Łupież piersiowy
Patofizjologia i mechanizm

Łupież piersiowy (pityriasis capitis) to przewlekła, niezapalna dermatoza niemowlęca, manifestująca się rumieniowymi płytkami pokrytymi tłustymi, żółtawymi łuskami, pojawiająca się między 3. tygodniem a 3. miesiącem życia. Etiologia jest wieloczynnikowa, z dominującą rolą przekazywanych przez łożysko androgenów matczynych, które stymulują nadmierną aktywność gruczołów łojowych i prowadzą do hyperseborrheae. Nadprodukcja sebum powoduje przyleganie martwych korneocytów, co skutkuje charakterystycznym złuszczaniem. Istotną rolę odgrywa kolonizacja drożdżakami z rodzaju Malassezia (szczególnie M. globosa i M. restricta), które metabolizują sebum, wywołując miejscową reakcję zapalną i przyspieszone odnowienie naskórka. W badaniach ketokonazol wykazał skuteczność kliniczną u około 66% leczonych niemowląt, co potwierdza udział komponenty grzybiczej w patogenezie.

Patogeneza łupieżu piersiowego

Łupież piersiowy (łac. pityriasis capitis), znany również jako ciemieniucha, jest odmianą niemowlęcego łojotokowego zapalenia skóry. Jest to bardzo powszechna, przeważnie samoograniczająca się, przewlekła, niezapalna, złuszczająca się choroba skóry, pojawiająca się między trzecim tygodniem a pierwszymi miesiącami życia dziecka. Szczyt występowania przypada na 3. miesiąc życia.12 Zmiany skórne charakteryzują się rumieniowymi płytkami z tłustymi, żółtawymi łuskami.1

Nieznane przyczyny łupieżu piersiowego

Dokładna przyczyna łupieżu piersiowego nie jest znana.123 Badacze sądzą jednak, że jest to prawdopodobnie kombinacja kilku czynników.12 Lekarze nie zgadzają się co do jednej konkretnej przyczyny ciemieniuchy, ale dwie najczęściej wymieniane hipotezy dotyczą infekcji grzybiczej oraz nadmiernie aktywnych gruczołów łojowych.1 Należy podkreślić, że łupież piersiowy nie jest spowodowany zakażeniem bakteryjnym, alergią ani złą higieną.12

Wpływ hormonów matczynych

Jednym z głównych czynników przyczyniających się do rozwoju łupieżu piersiowego jest prawdopodobnie wpływ hormonów matczynych przekazanych dziecku przed urodzeniem.123 Przezłożyskowy transfer androgenów matczynych stymuluje wzrost gruczołów łojowych niemowlęcia.12 Te hormony mogą powodować nadmierną aktywność gruczołów łojowych, które produkują sebum – substancję oleistą.12

Nadprodukcja sebum powoduje, że martwe korneocyty (łuski) pozostają przyczepione do skóry, zamiast ulegać normalnemu złuszczaniu.12 Martwe komórki skóry, które normalnie odpadają, zaczynają przywierać do skóry z powodu nadmiaru oleju, tworząc żółte strupy i łuski na głowie.12 Ponadto zwiększona częstość występowania łojotokowego zapalenia skóry w okresie niemowlęcym i w okresie dojrzewania wspiera teorię o hormonalnym wpływie na tę chorobę.1

Rola drożdżaków Malassezia

Innym czynnikiem, który może przyczyniać się do rozwoju łupieżu piersiowego, jest Malassezia – drożdżak, który naturalnie występuje na skórze.12 Drożdżak ten rozkłada sebum, zużywając nasycone kwasy tłuszczowe i pozostawiając za sobą nienasycone kwasy tłuszczowe.1 Szczególnie szczepy M. globosa i M. restricta wykryto w ponad 80% przypadków w warunkach dermatologii ambulatoryjnej.1 Skuteczność leczenia przeciwgrzybiczego (np. ketokonazolu) dodatkowo wzmacnia ten związek przyczynowy.123

Badania wykazały, że grzyb Pityrosporum ovale (Malassezia furfur) może odgrywać rolę w powstawaniu łupieżu piersiowego. W jednym z badań grzyb był hodowany u większości pacjentów z łupieżem, ale u bardzo niewielu pacjentów z grupy kontrolnej.1 Leczenie ketokonazolem skutkowało wyleczeniem klinicznym u dwóch trzecich leczonych niemowląt.1 Jednak drożdżak ten obserwuje się również u dużej liczby zdrowych pacjentów, co sugeruje niezależną podatność na niego.12

Mechanizm powstawania łupieżu piersiowego

Mechanizm powstawania łupieżu piersiowego można opisać jako sekwencję następujących zdarzeń:

  1. Przekazanie hormonów matczynych przez łożysko pod koniec ciąży12
  2. Stymulacja i nadmierna aktywność gruczołów łojowych12
  3. Zwiększona produkcja sebum (hyperseborrhea)12
  4. Środowisko bogate w sebum sprzyja namnażaniu drożdżaków z rodzaju Malassezia12
  5. Drożdżaki, nieszkodliwe w normalnych proporcjach, stają się patogenne, gdy są obecne w dużej liczbie1
  6. Powodują specyficzną reakcję zapalną, która objawia się zaczerwienieniem i przyspieszonym odnowieniem komórek skóry głowy12
  7. Prowadzi to do nietypowego złuszczania (odpadania martwej skóry) i tworzenia się łusek (pozostałości martwej skóry) na powierzchni skóry1

Inne czynniki wpływające na rozwój łupieżu piersiowego

Badania wykazały, że niemowlęta z łupieżem piersiowym często mają członka rodziny z atopowym zapaleniem skóry i/lub astmą.12 To może sugerować podłoże genetyczne lub wspólne mechanizmy immunologiczne.1

Dodatkowe czynniki, które mogą przyczynić się do rozwoju łupieżu piersiowego, obejmują:

  • Zaburzenia równowagi bakteryjnej w jelitach powodujące infekcje drożdżakowe lub grzybicze12
  • Dysbakterioza jelitowa i potencjalnie SIBO (przerost bakterii w jelicie cienkim)1
  • Stosowanie antybiotyków, które mogą zwiększać ryzyko infekcji drożdżakowych12
  • Problemy z barierą ochronną skóry1
  • Nadreaktywna odpowiedź immunologiczna12
  • Zaburzenie równowagi naturalnych bakterii i drożdżaków skóry12

Przebieg i rokowanie

Łupież piersiowy ma zwykle łagodny i samoograniczający się przebieg.12 Większość niemowląt nie odczuwa żadnych skutków ubocznych, a karmienie i sen nie są zaburzone.1 Choroba zwykle ustępuje bez interwencji w ciągu kilku tygodni do kilku miesięcy.12

Jeśli łupież piersiowy utrzymuje się po 12 miesiącach życia, należy rozważyć alternatywne rozpoznanie i przeprowadzić dalsze badania.12 Leczenie jest zwykle skuteczne w łagodzeniu objawów, chociaż problem może powrócić w pierwszym roku życia dziecka, nawet przy odpowiednim leczeniu.12

U niektórych niemowląt, które miały łupież piersiowy, mogą rozwinąć się inne rodzaje łojotokowego zapalenia skóry, takie jak łupież, w starszym wieku.1

Podsumowanie patogenezy łupieżu piersiowego

Chociaż dokładna przyczyna łupieżu piersiowego pozostaje nieznana, aktualna wiedza wskazuje na złożoną interakcję między hormonami matczynymi, aktywnością gruczołów łojowych oraz kolonizacją i namnażaniem drożdżaków Malassezia na skórze głowy niemowlęcia. Ta interakcja prowadzi do zwiększonej produkcji sebum, nieprawidłowego złuszczania się komórek naskórka i rozwoju charakterystycznych tłustych, żółtawych łusek.123

Stany zapalne skóry związane z łupieżem piersiowym nie są spowodowane zakażeniami bakteryjnymi, alergiami ani złą higieną, ale raczej fizjologiczną odpowiedzią na kombinację wyżej wymienionych czynników. Na szczęście, łupież piersiowy zwykle ustępuje samoistnie i rzadko wymaga intensywnej interwencji medycznej.123

Kolejne rozdziały

Zapraszamy do dalszego czytania naszego leksykonu.

Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.

  1. 10.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Cradle Cap – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK531463/
    Cradle cap, or pityriasis capitis, is a subset of infantile seborrheic dermatitis (ISD). It is a very common, mostly self-limiting, chronic non-inflammatory scaling skin condition that presents between the third week and first couple months of life. The peak incidence is at 3 months of life. The skin manifestations are marked by erythematous plaques with greasy-appearing yellowish scale. Cradle cap’s name is analogous to its anatomical location. It can be found in areas dense in sebaceous gland activity, such as the scalp, T line of the face and external ears. […] Currently, there is no known cause for cradle cap. However, there are many factors that have been hypothesized to influence the condition. One hypothesis is the secondary influence of maternal circulating hormones resulting in overactive sebaceous gland activity. Sebaceous glands produce sebum, which is an oil-like substance. Overproduction of sebum causes the dead corneocytes (scale) to remain adherent instead of undergoing normal desquamation. Furthermore, the increase in frequency of seborrheic dermatitis during infancy and adolescence supports a hormonal influence on the condition. Malassezia, a yeast, has been implicated in many cases of cradle cap. The yeast breaks down sebum, consuming the saturated fatty acids, and subsequently leaves the unsaturated fatty acids behind. M. globosa and M. restricta have been found in over 80% of all age cases in an outpatient dermatology setting. The response from anti-fungals further strengthens this causal relationship. However, the yeast is also seen in a large quantity of normal patients, suggesting an independent susceptibility to the yeast.
  • #1 Cradle Cap (Seborrheic Dermatitis) in Infants – Kidshealth | Akron Children’s
    https://www.akronchildrens.org/kidshealth/en/parents/cradle-cap.html
    Cradle cap is the common term for seborrheic dermatitis of the scalp in infants. […] The exact cause of cradle cap isn’t known. It’s likely due to a combination of things. Too much skin oil (sebum) in the oil glands and hair follicles and a type of yeast found on the skin called Malassezia may play roles in the development of seborrheic dermatitis.
  • #1 Cradle cap – Wikipedia
    https://en.wikipedia.org/wiki/Cradle_cap
    Cradle cap is not caused by bacterial infection, allergy or poor hygiene. […] Doctors do not agree on what causes cradle cap, but the two most common hypotheses are fungal infection and overactive sebaceous glands. Cradle cap is an inflammatory condition. […] Possibly it has to do with overactive sebaceous glands in the skin of newborn babies, due to the mother’s hormones still in the baby’s circulation. The glands release a greasy substance that makes old skin cells attach to the scalp instead of falling off as they dry. There is a relationship with skin yeasts (Malassezia furfur).
  • #1 Cradle cap – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/cradle-cap/symptoms-causes/syc-20350396
    Cradle cap causes crusty or oily scaly patches on a baby’s scalp. The condition isn’t painful or itchy. But it can cause thick white or yellow scales that aren’t easy to remove. […] The cause of cradle cap isn’t known. One factor may be hormones that pass from the mother to the baby before birth. These hormones can cause oil glands and hair follicles to make too much oil. This oil is called sebum. […] Another factor may be a fungus called malassezia (mal-uh-SEE-zhuh) that grows in the sebum along with bacteria. Antifungal treatments often help control symptoms. This supports the idea that malassezia is a cause. An example of an antifungal treatment is ketoconazole. […] Cradle cap isn’t contagious, and it’s not caused by poor hygiene.
  • #1 Cradle cap and seborrheic dermatitis in infants – UpToDate
    https://www.uptodate.com/contents/cradle-cap-and-seborrheic-dermatitis-in-infants
    The pathogenesis of infantile seborrheic dermatitis is not known. Transplacental transfer of maternal androgens stimulates the growth of the infant’s sebaceous glands, which are necessary but not sufficient for the development of seborrheic dermatitis. The role of Malassezia, a lipid-dependent yeast, is not clear. Malassezia colonization has been reported in infants with seborrheic dermatitis, infants with other dermatologic conditions, and in normal infants.
  • #1 Cradle Cap
    https://www.seattlechildrens.org/conditions/a-z/cradle-cap/
    Cradle cap is probably caused by hormones from the mother. These hormones cross the placenta before birth. The hormones cause the oil glands in the skin to become overactive. They then release more oil than normal. […] Dead skin cells normally fall off. The extra oil causes these cells to „stick” to the skin. These cells form yellow crusts and scales on the scalp. […] It’s caused by overactive oil glands in the scalp.
  • #1 Seborrheic Dermatitis (Cradle Cap) | Rady Children’s Hospital
    https://www.rchsd.org/programs-services/dermatology/eczema-and-inflammatory-skin-disease-center/other-inflammatory-diseases/seborrheic-dermatitis-cradle-cap/
    Seborrheic dermatitis is a chronic inflammatory disorder most commonly seen in infants and adolescents. […] The etiology of seborrheic dermatitis is unknown, although a few studies have indicated that the fungal organism Pityrosporum ovale (Malassezia furfur) plays a role. […] In these studies, the fungus was cultured in the majority of the seborrhea patients, but in very few control patients. […] In one study, treatment with ketoconazole resulted clinical cure in two-thirds of infants treated. […] However, these studies are controversial since M. furfur in other studies has been found to be part of the normal flora in healthy individuals.
  • #1 The causes of cradle cap | Ducray
    https://www.ducray.com/en/cradle-cap/causes
    The exact origin of cradle cap is still unknown to this day. […] Even if we do not know the reasons for its appearance in young children, the mechanisms responsible for the appearance of cradle cap are well identified. […] Among the causes of cradle cap onset, excess sebum is the first. […] In the case of cradle cap, sebum is secreted in excess, so there is hyper-seborrhea on the surface of the skin. This excess of sebum is partly due to the mother’s hormones transmitted at the end of pregnancy. […] An environment rich in sebum promotes the proliferation of yeasts of the Malassezia genus. […] These yeasts, harmless in normal proportions, become pathogenic when they are present in large numbers. They cause a specific inflammatory reaction that results in redness and accelerated renewal of scalp and skin cells, leading to unusual desquamation (dead skin falling off) and scales (dead skin residue) forming on the skin surface.
  • #1 Cradle Cap – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/sites/books/NBK531463/
    Cradle cap classically presents as greasy, non-inflammatory plaques with overlying yellowish scale, on the vertex and frontal regions of the scalp. Cradle cap is usually asymptomatic; neither painful nor pruritic. Most infants generally have no side effects from the condition with feeding and sleep not being interrupted. Studies have shown that infants with cradle cap commonly have a family member with either atopic dermatitis and/or asthma.
  • #1 How to Treat Cradle Cap | UPMC HealthBeat
    https://share.upmc.com/2024/09/how-to-treat-cradle-cap/
    Cradle cap (medical name: seborrheic dermatitis) is a rash that usually occurs on the top of a babys head. […] Doctors arent exactly sure what causes cradle cap, but its not the result of poor hygiene, allergies, or an infection. […] Possible causes include: Heredity Babies with cradle cap may have relatives with eczema or asthma. Hormones from the mothers body These may remain in the babys body after birth. These hormones may cause oil glands to produce too much sebum (skin oil). The dead skin cells stick together in the sebum instead of sloughing off. Malassezia a yeast that most people have on their skin. When the yeast combines with too much sebum, it forms cradle cap.
  • #1 Cradle Cap Main Info Page – Documenting Hope
    https://documentinghope.com/cradle-cap/
    Cradle cap, “infantile seborrheic dermatitis”, is a collection of odd patches of a thick, yellowish, oily, greasy, scaly, dry, crusty skin condition that can soon develop on your baby’s scalp shortly after birth, for seemingly no reason at all. […] The American Academy of Pediatrics does not have a medical theory for cradle cap, nor do they have many causation factors. […] Your doctor may feel that there is a bacterial infection in the sebaceous glands caused by a fungus such as yeast triggering the infantile seborrheic dermatitis. […] Inflammation of the sebaceous glands can be caused by maternal hormones from the birthing process transferring to the baby in the womb, causing an increase production of sebum oil which eventually results in a blockage trapping flaky skin. […] Infantile seborrheic dermatitis is known to have an underlying bacterial imbalance in the gut causing yeast or fungal infections.
  • #1 Cradle Cap Main Info Page – Documenting Hope
    https://documentinghope.com/cradle-cap/
    Therefore, when underlying toxins increase due to gut dysbiosis, leaky gut and possibly SIBO (Small Intestinal Bacterial Overgrowth), they lay the groundwork for possible yeast and fungus infections in the body that the body will naturally try and eliminate or detox first through the skin. […] Yeast infections in cradle cap are typically from the Malassenzia (Pityrosporum) strain of yeast; both cradle cap and dandruff have been found to be caused by this specific strain of yeast. […] Antibiotics also contribute to cradle cap because they increase yeast infections which are known to trigger cradle cap. […] Ultimately this lowers the baby’s immune system and increases the likelihood of yeast, fungus and other pathogens in the baby’s digestive tract.
  • #1 Cradle Cap in Babies: Symptoms, Causes, and Natural Home Remedies
    https://www.tinyhealth.com/blog/cradle-cap-symptoms-causes-remedies
    Cradle cap, or infantile seborrheic dermatitis, is a common condition that affects about 10% of babies under a month old, then peaks around three months, affecting up to 70% of infants. […] The exact cause of cradle cap isn’t fully understood, but several factors may contribute. Your baby’s oil glands may produce too much oil (sebum), which can cause skin cells to stick to their scalp instead of shedding naturally. This extra oil may result from hormones passed from mom to baby, or other factors like dry air, temperature changes, or harsh skincare products that strip natural oils from the skin. […] Other causes may include issues with the skin’s protective barrier, changes in the amount or type of natural skin oils, an overactive immune response, and an imbalance in the skin’s natural bacteria and yeast.
  • #1 Cradle Cap – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK531463/
    Cradle cap classically presents as greasy, non-inflammatory plaques with overlying yellowish scale, on the vertex and frontal regions of the scalp. Cradle cap is usually asymptomatic; neither painful nor pruritic. Most infants generally have no side effects from the condition with feeding and sleep not being interrupted. […] Cradle cap is generally a self-limiting skin condition. Prevention of cradle cap is difficult, secondary to the unknown cause of the condition, yet many believe hormones play a strong role. Moreover, the treatment for mild and localized cradle cap should remain conservative. The infant should be washed daily with a gentle baby shampoo along with an emollient (white petrolatum, mineral oil, baby oil) prior to the shampoo use. The emollient may prove more effective if remaining in contact with the skin for a prolonged period of time, overnight if necessary, to break up the scale. Afterward, there should be the gentle removal of scale with a soft toothbrush or cradle cap comb. The oil will help soften the scale making it easier for removal. Once the scale is removed, parents should continue daily shampooing of their infant’s affected areas to prevent recurrence. Cradle cap that does not improve after conservative measures or that is extensive in nature can be treated with an antifungal cream such as ketoconazole 2% or a topical steroid cream such as hydrocortisone 1% for approximately 1-2 weeks. […] Cradle cap is generally self-limiting and benign. Yet, if the condition persists after 12 months of age, alternative diagnoses should be further investigated.
  • #1 Cradle cap (infantile seborrhoeic dermatitis)
    https://dermnetnz.org/topics/cradle-cap
    Cradle cap, or pityriasis capitis, is infantile seborrhoeic dermatitis affecting the scalp. […] The cause of cradle cap is not known. It may be related to hyperactivity of sebaceous glands responsive to residual circulating maternal androgens. Malassezia has also been implicated although its exact role is not clear. […] Cradle cap is benign and self-limiting. It usually resolves without intervention over the course of weeks to several months. If disease persists beyond 12 months, the diagnosis should be reconsidered.
  • #1 Cradle Cap
    https://www.massgeneral.org/condition/cradle-cap-seborrheic-dermatitis
    Researchers don’t know the exact cause of this skin condition. It is not contagious. It is not an infection or allergy. It is not caused by poor hygiene. […] Cradle cap is usually diagnosed based on a physical exam of your child. The rash involved with cradle cap is unique. It can usually be diagnosed by a physical exam. […] Treatment will depend on your child’s symptoms, age, and general health. It will also depend on how severe the condition is. […] The problem will go away on its own over time. But most parents prefer treatment because it usually helps reduce or get rid of the problem. Treatment may also decrease your level of anxiety as a parent. Even with treatment, the problem may come back during the baby’s first year of life. Treatment is usually effective in helping symptoms.
  • #1 Cradle cap | healthdirect
    https://www.healthdirect.gov.au/cradle-cap
    Cradle cap is thought to be caused by too much oil production by the skin. […] The cause of cradle cap is not clear. There are a few possible causes. […] These hormones can cause your babys sebaceous glands to produce too much sebum. The excess sebum causes old skin cells to stick to the scalp, instead of drying up and falling off as they would normally do. […] Cradle cap is not contagious and is not caused by poor hygiene. […] Research has found that babies who get cradle cap often have family members with allergy-type conditions, such as asthma and eczema. […] Some babies who have cradle cap may develop other types of seborrhoeic dermatitis, such as dandruff, when they are older.
  • #2 Cradle Cap – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/sites/books/NBK531463/
    Cradle cap, or pityriasis capitis, is a subset of infantile seborrheic dermatitis (ISD). It is a very common, mostly self-limiting, chronic non-inflammatory scaling skin condition that presents between the third week and first couple months of life. The peak incidence is at 3 months of life. The skin manifestations are marked by erythematous plaques with greasy-appearing yellowish scale. Cradle cap’s name is analogous to its anatomical location. It can be found in areas dense in sebaceous gland activity, such as the scalp, T line of the face and external ears. […] Currently, there is no known cause for cradle cap. However, there are many factors that have been hypothesized to influence the condition. One hypothesis is the secondary influence of maternal circulating hormones resulting in overactive sebaceous gland activity. Sebaceous glands produce sebum, which is an oil-like substance. Overproduction of sebum causes the dead corneocytes (scale) to remain adherent instead of undergoing normal desquamation. Furthermore, the increase in frequency of seborrheic dermatitis during infancy and adolescence supports a hormonal influence on the condition. Malassezia, a yeast, has been implicated in many cases of cradle cap. The yeast breaks down sebum, consuming the saturated fatty acids, and subsequently leaves the unsaturated fatty acids behind. M. globosa and M. restricta have been found in over 80% of all age cases in an outpatient dermatology setting. The response from anti-fungals further strengthens this causal relationship. However, the yeast is also seen in a large quantity of normal patients, suggesting an independent susceptibility to the yeast.
  • #2 Cradle cap and seborrheic dermatitis in infants – UpToDate
    https://www.uptodate.com/contents/cradle-cap-and-seborrheic-dermatitis-in-infants
    The pathogenesis of infantile seborrheic dermatitis is not known. Transplacental transfer of maternal androgens stimulates the growth of the infant’s sebaceous glands, which are necessary but not sufficient for the development of seborrheic dermatitis. The role of Malassezia, a lipid-dependent yeast, is not clear. Malassezia colonization has been reported in infants with seborrheic dermatitis, infants with other dermatologic conditions, and in normal infants.
  • #2 Cradle Cap (Seborrheic Dermatitis in Infants) Causes
    https://my.clevelandclinic.org/health/diseases/15786-cradle-cap-seborrheic-dermatitis-in-infants
    Researchers dont fully understand why babies get cradle cap. However, they believe its likely due to a combination of factors. […] For example, glands in your babys scalp may produce too much oil (possibly due to hormones they receive from their mother). This causes skin cells that normally shed from your babys scalp to stay stuck to their scalp instead. A certain yeast (Malassezia) that naturally lives on your babys skin may also play a role, but researchers arent sure exactly how.
  • #2 Cradle cap – Wikipedia
    https://en.wikipedia.org/wiki/Cradle_cap
    Cradle cap is not caused by bacterial infection, allergy or poor hygiene. […] Doctors do not agree on what causes cradle cap, but the two most common hypotheses are fungal infection and overactive sebaceous glands. Cradle cap is an inflammatory condition. […] Possibly it has to do with overactive sebaceous glands in the skin of newborn babies, due to the mother’s hormones still in the baby’s circulation. The glands release a greasy substance that makes old skin cells attach to the scalp instead of falling off as they dry. There is a relationship with skin yeasts (Malassezia furfur).
  • #2 Cradle cap – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/cradle-cap/symptoms-causes/syc-20350396
    Cradle cap causes crusty or oily scaly patches on a baby’s scalp. The condition isn’t painful or itchy. But it can cause thick white or yellow scales that aren’t easy to remove. […] The cause of cradle cap isn’t known. One factor may be hormones that pass from the mother to the baby before birth. These hormones can cause oil glands and hair follicles to make too much oil. This oil is called sebum. […] Another factor may be a fungus called malassezia (mal-uh-SEE-zhuh) that grows in the sebum along with bacteria. Antifungal treatments often help control symptoms. This supports the idea that malassezia is a cause. An example of an antifungal treatment is ketoconazole. […] Cradle cap isn’t contagious, and it’s not caused by poor hygiene.
  • #2 Cradle cap and seborrheic dermatitis in infants – UpToDate
    https://www.uptodate.com/contents/cradle-cap-and-seborrheic-dermatitis-in-infants/print
    Seborrheic dermatitis occurs in infants between the ages of 3 weeks and 12 months. […] The pathogenesis of infantile seborrheic dermatitis is not known. Transplacental transfer of maternal androgens stimulates the growth of the infant’s sebaceous glands, which are necessary but not sufficient for the development of seborrheic dermatitis. The role of Malassezia, a lipid-dependent yeast, is not clear. Malassezia colonization has been reported in infants with seborrheic dermatitis, infants with other dermatologic conditions, and in normal infants.
  • #2 Cradle Cap – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK531463/
    Cradle cap, or pityriasis capitis, is a subset of infantile seborrheic dermatitis (ISD). It is a very common, mostly self-limiting, chronic non-inflammatory scaling skin condition that presents between the third week and first couple months of life. The peak incidence is at 3 months of life. The skin manifestations are marked by erythematous plaques with greasy-appearing yellowish scale. Cradle cap’s name is analogous to its anatomical location. It can be found in areas dense in sebaceous gland activity, such as the scalp, T line of the face and external ears. […] Currently, there is no known cause for cradle cap. However, there are many factors that have been hypothesized to influence the condition. One hypothesis is the secondary influence of maternal circulating hormones resulting in overactive sebaceous gland activity. Sebaceous glands produce sebum, which is an oil-like substance. Overproduction of sebum causes the dead corneocytes (scale) to remain adherent instead of undergoing normal desquamation. Furthermore, the increase in frequency of seborrheic dermatitis during infancy and adolescence supports a hormonal influence on the condition. Malassezia, a yeast, has been implicated in many cases of cradle cap. The yeast breaks down sebum, consuming the saturated fatty acids, and subsequently leaves the unsaturated fatty acids behind. M. globosa and M. restricta have been found in over 80% of all age cases in an outpatient dermatology setting. The response from anti-fungals further strengthens this causal relationship. However, the yeast is also seen in a large quantity of normal patients, suggesting an independent susceptibility to the yeast.
  • #2 Cradle cap: Treatment, causes, and prevention
    https://www.medicalnewstoday.com/articles/218942
    Cradle cap is a greasy, yellowish, scaly rash that appears in patches on the scalps of infants. It is not clear what causes cradle cap, but it may stem from overactive sebaceous glands, a fungal infection, or both. […] It is not clear what causes cradle cap, but it is not caused by allergy, bacterial infection, or bad hygiene. It may stem from overactive sebaceous glands, a fungal infection, or both. The sebaceous glands are found in the skin and produce an oil-like substance, known as sebum. Overactive sebaceous glands may produce too much sebum, and this could prevent the old skin cells from drying and falling off the scalp. Instead, they stick to the scalp. […] The reason why the glands are overactive may be because the mothers hormones stay in the babys body for a number of months after birth. If a fungal infection occurs, it could be the result of the mother taking antibiotics before giving birth, or because the baby was given them up to a week after birth. Antibiotics destroy bacteria that cause damage, but they can also destroy the useful bacteria that prevent things like fungal infection.
  • #2 Cradle cap | Better Health Channel
    https://www.betterhealth.vic.gov.au/health/healthyliving/cradle-cap
    Cradle cap is an inflammatory skin condition that affects babies. It causes yellow crusts on the scalp. It is a form of seborrhoeic dermatitis. […] Sebaceous glands in the scalp make sebum, which oils the skin. It is thought that babies have high levels of maternal hormones in their bodies for several weeks or months following birth and these hormones enlarge the glands, making more sebum. Some component in the sebum, as yet unknown, causes skin inflammation. […] The cradle cap can come back, even when treated properly, because the glands continue to produce sebum for several months after birth.
  • #2 Cradle cap (infantile seborrhoeic dermatitis)
    https://dermnetnz.org/topics/cradle-cap
    Cradle cap, or pityriasis capitis, is infantile seborrhoeic dermatitis affecting the scalp. […] The cause of cradle cap is not known. It may be related to hyperactivity of sebaceous glands responsive to residual circulating maternal androgens. Malassezia has also been implicated although its exact role is not clear. […] Cradle cap is benign and self-limiting. It usually resolves without intervention over the course of weeks to several months. If disease persists beyond 12 months, the diagnosis should be reconsidered.
  • #2 Azthena logo with the word Azthena
    https://www.news-medical.net/health/Cradle-Cap-Diagnosis-and-Treatment.aspx
    Cradle cap is caused by inflammation of the skin due to the excessive sebum secretion. The hypersecretion of sebum may be a response to the high levels of hormones (found in the baby’s blood) that stimulate its production and release. […] The sebum is a fatty product released by the sebaceous follicles in the dermis.
  • #2 Cradle Cap in Babies: Symptoms, Causes, and Natural Home Remedies
    https://www.tinyhealth.com/blog/cradle-cap-symptoms-causes-remedies
    When this natural balance is disrupted, it can lead to overgrowth of certain microbes like Malassezia (a common yeast) and Staphylococcus aureus (a type of bacteria). This may trigger inflammation and weaken the skin’s protective barrier. Research has found these microbes are more common in areas of cradle cap compared to healthy skin in babies. […] Specific strains like Malassezia restricta and M. globosa break down skin oils to release fatty acid byproducts. These byproducts can irritate the skin, causing inflammation and flaking, which may lead to cradle cap.
  • #2 Seborrheic Dermatitis: Symptoms, Complications, and More
    https://www.verywellhealth.com/cradle-cap-5185790
    The causes of seborrheic dermatitis are unknown, but it’s believed that one of the factors is an inflammatory response to Malassezia yeast on the skin. […] The following may contribute to the condition: Overgrowth of Malassezia yeast: This yeast is part of the group of organisms that normally live on the skin. It typically doesn’t cause any trouble, but can when there is too much of it. […] An inflammatory reaction that may happen in response to an excess of yeast, increased androgens, and/or increased skin lipids. […] The causes of seborrheic dermatitis are unclear, but researchers believe that it is likely due to several factors. […] Possible causes are an overgrowth of yeast and an inflammatory reaction to it or to increased skin lipids or hormone levels.
  • #2 Cradle cap | healthdirect
    https://www.healthdirect.gov.au/cradle-cap
    Cradle cap is thought to be caused by too much oil production by the skin. […] The cause of cradle cap is not clear. There are a few possible causes. […] These hormones can cause your babys sebaceous glands to produce too much sebum. The excess sebum causes old skin cells to stick to the scalp, instead of drying up and falling off as they would normally do. […] Cradle cap is not contagious and is not caused by poor hygiene. […] Research has found that babies who get cradle cap often have family members with allergy-type conditions, such as asthma and eczema. […] Some babies who have cradle cap may develop other types of seborrhoeic dermatitis, such as dandruff, when they are older.
  • #2 Cradle Cap Main Info Page – Documenting Hope
    https://documentinghope.com/cradle-cap/
    Therefore, when underlying toxins increase due to gut dysbiosis, leaky gut and possibly SIBO (Small Intestinal Bacterial Overgrowth), they lay the groundwork for possible yeast and fungus infections in the body that the body will naturally try and eliminate or detox first through the skin. […] Yeast infections in cradle cap are typically from the Malassenzia (Pityrosporum) strain of yeast; both cradle cap and dandruff have been found to be caused by this specific strain of yeast. […] Antibiotics also contribute to cradle cap because they increase yeast infections which are known to trigger cradle cap. […] Ultimately this lowers the baby’s immune system and increases the likelihood of yeast, fungus and other pathogens in the baby’s digestive tract.
  • #2 Seborrheic Dermatitis: Causes, Symptoms, Treatment | National Eczema Association
    https://nationaleczema.org/types-of-eczema/seborrheic-dermatitis/
    The trigger for seborrheic dermatitis is usually an inflammatory reaction to excess Malassezia yeast, also sometimes called pityrosporum, on the skin. This yeast, an organism that normally lives on the skins surface, is the likely cause of seborrheic dermatitis. The Malessezia overgrows and the immune system seems to overreact to it, leading to a fungal infection that results in skin changes. […] Seborrheic dermatitis is not an allergy. It is caused by genetic and environmental factors.
  • #2 How to manage cradle cap naturally – NatureDoc
    https://naturedoc.com/how-to-manage-cradle-cap-naturally/
    Cradle cap, also known as scalp Seborrheic Dermatitis, is an inflammatory scaley skin condition which usually occurs between the ages of 2 weeks and 12 months in babies. […] Although the exact cause of cradle cap in babies remains unknown, many cases boil down to hormones from the placenta passed from the mother to the baby before birth, causing an over production of oil (sebum) in the oil glands as well as the hair follicles. […] Cradle cap can also be fungal in nature, and this skin condition is thought to flare up and proliferate due to an overreaction to a yeast called Malassezia on the scalp. […] If it is not clearing when using the targeted topical approach, then this might reflect a more systemic yeast infection or gut dysbiosis (underlying imbalance in gut flora and microbiome).
  • #2 How to Get Rid of Cradle Cap: Home Remedies and When to Seek Help
    https://www.healthline.com/health/parenting/how-to-get-rid-of-cradle-cap
    Cradle cap, or crib cap, is a type of seborrheic dermatitis your baby can develop. […] Cradle cap, sometimes also called crib cap, is the baby version of seborrheic dermatitis. Seborrheic dermatitis causes dandruff in adults. In babies, it causes extremely thick and flaky skin on a babys scalp. […] Cradle cap is very common, but little is known about what exactly causes it. This is one reason it may be hard to remove or prevent. In adults, there appears to be a link between seborrheic dermatitis and the Malassezia species of yeast, but the association is less clear in infants. […] Some scientists believe theres a hormonal link since it appears at birth, goes away, and then often returns around puberty. […] Cradle cap is mostly harmless and usually clears up on its own. Often it goes away by babys first birthday, though in some children it may not clear up until they are between 2 and 4 years old.
  • #2 Cradle Cap
    https://library.southcoast.org/Conditions/Heart/Tools/90,P01893
    Cradle cap (infant seborrheic dermatitis) is scaly patches on a baby’s scalp. […] Researchers don’t know the exact cause of this skin condition. It is not contagious. It is not an infection or allergy. It is not caused by poor hygiene. […] Babies between the ages of 3 weeks and 12 months are at greater risk of getting cradle cap. […] Symptoms can occur a bit differently in each child. They can include dry or greasy yellowish scales on the scalp. The scalp may also appear red. It usually does not itch or cause the baby discomfort. […] Cradle cap is usually diagnosed based on a physical exam of your child. The rash involved with cradle cap is unique. It can usually be diagnosed by a physical exam. […] Treatment will depend on your child’s symptoms, age, and general health. It will also depend on how severe the condition is.
  • #2 The causes of cradle cap | Ducray
    https://www.ducray.com/en/cradle-cap/causes
    The exact origin of cradle cap is still unknown to this day. […] Even if we do not know the reasons for its appearance in young children, the mechanisms responsible for the appearance of cradle cap are well identified. […] Among the causes of cradle cap onset, excess sebum is the first. […] In the case of cradle cap, sebum is secreted in excess, so there is hyper-seborrhea on the surface of the skin. This excess of sebum is partly due to the mother’s hormones transmitted at the end of pregnancy. […] An environment rich in sebum promotes the proliferation of yeasts of the Malassezia genus. […] These yeasts, harmless in normal proportions, become pathogenic when they are present in large numbers. They cause a specific inflammatory reaction that results in redness and accelerated renewal of scalp and skin cells, leading to unusual desquamation (dead skin falling off) and scales (dead skin residue) forming on the skin surface.
  • #2 Cradle Cap
    https://www.massgeneral.org/condition/cradle-cap-seborrheic-dermatitis
    Researchers don’t know the exact cause of this skin condition. It is not contagious. It is not an infection or allergy. It is not caused by poor hygiene. […] Cradle cap is usually diagnosed based on a physical exam of your child. The rash involved with cradle cap is unique. It can usually be diagnosed by a physical exam. […] Treatment will depend on your child’s symptoms, age, and general health. It will also depend on how severe the condition is. […] The problem will go away on its own over time. But most parents prefer treatment because it usually helps reduce or get rid of the problem. Treatment may also decrease your level of anxiety as a parent. Even with treatment, the problem may come back during the baby’s first year of life. Treatment is usually effective in helping symptoms.
  • #3 Cradle Cap (Seborrheic Dermatitis in Infants) Causes
    https://my.clevelandclinic.org/health/diseases/15786-cradle-cap-seborrheic-dermatitis-in-infants
    Researchers dont fully understand why babies get cradle cap. However, they believe its likely due to a combination of factors. […] For example, glands in your babys scalp may produce too much oil (possibly due to hormones they receive from their mother). This causes skin cells that normally shed from your babys scalp to stay stuck to their scalp instead. A certain yeast (Malassezia) that naturally lives on your babys skin may also play a role, but researchers arent sure exactly how.
  • #3 Cradle Cap
    https://www.seattlechildrens.org/conditions/a-z/cradle-cap/
    Cradle cap is probably caused by hormones from the mother. These hormones cross the placenta before birth. The hormones cause the oil glands in the skin to become overactive. They then release more oil than normal. […] Dead skin cells normally fall off. The extra oil causes these cells to „stick” to the skin. These cells form yellow crusts and scales on the scalp. […] It’s caused by overactive oil glands in the scalp.
  • #3 Seborrheic Dermatitis (Cradle Cap) | Rady Children’s Hospital
    https://www.rchsd.org/programs-services/dermatology/eczema-and-inflammatory-skin-disease-center/other-inflammatory-diseases/seborrheic-dermatitis-cradle-cap/
    Seborrheic dermatitis is a chronic inflammatory disorder most commonly seen in infants and adolescents. […] The etiology of seborrheic dermatitis is unknown, although a few studies have indicated that the fungal organism Pityrosporum ovale (Malassezia furfur) plays a role. […] In these studies, the fungus was cultured in the majority of the seborrhea patients, but in very few control patients. […] In one study, treatment with ketoconazole resulted clinical cure in two-thirds of infants treated. […] However, these studies are controversial since M. furfur in other studies has been found to be part of the normal flora in healthy individuals.
  • #3 Seborrheic Dermatitis: Symptoms, Complications, and More
    https://www.verywellhealth.com/cradle-cap-5185790
    The causes of seborrheic dermatitis are unknown, but it’s believed that one of the factors is an inflammatory response to Malassezia yeast on the skin. […] The following may contribute to the condition: Overgrowth of Malassezia yeast: This yeast is part of the group of organisms that normally live on the skin. It typically doesn’t cause any trouble, but can when there is too much of it. […] An inflammatory reaction that may happen in response to an excess of yeast, increased androgens, and/or increased skin lipids. […] The causes of seborrheic dermatitis are unclear, but researchers believe that it is likely due to several factors. […] Possible causes are an overgrowth of yeast and an inflammatory reaction to it or to increased skin lipids or hormone levels.
  • #3 Cradle cap (infantile seborrhoeic dermatitis)
    https://dermnetnz.org/topics/cradle-cap
    Cradle cap, or pityriasis capitis, is infantile seborrhoeic dermatitis affecting the scalp. […] The cause of cradle cap is not known. It may be related to hyperactivity of sebaceous glands responsive to residual circulating maternal androgens. Malassezia has also been implicated although its exact role is not clear. […] Cradle cap is benign and self-limiting. It usually resolves without intervention over the course of weeks to several months. If disease persists beyond 12 months, the diagnosis should be reconsidered.