Materiały źródłowe

• #1 Keratosis Pilaris – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK546708/

  Keratosis pilaris is a common dermatologic condition. The most common patient population is adolescents, with 50 to 80 percent affected. The disorder is also frequently seen in adults, with 40 percent of the adult population affected. However, because keratosis pilaris is an underreported condition, the prevalence of the condition may be higher. Race and sex do not predispose patients to develop keratosis pilaris. […] Keratosis pilaris is a chronic condition most common in the adolescent population. […] Keratosis pilaris is among the most common dermatologic conditions and can be considered a normal variant.

• #2 Keratosis Pilaris: Practice Essentials, Pathophysiology, Etiology of Keratosis Pilaris

  https://emedicine.medscape.com/article/1070651-overview

  Keratosis pilaris (KP) is overall a very common condition and is present worldwide. […] Keratosis pilaris (KP) has no widely described racial predilection or predominance. It is commonly noted worldwide in persons of all races. […] Both sexes are affected by keratosis pilaris (KP), but females may be affected more frequently than males. […] Age of onset of keratosis pilaris (KP) is often within the first decade of life; symptoms particularly intensify during puberty. However, keratosis pilaris may manifest in persons of any age and is common in young children. Some authorities believe individuals can outgrow the disorder by early adulthood, but often this is not the case.

• #3 A Review of the Scoring and Assessment of Keratosis Pilaris

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10410087/

  KP is found in 50% of children and 40% of adults. As KP is an underreported condition, the actual prevalence may be much higher. It has no known gender or racial predilection and is reported to begin in childhood. In a survey of 49 British patients aged 240 years, incidence was highest in the first decade of life and decreased with age. Notably, this 1994 survey was only conducted in the UK, and further recent studies would need to validate this. Conversely, many report that KP may manifest in an individual at any age and that cases can persist throughout adulthood. Some patients in the study also reported an improvement in the summer and worsening KP in the winter when the conditions are drier. […] From a research and epidemiological perspective, there is limited documentation on the incidence, patterns, exacerbations, and seasonal trends of KP.

• #4 Keratosis Pilaris: Symptoms, Causes, and Treatment — DermNet

  https://dermnetnz.org/topics/keratosis-pilaris

  Keratosis pilaris is typically seen in children and young adults. It affects 50-70% of teenagers and 40% of adults. […] There is no cure for keratosis pilaris, however, it often clears up during adult life.

• #5 Keratosis Pilaris: A Rough and Bumpy Review

  https://practicaldermatology.com/columns/clinical-focus-1/keratosis-pilaris-a-rough-and-bumpy-review/23618/

  Keratosis pilaris (KP) is a common skin disorder characterized by rough follicular papules, giving it the unfortunate nickname chicken skin. It is most often seen in children and adolescents and is estimated to affect between 50 and 80 percent of all adolescents. […] Despite its benign nature, KP can be a frustrating disorder for the patient, families, and clinicians, due to the cosmetic impact and lack of a clear solution. […] KP also has a strong link with atopy, ichthyosis vulgaris and xerosis. Thus, oral supplements that have been shown to improve atopic dermatitis and skin dryness could be useful for KP. […] KP is an extremely common, benign skin disorder that can be quite distressing for the patient due to its appearance on visible areas of the body, dryness, and rough texture. Although there is no clear consensus on the solution for KP, many different treatments are available to reduce its symptoms.

• #6 Keratosis pilaris – Wikipedia

  https://en.wikipedia.org/wiki/Keratosis_pilaris

  Worldwide, KP affects an estimated 30 to 50% of the adult population, and around 50 to 80% of all adolescents. […] It is more common in women than in men, and it is often present in otherwise healthy individuals. […] The skin condition is prevalent in people of all ethnicities, and no particular ethnicity is at higher risk for developing KP. […] Although KP may manifest in people of any age, it usually appears within the first decade of life and is more common in young children. […] In most cases, the condition gradually improves before age 30, but it can persist longer.

• #7 Keratosis Pilaris: Symptoms and Treatment | Doctor

  https://patient.info/doctor/keratosis-pilaris-pro

  It affects nearly 50-80% of all adolescents and approximately 40% of adults. […] There is no racial bias but females are affected more often than males. […] It tends to present in the first decade of life. It may become worse in adolescence and often improves or disappears in adult life. […] Around half of cases have a positive family history.

• #8 Pediatric Keratosis Pilaris: Practice Essentials, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/910223-overview

  Keratosis pilaris is a very common disorder observed worldwide in both children and adults. […] The frequency of keratosis pilaris is increased in individuals with ichthyosis vulgaris, estimated at 74%. […] Many older reports claim an increased incidence in patients with atopic dermatitis, but more recent studies have not demonstrated this association. […] Given a high prevalence and intensity of keratosis pilaris noted during puberty and in women with hyperandrogenism, some experts postulate that keratosis pilaris may be influenced by hormonal changes. […] Keratosis pilaris has no known racial predilection. […] Keratosis pilaris affects both males and females. The inflammatory form of keratosis pilaris may be more prevalent in females. […] Keratosis pilaris most commonly develops during the first decade of life. It is estimated that 51% of cases are diagnosed during this period, while 35% are diagnosed during the second decade, 12% in the third decade, and 2% in the fourth decade.

• #9 Keratosis Pilaris: Symptoms, Causes, and Treatment

  https://www.webmd.com/skin-problems-and-treatments/keratosis-pilaris

  Keratosis pilaris is a common, harmless skin condition that causes small, hard bumps on your skin around clogged hair follicles. […] It’s a very common skin condition. About 50%-80% of teenagers will develop this condition in their teens. Among adults, about 40% will have it at some point in adulthood. […] The condition is more common among babies, toddlers, children, and teens. For most people, it either starts before the age of 2 or around your teen years. It may get worse in puberty, and then start to ease in your 20s. […] Certain things increase the risk of keratosis pilaris. You’re more likely to get it if you have: fair skin, hypothyroidism, Cushing’s disease, Down syndrome, diabetes, a close relative who has it, asthma, hay fever, dry skin, eczema, ichthyosis vulgaris, a condition that causes very dry skin, melanoma and are taking the drug vemurafenib.

• #10 What is keratosis pilaris? – Harvard Health

  https://www.health.harvard.edu/newsletter_article/By_the_way_doctor_What_is_keratosis_pilaris

  Keratosis pilaris affects as many as 40% of adults women more often than men. […] The condition tends to run in families, and genetic factors are probably involved. […] Keratosis pilaris tends to get worse in dry, cold weather and improve when warmth and humidity increase.

• #11

  https://www.hazanyderm.com/keratosis-pilaris-goose-bump-skin-treatment-dermatology-Los-Angeles-and-Beverly-Hills

  KP is more common in adolescents than in adulthood. According to epidemiology studies, KP affects roughly 50 to 80 percent of the worlds adolescent population, while it affects about 30 to 50 percent of the worlds adult population. […] KP is more prevalent in women than in men.

• #12 Keratosis Pilaris and Variants – Dermatology Advisor

  https://www.dermatologyadvisor.com/home/decision-support-in-medicine/dermatology/keratosis-pilaris-and-variants/

  Keratosis pilaris (KP) is a common disorder of keratinization of the hair follicles, characteristically affecting the posterolateral aspects of the upper arms and thighs. Because approximately 30%-50% of affected patients have a positive family history of keratosis pilaris, ichthyosis, or atopic dermatitis, it is important to inquire about family history. […] KP is a very common condition that affects people of any race and occurs worldwide. Both sexes are affected by KP, but females may be affected more frequently than males. Age of onset is in the first decade of life and symptoms may worsen during puberty. KP affects 50%-80% of all adolescents and approximately 40% of all adults; it frequently improves by age 30. Individuals may have a personal or family history of dry skin conditions such as ichthyosis or atopic dermatitis. Most individuals with KP are unaware they are affected or that treatment is available. […] Keratosis pilaris is thought to have an autosomal dominant inheritance with variable penetrance.

• #13 Keratosis pilaris – BAD Patient Hub

  https://www.skinhealthinfo.org.uk/condition/keratosis-pilaris/

  Keratosis pilaris (KP) is a very common skin condition, typically seen in children and young adults. It is harmless and affects more than half (50-70%) of teenagers and many (approximately 40%) adults. […] Keratosis pilaris may be associated with other skin diseases such as ichthyosis vulgaris and atopic eczema. […] Keratosis pilaris is harmless and is not infectious. […] It is usually found in more than one member of a family. The way it is inherited varies from family to family, but it often fits into an autosomal dominant pattern. This means that there will be a 1 in 2 chance that each child of an affected parent will inherit the condition. […] Treatments don’t clear keratosis pilaris completely, but they can improve the condition temporarily. Emollients (moisturisers) can help soften the texture of the skin. […] In many cases, it may be best to wait for the problem to improve on its own.

• #14 Integrative Dermatology Approaches to Keratosis Pilaris: Specialty Testing, Supplements, and Treatment

  https://www.rupahealth.com/post/integrative-dermatology-approaches-to-keratosis-pilaris-specialty-testing-supplements-and-treatment

  Keratosis pilaris is common, with an estimated 50 to 70 percent of all adolescents and 40 percent of adults experiencing the condition. […] Keratosis pilaris is most frequent in children and adolescents, reaching its peak prevalence in adolescence around puberty and often resolving by adulthood. […] In fact, 50-70% of people with keratosis pilaris have a genetic predisposition. […] Keratosis pilaris is also more common in people with various other skin diseases such as dry skin, atopic dermatitis or eczema, and ichthyosis, a condition where areas of skin are very dry and can have an appearance like fish scales. […] Age is another significant risk factor for keratosis pilaris. […] The rash of keratosis pilaris may get more intense during seasonal changes, during winter or in locations with low humidity, or in other conditions that worsen dry skin.

• #15 Keratosis pilaris | Description, Symptoms, & Treatment | Britannica

  https://www.britannica.com/science/keratosis-pilaris

  Keratosis pilaris is seen most commonly in young children and adolescents approximately 50-80 percent of adolescents are affected although it can occur at any age. […] It is more common among women than men. […] Persons affected by other skin conditions, especially eczema (atopic dermatitis) and ichthyosis vulgaris, are at increased risk of keratosis pilaris. […] The condition also is associated with light-coloured skin, diabetes mellitus, malnutrition, obesity, asthma, hypothyroidism, Cushing syndrome, hay fever, and certain genetic disorders, such as Down syndrome and Noonan syndrome. […] Persons who have a close relative with keratosis pilaris and melanoma patients who are treated with vemurafenib are also prone to developing the condition.

• #16 Keratosis pilaris | Tidsskrift for Den norske legeforening

  https://tidsskriftet.no/en/2023/03/clinical-review/keratosis-pilaris

  Keratosis pilaris is regarded as the most common follicular skin disease in children and occurs to a greater or lesser extent in 5080 % of adolescents and 40 % of adults (1, 35). It must therefore be considered to be a normal variant. Approximately 40 % of patients have a positive family history of the condition, which is thought to have an autosomal dominant inheritance with variable penetrance (1, 6). […] There are few Norwegian articles about keratosis pilaris, which is generally treated in the primary care service. This article is targeted at both general practitioners and doctors in the specialist health service and is based on a non-systematic literature search in PubMed and the authors’ clinical experience. […] Keratosis pilaris may be associated with overweight, diabetes and pregnancy (1), but since keratosis pilaris is so common, it is uncertain if there is any causal relationship. An association with several syndromes has also been reported, including Down’s syndrome, Noonan syndrome and cardiofaciocutaneous syndrome (1, 9). The latter two belong to the RASopathies and are caused by mutations in the genes involved in the RAS (rat sarcoma virus) signalling pathway, which is essential for regulation of cell growth and division. Keratosis pilaris is a significant finding in these syndromes, and keratosis pilaris atrophicans has been proposed as a potential marker for Noonan syndrome (1, 9, 10). In these cases, there will usually be symptoms from other organ systems in addition to the skin. Consideration should be given to genetic testing if the condition occurs in combination with extracutaneous manifestations and an underlying syndrome is suspected.

• #17 Keratosis Pilaris Treatment in Phoenix, AZ | Book Your Appointment

  https://saguaroderm.com/services/medical-dermatology/keratosis-pilaris/

  Keratosis pilaris is a common, harmless skin condition characterized by small, rough bumps on the skin. This condition is also known as “chicken skin” due to the goosebumps like appearance in the affected area. […] The buildup of keratin blocking the hair follicles is the main reason for the development of keratosis pilaris. Dry and low-humidity weather can make keratosis pilaris worse. This is why it is a common skin condition in Arizona. […] Although the exact reasons for the keratin build up is not well understood, dry weather and low humidity can worsen this condition. As Arizona has dry weather for the most part of the year, keratosis pilaris is common among people who live in Arizona.

• #18 Keratosis Pilaris: Symptoms, Causes, and Treatment

  https://www.webmd.com/skin-problems-and-treatments/keratosis-pilaris

  You don’t need to be tested for keratosis pilaris. Your doctor can diagnose it by looking at your skin. […] There’s no cure for keratosis pilaris. It usually clears up on its own over time. […] Keratosis pilaris doesn’t cause any harm to your body. The biggest complication may be that it makes you self-conscious about your appearance.

• #19 Keratosis Pilaris – almostadoctor

  https://almostadoctor.co.uk/encyclopedia/keratosis-pilaris

  80% of adolescents and 40% of adults […] Most patients are unaware or not bothered by the condition.

• #20 Intense Pulsed-light Therapy Significantly Improves Keratosis Pilaris: A Randomized, Double-blind, Sham Irradiation-controlled Trial | JCAD – The Journal of Clinical and Aesthetic Dermatology

  https://jcadonline.com/keratosis-pilaris-intense-pulsed-light/

  Keratosis pilaris (KP) is a common skin disorder, mostly seen in adolescents, with a prevalence of up to 50 percent in some populations. It is characterized by symmetrical, hyperkeratotic, follicular papules that contain keratinous plugs and twisted hairs. These papules are located predominantly on the extensor surfaces of the proximal extremities, such as the posterolateral upper arms, anterior thighs, and upper back. While KP is usually asymptomatic, it can have adverse psychological effects on those with the condition due to the disfiguring nature of the papules commonly located on visible areas. The pathogenesis of KP is largely unknown, yet it is considered a result of abnormal keratinization of the follicular epithelium and hair shaft defects. […] At the time of this articles publication, only one pilot study was found in the literature that evaluated the efficacy of IPL for the treatment of KP. A significant improvement of KP, measured with the Keratosis Pilaris Severity Index (KPSI), was reported in this study, yet some questions remain unanswered. In the present study, we investigated the efficacy of IPL, especially in terms of its effects on lesion roughness, perifollicular erythema, and hyperpigmentation.

• #21 Intense Pulsed-light Therapy Significantly Improves Keratosis Pilaris: A Randomized, Double-blind, Sham Irradiation-controlled Trial | JCAD – The Journal of Clinical and Aesthetic Dermatology

  https://jcadonline.com/keratosis-pilaris-intense-pulsed-light/

  Our study is the first that objectively evaluated skin roughness and demonstrated statistically and clinically significant reductions in skin roughness in subjects with KP treated with IPL. This is in clear contrast to sham irradiation. Although the absolute percentage change might not seem impressive, the clinical improvements were reported by subjects, reflected greater clinical improvement scores compared to the Antera3D imaging results. IPL therapy is also beneficial for KP-associated erythema and hyperpigmentation, as reported here. It is easy to deliver and covers large treatment areas within a reasonable treatment time. In terms of safety, our study demonstrated safety, with no major adverse events, using IPL therapy. […] We demonstrated that four monthly sessions of IPL therapy significantly improved KP in Thai subjects, particularly in regard to skin roughness. Our results indicate that this mode of treatment is safe and effective, suggesting that the IPL device could potentially be considered a first-line treatment option for KP. Additional randomized, controlled studies with larger patient samples and more diverse skin types are needed to support our findings.

• #22 Keratosis Pilaris: What It Is, Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/17758-keratosis-pilaris

  Keratosis pilaris is typically more common in babies, toddlers, children and teenagers, and it often worsens around puberty. […] Keratosis pilaris is so common that many dermatologists consider it a skin type instead of a medical condition. About 50% to 80% of teenagers and 40% of adults will develop these bumps at some point during their lives. […] Healthcare providers dont know why keratosis pilaris affects some people and not others. There could be a genetic factor, meaning your genes could affect your chances of developing this condition.

• #23 Keratosis pilaris

  https://pch.health.wa.gov.au/For-health-professionals/Referrals-to-PCH/Prereferral-guidelines/Keratosis-pilaris

  Keratosis pilaris is a common but harmless condition which results in rough, bumpy papules on the upper arms, thighs and less commonly on the face and back. […] It affects 50% to 80% of adolescents but can also occur in children and adults. […] Keratosis pilaris is, in most cases, a genetic condition and is more common in people with eczema. […] Routine referral of keratosis pilaris to PCH Dermatology is unlikely to be needed. […] Referral is warranted however if there is failure to conventional treatment listed above or if there is associated significant psychosocial impact.

• #24

  https://www.womenshealthmag.com/uk/beauty/skin/a61737426/keratosis-pilaris/

  Keratosis pilaris (KP) is a common skin condition that affects more than 40% of adults who live in the UK. […] While the cause of KP is not fully understood, it often runs in families and those with dry skin, or conditions like eczema, are more likely to develop it. […] Seeing a dermatologist or skin specialist is advisable if keratosis pilaris is severe, causing discomfort or if self-care measures haven’t improved the condition. A professional can prescribe stronger topical treatments or recommend procedures such as laser therapy. They can also provide personalised advice on skincare routines and procedures tailored to individual needs, says Dr Babamiri. […] Dr Leray also recommends seeing a dermatologist if your at-home skincare routine hasn’t improved your symptoms in four to six weeks.

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