Ehrlichioza i anaplazmoza
Zapobieganie i profilaktyka
Ehrlichioza i anaplazmoza to bakteryjne choroby przenoszone przez kleszcze, dla których nie istnieją szczepionki, co podkreśla znaczenie profilaktyki. U ludzi zaleca się stosowanie odzieży ochronnej (długie spodnie, rękawy, jasne kolory), aplikację repelentów zawierających DEET (do 30% u dzieci powyżej 2 miesięcy), pikarydynę lub IR3535 na odsłoniętą skórę oraz permetryny 0,5% na odzież i sprzęt. Kluczowe jest szybkie usunięcie kleszcza – w przypadku anaplazmozy w ciągu 12-24 godzin, a ehrlichiozy do 36 godzin od przyczepienia, przy użyciu pincety i zachowaniu ostrożności, aby nie ściskać ciała kleszcza. Po ukąszeniu nie zaleca się profilaktycznego podawania antybiotyków, lecz obserwację objawów przez 2 tygodnie i szybkie wdrożenie doksycykliny w razie podejrzenia zakażenia.
Ehrlichioza i anaplazmoza – Profilaktyka
Ehrlichioza i anaplazmoza to dwie ściśle powiązane choroby bakteryjne przenoszone przez kleszcze. Ze względu na brak dostępnych szczepionek przeciwko tym chorobom, zarówno u ludzi jak i zwierząt, kluczową rolę w zapobieganiu odgrywa profilaktyka ukierunkowana na unikanie ukąszeń kleszczy oraz szybkie ich usuwanie.12
Zapobieganie u ludzi
Profilaktyka ehrlichiozy i anaplazmozy u ludzi opiera się na kilku podstawowych zasadach, które pomagają w unikaniu kontaktu z kleszczami:34
- Stosowanie odpowiedniej odzieży ochronnej – długie spodnie wpuszczone w skarpety, długie rękawy, jasne kolory ułatwiające dostrzeżenie kleszczy
- Używanie repelentów zawierających DEET, pikarydinę lub IR3535 na odsłoniętą skórę (z wyjątkiem twarzy)
- Aplikowanie permetryny (0,5%) na odzież, buty i sprzęt turystyczny
- Poruszanie się po wyznaczonych ścieżkach podczas przebywania w terenach leśnych i trawiastych
- Regularne kontrolowanie ciała pod kątem obecności kleszczy, szczególnie w miejscach ciepłych i wilgotnych (pachy, pachwiny, szyja)
- Wzięcie prysznica tak szybko jak to możliwe po powrocie z terenów, gdzie mogą występować kleszcze
- Dokładne sprawdzanie zwierząt domowych, które mogą przenosić kleszcze do domu
Należy pamiętać o szczególnej ostrożności przy stosowaniu repelentów u małych dzieci. DEET powinien być używany ostrożnie u dzieci poniżej 2 miesięcy życia i w stężeniach nieprzekraczających 30% u starszych dzieci.16 Olejek z eukaliptusa cytrynowego (OLE) lub para-mentano-diol (PMD) nie powinny być stosowane u dzieci poniżej 3 lat.7
Prawidłowe usuwanie kleszczy
Wczesne i prawidłowe usunięcie kleszcza może znacząco zmniejszyć ryzyko zakażenia. Badania wykazały, że w przypadku anaplazmozy usunięcie kleszcza w ciągu 12-24 godzin od przyczepu, a w przypadku ehrlichiozy w ciągu 36 godzin, minimalizuje ryzyko infekcji.89 Zalecana procedura usuwania kleszcza obejmuje:1
- Użycie pincety o cienkich końcówkach
- Chwycenie kleszcza jak najbliżej powierzchni skóry
- Wyciągnięcie kleszcza powolnym, jednostajnym ruchem prostopadłym do skóry
- Unikanie ściskania ciała kleszcza, co mogłoby spowodować przedostanie się patogenów do skóry
- Zdezynfekowanie miejsca ukłucia alkoholem
- Nieużywanie wazeliny, zapałek ani innych środków drażniących kleszcze
Profilaktyka ehrlichiozy i anaplazmozy u zwierząt
Zapobieganie tym chorobom u zwierząt, szczególnie psów, koncentruje się na kontroli kleszczy oraz odpowiednim zarządzaniu środowiskiem.1112
Kontrola kleszczy u zwierząt
Najważniejsze metody zapobiegania ehrlichiozie i anaplazmozie u zwierząt obejmują:119
- Stosowanie skutecznych preparatów przeciwkleszczowych przez cały rok, nawet poza sezonem aktywności kleszczy
- Wykorzystanie obroży przeciwkleszczowych zawierających propoksur, amitraz lub flumetrynę, szczególnie w przypadku psów narażonych na infestację Rhipicephalus sanguineus
- Aplikowanie miejscowych środków przeciwkleszczowych (spot-on, pour-on) zgodnie z zaleceniami producenta
- Regularne sprawdzanie zwierząt pod kątem obecności kleszczy, szczególnie po spacerach
- Ograniczanie spacerów poza wyznaczonymi ścieżkami, w obszarach trawiastych i leśnych
- Usuwanie kleszczy najszybciej jak to możliwe, aby zapobiec przenoszeniu patogenów
Na rynku dostępnych jest wiele preparatów przeciwkleszczowych dla psów, w tym preparaty do stosowania miejscowego (Advantix, Frontline Plus, Vectra 3D, Bravecto), preparaty doustne (Nexgard, Simparica, Credelio, Bravecto) oraz obroże przeciwkleszczowe (np. Seresto, które mogą być skuteczne do 8 miesięcy).13 Wybór konkretnego produktu powinien być skonsultowany z lekarzem weterynarii i dostosowany do indywidualnych potrzeb zwierzęcia.
Kontrola środowiska
Redukcja populacji kleszczy w środowisku jest również ważnym elementem profilaktyki:912
- Utrzymywanie trawy nisko przyciętej (poniżej 5 cali)
- Regularne usuwanie opadłych liści i gałęzi
- Ograniczanie dostępu dzikich zwierząt, które mogą być nosicielami kleszczy
- Modyfikacja siedlisk wokół domu poprzez przycinanie krzewów i zarośli
- Tworzenie barier fizycznych między obszarami naturalnymi a terenami rekreacyjnymi
Szczególnie trudne może być kontrolowanie infestacji R. sanguineus (kleszcz psi) w hodowlach i w pobliżu domów, gdyż gatunek ten może zadomowić się w pomieszczeniach i być aktywny przez cały rok. W takich przypadkach długoterminowa kontrola kleszczy jest niezbędna dla skutecznego zarządzania problemem.119
Profilaktyka farmakologiczna
Profilaktyka u ludzi
W przypadku ludzi, stosowanie antybiotyków jako profilaktyki po ukąszeniu kleszcza nie jest zalecane w zapobieganiu ehrlichiozie i anaplazmozie.1617 Zamiast tego, osoby ukąszone przez kleszcze powinny uważnie obserwować swój stan zdrowia i skontaktować się z lekarzem w przypadku wystąpienia objawów takich jak gorączka, wysypka czy ból głowy w ciągu 2 tygodni od ukąszenia.1618
Szybkie wdrożenie leczenia doksycykliną w przypadku podejrzenia zakażenia jest kluczowe dla zapobiegania poważnym powikłaniom i nigdy nie powinno być opóźniane w oczekiwaniu na wyniki badań laboratoryjnych.1719
Profilaktyka u zwierząt
W przeciwieństwie do ludzi, profilaktyczne podawanie tetracyklin może być stosowane u psów w określonych sytuacjach. Profilaktyczne podawanie tetracykliny w niższej dawce (6,6 mg/kg/dzień, doustnie) jest skuteczne w zapobieganiu zakażeniom E. canis w hodowlach, gdzie choroba występuje endemicznie.1120 Leczenie musi być kontynuowane przez wiele miesięcy, co najmniej przez jeden sezon aktywności kleszczy, jeśli cykl endemiczny ma zostać skutecznie przerwany, a kontrola kleszczy powinna być jednocześnie wdrożona.11
Długoterminowa profilaktyka tetracykliną (6,6 mg/kg raz dziennie), repozytoryjną oksytetracykliną (200 mg domięśniowo dwa razy w tygodniu) lub doksycykliną była stosowana u psów służbowych lub psów utrzymywanych w hodowlach zainfestowanych kleszczami, aby zapobiec ehrlichiozie podczas przebywania w regionach endemicznych dla kleszczy.20
Warto zauważyć, że po terapeutycznej eliminacji Ehrlichia spp., psy nie rozwijają odporności ochronnej i mogą zostać ponownie zakażone po ponownym kontakcie z kleszczem przenoszącym patogen.2021
Zapobieganie przenoszeniu przez transfuzje
Przenoszenie ehrlichiozy i anaplazmozy może również nastąpić poprzez transfuzję krwi od zakażonych dawców. Aby zapobiec temu sposobowi transmisji, zaleca się:11
- Używanie seronegatywnych, przebadanych dawców krwi
- Świadomość, że nowi dawcy z negatywnym wynikiem badania przesiewowego nie mogą być uznani za wolnych od zakażenia przez kilka tygodni, ponieważ mogą inkubować infekcję
- Regularne badania dawców krwi pod kątem patogenów przenoszonych przez kleszcze
Monitorowanie zwierząt seropozytywnych
W przypadku psów z pozytywnym wynikiem badania przesiewowego w kierunku Ehrlichia spp., ale bez objawów klinicznych, istnieją trzy główne podejścia:21
- Poprawa kontroli ektopasożytów – zawsze wskazana niezależnie od wybranego podejścia terapeutycznego
- Podanie antybiotyków (doksycyklina) – może zmniejszyć ryzyko rozwoju choroby przewlekłej, choć 28-dniowy kurs tetracyklin może nie eliminować całkowicie patogenów Ehrlichia
- Podejście „obserwuj i czekaj” – ponieważ wiele psów zakażonych E. canis może pozostać zdrowych i nigdy nie rozwinąć choroby przewlekłej
Bez względu na wybrane podejście, psy z dodatnim wynikiem badania serologicznego powinny być monitorowane co najmniej raz w roku.21 Pozytywny wynik badania w kierunku Ehrlichia powinien również skłaniać do ponownej oceny i poprawy metod kontroli ektopasożytów stosowanych przez właściciela.21
Edukacja i świadomość
Edukacja właścicieli zwierząt i ogółu społeczeństwa na temat zagrożeń związanych z kleszczami jest istotnym elementem skutecznej profilaktyki:2223
- Informowanie o występowaniu chorób przenoszonych przez kleszcze w danym regionie
- Edukacja na temat prawidłowego usuwania kleszczy
- Promowanie regularnych badań przesiewowych zwierząt domowych w kierunku chorób przenoszonych przez kleszcze
- Zwiększanie świadomości na temat objawów ehrlichiozy i anaplazmozy, aby umożliwić wczesne rozpoznanie i leczenie
Właściciele zwierząt powinni być świadomi, że wcześniejsze zakażenie nie zapobiega ponownemu zakażeniu, a drugie zakażenie może wywołać chorobę nawet jeśli początkowe zakażenie nie spowodowało objawów klinicznych.21
Pracownicy służby zdrowia i lekarze weterynarii powinni być przeszkoleni w zakresie rozpoznawania, diagnozowania i leczenia ehrlichiozy i anaplazmozy, zwłaszcza w regionach, gdzie choroby te stają się coraz bardziej powszechne.23
Specjalne grupy ryzyka
Niektóre grupy ludzi i zwierząt są szczególnie narażone na zakażenie ehrlichiozą i anaplazmozą:243
- Osoby pracujące na zewnątrz, zwłaszcza w lasach, parkach i terenach zielonych
- Osoby uprawiające turystykę pieszą, kemping lub inne aktywności na świeżym powietrzu w obszarach występowania kleszczy
- Psy służbowe i pracujące, które spędzają dużo czasu na zewnątrz
- Zwierzęta przebywające w regionach endemicznych dla kleszczy
- Zwierzęta z dostępem do obszarów zalesionych, trawiastych lub zaroślowych, gdzie populacje kleszczy mogą być liczne
Dla tych grup wskazane jest stosowanie dodatkowych środków ostrożności, takich jak częstsze kontrole pod kątem kleszczy, stosowanie silniejszych repelentów i konsekwentne stosowanie środków ochrony osobistej lub środków przeciwkleszczowych.2419
Podsumowanie zasad profilaktyki
Skuteczna profilaktyka ehrlichiozy i anaplazmozy wymaga kompleksowego podejścia obejmującego:1226
- Unikanie obszarów występowania kleszczy, zwłaszcza w okresach ich wzmożonej aktywności
- Stosowanie odpowiedniej odzieży ochronnej i repelentów
- Regularne kontrole ciała pod kątem obecności kleszczy i ich szybkie usuwanie
- Stosowanie skutecznych środków przeciwkleszczowych u zwierząt domowych przez cały rok
- Modyfikację środowiska w celu zmniejszenia populacji kleszczy
- Edukację i zwiększanie świadomości na temat zagrożeń związanych z kleszczami
- W przypadku hodowli psów z endemiczną ehrlichiozą – rozważenie profilaktycznego stosowania tetracyklin pod nadzorem lekarza weterynarii
Należy pamiętać, że w przypadku ehrlichiozy i anaplazmozy profilaktyka jest zdecydowanie skuteczniejsza niż leczenie. Jak podkreślają eksperci: „w przypadku kleszczy, najlepszym lekarstwem jest zapobieganie!”2427
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Materiały źródłowe
- #1 Ehrlichiosis and Anaplasmosis – Infectious Diseases – Merck Manual Professional Editionhttps://www.merckmanuals.com/professional/infectious-diseases/rickettsiae-and-related-organisms/ehrlichiosis-and-anaplasmosis
No vaccine is available to prevent ehrlichiosis or anaplasmosis. Measures can be taken to prevent tick bites. […] Preventing tick access to skin includes staying on paths and trails, tucking trousers into boots or socks, wearing long-sleeved shirts, and applying repellents with diethyltoluamide (DEET) to skin surfaces. […] DEET should be used cautiously in very young children because toxic reactions have been reported. Permethrin on clothing effectively kills ticks. Frequent searches for ticks, particularly in hairy areas and on children, are essential in endemic areas. […] Engorged ticks should be removed with care and not crushed between the fingers because crushing the tick may result in disease transmission. The ticks body should not be grasped or squeezed. Gradual traction on the head with a small forceps dislodges the tick. The point of attachment should be swabbed with alcohol. Petroleum jelly, lit matches, and other irritants are not effective ways to remove ticks and should not be used. […] No practical means are available to rid entire areas of ticks, but tick populations may be reduced in endemic areas by controlling small-animal populations.
- #2 About Anaplasmosis | Anaplasmosis | CDChttps://www.cdc.gov/anaplasmosis/about/index.html
There is no vaccine to prevent anaplasmosis. Prevent illness by preventing tick bites, preventing ticks on your pets, and preventing ticks in your yard.
- #3 Ehrlichiosis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK441966/
Patients should be educated on best practices for tick prevention. There is no human-to-human transmission of ehrlichiosis. The most important deterrent is the prevention of tick bites, especially in endemic areas. Wearing protective clothing, such as long pants tucked into socks, is essential to minimize skin exposure.[49] […] In addition to clothing, repellants are mandatory when performing outdoor activities. Effective repellants include N,N-diethyl-meta-toluamide, picaridin, and IR3535. Daily body checks for ticks, especially in warm, moist areas, such as the axillae, groin, and neck, are important for early detection and removal of ticks.[49][50][49] […] There is no vaccine available for any of the Ehrlichia species. Avoiding tick bites remains the mainstay of prevention, with insect repellents, avoiding high-risk areas, covering all exposed skin, and checking carefully for ticks after outdoor activities in endemic areas. As ehrlichiosis is not transmitted directly person-to-person, no isolation is needed.
- #4 Ehrlichiosis and anaplasmosis – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/ehrlichiosis/symptoms-causes/syc-20372142
The best way to prevent these infections is to avoid tick bites. Tick repellents, thorough body checks after being outside and proper removal of ticks are your best defenses against these tick-borne diseases. […] If you are going to be working or playing in an area that is a likely tick habitat, follow these tips to protect yourself. […] Using insect repellents is a good idea. […] Use permethrin on materials and DEET on skin. […] Spray your outdoor clothing, shoes, tent or other camping gear with a repellent that has 0.5% permethrin. […] Use an insect repellent registered with the Environmental Protection Agency on any exposed skin, except your face. […] Wear light-colored clothing that makes it easier for you or others to see ticks on your clothing before they bite. […] Shower as soon as possible to wash off any loose ticks and check for ticks that may have burrowed. […] Do a daily inspection for ticks on any pet that spends time outdoors. […] Stay on clear paths as much as possible in wooded and grassy areas.
- #5 Ehrlichiosis Treatment & Management: Approach Considerations, Deterrence and Prevention, Consultationshttps://emedicine.medscape.com/article/235839-treatment
Deterrence and prevention of ehrlichiosis includes the following: […] Wear light-colored clothes […] Tuck pants into socks […] Use insect repellent […] Regularly examine the body for ticks […] Promptly remove ticks; a feeding period of 3-48 h is required before disease is transmitted. […] Cover exposed areas of the skin with insect repellents containing N,N -diethyl-meta-toluamide (DEET). […] In children, carefully use insect repellents on exposed skin; avoid the face and hands to prevent systemic absorption. […] After returning from wooded and/or tick-infested areas, individuals should check themselves carefully for ticks. […] If found, ticks should be removed carefully and a physician should be consulted. […] No role exists for the use of antimicrobial prophylaxis after a tick bite in the prevention of human monocytic ehrlichiosis (HME) or human granulocytic anaplasmosis (HGA) due to the low rate of subsequent infection.
- #6 Anaplasmosis (HGA) | Mass.govhttps://www.mass.gov/info-details/anaplasmosis-hga
HGA can be treated with antibiotics. It is important to begin treatment early to prevent serious, potentially life-threatening complications. […] Prevention begins with you! Take steps to reduce your chances of being bitten by any tick. Ticks are most active during warm weather, generally late spring through fall. However, ticks can be out any time that temperatures are above freezing. Ticks cling to vegetation and are most numerous in brushy, wooded or grassy habitats. When you are outside in an area likely to have ticks (e.g. brushy, wooded or grassy places), follow these simple steps to protect yourself and your loved ones: […] Use a repellent with DEET (the chemical N,N-Diethyl-meta-toluamide) or permethrin. Repellents containing DEET should not be used on children less than 2 months of age and should be used in concentrations no higher than 30% on older children. Permethrin products are intended for use on items such as clothing, shoes, bed nets and camping gear and should not be applied to skin. Other repellents, such as picaridin, oil of lemon eucalyptus and IR 3535, have also been found to provide protection against ticks.
- #7 Mayo Clinic Health Library – Ehrlichiosis and anaplasmosis | Swiss Medical Networkhttps://www.swissmedical.net/fr/healtcare-library/con-20372124
Use an insect repellent registered with the Environmental Protection Agency on any exposed skin, except your face. These include repellents that contain DEET, picaridin, IR3535, oil of lemon eucalyptus (OLE), para-menthane-diol (PMD) or 2-undecanone. […] Do not use products with OLE or PMD on children under age 3. […] Wear light-colored clothing that makes it easier for you or others to see ticks on your clothing before they bite. […] Avoid open-toed shoes or sandals. […] Wear long-sleeved shirts tucked into your pants and long pants tucked into your socks. […] Shower as soon as possible to wash off any loose ticks and check for ticks that may have burrowed. […] Use a mirror to check your body thoroughly. Pay attention to your underarms, hair and hairline, ears, waist, between your legs, behind your knees, and inside your bellybutton. […] Check your gear. Dry your clothes and gear on hot for at least 10 minutes to kill ticks before cleaning them. […] Do a daily inspection for ticks on any pet that spends time outdoors. […] Stay on clear paths as much as possible in wooded and grassy areas.
- #8 Anaplasmosis and Ehrlichiosis Fact Sheethttps://www.health.ny.gov/diseases/communicable/ehrlichiosis/fact_sheet.htm
Anaplasmosis and Ehrlichiosis are two closely related tick-borne bacterial diseases spread by the bite of infected ticks. […] The best prevention to either disease is through awareness. Check after every two to three hours of outdoor activity for ticks on clothing or skin. Brush off any ticks on clothing before skin attachment occurs. With anaplasmosis, if removal of attached ticks occurs within 12 hours the risk of tick-borne infection is minimal. For ehrlichiosis, if removal of attached ticks occurs within 36 hours the risk of tick-borne infection is minimal. […] Insect repellents can be effective at reducing bites from ticks that can spread disease. If you decide to use a repellent, use only what and how much you need for your situation. […] Be sure to follow label directions. […] Domestic animals can carry ticks into areas where you live so it is important to check pets for ticks before they enter the home.
- #9 Guideline for veterinary practitioners on canine ehrlichiosis and anaplasmosis in Europe | Parasites & Vectors | Full Texthttps://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-015-0649-0
Apart from appropriate epidemiological measures, the best prevention against dog tick infestation is based on the use of ectoparasiticides. In general, these are active molecules that act against ticks, and they must also provide some degree of appropriate control within a short period of time. Rapid action could contribute to the elimination of attached ticks before they are able to transmit pathogens. To optimize efficacy, preventive chemicals must be applied at the recommended time intervals, based on the length of efficacy claimed by the manufacturer. Although knowledge may be lacking for some diseases, most tick-borne pathogens require 4 to 48 h to complete their development in the salivary gland and enter the bloodstream. However, a recent report showed that transmission of E. canis can occur within shorter periods of time (e.g., 3 h).
- #9 Guideline for veterinary practitioners on canine ehrlichiosis and anaplasmosis in Europe | Parasites & Vectors | Full Texthttps://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-015-0649-0
The prevention of ehrlichiosis and/or anaplasmosis infections in dogs must be focused on tick control. Ticks of the R. sanguineus complex are mainly found indoors, but other populations of the tick may be common in gardens, pastures, and fields in the Mediterranean basin. Therefore, dogs may become infected with the most common tick present in infested private gardens or kennels, but also, whenever they are engaged in an activity that involves contact with natural green areas. Nevertheless, to prevent transmission, actions must focus mainly on: […] preventing dogs from becoming infested in the field, which is the source of peridomestic parasitism. This infestation can introduce ticks to indoor habitats (kennels, etc.), which will result in a large population, due to their high reproductive capacity.
- #9 Guideline for veterinary practitioners on canine ehrlichiosis and anaplasmosis in Europe | Parasites & Vectors | Full Texthttps://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-015-0649-0
preventing dogs from becoming infested with ticks, even when they live in a peridomestic environment with abundant ticks. This objective is more difficult to achieve than the former, due to the high parasitism pressure that can arise from those populations of ticks. […] To appropriately control tick infestations in dogs requires knowledge of tick seasonality. This seasonality is usually strict under natural conditions, and each stage of the life cycle of the tick follows the previous stage with regularity. However, these patterns can be lost in areas with large infestations in a peridomestic environment. Under those conditions, all stages can be active simultaneously, due to the presence of several infestations in the kennel. […] Various antiparasitic treatments are registered in Europe that have activity against ticks and can be prescribed for dogs. The specific product can be selected according to the preferences of use (collar, pour-on, or spot on) and the therapeutic needs for each case. Some compounds, such as the pyrethroids or some preparations of diazinon, are registered as repellents.
- #10 Ehrlichiosis: MedlinePlus Medical EncyclopediaLockhttps://medlineplus.gov/ency/article/001381.htm
If possible, ask someone to help you examine your body for ticks. […] An adult should examine children carefully. […] Studies suggest that a tick must be attached to your body for at least 24 hours to cause disease. Early removal may prevent infection. […] If you are bitten by a tick, write down the date and time the bite happened. Bring this information, along with the tick (if possible), to your provider if you become sick.
- #11 Ehrlichiosis, Anaplasmosis, and Related Infections in Animals – Infectious Diseases – MSD Veterinary Manualhttps://www.msdvetmanual.com/generalized-conditions/rickettsial-diseases/ehrlichiosis-anaplasmosis-and-related-infections-in-animals
Prevention of ehrlichiosis and anaplasmosis is accomplished by controlling ticks on dogs. Dogs in areas infested by ticks should be limited from walking off-trail, in certain grassy areas, and where there may be ticks in some leaf litter. They should be examined after walks, with ticks removed carefully (to prevent human exposure), although it is unrealistic that owners will find all ticks in the coat of a dog. Multiple topical medications are available to prevent tick bites, and these should be used in compliance with labeling before bringing dogs into areas infested with ticks. Because R sanguineus infestations can be problematic in kennels and around homes, and longterm tick control is needed for management, use of effective long-acting collars on all susceptible dogs might be considered; collars containing propoxur, amitraz, or flumethrin have proven activity against R sanguineus.
- #11 Ehrlichiosis, Anaplasmosis, and Related Infections in Animals – Infectious Diseases – MSD Veterinary Manualhttps://www.msdvetmanual.com/generalized-conditions/rickettsial-diseases/ehrlichiosis-anaplasmosis-and-related-infections-in-animals
Prevention of transfusion-associated transmission can be reduced by using seronegative screened blood donors, although new donors with a negative screen cannot be presumed free of infection for several weeks because they may be incubating infection. Prophylactic administration of tetracycline at a lower dosage (6.6 mg/kg/day, PO) is effective in preventing E canis infection in kennels where disease is endemic. Treatment must be extended for many months through at least one tick season if the endemic cycle is to be successfully eliminated, and tick control should be implemented as well.
- #12 Companion Animal Parasite Council | Ehrlichia spp. and Anaplasma spp.https://capcvet.org/guidelines/ehrlichia-spp-and-anaplasma-spp/
Screening dogs for exposure to the agents of ehrlichiosis and anaplasmosis to identify dogs at risk of disease. […] Reducing risk of infection through year-round tick control and avoiding areas with ticks. […] Vaccines are not available to prevent infection of pets by Ehrlichia spp. and Anaplasma spp. pathogens. Stringent adherence to routine application of effective acaricides is critical for preventing infection and disease caused by these organisms. […] Various stages and species of ticks are active at different times of the year in different parts of the country. Because tick activity may occur year-round and pets may travel to areas where ticks are active, CAPC recommends that all pets be maintained on tick-control products year-round. […] Tick infestations and resultant infection with Ehrlichia spp. and Anaplasma spp. can be prevented by avoiding tick-infested areas whenever possible and by modifying the habitat around the home through such basic measures as keeping shrubbery and grass closely clipped to discourage both tick populations and the wildlife species that often harbor them from flourishing.
- #13 Ehrlichiosis in Dogs | VCA Animal Hospitalshttps://vcahospitals.com/know-your-pet/ehrlichiosis-in-dogs
Ridding the dog’s environment of ticks and applying flea and tick preventives are the most effective means of prevention. […] Topical options include Advantix, Frontline Plus, Vectra 3D or Bravecto. […] Oral chewable options include Nexgard, Simparica, Credelio, or Bravecto. […] There is also the Seresto collar that can be effective for up to eight months. […] As new products are constantly being developed, your veterinarian will help you determine which preventive is best for your dog.
- #14 Battling Tick-Borne Diseases: A Focus on Ehrlichiosis and Anaplasmosishttps://www.tallyoaksvet.com/services/dogs/blog/battling-tick-borne-diseases-focus-ehrlichiosis-and-anaplasmosis
Based on an article that first appeared at Aspen Veterinary Clinic […] Preventative measures play a key role in managing the risk associated with these diseases. […] Preventative Treatments: Utilizing tick preventatives such as specific topical solutions (most over the counter topicals do not kill ticks fast enough to prevent the spread of disease) or oral medications is crucial. These preventatives should be used year-round. […] Regular Tick Checks: After any outdoor activities, itâs essential to check your dog for ticks. Pay close attention to areas like the ears, neck, and between the toesâfavorite spots for ticks to latch on. […] Environmental Management: Trimming your yard and clearing it of excessive leaf litter or tall grasses can significantly reduce the tick population in your immediate environment.
- #15 Ehrlichiosis: Causes, Symptoms, Treatment & Preventionhttps://my.clevelandclinic.org/health/diseases/17958-ehrlichiosis
Avoiding tick bites is the best way to reduce your risk of ehrlichiosis. […] Keep grass cut shorter than 5 inches. […] Stay on cleared paths while in wooded areas. […] Use bug sprays with DEET or other ingredients approved to keep ticks away. […] Use clothing to cover as much of your skin as possible when you’re in the woods or areas with long grass. You can buy special tick-repellant clothing if you’re often in areas with ticks. […] Check yourself for ticks after you’ve been outside. If possible, have someone else check you in places you can’t see yourself (like your back and scalp). […] Ask your veterinarian about the best way to protect your pets from ticks. Check your pets for ticks often, especially after they’ve been outside. […] Follow directions for safely removing a tick if you find one on you.
- #16 Clinical Care of Ehrlichiosis | Ehrlichiosis | CDChttps://www.cdc.gov/ehrlichiosis/hcp/clinical-care/index.html
Doxycycline prophylaxis is not recommended. […] Antibiotic prophylaxis after a tick bite is not recommended to prevent ehrlichiosis. […] People who have been bitten by a tick should watch for signs and symptoms. They should see their healthcare provider if fever, rash, headache or other symptoms develop within 2 weeks of tick bite.
- #17 Health: Infectious Disease Epidemiology & Prevention Division: Anaplasmosishttps://www.in.gov/health/idepd/zoonotic-and-vectorborne-epidemiology-entomology/zoonotic-diseases/anaplasmosis/
The best way to prevent anaplasmosis is to avoid tick bites. Please see our tick prevention page for more information. […] While post-tick bite antibiotic prophylaxis is not recommended to prevent anaplasmosis, treatment should be started for anyone with suspected anaplasmosis (patients with a compatible clinical illness) and should never be delayed while waiting for laboratory results.
- #18 Ehrlichiosis Medication: Antibioticshttps://emedicine.medscape.com/article/235839-medication
Currently, there is no recommendation for the use of doxycycline or other antibiotics for post tick exposure prophylaxis against HME or HGA. Individuals with potential tick-bite exposure should monitor for development of symptoms such as feeling unwell, fever, new rash within 2 weeks of exposure and contact their healthcare providers for further evaluation.
- #19 Colorado Tick-Borne Disease Awareness Association (COTBDAA) – Education, Prevention, Research and Advocacy – Ehrlichiosishttps://coloradoticks.org/what-is-ehrlichiosis/
Ehrlichiosis is a serious illness that can be fatal if not treated correctly, even in previously healthy people. […] Early treatment with the antibiotic doxycycline can prevent death and severe illness. Doxycycline is the recommended antibiotic treatment for ehrlichiosis in adults and children of all ages. […] Preventing Tick Bites. […] Daily Tick Checks! […] How to Properly Remove a Tick. […] Risks for Outdoor Workers.
- #20https://www.vin.com/apputil/content/defaultadv1.aspx?id=5124317&pid=11343
Tick-borne pathogens are of tremendous historical importance to both veterinary and human medicine. […] Therefore, so as to decrease disease transmission, drug manufacturers should continue to search for effective acaricides and products with strong repellent characteristics, so as to prevent tick attachment and the need to treat ehrlichiosis in pets. […] Long-term tetracycline prophylaxis (6.6 mg/kg once daily), repositol oxytetracycline (200 mg IM twice weekly) or doxycycline have been utilized in military working dogs or dogs maintained in tick infested kennels to prevent ehrlichiosis during deployment to tick endemic regions. […] Following therapeutic elimination of Ehrlichia spp., dogs do not develop protective immunity and can be re-infected when re-introduced to a vector-competent tick.
- #21 What to Do With the Ehrlichia-Positive Healthy Doghttps://todaysveterinarypractice.com/parasitology/what-to-do-with-the-ehrlichia-positive-healthy-dog/
A positive Ehrlichia screening result should prompt a conversation with the pet owner about their ectoparasite control measures. […] A positive Ehrlichia screening result should prompt reevaluation of ectoparasite control with the pet owner. […] Pet owners should also be made aware that prior infection does not prevent future reinfection, and second infections might cause disease even if the initial infection did not. […] Not only did their dog have a tick, but that tick infected it with a pathogen. A positive result clearly demonstrates that tick control must be stepped up. […] Check pets daily for ticks, especially around the ears and eyes, between the legs and toes, around the tail, and under the collar. Perform tick checks even when using tick prophylaxis, as no prophylaxis is perfectly effective.
- #21 What to Do With the Ehrlichia-Positive Healthy Doghttps://todaysveterinarypractice.com/parasitology/what-to-do-with-the-ehrlichia-positive-healthy-dog/
Use appropriate tick prophylaxis for all dogs and cats in the home. […] Administering antibiotics has the potential benefit of reducing the risk of development of chronic disease. However, there is evidence that a 28-day course of tetracyclines may not eliminate Ehrlichia pathogens. […] Because elimination of the organism is not certain, even dogs treated with antimicrobials should be monitored on at least a yearly basis as with the âwatch and waitâ approach. […] The third option for these healthy animals would be to adopt a watch-and-wait approach. Because many dogs infected with E canis might remain healthy and never develop chronic disease, and dogs infected with E ewingii or E chaffeensis are unlikely to develop chronic disease, simply monitoring the dog may be adequate. […] Positive screening serologic test results for Ehrlichia species exposure in dogs requires veterinarians to make decisions as to next steps, taking into consideration geography and prevalence of pathogens in the area, individual animal factors, and owner wishes. Reevaluation of ectoparasite prevention is always appropriate.
- #22 AKC Canine Health Foundation | Tick-borne Disease: Prevalence, Prevention, and Treatmenthttps://www.akcchf.org/canine-health/sporting-field-dogs/tick-borne-disease.html
Keep Your Dog Safe from Tick-borne Disease […] Use preventives, including topical medication and tick collars. Be aware that tick preventatives do not prevent disease transmission; they reduce risk by reducing the tick burden in the dogs environment. […] Talk to your veterinarian about annual testing for tick-borne disease. Testing is fast, effective, and can save costly veterinary bills of disease is not caught in its early stages. […] Anaplasma phagocytophilum is transmitted by the deer tick and the western black-legged tick. These are the same ticks that transmit Lyme disease which increases the risk of co-infection with multiple tick-borne diseases. […] Anaplasma platys is transmitted by the brown dog tick.
- #23 New Training on Ehrlichiosis and Anaplasmosis Available from CDC | SDAHOhttps://sdaho.org/2022/05/26/new-training-on-ehrlichiosis-and-anaplasmosis-available-from-cdc/?utm_source=rss&utm_medium=rss&utm_campaign=new-training-on-ehrlichiosis-and-anaplasmosis-available-from-cdc
New Training on Ehrlichiosis and Anaplasmosis Available from CDC […] Tickborne diseases are on the rise in the United States with reported cases of ehrlichiosis and anaplasmosis are increasing in numbers and geographic range. […] Providers and public health practitioners need to be aware of these emerging issues and understand that early recognition, treatment, and diagnosing effectively can prevent severe and fatal outcomes. […] The Centers for Disease Control and Prevention (CDC) recently issued a new training module on the diagnosis and treatment of ehrlichiosis and anaplasmosis with opportunities for continuing education in seven professional categories, such as Continuing Medical Education (CME), Continuing Nursing Education (CNE), Continuing Education Units (CEU), and Continuing Education Contact Hours (CECH). […] Key learning points covered in the module include: […] Disease prevention. […] This approximate 1 hour training comes at an opportune time as warmer weather approaches and outdoor activities increase.
- #24 Battling Tick-Borne Diseases: A Focus on Ehrlichiosis and Anaplasmosishttps://www.allcreaturesvetcare.com/services/dogs/blog/battling-tick-borne-diseases-focus-ehrlichiosis-and-anaplasmosis
Preventative measures play a key role in managing the risk associated with these diseases. […] Utilizing tick preventatives such as specific topical solutions (most over the counter topicals do not kill ticks fast enough to prevent the spread of disease) or oral medications is crucial. […] Regular veterinary check-ups, preventive medications, and environmental management are our best tools in preventing Ehrlichiosis and Anaplasmosis, among other tick-borne diseases. […] Remember, when it comes to ticks, the best cure is prevention!
- #24 Battling Tick-Borne Diseases: A Focus on Ehrlichiosis and Anaplasmosishttps://www.allcreaturesvetcare.com/services/dogs/blog/battling-tick-borne-diseases-focus-ehrlichiosis-and-anaplasmosis
Based on an article that first appeared at Aspen Veterinary Clinic Every year, countless dogs across the United States are bitten by ticks. […] The prevalence of ticks and tick-borne diseases has been on the rise, largely due to factors like climate change and urban sprawl encroaching on natural tick habitats. […] Most have heard of Lyme disease, especially those in the Eastern part of the country, but I want to focus on Ehrlichiosis and Anaplasmosis as these diseases kill numerous pets every year in Northern Arizona and yet are nearly 100% preventable. […] This is why parasite preventatives, as well as prompt tick removal, are essential preventive measures. […] Pets that spend significant time outdoors, especially wooded, grassy, or bushy areas where tick populations thrive, are at a higher risk.
- #25 Tick-borne Diseases | Washington State Department of Healthhttps://doh.wa.gov/you-and-your-family/illness-and-disease-z/tick-borne-diseases
The best way to protect yourself and others against tick-borne disease is by reducing your exposure to ticks and preventing ticks from biting. […] If you or your family member develops symptoms of anaplasmosis and were recently bitten by a tick or were in brushy areas where ticks commonly live, visit your healthcare provider or contact your local health department. […] If you or your family member develops symptoms of ehrlichiosis and were recently bitten by a tick or were in brushy areas where ticks commonly live, visit your healthcare provider or contact your local health department.
- #26 Do I Need to Worry About Ehrlichiosis & Anaplasmosis? | IGeneX | Tick Talkhttps://igenex.com/tick-talk/ehrlichiosis-anaplasmosis-do-i-need-to-worry/
Ehrlichiosis and Anaplasmosis are often grouped and referred to together due to their similarities. […] Whether or not someone should be worried about Ehrlichiosis or Anaplasmosis heavily depends on how careful they are when spending time outdoors. […] Even outside of their regional territories, being aware of the potential hazards that ticks present and avoiding them is the best way to protect against Ehrlichiosis, Anaplasmosis, and other tick-borne diseases. […] When hiking, gardening, or otherwise engaging in outdoor activities, take care to tuck in long clothing and use a protective repellent to avoid tick bites. […] Like other tick-borne diseases, there is no vaccine to prevent Anaplasmosis or Ehrlichiosis. The best way to prevent these diseases is to avoid tick bites in the first place.
- #27 Battling Tick-Borne Diseases: A Focus on Ehrlichiosis and Anaplasmosishttps://www.aspenvetflagstaff.com/services/dogs/blog/battling-tick-borne-diseases-focus-ehrlichiosis-and-anaplasmosis
Ehrlichiosis and Anaplasmosis are diseases caused by rickettsial organisms, which are bacterial pathogens that predominantly affect blood cells. They are transmitted by ticks, making any pet with outdoor exposure potentially at risk. […] This is why parasite preventatives, as well as prompt tick removal, are essential preventive measures. […] Preventative measures play a key role in managing the risk associated with these diseases. […] Utilizing tick preventatives such as specific topical solutions (most over the counter topicals do not kill ticks fast enough to prevent the spread of disease) or oral medications is crucial. These preventatives should be used year-round. […] Regular veterinary check-ups, preventive medications, and environmental management are our best tools in preventing Ehrlichiosis and Anaplasmosis, among other tick-borne diseases. […] Remember, when it comes to ticks, the best cure is prevention!