Sacroiliitis to zapalenie stawu krzyżowo-biodrowego.
Diagnostyka i diagnoza

Sacroiliitis, czyli zapalenie stawu krzyżowo-biodrowego, jest istotną przyczyną bólu dolnej części pleców i pośladków, występującą u 10-25% pacjentów z przewlekłym bólem lędźwiowym. Diagnostyka opiera się na szczegółowym wywiadzie, badaniu fizykalnym z testami prowokacyjnymi (Gaenslena, pchnięcie udowe, dystrakcja, kompresja, pchnięcie krzyżowe), gdzie co najmniej 3 z 5 pozytywnych testów sugerują dysfunkcję stawu. Badania obrazowe, zwłaszcza MRI, są kluczowe we wczesnym wykrywaniu sacroiliitis, wykazując obrzęk szpiku kostnego (czułość 65,1%), kapsulitis, enthesitis i synovitis, a także zmiany strukturalne jak nadżerki i sklerotyzacja. RTG i CT mają ograniczoną czułość, a badania nuklearne są obecnie rzadziej stosowane. Diagnostyczna blokada stawu krzyżowo-biodrowego, z redukcją bólu powyżej 50% po iniekcji, stanowi złoty standard potwierdzenia rozpoznania, przewyższając czułość MRI (~54%).

Diagnostyka sacroiliitis (zapalenia stawu krzyżowo-biodrowego)

Sacroiliitis to zapalenie stawu krzyżowo-biodrowego, czyli połączenia między kością krzyżową a kością biodrową. Jest to istotna przyczyna bólu pośladkowego i dolnej części pleców, a jego prawidłowa diagnostyka bywa wyzwaniem ze względu na podobieństwo objawów do innych przyczyn bólu kręgosłupa. Częstość występowania sacroiliitis szacuje się na około 10-25% u pacjentów z przewlekłym bólem dolnej części pleców12. Wczesna diagnostyka i właściwe rozpoznanie są kluczowe dla skutecznego leczenia tego schorzenia.

Badanie fizykalne w diagnostyce sacroiliitis

Pierwszym krokiem w diagnostyce sacroiliitis jest szczegółowy wywiad medyczny i badanie fizykalne. Lekarz zbiera informacje dotyczące charakteru bólu, jego lokalizacji, czynników nasilających lub łagodzących objawy oraz historii ewentualnych urazów lub chorób1. Podczas badania fizykalnego lekarz ocenia:

  • Wzorzec chodu i ewentualne różnice w długości kończyn dolnych1
  • Zakres ruchomości, siłę mięśniową i odruchy w dolnej części pleców oraz kończynach dolnych1
  • Obecność punktów bólowych w okolicy stawów krzyżowo-biodrowych – test Fortina (wskazanie jednym palcem okolicy bólu, typowo przy lub poniżej tylnego górnego kolca biodrowego)2

Szczególnie istotne są testy prowokacyjne stawu krzyżowo-biodrowego, które polegają na wywołaniu bólu poprzez zwiększenie nacisku na staw i okoliczne mięśnie3. Do najczęściej stosowanych testów prowokacyjnych należą:

  • Test Gaenslena – pacjent leży na plecach, jedna noga jest wyprostowana i opuszczona poza krawędź stołu, podczas gdy druga jest zgięta w kierunku klatki piersiowej4
  • Test pchnięcia udowego (thigh thrust) – ucisk na zgięte kolano przy zablokowanym miednicy4
  • Test dystrakcji – wywieranie pionowo skierowanej siły na przednie kolce biodrowe5
  • Test kompresji – wywieranie nacisku na miednicę w pozycji bocznej6
  • Test FABER (Flexion, Abduction, External Rotation) – zginanie, odwodzenie i rotacja zewnętrzna nogi5
  • Test pchnięcia krzyżowego – nagły nacisk na kość krzyżową przy pacjencie leżącym na brzuchu5

Istotnym kryterium diagnostycznym jest reguła mówiąca, że co najmniej 3 z 5 pozytywnych testów prowokacyjnych (Gaenslen, pchnięcie udowe, dystrakcja, kompresja i pchnięcie krzyżowe) wskazują na dysfunkcję stawu krzyżowo-biodrowego27. Warto zaznaczyć, że pojedyncze testy mają niską czułość i swoistość, dlatego ich kombinacja jest kluczowa dla właściwej diagnostyki4.

Badania obrazowe w diagnostyce sacroiliitis

Badania obrazowe odgrywają istotną rolę w diagnozowaniu sacroiliitis, choć każda z metod ma swoje ograniczenia pod względem czułości i swoistości8. Najczęściej stosowane metody obrazowania to:

  • Konwencjonalna radiografia (RTG) – jest zwykle pierwszym badaniem obrazowym, pomimo niskiej czułości i swoistości we wczesnym stadium choroby9. Charakterystyczne zmiany widoczne na zdjęciach RTG obejmują poszerzenie szpary stawowej, zmiany erozyjne i sklerotyczne na brzegach kostnych10. W przypadku wcześniejszego stadium sacroiliitis badanie RTG może być jednak prawidłowe11.
  • Rezonans magnetyczny (MRI) – zrewolucjonizował diagnostykę wczesnej spondyloartropatii osiowej i uznawany jest za najbardziej czułą metodę obrazowania do wykrywania sacroiliitis1213. MRI może wykryć zmiany zapalne we wczesnym stadium choroby, gdy inne badania obrazowe są jeszcze prawidłowe. Najważniejszymi cechami aktywnego sacroiliitis w badaniu MRI są:
    • Obrzęk szpiku kostnego (BMO) – najbardziej czuła cecha (czułość 65,1%)14
    • Zapalenie torebki stawowej (kapsulitis)15
    • Zapalenie przyczepów ścięgnistych (enthesitis)15
    • Zapalenie błony maziowej (synovitis)15

    Ponadto MRI pozwala na wykrycie zmian strukturalnych, takich jak:

    • Nadżerki okołostawowe15
    • Metaplazja tłuszczowa15
    • Sklerotyzacja kości15
    • Mostkowanie kostne/ankyloza15
  • Tomografia komputerowa (CT) – oferuje większą czułość, dokładność i szczegółowe informacje w porównaniu do konwencjonalnej radiografii. Jednak ze względu na wyższe narażenie na promieniowanie, nie zaleca się jej rutynowo do diagnozy lub kontroli9.
  • Badania medycyny nuklearnejscyntygrafia kości, zwłaszcza SPECT (tomografia emisyjna pojedynczych fotonów) z obliczaniem wskaźników lub SPECT w połączeniu z niskodawkową tomografią komputerową (CT) może być czułym i swoistym narzędziem dla diagnozy sacroiliitis16. Jednak ogólnie MRI zastąpił badania medycyny nuklearnej w tej dziedzinie13.

Warto podkreślić, że badania obrazowe mają swoje ograniczenia. MRI może nie wykryć do jednej trzeciej pacjentów z osiową spondyloartropatią, a ujemny wynik badania obrazowego nie powinien zastępować klinicznego podejścia do diagnozy1112.

Badania laboratoryjne w diagnostyce sacroiliitis

W przypadku podejrzenia sacroiliitis o podłożu zapalnym, zaleca się wykonanie badań laboratoryjnych, które mogą obejmować1710:

Obecność podwyższonych markerów zapalnych, takich jak OB i CRP, może wskazywać na aktywny proces zapalny, choć nie jest to specyficzne dla sacroiliitis3. Badania te są bardziej pomocne w określeniu podłoża zapalenia i wykluczeniu innych chorób, niż w potwierdzeniu samego rozpoznania sacroiliitis.

Wykrycie antygenu HLA-B27 może sugerować spondyloartropatię zapalną, szczególnie zesztywniające zapalenie stawów kręgosłupa (ZZSK), jako przyczynę sacroiliitis18. Jednak warto pamiętać, że sam gen HLA-B27 nie oznacza, że rozwinie się spondyloartropatia19.

Diagnostyczne blokady stawu krzyżowo-biodrowego

Najbardziej informatywnym testem dla rozpoznania sacroiliitis jest iniekcja do stawu krzyżowo-biodrowego środków znieczulających i steroidów17. Ta procedura, zwana również blokiem stawu krzyżowo-biodrowego, jest główną formą potwierdzającego testu diagnostycznego, który może pomóc zidentyfikować ból pochodzący ze stawu krzyżowo-biodrowego3.

Jeśli iniekcja powoduje znaczącą redukcję bólu stawu krzyżowo-biodrowego (ponad 50% ulgi w bólu) przez godzinę lub dwie po zastrzyku, jest to uważane za pozytywny lub potwierdzający wynik diagnostyczny20. Oznacza to, że staw krzyżowo-biodrowy jest najprawdopodobniej przyczyną bólu. Jeśli poziom bólu nie zmienia się po iniekcji, staw krzyżowo-biodrowy jest mniej prawdopodobną pierwotną przyczyną20.

Obecnie ten rodzaj blokady diagnostycznej, przeprowadzanej pod kontrolą fluoroskopii lub tomografii komputerowej, jest uznawany za złoty standard w rozpoznawaniu dysfunkcji stawu krzyżowo-biodrowego21. Czułość diagnostyczna MRI dla sacroiliitis wynosi około 54%, podczas gdy blokada diagnostyczna zapewnia bardziej jednoznaczne potwierdzenie21.

Kryteria diagnostyczne spondyloartropatii osiowej

Sacroiliitis jest często pierwszym objawem spondyloartropatii osiowej, w tym zesztywniającego zapalenia stawów kręgosłupa (ZZSK)22. Międzynarodowe Towarzystwo Oceny Spondyloartropatii (ASAS) opracowało kryteria klasyfikacyjne dla spondyloartropatii osiowej, które uwzględniają wykrycie sacroiliitis23.

Według kryteriów ASAS, pacjent z bólem pleców trwającym co najmniej 3 miesiące i w wieku poniżej 45 lat może być klasyfikowany jako cierpiący na spondyloartropatię osiową, jeśli spełnia jeden z dwóch zestawów kryteriów23:

  1. Sacroiliitis potwierdzone w badaniach obrazowych plus co najmniej jedna cecha spondyloartropatii, lub
  2. Obecność antygenu HLA-B27 plus co najmniej dwie cechy spondyloartropatii

Sacroiliitis na obrazowaniu jest definiowane jako aktywny stan zapalny w MRI wysoce sugerujący sacroiliitis związane ze spondyloartropatią lub jednoznaczne sacroiliitis w oparciu o zmodyfikowane kryteria nowojorskie z 1984 roku23.

Warto zauważyć, że klasyfikacja ASAS z 2009 roku pozwala na klasyfikację pacjentów z osiową spondyloartropatią bez jakichkolwiek dowodów obrazowych sacroiliitis, jeśli mają oni wystarczająco dużo pośrednich dowodów choroby24.

Wyzwania diagnostyczne i diagnostyka różnicowa

Diagnostyka sacroiliitis jest wyzwaniem z kilku powodów25:

  • Objawy sacroiliitis są podobne do wielu innych przyczyn bólu dolnej części pleców, w tym rwy kulszowej, przepukliny dysku czy napięcia mięśni25
  • Gruba tkanka mięśniowa otaczająca stawy krzyżowo-biodrowe utrudnia badanie25
  • Różne modalności obrazowania mają ograniczenia w czułości i swoistości11
  • Nie istnieje pojedynczy test, który miałby 100% dokładności diagnostycznej26

W diagnostyce różnicowej sacroiliitis należy uwzględnić227:

  • Spondyloartropatie zapalne (zesztywniające zapalenie stawów kręgosłupa, łuszczycowe zapalenie stawów, reaktywne zapalenie stawów)
  • Infekcyjne zapalenie stawu krzyżowo-biodrowego (np. bruceloza, gruźlica)
  • Choroby zwyrodnieniowe stawów
  • Urazy mechaniczne
  • Zmiany poporodowe
  • Zaburzenia onkologiczne
  • Dysfunkcje stawu krzyżowo-biodrowego o podłożu biomechanicznym

Szczególnie ważne jest różnicowanie sacroiliitis zapalnego od infekcyjnego, które może wymagać natychmiastowej interwencji. Infekcyjne zapalenie stawu krzyżowo-biodrowego jest rzadkie, ale może prowadzić do szybkiego zniszczenia stawu, tworzenia ropni lub zapalenia kości i szpiku, jeśli nie zostanie odpowiednio leczone2829.

Nowoczesne podejścia w diagnostyce sacroiliitis

W ostatnich latach pojawiły się nowe metody wspierające diagnostykę sacroiliitis, w tym3031:

  • Analiza tekstury wspierana uczeniem maszynowym – badania wykazały, że modele analizy tekstury w obrazach T1WI i fsT2WI są wysoce skuteczne w diagnostyce wczesnego zapalenia stawów krzyżowo-biodrowych, przewyższając jakościową ocenę radiologów32
  • Automatyczne algorytmy wykrywania i oceny sacroiliitis w badaniach CT jako przypadkowe znaleziska31
  • Systemy punktacji zapalenia stawów krzyżowo-biodrowych, takie jak SPARCC-SIS (Canadian Spondyloarthritis Research Consortium-Sacroiliac Inflammatory Scoring System), które pomagają ocenić i sklasyfikować zapalenie stawów krzyżowo-biodrowych33

Systemy punktacji, takie jak SPARCC, korelują z klinicznym rozpoznaniem sacroiliitis i mogą kierować klinicystów w leczeniu i podejściu do pacjenta. W systemie SPARCC łagodne zapalenie jest wskazywane przez wynik poniżej 24, umiarkowane – 24-48, a ciężkie – powyżej 4933.

Podejście do diagnostyki sacroiliitis

Skuteczna diagnostyka sacroiliitis wymaga kompleksowego podejścia, które łączy3435:

  • Szczegółowy wywiad medyczny i badanie fizykalne z testami prowokacyjnymi
  • Badania obrazowe, z preferencją dla MRI we wczesnym stadium
  • Badania laboratoryjne, szczególnie w przypadku podejrzenia przyczyny zapalnej
  • Diagnostyczne blokady stawu krzyżowo-biodrowego jako złoty standard potwierdzenia diagnozy

Wczesna i dokładna diagnoza jest kluczowa dla skutecznego zarządzania i leczenia sacroiliitis, pomagając pacjentom wrócić do bardziej aktywnego i wolnego od bólu życia35. Warto pamiętać, że u wielu pacjentów z osiową spondyloartropatią, szczególnie we wczesnych stadiach choroby, sacroiliitis może przejawiać się nietypowym, ostrym, przerywanym lub jednostronnym bólem pochodzącym ze stawu krzyżowo-biodrowego, który może być błędnie interpretowany jako wynikający z przyczyny mechanicznej36.

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  1. 10.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 All About Sacroiliitis
    https://www.spine-health.com/conditions/sacroiliac-joint-dysfunction/all-about-sacroiliitis
    Sacroiliitis typically causes pain in the lower back, buttocks, and legs and may occur due to injury, infection, or autoimmune disorders. […] Research suggests that 10% to 25% of lower back pain may be caused by SI joint inflammation. […] Sacroiliitis may cause SI joint pain affecting the lower back, buttocks, thighs, and legs. […] The condition is often characterized by some combination of the following symptoms and signs: Localized pain. Buttock pain on the affected side is the most common symptom of sacroiliitis. […] Stiffness may occur in the lower back and hip, especially in the morning or after long periods of inactivity. […] It is important to note that groin and lower abdominal pain may also indicate serious medical conditions, such as cauda equina syndrome or infection, so if these symptoms occur, immediate medical attention is warranted.
  • #1 Symptoms and Diagnosis of Sacroiliitis
    https://www.spine-health.com/conditions/sacroiliac-joint-dysfunction/symptoms-and-diagnosis-sacroiliitis
    Sacroiliitis is diagnosed based on a comprehensive review of the patient’s symptoms, signs, and diagnostic tests. […] Diagnosis of sacroiliitis may involve physical exams, clinical tests and image studies. […] There’s no single test that can definitively diagnose sacroiliitis. […] The diagnosis typically involves a combination of physical exams, imaging tests, and blood tests. […] Common steps involved in the diagnostic evaluation of sacroiliitis, include: […] A physical examination at the doctor’s office includes clinical tests that evaluate the range of motion, muscle strength, and reflexes in the lower back and legs. […] The physician analyzes the patient’s gait pattern and any differences in leg length. […] Reviewing the medical history includes asking about the symptoms, such as when the symptoms started and what makes the symptoms worse or better.
  • #2 Sacroilitis: What Is It and How Can You Treat It? | Louisiana Pain Specialists
    https://www.louisianapain.com/sacroilitis-what-is-it-and-how-can-you-treat-it/
    Sacroiliitis, is an inflammatory condition of the sacroiliac joints, and is estimated to effect between 10 and 25 percent of people who suffer from low back pain. This condition is often underdiagnosed because the symptoms it causes are mirrored by numerous other back issues. […] Sacroiliitis is typically the first manifestation of a condition known as axial spondyloarthritis. It is also the first symptom of ankylosing spondylitis. […] Because these symptoms are hallmarks of various mechanical issues of the spine, sacroiliitis is often misdiagnosed, especially in young people. […] The first diagnostic measure for sacroiliitis is a physical exam. During the exam, your doctor will press on (palpate) different areas of the hips and buttocks to find specific points of pain. […] X-rays and MRI may be used in sacroiliitis diagnosis if underlying conditions like ankylosing spondylitis are suspected. […] Diagnostic anesthetic injections are also used to pinpoint the source of a patients lower back pain. If anesthetic injections into the sacroiliac joint provide pain relief, the SI joints are likely the cause of a patients painful symptoms.
  • #2 Sacroiliac Joint Dysfunction: Diagnosis and Treatment | AAFP
    https://www.aafp.org/pubs/afp/issues/2022/0300/p239.html
    The prevalence of sacroiliac (SI) joint dysfunction is approximately 25% in adult patients with chronic low back pain. […] Use the clinical decision rule of at least three out of five positive provocation tests (Gaenslen, thigh thrust, distraction, compression, and sacral thrust) to assist in diagnosing SI joint dysfunction. […] Confirmation of SI joint pain can be made by an image-guided anesthetic block to the SI joint. […] Differentiating SI joint dysfunction from other diagnoses presenting with low back pain requires a complete history and physical examination of the spine, pelvic girdle, and hips as well as a review of other systems to rule out red flags such as history of trauma, unexplained weight loss, fever, bowel and bladder changes, cancer, and night pain. […] Patients with SI joint dysfunction may present with pain that is localized to the area at or just inferomedial to the posterior superior iliac spine as demonstrated in a Fortin finger test or along the gluteal area, lateral hip, lower extremities, and groin.
  • #3 Symptoms and Diagnosis of Sacroiliitis
    https://www.spine-health.com/conditions/sacroiliac-joint-dysfunction/symptoms-and-diagnosis-sacroiliitis
    Imaging studies, such as an x-ray, magnetic resonance imaging (MRI), and computerized tomography (CT) scan, may be ordered to assess the health of the bones, joints, and soft tissue in the lower back and pelvis. […] During a physical examination, physicians conduct several tests that help reproduce the patient’s pain by increasing the pressure of the SI joint and surrounding muscles. […] Clinical tests for Sacroiliitis include: […] An SI joint injection also called an SI joint block is the primary form of confirmatory diagnostic test that can help identify pain originating from the SI joint. […] Blood tests can help identify or rule out inflammatory and/or arthritic conditions that may cause similar symptoms to sacroiliitis, and include checking for inflammation markers, such as C-reactive protein (CRP).
  • #4 Sacroiliac Joint Dysfunction: Diagnosis and Treatment | AAFP
    https://www.aafp.org/pubs/afp/issues/2022/0300/p239.html
    A physical examination should include gait analysis (i.e., reporting of pain with walking, shortened stride length, antalgic gait), range of motion, provocation testing, strength, flexibility, and palpation assessments. […] Motion and provocation tests can assess the SI joint for dysfunction and pain reproduction. […] When individual provocation tests for SI joint dysfunction are used in isolation, they have poor sensitivity and specificity. […] However, if three or more of the tests described reproduce pain, the clinician can reasonably conclude SI joint dysfunction is present. […] Magnetic resonance imaging, computed tomography, and bone scans do not reliably determine the source of pain with SI joint dysfunction, but they may be beneficial in ruling out other diagnoses with symptoms that mimic SI joint dysfunction. […] A contrast-enhanced intra-articular injection with local anesthetic can assist in confirming the SI joint as the source of pain for patients who have not benefited from conservative management or before considering interventional procedures.
  • #5 Sacroiliac Joint Dysfunction Test – PainTEQ | LinQ Procedure for SI joint Dysfunction
    https://www.painteq.com/sacroiliac-joint-dysfunction-test
    Sacroiliitis is a condition of the sacroiliac joint (SI), leading to inflammation or misalignment of the joint. […] There is no single way to give an official diagnosis for SI joint dysfunction. Rather, it is essential to receive a combination of both a physical examination and various diagnostic tests to determine the source of your pain. […] Some sacroiliac joint dysfunction diagnostic tests that your physician may administer include: […] In a sacral thrust test, your physician will place their hands on your sacrum and provide a sudden, quick burst of pressure to one or both sides of your pelvis while you lie face down. […] With a distraction test, you will lie on your back while the physician applies vertically oriented force to both the anterior iliac spines. […] In the FABER test, you lay on your back as your leg is placed in a figure-4 position.
  • #6 Sacroiliac Joint Dysfunction Test – PainTEQ | LinQ Procedure for SI joint Dysfunction
    https://www.painteq.com/sacroiliac-joint-dysfunction-test
    The compression test is when your doctor applies downward pressure to the SI joint as you lay on your side. […] There is also a test called diagnostic injection, sometimes called an SI joint block, where your doctor will inject a steroid into the affected SI joint. […] Diagnostic imaging tests such as X-rays, CT scans, and MRIs are not ideal for imaging the SI joints since they only show the bones of your pelvis, which limits what doctors can see in terms of how well your SI joints are lining up with each other.
  • #7 SI Joint Provocative Tests for Diagnosing SI Joint Dysfunction | PainTEQ | LinQ Procedure for SI joint Dysfunction
    https://www.painteq.com/types-of-si-joint-provocative-tests-for-diagnosing-si-joint-dysfunction
    Sacroiliac (SI) joint dysfunction is a significant cause of lower back pain, yet it often remains underdiagnosed. Understanding the diagnostic process, particularly the SI joint provocative tests, is crucial for patients experiencing this type of pain. These tests are designed to replicate the pain and symptoms associated with SI joint dysfunction, aiding healthcare providers in pinpointing the source of discomfort. […] Healthcare providers use a combination of specific physical exam maneuvers, known as provocative tests, to diagnose SI joint dysfunction. Typically, a diagnosis is considered when at least three out of five tests are positive, with either the thigh thrust or compression test being one of them. […] No single physical exam maneuver is diagnostic on its own. A combination of these tests, along with a detailed history and review of imaging, forms the basis of an accurate diagnosis. In the absence of pathognomonic tests, diagnostic SIJ blocks have evolved as the diagnostic standard.
  • #8 Sacroiliitis – early diagnosis is key
    https://pmc.ncbi.nlm.nih.gov/articles/PMC6136407/
    Sacroiliitis, inflammation of the sacroiliac joint (SIJ), may be associated with many rheumatic and nonrheumatic disorders. The diagnosis of sacroiliitis may be difficult in many patients, and awareness of its typical manifestations along with recognition of its diverse presentations and cognizance of the limitations of todays imaging modalities are critical to good clinical practice. […] The various imaging modalities, however, also have their limitations in both sensitivity and specificity, leading to inconclusive descriptions and reports in some patients. […] This review provides a didactic approach to the early diagnosis of sacroiliitis in patients with suspected AxSpA, discussing differential interpretation of data acquired from patients histories, physical examination, and imaging.
  • #9 Sacroiliitis | Radiology Reference Article | Radiopaedia.org
    https://radiopaedia.org/articles/sacroiliitis?lang=us
    Sacroiliitis (rare plural: sacroiliitides) is an inflammation of one or both sacroiliac (SI) joints. It is a common cause of buttocks or lower back pain and can manifest as a wide range of disease processes. […] Conventional radiography remains the first line of imaging despite its poor sensitivity and specificity in early disease. Specific sacroiliac joint views are helpful in the evaluation and comparing both sides of sacroiliac joints. […] CT examinations offer greater sensitivity, accuracy and detailed information compared to plain radiography. However, due to higher radiation exposure, it is not advisable to use CT for diagnosis or follow-up purposes. […] Though not routinely used for evaluating the sacroiliac joints, MRI is capable of identifying early inflammatory changes of joints when other imaging is negative and excludes other differential causes such as disc prolapse which may resemble clinical symptoms of sacroiliitis.
  • #10 Sacroiliac Joint Injury Workup: Approach Considerations, Laboratory Studies, Imaging Studies
    https://emedicine.medscape.com/article/96054-workup
    Use of imaging studies when evaluating sacroiliac pathology is a source of controversy among clinicians because whether normal and abnormal radiographic studies can help differentiate symptomatic versus nonsymptomatic patients is unclear. […] The usual SIJ examination is performed using anteroposterior pelvis/lumbar spine radiography. […] Joint widening with erosive and sclerotic changes at the bony margins may be suggestive of inflammatory sacroiliitis. […] Magnetic resonance imaging (MRI) is not generally used for evaluating the SIJ, although it can be a valuable tool to help exclude disc herniation (especially at L5-S1) as part of the SIJ dysfunction differential diagnosis. […] In brief, image-guided injections are the gold standard to identify sacroiliac joint dysfunction documenting both the provocation of symptoms when inflated and relief following local anesthetic infiltration.
  • #10 Sacroiliac Joint Injury Workup: Approach Considerations, Laboratory Studies, Imaging Studies
    https://emedicine.medscape.com/article/96054-workup
    In a patient with sacroiliitis, inflammatory origins (eg, ankylosing spondylitis [AS], psoriatic arthritis) must be considered. The following laboratory studies are appropriate when an inflammatory disorder is suspected in a young patient: Complete blood cell (CBC) count, Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) level, Antinuclear antibody (ANA) profile, Human leukocyte antigen (HLA)-B27 status, Rheumatoid factor (RF) value. […] In patients in whom the pain has become chronic, clinicians need to consider whether the patients may have secondary reactive depression. Testing for hypothyroidism, cortisol abnormalities, or other metabolic or endocrine imbalances may be appropriate as part of the workup for a patient with depression. […] Prostate-specific antigen (PSA) testing, serum protein electrophoresis/urine protein electrophoresis, and other laboratory tests used to investigate for malignancy are appropriate for older patients who have not improved with initial care and may have symptoms warranting further investigation.
  • #11 Sacroiliitis – early diagnosis is key
    https://pmc.ncbi.nlm.nih.gov/articles/PMC6136407/
    The diagnosis of sacroiliitis is heavily dependent on confirmatory imaging. […] Thus, to arrive at good medical practice, one needs knowledge of the characteristic clinical manifestations of sacroiliitis together with recognition of its diversity in presentation and awareness of the limitations of the presently available imaging tools. […] Physical examination of a patient with sacroiliitis is never 100% diagnostic, as every manifestation of sacroiliitis can be mimicked by other pelvic or low back diseases. […] Conventional radiography is frequently normal in early sacroiliitis. […] Similarly, bone scintigraphy has low sensitivity, and MRI can miss up to one-third of the patients with AxSpA as well. […] The report of negative imaging should not replace clinical considerations and a reasoned approach to the diagnosis.
  • #12 Sacroiliitis – early diagnosis is key | JIR
    https://www.dovepress.com/sacroiliitis-early-diagnosis-is-key-peer-reviewed-fulltext-article-JIR
    The true negative scintigraphy in patients with back pain due to mechanical causes (specificity) was calculated as 78%, resulting in relatively low likelihood ratio of between 2.5 and 3 when scintigraphy was used for this diagnostic purpose, significantly lower than that of magnetic resonance imaging (MRI), estimated as up to 10.4, depending on the MRI feature assessed. […] MRI of the SIJs and of the spine has revolutionized diagnosis of early SpA. […] With potentially effective treatment to be used in a narrow window of opportunity for disease control, MRI was rapidly embraced as a dominant diagnostic tool and at the same time included into the classification criteria for AxSpA, becoming the cornerstone of SpA diagnosis. […] The presence of characteristic structural lesions on MRI improves diagnostic accuracy and was therefore advocated as a consideration in the ASAS classification criteria update. […] Thus, the report of negative imaging should not replace clinical considerations and a reasoned approach to the diagnosis.
  • #13 Imaging of sacroiliitis: Current status, limitations and pitfalls – Tsoi – Quantitative Imaging in Medicine and Surgery
    https://qims.amegroups.org/article/view/22799/html
    The clinical need to diagnose sacroiliitis at an earlier stage has led to the sacroiliac joints being more frequently imaged, particularly with magnetic resonance imaging (MRI). […] MRI is the most sensitive imaging technique to detect sacroiliitis. […] Even if the radiographs are normal and axial SpA is strongly suspected clinically, MRI examination is still usually performed to detect sacroiliitis. […] MRI has replaced nuclear medicine studies in this regard. […] The most prevalent, reliable and diagnostic MRI feature of active sacroiliitis is bone marrow oedema. […] Bone marrow oedema needs to be significant in degree before a diagnosis of sacroiliitis can be made. […] Not every sacroiliac joint abnormality is an inflammatory sacroiliitis. While it is important not to overlook inflammatory sacroiliitis, it is equally important not to over-diagnose this entity in someone who does not have sacroiliitis.
  • #14 How sensitive and specific are MRI features of sacroiliitis for diagnosis of spondyloarthritis | Journal of the Belgian Society of Radiology
    https://jbsr.be/articles/10.5334/jbr-btr.94
    Objective: To determine the sensitivity and specificity of MRI features of sacroiliitis in spondyloarthritis (SpA). […] MRI showed active inflammation in 42% of patients (bone marrow oedema (BMO) (41.5%), capsulitis (3.3%), enthesitis (2.5%)) and structural changes in 48.8% of patients (erosion (25%), fat infiltration (31.6%), sclerosis (32%) and ankylosis (7.6%)). BMO was the MRI feature with the highest sensitivity (65.1%) for diagnosis of SpA. […] BMO is moderately sensitive and specific for diagnosis of SpA in patients with inflammatory back pain. BMO concomitant with enthesitis, capsulitis, ankylosis or erosion increases the specificity. Concomitant fat infiltration or sclerosis decreases the specificity for diagnosis of SpA. Of all lesions, erosion had by far the highest positive likelihood ratio for diagnosis of SpA.
  • #15 Prevalence of sacroiliitis and acute and structural changes on MRI in patients with psoriatic arthritis | Scientific Reports
    https://www.nature.com/articles/s41598-020-68456-7
    According to some authors, radiological involvement of the sacroiliac joint is one of the earliest signs of PsA, preceding clinical manifestations in approximately 30% of patients. […] Sacroiliitis was significantly associated with peripheral joint erosion (p=0.043), high psoriasis activity and severity scores (PASI) (p=0.041) and early onset of PsA (p<0.001). [...] In our evaluation of the MRI images we employed the definition of sacroiliitis in axial spondyloarthritis given by the ASAS/OMERACT MRI group, according to which active inflammatory lesions in sacroiliac joints are described as bone marrow edema (STIR images) or osteitis (post-gadolinium T1 images). [...] The most prevalent acute structural change observed on MRI was subchondral bone edema (26.7%; n=12), followed by enthesitis (20%; n=9), capsulitis (17.8%; n=8) and synovitis (8.8%; n=4). The most prevalent chronic structural change was periarticular erosion (26.7%; n=12), followed by fat metaplasia (13.3%; n=6), bone sclerosis (11.1%; n=5) and bone bridge/ankylosis (2.2%; n=1).
  • #16 Radionuclide Methods in the Diagnosis of Sacroiliitis in Patients with Spondyloarthritis: An Update (Abstract) | Rambam Maimonides Medical Journal
    https://www.rmmj.org.il/issues/31/articles/638
    Sacroiliitis, inflammation of the sacroiliac joint (SIJ), is the hallmark of ankylosing spondylitis and spondyloarthritis (SpA) in general. […] This review suggests that bone scintigraphy, particularly single-photon emission computed tomography (SPECT) with calculation of indices, or SPECT in combination with low-dose computed tomography (CT) can be a sensitive and specific tool for the diagnosis of sacroiliitis and can be used as part of the individualized approach to the diagnosis of axial SpA. […] In addition, [18F]fluoride positron emission tomography (PET)/CT imaging and immunoscintigraphy, using labeled monoclonal anti-cytokine anti-bodies, are promising methods of current scientific interest in this field.
  • #17 Sacroiliitis – StatPearls – NCBI BookshelfTwitterFacebookLinkedInGitHubNCBI Insights BlogTwitterFacebookYoutube
    https://www.ncbi.nlm.nih.gov/books/NBK448141/
    If an inflammatory condition is suspected, consider ordering complete blood cell count, erythrocyte sedimentation rate, C-reactive protein, antinuclear antibody, human leukocyte antigen (HLA-B27), and rheumatoid factor. […] The most informative test for the diagnosis of sacroiliitis is SI joint injection with local anesthetics and steroids. If this procedure relieves the pain, it is likely that the inflammation at this site was the cause of the pain.
  • #18
    https://www.nhs.uk/conditions/ankylosing-spondylitis/diagnosis/
    Ankylosing spondylitis (AS) can be difficult to diagnose because the condition develops slowly and there’s no definitive test. […] If your GP suspects AS, they may arrange blood tests to check for signs of inflammation in your body. Inflammation in your spine and joints is a main symptom of the condition. […] A diagnosis of AS can usually be confirmed if an X-ray shows inflammation of the sacroiliac joints (sacroiliitis) and you have at least 1 of the following: at least 3 months of lower back pain that gets better with exercise and doesn’t improve with rest, limited movement in your lower back (lumbar spine), limited chest expansion compared with what is expected for your age and sex. […] If the MRI scan shows inflammation of the sacroiliac joints you’ll be diagnosed with non-radiographic axial spondyloarthritis. This is another type of axial spondyloarthritis. […] Sometimes inflammation does not show up on an X-ray or an MRI scan. In this case you might be diagnosed with non-radiographic axial spondyloarthritis if you have the HLA-B27 gene variant and have symptoms of the condition.
  • #19 Axial Spondyloarthritis
    https://rheumatology.org/patients/axial-spondyloarthritis
    Correct diagnosis requires a doctor to assess the patients medical history and do a physical exam. The doctor also may order imaging and blood tests. X-ray changes of the sacroiliac joints, known as sacroiliitis, are a key sign of axial spondyloarthritis. […] The HLA-B27 gene is often present in axial spondyloarthritis, but having this gene does not mean spondyloarthritis will develop.
  • #20 SI Joint Dysfunction Tests | SI-BONE
    https://si-bone.com/si-joint-diagnosis/si-joint-dysfunction-tests
    The most widely used method to accurately determine the cause of SI joint pain is to inject the SI joint with local anesthetic. […] If the injection results in a significant decrease in SI joint pain (more than 50% pain relief) for an hour or two after the injection, then this is considered a positive or confirmatory diagnostic injection. This means your SI joint is most likely the cause of your pain. […] If the level of pain does not change after the injection, the SI joint is less likely to be the primary cause.
  • #21 Etiopathogenesis of sacroiliitis: implications for assessment and management
    https://www.epain.org/journal/view.html?doi=10.3344/kjp.2020.33.4.294
    Sacroiliitis is a painful inflammation of the sacroiliac joint which is particularly challenging to diagnose. […] The presence or absence of chronic sacroiliitis is an important clue in the diagnosis of low back pain. […] Different diagnostic techniques are available for joint inflammation. Imaging techniques, such as simple radiography, can show narrowing of the joint space, fusion, bone erosion, and hardening of the ligaments. […] Sacroiliitis is difficult to detect. Fractures, tumors, and joint structural alterations can be assessed by pelvic X-ray. […] Magnetic resonance imaging (MRI) appears to be useful for evaluating the sacroiliac joints of patients with low back pain. […] The diagnostic sensitivity of MRI for sacroiliitis is about 54%. […] The current gold standard for diagnosis of sacroiliac joint dysfunction is injection of a local anesthetic solution into the joint guided by fluoroscopy or computed tomography: if the injection relieves pain, the sacroiliac joint can be confirmed as the pain source.
  • #22 Sacroilitis: What Is It and How Can You Treat It? | Louisiana Pain Specialists
    https://www.louisianapain.com/blog/sacroilitis-what-is-it-and-how-can-you-treat-it
    Sacroiliitis, is an inflammatory condition of the sacroiliac joints, and is estimated to effect between 10 and 25 percent of people who suffer from low back pain. This condition is often underdiagnosed because the symptoms it causes are mirrored by numerous other back issues. […] Sacroiliitis is typically the first manifestation of a condition known as axial spondyloarthritis. It is also the first symptom of ankylosing spondylitis. […] The first diagnostic measure for sacroiliitis is a physical exam. During the exam, your doctor will press on (palpate) different areas of the hips and buttocks to find specific points of pain. […] X-rays and MRI may be used in sacroiliitis diagnosis if underlying conditions like ankylosing spondylitis are suspected. […] Diagnostic anesthetic injections are also used to pinpoint the source of a patients lower back pain. If anesthetic injections into the sacroiliac joint provide pain relief, the SI joints are likely the cause of a patients painful symptoms.
  • #23 Ankylosing Spondylitis : Symptoms, Diagnosis and Treatment
    https://www.hopkinsarthritis.org/arthritis-info/ankylosing-spondylitis/
    Most patients with AS will experience symptoms of inflammatory back pain due to sacroiliitis and axial arthritis of the spine. […] Because many patients with early AS may not have radiographic evidence of sacroiliitis, the Assessment of Spondyloarthritis International Society (ASAS) has generated classification criteria for axial SpA. […] The ASAS criteria for axial SpA mandates patients have back pain for 3 months and be 45 years of age while fulfilling 1 of the following 2 sets of criteria: […] Set 1: Sacroiliitis on imaging* and 1 SpA feature** […] *Sacroiliitis on imaging is based on active inflammation on MRI highly suggestive of sacroiliitis associated with SpA, or on definite sacroiliitis based on the 1984 Modified New York Criteria.
  • #24 Sacroiliitis – early diagnosis is key
    https://pmc.ncbi.nlm.nih.gov/articles/PMC6136407/
    The example of such an organized approach to the diagnosis of AxSpA, a disease where sacroiliitis is a cornerstone of the diagnosis, was suggested 10 years ago. […] This approach is based on the presence of characteristic clinical and laboratory features of the disease allowing for diagnosis in the absence of any positive imaging of sacroiliitis in patients with enough indirect evidence of the disease. […] Accordingly, the 2009 ASAS classification criteria allow classification of patients with AxSpA without any imaging evidence of sacroiliitis.
  • #25 Sacroiliitis – Orthoanswer
    https://www.orthoanswer.org/hip/sacroiliitis/
    Sacroiliitis can be difficult to diagnose, and it may be mistaken for other causes of low back pain, including sciatica, herniated disks and strained muscles. […] Screening and diagnosis of sacroiliitis is difficult, but your doctor may confirm a diagnosis based on: […] Localized pain that seems to be on or around your sacroiliac joints, which a doctor can determine by pressing on your sacroiliac region while you move in certain ways to gently stress the sacroiliac joint. […] X-rays of your sacroiliac joints […] CT scan or magnetic resonance imaging (MRI) scan of your sacroiliac joints […] Cultures of fluid from the sacroiliac joint […] Blood culture, if the cause appears to be an infection. […] This condition is sometimes hard to diagnose because thick muscle tissue surrounds the sacroiliac joints, so their location deep in the muscles of your buttocks makes these joints hard to examine. […] Additionally, diagnosis is difficult because the signs and symptoms of sacroiliitis are similar to many other causes of low back pain.
  • #26
    https://www.orthobullets.com/spine/422812/sacroiliac-joint-dysfunction
    Sacroiliac Joint Dysfunction is a degenerative condition of the sacroiliac joint resulting in lower back pain. […] Diagnosis is made clinically with pain just inferior to the posterior superior iliac spine that is made worse with hip flexion, abduction, and external rotation. […] 3 positive tests is highly suggestive of the diagnosis. […] no single test has 100% diagnostic accuracy. […] SI joint views: AP, lateral, flexion and extension views of the lumbar spine to identify other spinal pain generators. […] 60% success rate in pain relief at 6 months; 75% reduction in SI joint pain following a single injection is confirmatory of the diagnosis. […] 50% reduction in SI joint pain following two injections. […] SI joint corticosteroid injections can be used as both a diagnostic and therapeutic injection.
  • #27 Brucellosis and sacroiliitis: A differential diagnosis to keep in mind | Revista Colombiana de Reumatología (English Edition)
    https://www.elsevier.es/es-revista-revista-colombiana-reumatologia-english-edition–474-articulo-brucellosis-sacroiliitis-a-differential-diagnosis-S2444440522000061
    Brucellosis and sacroiliitis: A differential diagnosis to keep in mind […] Sacroiliitis is a major criterion for its diagnosis, associated with minor criteria such as arthritis, dactylitis and enthesitis. […] In brucellosis, osteoarticular involvement is the most common complication, whether in the form of peripheral arthritis, sacroiliitis or spondylitis. […] The follow-up of patients with brucellosis is of utmost importance due to the possibility of relapses in up to 10% of the cases in the first year after infection, whose presentation is usually milder than the initial clinical picture. […] Sacroiliitis due to brucellosis is a differential diagnosis to be taken into account.
  • #28 Septic Sacroiliitis: The Overlooked Diagnosis – Page 3
    https://www.medscape.com/viewarticle/410460_3
    Infection of the sacroiliac joint is extremely rare; fewer than 200 confirmed cases (only 16 caused by Salmonella) are reported in the English language literature. […] Thus, the possibility of sacroiliac infection must always be considered with the described clinical scenarios. […] Early diagnosis of a sacroiliac joint infection is facilitated by specific physical findings, including fever, posterior sacroiliac joint tenderness, pain with posterior pelvic compression, straight leg raising sign, Gaenslen’s sign, and positive results on Patrick’s test. […] More recently, however, several reports have shown MRI of the pelvis to be far more sensitive and specific than nuclear medicine studies in rendering a correct diagnosis of sacroiliac infection. […] In conclusion, septic sacroiliitis is a rare illness that manifests with the signs and symptoms of more common problems. For this reason, its diagnosis is frequently overlooked and delayed. When clinical symptoms and signs are suggestive of this infection, routine blood tests and an MRI of the hips and pelvis should be obtained. With a confirmed diagnosis, immediate CT-guided needle biopsy and culture followed by appropriate antibiotic therapy will usually produce an excellent clinical outcome.
  • #29 Sacroiliitis: Managing Your Symptoms to Reduce Pain
    https://www.verywellhealth.com/what-is-sacroiliitis-296629
    Other laboratory tests are also sometimes helpful in assessing the underlying causes of sacroiliitis. […] The Fortin finger test, also known as the one-finger test for sacroiliac pain, is occasionally used to diagnose pain in the lower back. […] Treatment of sacroiliitis will vary based on the underlying cause. […] If you have sacroiliitis from a spondyloarthritis such as ankylosing spondylitis, medications known as TNF-alpha blocker drugs may be beneficial. […] If sacroiliitis is left untreated, it is unlikely to resolve on its own. […] If your sacroiliitis is caused by an infection and is left untreated, you may experience rapid destruction of the sacroiliac joint, abscess formation, or osteomyelitis, an inflammatory bone condition.
  • #30 Differentiation of Early Sacroiliitis Using Machine-Learning- Supported Texture Analysis
    https://www.mdpi.com/2075-4418/15/2/209
    Objectives: We wished to compare the diagnostic performance of texture analysis (TA) against that of a visual qualitative assessment in identifying early sacroiliitis (nr-axSpA). […] MRI at 3T of the lumbar spine and the sacroiliac joint was performed using oblique T1-weighted (W), fluid-sensitive, fat-saturated (Fs) T2WI images. […] The qualitative scores of the two readers could significantly distinguish between the healthy controls and the nr-axSpA group and the nr-axSpA and r-axSpA groups (both p < 0.05). [...] Both TA models could significantly distinguish between the healthy controls and the nr-axSpA group and the nr-axSpA group and the r-axSpA group (both p < 0.05). [...] In terms of distinguishing between the healthy control and nr-axSpA groups, both the TA models were superior to the qualitative scores of the two readers (all p < 0.05).
  • #31 [1908.05663] Automatic detection and diagnosis of sacroiliitis in CT scans as incidental findings
    https://arxiv.org/abs/1908.05663
    Early diagnosis of sacroiliitis may lead to preventive treatment which can significantly improve the patient’s quality of life in the long run. […] We have developed a new automatic algorithm for the diagnosis and grading of sacroiliitis CT scans as incidental findings, for patients who underwent CT scanning as part of their lower back pain workout. […] Automatic computer-based analysis of CT scans has the potential of being a useful method for the diagnosis and grading of sacroiliitis as an incidental finding.
  • #32 Differentiation of Early Sacroiliitis Using Machine-Learning- Supported Texture Analysis
    https://www.mdpi.com/2075-4418/15/2/209
    Based on MR imaging, the T1WI-TA and fsT2WI-TA models were highly effective for the early diagnosis of sacroiliac joint arthritis. […] The T1WI-TA model significantly improved the early diagnostic efficacy for sacroiliac arthritis compared to that of the qualitative scores of the readers, while the efficacy of the fsT2WI-TA model was comparable to that of the readers.
  • #33
    https://link.springer.com/article/10.1007/s10067-024-06979-4
    To reveal the differences by comparing the magnetic resonance imaging (MRI) findings of patients with clinically symptomatic sacroiliitis with those undergoing sacroiliac imaging for other reasons using the Canadian Spondyloarthritis Research Consortium-Sacroiliac Inflammatory Scoring System (SPARCC-SIS). […] The SPARCC-SIS scoring system is used to evaluate and grade the inflammation of the sacroiliac joints. Mild inflammation is indicated by a score below 24, moderate by a score of 24-48, and severe by a score above 49. […] In this study, the SPARCC scoring method, which shows the severity of sacroiliac joint inflammation, correlates with the clinical diagnosis of sacroiliitis. […] In cases with suspected sacroiliitis, except for extraordinary reasons, it can be evaluated with MRI without contrast material and can be graded to guide the clinician in treatment and approach.
  • #34 Diagnosis and treatment of inflammatory sacroiliitis | Centro Médico Teknon
    https://www.teknon.es/en/especialidades/castro-dominguez-francisco/frequent-questions/diagnosis-treatment-inflammatory-sacroiliitis
    Diagnosis and treatment of inflammatory sacroiliitis. […] Sacroiliitis can be difficult to diagnose, as its symptoms may resemble other lower back disorders. Some of the procedures and tests that can help in the diagnosis include: […] Physical examination: The doctor may perform a series of physical maneuvers to evaluate the pain and determine the source. […] Imaging tests: X-rays, magnetic resonance imaging (MRI), and computed tomography (CT) can help visualize the sacroiliac joints and detect signs of inflammation or damage. […] Blood tests: Blood tests can help identify markers of inflammation and may also be useful in ruling out other conditions. […] Sacroiliac joint injection: If injection of an anesthetic into the sacroiliac joint relieves pain, it may be indicative of sacroiliitis. […] Treatment of sacroiliitis usually involves a combination of medication and physical therapy. […] It is important to remember that each case is unique and that the treatment plan must be personalized for each patient.
  • #35 Sacroiliitis | Sacroiliac Joint Pain | Your Complete Guide
    https://benchmarkphysio.com.au/sacroiliitis-symptoms-diagnosis-treatment/
    Diagnosing sacroiliitis involves physical examinations, imaging tests, and possibly blood tests to accurately assess the condition and its underlying causes. […] During the initial consultation, your healthcare provider will conduct a thorough examination of your back, hips, and legs. […] The physical exam may include: Range of Motion Tests: Your provider might have you perform movements to assess the range of motion in your hips and legs. […] Imaging tests are crucial for visualising the bones and tissues of the sacroiliac joints and surrounding areas. […] These diagnostic tools and methods allow healthcare providers to accurately diagnose sacroiliitis and tailor a treatment plan that addresses the specific needs and conditions of the patient. Early and precise diagnosis is key to effectively managing and treating sacroiliitis, helping patients return to a more active and pain-free life.
  • #36 Sacroiliitis – early diagnosis is key | JIR
    https://www.dovepress.com/sacroiliitis-early-diagnosis-is-key-peer-reviewed-fulltext-article-JIR
    It should be remembered that many patients with AxSpA, particularly at early stages of the disease, can present with atypical acute, intermittent or unilateral pain originating from the SIJ, which may be misinterpreted as secondary to a mechanical cause. […] Physical examination of the SIJ includes joint palpation and provocation tests aimed to induce pain while stressing the SIJ. […] These provocation tests can be sensitive enough to detect SIJ pain and can further confirm the diagnosis of SIJ disease but have low specificity and may lead to false-positive conclusions if unsupported by further investigations. […] Traditionally, imaging of the SIJ starts with a roentgenogram (X-ray). However, changes of the SIJ seen on X-ray films are not sensitive or specific enough, at least in the early stages of sacroiliitis.