-neuropathy-symptoms-causes/

  Autonomic neuropathy can have a significant impact on an individuals quality of life. As it can affect their ability to carry out daily activities and lead to discomfort and pain. It can also lead to serious complications, such as: heart failure; kidney damage; gastrointestinal bleeding. Thus, early recognition and treatment of the condition are crucial to prevent it further. It may help improve outcomes. The symptoms of autonomic neuropathy can vary depending on: the nerves affected; the underlying cause. Common symptoms include: dizziness; fainting; irregular heartbeat; difficulty swallowing; constipation or diarrhea; bladder problems. The most important symptom is low blood pressure. Men may also have difficulty achieving and maintaining an erection (erectile dysfunction). Some patients bladders become overactive. It may cause them to urinate involuntarily (urinary incontinence). Others have difficulty urinating (urinary retention) because their bladder is inactive. Your organism may delay gastric emptying (gastroparesis). This person may feel full too soon when eating and may vomit. Severe constipation may occur. In general, the main symptoms of autonomic dysfunction are as the following: digestive and urinary symptoms; cardiovascular symptoms; sexual dysfunction; sweating and temperature regulation; eye and vision problems; nerve pain. If somatic nerves are also damaged, the patient may lose sensation. They also can feel tingling in the hands and feet and develop muscle weakness. Sometimes there is pathological hypersensitivity during autonomic disorder when: a slight touch to a certain body area causes severe pain; the impact of the disease is significant, and there is no pain. Pain sensitivity can completely disappear. So, for example, you will not notice a small injury or a cut will. But due to impaired innervation, such a wound takes a long time to heal and often develops into a trophic ulcer. In severe cases, patients may notice: the appearance of vegetative disorders; deterioration of the blood supply to the skin. It looks pale, dry, and atrophic. Autonomic neuropathy can cause various digestive symptoms, such as: bloating; constipation; diarrhea; nausea; vomiting; loss of appetite. Autonomic neuropathy can affect the bladder, causing: urinary incontinence; retention; urgency. These symptoms occur due to damage to the nerves that control the bladder. It results in an inability to control urine flow. People with the autonomic disorder may experience frequent urinary tract infections. This is due to incomplete emptying of the bladder. Autonomic neuropathy can affect the heart, causing: irregular heartbeat; low blood pressure upon standing (orthostatic hypotension); rapid heartbeat. These symptoms occur due to damage to the nerves that regulate heart rate and blood pressure. Individuals with this disorder may experience fainting spells or dizziness when standing up. The disease can affect sexual function. The following symptoms can be: erectile dysfunction in men; vaginal dryness or difficulty reaching orgasm in women. It occurs due to nerve damage which controls sexual arousal and response. Individuals with autonomic nervous dysfunction may also experience decreased libido or sexual desire. Neuropathy can affect the bodys ability to sweat and regulate temperature. So the person can experience symptoms such as: excessive sweating; a lack of sweat; intolerance to hot or cold temperatures. This disorder can cause eye problems such as: blurry vision; double vision; difficulty adjusting to changes in light. Autonomic neuropathy symptoms can cause nerve pain in the feet and hands. Patients may describe it as: burning; tingling; numbness.

• #55 All You Need to Know About Autonomic Neuropathy

  https://lonestarneurology.net/peripheral-neuropathy/autonomic-neuropathy-symptoms-causes/

  Autonomic neuropathy can have a significant impact on an individuals quality of life. As it can affect their ability to carry out daily activities and lead to discomfort and pain. It can also lead to serious complications, such as: heart failure; kidney damage; gastrointestinal bleeding. Thus, early recognition and treatment of the condition are crucial to prevent it further. It may help improve outcomes. The symptoms of autonomic neuropathy can vary depending on: the nerves affected; the underlying cause. Common symptoms include: dizziness; fainting; irregular heartbeat; difficulty swallowing; constipation or diarrhea; bladder problems. The most important symptom is low blood pressure. Men may also have difficulty achieving and maintaining an erection (erectile dysfunction). Some patients bladders become overactive. It may cause them to urinate involuntarily (urinary incontinence). Others have difficulty urinating (urinary retention) because their bladder is inactive. Your organism may delay gastric emptying (gastroparesis). This person may feel full too soon when eating and may vomit. Severe constipation may occur. In general, the main symptoms of autonomic dysfunction are as the following: digestive and urinary symptoms; cardiovascular symptoms; sexual dysfunction; sweating and temperature regulation; eye and vision problems; nerve pain. If somatic nerves are also damaged, the patient may lose sensation. They also can feel tingling in the hands and feet and develop muscle weakness. Sometimes there is pathological hypersensitivity during autonomic disorder when: a slight touch to a certain body area causes severe pain; the impact of the disease is significant, and there is no pain. Pain sensitivity can completely disappear. So, for example, you will not notice a small injury or a cut will. But due to impaired innervation, such a wound takes a long time to heal and often develops into a trophic ulcer. In severe cases, patients may notice: the appearance of vegetative disorders; deterioration of the blood supply to the skin. It looks pale, dry, and atrophic. Autonomic neuropathy can cause various digestive symptoms, such as: bloating; constipation; diarrhea; nausea; vomiting; loss of appetite. Autonomic neuropathy can affect the bladder, causing: urinary incontinence; retention; urgency. These symptoms occur due to damage to the nerves that control the bladder. It results in an inability to control urine flow. People with the autonomic disorder may experience frequent urinary tract infections. This is due to incomplete emptying of the bladder. Autonomic neuropathy can affect the heart, causing: irregular heartbeat; low blood pressure upon standing (orthostatic hypotension); rapid heartbeat. These symptoms occur due to damage to the nerves that regulate heart rate and blood pressure. Individuals with this disorder may experience fainting spells or dizziness when standing up. The disease can affect sexual function. The following symptoms can be: erectile dysfunction in men; vaginal dryness or difficulty reaching orgasm in women. It occurs due to nerve damage which controls sexual arousal and response. Individuals with autonomic nervous dysfunction may also experience decreased libido or sexual desire. Neuropathy can affect the bodys ability to sweat and regulate temperature. So the person can experience symptoms such as: excessive sweating; a lack of sweat; intolerance to hot or cold temperatures. This disorder can cause eye problems such as: blurry vision; double vision; difficulty adjusting to changes in light. Autonomic neuropathy symptoms can cause nerve pain in the feet and hands. Patients may describe it as: burning; tingling; numbness.

• #56 All You Need to Know About Autonomic Neuropathy

  https://lonestarneurology.net/peripheral-neuropathy/autonomic-neuropathy-symptoms-causes/

  Autonomic neuropathy can have a significant impact on an individuals quality of life. As it can affect their ability to carry out daily activities and lead to discomfort and pain. It can also lead to serious complications, such as: heart failure; kidney damage; gastrointestinal bleeding. Thus, early recognition and treatment of the condition are crucial to prevent it further. It may help improve outcomes. The symptoms of autonomic neuropathy can vary depending on: the nerves affected; the underlying cause. Common symptoms include: dizziness; fainting; irregular heartbeat; difficulty swallowing; constipation or diarrhea; bladder problems. The most important symptom is low blood pressure. Men may also have difficulty achieving and maintaining an erection (erectile dysfunction). Some patients bladders become overactive. It may cause them to urinate involuntarily (urinary incontinence). Others have difficulty urinating (urinary retention) because their bladder is inactive. Your organism may delay gastric emptying (gastroparesis). This person may feel full too soon when eating and may vomit. Severe constipation may occur. In general, the main symptoms of autonomic dysfunction are as the following: digestive and urinary symptoms; cardiovascular symptoms; sexual dysfunction; sweating and temperature regulation; eye and vision problems; nerve pain. If somatic nerves are also damaged, the patient may lose sensation. They also can feel tingling in the hands and feet and develop muscle weakness. Sometimes there is pathological hypersensitivity during autonomic disorder when: a slight touch to a certain body area causes severe pain; the impact of the disease is significant, and there is no pain. Pain sensitivity can completely disappear. So, for example, you will not notice a small injury or a cut will. But due to impaired innervation, such a wound takes a long time to heal and often develops into a trophic ulcer. In severe cases, patients may notice: the appearance of vegetative disorders; deterioration of the blood supply to the skin. It looks pale, dry, and atrophic. Autonomic neuropathy can cause various digestive symptoms, such as: bloating; constipation; diarrhea; nausea; vomiting; loss of appetite. Autonomic neuropathy can affect the bladder, causing: urinary incontinence; retention; urgency. These symptoms occur due to damage to the nerves that control the bladder. It results in an inability to control urine flow. People with the autonomic disorder may experience frequent urinary tract infections. This is due to incomplete emptying of the bladder. Autonomic neuropathy can affect the heart, causing: irregular heartbeat; low blood pressure upon standing (orthostatic hypotension); rapid heartbeat. These symptoms occur due to damage to the nerves that regulate heart rate and blood pressure. Individuals with this disorder may experience fainting spells or dizziness when standing up. The disease can affect sexual function. The following symptoms can be: erectile dysfunction in men; vaginal dryness or difficulty reaching orgasm in women. It occurs due to nerve damage which controls sexual arousal and response. Individuals with autonomic nervous dysfunction may also experience decreased libido or sexual desire. Neuropathy can affect the bodys ability to sweat and regulate temperature. So the person can experience symptoms such as: excessive sweating; a lack of sweat; intolerance to hot or cold temperatures. This disorder can cause eye problems such as: blurry vision; double vision; difficulty adjusting to changes in light. Autonomic neuropathy symptoms can cause nerve pain in the feet and hands. Patients may describe it as: burning; tingling; numbness.

• #57 Autonomic neuropathy – UF Health

  https://ufhealth.org/conditions-and-treatments/autonomic-neuropathy

  Autonomic neuropathy is a group of symptoms that occur when there is damage to the nerves that manage normally automatic body functions. These functions include blood pressure, heart rate, sweating, bowel and bladder emptying, and digestion. […] Symptoms vary, depending on the nerves affected. They usually develop slowly over years. […] Early diagnosis and treatment may control symptoms.

• #58 Treatment for Autonomic Dysfunction – Diagnostic and Testing

  https://lonestarneurology.net/peripheral-neuropathy/methods-of-treatment-for-autonomic-dysfunction/

  The severity of autonomic neuropathy can vary depending on: the extent of nerve damage; the conditions underlying cause. […] If you have this disorder, you have to: work closely with your healthcare provider to manage your symptoms; prevent complications. […] You can take medication to manage symptoms like pain, dizziness, or digestive issues. You can effectively manage the symptoms by doing a test for autonomic neuropathy. The changes in blood pressure and heart rate are then measured as the person is tilted upright. […] In severe cases of autonomic dysfunction, IV fluids may be necessary. They really help manage symptoms like: low blood pressure; dehydration. […] In severe cases of autonomic dysfunction, IV fluids may be a necessary autonomic neuropathy treatment. They help manage symptoms like low blood pressure and dehydration. This may involve hospitalization for hydration therapy. […] GET involves gradually increasing physical activity levels under guidance. A healthcare provider or physical therapist should do it. This can help improve cardiovascular health and manage symptoms like: fatigue; dizziness; shortness of breath.

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