Ostra zespół niewydolności oddechowej
Charakterystyka, pielęgnacja i opieka

Ostry zespół niewydolności oddechowej (SARS) wywołany przez koronawirusa SARS-CoV charakteryzuje się szybkim początkiem objawów w ciągu 2-10 dni po ekspozycji, z gorączką powyżej 38°C, suchym kaszlem, dusznością oraz bólami mięśniowymi i głowy. W około 25% przypadków rozwija się ARDS wymagający wentylacji mechanicznej, a śmiertelność wynosi 10-15%. Diagnostyka opiera się na obrazie klinicznym, historii ekspozycji i badaniach laboratoryjnych, które wykazują leukopenię i trombocytopenię. Leczenie jest głównie wspomagające, obejmujące tlenoterapię, wentylację mechaniczną z objętością oddechową 6 ml/kg masy ciała, wysokie PEEP (utrzymanie PaO2 > 55 mm Hg) oraz stosowanie leków przeciwgorączkowych i antybiotyków w przypadku nadkażenia bakteryjnego. Eksperymentalne terapie, takie jak rybawiryna, kortykosteroidy, lopinawir/rytonawir oraz osocze ozdrowieńców, nie mają jednoznacznie potwierdzonej skuteczności.

Wprowadzenie do ostrego zespołu niewydolności oddechowej

Ostra zespół niewydolności oddechowej (ang. Severe Acute Respiratory Syndrome, SARS) to poważna choroba zakaźna układu oddechowego, wywołana przez koronawirusa SARS-CoV. Choroba po raz pierwszy pojawiła się w południowych Chinach pod koniec 2002 roku, a następnie szybko rozprzestrzeniła się do 29 krajów na całym świecie, powodując duże ogniska epidemii w Hongkongu, Tajwanie, Singapurze, Wietnamie i Toronto w Kanadzie.12 Między lutym a lipcem 2003 roku zdiagnozowano SARS u ponad 8437 pacjentów w 25 krajach. Wybuch epidemii w Hongkongu był dramatyczny ze względu na bliskość geograficzną prowincji Guangdong w Chinach, gdzie zgłoszono pierwszy przypadek SARS.1

SARS został opisany jako szybko postępujące, czasami śmiertelne zapalenie płuc, z współczynnikiem śmiertelności wynoszącym około 10-15%, które często wymaga intensywnej opieki medycznej.13 Główne powody przyjęcia pacjentów z SARS na oddział intensywnej terapii (OIT) to postępująca duszność i hipoksemia wymagająca wentylacji mechanicznej.1 Około 25% pacjentów ze zdiagnozowanym SARS rozwija zespół ostrej niewydolności oddechowej (ARDS) i wymaga wentylacji mechanicznej.4

Objawy kliniczne i diagnostyka SARS

Objawy SARS zwykle zaczynają się pojawiać w ciągu 2-10 dni po ekspozycji na wirusa. Początkowe objawy przypominają grypę, ale są bardziej nasilone, zwłaszcza u osób starszych.56 Charakterystyczne objawy kliniczne obejmują:

W badaniach laboratoryjnych SARS powoduje zmniejszenie liczby białych krwinek i płytek krwi (komórek odpowiedzialnych za krzepnięcie).9 W ciągu tygodnia od początku choroby, u większości pacjentów rozwija się zapalenie płuc, które można zidentyfikować w badaniach radiologicznych klatki piersiowej.10

Diagnoza SARS jest stawiana na podstawie objawów klinicznych, historii podróży lub kontaktu z osobami chorymi, oraz badań laboratoryjnych. W przypadku podejrzenia SARS, pacjenta należy natychmiast skierować do lekarza i odizolować w szpitalu.11

Mechanizm transmisji wirusa SARS-CoV

SARS rozprzestrzenia się głównie poprzez bliski kontakt osobisty z osobą zakażoną. W kontekście SARS, bliski kontakt oznacza opiekę nad osobą z SARS, zamieszkiwanie z taką osobą lub bezpośredni kontakt z wydzielinami z dróg oddechowych lub płynami ustrojowymi pacjenta z SARS.12

Wirus przenosi się przede wszystkim przez kropelki zakażone wirusem. Kropelki te rozprzestrzeniają się w powietrzu podczas mówienia, kaszlu i kichania.13 Transmisja wirusa może również nastąpić poprzez kontakt z zanieczyszczonymi przedmiotami (fomity) oraz potencjalnie drogą powietrzną.14

Pracownicy służby zdrowia są szczególnie narażeni na zakażenie SARS-CoV, zwłaszcza ci wykonujący procedury generujące aerozol, takie jak intubacja czy nebulizacja.15 Podczas epidemii SARS co piąta osoba zakażona była pracownikiem ochrony zdrowia, który opiekował się pacjentem z SARS; prawie 2000 pracowników ochrony zdrowia zachorowało.16

Okresy zakaźności

Pacjent z SARS jest zakaźny w okresie występowania objawów, takich jak gorączka i kaszel. Z tego powodu pacjenci z SARS muszą być odizolowani od innych osób.17 Chorzy powinni unikać kontaktów z innymi przez co najmniej 10 dni po ustąpieniu gorączki i poprawie objawów oddechowych.18

Opieka pielęgniarska nad pacjentem z SARS

Opieka pielęgniarska nad pacjentami z SARS stanowi wyjątkowe wyzwanie ze względu na zakaźny charakter choroby i potrzebę rygorystycznych środków kontroli zakażeń. Poniżej przedstawiono kluczowe aspekty opieki pielęgniarskiej nad pacjentami z SARS.1920

Izolacja i środki ostrożności

Pacjenci z podejrzeniem lub potwierdzonym SARS powinni być umieszczeni w izolacji, najlepiej w warunkach kontrolowanego podciśnienia:2122

  • Pacjentów należy umieścić w sali z podciśnieniem (AIIR) z zamkniętymi drzwiami
  • Jeśli sala z podciśnieniem jest niedostępna, należy wykorzystać salę jednoosobową z własną łazienką
  • W przypadku braku odpowiednich warunków, można wykorzystać prywatny pokój badań (wyłączyć klimatyzację i otworzyć okno, jeśli niezależne zasilanie powietrzem jest niewykonalne)23

Personel medyczny powinien stosować standardowe środki ostrożności (np. mycie rąk), środki ostrożności dotyczące kontaktu (np. stosowanie fartucha i rękawiczek) oraz środki ostrożności dotyczące przenoszenia drogą powietrzną (np. respirator N-95 i ochrona oczu).24

Opieka nad pacjentem na oddziale intensywnej terapii

Wszyscy pacjenci przyjęci na oddział intensywnej terapii z powodu SARS są zwykle podłączeni do respiratora, posiadają więcej niż dwa cewniki dożylne, linię tętniczą, sondę nosowo-żołądkową (NGT) i cewnik moczowy.25 Opieka nad pacjentami na OIT koncentruje się nie tylko na zapewnieniu wsparcia oddechowego, sercowo-naczyniowego, nerkowego i żołądkowo-jelitowego oraz monitorowaniu, ale co najważniejsze, na wsparciu pacjenta i jego rodziny.26

Około 60% pacjentów przyjętych na OIT wymaga wentylacji mechanicznej do czasu, aż będą mogli być od niej odłączeni.27 Opieka nad pacjentami podłączonymi do respiratora obejmuje:28

  • Rutynową pielęgnację oczu ze sztucznymi łzami, żelem ochronnym lub zaklejaniem powiek
  • Zmianę pozycji ciała i pielęgnację miejsc narażonych na odleżyny
  • Monitorowanie parametrów oddechowych i hemodynamicznych
  • Utrzymanie drożności dróg oddechowych
  • Zapobieganie powikłaniom związanym z unieruchomieniem29

Zasady wentylacji mechanicznej

Postępowanie wentylacyjne u pacjentów z SARS nie różni się znacząco od tego u pacjentów z zespołem ostrej niewydolności oddechowej (ARDS). Kluczowe zalecenia obejmują:30

Należy jednak zauważyć, że stosowanie NIPPV u pacjentów z SARS budzi pewne obawy ze względu na ryzyko rozprzestrzeniania się wirusa przez nieszczelności wokół maski i generowanie aerozolu. Dowody wskazują jednak, że NIPPV jest użyteczną i bezpieczną opcją leczenia pacjentów z SARS z niewydolnością oddechową, pod warunkiem że jest wykonywana przy zachowaniu odpowiednich środków ostrożności i w odpowiednim otoczeniu.32

Monitorowanie i ocena pacjenta

Regularne monitorowanie stanu pacjentów z SARS jest kluczowym elementem opieki pielęgniarskiej. Obejmuje ono:33

  • Regularne pomiary temperatury ciała – co najmniej dwa razy dziennie
  • Monitorowanie częstości oddechów i saturacji krwi tlenem
  • Ocenę dźwięków oddechowych
  • Monitorowanie parametrów życiowych (ciśnienie krwi, tętno, oddech)
  • Ocenę stanu świadomości i ogólnego samopoczucia
  • Monitorowanie równowagi płynowej
  • Regularne badania laboratoryjne, w tym morfologię krwi, poziom elektrolitów i parametry biochemiczne34

Kontrola zakażeń w opiece pielęgniarskiej

Kontrola zakażeń jest kluczowym elementem opieki nad pacjentami z SARS. Personel pielęgniarski powinien stosować następujące środki ostrożności:3536

  • Noszenie maski N95, okularów ochronnych, pełnych osłon twarzy, czepków, wodoodpornych fartuchów z długim rękawem, rękawiczek chirurgicznych i ochraniaczy na buty przed wejściem do sali pacjenta
  • Ograniczenie liczby personelu mającego kontakt z pacjentem
  • Zachowanie minimalnej odległości 2 metrów od pacjenta, gdy tylko jest to możliwe
  • Unikanie ekspozycji na kropelki w przypadku bliskiego kontaktu z pacjentem37

Higiena rąk jest najważniejszą częścią profilaktyki SARS. Należy myć ręce lub czyścić je za pomocą środka do dezynfekcji rąk na bazie alkoholu, zwłaszcza po kontakcie z płynami ustrojowymi.3839

Środki dezynfekujące, takie jak świeży roztwór wybielacza (1/100) lub środki czyszczące zalecane przez szpital, powinny być szeroko dostępne. Stetoskopy, nożyczki i inny sprzęt mają potencjał do rozprzestrzeniania zakażeń i muszą być odpowiednio dezynfekowane.40

Postępowanie z wydzielinami i odpadami medycznymi

Odpowiednie postępowanie z wydzielinami i odpadami medycznymi jest istotne w zapobieganiu rozprzestrzeniania się SARS:41

  • Bielizna powinna być zwijana, a nie wstrząsana. Używaną bieliznę należy umieścić w worku na odpady biologiczne przed wysłaniem do pralni
  • Odpady medyczne nie zostały wskazane jako czynnik w przenoszeniu SARS-CoV, ale należy postępować zgodnie ze standardowymi procedurami ich usuwania
  • Tekstylia nie zostały wskazane jako czynnik w przenoszeniu SARS-CoV
  • Naczynia i sztućce nie zostały wskazane w przenoszeniu SARS-CoV
  • Należy przestrzegać standardowych praktyk w zakresie obsługi i regeneracji używanego sprzętu do opieki nad pacjentem, w tym urządzeń medycznych42

Leczenie farmakologiczne SARS

Nie istnieje specyficzne leczenie SARS, które byłoby udowodnione jako w pełni skuteczne. Leczenie ma charakter głównie wspomagający i obejmuje:4344

  • Antybiotyki do leczenia bakterii powodujących zapalenie płuc (do czasu wykluczenia bakteryjnego zapalenia płuc lub jeśli występuje bakteryjne zapalenie płuc dodatkowo do SARS)
  • Tlen, wspomaganie oddychania (wentylacja mechaniczna) lub terapię oddechową
  • Leki przeciwgorączkowe i przeciwbólowe do łagodzenia objawów
  • Dożylne podawanie płynów4546

Eksperymentalne metody leczenia

Podczas epidemii SARS stosowano różne eksperymentalne metody leczenia, których skuteczność nie została jednoznacznie potwierdzona:47

  • Rybawiryna i kortykosteroidy – były powszechnie stosowane podczas epidemii SARS, choć rybawiryna była krytykowana za brak skuteczności. Kortykosteroidy są skuteczne w obniżaniu gorączki i odwracaniu zmian w zdjęciu rentgenowskim klatki piersiowej, ale mają wadę w postaci sprzyjania replikacji wirusa.48
  • Kombinacja lopinawir/rytonawir – wykazano, że zmniejsza częstość intubacji i występowanie niekorzystnych wyników klinicznych, gdy stosuje się ją z rybawiryną.49
  • Osocze ozdrowieńców – w przypadkach, gdy pacjenci pogarszali się klinicznie pomimo leczenia rybawiryną i kortykosteroidami, leczenie ratunkowe osoczem ozdrowieńców i immunoglobuliną mogło być korzystne.5051
  • Dożylna immunoglobulina (IVIG) – stosowana jako forma terapii ratunkowej dla pacjentów, których stan kliniczny gwałtownie się pogarszał.52
  • Tradycyjna medycyna chińska (TCM) – była szeroko stosowana w Chinach podczas epidemii SARS. Doświadczenia z tradycyjną medycyną chińską są zachęcające, a jej stosowanie jako terapii uzupełniającej powinno być dalej badane.5354

Należy podkreślić, że nie ma silnych dowodów na skuteczność tych metod leczenia.55 Optymalne schematy leczenia SARS pozostają nieuchwytne. Randomizowane kontrolowane badania kliniczne powinny być przeprowadzone, szczególnie poprzez współpracę międzynarodową, aby odkryć najlepszą formę terapii.56

Powikłania SARS i postępowanie

SARS może prowadzić do poważnych powikłań, które wymagają specjalistycznej opieki:57

  • Niewydolność oddechowa – najczęstsze i najpoważniejsze powikłanie, występujące gdy organizm nie jest w stanie uzyskać wystarczającej ilości tlenu lub usunąć wystarczającej ilości dwutlenku węgla
  • Bakteryjne zapalenie płuc – wtórne zakażenie bakteryjne, które może skomplikować przebieg SARS
  • Martwica awaskularna kości – szczególnie niepokojące powikłanie związane ze stosowaniem kortykosteroidów w SARS58
  • Powikłania związane z lekami – hiperglikemia, hipokaliemia, nadciśnienie, krwotok żołądkowo-jelitowy i zakażenia szpitalne związane ze stosowaniem kortykosteroidów, zwłaszcza w wysokich dawkach i przez dłuższy czas59

Wsparcie psychologiczne i edukacja pacjenta

Wsparcie psychologiczne i edukacja pacjenta są istotnymi elementami opieki pielęgniarskiej nad pacjentami z SARS:60

Wsparcie psychologiczne pacjenta i rodziny

Pacjenci z SARS doświadczają znacznego stresu psychologicznego związanego z poważną chorobą, izolacją i strachem przed zarażeniem innych. Wsparcie psychologiczne powinno obejmować:61

  • Regularne kontakty z personelem medycznym, aby zmniejszyć poczucie izolacji
  • Zapewnienie środków komunikacji z rodziną (telefon, wideorozmowy)
  • Informowanie o postępach w leczeniu i wyjaśnianie procedur medycznych
  • Wsparcie emocjonalne i pocieszenie w trudnych momentach
  • W miarę możliwości, ograniczone wizyty osób bliskich z zachowaniem odpowiednich środków ostrożności62

Edukacja pacjenta i rodziny

Edukacja pacjenta i jego rodziny jest kluczowa dla zapobiegania rozprzestrzenianiu się SARS i zapewnienia właściwej opieki po wypisie ze szpitala:63

  • Nauka prawidłowej higieny rąk i technik kaszlu
  • Instrukcje dotyczące noszenia masek i innych środków ochrony osobistej
  • Informacje o transmisji i leczeniu SARS
  • Zalecenia dotyczące izolacji domowej przez co najmniej 10 dni po ustąpieniu gorączki i poprawie objawów oddechowych
  • Instrukcje dotyczące monitorowania objawów i kontaktu z lekarzem w przypadku pogorszenia stanu zdrowia6465

Pacjenci powinni być poinformowani o konieczności ścisłego przestrzegania zaleceń dotyczących wizyt kontrolnych i kontaktu z lekarzem w przypadku problemów zdrowotnych.66

Profilaktyka i kontrola zakażeń w placówkach opieki zdrowotnej

Właściwa kontrola zakażeń w placówkach opieki zdrowotnej jest podstawową metodą zapobiegania rozprzestrzenianiu się SARS:67

Procedury wczesnego wykrywania i izolacji

Wczesne wykrycie i izolacja pacjentów potencjalnie zakażonych SARS-CoV są najważniejszymi interwencjami zapobiegającymi wprowadzeniu SARS-CoV do placówki opieki zdrowotnej:68

  • Wdrożenie skutecznych procedur screeningowych w punktach przyjęć szpitalnych
  • Szybkie odizolowanie pacjentów z podejrzeniem SARS od innych pacjentów
  • Wdrożenie odpowiednich środków izolacji
  • Ograniczenie ruchu pacjentów i transportu poza salą izolacji do celów medycznie niezbędnych69

Ochrona personelu medycznego

Personel medyczny jest szczególnie narażony na zakażenie SARS-CoV. Ochrona personelu obejmuje:7071

  • Stosowanie standardowych środków ostrożności, w tym dobrych praktyk pracy i higieny
  • Używanie środków ochrony osobistej (PPE) odpowiednich dla ekspozycji przenoszonej drogą krwi i drogą powietrzną
  • Odpowiednie szkolenie personelu w zakresie środków kontroli zakażeń
  • Regularny monitoring stosowania PPE
  • Wyłączenie z pracy pracownika, który doświadcza gorączki i objawów ze strony układu oddechowego po kontakcie z pacjentem zakażonym SARS72

Procedury dotyczące specjalnych sytuacji klinicznych

Szczególne środki ostrożności są wymagane w przypadku procedur generujących aerozole, które mogą stanowić zwiększone ryzyko transmisji SARS-CoV:73

  • Podczas wykonywania lub asystowania przy tych procedurach personel powinien nosić pełne wyposażenie ochronne
  • Procedury powinny być wykonywane w sali z podciśnieniem lub izolowanym obszarze
  • Liczba personelu obecnego podczas procedury powinna być ograniczona do minimum
  • Zamiast nawilżania podgrzewanego, które jest powszechnie stosowane u pacjentów podłączonych do respiratora, podczas epidemii zakaźnego wirusa należy używać wymiennika ciepła i wilgoci z filtrem (HMEF) do celów nawilżania74

Zarządzanie zasobami podczas epidemii SARS

Epidemia SARS stanowi wyzwanie dla zdolności placówki opieki zdrowotnej do zaspokojenia potrzeb kadrowych, organizacyjnych i zasobowych:75

  • Podczas epidemii istniejące niedobory kadrowe mogą być spotęgowane przez choroby wśród personelu, strach i obawy związane z SARS oraz izolację i kwarantannę narażonego personelu lub chorych/narażonych członków rodziny
  • Opieka nad pacjentem z SARS wymaga zarówno materiałów jednorazowych (np. PPE), jak i trwałych (np. respiratorów)
  • Doświadczenia z innych krajów wskazują, że epidemia SARS może nie tylko obciążyć zapasy tych zasobów w placówce, ale także wpłynąć na zdolność do zamawiania zapasów uzupełniających76

Epidemia SARS generuje potrzebę szybkiej analizy stanu pacjentów i transmisji w placówce opieki zdrowotnej oraz przekazywania tych informacji urzędnikom zdrowia publicznego, opinii publicznej, prasie i przywódcom politycznym.77

Opieka domowa nad pacjentem z SARS

W przypadku pacjentów z łagodną lub umiarkowaną postacią SARS, opieka domowa może być odpowiednią opcją, pod warunkiem że sytuacja domowa, w tym jej przydatność pod względem kontroli zakażeń, zostanie uznana za odpowiednią.78

Zalecenia dla opieki domowej

W przypadku opieki nad pacjentem z SARS w domu należy przestrzegać ścisłych środków kontroli zakażeń:79

  • Wszystkie osoby w gospodarstwie domowym powinny dokładnie myć ręce często mydłem lub środkami do dezynfekcji rąk na bazie alkoholu, zawsze po kontakcie z płynami ustrojowymi
  • Pacjenci z SARS powinni zakrywać usta i nos podczas kaszlu lub kichania, lub jeśli to możliwe, nosić maskę chirurgiczną podczas bliskiego kontaktu z innymi
  • Członkowie gospodarstwa domowego i inne osoby mające bliski kontakt z pacjentami z SARS powinni być obserwowani pod kątem objawów
  • Członkowie gospodarstwa domowego i inne osoby mające bliski kontakt z pacjentami z SARS powinni mierzyć temperaturę dwa razy dziennie
  • W przypadku wystąpienia gorączki lub objawów ze strony układu oddechowego (kaszel, duszność lub trudności w oddychaniu) należy szukać pomocy medycznej80

Monitorowanie kontaktów

Osoby, które miały kontakt z pacjentem z SARS, powinny być ściśle monitorowane:81

  • Zalecenie dobrowolnej izolacji w domu i codziennego pomiaru temperatury przez 10 dni po kontakcie
  • Zapewnienie codziennych wizyt lub rozmów telefonicznych przez członka służby zdrowia publicznego w celu określenia, czy rozwija się gorączka lub inne objawy zakażenia SARS-CoV
  • Kliniczne dowody SARS u osoby kontaktowej wymagają natychmiastowej oceny klinicznej i izolacji
  • Poinformowanie wszystkich kontaktów o okresie inkubacji i typowych objawach zakażenia SARS-CoV
  • Zachęcanie do wczesnego poszukiwania pomocy medycznej w przypadku wystąpienia objawów82

Bliski kontakt oznacza opiekę nad osobą z SARS, zamieszkiwanie z taką osobą lub bezpośredni kontakt z wydzielinami z dróg oddechowych lub płynami ustrojowymi pacjenta z SARS.83

Edukacja i przygotowanie personelu medycznego

Przygotowanie personelu medycznego do opieki nad pacjentami z SARS jest kluczowym elementem skutecznej kontroli zakażeń:84

Szkolenia i edukacja

Obserwacje pracowników opieki zdrowotnej opiekujących się pacjentami z SARS podczas epidemii w 2003 roku wykazały liczne naruszenia kontroli zakażeń, szczególnie w zakresie stosowania środków ochrony osobistej (PPE). Można je skorygować poprzez:85

  • Kompleksowe szkolenia
  • Zapewnienie odpowiednio dobranych PPE
  • Monitorowanie stosowania PPE
  • Ponowne podkreślenie znaczenia podstawowych środków kontroli zakażeń, w tym higieny rąk, dla kontroli SARS-CoV i innych patogenów układu oddechowego86

Wszyscy pracownicy potencjalnie narażeni na SARS powinni być przeszkoleni w zakresie zagrożeń związanych z tą ekspozycją oraz protokołów obowiązujących w ich placówkach w celu izolacji i zgłaszania przypadków oraz zmniejszenia narażenia.87

Przygotowanie placówek opieki zdrowotnej

Każda placówka opieki zdrowotnej powinna opracować strategię i procedury:88

  • Szybkiego oddzielenia potencjalnych pacjentów z SARS od innych pacjentów
  • Wdrożenia odpowiednich środków izolacji
  • Zapewnienia odpowiednich zasobów i sprzętu
  • Opracowania planów na wypadek niedoborów kadrowych
  • Ustanowienia protokołów komunikacji i raportowania89

Gdy SARS-CoV jest obecny w społeczności otaczającej placówkę opieki zdrowotnej, zapobieganie wejściu nierozpoznanych pacjentów z SARS do placówki będzie niezbędne. Odpowiednie środki nadzoru i badań przesiewowych są szczegółowo opisane w sekcji nadzoru tego dokumentu i w uzupełnieniu B. Ograniczenie dostępu do placówki zwiększy skuteczność środków nadzoru i badań przesiewowych.90

Wnioski i zdobyte doświadczenia

Epidemia SARS dostarczyła cennych lekcji dla przyszłych pandemii wirusowych:91

  • Zasady kontroli zakażeń i zarządzania respiratorami wyciągnięte z epidemii SARS mogą służyć podczas przyszłych epidemii wirusowych
  • Wczesne rozpoznanie i izolacja przypadków są kluczowe dla kontroli rozprzestrzeniania się choroby
  • Ścisłe przestrzeganie środków kontroli zakażeń jest niezbędne do ochrony pracowników opieki zdrowotnej
  • Strategie przedstawione w niniejszym artykule okazały się skuteczne w powstrzymywaniu zakażeń pracowników opieki zdrowotnej podczas epidemii SARS92

Instytucje opieki zdrowotnej na całym świecie stoją przed poważnym wyzwaniem, gdyby SARS miał się ponownie pojawić, a ryzyko jest zwiększone przez jego podobieństwa do innych szczepów koronawirusa pochodzenia zwierzęcego i fakt, że utrzymuje się w rezerwuarach zwierzęcych.93

Pandemia SARS została zakończona dzięki podstawowym środkom zdrowia publicznego i kontroli zakażeń. Kluczem do zapobiegania kolejnej epidemii jest szybkie zidentyfikowanie pierwszych zakażonych pacjentów, zanim zdążą szerzej rozprzestrzenić chorobę.94

Kolejne rozdziały

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  1. 14.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Nursing care of patients with severe acute respiratory syndrome in the intensive care unit: case reports in Hong Kong
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7130354/
    Severe acute respiratory syndrome (SARS) was diagnosed in more than 8437 patients in 25 countries between February and July 2003. […] The outbreak in Hong Kong has been dramatic due to its geographical proximity with Guangdong province, China where the first case of SARS was reported. […] SARS has been described as a rapidly progressive, sometimes fatal pneumonia with a case fatality rate of 7.6% requiring intensive care. […] The purpose of this paper is to share our experiences in caring for critically ill patients with SARS in the intensive care unit to nurses globally in order to reduce SARS morbidity and mortality as well as to protect nurses and other healthcare workers from this disease that is so far threatening the community at large. […] The main reasons for ICU admission of these patients were progressing dyspnoea and hypoxaemia requiring mechanical ventilation.
  • #2 About SARS – MN Dept. of Health
    https://www.health.state.mn.us/diseases/sars/basics.html
    Severe acute respiratory syndrome (SARS) is a viral respiratory illness that first emerged in China in November 2002, and later spread through international travel to 29 countries worldwide causing large outbreaks in Hong Kong; Taiwan; Singapore; Hanoi, Vietnam; and Toronto, Canada. […] Most of the U.S. SARS cases were among travelers returning from other parts of the world with SARS. […] SARS is spread primarily by close person-to-person contact. In the context of SARS, close contact means having cared for or lived with someone with SARS or having direct contact with respiratory secretions or body fluids of a patient with SARS. […] For a severe respiratory illness to be SARS, there has to be a history of travel to a SARS affected area or close personal contact with a person with SARS, within ten days before symptoms start, this is called the epidemiological link.
  • #3 Severe acute respiratory syndrome sars | Health and wellbeing | Queensland Government
    https://www.qld.gov.au/health/condition/infections-and-parasites/viral-infections/severe-acute-respiratory-syndrome-sars
    Severe acute respiratory syndrome (SARS) is caused by a virus called SARS-associated coronavirus. […] Some people with SARS develop severe pneumonia and about 20% will require admission to an intensive care unit. Overall, about 10-15% of people diagnosed with SARS have died. Older people and those with chronic disease are at higher risk. […] If a SARS epidemic recurs and you have travelled to a SARS-affected area in the last 10 days and developed fever, cough or shortness of breath, you should seek urgent medical assessment. As SARS is infectious, always phone the health facility and advise of possible SARS contact before attending. […] There is no specific treatment for SARS. Severe cases need hospitalisation for general supportive healthcare. […] Special precautions are needed for people who are suspected of having SARS and their carers. People may be isolated in hospital or in their home. Staff caring for them, along with any visitors, need to wear masks, eye protection, gloves and gowns to prevent the infection being spread. It is very important for the sick person and all people in contact with them to wash their hands frequently.
  • #4 Lessons from Severe Acute Respiratory Syndrome (SARS) | RT
    https://respiratory-therapy.com/disorders-diseases/critical-care/acute-disorders/lesson-from-sars/
    Principles of infection control and ventilator management taken from the SARS epidemic may serve during future viral outbreaks. […] Twenty-five percent of patients who are diagnosed with SARS develop acute respiratory distress syndrome and will need mechanical ventilation. […] The ventilatory management of patients with SARS does not differ much from that for patients with ARDS alone. […] A low tidal volume lung protective strategy should be adopted, with the target tidal volumes at 6 mL per ideal body weight. […] High levels of positive end-expiratory pressure (PEEP) may be used to maintain a PaO2 greater than 55 mm Hg. […] Noninvasive ventilation (NIV) has been used in early acute respiratory failure to aid in ventilation and reduce intubation rates. […] SARS patients should be nursed in private rooms with a negative pressure system in the intensive care unit.
  • #5
    https://www.advocatehealth.com/health-services/lung-respiratory-care/severe-acute-respiratory-syndrome-sars
    Severe acute respiratory syndrome symptoms typically begin to occur within two to 10 days after being exposed to the virus. Fever is the first noticeable symptom of SARS, followed by flu-like symptoms that intensify over time. […] If you experience any of the above symptoms, its important to rest and drink plenty of fluids. Discuss any over-the-counter medications for symptom relief with your primary care doctor or pharmacist before taking them. If symptoms begin to get worse, seek immediate care. […] Rapid SARS diagnosis is crucial for proper treatment, for preventing SARS complications and to stop the spread of the virus. At Advocate Health Care, your pulmonologist has access to state-of-the-art testing to accurately diagnose severe acute respiratory syndrome. […] There still isnt an effective treatment for SARS coronavirus 1 despite a global effort to develop one. Until an effective treatment is created, your doctor will use advanced care to help ease symptoms and prevent the spread of the virus. Severe acute respiratory syndrome treatment options include: […] At Advocate Health Care, you can trust that youll receive the highest level of care for severe acute respiratory syndrome. Our pulmonologists work closely with any health care support services you may need to coordinate ongoing care and speed recovery from SARS coronavirus 1.
  • #6 Coronaviruses and Acute Respiratory Syndromes (MERS and SARS) – Infections – Merck Manual Consumer Version
    https://www.merckmanuals.com/home/infections/respiratory-viruses/coronaviruses-and-acute-respiratory-syndromes-mers-and-sars
    Symptoms of SARS resemble those of other more common respiratory viral infections but are more severe. They include fever, headache, chills, and muscle aches, followed by a dry cough and sometimes difficulty breathing. […] Most people recovered within 1 to 2 weeks. However, some developed severe difficulty breathing, and about 10% died. […] SARS is suspected only if people who may have been exposed to an infected person have a fever plus a cough or difficulty breathing. […] If doctors think a person may have SARS, the person is isolated in a room with a ventilation system that limits the spread of microorganisms in the air. In the first and only outbreak of SARS, such isolation kept the virus from being transmitted and eventually eliminated it. […] People with mild symptoms need no specific treatment. Those with moderate difficulty breathing may need to be given oxygen. Those with severe difficulty breathing may need mechanical ventilation to aid breathing.
  • #7 Severe Acute Respiratory Syndrome (SARS): a guide for nurses – Massachusetts Nurses Association
    https://www.massnurses.org/2003/07/15/severe-acute-respiratory-syndrome-sars-a-guide-for-nurses/
    Severe Acute Respiratory Syndrome (SARS) is a disease caused by a corona virus that presents with symptoms similar to the common cold. The incubation period is two to ten days from the time of exposure. Suspected cases could present with: […] Suspected SARS patients presenting to healthcare facilities and doctors offices who require assessment for SARS should be diverted by triage or staff to a separate area to minimize transmission to others. These patients should immediately be given a surgical mask and should be instructed to wear a surgical mask at all times. […] The medical personnel should apply the surgical mask to the patient, preferably one that filters expired air. All healthcare personnel should wear N-95 respirators that have been properly fit tested in advance. If N-95 respirators are not available, surgical masks should be worn by personnel.
  • #8 Department of Health | Communicable Disease Service | Severe Acute Respiratory Syndrome (SARS)
    https://www.nj.gov/health/cd/topics/sars.shtml
    Health care providers, administrators, and clinical laboratory directors should report confirmed or suspect cases immediately to their Local Health Department by telephone. […] Severe acute respiratory syndrome (SARS) is a viral respiratory illness that was recognized as a global threat in March 2003. […] The disease is spread by close person-to-person contact, such as caring for, living with or having direct contact with an infected person. […] Symptoms of SARS can vary, but may include high fever, chills, headache, body aches, pneumonia, diarrhea, dry cough, low levels of oxygen in the blood. […] No single medicine can effectively treat SARS. […] Different types of treatment regimens have been used for people who are severely ill and hospitalized including antibiotics, antivirals and steroids.
  • #9 SARS Symptoms, Causes, Treatment, Prevention, Transmission
    https://www.medicinenet.com/severe_acute_respiratory_syndrome_sars/article.htm
    SARS causes a decrease in white blood cells and platelet (clotting cell) counts in the blood. […] SARS is an infectious respiratory illness caused by the coronavirus. […] SARS often affected people caring for a sick individual and spread readily through healthcare facilities until infection-control measures were established. […] During the outbreak, one in about every 20 infected people was a healthcare worker who cared for a patient with SARS; nearly 2,000 healthcare workers became ill. […] Most people with SARS would see a primary-care provider or an emergency medicine doctor as the illness rapidly progressed. […] Depending on the stage of illness, they would be admitted to a hospital as oxygen levels decreased. In the hospital, a person with SARS would likely be managed by a hospitalist or critical-care doctor, with consultations with an infectious disease doctor and a lung doctor (pulmonologist).
  • #10 Severe acute respiratory syndrome (SARS) – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/sars/symptoms-causes/syc-20351765
    SARS is a serious illness that can lead to death. If you have any symptoms of a respiratory infection, call a member of your healthcare team right away. […] Many people with SARS get pneumonia. And sometimes, a machine called a ventilator is needed to help with breathing. SARS is fatal in some cases, often because the body cant get enough oxygen or cant remove enough carbon dioxide. This condition is called respiratory failure. […] Researchers are working on various vaccines for SARS. But none has been tested in humans. If infections caused by the SARS virus happen again, follow some safety measures. The following tips are key if you care for someone who may have SARS: […] Follow these steps for at least 10 days after the persons fever has gone away and any breathing symptoms have gotten better. The Centers for Disease Control and Prevention recommends that an infected person stay home from work or school during this time. Call your healthcare team right away if a fever or other symptoms start within 10 days of close contact with someone who has SARS.
  • #11 Severe acute respiratory syndrome (SARS): MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/007192.htm
    Severe acute respiratory syndrome (SARS) is a serious form of pneumonia. Infection with the SARS virus causes acute respiratory distress (severe breathing difficulty), and sometimes death. […] People who are thought to have SARS should be checked right away by a provider. If they are suspected of having SARS, they should be kept isolated in a hospital. […] Treatment may include: Antibiotics to treat bacteria that cause pneumonia (until bacterial pneumonia is ruled out or if there is bacterial pneumonia in addition to SARS) and to treat bacterial infections that could occur in addition to SARS and Oxygen, breathing support (mechanical ventilation), or chest therapy. […] In some serious cases, the liquid part of blood from people who have already recovered from SARS has been given as a treatment.
  • #12 About SARS – MN Dept. of Health
    https://www.health.state.mn.us/diseases/sars/basics.html
    Severe acute respiratory syndrome (SARS) is a viral respiratory illness that first emerged in China in November 2002, and later spread through international travel to 29 countries worldwide causing large outbreaks in Hong Kong; Taiwan; Singapore; Hanoi, Vietnam; and Toronto, Canada. […] Most of the U.S. SARS cases were among travelers returning from other parts of the world with SARS. […] SARS is spread primarily by close person-to-person contact. In the context of SARS, close contact means having cared for or lived with someone with SARS or having direct contact with respiratory secretions or body fluids of a patient with SARS. […] For a severe respiratory illness to be SARS, there has to be a history of travel to a SARS affected area or close personal contact with a person with SARS, within ten days before symptoms start, this is called the epidemiological link.
  • #13 Severe acute respiratory syndrome (SARS) | healthdirect
    https://www.healthdirect.gov.au/severe-acute-respiratory-syndrome-sars
    Severe acute respiratory syndrome (SARS) is a viral illness that can cause severe pneumonia. […] SARS is spread by contaminated droplets. These droplets are spread from your body through the air from talking, coughing, and sneezing. […] During a SARS outbreak, contact your doctor immediately if you have travelled to a high-risk area in the past 10 days and develop a fever, cough, or breathing difficulties. […] There is no cure, vaccine or specific treatment for SARS. Treatment focuses on managing your symptoms. […] If you develop severe pneumonia, you may need to go to the hospital for treatment to help you breathe. […] SARS can lead to severe symptoms such as shortness of breath. This may progress to severe difficulty breathing, respiratory failure and lead to death. […] If you are caring for someone with SARS, wear personal protective equipment (PPE). This includes wearing a gown, mask, gloves and goggles.
  • #14 SARS | Guidance | Recommendations for Preparedness and Response Activities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/c-healthcare/recommended.html
    Appropriate patient placement is a significant component of effective SARS control. Each healthcare facility should develop a strategy and procedures to: 1) quickly separate potential SARS patients from other patients, and 2) implement appropriate isolation precautions. […] Although most SARS-CoV transmission appears to occur through droplet and contact exposures, transmission by fomites and by the airborne route remain possibilities. Therefore, patients who require hospitalization should be admitted to an Airborne Infection Isolation room (AIIR) or specially adapted SARS unit or ward where they can be managed safely. […] Unrecognized patients were a significant source of transmission during the 2003 SARS outbreak. Thus, rapid reporting and evaluation of persons exposed to SARS-CoV will be an important measure in early identification and isolation.
  • #15 Severe acute respiratory syndrome (SARS) – Health New Zealand | Te Whatu Ora
    https://www.tewhatuora.govt.nz/for-health-professionals/clinical-guidance/communicable-disease-control-manual/severe-acute-respiratory-syndrome-sars
    This guidance supports public health professionals with the prevention and management of SARS species disease cases, contacts and outbreaks […] Health care workers are at high risk, especially those undertaking aerosol-generating procedures, such as intubation or nebulisation. […] In hospital, place cases under airborne and contact precautions throughout the period of communicability. Staff should also wear eye protection and footwear that can be decontaminated or disposed of and use disposable equipment for the case wherever possible. […] Outside hospital, cases should be isolated at home or in some other suitable facility throughout the period of communicability. During this time, household members who are not providing care should be relocated if possible. […] Advise the case and their caregivers of the nature of the infection and its mode of transmission.
  • #16 SARS Symptoms, Causes, Treatment, Prevention, Transmission
    https://www.medicinenet.com/severe_acute_respiratory_syndrome_sars/article.htm
    SARS causes a decrease in white blood cells and platelet (clotting cell) counts in the blood. […] SARS is an infectious respiratory illness caused by the coronavirus. […] SARS often affected people caring for a sick individual and spread readily through healthcare facilities until infection-control measures were established. […] During the outbreak, one in about every 20 infected people was a healthcare worker who cared for a patient with SARS; nearly 2,000 healthcare workers became ill. […] Most people with SARS would see a primary-care provider or an emergency medicine doctor as the illness rapidly progressed. […] Depending on the stage of illness, they would be admitted to a hospital as oxygen levels decreased. In the hospital, a person with SARS would likely be managed by a hospitalist or critical-care doctor, with consultations with an infectious disease doctor and a lung doctor (pulmonologist).
  • #17 Content – Health Encyclopedia – University of Rochester Medical Center
    https://www.urmc.rochester.edu/encyclopedia/content?contenttypeid=90&contentid=P07741
    Severe acute respiratory syndrome (SARS) is a viral illness. SARS is caused by a type of coronavirus called SARS-associated coronavirus (SARS-CoV). […] A child with SARS needs to be kept away from others until the illness is treated and cured. […] A child is more at risk for SARS if they are in an area where SARS is active or if they’ve had contact with a person who has SARS. […] A child with SARS is contagious when having symptoms, such as fever or cough. A child with SARS must be kept away from others. […] SARS is treated with supportive therapy and sometimes with antiviral medicines. Your child may be given IV fluids and oxygen or other breathing help.
  • #18 Severe acute respiratory syndrome (SARS) – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/sars/symptoms-causes/syc-20351765
    SARS is a serious illness that can lead to death. If you have any symptoms of a respiratory infection, call a member of your healthcare team right away. […] Many people with SARS get pneumonia. And sometimes, a machine called a ventilator is needed to help with breathing. SARS is fatal in some cases, often because the body cant get enough oxygen or cant remove enough carbon dioxide. This condition is called respiratory failure. […] Researchers are working on various vaccines for SARS. But none has been tested in humans. If infections caused by the SARS virus happen again, follow some safety measures. The following tips are key if you care for someone who may have SARS: […] Follow these steps for at least 10 days after the persons fever has gone away and any breathing symptoms have gotten better. The Centers for Disease Control and Prevention recommends that an infected person stay home from work or school during this time. Call your healthcare team right away if a fever or other symptoms start within 10 days of close contact with someone who has SARS.
  • #19 Nursing care of patients with severe acute respiratory syndrome in the intensive care unit: case reports in Hong Kong
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7130354/
    All patients admitted to ICU were mechanically ventilated, have more than two intravenous catheters, an arterial line, nasogastric tube (NGT) and indwelling catheter. […] Care of patients in ICU were focused not only towards providing respiratory, cardiovascular, renal, gastrointestinal support and monitoring, but most importantly, patient and family support. […] During the outbreak, our infection control protocol had to be re-visited and revised in accordance with the guidelines for infection control measures revised and released by WHO. […] The importance of infection control is vital in controlling the spread of the disease as the virus is highly contagious. […] About 60% of patients admitted to our ICU required mechanical ventilation until they can be weaned off from the ventilator.
  • #20 Nursing Care Plan For Sars | PDF | Pneumonia | Transmission (Medicine)
    https://www.scribd.com/document/359055963/97081671-Nursing-Care-Plan-for-Sars-docx
    The nursing care plan addresses a patient diagnosed with SARS who presents with a fever, cough, and respiratory symptoms, with goals of reducing the patient’s fever and respiratory symptoms through monitoring, isolation procedures, medication administration, and health education to prevent the spread of infection to others. […] Interventions include respiratory isolation, administering antiviral medications, encouraging proper hand hygiene and coughing techniques, and ensuring the patient understands the transmission and treatment of SARS.
  • #21 Severe Acute Respiratory Syndrome (SARS): a guide for nurses – Massachusetts Nurses Association
    https://www.massnurses.org/2003/07/15/severe-acute-respiratory-syndrome-sars-a-guide-for-nurses/
    Patients presenting with probable SARS should be moved and accommodated in: A negative pressure room with the door closed, A single room with their own bathroom, A private exam room (turn off air conditioning and open window if independent air supply is unfeasible). […] Contact your facilitys infection control personnel and initiate SARS policies and procedures as written by your healthcare facility. Unprotected exposures should be reported immediately and proper documentation completed. […] A member of the staff must be identified as the primary care provider, preferably the staff member that initiated contact with the patient upon their arrival to the facility. The designated staff member will use standard precautions (e.g., hand washing), contact precautions (e.g., use of gown and gloves) and airborne precautions (e.g., N-95 respirator and eye protection).
  • #22 SARS | Guidance | Infection Control | Healthcare Facilities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/i-infection/healthcare.html
    Follow recommended precautions for hospitalization of a patient with known or possible SARS-CoV disease as described in Section D below. […] Contact and AII Precautions, in addition to Standard Precautions, should be applied when caring for patients with known or possible SARS-CoV disease. […] The objective of all of the following activities is to prevent the transmission and acquisition of SARS-CoV in the hospital. […] Admit patients with SARS-CoV disease to an AIIR. […] Limit patient movement and transport outside the AIIR to medically necessary purposes. […] Limit visits to patients with known or possible SARS-CoV disease to persons who are necessary for the patients emotional well-being and care. […] Hand hygiene (i.e., hand washing or use of an alcohol-based hand rub) should be performed after contact with a patient on precautions for SARS-CoV disease or their environment of care.
  • #23 Severe Acute Respiratory Syndrome (SARS): a guide for nurses – Massachusetts Nurses Association
    https://www.massnurses.org/2003/07/15/severe-acute-respiratory-syndrome-sars-a-guide-for-nurses/
    Patients presenting with probable SARS should be moved and accommodated in: A negative pressure room with the door closed, A single room with their own bathroom, A private exam room (turn off air conditioning and open window if independent air supply is unfeasible). […] Contact your facilitys infection control personnel and initiate SARS policies and procedures as written by your healthcare facility. Unprotected exposures should be reported immediately and proper documentation completed. […] A member of the staff must be identified as the primary care provider, preferably the staff member that initiated contact with the patient upon their arrival to the facility. The designated staff member will use standard precautions (e.g., hand washing), contact precautions (e.g., use of gown and gloves) and airborne precautions (e.g., N-95 respirator and eye protection).
  • #24 Severe Acute Respiratory Syndrome (SARS): a guide for nurses – Massachusetts Nurses Association
    https://www.massnurses.org/2003/07/15/severe-acute-respiratory-syndrome-sars-a-guide-for-nurses/
    Patients presenting with probable SARS should be moved and accommodated in: A negative pressure room with the door closed, A single room with their own bathroom, A private exam room (turn off air conditioning and open window if independent air supply is unfeasible). […] Contact your facilitys infection control personnel and initiate SARS policies and procedures as written by your healthcare facility. Unprotected exposures should be reported immediately and proper documentation completed. […] A member of the staff must be identified as the primary care provider, preferably the staff member that initiated contact with the patient upon their arrival to the facility. The designated staff member will use standard precautions (e.g., hand washing), contact precautions (e.g., use of gown and gloves) and airborne precautions (e.g., N-95 respirator and eye protection).
  • #25 Nursing care of patients with severe acute respiratory syndrome in the intensive care unit: case reports in Hong Kong
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7130354/
    All patients admitted to ICU were mechanically ventilated, have more than two intravenous catheters, an arterial line, nasogastric tube (NGT) and indwelling catheter. […] Care of patients in ICU were focused not only towards providing respiratory, cardiovascular, renal, gastrointestinal support and monitoring, but most importantly, patient and family support. […] During the outbreak, our infection control protocol had to be re-visited and revised in accordance with the guidelines for infection control measures revised and released by WHO. […] The importance of infection control is vital in controlling the spread of the disease as the virus is highly contagious. […] About 60% of patients admitted to our ICU required mechanical ventilation until they can be weaned off from the ventilator.
  • #26 Nursing care of patients with severe acute respiratory syndrome in the intensive care unit: case reports in Hong Kong
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7130354/
    All patients admitted to ICU were mechanically ventilated, have more than two intravenous catheters, an arterial line, nasogastric tube (NGT) and indwelling catheter. […] Care of patients in ICU were focused not only towards providing respiratory, cardiovascular, renal, gastrointestinal support and monitoring, but most importantly, patient and family support. […] During the outbreak, our infection control protocol had to be re-visited and revised in accordance with the guidelines for infection control measures revised and released by WHO. […] The importance of infection control is vital in controlling the spread of the disease as the virus is highly contagious. […] About 60% of patients admitted to our ICU required mechanical ventilation until they can be weaned off from the ventilator.
  • #27 Nursing care of patients with severe acute respiratory syndrome in the intensive care unit: case reports in Hong Kong
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7130354/
    All patients admitted to ICU were mechanically ventilated, have more than two intravenous catheters, an arterial line, nasogastric tube (NGT) and indwelling catheter. […] Care of patients in ICU were focused not only towards providing respiratory, cardiovascular, renal, gastrointestinal support and monitoring, but most importantly, patient and family support. […] During the outbreak, our infection control protocol had to be re-visited and revised in accordance with the guidelines for infection control measures revised and released by WHO. […] The importance of infection control is vital in controlling the spread of the disease as the virus is highly contagious. […] About 60% of patients admitted to our ICU required mechanical ventilation until they can be weaned off from the ventilator.
  • #28 Nursing care of patients with severe acute respiratory syndrome in the intensive care unit: case reports in Hong Kong
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7130354/
    The care of patients on mechanical ventilation described in this paper was what was practiced in our ICU and reflected only our own experiences and available resources. […] Routine care including eye care with artificial tears, protective gel or taping the eyelids close, positioning and pressure area care were provided to the patients. […] The combination of ribavirin and corticosteroid in treating the cases in Hong Kong have stabilised and improved the outcome of most patients with most recovering from the disease after being in the critical list for nearly a month. […] Continuous public education programmes are being provided to the public through the media, websites and community group activities.
  • #29 Nursing care of patients with severe acute respiratory syndrome in the intensive care unit: case reports in Hong Kong
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7130354/
    The care of patients on mechanical ventilation described in this paper was what was practiced in our ICU and reflected only our own experiences and available resources. […] Routine care including eye care with artificial tears, protective gel or taping the eyelids close, positioning and pressure area care were provided to the patients. […] The combination of ribavirin and corticosteroid in treating the cases in Hong Kong have stabilised and improved the outcome of most patients with most recovering from the disease after being in the critical list for nearly a month. […] Continuous public education programmes are being provided to the public through the media, websites and community group activities.
  • #30 Lessons from Severe Acute Respiratory Syndrome (SARS) | RT
    https://respiratory-therapy.com/disorders-diseases/critical-care/acute-disorders/lesson-from-sars/
    Principles of infection control and ventilator management taken from the SARS epidemic may serve during future viral outbreaks. […] Twenty-five percent of patients who are diagnosed with SARS develop acute respiratory distress syndrome and will need mechanical ventilation. […] The ventilatory management of patients with SARS does not differ much from that for patients with ARDS alone. […] A low tidal volume lung protective strategy should be adopted, with the target tidal volumes at 6 mL per ideal body weight. […] High levels of positive end-expiratory pressure (PEEP) may be used to maintain a PaO2 greater than 55 mm Hg. […] Noninvasive ventilation (NIV) has been used in early acute respiratory failure to aid in ventilation and reduce intubation rates. […] SARS patients should be nursed in private rooms with a negative pressure system in the intensive care unit.
  • #31 Lessons from Severe Acute Respiratory Syndrome (SARS) | RT
    https://respiratory-therapy.com/disorders-diseases/critical-care/acute-disorders/lesson-from-sars/
    Principles of infection control and ventilator management taken from the SARS epidemic may serve during future viral outbreaks. […] Twenty-five percent of patients who are diagnosed with SARS develop acute respiratory distress syndrome and will need mechanical ventilation. […] The ventilatory management of patients with SARS does not differ much from that for patients with ARDS alone. […] A low tidal volume lung protective strategy should be adopted, with the target tidal volumes at 6 mL per ideal body weight. […] High levels of positive end-expiratory pressure (PEEP) may be used to maintain a PaO2 greater than 55 mm Hg. […] Noninvasive ventilation (NIV) has been used in early acute respiratory failure to aid in ventilation and reduce intubation rates. […] SARS patients should be nursed in private rooms with a negative pressure system in the intensive care unit.
  • #32 Treatment of severe acute respiratory syndrome
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7088345/
    Many treatment options, including antiviral agents, immunosuppressive agents, convalescent plasma, immunoglobulin, noninvasive positive pressure ventilation (NIPPV), and traditional Chinese medicine (TCM), have been introduced on the basis of different rationales. […] The application of NIPPV in SARS originates from its usefulness in the management of patients with chronic obstructive airways disease complicated by severe community-acquired pneumonia. […] NIPPV was later banned in Hong Kong because of the fear of viral spread through air leakage around the mask with aerosol generation. However, evidence does show that NIPPV is a useful and safe treatment option for SARS patients with respiratory failure, provided it is performed under good precautions and in a suitable setting. […] The use of corticosteroids may, nevertheless, be associated with enhancement of viral replication due to suppression of the innate immune response.
  • #33 Nursing Care Plan For Sars | PDF | Pneumonia | Transmission (Medicine)
    https://www.scribd.com/document/359055963/97081671-Nursing-Care-Plan-for-Sars-docx
    The nursing care plan addresses a patient diagnosed with SARS who presents with a fever, cough, and respiratory symptoms, with goals of reducing the patient’s fever and respiratory symptoms through monitoring, isolation procedures, medication administration, and health education to prevent the spread of infection to others. […] Interventions include respiratory isolation, administering antiviral medications, encouraging proper hand hygiene and coughing techniques, and ensuring the patient understands the transmission and treatment of SARS.
  • #34 Severe acute respiratory syndrome (SARS) – Symptoms, diagnosis and treatment | BMJ Best Practice
    https://bestpractice.bmj.com/topics/en-gb/904
    Initial investigations to order include FBC, aminotransferases, lactate dehydrogenase, creatine kinase, blood culture, sputum culture, nasopharyngeal virus culture, direct immunofluorescent antibody staining, chest x-ray, pulse oximetry, and reverse-transcription polymerase chain reaction (RT-PCR). […] Treatment algorithm for suspected SARS includes supportive care and monitoring of respiratory function.
  • #35 SARS | Guidance | Infection Control | Healthcare Facilities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/i-infection/healthcare.html
    SARS preparedness planning for healthcare facilities is addressed in Supplement C. One component with particular relevance to this Supplement is the education and training of healthcare workers on infection control measures. Observations of healthcare workers caring for SARS patients during the 2003 epidemic identified numerous breaches in infection control, especially in the use of personal protective equipment (PPE). These can be corrected through complete and comprehensive training, provision of properly selected PPE, and monitoring of PPE use. Most important, all healthcare settings need to re-emphasize the importance of basic infection control measures, including hand hygiene, for the control of SARS-CoV and other respiratory pathogens. […] Reinforce basic infection control practices in healthcare facilities and among healthcare personnel.
  • #36 Lessons from Severe Acute Respiratory Syndrome (SARS) | RT
    https://respiratory-therapy.com/disorders-diseases/critical-care/acute-disorders/lesson-from-sars/
    Health care workers attending to the patients wear N95 masks, protective eye wear, full face shields, caps, long-sleeved waterproof gowns, surgical gloves, and shoe covers before entering the patients room. […] A major concern for the management of SARS patients on mechanical ventilators is the protection of health care workers from the droplet transmission of the virus. […] Heated humidification is commonly used for patients on a ventilator, but during an infectious virus outbreak, a viral-bacteria heat moisture exchanger with filter properties (HMEF) should be used for humidification purposes instead. […] The strategies presented herein have been effective in containing infection of health care workers during the SARS epidemic.
  • #37 Severe Acute Respiratory Syndrome (SARS): a guide for nurses – Massachusetts Nurses Association
    https://www.massnurses.org/2003/07/15/severe-acute-respiratory-syndrome-sars-a-guide-for-nurses/
    Limit the number of staff members who are in contact with the patient. All non-essential staff, including students, should not be allowed in the unit. […] Staff should stay a minimum of 6-feet away from the patient whenever possible, and avoid exposure to droplets if close to the patient. […] Disinfectants such as fresh bleach solution (1/100) or hospital recommended cleaning agents should be widely available. Stethoscopes, scissors and other equipment have the potential to spread infection and must be properly disinfected. Linen should be rolled up and not shaken. Place used linen in a biohazard bag before sending to the laundry. […] Visitors, if allowed by the healthcare facility, should be kept to a minimum. They should be provided with personal protective equipment and supervised.
  • #38 Severe acute respiratory syndrome (SARS): MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/007192.htm
    There is no strong evidence that these treatments work well. […] Public health policies were effective at controlling outbreaks of SARS. […] Hand hygiene is the most important part of SARS prevention. Wash your hands or clean them with an alcohol-based instant hand sanitizer. […] Masks and goggles may be useful for preventing the spread of the disease. You may use gloves when handling items that may have touched infected droplets.
  • #39 About SARS – MN Dept. of Health
    https://www.health.state.mn.us/diseases/sars/basics.html
    If there is community transmission of SARS in any city in the world, the MDH will issue recommendations regarding precautions in Minnesota. We have learned that transmission of SARS was mainly among close personal contacts of ill persons and health care workers caring for them. […] In caring for a SARS patient at home strict infection control precautions should be followed. […] All persons in the household should carefully wash their hands frequently with soap or alcohol hand sanitizers, this should always be done after touching body fluids. […] SARS patients should cover their mouth and nose when coughing or sneezing or if possible wear a surgical mask when in close contact with others. […] Household members and other close contacts of SARS patients should be watched for symptoms. Household members and other close contacts of SARS patients should measure their temperature twice daily. If fever or respiratory symptoms(cough, shortness of breath or difficulty breathing) develop they should seek medical care.
  • #40 Severe Acute Respiratory Syndrome (SARS): a guide for nurses – Massachusetts Nurses Association
    https://www.massnurses.org/2003/07/15/severe-acute-respiratory-syndrome-sars-a-guide-for-nurses/
    Limit the number of staff members who are in contact with the patient. All non-essential staff, including students, should not be allowed in the unit. […] Staff should stay a minimum of 6-feet away from the patient whenever possible, and avoid exposure to droplets if close to the patient. […] Disinfectants such as fresh bleach solution (1/100) or hospital recommended cleaning agents should be widely available. Stethoscopes, scissors and other equipment have the potential to spread infection and must be properly disinfected. Linen should be rolled up and not shaken. Place used linen in a biohazard bag before sending to the laundry. […] Visitors, if allowed by the healthcare facility, should be kept to a minimum. They should be provided with personal protective equipment and supervised.
  • #41 SARS | Guidance | Infection Control | Healthcare Facilities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/i-infection/healthcare.html
    Gloves, gown, respiratory protection, and eye protection (as needed) should be donned before entering a SARS patients room or designated SARS patient-care area. […] Medical waste has not been implicated in the transmission of SARS-CoV. […] Contact with textiles has not been implicated in the transmission of SARS-CoV. […] Dishes and eating utensils have not been implicated in SARS-CoV transmission. […] Follow standard practices for handling and reprocessing used patient-care equipment, including medical devices. […] Cleaning and disinfection of environmental surfaces are important components of routine infection control in healthcare facilities. […] Because aerosol-generating procedures may pose a greater risk of SARS-CoV transmission, additional precautions are recommended for healthcare workers who perform or assist with these procedures.
  • #42 SARS | Guidance | Infection Control | Healthcare Facilities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/i-infection/healthcare.html
    Gloves, gown, respiratory protection, and eye protection (as needed) should be donned before entering a SARS patients room or designated SARS patient-care area. […] Medical waste has not been implicated in the transmission of SARS-CoV. […] Contact with textiles has not been implicated in the transmission of SARS-CoV. […] Dishes and eating utensils have not been implicated in SARS-CoV transmission. […] Follow standard practices for handling and reprocessing used patient-care equipment, including medical devices. […] Cleaning and disinfection of environmental surfaces are important components of routine infection control in healthcare facilities. […] Because aerosol-generating procedures may pose a greater risk of SARS-CoV transmission, additional precautions are recommended for healthcare workers who perform or assist with these procedures.
  • #43 Severe acute respiratory syndrome (SARS): MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/007192.htm
    Severe acute respiratory syndrome (SARS) is a serious form of pneumonia. Infection with the SARS virus causes acute respiratory distress (severe breathing difficulty), and sometimes death. […] People who are thought to have SARS should be checked right away by a provider. If they are suspected of having SARS, they should be kept isolated in a hospital. […] Treatment may include: Antibiotics to treat bacteria that cause pneumonia (until bacterial pneumonia is ruled out or if there is bacterial pneumonia in addition to SARS) and to treat bacterial infections that could occur in addition to SARS and Oxygen, breathing support (mechanical ventilation), or chest therapy. […] In some serious cases, the liquid part of blood from people who have already recovered from SARS has been given as a treatment.
  • #44 Department of Health | Communicable Disease Service | Severe Acute Respiratory Syndrome (SARS)
    https://www.nj.gov/health/cd/topics/sars.shtml
    Health care providers, administrators, and clinical laboratory directors should report confirmed or suspect cases immediately to their Local Health Department by telephone. […] Severe acute respiratory syndrome (SARS) is a viral respiratory illness that was recognized as a global threat in March 2003. […] The disease is spread by close person-to-person contact, such as caring for, living with or having direct contact with an infected person. […] Symptoms of SARS can vary, but may include high fever, chills, headache, body aches, pneumonia, diarrhea, dry cough, low levels of oxygen in the blood. […] No single medicine can effectively treat SARS. […] Different types of treatment regimens have been used for people who are severely ill and hospitalized including antibiotics, antivirals and steroids.
  • #45 Severe acute respiratory syndrome (SARS): MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/007192.htm
    Severe acute respiratory syndrome (SARS) is a serious form of pneumonia. Infection with the SARS virus causes acute respiratory distress (severe breathing difficulty), and sometimes death. […] People who are thought to have SARS should be checked right away by a provider. If they are suspected of having SARS, they should be kept isolated in a hospital. […] Treatment may include: Antibiotics to treat bacteria that cause pneumonia (until bacterial pneumonia is ruled out or if there is bacterial pneumonia in addition to SARS) and to treat bacterial infections that could occur in addition to SARS and Oxygen, breathing support (mechanical ventilation), or chest therapy. […] In some serious cases, the liquid part of blood from people who have already recovered from SARS has been given as a treatment.
  • #46 Severe acute respiratory syndrome (SARS) – Diagnosis & treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/sars/diagnosis-treatment/drc-20351771
    Hospital care for SARS involves easing symptoms while the SARS virus runs its course. Care might include receiving fluids through a vein and extra oxygen if needed.
  • #47 Treatment of severe acute respiratory syndrome
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7088345/
    The best treatment strategy for severe acute respiratory syndrome (SARS) is still unknown. Ribavirin and corticosteroids were used extensively during the SARS outbreak. Ribavirin has been criticized for its lack of efficacy. Corticosteroids are effective in lowering the fever and reversing changes in the chest radiograph but have the caveat of encouraging viral replication. The effectiveness of corticosteroids has only been suggested by uncontrolled observations, and the role of these agents in therapy remains to be established by randomized controlled studies. Both ribavirin and corticosteroids have very significant side effects. The lopinavir/ritonavir combination has been shown to reduce the intubation rate and the incidence of adverse clinical outcomes when used with ribavirin. When patients deteriorate clinically despite treatment with ribavirin and corticosteroids, rescue treatment with convalescent plasma and immunoglobulin may be beneficial. Noninvasive positive pressure ventilation is a sound treatment for SARS patients with respiratory failure if administered with due precaution in the correct environment. Interferons and other novel agents may hold promise as useful anti-SARS therapies in the future. The experience with traditional Chinese medicine is encouraging, and its use as an adjuvant should be further investigated.
  • #48 Treatment of severe acute respiratory syndrome
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7088345/
    The best treatment strategy for severe acute respiratory syndrome (SARS) is still unknown. Ribavirin and corticosteroids were used extensively during the SARS outbreak. Ribavirin has been criticized for its lack of efficacy. Corticosteroids are effective in lowering the fever and reversing changes in the chest radiograph but have the caveat of encouraging viral replication. The effectiveness of corticosteroids has only been suggested by uncontrolled observations, and the role of these agents in therapy remains to be established by randomized controlled studies. Both ribavirin and corticosteroids have very significant side effects. The lopinavir/ritonavir combination has been shown to reduce the intubation rate and the incidence of adverse clinical outcomes when used with ribavirin. When patients deteriorate clinically despite treatment with ribavirin and corticosteroids, rescue treatment with convalescent plasma and immunoglobulin may be beneficial. Noninvasive positive pressure ventilation is a sound treatment for SARS patients with respiratory failure if administered with due precaution in the correct environment. Interferons and other novel agents may hold promise as useful anti-SARS therapies in the future. The experience with traditional Chinese medicine is encouraging, and its use as an adjuvant should be further investigated.
  • #49 Treatment of severe acute respiratory syndrome
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7088345/
    The best treatment strategy for severe acute respiratory syndrome (SARS) is still unknown. Ribavirin and corticosteroids were used extensively during the SARS outbreak. Ribavirin has been criticized for its lack of efficacy. Corticosteroids are effective in lowering the fever and reversing changes in the chest radiograph but have the caveat of encouraging viral replication. The effectiveness of corticosteroids has only been suggested by uncontrolled observations, and the role of these agents in therapy remains to be established by randomized controlled studies. Both ribavirin and corticosteroids have very significant side effects. The lopinavir/ritonavir combination has been shown to reduce the intubation rate and the incidence of adverse clinical outcomes when used with ribavirin. When patients deteriorate clinically despite treatment with ribavirin and corticosteroids, rescue treatment with convalescent plasma and immunoglobulin may be beneficial. Noninvasive positive pressure ventilation is a sound treatment for SARS patients with respiratory failure if administered with due precaution in the correct environment. Interferons and other novel agents may hold promise as useful anti-SARS therapies in the future. The experience with traditional Chinese medicine is encouraging, and its use as an adjuvant should be further investigated.
  • #50 Treatment of severe acute respiratory syndrome
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7088345/
    The best treatment strategy for severe acute respiratory syndrome (SARS) is still unknown. Ribavirin and corticosteroids were used extensively during the SARS outbreak. Ribavirin has been criticized for its lack of efficacy. Corticosteroids are effective in lowering the fever and reversing changes in the chest radiograph but have the caveat of encouraging viral replication. The effectiveness of corticosteroids has only been suggested by uncontrolled observations, and the role of these agents in therapy remains to be established by randomized controlled studies. Both ribavirin and corticosteroids have very significant side effects. The lopinavir/ritonavir combination has been shown to reduce the intubation rate and the incidence of adverse clinical outcomes when used with ribavirin. When patients deteriorate clinically despite treatment with ribavirin and corticosteroids, rescue treatment with convalescent plasma and immunoglobulin may be beneficial. Noninvasive positive pressure ventilation is a sound treatment for SARS patients with respiratory failure if administered with due precaution in the correct environment. Interferons and other novel agents may hold promise as useful anti-SARS therapies in the future. The experience with traditional Chinese medicine is encouraging, and its use as an adjuvant should be further investigated.
  • #51 Treatment of severe acute respiratory syndrome
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7088345/
    The use of corticosteroids in SARS, especially at high doses and for prolonged periods, has been accompanied by significant side effects. These include hyperglycemia, hypokalemia, hypertension, gastrointestinal hemorrhage, and, in particular, nosocomial infections. […] Avascular necrosis of bone, or osteonecrosis, is probably one the most distressing complications associated with the use of corticosteroids in SARS. […] In patients who deteriorated irrevocably despite receiving pulse methylprednisolone, convalescent plasma, obtained from patients who recovered from SARS, had been used as a last resort. […] Another form of salvage therapy for patients who run a relentless downhill course is intravenous immunoglobulin (IVIG) or pentaglobin infusion. […] The present therapy of SARS is less than satisfactory, and much effort has been expended in looking for novel treatment modalities.
  • #52 Treatment of severe acute respiratory syndrome
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7088345/
    The use of corticosteroids in SARS, especially at high doses and for prolonged periods, has been accompanied by significant side effects. These include hyperglycemia, hypokalemia, hypertension, gastrointestinal hemorrhage, and, in particular, nosocomial infections. […] Avascular necrosis of bone, or osteonecrosis, is probably one the most distressing complications associated with the use of corticosteroids in SARS. […] In patients who deteriorated irrevocably despite receiving pulse methylprednisolone, convalescent plasma, obtained from patients who recovered from SARS, had been used as a last resort. […] Another form of salvage therapy for patients who run a relentless downhill course is intravenous immunoglobulin (IVIG) or pentaglobin infusion. […] The present therapy of SARS is less than satisfactory, and much effort has been expended in looking for novel treatment modalities.
  • #53 Treatment of severe acute respiratory syndrome
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7088345/
    The best treatment strategy for severe acute respiratory syndrome (SARS) is still unknown. Ribavirin and corticosteroids were used extensively during the SARS outbreak. Ribavirin has been criticized for its lack of efficacy. Corticosteroids are effective in lowering the fever and reversing changes in the chest radiograph but have the caveat of encouraging viral replication. The effectiveness of corticosteroids has only been suggested by uncontrolled observations, and the role of these agents in therapy remains to be established by randomized controlled studies. Both ribavirin and corticosteroids have very significant side effects. The lopinavir/ritonavir combination has been shown to reduce the intubation rate and the incidence of adverse clinical outcomes when used with ribavirin. When patients deteriorate clinically despite treatment with ribavirin and corticosteroids, rescue treatment with convalescent plasma and immunoglobulin may be beneficial. Noninvasive positive pressure ventilation is a sound treatment for SARS patients with respiratory failure if administered with due precaution in the correct environment. Interferons and other novel agents may hold promise as useful anti-SARS therapies in the future. The experience with traditional Chinese medicine is encouraging, and its use as an adjuvant should be further investigated.
  • #54 Treatment of severe acute respiratory syndrome
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7088345/
    During the SARS outbreak, traditional Chinese medicine (TCM) was used extensively in China. […] A number of treatment protocols were reported in Hong Kong during the SARS outbreak. […] Ribavirin and corticosteroids were the cornerstones of treatment during the SARS outbreak. Ribavirin has shown a lack of efficacy in a number of studies. The usefulness of corticosteroids has been reported in some uncontrolled trials, but further investigations are required. The antiretroviral formulation of lopinavir/ritonavir, when used with ribavirin, was found to be associated with clinical benefits. […] Finally, the optimal treatment regimen for SARS remains elusive. Randomized controlled treatment trials should be done, especially through international collaboration, to discover the best form of therapy.
  • #55 Severe acute respiratory syndrome (SARS): MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/007192.htm
    There is no strong evidence that these treatments work well. […] Public health policies were effective at controlling outbreaks of SARS. […] Hand hygiene is the most important part of SARS prevention. Wash your hands or clean them with an alcohol-based instant hand sanitizer. […] Masks and goggles may be useful for preventing the spread of the disease. You may use gloves when handling items that may have touched infected droplets.
  • #56 Treatment of severe acute respiratory syndrome
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7088345/
    During the SARS outbreak, traditional Chinese medicine (TCM) was used extensively in China. […] A number of treatment protocols were reported in Hong Kong during the SARS outbreak. […] Ribavirin and corticosteroids were the cornerstones of treatment during the SARS outbreak. Ribavirin has shown a lack of efficacy in a number of studies. The usefulness of corticosteroids has been reported in some uncontrolled trials, but further investigations are required. The antiretroviral formulation of lopinavir/ritonavir, when used with ribavirin, was found to be associated with clinical benefits. […] Finally, the optimal treatment regimen for SARS remains elusive. Randomized controlled treatment trials should be done, especially through international collaboration, to discover the best form of therapy.
  • #57 Severe acute respiratory syndrome (SARS) – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/sars/symptoms-causes/syc-20351765
    SARS is a serious illness that can lead to death. If you have any symptoms of a respiratory infection, call a member of your healthcare team right away. […] Many people with SARS get pneumonia. And sometimes, a machine called a ventilator is needed to help with breathing. SARS is fatal in some cases, often because the body cant get enough oxygen or cant remove enough carbon dioxide. This condition is called respiratory failure. […] Researchers are working on various vaccines for SARS. But none has been tested in humans. If infections caused by the SARS virus happen again, follow some safety measures. The following tips are key if you care for someone who may have SARS: […] Follow these steps for at least 10 days after the persons fever has gone away and any breathing symptoms have gotten better. The Centers for Disease Control and Prevention recommends that an infected person stay home from work or school during this time. Call your healthcare team right away if a fever or other symptoms start within 10 days of close contact with someone who has SARS.
  • #58 Treatment of severe acute respiratory syndrome
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7088345/
    The use of corticosteroids in SARS, especially at high doses and for prolonged periods, has been accompanied by significant side effects. These include hyperglycemia, hypokalemia, hypertension, gastrointestinal hemorrhage, and, in particular, nosocomial infections. […] Avascular necrosis of bone, or osteonecrosis, is probably one the most distressing complications associated with the use of corticosteroids in SARS. […] In patients who deteriorated irrevocably despite receiving pulse methylprednisolone, convalescent plasma, obtained from patients who recovered from SARS, had been used as a last resort. […] Another form of salvage therapy for patients who run a relentless downhill course is intravenous immunoglobulin (IVIG) or pentaglobin infusion. […] The present therapy of SARS is less than satisfactory, and much effort has been expended in looking for novel treatment modalities.
  • #59 Treatment of severe acute respiratory syndrome
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7088345/
    The use of corticosteroids in SARS, especially at high doses and for prolonged periods, has been accompanied by significant side effects. These include hyperglycemia, hypokalemia, hypertension, gastrointestinal hemorrhage, and, in particular, nosocomial infections. […] Avascular necrosis of bone, or osteonecrosis, is probably one the most distressing complications associated with the use of corticosteroids in SARS. […] In patients who deteriorated irrevocably despite receiving pulse methylprednisolone, convalescent plasma, obtained from patients who recovered from SARS, had been used as a last resort. […] Another form of salvage therapy for patients who run a relentless downhill course is intravenous immunoglobulin (IVIG) or pentaglobin infusion. […] The present therapy of SARS is less than satisfactory, and much effort has been expended in looking for novel treatment modalities.
  • #60 Nursing Care Plan For Sars | PDF | Pneumonia | Transmission (Medicine)
    https://www.scribd.com/document/359055963/97081671-Nursing-Care-Plan-for-Sars-docx
    The nursing care plan addresses a patient diagnosed with SARS who presents with a fever, cough, and respiratory symptoms, with goals of reducing the patient’s fever and respiratory symptoms through monitoring, isolation procedures, medication administration, and health education to prevent the spread of infection to others. […] Interventions include respiratory isolation, administering antiviral medications, encouraging proper hand hygiene and coughing techniques, and ensuring the patient understands the transmission and treatment of SARS.
  • #61 Nursing care of patients with severe acute respiratory syndrome in the intensive care unit: case reports in Hong Kong
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7130354/
    All patients admitted to ICU were mechanically ventilated, have more than two intravenous catheters, an arterial line, nasogastric tube (NGT) and indwelling catheter. […] Care of patients in ICU were focused not only towards providing respiratory, cardiovascular, renal, gastrointestinal support and monitoring, but most importantly, patient and family support. […] During the outbreak, our infection control protocol had to be re-visited and revised in accordance with the guidelines for infection control measures revised and released by WHO. […] The importance of infection control is vital in controlling the spread of the disease as the virus is highly contagious. […] About 60% of patients admitted to our ICU required mechanical ventilation until they can be weaned off from the ventilator.
  • #62 SARS | Guidance | Infection Control | Healthcare Facilities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/i-infection/healthcare.html
    Follow recommended precautions for hospitalization of a patient with known or possible SARS-CoV disease as described in Section D below. […] Contact and AII Precautions, in addition to Standard Precautions, should be applied when caring for patients with known or possible SARS-CoV disease. […] The objective of all of the following activities is to prevent the transmission and acquisition of SARS-CoV in the hospital. […] Admit patients with SARS-CoV disease to an AIIR. […] Limit patient movement and transport outside the AIIR to medically necessary purposes. […] Limit visits to patients with known or possible SARS-CoV disease to persons who are necessary for the patients emotional well-being and care. […] Hand hygiene (i.e., hand washing or use of an alcohol-based hand rub) should be performed after contact with a patient on precautions for SARS-CoV disease or their environment of care.
  • #63 Nursing Care Plan For Sars | PDF | Pneumonia | Transmission (Medicine)
    https://www.scribd.com/document/359055963/97081671-Nursing-Care-Plan-for-Sars-docx
    The nursing care plan addresses a patient diagnosed with SARS who presents with a fever, cough, and respiratory symptoms, with goals of reducing the patient’s fever and respiratory symptoms through monitoring, isolation procedures, medication administration, and health education to prevent the spread of infection to others. […] Interventions include respiratory isolation, administering antiviral medications, encouraging proper hand hygiene and coughing techniques, and ensuring the patient understands the transmission and treatment of SARS.
  • #64 Severe acute respiratory syndrome (SARS) – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/sars/symptoms-causes/syc-20351765
    SARS is a serious illness that can lead to death. If you have any symptoms of a respiratory infection, call a member of your healthcare team right away. […] Many people with SARS get pneumonia. And sometimes, a machine called a ventilator is needed to help with breathing. SARS is fatal in some cases, often because the body cant get enough oxygen or cant remove enough carbon dioxide. This condition is called respiratory failure. […] Researchers are working on various vaccines for SARS. But none has been tested in humans. If infections caused by the SARS virus happen again, follow some safety measures. The following tips are key if you care for someone who may have SARS: […] Follow these steps for at least 10 days after the persons fever has gone away and any breathing symptoms have gotten better. The Centers for Disease Control and Prevention recommends that an infected person stay home from work or school during this time. Call your healthcare team right away if a fever or other symptoms start within 10 days of close contact with someone who has SARS.
  • #65 Severe Acute Respiratory Syndrome (SARS): Care Instructions | Kaiser Permanente
    https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.severe-acute-respiratory-syndrome-sars-care-instructions.uf9043
    Severe acute respiratory syndrome (SARS) is an illness that first infected people in Asia, North America, and Europe in 2002. It causes a fever, muscle aches, and a sore throat. Some people also get a dry cough or diarrhea. Most people get pneumonia. In some cases, these symptoms get worse very quickly. […] Severe SARS can be very serious. For this reason, it is usually treated in the hospital. With treatment, most people recover. […] Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It’s also a good idea to know your test results and keep a list of the medicines you take. […] Call your doctor now or seek immediate medical care if: You have symptoms of SARS and you were in an area with a SARS outbreak. […] Watch closely for changes in your health, and be sure to contact your doctor if: You do not get better as expected.
  • #66 Severe Acute Respiratory Syndrome (SARS): Care Instructions | Kaiser Permanente
    https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.severe-acute-respiratory-syndrome-sars-care-instructions.uf9043
    Severe acute respiratory syndrome (SARS) is an illness that first infected people in Asia, North America, and Europe in 2002. It causes a fever, muscle aches, and a sore throat. Some people also get a dry cough or diarrhea. Most people get pneumonia. In some cases, these symptoms get worse very quickly. […] Severe SARS can be very serious. For this reason, it is usually treated in the hospital. With treatment, most people recover. […] Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It’s also a good idea to know your test results and keep a list of the medicines you take. […] Call your doctor now or seek immediate medical care if: You have symptoms of SARS and you were in an area with a SARS outbreak. […] Watch closely for changes in your health, and be sure to contact your doctor if: You do not get better as expected.
  • #67 SARS | Guidance | Recommendations for Preparedness and Response Activities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/c-healthcare/recommended.html
    As with any disease control effort, surveillance for cases of SARS-CoV disease is the basis for control. SARS case surveillance, including surveillance in healthcare facilities, is also discussed in Supplement B and in the SARS response matrices for healthcare facilities (Appendix C1). Some key surveillance activities specific to healthcare facilities are described below. […] SARS highlights the risks of nosocomial transmission of respiratory pathogens and provides an opportunity to improve overall infection control in healthcare facilities. During the 2003 epidemic, public health authorities quickly recognized infection control as a primary means for containing SARS-CoV. All healthcare facilities need to re-emphasize the importance of basic infection control measures for the control of SARS-CoV transmission.
  • #68 SARS | Guidance | Recommendations for Preparedness and Response Activities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/c-healthcare/recommended.html
    Appropriate patient placement is a significant component of effective SARS control. Each healthcare facility should develop a strategy and procedures to: 1) quickly separate potential SARS patients from other patients, and 2) implement appropriate isolation precautions. […] Although most SARS-CoV transmission appears to occur through droplet and contact exposures, transmission by fomites and by the airborne route remain possibilities. Therefore, patients who require hospitalization should be admitted to an Airborne Infection Isolation room (AIIR) or specially adapted SARS unit or ward where they can be managed safely. […] Unrecognized patients were a significant source of transmission during the 2003 SARS outbreak. Thus, rapid reporting and evaluation of persons exposed to SARS-CoV will be an important measure in early identification and isolation.
  • #69 SARS | Guidance | Infection Control | Healthcare Facilities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/i-infection/healthcare.html
    Follow recommended precautions for hospitalization of a patient with known or possible SARS-CoV disease as described in Section D below. […] Contact and AII Precautions, in addition to Standard Precautions, should be applied when caring for patients with known or possible SARS-CoV disease. […] The objective of all of the following activities is to prevent the transmission and acquisition of SARS-CoV in the hospital. […] Admit patients with SARS-CoV disease to an AIIR. […] Limit patient movement and transport outside the AIIR to medically necessary purposes. […] Limit visits to patients with known or possible SARS-CoV disease to persons who are necessary for the patients emotional well-being and care. […] Hand hygiene (i.e., hand washing or use of an alcohol-based hand rub) should be performed after contact with a patient on precautions for SARS-CoV disease or their environment of care.
  • #70 Information Regarding Severe Acute Respiratory Syndrome (SARS) | Occupational Safety and Health Administration
    https://www.osha.gov/emergency-preparedness/sars
    OSHA has developed this Information Regarding Severe Acute Respiratory Syndrome (SARS) to provide relevant and timely information regarding this illness to employers, employees, and other interested parties. […] The CDC has reported very few cases of occupationally acquired SARS in the United States. The CDC is working in collaboration with state and local health departments to develop a systematic approach to survey SARS exposures and infection in healthcare workers. The CDC has issued a number of recommendations for healthcare workers who may have contact with a suspected SARS patient. […] Since the infectivity and route of transmission of SARS are unknown, healthcare workers treating patients known to be infected with SARS should use standard precautions, including good work and hygiene practices and the use of personal protective equipment (PPE) appropriate for bloodborne and airborne exposures.
  • #71 Lessons from Severe Acute Respiratory Syndrome (SARS) | RT
    https://respiratory-therapy.com/disorders-diseases/critical-care/acute-disorders/lesson-from-sars/
    Health care workers attending to the patients wear N95 masks, protective eye wear, full face shields, caps, long-sleeved waterproof gowns, surgical gloves, and shoe covers before entering the patients room. […] A major concern for the management of SARS patients on mechanical ventilators is the protection of health care workers from the droplet transmission of the virus. […] Heated humidification is commonly used for patients on a ventilator, but during an infectious virus outbreak, a viral-bacteria heat moisture exchanger with filter properties (HMEF) should be used for humidification purposes instead. […] The strategies presented herein have been effective in containing infection of health care workers during the SARS epidemic.
  • #72 Information Regarding Severe Acute Respiratory Syndrome (SARS) | Occupational Safety and Health Administration
    https://www.osha.gov/emergency-preparedness/sars
    Laboratory personnel in facilities performing diagnostic tests on patients suspected to be infected with SARS should follow biosafety preventive measures established by the CDC, Severe Acute Respiratory Syndrome (SARS) – Laboratory Biosafety. […] The CDC has published interim recommendations to protect employees who may be required to transport patients with SARS by air: Guidance on Air Medical Transport for SARS Patients. […] The CDC provides recommendations for those handling human remains of SARS patients. […] All employees with potential occupational exposure to SARS, as described in this document, should be trained on the hazards associated with that exposure and on the protocols in place in their facilities to isolate and report cases and to reduce exposures. […] If an employee experiences a fever and respiratory symptoms after contact with a patient known to be infected with SARS, the CDC recommends that the employee be excluded from duty.
  • #73 SARS | Guidance | Infection Control | Healthcare Facilities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/i-infection/healthcare.html
    Gloves, gown, respiratory protection, and eye protection (as needed) should be donned before entering a SARS patients room or designated SARS patient-care area. […] Medical waste has not been implicated in the transmission of SARS-CoV. […] Contact with textiles has not been implicated in the transmission of SARS-CoV. […] Dishes and eating utensils have not been implicated in SARS-CoV transmission. […] Follow standard practices for handling and reprocessing used patient-care equipment, including medical devices. […] Cleaning and disinfection of environmental surfaces are important components of routine infection control in healthcare facilities. […] Because aerosol-generating procedures may pose a greater risk of SARS-CoV transmission, additional precautions are recommended for healthcare workers who perform or assist with these procedures.
  • #74 Lessons from Severe Acute Respiratory Syndrome (SARS) | RT
    https://respiratory-therapy.com/disorders-diseases/critical-care/acute-disorders/lesson-from-sars/
    Health care workers attending to the patients wear N95 masks, protective eye wear, full face shields, caps, long-sleeved waterproof gowns, surgical gloves, and shoe covers before entering the patients room. […] A major concern for the management of SARS patients on mechanical ventilators is the protection of health care workers from the droplet transmission of the virus. […] Heated humidification is commonly used for patients on a ventilator, but during an infectious virus outbreak, a viral-bacteria heat moisture exchanger with filter properties (HMEF) should be used for humidification purposes instead. […] The strategies presented herein have been effective in containing infection of health care workers during the SARS epidemic.
  • #75 SARS | Guidance | Recommendations for Preparedness and Response Activities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/c-healthcare/recommended.html
    A SARS outbreak challenges a healthcare facility’s ability to meet staffing, organizational, and resource needs. During an outbreak of any size, existing staffing shortages may be amplified by illness among staff members, fear and concern about SARS, and isolation and quarantine of exposed staff or ill/exposed family members. […] When SARS-CoV is present in the community surrounding a healthcare facility, preventing unrecognized SARS patients from entering the facility will be essential. Appropriate surveillance and screening measures are detailed in the surveillance section of this document and in Supplement B. Restricting access to the facility will increase the efficacy of surveillance and screening measures. […] SARS patient care requires both consumable (e.g., PPE) and durable (e.g., ventilators) supplies. Experience in other countries indicates that a SARS outbreak not only can strain a facility’s supply of these resources but also can affect the ability to order replacement supplies.
  • #76 SARS | Guidance | Recommendations for Preparedness and Response Activities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/c-healthcare/recommended.html
    A SARS outbreak challenges a healthcare facility’s ability to meet staffing, organizational, and resource needs. During an outbreak of any size, existing staffing shortages may be amplified by illness among staff members, fear and concern about SARS, and isolation and quarantine of exposed staff or ill/exposed family members. […] When SARS-CoV is present in the community surrounding a healthcare facility, preventing unrecognized SARS patients from entering the facility will be essential. Appropriate surveillance and screening measures are detailed in the surveillance section of this document and in Supplement B. Restricting access to the facility will increase the efficacy of surveillance and screening measures. […] SARS patient care requires both consumable (e.g., PPE) and durable (e.g., ventilators) supplies. Experience in other countries indicates that a SARS outbreak not only can strain a facility’s supply of these resources but also can affect the ability to order replacement supplies.
  • #77 SARS | Guidance | Recommendations for Preparedness and Response Activities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/c-healthcare/recommended.html
    A SARS outbreak will generate a need for rapid analysis of the status of patients and transmission in the healthcare facility and reporting of this information to public health officials and to the public, press, and political leaders. These needs can overwhelm resources that are essential to other response activities.
  • #78 Severe acute respiratory syndrome (SARS)
    https://www.health.vic.gov.au/infectious-diseases/severe-acute-respiratory-syndrome-sars
    In the setting of a SARS outbreak, the diagnosis should be considered for almost any change in health status, even in the absence of typical clinical features of SARS, when such patients have epidemiological risk factors for SARS (for example, close contact with someone suspected to have SARS, or exposure to a location [domestic or international] with documented or suspected recent transmission of SARS CoV). […] Once there exists an index of suspicion of SARS, the appropriate infection control measures need to be activated and suitable personal protective equipment (PPE) worn. […] Suspected cases will be managed on their clinical merits, with home care regarded as a suitable option if the domestic situation, including its suitability in terms of infection control, is judged to be adequate. In such circumstances, cases will be advised to voluntarily restrict their movements.
  • #79 About SARS – MN Dept. of Health
    https://www.health.state.mn.us/diseases/sars/basics.html
    If there is community transmission of SARS in any city in the world, the MDH will issue recommendations regarding precautions in Minnesota. We have learned that transmission of SARS was mainly among close personal contacts of ill persons and health care workers caring for them. […] In caring for a SARS patient at home strict infection control precautions should be followed. […] All persons in the household should carefully wash their hands frequently with soap or alcohol hand sanitizers, this should always be done after touching body fluids. […] SARS patients should cover their mouth and nose when coughing or sneezing or if possible wear a surgical mask when in close contact with others. […] Household members and other close contacts of SARS patients should be watched for symptoms. Household members and other close contacts of SARS patients should measure their temperature twice daily. If fever or respiratory symptoms(cough, shortness of breath or difficulty breathing) develop they should seek medical care.
  • #80 About SARS – MN Dept. of Health
    https://www.health.state.mn.us/diseases/sars/basics.html
    If there is community transmission of SARS in any city in the world, the MDH will issue recommendations regarding precautions in Minnesota. We have learned that transmission of SARS was mainly among close personal contacts of ill persons and health care workers caring for them. […] In caring for a SARS patient at home strict infection control precautions should be followed. […] All persons in the household should carefully wash their hands frequently with soap or alcohol hand sanitizers, this should always be done after touching body fluids. […] SARS patients should cover their mouth and nose when coughing or sneezing or if possible wear a surgical mask when in close contact with others. […] Household members and other close contacts of SARS patients should be watched for symptoms. Household members and other close contacts of SARS patients should measure their temperature twice daily. If fever or respiratory symptoms(cough, shortness of breath or difficulty breathing) develop they should seek medical care.
  • #81 Severe acute respiratory syndrome (SARS) – Health New Zealand | Te Whatu Ora
    https://www.tewhatuora.govt.nz/for-health-professionals/clinical-guidance/communicable-disease-control-manual/severe-acute-respiratory-syndrome-sars
    Recommend voluntary isolation at home and record temperature daily for 10 days following contact. Ensure contact is visited or telephoned daily by a member of the public health service to determine whether fever or other symptoms of SARS-CoV infection are developing. Clinical evidence of SARS in a contact requires immediate clinical assessment and isolation. […] Advise all contacts of the incubation period and typical symptoms of SARS-CoV infection. Encourage them to seek early medical attention if symptoms develop.
  • #82 Severe acute respiratory syndrome (SARS) – Health New Zealand | Te Whatu Ora
    https://www.tewhatuora.govt.nz/for-health-professionals/clinical-guidance/communicable-disease-control-manual/severe-acute-respiratory-syndrome-sars
    Recommend voluntary isolation at home and record temperature daily for 10 days following contact. Ensure contact is visited or telephoned daily by a member of the public health service to determine whether fever or other symptoms of SARS-CoV infection are developing. Clinical evidence of SARS in a contact requires immediate clinical assessment and isolation. […] Advise all contacts of the incubation period and typical symptoms of SARS-CoV infection. Encourage them to seek early medical attention if symptoms develop.
  • #83 About SARS – MN Dept. of Health
    https://www.health.state.mn.us/diseases/sars/basics.html
    Severe acute respiratory syndrome (SARS) is a viral respiratory illness that first emerged in China in November 2002, and later spread through international travel to 29 countries worldwide causing large outbreaks in Hong Kong; Taiwan; Singapore; Hanoi, Vietnam; and Toronto, Canada. […] Most of the U.S. SARS cases were among travelers returning from other parts of the world with SARS. […] SARS is spread primarily by close person-to-person contact. In the context of SARS, close contact means having cared for or lived with someone with SARS or having direct contact with respiratory secretions or body fluids of a patient with SARS. […] For a severe respiratory illness to be SARS, there has to be a history of travel to a SARS affected area or close personal contact with a person with SARS, within ten days before symptoms start, this is called the epidemiological link.
  • #84 SARS | Guidance | Infection Control | Healthcare Facilities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/i-infection/healthcare.html
    SARS preparedness planning for healthcare facilities is addressed in Supplement C. One component with particular relevance to this Supplement is the education and training of healthcare workers on infection control measures. Observations of healthcare workers caring for SARS patients during the 2003 epidemic identified numerous breaches in infection control, especially in the use of personal protective equipment (PPE). These can be corrected through complete and comprehensive training, provision of properly selected PPE, and monitoring of PPE use. Most important, all healthcare settings need to re-emphasize the importance of basic infection control measures, including hand hygiene, for the control of SARS-CoV and other respiratory pathogens. […] Reinforce basic infection control practices in healthcare facilities and among healthcare personnel.
  • #85 SARS | Guidance | Infection Control | Healthcare Facilities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/i-infection/healthcare.html
    SARS preparedness planning for healthcare facilities is addressed in Supplement C. One component with particular relevance to this Supplement is the education and training of healthcare workers on infection control measures. Observations of healthcare workers caring for SARS patients during the 2003 epidemic identified numerous breaches in infection control, especially in the use of personal protective equipment (PPE). These can be corrected through complete and comprehensive training, provision of properly selected PPE, and monitoring of PPE use. Most important, all healthcare settings need to re-emphasize the importance of basic infection control measures, including hand hygiene, for the control of SARS-CoV and other respiratory pathogens. […] Reinforce basic infection control practices in healthcare facilities and among healthcare personnel.
  • #86 SARS | Guidance | Infection Control | Healthcare Facilities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/i-infection/healthcare.html
    SARS preparedness planning for healthcare facilities is addressed in Supplement C. One component with particular relevance to this Supplement is the education and training of healthcare workers on infection control measures. Observations of healthcare workers caring for SARS patients during the 2003 epidemic identified numerous breaches in infection control, especially in the use of personal protective equipment (PPE). These can be corrected through complete and comprehensive training, provision of properly selected PPE, and monitoring of PPE use. Most important, all healthcare settings need to re-emphasize the importance of basic infection control measures, including hand hygiene, for the control of SARS-CoV and other respiratory pathogens. […] Reinforce basic infection control practices in healthcare facilities and among healthcare personnel.
  • #87 Information Regarding Severe Acute Respiratory Syndrome (SARS) | Occupational Safety and Health Administration
    https://www.osha.gov/emergency-preparedness/sars
    Laboratory personnel in facilities performing diagnostic tests on patients suspected to be infected with SARS should follow biosafety preventive measures established by the CDC, Severe Acute Respiratory Syndrome (SARS) – Laboratory Biosafety. […] The CDC has published interim recommendations to protect employees who may be required to transport patients with SARS by air: Guidance on Air Medical Transport for SARS Patients. […] The CDC provides recommendations for those handling human remains of SARS patients. […] All employees with potential occupational exposure to SARS, as described in this document, should be trained on the hazards associated with that exposure and on the protocols in place in their facilities to isolate and report cases and to reduce exposures. […] If an employee experiences a fever and respiratory symptoms after contact with a patient known to be infected with SARS, the CDC recommends that the employee be excluded from duty.
  • #88 SARS | Guidance | Recommendations for Preparedness and Response Activities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/c-healthcare/recommended.html
    Appropriate patient placement is a significant component of effective SARS control. Each healthcare facility should develop a strategy and procedures to: 1) quickly separate potential SARS patients from other patients, and 2) implement appropriate isolation precautions. […] Although most SARS-CoV transmission appears to occur through droplet and contact exposures, transmission by fomites and by the airborne route remain possibilities. Therefore, patients who require hospitalization should be admitted to an Airborne Infection Isolation room (AIIR) or specially adapted SARS unit or ward where they can be managed safely. […] Unrecognized patients were a significant source of transmission during the 2003 SARS outbreak. Thus, rapid reporting and evaluation of persons exposed to SARS-CoV will be an important measure in early identification and isolation.
  • #89 SARS | Guidance | Recommendations for Preparedness and Response Activities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/c-healthcare/recommended.html
    Appropriate patient placement is a significant component of effective SARS control. Each healthcare facility should develop a strategy and procedures to: 1) quickly separate potential SARS patients from other patients, and 2) implement appropriate isolation precautions. […] Although most SARS-CoV transmission appears to occur through droplet and contact exposures, transmission by fomites and by the airborne route remain possibilities. Therefore, patients who require hospitalization should be admitted to an Airborne Infection Isolation room (AIIR) or specially adapted SARS unit or ward where they can be managed safely. […] Unrecognized patients were a significant source of transmission during the 2003 SARS outbreak. Thus, rapid reporting and evaluation of persons exposed to SARS-CoV will be an important measure in early identification and isolation.
  • #90 SARS | Guidance | Recommendations for Preparedness and Response Activities | CDC
    https://archive.cdc.gov/www_cdc_gov/sars/guidance/c-healthcare/recommended.html
    A SARS outbreak challenges a healthcare facility’s ability to meet staffing, organizational, and resource needs. During an outbreak of any size, existing staffing shortages may be amplified by illness among staff members, fear and concern about SARS, and isolation and quarantine of exposed staff or ill/exposed family members. […] When SARS-CoV is present in the community surrounding a healthcare facility, preventing unrecognized SARS patients from entering the facility will be essential. Appropriate surveillance and screening measures are detailed in the surveillance section of this document and in Supplement B. Restricting access to the facility will increase the efficacy of surveillance and screening measures. […] SARS patient care requires both consumable (e.g., PPE) and durable (e.g., ventilators) supplies. Experience in other countries indicates that a SARS outbreak not only can strain a facility’s supply of these resources but also can affect the ability to order replacement supplies.
  • #91 Lessons from Severe Acute Respiratory Syndrome (SARS) | RT
    https://respiratory-therapy.com/disorders-diseases/critical-care/acute-disorders/lesson-from-sars/
    Principles of infection control and ventilator management taken from the SARS epidemic may serve during future viral outbreaks. […] Twenty-five percent of patients who are diagnosed with SARS develop acute respiratory distress syndrome and will need mechanical ventilation. […] The ventilatory management of patients with SARS does not differ much from that for patients with ARDS alone. […] A low tidal volume lung protective strategy should be adopted, with the target tidal volumes at 6 mL per ideal body weight. […] High levels of positive end-expiratory pressure (PEEP) may be used to maintain a PaO2 greater than 55 mm Hg. […] Noninvasive ventilation (NIV) has been used in early acute respiratory failure to aid in ventilation and reduce intubation rates. […] SARS patients should be nursed in private rooms with a negative pressure system in the intensive care unit.
  • #92 Lessons from Severe Acute Respiratory Syndrome (SARS) | RT
    https://respiratory-therapy.com/disorders-diseases/critical-care/acute-disorders/lesson-from-sars/
    Health care workers attending to the patients wear N95 masks, protective eye wear, full face shields, caps, long-sleeved waterproof gowns, surgical gloves, and shoe covers before entering the patients room. […] A major concern for the management of SARS patients on mechanical ventilators is the protection of health care workers from the droplet transmission of the virus. […] Heated humidification is commonly used for patients on a ventilator, but during an infectious virus outbreak, a viral-bacteria heat moisture exchanger with filter properties (HMEF) should be used for humidification purposes instead. […] The strategies presented herein have been effective in containing infection of health care workers during the SARS epidemic.
  • #93 Severe Acute Respiratory Syndrome (SARS): Lessons for Future Pandemics | Journal of Ethics | American Medical Association
    https://journalofethics.ama-assn.org/article/severe-acute-respiratory-syndrome-sars-lessons-future-pandemics/2010-09
    SARS appears to spread from person to person and through face-to-face contact, suggesting droplet spread. […] During the Hong Kong outbreak, for example, almost one-half of patients were infected in clinics, hospitals, or nursing homes, most likely through small droplets that remain suspended in the air. […] The mainstay of treatment is supportive care. […] Infection control measures, such as droplet precautions, are of particular importance. […] HCWs and visitors should wear surgical masks to prevent airborne and droplet acquisition. […] For individuals with suspected SARS, the most important element of community infection control, according to the CDC, is to remain at home for a full 10 days after fever and symptoms resolve. […] Health care institutions worldwide face a major challenge should SARS re-emerge, the risk of which is heightened by its similarities to other coronavirus strains of animal origin and the fact that it persists within animal reservoirs.
  • #94 SARS Symptoms, Causes, Treatment, Prevention, Transmission
    https://www.medicinenet.com/severe_acute_respiratory_syndrome_sars/article.htm
    Patients with SARS often require oxygen therapy, and severe cases require tracheal intubation and mechanical ventilation to support life until recovery begins. […] Severely ill patients should be admitted to the intensive-care unit. […] Medical caregivers need to follow strict policies on gloves, masks, gowns, and other protocols to avoid becoming infected. […] The SARS pandemic was brought to an end by basic public health and infection-control measures. […] Most public health officials recommend isolation for anyone diagnosed with SARS-CoV. […] The key to preventing another outbreak is to identify the first infected patients promptly before they have time to spread the illness more widely. […] If a significant outbreak of SARS occurs again, people may be advised to maintain a distance from others in the community („social distancing”) by avoiding large gatherings or close contact with others. […] However, isolation and quarantine methods have been effective in the prevention of SARS spread.