Choroba tętnic szyjnych
Leczenie

Choroba tętnic szyjnych charakteryzuje się zwężeniem naczyń spowodowanym miażdżycą, co zwiększa ryzyko udaru mózgu. Leczenie zachowawcze (Best Medical Treatment, BMT) obejmuje modyfikację stylu życia oraz farmakoterapię, w tym leki przeciwpłytkowe (np. ASA 30-1350 mg/dzień, klopidogrel 75 mg/dzień), statyny obniżające LDL poniżej 70 mg/dl oraz kontrolę ciśnienia tętniczego. W przypadku zwężenia <50% u pacjentów bezobjawowych stosuje się wyłącznie leczenie zachowawcze. Natomiast przy zwężeniu ≥70% lub u pacjentów z objawami neurologicznymi (TIA, udar) wskazane jest leczenie inwazyjne, które obejmuje endarterektomię tętnicy szyjnej (CEA), stentowanie (CAS) lub TCAR, z uwzględnieniem ryzyka okołooperacyjnego i indywidualnych czynników pacjenta.

Choroba tętnic szyjnych – leczenie

Choroba tętnic szyjnych (zwężenie tętnic szyjnych) jest stanem, w którym dochodzi do zwężenia tętnic szyjnych na skutek nagromadzenia blaszki miażdżycowej. Głównym celem leczenia tej choroby jest zapobieganie udarowi mózgu. Wybór odpowiedniej metody terapeutycznej zależy od stopnia zwężenia tętnic, obecności objawów neurologicznych, wieku pacjenta oraz współistniejących chorób12.

Leczenie zachowawcze

W przypadku łagodnego do umiarkowanego zwężenia tętnic szyjnych (poniżej 50%) leczenie zazwyczaj koncentruje się na modyfikacji stylu życia i farmakoterapii12:

Warto podkreślić, że wdrożenie najlepszego leczenia zachowawczego (ang. Best Medical Treatment, BMT) jest podstawowym podejściem w prowadzeniu pacjentów zarówno z objawowym, jak i bezobjawowym zwężeniem tętnic szyjnych12.

Leczenie inwazyjne

W przypadku znacznego zwężenia tętnic szyjnych (powyżej 70%) lub u pacjentów, którzy doświadczyli przejściowego ataku niedokrwiennego (TIA) bądź udaru mózgu, zalecane jest leczenie inwazyjne12. Dostępne są następujące metody operacyjne:

Endarterektomia tętnicy szyjnej (CEA)

Jest to najczęściej wykonywana procedura w przypadku ciężkiego zwężenia tętnicy szyjnej1. Zabieg polega na wykonaniu nacięcia wzdłuż przedniej powierzchni szyi, otwarciu zwężonej tętnicy szyjnej i usunięciu blaszek miażdżycowych. Następnie tętnica jest zszywana lub zamykana za pomocą łaty12.

Endarterektomia tętnicy szyjnej jest skuteczna w zapobieganiu incydentom niedokrwiennym po tej samej stronie u pacjentów z objawową chorobą tętnicy szyjnej, pod warunkiem że łączne ryzyko okołooperacyjne udaru i zgonu nie przekracza 6%12.

Powikłania związane z endarterektomią tętnicy szyjnej obejmują uszkodzenie nerwów czaszkowych (2-7% przypadków, najczęściej dotyczące nerwu krtaniowego wstecznego i podjęzykowego) oraz udar pooperacyjny (1-5% pacjentów)1.

Angioplastyka i stentowanie tętnicy szyjnej (CAS)

Jest to procedura mniej inwazyjna niż endarterektomia tętnicy szyjnej, zalecana dla pacjentów, u których endarterektomia jest zbyt ryzykowna z powodu współistniejących chorób lub trudno dostępnej lokalizacji zwężenia12.

Podczas zabiegu chirurg wprowadza cewnik przez tętnicę udową lub promieniową do zwężonej tętnicy szyjnej. Następnie rozprężany jest balon, który poszerza zwężone miejsce, po czym umieszczany jest stent (metalowa siateczka), który utrzymuje tętnicę w stanie otwartym12.

Przed zabiegiem zalecana jest podwójna terapia przeciwpłytkowa (DAPT) z aspiryną (75-325 mg/dziennie) i klopidogrelem (75 mg/dziennie)1. U pacjentów po CAS terapia przeciwpłytkowa (cilostazol) może zmniejszyć progresję zwężenia tętnicy szyjnej po implantacji stentu1.

Rewaskularyzacja przez tętnicę szyjną (TCAR)

TCAR (TransCarotid Artery Revascularization) to nowsza, mniej inwazyjna metoda leczenia zwężenia tętnicy szyjnej, szczególnie zalecana dla pacjentów z wysokim ryzykiem okołooperacyjnym12.

Procedura ta łączy elementy techniki otwartej i wewnątrznaczyniowej. Polega na wykonaniu małego nacięcia u podstawy szyi i wprowadzeniu stentu do tętnicy szyjnej. Podczas umieszczania stentu przepływ krwi przez tętnicę szyjną jest tymczasowo odwrócony, co pomaga chronić mózg przed potencjalnymi zatorami, które mogłyby prowadzić do udaru12.

Badania wykazały, że tymczasowe odwrócenie przepływu krwi podczas TCAR jest bezpieczne, a sama procedura wiąże się z niższym ryzykiem udaru niż tradycyjne stentowanie czy operacja otwarta1. Pacjenci po TCAR zazwyczaj szybciej dochodzą do zdrowia, odczuwają mniej bólu i mają mniejsze blizny w porównaniu do tradycyjnej endarterektomii1.

Wybór odpowiedniej metody leczenia

Wybór metody leczenia choroby tętnic szyjnych powinien być indywidualnie dostosowany do każdego pacjenta, uwzględniając wiele czynników12:

  • Stopień zwężenia tętnicy szyjnej (% stenozy)
  • Obecność objawów neurologicznych (TIA, udar)
  • Wiek pacjenta i ogólny stan zdrowia
  • Współistniejące choroby
  • Ryzyko okołooperacyjne

Zgodnie z obecnymi wytycznymi123:

  • Pacjenci bezobjawowi ze zwężeniem <50% – leczenie zachowawcze (modyfikacja stylu życia i farmakoterapia)
  • Pacjenci bezobjawowi ze zwężeniem 60-70% lub większym – można rozważyć endarterektomię, jeśli ryzyko okołooperacyjne jest niskie (<3%)
  • Pacjenci objawowi ze zwężeniem 50-69% – można rozważyć endarterektomię, szczególnie u mężczyzn
  • Pacjenci objawowi ze zwężeniem 70-99% – zalecana endarterektomia, jeśli ryzyko okołooperacyjne jest akceptowalne (<6%)
  • Pacjenci z wysokim ryzykiem chirurgicznym – można rozważyć stentowanie tętnicy szyjnej lub TCAR

Ważne jest, aby interwencja naczyniowa (CEA lub CAS) u pacjentów z objawowym zwężeniem tętnicy szyjnej była przeprowadzona jak najszybciej, najlepiej w ciągu 14 dni od wystąpienia objawów, ponieważ największe ryzyko ponownego udaru występuje w ciągu pierwszych 7-14 dni12.

Postępowanie po zabiegu

Po leczeniu inwazyjnym choroby tętnic szyjnych ważne jest123:

  • Kontynuacja terapii przeciwpłytkowej
  • Regularne przyjmowanie leków obniżających poziom cholesterolu i ciśnienie tętnicze
  • Modyfikacja stylu życia (dieta, aktywność fizyczna, zaprzestanie palenia)
  • Okresowe badania kontrolne, w tym badania ultrasonograficzne (USG duplex) tętnic szyjnych

Warto podkreślić, że choroba tętnic szyjnych nie może być całkowicie wyleczona, ale odpowiednie leczenie może znacznie zmniejszyć ryzyko udaru mózgu i poprawić jakość życia pacjentów1.

Skuteczność leczenia

Leczenie choroby tętnic szyjnych może znacząco zmniejszyć ryzyko udaru mózgu12:

  • Endarterektomia tętnicy szyjnej (CEA) może zmniejszyć ryzyko udaru nawet o 80% u pacjentów z największym ryzykiem1
  • U pacjentów objawowych z ciężkim zwężeniem (70-99%) CEA zmniejsza bezwzględne ryzyko udaru o około 16% w ciągu 5 lat, co oznacza, że trzeba wykonać około 8 zabiegów, aby zapobiec jednemu udarowi1
  • U pacjentów bezobjawowych korzyść z CEA jest mniejsza – zmniejszenie bezwzględnego ryzyka udaru o około 1% rocznie, co oznacza, że trzeba wykonać około 19 zabiegów, aby zapobiec jednemu udarowi lub zgonowi w ciągu 5 lat1

Wyniki leczenia choroby tętnic szyjnych są zazwyczaj dobre, większość pacjentów szybko powraca do zdrowia, często wymagając tylko jednodniowego pobytu w szpitalu12.

Wybór odpowiedniej metody leczenia choroby tętnic szyjnych

Decyzja o wyborze konkretnej metody leczenia choroby tętnic szyjnych powinna być podejmowana przez wielodyscyplinarny zespół specjalistów, w skład którego wchodzą neurolog, chirurg naczyniowy i kardiolog interwencyjny12. W procesie decyzyjnym należy uwzględnić korzyści i ryzyko związane z każdą metodą leczenia oraz indywidualne preferencje pacjenta1.

Warto podkreślić, że nie każde zwężenie tętnicy szyjnej wymaga leczenia zabiegowego, ponieważ same procedury wiążą się z pewnym ryzykiem. Chirurdzy zalecają zabiegi tylko wtedy, gdy ryzyko związane z ciężkim zwężeniem i/lub udarem jest wyższe niż ryzyko związane z procedurą1.

Szybkie i właściwe leczenie choroby tętnic szyjnych może uratować życie i zapobiec poważnym powikłaniom neurologicznym12.

Kolejne rozdziały

Zapraszamy do dalszego czytania naszego leksykonu.

Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.

  1. 10.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Carotid artery disease – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/carotid-artery-disease/diagnosis-treatment/drc-20360527
    The goal in treating carotid artery disease is to prevent stroke. Treatment depends on how blocked the carotid arteries are, whether the blockage is causing symptoms, and the age and other illnesses of the person who has the blockage. […] Treatment for mild to moderate blockage might involve: […] Lifestyle changes to slow the buildup of fatty deposits. These might include quitting smoking, losing weight, eating healthy foods, reducing salt and exercising regularly. […] Medicines to control blood pressure or lower cholesterol. This might include taking a daily aspirin or other blood-thinning medicine to prevent blood clots. […] For severe blockage or for people who’ve had a TIA or stroke, treatment might involve removing the blockage. The options include: […] Carotid endarterectomy. This is the most common treatment for severe carotid artery disease. After cutting along the front of the neck, a surgeon opens the blocked carotid artery and removes the plaques. The surgeon uses stitches or a graft to repair the artery.
  • #1 Atherosclerotic Disease of the Carotid Artery Treatment & Management: Risk Factor Modification, Pharmacologic Therapy, Carotid Endarterectomy
    https://emedicine.medscape.com/article/463147-treatment
    Lifestyle or medical interventions are implemented in order to address the following risk factors: […] Aspirin (30-1350 mg/day) irreversibly acetylates the cyclooxygenase of platelets, thus inhibiting platelet synthesis of thromboxane A2. […] Statin therapy, with a target low-density lipoprotein (LDL) level below 100 mg/dL, is recommended for all patients with extracranial carotid atherosclerotic disease. […] Antiplatelet therapy (cilostazol) may reduce the progression of carotid artery stenosis after stent implantation. […] The following are indications for carotid endarterectomy (CEA), based on prospective randomized trials: […] For the indications listed above, medical management was found to be inferior to CEA. […] Transcarotid artery revascularization (TCAR) represents an alternative to transfemoral CAS in patients deemed to be at high risk for CEA because of the presence of medical comorbidities or certain high-risk anatomic factors (eg, high carotid bifurcation, previous neck surgery, or previous irradiation).
  • #1 Treatment of Carotid Artery Stenosis: Medical Therapy, Surgery, or Stenting?
    https://pmc.ncbi.nlm.nih.gov/articles/PMC2665982/
    The use of a statin medication should be considered even for patients with mild or moderate hypercholesterolemia, with the goal of decreasing the low-density lipoprotein cholesterol value to less than 70 mg/dL. […] In patients with symptomatic carotid artery disease, CEA is effective in preventing future ipsilateral ischemic events, provided that the perioperative combined risk of stroke and death is not higher than 6%. […] Traditionally, surgeons have been reluctant to operate within 1 month of a qualifying TIA or a minor stroke because of a perceived higher risk of periprocedural complications with this timeline than with a later one. […] With the wide availability of various noninvasive diagnostic modalities, most patients who receive a diagnosis of carotid disease are asymptomatic.
  • #1 Carotid Artery Disease | Cedars-Sinai
    https://www.cedars-sinai.org/health-library/diseases-and-conditions/c/carotid-artery-disease.html
    Lowering blood sugar. High blood sugar (glucose) can cause damage to the lining of the carotid arteries. Control glucose levels through a low-sugar diet, and regular exercise. If you have diabetes, you may need medicine or other treatment. […] Exercising. Lack of exercise can cause weight gain. It can raise blood pressure and cholesterol. Exercise can help you keep a healthy weight and reduce risks for carotid artery disease. […] Lowering blood pressure. High blood pressure causes wear and tear and inflammation in blood vessels. This raises the risk for artery narrowing. Blood pressure should be below 140/90 mm/Hg for most people. People with diabetes may need even lower blood pressure. […] Medicines that may be used include: […] Antiplatelets. These medicines make platelets in the blood less able to stick together and cause clots. These medicines include aspirin, clopidogrel, and dipyridamole.
  • #1 Medical and Surgical Management of Symptomatic and Asymptomatic Carotid Artery Stenosis: A Comprehensive Literature Review
    https://pmc.ncbi.nlm.nih.gov/articles/PMC10491926/
    Lipid-lowering therapy with statins, with or without ezetimibe, is recommended for the long-term prevention of stroke and cardiovascular events in patients with symptomatic carotid stenosis and atherosclerotic cardiovascular disease. […] Aspirin is the most commonly prescribed antiplatelet medication and should be initiated promptly. […] For patients undergoing CEA, adding clopidogrel to aspirin increases the risk of hemorrhagic complications and may affect hemostasis. […] For patients with symptomatic carotid stenosis who are not suitable candidates for carotid interventions, it is recommended to use short-term aspirin with clopidogrel for 21 days, followed by clopidogrel monotherapy, or long-term aspirin with modified-release dipyridamole. […] The implementation of best medical treatment (BMT) is considered the fundamental approach in managing patients with both asymptomatic and symptomatic carotid artery stenosis.
  • #1 Atherosclerotic Disease of the Carotid Artery Treatment & Management: Risk Factor Modification, Pharmacologic Therapy, Carotid Endarterectomy
    https://emedicine.medscape.com/article/463147-treatment
    Dual antiplatelet therapy (DAT) with aspirin (75-325 mg/day) and clopidogrel (75 mg/day), initiated prior to the procedure, is strongly recommended. […] Cranial nerve injuries occur in 2-7% of patients. Recurrent laryngeal and hypoglossal nerve dysfunctions are the most common. Postoperative stroke occurs in 1-5% of patients.
  • #1 Carotid artery disease – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/carotid-artery-disease/diagnosis-treatment/drc-20360527
    Carotid angioplasty and stenting. This treatment is for blockages too hard to reach with carotid endarterectomy or for people who have other health conditions that make surgery too risky. This involves a local numbing medicine, known as anesthesia. […] A surgeon uses a tube, known as a catheter, to send a tiny balloon to the area of the clog. The surgeon inflates the balloon to widen the artery. Then the surgeon puts in a small wire mesh coil, known as a stent, to keep the artery from narrowing again.
  • #1 Carotid artery disease – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/carotid-artery-disease/diagnosis-treatment/drc-20360527
    In carotid endarterectomy, a surgeon opens the carotid artery to remove the plaques that block it. […] In carotid angioplasty, a surgeon sends a long, hollow tube, known as a catheter, through the arteries to the narrowed carotid artery in the neck. The surgeon puts in a filter to catch any debris that may break off during the procedure. Then, the surgeon inflates a tiny balloon at the end of the tube to open the narrowed area. […] In carotid stenting, a surgeon sends a long, hollow tube, known as a catheter, through the arteries to the narrowed carotid artery in the neck. The surgeon then puts a small wire mesh coil, known as a stent, into the vessel to keep the artery from narrowing again. Finally, the surgeon removes the tube and the filter that was used to catch debris that might have broken off during the procedure.
  • #1 Mayo Clinic Q and A: New treatment to open blocked carotid artery – Mayo Clinic News Network
    https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-new-treatment-to-open-blocked-carotid-artery/
    If the blockage is too difficult to reach using surgery, or if a patient has other health conditions that make surgery too risky, another option is carotid angioplasty and stenting. For this procedure, a catheter with a tiny balloon at the tip is threaded through an artery in the groin up to the area of the clog. The balloon is inflated to widen the artery, pushing the plaque to the side, and a small wire mesh coil, called a stent, is inserted to keep the artery open. […] The new TCAR technique is a hybrid of the two techniques. It involves making a tiny incision at the base of the neck and, from there, inserting a stent into the carotid artery. While the stent is being placed, blood flow through the carotid artery is reversed temporarily. This is accomplished by inserting a small device into the carotid artery that removes the blood and reroutes it to a vein in the leg via a circuit outside the body.
  • #1 Mayo Clinic Q and A: New treatment to open blocked carotid artery – Mayo Clinic News Network
    https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-new-treatment-to-open-blocked-carotid-artery/
    With TCAR, a stent can be placed to open the artery and relieve the blockage, while the brain is protected from any debris that could lead to a stroke. […] Research has shown that the temporary reversal of blood flow during TCAR is safe. And the treatment has been shown to have a lower stroke risk than traditional stenting or surgery. Although it’s not the best option for everyone, TCAR can be an attractive treatment alternative for many people who have severe carotid stenosis and are at high risk for stroke.
  • #1
    https://consultqd.clevelandclinic.org/innovations-in-the-treatment-of-carotid-artery-stenosis
    Until recent years, open carotid endarterectomy (CEA) has been the standard of care for many patients with severe or symptomatic carotid stenosis. […] However, minimally invasive procedures such as transfemoral carotid stenting and now transcarotid artery revascularization (TCAR) have emerged as safe and effective minimally invasive alternatives for patients with carotid disease. […] TCAR is a less invasive, clinically proven, approved treatment option for carotid artery disease. […] The postoperative course is very important for faster recovery after carotid surgery. […] When compared to traditional open CEA, studies have shown that patients undergoing TCAR usually recover quickly with less pain and smaller scars. […] Proper selection and identification of patients who are candidates for TCAR is critical. […] Since 2022, Cleveland Clinic Weston Hospital has performed TCAR routinely using a minimally invasive approach. […] Our expertise in open vascular surgery and CEA combined with newer, advanced endovascular techniques such as TCAR, has translated into the best possible patient outcomes.
  • #1 Carotid Artery Stenosis: Causes, Symptoms and Treatment
    https://my.clevelandclinic.org/health/diseases/16845-carotid-artery-disease-carotid-artery-stenosis
    Carotid artery stenosis, also called carotid artery disease, is a condition that can lead to stroke. One treatment option for carotid artery stenosis is a surgical procedure call endarterectomy. […] The main goal of carotid artery stenosis treatment is to halt the progression of the disease. This starts with lifestyle modifications including a healthy diet, exercise and stopping smoking. A daily baby dose of aspirin along with medications that lower blood pressure and cholesterol may also be used. […] In more severe cases and or cases causing symptoms of TIA or stroke, your provider may use a surgical procedure called carotid endarterectomy to remove the plaque from the carotid artery through an incision. Alternatively, your surgeon may place a stent through a large needle puncture and ultimately through the blocked artery. This will open the artery up to its proper size while trapping the plaque away from the blood flow between the stent and the wall. A vascular surgeon or specialist determines which of these procedures is best for each person who needs treatment for carotid disease.
  • #1
    https://www.nhs.uk/conditions/carotid-endarterectomy/why-its-done/
    A carotid endarterectomy may be needed if one or both of your carotid arteries become narrowed because of a build-up of fatty deposits (plaque). […] The National Institute for Health and Care Excellence (NICE) recommends that people who have had a stroke or TIA and have a moderate or severe stenosis should have a carotid endarterectomy. […] Having surgery gives the best chance of preventing a further stroke if it’s performed as soon as possible. […] Surgery is sometimes recommended for people who haven’t previously had a stroke or a TIA but are found to have severe stenosis. […] Surgery isn’t recommended in cases where there’s minor stenosis (less than 50%). […] This is because surgery is most beneficial for people with moderate and severe stenosis (more than 50%). […] The maximum benefit is seen in those with severe stenosis (70 to 99%). […] A carotid endarterectomy isn’t of any benefit for people with a complete blockage of their carotid artery.
  • #1 Medical and Surgical Management of Symptomatic and Asymptomatic Carotid Artery Stenosis: A Comprehensive Literature Review
    https://pmc.ncbi.nlm.nih.gov/articles/PMC10491926/
    Carotid artery stenosis is a condition where the carotid artery is blocked by fatty cholesterol deposits called plaque, increasing the risk of stroke. […] Treatment options include medical and surgical interventions, such as carotid endarterectomy (CEA) and carotid artery stenting (CAS). […] Surgical procedures, such as carotid endarterectomy (CEA) and carotid artery stenting (CAS), are available. […] CEA is a commonly performed surgical procedure for treating carotid artery stenosis. During this procedure, the surgeon opens the artery and removes plaque. […] In recent years, CAS has emerged as an alternative to CEA, especially for patients under 70 years old, as minimally invasive endovascular techniques have advanced. […] For patients with high-grade carotid artery stenosis, whether symptomatic or asymptomatic, it is recommended to perform carotid interventions (either CAS or CEA) as soon as possible because the highest risk of recurrent stroke occurs within the first seven to 14 days after the onset of symptoms.
  • #1 Carotid Artery Stenosis: Causes, Symptoms and Treatment
    https://my.clevelandclinic.org/health/diseases/16845-carotid-artery-disease-carotid-artery-stenosis
    Not every carotid stenosis needs surgical or interventional treatment as these procedures themselves come with risk. Surgeons only recommend procedures to people when the risks of severe stenosis and/or stroke become higher than the risk of the procedure. […] Quick treatment of carotid artery stenosis can be lifesaving. When indicated, the outcomes of surgery and stenting are excellent. Most people recover very quickly with just an overnight hospital stay.
  • #1 Carotid Artery Disease Treatment Sydney | CAD | Sydney
    https://www.sydneyvascularsurgery.com.au/carotid-artery-disease.html
    Carotid Stenting is the insertion of a stent (a fine metal cylindrical scaffold) through a small incision in the groin. […] Stenting is usually reserved for patients who cannot undergo a Carotid Endarterectomy. […] Unfortunately, Carotid Artery Disease cannot be cured, but rather, treated with surgery, adjustment of lifestyle factors and the taking of blood thinning medications. […] By doing this on a regular basis, you and your doctor can identify if your disease is recurring or progressing and offer adjustments to your treatment.
  • #1
    https://www.nhs.uk/conditions/carotid-endarterectomy/
    Carotid endarterectomy is a surgical procedure to remove a build-up of fatty deposits (plaque), which cause narrowing of a carotid artery. […] Carotid endarterectomies are carried out when 1 or both carotid arteries become narrowed because of a build-up of fatty deposits (plaque). […] This is known as carotid artery disease or carotid artery stenosis. […] A carotid endarterectomy can significantly reduce the risk of a stroke in people with severely narrowed carotid arteries. […] In people who have previously had a stroke or a TIA, surgery can significantly reduce their risk of having another stroke or TIA. […] Carotid endarterectomy is the main treatment for narrowing of the carotid arteries, but sometimes an alternative procedure called carotid artery stent placement may be available. […] Current guidelines recommend that a carotid endarterectomy should be the first line of treatment for most people.
  • #1 Carotid Artery Treatment Glendale AZ – Prevent Stroke Glendale
    https://www.veinandvascularsurgery.com/learning-center/carotid-artery-disease/
    Carotid artery disease blocks the arteries to the brain and is a leading cause of stroke. Dr. Zakhary has vast experience in treating carotid artery disease. […] The most common treatment for carotid stenosis is carotid endarterectomy. Successful treatment involves good pre-operative diagnosis and workup, good operative technique, and good perioperative care. Dr. Zakhary provides all three of these components of care which results in excellent surgical outcomes. […] Carotid endarterectomy surgery has been shown to reduce the risk of stroke by up to 80 percent in people at the greatest risk. […] These surgeries also are very effective for lowering the risk of a first-time stroke. […] For patients with this degree of blockage, medication and lifestyle changes likely have not been successful in reducing plaque buildups.
  • #1 When to Operate in Carotid Artery Disease | AAFP
    https://www.aafp.org/pubs/afp/issues/2000/0115/p400.html
    Through the removal of atherosclerotic plaques, carotid endarterectomy restores cerebral blood flow and reduces the risk of cerebral ischemia. Results from three major prospective contemporary studies provide compelling evidence for the benefit of carotid endarterectomy, when performed by experienced surgeons, in improving the chance of stroke-free survival in high-risk symptomatic patients. […] Overall, an estimated eight carotid endarterectomies are required to prevent one stroke in symptomatic patients with severe (more than 70 percent) carotid artery stenosis. […] Carotid endarterectomy was also beneficial and not more dangerous in symptomatic patients with atheromatous carotid artery pseudo-occlusion. […] Timely surgical intervention reduces the risk of recurrent cerebral ischemia or death from stroke in patients with hemispheric TIAs, amaurosis fugax or completed carotid-territory nondisabling strokes within the previous six months that were associated with diameter-reducing carotid stenosis of 70 to 99 percent.
  • #1 When to Operate in Carotid Artery Disease | AAFP
    https://www.aafp.org/pubs/afp/issues/2000/0115/p400.html
    The usefulness of carotid endarterectomy in symptomatic patients with carotid artery stenosis of 30 to 69 percent has not yet been unequivocally determined. […] Despite the ACAS findings, some investigators still feel that insufficient evidence exists to recommend surgery in asymptomatic patients. […] It is estimated that 19 carotid endarterectomies must be performed to prevent one stroke or death over a five-year period among asymptomatic patients. […] Because of the low risk of stroke in asymptomatic patients, some experts recommend surgery only when the degree of stenosis is more than 80 percent, as was demonstrated by ECST investigators. […] The overall benefit of carotid endarterectomy strongly depends on surgical risk. Appropriate patient selection and preoperative control of risk factors remain key issues for the family physician to consider.
  • #1 Carotid artery disease | Stroke Association
    https://www.stroke.org.uk/stroke/types/ischaemic/carotid-artery-disease
    There are two main surgical procedures for carotid artery disease: Carotid endarterectomy and Carotid artery stenting. […] Carotid endarterectomy is an operation to remove the inner lining of your artery. It can be done under local or general anaesthetic. The operation takes around one to two hours. […] Stenting uses a mesh cylinder to keep the artery open. Unlike endarterectomy, it doesn’t involve opening up the neck. It’s done under local anaesthetic. […] Your doctor should work with you to help you understand why you need the operation, and what the benefits are. They should also explain the risks, and what to expect afterwards.
  • #2 Treatment of Carotid Artery Stenosis: Medical Therapy, Surgery, or Stenting?
    https://pmc.ncbi.nlm.nih.gov/articles/PMC2665982/
    With the aging of the general population and the availability of noninvasive imaging studies, carotid artery stenosis is a disease commonly seen in general medical practice. […] Antiplatelet therapy and aggressive treatment of vascular risk factors are the mainstays of medical therapy. Class I evidence shows that carotid endarterectomy (CEA) is effective in preventing ipsilateral ischemic events in patients with symptomatic moderate- and high-grade stenosis. […] Recently, carotid angioplasty and stenting (CAS) was proposed as a valid alternative to CEA. […] Prompt evaluation and triage of patients with symptomatic carotid artery stenosis are essential to minimize the risk of early recurrent cerebrovascular events. […] Patients with symptomatic severe carotid artery stenosis should undergo invasive treatment unless the risk of the intervention is considered to be prohibitively high.
  • #2 Carotid Artery Stenosis – Diagnosis and Treatment
    https://www.radiologyinfo.org/en/info/carotidstenosis
    Your doctor may use carotid ultrasound, CT angiography (CTA), magnetic resonance angiography (MRA), or cerebral angiography to determine the presence, location, and severity of stenosis. Treatment to improve or restore blood flow may include angioplasty and vascular stenting or, in severe cases, surgery. […] If blockage is mild to moderate, lifestyle modification and certain medications may be recommended to slow the progression of atherosclerosis: Recommendations include quitting smoking, losing weight, dietary modifications to include healthy foods, reducing salt and exercising regularly. Your doctor may also recommend taking a daily aspirin or other blood-thinning medication to prevent blood clots. […] If blockage is severe, surgical treatment may be recommended: Severe cases of stenosis often require carotid endarterectomy. A surgeon makes an incision to remove plaque and any diseased portion of the artery while the patient is under general anesthesia. A less invasive option used for severe stenosis is carotid artery angioplasty and stenting. During this procedure, the doctor threads a catheter from an incision in the groin to the site of the blockage. Once there, they inflate a balloon tip to open the artery. The doctor may place a stent in the artery to expand it and hold it open.
  • #2 Manage carotid artery disease risk – Mayo Clinic Health System
    https://www.mayoclinichealthsystem.org/hometown-health/speaking-of-health/manage-your-risk-of-carotid-artery-disease
    Carotid artery disease occurs when the blood vessels supplying your brain and head, known as carotid arteries, are damaged or blocked by fatty deposits. […] Preventing a stroke is the primary goal of treating carotid artery disease. A treatment plan will be based on the degree of blockage in your carotid arteries and could include a combination of lifestyle modifications, medications and surgery. […] Treatment for mild to moderate blockages may include lifestyle changes to slow the progression of damage to your arteries, including quitting smoking, losing weight, reducing salt intake and exercising regularly. Medication to control blood pressure, lower cholesterol or prevent blood clots also may be recommended. […] Your care team may recommend removing the blockage from the artery if it is causing severe narrowing or if you have already had a stroke or TIA.
  • #2 Medical and Surgical Management of Symptomatic and Asymptomatic Carotid Artery Stenosis: A Comprehensive Literature Review
    https://pmc.ncbi.nlm.nih.gov/articles/PMC10491926/
    Lipid-lowering therapy with statins, with or without ezetimibe, is recommended for the long-term prevention of stroke and cardiovascular events in patients with symptomatic carotid stenosis and atherosclerotic cardiovascular disease. […] Aspirin is the most commonly prescribed antiplatelet medication and should be initiated promptly. […] For patients undergoing CEA, adding clopidogrel to aspirin increases the risk of hemorrhagic complications and may affect hemostasis. […] For patients with symptomatic carotid stenosis who are not suitable candidates for carotid interventions, it is recommended to use short-term aspirin with clopidogrel for 21 days, followed by clopidogrel monotherapy, or long-term aspirin with modified-release dipyridamole. […] The implementation of best medical treatment (BMT) is considered the fundamental approach in managing patients with both asymptomatic and symptomatic carotid artery stenosis.
  • #2 Atherosclerotic Disease of the Carotid Artery Treatment & Management: Risk Factor Modification, Pharmacologic Therapy, Carotid Endarterectomy
    https://emedicine.medscape.com/article/463147-treatment
    Lifestyle or medical interventions are implemented in order to address the following risk factors: […] Aspirin (30-1350 mg/day) irreversibly acetylates the cyclooxygenase of platelets, thus inhibiting platelet synthesis of thromboxane A2. […] Statin therapy, with a target low-density lipoprotein (LDL) level below 100 mg/dL, is recommended for all patients with extracranial carotid atherosclerotic disease. […] Antiplatelet therapy (cilostazol) may reduce the progression of carotid artery stenosis after stent implantation. […] The following are indications for carotid endarterectomy (CEA), based on prospective randomized trials: […] For the indications listed above, medical management was found to be inferior to CEA. […] Transcarotid artery revascularization (TCAR) represents an alternative to transfemoral CAS in patients deemed to be at high risk for CEA because of the presence of medical comorbidities or certain high-risk anatomic factors (eg, high carotid bifurcation, previous neck surgery, or previous irradiation).
  • #2 Medical and Surgical Management of Symptomatic and Asymptomatic Carotid Artery Stenosis: A Comprehensive Literature Review
    https://pmc.ncbi.nlm.nih.gov/articles/PMC10491926/
    BMT includes various interventions, such as the use of statins for dyslipidemia, smoking cessation, weight management, glycemic control in diabetic patients, hypertension management, antiplatelet therapy (e.g., low-dose aspirin), and promoting an overall healthy lifestyle. […] The latest guideline from the European Society for Vascular Surgery (ESVS) recommends behavioral counseling regarding a healthy diet, smoking cessation, physical activity, and antihypertensive treatment for patients with asymptomatic and symptomatic carotid disease. […] Prophylactic CEA in patients with asymptomatic carotid stenosis has been shown in randomized studies to moderately reduce the incidence of stroke compared to medical therapy alone, provided that the procedure’s morbidity and mortality rates do not exceed 3%.
  • #2 Carotid artery disease – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/carotid-artery-disease/diagnosis-treatment/drc-20360527
    Carotid angioplasty and stenting. This treatment is for blockages too hard to reach with carotid endarterectomy or for people who have other health conditions that make surgery too risky. This involves a local numbing medicine, known as anesthesia. […] A surgeon uses a tube, known as a catheter, to send a tiny balloon to the area of the clog. The surgeon inflates the balloon to widen the artery. Then the surgeon puts in a small wire mesh coil, known as a stent, to keep the artery from narrowing again.
  • #2
    https://www.nhs.uk/conditions/carotid-endarterectomy/
    Carotid endarterectomy is a surgical procedure to remove a build-up of fatty deposits (plaque), which cause narrowing of a carotid artery. […] Carotid endarterectomies are carried out when 1 or both carotid arteries become narrowed because of a build-up of fatty deposits (plaque). […] This is known as carotid artery disease or carotid artery stenosis. […] A carotid endarterectomy can significantly reduce the risk of a stroke in people with severely narrowed carotid arteries. […] In people who have previously had a stroke or a TIA, surgery can significantly reduce their risk of having another stroke or TIA. […] Carotid endarterectomy is the main treatment for narrowing of the carotid arteries, but sometimes an alternative procedure called carotid artery stent placement may be available. […] Current guidelines recommend that a carotid endarterectomy should be the first line of treatment for most people.
  • #2 Medical and Surgical Management of Symptomatic and Asymptomatic Carotid Artery Stenosis: A Comprehensive Literature Review
    https://pmc.ncbi.nlm.nih.gov/articles/PMC10491926/
    If the combined risk of stroke and mortality during the perioperative period is less than 6%, CEA can effectively prevent future ischemic events on the same side of the brain in individuals with symptomatic carotid artery disease. […] Medical Management […] After experiencing a TIA or minor stroke, it is important to promptly evaluate the condition and initiate early preventive treatments, as this can significantly reduce the risk of early recurrence of stroke by approximately 80%. […] Invasive therapy should be considered for patients with symptomatic severe carotid artery stenosis, unless there are significant risks involved, such as severe cardiopulmonary disease, recent large cerebral infarction, or hemorrhagic conversion. […] Antiplatelet therapy and intensive management of vascular risk factors should also be initiated immediately, as they play a crucial role in preventing recurrent strokes following carotid revascularization.
  • #2 Treatment of Carotid Artery Stenosis: Medical Therapy, Surgery, or Stenting?
    https://pmc.ncbi.nlm.nih.gov/articles/PMC2665982/
    The decision on whether to implement invasive treatment in patients with asymptomatic carotid artery stenosis is a difficult one. […] The criterion standard for invasive treatment of carotid artery stenosis is CEA. Recently, CAS has been proposed as a valid alternative to CEA. […] While clinicians await the conclusion of the large RCTs, CAS should be considered for patients with indication for carotid revascularization and high surgical risk. […] Carotid artery stenosis is a problem commonly seen in clinical practice. Differentiation between symptomatic and asymptomatic patients with carotid artery stenosis is essential to tailor therapy properly. Antiplatelet drug therapy and aggressive correction of risk factors are the mainstays of medical therapy.
  • #2 Carotid Artery Stenosis: Symptoms, Treatment | Mass General Brigham
    https://www.massgeneralbrigham.org/en/patient-care/services-and-specialties/heart/conditions/carotid-artery-stenosis
    Carotid artery blockage treatment often requires a multi-step approach. A combination of medications, surgical procedures, and lifestyle changes may all be part of carotid artery treatment without surgery. […] Lifestyle changes such as losing weight, quitting smoking, reducing salt intake, regular exercise, and a heart-healthy diet are all recommended to slow the progression of stenosis. Regular visits to the doctor are also necessary to monitor progress. […] Carotid endarterectomy is a surgical procedure to remove the fatty buildup and plaque in the arteries. The surgeon makes an incision in the neck, and the plaque is removed to open up the clogged arteries. The incision is closed either with stitches or a patch. This surgical procedure is often used in severe cases of blockage. […] Carotid angioplasty and stenting is another method to remove the blockage from the carotid arteries. This procedure opens the clogged arteries so blood flow to the brain can return to normal. A catheter is used to open the artery and restore blood flow. Stenting with a small metal coil keeps the artery open and decreases the chance of it collapsing. Usually reserved for more severe blockage cases, angioplasty is considered less invasive than a carotid endarterectomy procedure.
  • #2
    https://consultqd.clevelandclinic.org/innovations-in-the-treatment-of-carotid-artery-stenosis
    Until recent years, open carotid endarterectomy (CEA) has been the standard of care for many patients with severe or symptomatic carotid stenosis. […] However, minimally invasive procedures such as transfemoral carotid stenting and now transcarotid artery revascularization (TCAR) have emerged as safe and effective minimally invasive alternatives for patients with carotid disease. […] TCAR is a less invasive, clinically proven, approved treatment option for carotid artery disease. […] The postoperative course is very important for faster recovery after carotid surgery. […] When compared to traditional open CEA, studies have shown that patients undergoing TCAR usually recover quickly with less pain and smaller scars. […] Proper selection and identification of patients who are candidates for TCAR is critical. […] Since 2022, Cleveland Clinic Weston Hospital has performed TCAR routinely using a minimally invasive approach. […] Our expertise in open vascular surgery and CEA combined with newer, advanced endovascular techniques such as TCAR, has translated into the best possible patient outcomes.
  • #2 Mayo Clinic Q and A: New treatment to open blocked carotid artery – Mayo Clinic News Network
    https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-new-treatment-to-open-blocked-carotid-artery/
    With TCAR, a stent can be placed to open the artery and relieve the blockage, while the brain is protected from any debris that could lead to a stroke. […] Research has shown that the temporary reversal of blood flow during TCAR is safe. And the treatment has been shown to have a lower stroke risk than traditional stenting or surgery. Although it’s not the best option for everyone, TCAR can be an attractive treatment alternative for many people who have severe carotid stenosis and are at high risk for stroke.
  • #2 Carotid Artery Disease – Eau Claire – Mayo Clinic Health System
    https://www.mayoclinichealthsystem.org/locations/eau-claire/services-and-treatments/cardiac-surgery/conditions-and-treatments/carotid-artery-disease
    Carotid artery disease occurs when the blood vessels that deliver blood to your head and brain (carotid arteries) become damaged or diseased. […] The goal in treating carotid artery disease is to prevent stroke. Specific treatments depend on the extent of blockage in your carotid arteries. Treatment of carotid artery disease usually involves a combination of lifestyle changes, medication and sometimes surgery. […] If blockage is mild to moderate, your doctor may recommend: […] Medication to control blood pressure or lower cholesterol. Your doctor may also recommend taking a daily aspirin or other blood-thinning medication to prevent blood clots. […] If blockage is severe, or if you’ve already had a TIA or stroke, your doctor may recommend removing the blockage from the artery. The options include:
  • #2 When to Operate in Carotid Artery Disease | AAFP
    https://www.aafp.org/pubs/afp/issues/2000/0115/p400.html
    Carotid endarterectomy has proved to be beneficial in the prevention of stroke in selected patients. The procedure is indicated in symptomatic patients with carotid-territory transient ischemic attacks or minor strokes who have carotid artery stenosis of 70 to 99 percent. […] With a low surgical risk, carotid endarterectomy provides modest benefit in symptomatic patients with carotid artery stenosis of 50 to 69 percent. […] In the Asymptomatic Carotid Atherosclerosis Study, carotid endarterectomy was beneficial in patients who had asymptomatic carotid artery stenosis of 60 percent or greater and whose general health made them good candidates for elective surgery, provided that the arteriographic and surgical complication rates were low. […] However, in asymptomatic patients, surgery reduced the absolute risk of stroke by only 1 percent per year.
  • #2 Carotid artery disease | Stroke Association
    https://www.stroke.org.uk/stroke/types/ischaemic/carotid-artery-disease
    This page explains what happens when you are diagnosed with narrowing of the blood vessels in your neck (carotid artery disease), and treatments to reduce your risk of a stroke. […] Carotid artery disease can be treated using surgery or medication and lifestyle changes. The treatment you’re offered depends on your individual risk of having another stroke. […] You’ll only be offered a procedure if doctors think it will substantially reduce your risk of having another stroke. If the artery is narrowed by over 50% (also known as moderate to severe stenosis) and doctors think you have a high risk of another stroke, you may be offered a surgical procedure to repair the artery. This should be carried out as soon as possible after your stroke or TIA. […] If your artery is less than 50% narrowed, your medical team may decide that you will benefit from different types of treatment. Medication can be very effective in reducing your risk of a stroke. For example, blood-thinning medication can reduce the risk of another clot forming, and medication for high blood pressure and high cholesterol can reduce the build-up of fatty materials in your arteries. You’ll be given advice about how to make healthy lifestyle changes too.
  • #2 Carotid Artery Stenosis: Causes, Symptoms and Treatment
    https://my.clevelandclinic.org/health/diseases/16845-carotid-artery-disease-carotid-artery-stenosis
    Not every carotid stenosis needs surgical or interventional treatment as these procedures themselves come with risk. Surgeons only recommend procedures to people when the risks of severe stenosis and/or stroke become higher than the risk of the procedure. […] Quick treatment of carotid artery stenosis can be lifesaving. When indicated, the outcomes of surgery and stenting are excellent. Most people recover very quickly with just an overnight hospital stay.
  • #2 Carotid Artery Disease – MU Health Care
    https://www.muhealth.org/conditions-treatments/heart-vascular-care/carotid-artery-disease
    If you are not a good candidate for open surgery, minimally invasive stent procedures can clear the blockage. […] After carotid artery surgery, you will have better blood flow through your carotid arteries and a lower chance of stroke. Generally, recovery takes only a few days before you can return to your normal activities.
  • #2 Carotid Artery Disease Care | Baptist Health South Florida
    https://baptisthealth.net/services/heart-and-vascular-care/services-and-programs/carotid-artery-disease
    Good brain function depends on a steady flow of oxygen-rich blood through the carotid arteries in your neck. If you have a blockage that slows that blood flow down, you have carotid artery disease. And you could be at increased risk for a stroke. At Baptist Health, we have the expertise to help you manage your disease and lower your stroke risk. […] When you come to us for carotid artery disease treatment, you can be confident you’ll receive the most comprehensive, high-quality care available. We bring together a multidisciplinary team of experts who can diagnose your condition and recommend the best therapy options. […] Our multidisciplinary team of experts works together to bring you the right diagnosis and to design a treatment plan that meets your specific needs. By using the most advanced traditional or minimally invasive procedures to treat carotid artery disease, we can reduce stroke risk between 70 and 80 percent.
  • #2 Advanced Treatments for Carotid Artery Stenosis, a Common Cause of Stroke
    https://www.medstarhealth.org/blog/carotid-artery-stenosis-treatment
    Transcarotid artery revascularization (TCAR) is less invasive than the carotid endarterectomy and the latest intervention to treat CAS. […] After surgery, it’s important to stay on your medications and make lifestyle changes to help your heart and blood vessels stay healthy. […] Working with a specialist to treat and manage CAS can significantly reduce the risk of death or long-term impairment from stroke, protecting the brain and preserving its function.
  • #3 Advanced Treatments for Carotid Artery Stenosis, a Common Cause of Stroke
    https://www.medstarhealth.org/blog/carotid-artery-stenosis-treatment
    Medications to treat CAS include: Antiplatelet medicines: Aspirin, clopidogrel, and dipyridamole are all examples of medicines that cause the blood to stick together less, avoiding clots. Cholesterol medicines: Statins like simvastatin and atorvastatin can lower cholesterol. Studies have shown they can also decrease the thickness of the carotid artery wall and increase its opening. Blood-pressure lowering medicines: There are several medications that help lower blood pressure to less than 140/90, which is recommended for most people. […] When the carotid artery is more than 70% narrowed, surgery is usually recommended. […] Carotid endarterectomy (CEA) has been the gold-standard CAS surgery since the 1950s. […] Transfemoral Carotid Artery Stenting (TF-CAS) is a less invasive technique to help clear plaque buildup.
  • #3 Atherosclerotic Disease of the Carotid Artery Guidelines: SVS Guidelines for Management of Extracranial Cerebrovascular Disease
    https://emedicine.medscape.com/article/463147-guidelines
    Carotid endarterectomy (CEA) is recommended as first-line treatment for symptomatic low-risk surgical patients with stenosis of 50-99% and asymptomatic patients with stenosis of 70-99%. […] Carotid revascularization is appropriate for symptomatic patients with recent stable stroke and 50% stenosis. It should be performed as soon as the patient is neurologically stable (after 48 hr but before 14 d from symptom onset). […] In patients with symptomatic carotid stenosis of 50-99% who require both CEA and coronary artery bypass grafting (CABG), CEA before or concomitant with CABG is suggested.
  • #3 Advanced Treatments for Carotid Artery Stenosis, a Common Cause of Stroke
    https://www.medstarhealth.org/blog/carotid-artery-stenosis-treatment
    Transcarotid artery revascularization (TCAR) is less invasive than the carotid endarterectomy and the latest intervention to treat CAS. […] After surgery, it’s important to stay on your medications and make lifestyle changes to help your heart and blood vessels stay healthy. […] Working with a specialist to treat and manage CAS can significantly reduce the risk of death or long-term impairment from stroke, protecting the brain and preserving its function.