Drgawki toniczno-kloniczne (drgawki duże)
Objawy

Drgawki toniczno-kloniczne, dawniej określane jako napady grand mal, to uogólnione napady padaczkowe obejmujące obie półkule mózgowe, charakteryzujące się fazą toniczną (10-20 sekund) z gwałtownym usztywnieniem mięśni oraz fazą kloniczną (1-2 minuty) z rytmicznymi skurczami mięśni. Całkowity czas napadu wynosi zwykle 1-3 minuty. Przed napadem mogą wystąpić objawy prodromalne i aura, zwłaszcza w napadach ogniskowych wtórnie uogólnionych. Po napadzie następuje faza ponapadowa, trwająca od kilku minut do godzin, objawiająca się splątaniem, zmęczeniem, bólem głowy, amnezją oraz ewentualnym przejściowym porażeniem Todda. Napady trwające ponad 5 minut lub występujące seryjnie bez odzyskania świadomości definiują stan padaczkowy (status epilepticus), stanowiący zagrożenie życia i wymagający pilnej interwencji.

Drgawki toniczno-kloniczne (drgawki duże) – charakterystyka

Drgawki toniczno-kloniczne, dawniej określane jako napady grand mal (drgawki duże), są jednym z najbardziej dramatycznych i rozpoznawalnych typów napadów padaczkowych. Charakteryzują się gwałtownymi skurczami mięśni i utratą świadomości, będącymi wynikiem nagłego wyładowania nieprawidłowej aktywności elektrycznej w mózgu. W drgawkach toniczno-klonicznych występuje zaburzenie czynności obu półkul mózgowych jednocześnie, co prowadzi do uogólnionych objawów ruchowych i zaburzeń świadomości.123

Napady toniczno-kloniczne mogą rozpoczynać się jako napady ogniskowe w małym obszarze mózgu, a następnie rozprzestrzeniać się i uogólniać, obejmując cały mózg (tzw. napady ogniskowe wtórnie uogólnione), lub mogą od początku obejmować obie półkule mózgowe (napady pierwotnie uogólnione).123

Fazy napadu toniczno-klonicznego

Napad toniczno-kloniczny składa się z dwóch wyraźnych faz, którym może towarzyszyć także faza prodromalna (przednapadowa) oraz faza ponapadowa:123

Prodrom i aura

Przed wystąpieniem właściwego napadu niektórzy pacjenci mogą doświadczać objawów prodromalnych (zwiastunów) na godziny lub nawet dni przed napadem. Objawy te mogą obejmować:123

  • Zmiany nastroju
  • Niepokój lub lęk
  • Uczucie zawrotów głowy
  • Trudności ze snem
  • Problemy z koncentracją
  • Zmiany w zachowaniu

12

Bezpośrednio przed napadem (jako część początkowa napadu) niektórzy pacjenci mogą doświadczać aury, szczególnie w przypadku napadów ogniskowych wtórnie uogólnionych. Aura może obejmować:123

  • Zaburzenia widzenia, smaku, węchu lub czucia
  • Doznania typu déjà vu lub jamais vu
  • Halucynacje (widzenie, czucie lub słyszenie rzeczy, których nie ma)
  • Zawroty głowy
  • Uczucie nudności lub niepokoju
  • Uczucie „wędrującego” w górę żołądka

12

Faza toniczna

Faza toniczna jest pierwszą częścią właściwego napadu i zazwyczaj trwa około 10-20 sekund. Podczas tej fazy:123

  • Pacjent traci przytomność natychmiast
  • Wszystkie mięśnie gwałtownie sztywnieją (toniczny skurcz mięśni)
  • Jeśli pacjent stoi lub siedzi, upada na ziemię
  • Często pojawia się głośny krzyk lub jęk spowodowany przepchnięciem powietrza przez zaciśnięte struny głosowe (nie jest to oznaka bólu)
  • Może wystąpić zgięcie tułowia oraz uniesienie i odwiedzenie łokci, a następnie wyprost pleców, szyi, ramion i nóg
  • Pojawia się bezdech w wyniku skurczu krtani, co może powodować sinicę (sine zabarwienie skóry, szczególnie wokół ust i paznokci)
  • Może dojść do przygryzienia języka lub wewnętrznej części policzka

1234

Faza kloniczna

Bezpośrednio po fazie tonicznej następuje faza kloniczna, która zwykle trwa od 1 do 2 minut, rzadko dłużej. W tej fazie:123

  • Mięśnie wchodzą w fazę rytmicznych skurczów
  • Kończyny (ręce i nogi) silnie drgają i wykonują gwałtowne, rytmiczne ruchy
  • Mięśnie naprzemiennie kurczą się i rozluźniają
  • Drgawki są początkowo intensywne i szybkie, stopniowo stają się wolniejsze
  • Z ust może wydobywać się piana lub ślina, czasem podbarwiona krwią (w wyniku przygryzienia języka lub policzka)
  • Może dojść do utraty kontroli nad pęcherzem i/lub jelitami (nietrzymanie moczu lub stolca)
  • Oddech może być utrudniony lub nieregularny

1234

Typowy napad toniczno-kloniczny trwa łącznie od 1 do 3 minut. Jeśli napad trwa dłużej niż 5 minut lub występuje seria napadów bez odzyskania świadomości pomiędzy nimi, jest to stan padaczkowy (status epilepticus), który wymaga natychmiastowej pomocy medycznej.123

Faza ponapadowa (postictal)

Po ustąpieniu drgawek następuje faza ponapadowa (postictal), która może trwać od kilku minut do kilku godzin, a w rzadkich przypadkach nawet do kilku dni. W tym okresie pacjent:123

  • Powoli odzyskuje świadomość, ale przez kilka minut może pozostawać nieprzytomny
  • Jest zdezorientowany i splątany (tzw. splątanie ponapadowe, postictal confusion)
  • Może odczuwać silne zmęczenie i senność
  • Może mieć trudności z pamięcią (amnezja) dotyczące całego epizodu napadowego
  • Często cierpi na silny ból głowy
  • Może doświadczać bólu i dyskomfortu w mięśniach
  • W niektórych przypadkach może wystąpić przejściowe osłabienie jednej strony ciała (tzw. porażenie Todda lub pareza Todda), trwające od kilku minut do nawet 36 godzin
  • Może wykazywać zmiany nastroju – niepokój, drażliwość, depresję lub zakłopotanie

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Specyficzne objawy i manifestacje kliniczne

Drgawki toniczno-kloniczne charakteryzują się różnorodnymi objawami, które mogą występować w różnym nasileniu. Objawy te można podzielić na kilka kategorii:12

Objawy ruchowe

  • Sztywność mięśni – całkowite usztywnienie ciała, szczególnie kończyn, tułowia, pleców i szyi podczas fazy tonicznej12
  • Drgawki ruchowe – rytmiczne skurcze i rozluźnienia grup mięśniowych, powodujące szarpnięcia i drgania kończyn w fazie klonicznej12
  • Łukowate wygięcie ciała – wyprężenie pleców w łuk podczas fazy tonicznej1
  • Upadek – z powodu nagłej utraty napięcia mięśniowego i świadomości12
  • Zgrzytanie zębami lub zaciśnięcie szczęki – może prowadzić do przygryzienia języka lub policzka1

Objawy autonomiczne

  • Nietrzymanie moczu lub stolca – występuje często podczas drgawek lub bezpośrednio po nich w wyniku rozluźnienia mięśni zwieraczy12
  • Nadmierne ślinienie – często z pianą wokół ust, czasem z domieszką krwi z przygryzionego języka lub policzka1
  • Zaburzenia oddychania – trudności w oddychaniu, bezdech, nieregularny oddech spowodowany skurczem mięśni oddechowych12
  • Sinica – sinawe zabarwienie skóry, szczególnie wokół ust, spowodowane niedotlenieniem12
  • Rozszerzenie źrenic – podczas napadu źrenice mogą się rozszerzać i zwężać1

Objawy świadomościowe

  • Utrata świadomości – natychmiastowa i całkowita, pacjent nie reaguje na bodźce zewnętrzne12
  • Brak pamięci epizodu – pacjent zwykle nie pamięta samego napadu i okoliczności bezpośrednio przed nim12
  • Krzyk lub jęk – często występuje na początku napadu, spowodowany wyparciem powietrza przez skurczone struny głosowe, nie jest wyrazem bólu12

Objawy ponapadowe

  • Splątanie – dezorientacja i zamroczenie po ustąpieniu drgawek12
  • Zmęczenie i senność – często występuje silne zmęczenie po napadzie12
  • Ból głowy – często o dużym nasileniu12
  • Ból mięśni – spowodowany intensywnymi skurczami podczas napadu1
  • Porażenie Todda – przejściowe osłabienie jednej strony ciała, które może utrzymywać się od kilku minut do kilku godzin po napadzie12

Progresja i czas trwania napadu

Typowy napad toniczno-kloniczny ma charakterystyczną progresję i czas trwania poszczególnych faz:123

Sekwencja czasowa napadu

  • Aura (jeśli występuje) – kilka sekund do kilku minut przed właściwym napadem1
  • Faza toniczna – zwykle trwa około 10-20 sekund123
  • Faza kloniczna – zwykle trwa od 30 sekund do 2 minut12
  • Całkowity czas napadu – zazwyczaj między 1 a 3 minuty123
  • Faza ponapadowa – może trwać od kilku minut do kilku godzin, rzadko dni12

Jeśli napad trwa dłużej niż 5 minut lub jeśli osoba doświadcza kolejnego napadu przed powrotem do świadomości po poprzednim, stan ten określa się jako stan padaczkowy (status epilepticus). Jest to stan zagrożenia życia wymagający natychmiastowej pomocy medycznej, ponieważ może prowadzić do trwałego uszkodzenia mózgu lub nawet śmierci.1234

Dynamika objawów w czasie napadu

Napad toniczno-kloniczny ma dynamiczną progresję, z charakterystycznymi objawami pojawiającymi się w określonej sekwencji:123

  1. Początek nagły – zazwyczaj bez ostrzeżenia lub poprzedzony aurą12
  2. Utrata przytomności – następuje błyskawicznie na początku napadu12
  3. Upadek – jeśli pacjent stoi lub siedzi12
  4. Usztywnienie ciałafaza toniczna z wyprostowaniem kończyn12
  5. Krzyk lub jęk – spowodowany przepchnięciem powietrza przez skurczone struny głosowe12
  6. Rytmiczne drgawki – narastające, a następnie słabnące12
  7. Ustąpienie drgawek – stopniowe wygaszanie aktywności drgawkowej1
  8. Rozluźnienie ciała – może towarzyszyć mu nietrzymanie moczu lub stolca12
  9. Stopniowy powrót świadomości – początkowe splątanie i dezorientacja12
  10. Faza ponapadowa – zmęczenie, ból głowy, splątanie12

Warto zauważyć, że choć większość napadów toniczno-klonicznych przebiega według powyższej sekwencji, mogą występować indywidualne różnice w prezentacji objawów. Niektórzy pacjenci mogą doświadczać tylko fazy tonicznej lub tylko fazy klonicznej, podczas gdy inni przechodzą przez pełny cykl toniczno-kloniczny.12

Szczególne aspekty drgawek toniczno-klonicznych

Potencjalne powikłania napadów

Drgawki toniczno-kloniczne mogą prowadzić do różnych powikłań, szczególnie jeśli są nieleczone, częste lub przedłużające się:123

  • Urazy fizyczne – upadki, urazy głowy, złamania kompresyjne kręgosłupa, urazy języka, warg i policzków12
  • Zachłystowe zapalenie płuc – w wyniku aspiracji treści pokarmowej do dróg oddechowych1
  • Neurogenny obrzęk płuc – powikłanie rzadkie, ale poważne1
  • Zaburzenia rytmu serca – mogą wystąpić podczas napadu1
  • Zaburzenia poznawcze – częste napady mogą prowadzić do problemów z pamięcią i funkcjami poznawczymi12
  • Zaburzenia nastroju – depresja, niepokój12
  • Stan padaczkowy – przedłużający się napad (>5 minut) lub seria napadów bez odzyskania świadomości między nimi, co stanowi zagrożenie życia12
  • Nagła nieoczekiwana śmierć w epilepsji (SUDEP) – rzadkie, ale poważne powikłanie, najbardziej narażone są osoby z częstymi napadami toniczno-klonicznymi12

Czynniki wyzwalające napady

Niektóre czynniki mogą zwiększać ryzyko wystąpienia napadu toniczno-klonicznego u osób z padaczką:12

  • Deprywacja snu – niewystarczająca ilość snu lub zaburzenia rytmu snu1
  • Stres – zarówno fizyczny, jak i emocjonalny1
  • Alkohol – szczególnie spożywany w dużych ilościach lub podczas odstawienia po okresie intensywnego picia1
  • Gorączka – podwyższona temperatura ciała1
  • Infekcje – szczególnie te dotyczące ośrodkowego układu nerwowego1
  • Pomijanie dawek leków przeciwpadaczkowych – nieregularne przyjmowanie przepisanych leków1
  • Migające światła – u osób z padaczką fotoczułą1
  • Udar mózgu i urazy głowy – mogą wyzwalać napady prowokowane1
  • Zmiany hormonalne – u niektórych kobiet w związku z cyklem menstruacyjnym1

Znaczenie fazy ponapadowej

Faza ponapadowa (postictal) jest ważnym elementem w przebiegu drgawek toniczno-klonicznych i ma istotne znaczenie diagnostyczne oraz kliniczne:123

  • Czas trwania – faza ponapadowa po drgawkach toniczno-klonicznych jest zazwyczaj dłuższa i bardziej wyrazista niż po innych typach napadów12
  • Różnice indywidualne – czas powrotu do pełnej sprawności może się znacznie różnić między pacjentami, od godziny do nawet kilku dni1
  • Nasilenie objawów – zwykle koreluje z intensywnością i czasem trwania napadu – dłuższe i cięższe napady prowadzą do bardziej nasilonych objawów ponapadowych1
  • Porażenie Todda – ważny objaw diagnostyczny, może przypominać udar, ale ma charakter przejściowy12
  • Wpływ na codzienne funkcjonowanie – objawy ponapadowe mogą znacząco upośledzać zdolność do pracy, nauki i innych codziennych aktywności1

Prognoza i ryzyko nawrotów

Rokowanie w przypadku napadów toniczno-klonicznych zależy od wielu czynników:123

  • Przyczyna napadów – najlepsze rokowanie mają napady o przyczynie możliwej do wyleczenia12
  • Pierwotne lub wtórne – napady występujące w ramach pierwotnie uogólnionej padaczki zwykle dobrze odpowiadają na leki przeciwpadaczkowe1
  • Ryzyko nawrotu – po pierwszym napadzie toniczno-klonicznym ryzyko wystąpienia kolejnego wynosi około 30-50%, według badań obserwacyjnych aż 40-80% osób doświadczy kolejnego napadu123
  • Największe ryzyko nawrotu – występuje w pierwszych miesiącach po początkowym napadzie i zmniejsza się z upływem czasu1
  • Wpływ leczenia – właściwe leczenie przeciwpadaczkowe znacząco zmniejsza ryzyko nawrotów1

W przypadku padaczki z napadami toniczno-klonicznymi występującymi jako jedyny typ napadów (GTCA – Generalized Tonic-Clonic Seizures Alone), rokowanie jest zazwyczaj dobre. Napady często dobrze odpowiadają na leczenie przeciwpadaczkowe, choć pacjenci mogą wymagać przyjmowania leków przez całe życie, ponieważ przerwanie leczenia może prowadzić do nawrotu napadów.1

Charakterystyczne cechy drgawek toniczno-klonicznych

Drgawki toniczno-kloniczne (dawniej grand mal) są najbardziej rozpoznawalnym typem napadów padaczkowych, charakteryzującym się gwałtownymi objawami ruchowymi i utratą świadomości. Ich przebieg obejmuje fazę toniczną z usztywnieniem mięśni (trwającą około 10-20 sekund) oraz fazę kloniczną z rytmicznymi drgawkami (trwającą 1-2 minuty). Całkowity czas napadu wynosi zazwyczaj 1-3 minuty. Po napadzie następuje faza ponapadowa z objawami takimi jak splątanie, zmęczenie, ból głowy i dezorientacja, która może trwać od kilku minut do nawet kilku godzin.1234

Napady drgawkowe trwające dłużej niż 5 minut lub występujące seryjnie bez odzyskania świadomości między nimi stanowią stan padaczkowy wymagający natychmiastowej pomocy medycznej. Właściwe leczenie przeciwpadaczkowe może skutecznie kontrolować napady u większości pacjentów, znacząco poprawiając jakość ich życia.123

Kolejne rozdziały

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  1. 10.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Tonic-clonic (grand mal) seizure – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/grand-mal-seizure/symptoms-causes/syc-20363458
    A tonic-clonic seizure, previously known as a grand mal seizure, causes a loss of consciousness and violent muscle contractions. It’s the type of seizure most people picture when they think about seizures. […] During a seizure, there’s a burst of electrical activity in the brain that causes changes in behavior and movements. […] Tonic-clonic seizures may begin as focal seizures in a small area of the brain and spread to become generalized seizures that involve the whole brain. […] In tonic-clonic seizures, the muscles become stiff, causing the person to fall. Then the muscles alternately flex and relax. […] Tonic-clonic seizures have two stages: Tonic phase. Often, someone in the tonic phase will make a sound, such as a groan or yell. The muscles suddenly get stiff and cause the person to fall down. Loss of consciousness occurs. This phase tends to last about 10 to 20 seconds.
  • #1 Bilateral tonic-clonic seizure: MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/000695.htm
    Bilateral tonic-clonic seizure is a type of seizure that involves the entire body. It is also called grand mal seizure. The terms generalized seizure, convulsion, or epilepsy are most often associated with bilateral tonic-clonic seizures. […] Many people with generalized bilateral tonic-clonic seizures have an aura with one or more symptoms before the seizure such as: Vision, taste, smell, or sensory changes. Seeing, smelling, or sometimes hearing things that are not there (hallucinations). Dizziness or other symptoms. […] The seizures often result in rigid muscles (tonic phase). This is followed by violent muscle contractions (clonic phase). Other symptoms that occur during the seizure may include: Biting the cheek or tongue, Clenched teeth or jaw, Loss of urine or stool control (incontinence), Stopped breathing or difficulty breathing, Blue skin color (cyanosis).
  • #1 Seizure Phases | Epilepsy FoundationFacebookInstagramTwitterPhoneEmailFacebookInstagramTwitter
    https://epilepsyfoundation.org.au/understanding-epilepsy/seizures/seizure-phases/
    The three seizure phases are defined as: […] During the prodromal stage some people can tell when a seizure is on its way. They may notice some early signs hours or even days before the seizure starts. Not all people experience this stage. Some common signs can include: Mood changes, Anxiety, Feeling lightheaded, Difficulty sleeping, Difficulty staying focused, Behaviour changes. […] Auras are generally considered an early part of the seizure. Symptoms of an aura may include: déjà vu (a sense that something has happened before when in fact it hasn’t), Jamais vu (a feeling that you’re seeing something you know well for the first time), Odd smells, sounds or tastes, Dizziness, Vision difficulties, Numbness or ‘pins and needles’ in parts of the body, Nausea, Headache, Panic, Feelings of intense fear.
  • #1 Tonic-clonic (grand mal) seizure – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/grand-mal-seizure/symptoms-causes/syc-20363458
    Clonic phase. The muscles go into rhythmic contractions. The arms and legs often jerk. They alternately flex and relax. Convulsions usually last 1 to 2 minutes or less. […] The following symptoms occur in some but not all people with tonic-clonic seizures: Loss of bowel and bladder function. This may happen during or following a seizure. […] Not responding after convulsions. The person may not become conscious for several minutes after convulsions have ended. […] Confusion. The person often is disoriented after a tonic-clonic seizure. This is referred to as postictal confusion. […] Fatigue. Sleepiness is common after a tonic-clonic seizure. […] Bad headache. Headaches may occur after a tonic-clonic seizure.
  • #1 Tonic-Clonic (Grand Mal) Seizure | Cedars-Sinai
    https://www.cedars-sinai.org/health-library/diseases-and-conditions/t/tonic-clonic-grand-mal-seizure.html
    A tonic-clonic seizure, also called a grand mal seizure, causes violent muscle contractions and loss of consciousness. […] The muscles of the arms and legs stiffen during the first part of the seizure, called the tonic part. Then, the muscles of the arms, legs and face begin to jerk during the second phase of the seizure, known as the clonic part. Some patients may only experience one part of the seizure. Others may experience both. […] Tonic-clonic seizures last between one and three minutes. Any seizure lasting longer than 5 minutes will need medical attention. […] Symptoms of a tonic-clonic seizure may include: Stiff muscles, Loss of consciousness, A cry or groan, Jerking of the arms or legs, Loss of bladder or bowel control, Limited or even stopped breathing, Blue lips, Arched back. […] After the seizure the patient may experience: Confusion, Feeling sleepy or drowsy for 1 hour or longer (post-ictal state), Loss of memory (amnesia) about the seizure episode, Headache, Weakness of one side of the body for a few minutes to a few hours (Todd paralysis).
  • #1 Tonic-Clonic Seizures – Epilepsy Ontario
    https://epilepsyontario.org/about-epilepsy/types-of-seizures/tonic-clonic-seizures/
    The extremities will then jerk and twitch rhythmically (clonic phase). Saliva that has not been swallowed during the seizure may froth at the mouth. Breathing may be irregular as the respiratory muscles may be affected. The person will regain consciousness slowly. […] The period after the seizure is referred to as the post-ictal state. During this time, the person will need to rest. It may be difficult to wake him/her or get any response from him/her during this time. After a seizure, the person may feel fatigue, confusion and disorientation, which may last from five minutes to several hours or even days. Rarely, this disorientation may last up to two weeks. […] The person may fall asleep, or gradually become less confused until full consciousness is regained. S/he may have a headache once s/he regains consciousness. There is no evidence that tonic-clonic seizures cause brain damage.
  • #1 Tonic, clonic and tonic-clonic seizures
    https://www.aboutkidshealth.ca/tonic-clonic-and-tonic-clonic-seizures
    Tonic-clonic seizures involve sudden muscle stiffening and contraction, and rhythmic twitching or jerking. […] They generally last about a minute, but in some cases can last longer. […] They involve a mix of sudden muscle stiffness and rhythmic jerking in a set pattern, as well as other symptoms. […] The first sign of a tonic-clonic seizure is that a child cries out or groans loudly, then falls down. The child may lose consciousness at this point or later in the seizure. […] In the tonic phase of the seizure, the child becomes rigid, their teeth clench, they may stop breathing and turn blue, and saliva (spit) or foam may drip from their mouth. […] In the clonic phase of the seizure, the child’s arms and legs jerk quickly and rhythmically; their pupils contract (become small) and dilate (become big).
  • #1 Bilateral tonic-clonic seizure: MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/000695.htm
    After the seizure, the person may have: Confusion, Drowsiness or sleepiness that lasts for 1 hour or longer (called the post-ictal state), Loss of memory (amnesia) about the seizure episode, Headache, Weakness of one side of the body for a few minutes to a few hours following seizure (called Todd paralysis).
  • #1 Tonic-clonic seizures – Epilepsy Action
    https://www.epilepsy.org.uk/info/seizures/tonic-clonic
    When you wake up, minutes or hours later, you might still have a headache, feel sore and have aching muscles. […] Some people might feel very confused and scared and can act in unusual ways. […] The length of time it takes to recover after a tonic-clonic seizure is different for everyone. […] Some people feel better after an hour or two, but for some people it can take several days to feel back to normal. […] A very small number of people find they have temporary weakness or cant move part of their body after theyve had a seizure. […] This is called Todds Paralysis or Todds paresis. […] It can last from a few minutes up to 36 hours, before going away.
  • #1 Types of Seizures and Their Symptoms
    https://www.webmd.com/epilepsy/types-of-seizures-their-symptoms
    Tonic-clonic seizures may begin with an aura an abnormal sensation or feeling marked by a particular smell, a feeling of vertigo, nausea, or anxiety. They involve a tonic phase and then a clonic phase. When you have this type, you lose consciousness and your body stiffens, and then it jerks and shakes. Sometimes, as the seizure ends and your body relaxes, you lose control of your bladder or bowels. They usually last 1 to 3 minutes; if they go on longer, someone should call 911. Tonic-clonic seizures were originally called grand mal seizures.
  • #1 Generalized Tonic-Clonic Seizure – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK554496/
    A generalized tonic-clonic seizure, formerly known as grand mal seizure, is defined as a seizure that has a tonic phase followed by clonic muscle contractions. Among patients, families, and observers, they are most feared of seizure types. They are usually associated with impaired awareness or complete loss of consciousness. […] Generalized tonic-clonic seizures arise within and rapidly involve bilateral cortical, subcortical, and brainstem networks of the brain. […] Generalized tonic-clonic seizures begin with an abrupt loss of consciousness without any aura. The tonic phase of seizure can start with a scream with a generalized stiffening of the body with or without cyanosis. After the initial tonic phase, clinical features evolve into clonic jerking followed by postictal sleepiness, confusion, or agitation.
  • #1 Seizures – treatments, symptoms, causes and prevention | healthdirect
    https://www.healthdirect.gov.au/seizures
    Seizures can cause changes in movement, sensation, awareness, thought or behaviour, depending on which part of the brain the seizure affects. Some seizures involve only part of the brain, others involve the whole brain. […] Symptoms of seizures include: change of consciousness (awareness) during the seizure, or between seizures; becoming unresponsive; staring into space; becoming vague, disorientated or confused; numbness or tingling sensations; hallucinations (seeing, hearing or feeling things that are not there); problems with thinking. […] Motor (movement) symptoms can include: stiffening movements (known as the 'tonic’ phase) this may cause a person to fall; jerking movements (known as the 'clonic’ phase); switching between stiffening and jerking (known as 'tonic-clonic’); floppiness and loss of muscle tone (known as 'atonic’) this may also cause a person to fall; tremor or shaking or strange postures; sudden nod of the head; repetitive movements, such as lip smacking or chewing.
  • #1 Generalized Tonic-Clonic Seizure – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK554496/
    A postictal state of confusion, somnolence, headache, personality, and mood changes are common and characteristic of generalized tonic-clonic seizures. […] The prognosis for generalized tonic-clonic seizures is dependent on the cause of the seizure and risk factors for the patient. On average, the risk of recurrent seizures is about 40% based on observational studies. The risk of recurrent seizure is highest during the period immediately after the initial seizure and decreases with increasing time from the event. […] Patients with generalized tonic-clonic seizures are at increased risk of psychiatric disorders, cognitive impairment, sleep disorders, cardiovascular disease, bone disease, physical injuries, and even premature mortality. The most significant risk factor for sudden unexpected death in epilepsy (SUDEP) is frequent generalized tonic-clonic seizures.
  • #1 Generalized Tonic-Clonic Seizures: Background, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/1184608-overview
    The morbidity for tonic-clonic seizure can be high because these patients experience no aura and thus the seizure strikes without warning; minor injuries are frequent. […] Potential complications of generalized tonic-clonic seizures include the following: Head trauma and trauma to the tongue, lips, and cheeks, Vertebral compression fractures, Aspiration pneumonia, Neurogenic pulmonary edema, Cardiac arrhythmias, Sudden death. […] Mortality rates for seizures are low, but, amongst the epilepsies, rates for tonic-clonic seizures are higher. The incidence of sudden death is 24 times higher in persons with epilepsy than in the general population.
  • #1 Epilepsy
    https://www.nhs.uk/conditions/epilepsy/
    Symptoms of seizures can include: your body becoming stiff or floppy […] the main types of epileptic seizure are: tonic clonic seizures, where you become unconscious and may fall, your muscles get stiff and your body jerks and shakes […] A seizure usually lasts a few seconds or minutes, and stops by itself. […] Rarely, a seizure can last a long time, or you may have several seizures without recovering in between. This is called status epilepticus, and needs urgent treatment to prevent damage to your brain.
  • #1 Epilepsy with generalised tonic-clonic seizures alone – Epilepsy Action
    https://www.epilepsy.org.uk/info/syndromes/epilepsy-with-generalised-tonic-clonic-seizures-alone
    People with this syndrome only have generalised tonic-clonic seizures. With this type of seizure, the person stiffens (the tonic part), falls unconscious and then makes repeated and rhythmic jerks with their arms or legs (the clonic part). A generalised seizure means both sides of the brain are affected from the start. […] In GTCA, the seizures most often happen in the first 2 hours after waking up. However, they can happen at any time during sleep or when awake. […] Most people with GTCA dont get seizures very often sometimes only once a year. There are certain things that may act as triggers for seizures. These include lack of sleep, feeling stressed, or drinking large amounts of alcohol. […] People with GTCA are very unlikely to have other types of seizures like absence, myoclonic or focal seizures.
  • #1 Seizures – Types, Symptoms and Causes
    https://www.cureepilepsy.org/understanding-epilepsy/epilepsy-basics/what-is-seizure/
    Seizures vary from person to person, depending upon their seizure type. Thats because epilepsy is a spectrum disorder, meaning the causes, type, and severity can differ greatly amongst those affected by it. […] Some common triggers include: […] The signs and symptoms of a seizure will vary from person to person, as well as the type, severity, and phase of the seizure. General signs and symptoms can include: […] Its important to remember that some seizures are visible to others, whereas others are not. Most seizures last between 30 seconds and 2 minutes; if a seizure lasts longer than 5 minutes, you should seek medical care immediately. […] Discover the signs, symptoms, and progression of a seizure.
  • #1 Grand Mal (Tonic-Clonic) Seizure: Causes, Treatment, and More
    https://resources.healthgrades.com/right-care/brain-and-nerves/grand-mal-seizures
    After a tonic-clonic seizure, a person may experience: slowly returning awareness and consciousness, confusion, fatigue and sleepiness, weakness, memory impairment or loss, mood symptoms, such as irritability or depression. […] Not all seizures are medical emergencies, but some are. Call 911 or seek emergency medical treatment for any of the following traits with seizures: The seizure lasts 5 minutes or more. […] Tonic-clonic seizures can happen as provoked seizures. These are not the result of epilepsy but are a symptom of acute illness. Conditions such as infections, stroke, and concussion can provoke tonic-clonic seizures. […] Not everyone who has had a tonic-clonic seizure will have another one in their lifetime. A 2017 study suggests that the likelihood of having another tonic-clonic seizure may be 30–50%. […] Tonic-clonic seizures and epilepsy can sometimes have significant complications, such as impaired quality of life, injury, breathing complications, such as pulmonary aspiration, status epilepticus, brain damage.
  • #1 Seizure Recovery Time, What to Do, and When to Get Help
    https://www.healthline.com/health/epilepsy/seizure-recovery-time
    When many people think of seizures, they think of tonic-clonic seizures that cause unconsciousness and full-body muscle spasms. […] Seizures typically pass in a few seconds to minutes, but they can sometimes cause symptoms like fatigue or headaches that linger for hours to days. […] The recovery period directly after a seizure is medically known as the postictal phase. This period usually lasts between 5-30 minutes and can cause various symptoms, such as cognitive symptoms: confusion, coma, delirium, unresponsiveness, memory problems, perception and cognitive disturbances (psychosis), headache, exhaustion, drowsiness, depression or other mood changes, weakness or paralysis in part or all of your body (Todd paresis), trouble speaking, nausea, visual and auditory changes: hallucinations, visual loss, auditory illusions (palinacousis), autonomic nervous system dysregulation: coughing, spitting, excess salvia production, nose rubbing, fever, heart arrhythmia, heart attack, fluid in the lungs, breathing changes, high blood pressure.
  • #1 Epilepsy with generalised tonic-clonic seizures alone – Epilepsy Action
    https://www.epilepsy.org.uk/info/syndromes/epilepsy-with-generalised-tonic-clonic-seizures-alone
    People with GTCA have a good long-term outlook. Seizures usually respond well to treatment with epilepsy medicines. You or your child may need to keep taking medicines throughout their life, because seizures may start again if the medicine is stopped. Only a few people with GTCA will have mild learning or attention difficulties. Your doctor can advise on support available for this if needed.
  • #2 Tonic-Clonic (Grand Mal) Seizure: Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/22788-tonic-clonic-grand-mal-seizure
    Tonic-clonic seizures, formerly known as grand mal seizures, are the most visible and recognized type of seizure. These involve uncontrolled convulsions and other muscle movements. They usually dont last more than a few minutes, but often happen with epilepsy and sometimes cause severe problems and injuries. […] A tonic-clonic seizure is a type of seizure that causes strong muscle movements on both sides of your body, including convulsions. These are typically the best known and easiest to recognize seizures because of these movements. […] Tonic-clonic seizures are generalized seizures, which means this type of seizure affects both sides of your brain. These seizures make you pass out and affect muscles throughout your body, causing convulsions, shaking and other kinds of uncontrollable muscle movements.
  • #2 Tonic-clonic seizures – Epilepsy Action
    https://www.epilepsy.org.uk/info/seizures/tonic-clonic
    If the seizure starts on one side of the brain and spreads to affect both sides, its called a focal to bilateral tonic-clonic seizure. […] If you have this type of seizure, you might get the symptoms of a focal seizure immediately before you lose consciousness. […] Examples of these symptoms are feeling frightened, having a rising sensation in your stomach or smelling something thats not there. […] Most tonic-clonic seizures last between one and three minutes. […] If a tonic-clonic seizure lasts longer than five minutes, this is called status epilepticus and you may need emergency medical treatment. […] After a tonic-clonic seizure, you might have a headache and feel sore, tired and very unwell. […] You might feel confused, or have memory problems. […] You might go into a deep sleep.
  • #2 Tonic-Clonic (Grand Mal) Seizure: Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/22788-tonic-clonic-grand-mal-seizure
    Tonic-clonic seizures are usually what people think of when they think about seizures and epilepsy. The symptoms are usually more severe and easier to spot and happen in the following phases: […] During this phase, you pass out and muscles throughout your body go rigid (especially your arms and legs), making it look like youre arching your back and lifting your belly upward. […] This phase involves convulsions, which are full-body spasms or shaking. You might also froth at your mouth. […] After a seizure, most people wake up and return to how they felt before the seizure. Its common for you to feel confused, have a headache or feel muscle aches. […] Status epilepticus happens when a seizure lasts for more than five minutes, or another seizure starts before you recover from the first.
  • #2 Generalized Tonic-Clonic Seizures Clinical Presentation: History, Physical Examination, Complications
    https://emedicine.medscape.com/article/1184608-clinical
    Patients with generalized tonic-clonic seizures may report having a prodrome, which comprises premonitory symptoms occurring hours or days before a seizure. Common prodromes include mood changes, sleep disturbances, lightheadedness, anxiety, irritability, difficulty concentrating and, rarely, an ecstatic feeling. […] Patients with generalized tonic-clonic seizures do not have auras. An aura represents a simple partial seizure/focal aware seizure, and a reliable history of aura identifies the seizure as partial and not generalized. […] The patient may have completely nonfocal findings on neurologic examination when not having seizures. Seizures typically are divided into tonic, clonic, and postictal phases, which are described in detail in this section. […] This stage lasts for 10-20 seconds. Generalized convulsive seizures may begin with myoclonic jerks or, rarely, with absences. The tonic phase begins with flexion of the trunk and elevation and abduction of the elbows. Subsequent extension of the back and neck is followed by extension of arms and legs. This can be accompanied by apnea, which is secondary to laryngeal spasm.
  • #2 Types of Seizures and Their Symptoms
    https://www.webmd.com/epilepsy/types-of-seizures-their-symptoms
    Tonic-clonic seizures may begin with an aura an abnormal sensation or feeling marked by a particular smell, a feeling of vertigo, nausea, or anxiety. They involve a tonic phase and then a clonic phase. When you have this type, you lose consciousness and your body stiffens, and then it jerks and shakes. Sometimes, as the seizure ends and your body relaxes, you lose control of your bladder or bowels. They usually last 1 to 3 minutes; if they go on longer, someone should call 911. Tonic-clonic seizures were originally called grand mal seizures.
  • #2 Seizure Phases | Epilepsy FoundationFacebookInstagramTwitterPhoneEmailFacebookInstagramTwitter
    https://epilepsyfoundation.org.au/understanding-epilepsy/seizures/seizure-phases/
    The three seizure phases are defined as: […] During the prodromal stage some people can tell when a seizure is on its way. They may notice some early signs hours or even days before the seizure starts. Not all people experience this stage. Some common signs can include: Mood changes, Anxiety, Feeling lightheaded, Difficulty sleeping, Difficulty staying focused, Behaviour changes. […] Auras are generally considered an early part of the seizure. Symptoms of an aura may include: déjà vu (a sense that something has happened before when in fact it hasn’t), Jamais vu (a feeling that you’re seeing something you know well for the first time), Odd smells, sounds or tastes, Dizziness, Vision difficulties, Numbness or ‘pins and needles’ in parts of the body, Nausea, Headache, Panic, Feelings of intense fear.
  • #2 Tonic-clonic (grand mal) seizure // Middlesex Health
    https://middlesexhealth.org/learning-center/diseases-and-conditions/tonic-clonic-grand-mal-seizure
    A tonic-clonic seizure, previously known as a grand mal seizure, causes a loss of consciousness and violent muscle contractions. […] Tonic-clonic seizures may begin as focal seizures in a small area of the brain and spread to become generalized seizures that involve the whole brain. […] In tonic-clonic seizures, the muscles become stiff, causing the person to fall. Then the muscles alternately flex and relax. […] Tonic-clonic seizures have two stages: Tonic phase. Often, someone in the tonic phase will make a sound, such as a groan or yell. The muscles suddenly get stiff and cause the person to fall down. Loss of consciousness occurs. This phase tends to last about 10 to 20 seconds. […] Clonic phase. The muscles go into rhythmic contractions. The arms and legs often jerk. They alternately flex and relax. Convulsions usually last 1 to 2 minutes or less.
  • #2 Tonic-clonic seizures – Epilepsy Action
    https://www.epilepsy.org.uk/info/seizures/tonic-clonic
    Tonic-clonic seizures can have a generalised onset, meaning they affect both sides of the brain from the start. […] When this happens, the seizure is called a generalised tonic-clonic or bilateral convulsive seizure. […] There are 2 phases in a tonic-clonic seizure: the tonic phase, followed by the clonic phase. […] During the tonic phase: You lose consciousness, so you wont be aware of whats happening. […] All your muscles go stiff, and if youre standing you fall to the floor. […] Air might push past your voice box, which can make a sound like youre crying out. […] You may bite down on your tongue or inside your mouth. […] During the clonic phase: Your limbs jerk quickly and rhythmically. […] You may lose control of your bladder and/or bowels. […] Your breathing may be affected, causing a blue tinge around your mouth.
  • #2 Epilepsy
    https://www.nhs.uk/conditions/epilepsy/
    Symptoms of seizures can include: your body becoming stiff or floppy […] the main types of epileptic seizure are: tonic clonic seizures, where you become unconscious and may fall, your muscles get stiff and your body jerks and shakes […] A seizure usually lasts a few seconds or minutes, and stops by itself. […] Rarely, a seizure can last a long time, or you may have several seizures without recovering in between. This is called status epilepticus, and needs urgent treatment to prevent damage to your brain.
  • #2 Bilateral tonic-clonic seizure: MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/000695.htm
    After the seizure, the person may have: Confusion, Drowsiness or sleepiness that lasts for 1 hour or longer (called the post-ictal state), Loss of memory (amnesia) about the seizure episode, Headache, Weakness of one side of the body for a few minutes to a few hours following seizure (called Todd paralysis).
  • #2 Bilateral tonic-clonic seizure: MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/000695.htm
    Bilateral tonic-clonic seizure is a type of seizure that involves the entire body. It is also called grand mal seizure. The terms generalized seizure, convulsion, or epilepsy are most often associated with bilateral tonic-clonic seizures. […] Many people with generalized bilateral tonic-clonic seizures have an aura with one or more symptoms before the seizure such as: Vision, taste, smell, or sensory changes. Seeing, smelling, or sometimes hearing things that are not there (hallucinations). Dizziness or other symptoms. […] The seizures often result in rigid muscles (tonic phase). This is followed by violent muscle contractions (clonic phase). Other symptoms that occur during the seizure may include: Biting the cheek or tongue, Clenched teeth or jaw, Loss of urine or stool control (incontinence), Stopped breathing or difficulty breathing, Blue skin color (cyanosis).
  • #2 Tonic-Clonic (Grand Mal) Seizure | Cedars-Sinai
    https://www.cedars-sinai.org/health-library/diseases-and-conditions/t/tonic-clonic-grand-mal-seizure.html
    A tonic-clonic seizure, also called a grand mal seizure, causes violent muscle contractions and loss of consciousness. […] The muscles of the arms and legs stiffen during the first part of the seizure, called the tonic part. Then, the muscles of the arms, legs and face begin to jerk during the second phase of the seizure, known as the clonic part. Some patients may only experience one part of the seizure. Others may experience both. […] Tonic-clonic seizures last between one and three minutes. Any seizure lasting longer than 5 minutes will need medical attention. […] Symptoms of a tonic-clonic seizure may include: Stiff muscles, Loss of consciousness, A cry or groan, Jerking of the arms or legs, Loss of bladder or bowel control, Limited or even stopped breathing, Blue lips, Arched back. […] After the seizure the patient may experience: Confusion, Feeling sleepy or drowsy for 1 hour or longer (post-ictal state), Loss of memory (amnesia) about the seizure episode, Headache, Weakness of one side of the body for a few minutes to a few hours (Todd paralysis).
  • #2 Generalized Tonic-Clonic Seizures Clinical Presentation: History, Physical Examination, Complications
    https://emedicine.medscape.com/article/1184608-clinical
    The tonic stage gives way to clonic convulsive movements, in which the tonic muscles relax intermittently for a variable period of time. […] The convulsion, including tonic and clonic phases, lasts around 1-2 minutes. […] The postictal state includes a variable period of decreased consciousness during which the patient becomes quiet and breathing resumes. The patient gradually awakens, often after a period of stupor or sleep, and often is confused, with some automatic behavior. Headache and muscular pain are common. The patient does not recall the seizure itself.
  • #2 Tonic-Clonic Seizures – Epilepsy Ontario
    https://epilepsyontario.org/about-epilepsy/types-of-seizures/tonic-clonic-seizures/
    During a generalized tonic-clonic (formerly grand mal) seizure, electric discharges instantaneously involve the entire brain. The person loses consciousness right from the beginning of the seizure. […] A tonic-clonic seizure usually lasts one to three minutes, but may last up to five minutes. If seizures last more than five minutes, or occur one after another without recovery between seizures, the individual may be experiencing a life-threatening medical emergency and requires immediate medical help. […] The person will usually emit a short, loud cry as the muscles in the chest contract and the air rushes between the vocal cords, making a sound. This cry does not indicate pain. The muscles will stiffen (tonic phase), causing him/her to fall to the floor. Increased pressure on the bladder and bowel may cause wetting (urinary incontinence) or soiling (fecal incontinence). The child may bite the tongue, which may cause bleeding.
  • #2 Tonic-clonic (grand mal) seizure // Middlesex Health
    https://middlesexhealth.org/learning-center/diseases-and-conditions/tonic-clonic-grand-mal-seizure
    The following symptoms occur in some but not all people with tonic-clonic seizures: Loss of bowel and bladder function. This may happen during or following a seizure. […] Not responding after convulsions. The person may not become conscious for several minutes after convulsions have ended. […] Confusion. The person often is disoriented after a tonic-clonic seizure. This is referred to as postictal confusion. […] Fatigue. Sleepiness is common after a tonic-clonic seizure. […] Bad headache. Headaches may occur after a tonic-clonic seizure.
  • #2 Generalized Tonic-Clonic Seizure – UF Health
    https://ufhealth.org/conditions-and-treatments/generalized-tonic-clonic-seizure
    Bilateral tonic-clonic seizure is a type of seizure that involves the entire body. It is also called grand mal seizure. The seizures often result in rigid muscles (tonic phase). This is followed by violent muscle contractions (clonic phase). Other symptoms that occur during the seizure may include: […] Many people with generalized bilateral tonic-clonic seizures have one or more symptoms such as: […] After the seizure, the person may have: […] Weakness of one side of the body for a few minutes to a few hours following seizure (called Todd paralysis).
  • #2 3 Key Tonic-Clonic Seizure Symptoms to Watch | Vejthani
    https://www.vejthani.com/diseases-conditions/tonic-clonic-seizure/
    Clonic phase: This phase often lasts little more than a minute or two. Convulsions, or full-body spasms or shaking, are a characteristic of this phase. You may also froth at the mouth. […] Post-seizure recovery: This may last longer than 30 minutes or longer. Most people wake up from a seizure and feel exactly the same as they did before. You may frequently have headaches, soreness in your muscles, or confusion. […] Some tonic-clonic seizure patients, although not all, have the following signs and symptoms: Confusion: When a tonic-clonic seizure occurs, the patient is frequently confused. Its known as postictal confusion. […] Fatigue: It is typical to feel sleepy following a tonic-clonic seizure. […] Headache: A tonic-clonic seizure may be followed by headaches. […] Loss control of bowel and bladder: This might occur either during or after a seizure. […] Unresponsiveness: Even when the seizures stop, the patient might not wake up for a few minutes.
  • #2 Generalized Seizures (Grand Mal Seizures) – Harvard Health
    https://www.health.harvard.edu/a_to_z/generalized-seizures-grand-mal-seizures-a-to-z
    If the whole brain is involved, the electrical disturbance is called a generalized seizure. This type of seizure used to be called a grand mal seizure. The most easily recognizable symptom of a generalized seizure is the body stiffness and jerking limbs known as tonic-clonic motor activity. […] A seizure begins suddenly. Without warning, the person loses consciousness and experiences the following symptoms: becomes rigid (extends the arms and legs, arches the back) and falls down, utters a cry (the „epileptic cry”) as the diaphragm contracts and forces air out between the contracted vocal cords, has jerking movements of the arms, legs, and trunk muscles, involuntarily passes urine and sometimes feces. […] The seizure usually subsides within two minutes or less, leaving the person confused and sleepy. Over the following 24 hours, he or she may complain of sore muscles, headache, fatigue, and difficulty concentrating.
  • #2 Tonic-Clonic Seizures – Epilepsy Ontario
    https://epilepsyontario.org/about-epilepsy/types-of-seizures/tonic-clonic-seizures/
    The extremities will then jerk and twitch rhythmically (clonic phase). Saliva that has not been swallowed during the seizure may froth at the mouth. Breathing may be irregular as the respiratory muscles may be affected. The person will regain consciousness slowly. […] The period after the seizure is referred to as the post-ictal state. During this time, the person will need to rest. It may be difficult to wake him/her or get any response from him/her during this time. After a seizure, the person may feel fatigue, confusion and disorientation, which may last from five minutes to several hours or even days. Rarely, this disorientation may last up to two weeks. […] The person may fall asleep, or gradually become less confused until full consciousness is regained. S/he may have a headache once s/he regains consciousness. There is no evidence that tonic-clonic seizures cause brain damage.
  • #2 Tonic Clonic Seizures | The Defeating Epilepsy Foundation
    https://www.defeatingepilepsy.org/understanding-epilepsy/tonic-clonic-seizures/
    In this phase, the body experiences twitching or jerking movements of the face, arms, and legs that can occur intensely and rapidly. This phase should diminish within 1-3 minutes and can be seen by the movements slowing down until the body fully relaxes. The relaxation of the body can lead to the loss of bowel or bladder control. […] A tonic-clonic seizure can occur as a generalized seizure affecting both sides of the brain or can arise from a partial seizure that spreads to both hemispheres of the brain from abnormally synchronized electrical activity. The first phase, referred to as the tonic phase, stiffens muscles in the body resulting in the possibility of falling and losing consciousness. The second phase is the clonic phase which affects the face, arms, and legs by causing them to twitch or having intense jerking movements; should start diminishing within 1-3 minutes. If the seizure lasts more than 5 minutes or there are repetitive seizures, call 911. It is also important to provide reassurance to the person experiencing the seizure comes back to consciousness and to remain calm and supportive as they could be disorientated and embarrassed.
  • #2 Generalized Tonic-Clonic Seizures – Sacramento City Unified School District
    https://www.scusd.edu/etraining/generalized-tonic-clonic-seizures
    Can have one symptom Tonic or Clonic, or a mixture of both Tonic-Clonic […] Tonic seizures cause stiffening of muscles of the body, generally those in the back, legs, and arms. Clonic seizures cause repeated jerking movements of muscles on both sides of the body. Tonic-clonic seizures cause a mixture of symptoms, including stiffening of the body and repeated jerks of the arms and/or legs as well as loss of consciousness. Tonic-clonic seizures are sometimes referred to by an older term: grand mal seizures. […] A person having a generalized tonic-clonic seizure: […] may cry out […] Loss of consciousness […] fall to the ground […] rigidity and muscle jerks lasting up to a few minutes […] extended period of confusion and fatigue afterward.
  • #2 Grand mal (tonic-clonic) seizures: Causes, symptoms, and more
    https://www.medicalnewstoday.com/articles/grand-mal-seizure
    After the seizure, there is usually a post-ictal phase. The person will regain consciousness. However, they may fall asleep or remain unconscious for a period. Most people cannot remember the episode and feel groggy and confused for a few hours. […] People often have temporary forgetfulness, trouble with speech, or difficulty moving after a seizure. It is also more common for a person to fall and hurt themselves or bite their tongue when having a tonic-clonic seizure than during other types of seizures. […] Yes, it is possible to die from a tonic-clonic seizure. For example, some people may seriously injure themselves while having a seizure or drown if they have a seizure in water. It is also possible for someone to die from sudden unexpected death in epilepsy (SUDEP). According to the CDC, this happens in about 1 in every 1,000 people with the condition.
  • #2 Do Grand Mal Seizures Cause Brain Damage? | Dr. Gurneet Singh Sawhney
    https://drgurneetsawhney.com/blog/do-grand-mal-seizures-cause-brain-damage/
    Not every grand mal seizure results in brain damage. However, several scenarios can increase the risk: Status epilepticus (a seizure lasting more than 5 minutes) is a neurological emergency that may cause permanent brain damage if untreated. […] Recurrent seizures over time may lead to structural and functional brain changes, especially in individuals with uncontrolled epilepsy. […] Some variables determine whether a grand mal seizure will cause brain injury: Duration: Seizures that are longer put you at higher risk. Frequency: Ongoing seizures without medication can damage the brain in total. […] Repeated or severe grand mal seizures can lead to: Memory issues, Cognitive decline, Mood disorders such as depression or anxiety, Speech and motor impairments, Structural brain changes, particularly in the hippocampus. […] They can especially when left untreated or when episodes are frequent or prolonged. However, with the proper medical care, including medication or surgical options, brain damage can often be prevented or minimized.
  • #2 Grand Mal (Tonic-Clonic) Seizure: Causes, Treatment, and More
    https://resources.healthgrades.com/right-care/brain-and-nerves/grand-mal-seizures
    After a tonic-clonic seizure, a person may experience: slowly returning awareness and consciousness, confusion, fatigue and sleepiness, weakness, memory impairment or loss, mood symptoms, such as irritability or depression. […] Not all seizures are medical emergencies, but some are. Call 911 or seek emergency medical treatment for any of the following traits with seizures: The seizure lasts 5 minutes or more. […] Tonic-clonic seizures can happen as provoked seizures. These are not the result of epilepsy but are a symptom of acute illness. Conditions such as infections, stroke, and concussion can provoke tonic-clonic seizures. […] Not everyone who has had a tonic-clonic seizure will have another one in their lifetime. A 2017 study suggests that the likelihood of having another tonic-clonic seizure may be 30–50%. […] Tonic-clonic seizures and epilepsy can sometimes have significant complications, such as impaired quality of life, injury, breathing complications, such as pulmonary aspiration, status epilepticus, brain damage.
  • #2 Generalized Tonic-Clonic Seizure – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK554496/
    A postictal state of confusion, somnolence, headache, personality, and mood changes are common and characteristic of generalized tonic-clonic seizures. […] The prognosis for generalized tonic-clonic seizures is dependent on the cause of the seizure and risk factors for the patient. On average, the risk of recurrent seizures is about 40% based on observational studies. The risk of recurrent seizure is highest during the period immediately after the initial seizure and decreases with increasing time from the event. […] Patients with generalized tonic-clonic seizures are at increased risk of psychiatric disorders, cognitive impairment, sleep disorders, cardiovascular disease, bone disease, physical injuries, and even premature mortality. The most significant risk factor for sudden unexpected death in epilepsy (SUDEP) is frequent generalized tonic-clonic seizures.
  • #2 Seizure Recovery Time, What to Do, and When to Get Help
    https://www.healthline.com/health/epilepsy/seizure-recovery-time
    Postictal symptoms of focal seizures with impaired awareness may resolve in 1-2 hours. Some symptoms like paralysis or weakness can take 1-2 days to fully resolve. Plus, some people may notice changes in their thinking, mood, and energy levels for days. […] Seizures can cause lingering symptoms that last less than an hour to days. You may develop various symptoms after a seizure is over, such as headache, fatigue, or mood changes.
  • #2 Tonic-clonic seizures – Epilepsy Action
    https://www.epilepsy.org.uk/info/seizures/tonic-clonic
    When you wake up, minutes or hours later, you might still have a headache, feel sore and have aching muscles. […] Some people might feel very confused and scared and can act in unusual ways. […] The length of time it takes to recover after a tonic-clonic seizure is different for everyone. […] Some people feel better after an hour or two, but for some people it can take several days to feel back to normal. […] A very small number of people find they have temporary weakness or cant move part of their body after theyve had a seizure. […] This is called Todds Paralysis or Todds paresis. […] It can last from a few minutes up to 36 hours, before going away.
  • #2 Epilepsy with generalised tonic-clonic seizures alone – Epilepsy Action
    https://www.epilepsy.org.uk/info/syndromes/epilepsy-with-generalised-tonic-clonic-seizures-alone
    People with GTCA have a good long-term outlook. Seizures usually respond well to treatment with epilepsy medicines. You or your child may need to keep taking medicines throughout their life, because seizures may start again if the medicine is stopped. Only a few people with GTCA will have mild learning or attention difficulties. Your doctor can advise on support available for this if needed.
  • #2 Tonic-Clonic (Grand Mal) Seizure: Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/22788-tonic-clonic-grand-mal-seizure
    IMPORTANT NOTE: If youre with someone who has a seizure that lasts more than five minutes or has a second seizure without enough time to recover from the first, you need to call 911 (or your local emergency services number) immediately. […] Conditions and circumstances that can lead to tonic-clonic seizures include: […] A seizure is a malfunction in how your brain cells (neurons) send and relay electrical signals. […] Auras can involve the following symptoms: […] The possible treatments related to seizures also depend on what caused the seizure in the first place. […] Tonic-clonic seizures usually stop on their own, and theres no reason to treat them directly while theyre happening. […] The prognosis is usually better if the condition is treatable and you quickly get treatment. […] The outlook for unprovoked seizures depends on several factors. These include the underlying condition, the severity of your seizures, how often you have them and whether or not treatments help.
  • #3 Tonic-Clonic (Grand Mal) Seizure | Cedars-Sinai
    https://www.cedars-sinai.org/health-library/diseases-and-conditions/t/tonic-clonic-grand-mal-seizure.html
    A tonic-clonic seizure, also called a grand mal seizure, causes violent muscle contractions and loss of consciousness. […] The muscles of the arms and legs stiffen during the first part of the seizure, called the tonic part. Then, the muscles of the arms, legs and face begin to jerk during the second phase of the seizure, known as the clonic part. Some patients may only experience one part of the seizure. Others may experience both. […] Tonic-clonic seizures last between one and three minutes. Any seizure lasting longer than 5 minutes will need medical attention. […] Symptoms of a tonic-clonic seizure may include: Stiff muscles, Loss of consciousness, A cry or groan, Jerking of the arms or legs, Loss of bladder or bowel control, Limited or even stopped breathing, Blue lips, Arched back. […] After the seizure the patient may experience: Confusion, Feeling sleepy or drowsy for 1 hour or longer (post-ictal state), Loss of memory (amnesia) about the seizure episode, Headache, Weakness of one side of the body for a few minutes to a few hours (Todd paralysis).
  • #3 Generalized Tonic-Clonic Seizure – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK554496/
    A generalized tonic-clonic seizure, formerly known as grand mal seizure, is defined as a seizure that has a tonic phase followed by clonic muscle contractions. Among patients, families, and observers, they are most feared of seizure types. They are usually associated with impaired awareness or complete loss of consciousness. […] Generalized tonic-clonic seizures arise within and rapidly involve bilateral cortical, subcortical, and brainstem networks of the brain. […] Generalized tonic-clonic seizures begin with an abrupt loss of consciousness without any aura. The tonic phase of seizure can start with a scream with a generalized stiffening of the body with or without cyanosis. After the initial tonic phase, clinical features evolve into clonic jerking followed by postictal sleepiness, confusion, or agitation.
  • #3 Tonic-clonic (grand mal) seizure // Middlesex Health
    https://middlesexhealth.org/learning-center/diseases-and-conditions/tonic-clonic-grand-mal-seizure
    A tonic-clonic seizure, previously known as a grand mal seizure, causes a loss of consciousness and violent muscle contractions. […] Tonic-clonic seizures may begin as focal seizures in a small area of the brain and spread to become generalized seizures that involve the whole brain. […] In tonic-clonic seizures, the muscles become stiff, causing the person to fall. Then the muscles alternately flex and relax. […] Tonic-clonic seizures have two stages: Tonic phase. Often, someone in the tonic phase will make a sound, such as a groan or yell. The muscles suddenly get stiff and cause the person to fall down. Loss of consciousness occurs. This phase tends to last about 10 to 20 seconds. […] Clonic phase. The muscles go into rhythmic contractions. The arms and legs often jerk. They alternately flex and relax. Convulsions usually last 1 to 2 minutes or less.
  • #3 Seizure Phases | Epilepsy FoundationFacebookInstagramTwitterPhoneEmailFacebookInstagramTwitter
    https://epilepsyfoundation.org.au/understanding-epilepsy/seizures/seizure-phases/
    The three seizure phases are defined as: […] During the prodromal stage some people can tell when a seizure is on its way. They may notice some early signs hours or even days before the seizure starts. Not all people experience this stage. Some common signs can include: Mood changes, Anxiety, Feeling lightheaded, Difficulty sleeping, Difficulty staying focused, Behaviour changes. […] Auras are generally considered an early part of the seizure. Symptoms of an aura may include: déjà vu (a sense that something has happened before when in fact it hasn’t), Jamais vu (a feeling that you’re seeing something you know well for the first time), Odd smells, sounds or tastes, Dizziness, Vision difficulties, Numbness or ‘pins and needles’ in parts of the body, Nausea, Headache, Panic, Feelings of intense fear.
  • #3 Tonic-clonic seizures – Epilepsy Action
    https://www.epilepsy.org.uk/info/seizures/tonic-clonic
    Tonic-clonic seizures can have a generalised onset, meaning they affect both sides of the brain from the start. […] When this happens, the seizure is called a generalised tonic-clonic or bilateral convulsive seizure. […] There are 2 phases in a tonic-clonic seizure: the tonic phase, followed by the clonic phase. […] During the tonic phase: You lose consciousness, so you wont be aware of whats happening. […] All your muscles go stiff, and if youre standing you fall to the floor. […] Air might push past your voice box, which can make a sound like youre crying out. […] You may bite down on your tongue or inside your mouth. […] During the clonic phase: Your limbs jerk quickly and rhythmically. […] You may lose control of your bladder and/or bowels. […] Your breathing may be affected, causing a blue tinge around your mouth.
  • #3 3 Key Tonic-Clonic Seizure Symptoms to Watch | Vejthani
    https://www.vejthani.com/diseases-conditions/tonic-clonic-seizure/
    A tonic-clonic seizure, previously called a grand mal seizure, is a dramatic event characterized by a sudden loss of consciousness and intense muscle contractions. This type of seizure typically begins with a burst of electrical activity in one area of the brain, either as a focal onset that can spread and generalize throughout the brain, affecting behavior and movement globally. During the tonic phase, muscles throughout the body tense up, causing the individual to fall if standing, followed by the clonic phase where muscles begin to contract and relax rhythmically. […] The initial tonic phase results in the stiffening of limbs, while the subsequent clonic phase leads to convulsive movements. These seizures are easily identifiable due to these pronounced physical symptoms. […] The following phases are when the symptoms occur, and they are often more severe and noticeable: Tonic phase: This phase usually lasts between 10 and 20 seconds. You may pass out and all of your muscles, particularly your arms and legs, stiffen up, giving the impression that you are raising your tummy and arching your back.
  • #3 Bilateral tonic-clonic seizure: MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/000695.htm
    Bilateral tonic-clonic seizure is a type of seizure that involves the entire body. It is also called grand mal seizure. The terms generalized seizure, convulsion, or epilepsy are most often associated with bilateral tonic-clonic seizures. […] Many people with generalized bilateral tonic-clonic seizures have an aura with one or more symptoms before the seizure such as: Vision, taste, smell, or sensory changes. Seeing, smelling, or sometimes hearing things that are not there (hallucinations). Dizziness or other symptoms. […] The seizures often result in rigid muscles (tonic phase). This is followed by violent muscle contractions (clonic phase). Other symptoms that occur during the seizure may include: Biting the cheek or tongue, Clenched teeth or jaw, Loss of urine or stool control (incontinence), Stopped breathing or difficulty breathing, Blue skin color (cyanosis).
  • #3 Phases of Seizures – What happens during a Seizure
    https://www.cureepilepsy.org/understanding-epilepsy/epilepsy-basics/phases-of-seizures/
    Seizure signs and symptoms can vary widely depending on the individual, as well as the type, severity, and stage of the seizure. Some seizures are noticeable to others, while some are not. Typically, seizures last between 30 seconds and 2 minutes. However, if a seizure lasts more than 5 minutes, seeking medical attention is crucial.
  • #3 Tonic-clonic seizures – Epilepsy Action
    https://www.epilepsy.org.uk/info/seizures/tonic-clonic
    If the seizure starts on one side of the brain and spreads to affect both sides, its called a focal to bilateral tonic-clonic seizure. […] If you have this type of seizure, you might get the symptoms of a focal seizure immediately before you lose consciousness. […] Examples of these symptoms are feeling frightened, having a rising sensation in your stomach or smelling something thats not there. […] Most tonic-clonic seizures last between one and three minutes. […] If a tonic-clonic seizure lasts longer than five minutes, this is called status epilepticus and you may need emergency medical treatment. […] After a tonic-clonic seizure, you might have a headache and feel sore, tired and very unwell. […] You might feel confused, or have memory problems. […] You might go into a deep sleep.
  • #3 Tonic-clonic seizures – Epilepsy Action
    https://www.epilepsy.org.uk/info/seizures/tonic-clonic
    When you wake up, minutes or hours later, you might still have a headache, feel sore and have aching muscles. […] Some people might feel very confused and scared and can act in unusual ways. […] The length of time it takes to recover after a tonic-clonic seizure is different for everyone. […] Some people feel better after an hour or two, but for some people it can take several days to feel back to normal. […] A very small number of people find they have temporary weakness or cant move part of their body after theyve had a seizure. […] This is called Todds Paralysis or Todds paresis. […] It can last from a few minutes up to 36 hours, before going away.
  • #3 Tonic-Clonic Seizure: Symptoms, What to Do, and More
    https://www.healthline.com/health/generalized-tonic-clonic-seizure
    Clonic activity can cause jerking movements of the arms and legs (convulsions), facial muscle contractions, and loss of bladder or bowel control during or after the seizure. […] After a tonic-clonic seizure, you might fall asleep and wake up feeling confused or sleepy. […] Tonic-clonic seizures usually last 1 to 3 minutes, according to the Epilepsy Foundation.
  • #3 Tonic-Clonic (Grand Mal) Seizure: Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/22788-tonic-clonic-grand-mal-seizure
    Tonic-clonic seizures are usually what people think of when they think about seizures and epilepsy. The symptoms are usually more severe and easier to spot and happen in the following phases: […] During this phase, you pass out and muscles throughout your body go rigid (especially your arms and legs), making it look like youre arching your back and lifting your belly upward. […] This phase involves convulsions, which are full-body spasms or shaking. You might also froth at your mouth. […] After a seizure, most people wake up and return to how they felt before the seizure. Its common for you to feel confused, have a headache or feel muscle aches. […] Status epilepticus happens when a seizure lasts for more than five minutes, or another seizure starts before you recover from the first.
  • #3 Generalized Tonic-Clonic Seizures Clinical Presentation: History, Physical Examination, Complications
    https://emedicine.medscape.com/article/1184608-clinical
    Patients with generalized tonic-clonic seizures may report having a prodrome, which comprises premonitory symptoms occurring hours or days before a seizure. Common prodromes include mood changes, sleep disturbances, lightheadedness, anxiety, irritability, difficulty concentrating and, rarely, an ecstatic feeling. […] Patients with generalized tonic-clonic seizures do not have auras. An aura represents a simple partial seizure/focal aware seizure, and a reliable history of aura identifies the seizure as partial and not generalized. […] The patient may have completely nonfocal findings on neurologic examination when not having seizures. Seizures typically are divided into tonic, clonic, and postictal phases, which are described in detail in this section. […] This stage lasts for 10-20 seconds. Generalized convulsive seizures may begin with myoclonic jerks or, rarely, with absences. The tonic phase begins with flexion of the trunk and elevation and abduction of the elbows. Subsequent extension of the back and neck is followed by extension of arms and legs. This can be accompanied by apnea, which is secondary to laryngeal spasm.
  • #3 Generalized Tonic-Clonic Seizures: Background, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/1184608-overview
    The morbidity for tonic-clonic seizure can be high because these patients experience no aura and thus the seizure strikes without warning; minor injuries are frequent. […] Potential complications of generalized tonic-clonic seizures include the following: Head trauma and trauma to the tongue, lips, and cheeks, Vertebral compression fractures, Aspiration pneumonia, Neurogenic pulmonary edema, Cardiac arrhythmias, Sudden death. […] Mortality rates for seizures are low, but, amongst the epilepsies, rates for tonic-clonic seizures are higher. The incidence of sudden death is 24 times higher in persons with epilepsy than in the general population.
  • #3 Seizure Recovery Time, What to Do, and When to Get Help
    https://www.healthline.com/health/epilepsy/seizure-recovery-time
    When many people think of seizures, they think of tonic-clonic seizures that cause unconsciousness and full-body muscle spasms. […] Seizures typically pass in a few seconds to minutes, but they can sometimes cause symptoms like fatigue or headaches that linger for hours to days. […] The recovery period directly after a seizure is medically known as the postictal phase. This period usually lasts between 5-30 minutes and can cause various symptoms, such as cognitive symptoms: confusion, coma, delirium, unresponsiveness, memory problems, perception and cognitive disturbances (psychosis), headache, exhaustion, drowsiness, depression or other mood changes, weakness or paralysis in part or all of your body (Todd paresis), trouble speaking, nausea, visual and auditory changes: hallucinations, visual loss, auditory illusions (palinacousis), autonomic nervous system dysregulation: coughing, spitting, excess salvia production, nose rubbing, fever, heart arrhythmia, heart attack, fluid in the lungs, breathing changes, high blood pressure.
  • #3 Grand Mal (Tonic-Clonic) Seizure: Causes, Treatment, and More
    https://resources.healthgrades.com/right-care/brain-and-nerves/grand-mal-seizures
    After a tonic-clonic seizure, a person may experience: slowly returning awareness and consciousness, confusion, fatigue and sleepiness, weakness, memory impairment or loss, mood symptoms, such as irritability or depression. […] Not all seizures are medical emergencies, but some are. Call 911 or seek emergency medical treatment for any of the following traits with seizures: The seizure lasts 5 minutes or more. […] Tonic-clonic seizures can happen as provoked seizures. These are not the result of epilepsy but are a symptom of acute illness. Conditions such as infections, stroke, and concussion can provoke tonic-clonic seizures. […] Not everyone who has had a tonic-clonic seizure will have another one in their lifetime. A 2017 study suggests that the likelihood of having another tonic-clonic seizure may be 30–50%. […] Tonic-clonic seizures and epilepsy can sometimes have significant complications, such as impaired quality of life, injury, breathing complications, such as pulmonary aspiration, status epilepticus, brain damage.
  • #3 Seizure disorders: Part 1. Classification and diagnosis
    https://pmc.ncbi.nlm.nih.gov/articles/PMC1071497/
    Tonic-clonic (grand-mal) seizures occur in 25% of all patients with seizures and are the most common type of generalized seizure in adults. […] Tonic-clonic seizures may produce labored respirations, cyanosis, incontinence, involuntary tongue biting (sensitive but not specific sign), and postictal confusion, fatigue, or stupor. […] In untreated patients, recurrence after a first seizure occurs in 64% at 6 months, 70% at 1 year, and 81% at 3 years. […] Tonic-clonic seizures have a recurrence rate of 53% at 6 months, 60% at 1 year, and 72% at 3 years.
  • #3 Tonic-Clonic (Grand Mal) Seizure: Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/22788-tonic-clonic-grand-mal-seizure
    IMPORTANT NOTE: If youre with someone who has a seizure that lasts more than five minutes or has a second seizure without enough time to recover from the first, you need to call 911 (or your local emergency services number) immediately. […] Conditions and circumstances that can lead to tonic-clonic seizures include: […] A seizure is a malfunction in how your brain cells (neurons) send and relay electrical signals. […] Auras can involve the following symptoms: […] The possible treatments related to seizures also depend on what caused the seizure in the first place. […] Tonic-clonic seizures usually stop on their own, and theres no reason to treat them directly while theyre happening. […] The prognosis is usually better if the condition is treatable and you quickly get treatment. […] The outlook for unprovoked seizures depends on several factors. These include the underlying condition, the severity of your seizures, how often you have them and whether or not treatments help.
  • #4 Generalized Tonic-Clonic Seizures Clinical Presentation: History, Physical Examination, Complications
    https://emedicine.medscape.com/article/1184608-clinical
    Patients with generalized tonic-clonic seizures may report having a prodrome, which comprises premonitory symptoms occurring hours or days before a seizure. Common prodromes include mood changes, sleep disturbances, lightheadedness, anxiety, irritability, difficulty concentrating and, rarely, an ecstatic feeling. […] Patients with generalized tonic-clonic seizures do not have auras. An aura represents a simple partial seizure/focal aware seizure, and a reliable history of aura identifies the seizure as partial and not generalized. […] The patient may have completely nonfocal findings on neurologic examination when not having seizures. Seizures typically are divided into tonic, clonic, and postictal phases, which are described in detail in this section. […] This stage lasts for 10-20 seconds. Generalized convulsive seizures may begin with myoclonic jerks or, rarely, with absences. The tonic phase begins with flexion of the trunk and elevation and abduction of the elbows. Subsequent extension of the back and neck is followed by extension of arms and legs. This can be accompanied by apnea, which is secondary to laryngeal spasm.
  • #4 Grand mal (tonic-clonic) seizures: Causes, symptoms, and more
    https://www.medicalnewstoday.com/articles/grand-mal-seizure
    A generalized tonic-clonic seizure makes a persons whole body twitch, jerk, and become unconscious. Grand mal seizure is an older term for this. […] During a generalized tonic-clonic seizure, a person experiences rapid involuntary alternating jerking and stiffening of the body. This can involve the torso, arms, and legs on both sides of the body. The person is unaware of their surroundings and become unresponsive, sometimes losing consciousness. […] Tonic-clonic seizures can last just a few seconds or up to several minutes. Prior to a seizure, a person may experience a visual aura, a change in mood, strange tastes or smells, or headaches. […] During the initial tonic stage, a person may: lose consciousness, fall if standing or sitting upright, experience muscle stiffness. […] The clonic stage will immediately follow the tonic stage. During the clonic stage, a person may experience: jerky movements in large muscle groups, foaming at the mouth or biting the tongue, blue skin or lips, loss of bowel or bladder control, involuntarily shouting or crying out.
  • #4 Generalized Tonic-Clonic Seizure – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK554496/
    A postictal state of confusion, somnolence, headache, personality, and mood changes are common and characteristic of generalized tonic-clonic seizures. […] The prognosis for generalized tonic-clonic seizures is dependent on the cause of the seizure and risk factors for the patient. On average, the risk of recurrent seizures is about 40% based on observational studies. The risk of recurrent seizure is highest during the period immediately after the initial seizure and decreases with increasing time from the event. […] Patients with generalized tonic-clonic seizures are at increased risk of psychiatric disorders, cognitive impairment, sleep disorders, cardiovascular disease, bone disease, physical injuries, and even premature mortality. The most significant risk factor for sudden unexpected death in epilepsy (SUDEP) is frequent generalized tonic-clonic seizures.
  • #4 Managing seizures | Cornell University College of Veterinary Medicine
    https://www.vet.cornell.edu/departments-centers-and-institutes/riney-canine-health-center/canine-health-information/managing-seizures
    The big, bad grand mal seizure is a generalized, convulsive seizure with widespread, excessive, abnormal electrical activity occurring in both sides of the brain. Also known as tonic-clonic, this type of seizure is the one where a dog suddenly falls over with violent, jerking spasms affecting all four limbs, paddling, frothing at the mouth, possible loss of bladder and bowel control, and loss of consciousness. […] Status epilepticus is an ongoing seizure that doesnt self-resolve, typically considered more than five minutes, says Dr. Peter Early, visiting clinical professor of neurology in the Department of Clinical Sciences. […] If a dog is in status epilepticus for too long, they could die. There is so much intense, violent physical activity that the core body temperature rises to life-threatening levels. […] Beyond the classic grand mal seizure described above, other generalized seizures include: Tonic (stiff, extended limbs that dont move or jerk), Clonic (hyper-flexed, non-jerking limbs), Myoclonic (jerking limbs), Atonic (standing, staring and non-responsive).
  • #4 Tonic-clonic (grand mal) seizure // Middlesex Health
    https://middlesexhealth.org/learning-center/diseases-and-conditions/tonic-clonic-grand-mal-seizure
    A tonic-clonic seizure, previously known as a grand mal seizure, causes a loss of consciousness and violent muscle contractions. […] Tonic-clonic seizures may begin as focal seizures in a small area of the brain and spread to become generalized seizures that involve the whole brain. […] In tonic-clonic seizures, the muscles become stiff, causing the person to fall. Then the muscles alternately flex and relax. […] Tonic-clonic seizures have two stages: Tonic phase. Often, someone in the tonic phase will make a sound, such as a groan or yell. The muscles suddenly get stiff and cause the person to fall down. Loss of consciousness occurs. This phase tends to last about 10 to 20 seconds. […] Clonic phase. The muscles go into rhythmic contractions. The arms and legs often jerk. They alternately flex and relax. Convulsions usually last 1 to 2 minutes or less.
  • #5 Seizure Recovery Time, What to Do, and When to Get Help
    https://www.healthline.com/health/epilepsy/seizure-recovery-time
    When many people think of seizures, they think of tonic-clonic seizures that cause unconsciousness and full-body muscle spasms. […] Seizures typically pass in a few seconds to minutes, but they can sometimes cause symptoms like fatigue or headaches that linger for hours to days. […] The recovery period directly after a seizure is medically known as the postictal phase. This period usually lasts between 5-30 minutes and can cause various symptoms, such as cognitive symptoms: confusion, coma, delirium, unresponsiveness, memory problems, perception and cognitive disturbances (psychosis), headache, exhaustion, drowsiness, depression or other mood changes, weakness or paralysis in part or all of your body (Todd paresis), trouble speaking, nausea, visual and auditory changes: hallucinations, visual loss, auditory illusions (palinacousis), autonomic nervous system dysregulation: coughing, spitting, excess salvia production, nose rubbing, fever, heart arrhythmia, heart attack, fluid in the lungs, breathing changes, high blood pressure.