Materiały źródłowe

• #1 Vasculitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/vasculitis/symptoms-causes/syc-20363435

  Vasculitis involves swelling and irritation, called inflammation, of blood vessels. The inflammation can cause the walls of the blood vessels to thicken. This thickening can narrow the vessels. If the narrowing restricts blood flow, it can damage organs and tissues. […] Symptoms of most types of vasculitis can include: Fever. Headache. Tiredness. Weight loss. Aches and pains. […] Other symptoms depend on the parts of the body affected: If vasculitis affects the stomach or intestines, there may be pain after eating. Ulcers and tears, called perforations, are possible. They may cause blood in the stool. Dizziness, ringing in the ears and sudden hearing loss may happen. Vasculitis can make the eyes look red. They may itch or burn. Giant cell arteritis can cause double vision and brief or ongoing blindness in one or both eyes. This is sometimes the first sign of the disease. Some types of vasculitis can cause numbness or weakness in a hand or foot. The palms of the hands and soles of the feet might swell or harden. This can cause shortness of breath or coughing up blood. Bleeding under the skin can show up as red spots. Vasculitis also can cause lumps or open sores on the skin. […] Some types of vasculitis get worse quickly. Early diagnosis is the key to getting treatment that works.

• #2 Vasculitis: Symptoms, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/12101-vasculitis

  Vasculitis is a condition that causes inflammation (swelling) in your blood vessels. […] If you have vasculitis, your blood vessels swell and thicken. This makes it harder for blood to flow through them. Over time, the inflammation can damage your organs and cause serious complications like aneurysms. […] Most people with vasculitis can manage their symptoms with medication. But vasculitis can be fatal if you experience severe symptoms that affect blood flow to your organs. […] Some of the most common vasculitis symptoms include: Trouble breathing. Coughing. Numbness or tingling, especially in your hands and feet. Rashes, bumps or areas of discoloration on your skin. Fever. Fatigue or a general feeling of being sick. Weight loss. Weakness. Joint pain. Abdominal (stomach) pain. Kidney problems (including dark pee or blood in your pee). Strokes.

• #3 Vasculitis – Symptoms | NHLBI, NIH

  https://www.nhlbi.nih.gov/health/vasculitis/symptoms

  The symptoms of vasculitis are different depending on the type of vasculitis you have, the blood vessels and organs involved, and whether your condition is serious. Some people may have few symptoms. Other people may become very sick. […] Sometimes, the symptoms develop slowly over months. The symptoms may also develop very quickly over days or weeks. Not everyone will experience the common symptoms below. Some people will experience some, but not all of them. General symptoms of vasculitis include: […] Others may experience common, more specific problems that are caused by vasculitis. […] Blood vessels damaged by vasculitis can narrow and block normal blood flow, which may cause problems in other parts of the body. Some problems can be life-threatening. They include:

• #4 Symptoms of Vasculitis : Johns Hopkins Vasculitis Center

  https://www.hopkinsvasculitis.org/vasculitis/symptoms-vasculitis/

  The symptoms of vasculitis depend on the particular blood vessels (and organs) that are involved by the inflammatory process. […] Patients with vasculitis generally feel sick. They often have fevers, weight loss, fatigue, a rapid pulse, and diffuse aches and pains that are difficult to pinpoint. […] It has been said that vasculitis is a hurting disease, because it is so commonly associated with pain of one type or another: pain from a nerve infarction, pain from insufficient blood to the gastrointestinal tract, pain from skin ulcers. […] Symptoms range from full-blown arthritis to aches in the joints without obvious swelling (arthralgias). […] Cough (particularly coughing up blood), shortness of breath, a pneumonia-like appearance to a patient’s chest X-ray, lung infiltrates, and the development of cavities in the lungs are among the manifestations that may occur in forms of vasculitis with lung involvement.

• #5

  https://rheumatology.org/patients/vasculitis

  Vasculitis symptoms include rashes that could be red spots (purpura), lumps (nodules) or sores (ulcers), headaches with vision changes, shortness of breath, cough, and numbness or weakness in a hand or foot. […] Some patients may have joint pain, fatigue, or sinus problems. […] Vasculitis may seriously affect kidneys without many symptoms initially.

• #6

  https://www.arthritis.org/diseases/vasculitis

  Vasculitis symptoms may occur once or several times over several years. […] Signs and symptoms of vasculitis vary and can range from mild to life-threatening. They depend on the type of vasculitis, the organs involved and how severe the condition is. […] Common symptoms include: Fever. Loss of appetite. Weight loss. Fatigue. General aches and pains. […] Vasculitis can affect organs and body systems, causing a range of signs and symptoms including: Skin purple or red spots or bumps; clusters of small dots, splotches, bruises, or hives; itching. Joints aching or arthritis in one or more joints. Lungs shortness of breath; coughing up blood. Gastrointestinal tract sores in the mouth; stomach pain; in severe cases, blockage of blood flow to the intestines that can cause weakening or rupture of intestines. Sinuses, nose, throat and ears sinus or chronic middle ear infections; sores in the nose; in some cases, hearing loss. Eyes red, itchy, burning eyes; light sensitivity; blurred vision; rarely, blindness. Brain headaches; problems thinking clearly; changes in mental function; stroke-like symptoms, such as muscle weakness and paralysis. Nerves numbness, tingling and weakness in various parts of the body; loss of feeling or strength in hands and feet; shooting pains in arms and legs. […] In severe cases, vasculitis can cause blood vessels to close off, so blood cant flow through or they bulge and possibly burst (aneurysm).

• #7 Symptoms – Vasculitis UK

  https://www.vasculitis.org.uk/about-vasculitis/symptoms

  The symptoms caused by vasculitis will depend on the organs involved. However, some general symptoms include: tiredness, weakness, loss of appetite, weight loss, and fever. Unfortunately many of these symptoms apply to other diseases which make it difficult to diagnose vasculitis. […] Some symptoms encountered, specific to various systems are: […] Respiratory system breathlessness, wheeze, dry cough or coughing up blood […] ENT (Ear, Nose and Throat) hearing problems (deafness and or noises in the ear), nasal crusting, nose bleeds, sinus pain (which may be felt as headaches or pain in the face) or hoarse voice […] Skin rashes, ulcers, and necrosis (death of tissue) […] Eyes red (blood shot) eyes, painful, dry or gritty eyes, visual loss or other changes in vision […] Joints arthralgias (pain in joints), and joint swelling

• #8 What is Vasculitis of the Legs? – Dr. Naveen Bhadauria | Private Rheumatologist Consultant In London

  https://privatelondonrheumatologist.com/what-is-vasculitis-of-the-legs/

  Vasculitis is a general term used to describe a disease that leads to inflammation of blood vessels. When the blood vessels of your legs become inflamed, this is called vasculitis of the legs. […] A patient may show various symptoms according to the severity of the condition. […] The most common symptoms of vasculitis show as red or purple dots on the skin called petechiae. They can appear in large numbers on the legs. You can develop larger red or purple spots around the size of a fingertip. Larger spots are called purpura. […] Larger spots (purpura) can often look like bruises on the skin, but the patient hasn’t knowingly knocked or injured the leg to result in a bruise. Unlike a bruise, purpura doesn’t fade or disappear after a few days. […] While petechiae and purpura are the most common symptoms of vasculitis in the legs, a less common form of vasculitis is where your legs develop hives. This is where the skin on your legs develops itchy raised lumps that can be tender and painful to the touch.

• #9 What is Vasculitis of the Legs? – Dr. Naveen Bhadauria | Private Rheumatologist Consultant In London

  https://privatelondonrheumatologist.com/what-is-vasculitis-of-the-legs/

  In most cases, the cause of vasculitis in the lower legs is unknown. The condition is an inflammation of the blood vessels in the legs, and it occurs when your body’s immune system attacks the blood vessels by mistake. […] Developing vasculitis in the legs can happen after experiencing an infection, virus, disease or a side effect from taking medications to treat a health condition. […] If you already have a weak immune system, you can develop vasculitis in any part of the body. But when vasculitis develops in your legs, the blood vessels become inflamed and can become thicker or narrower. […] The treatment for vasculitis of the legs will depend on the severity of the condition and your individual diagnosis. It is a serious health condition that often requires professional medical treatment and support to control and manage the condition long term.

• #10 Symptoms of Vasculitis : Johns Hopkins Vasculitis Center

  https://www.hopkinsvasculitis.org/vasculitis/symptoms-vasculitis/

  Eleven days later, as the patient’s symptoms worsened, a chest X-ray confirmed progression of her lung hemorrhage. […] In contrast to many other organs, inflammation in the kidneys does not hurt or cause other symptoms a patient would notice until renal damage is quite advanced. […] If renal involvement is not recognized, renal failure can develop, sometimes leading to the need for dialysis or kidney transplant. […] Anemia (low hematocrit or red blood cell count) is a typical finding in patients with active vasculitis. […] Symptoms can include chronic sinus congestion and infections that persist for longer than they should and require repeated courses of antibiotics; bleeding from the nose; perforations (holes) in the nasal septum; hearing loss; inflammatory fluid in the ears requiring drainage; inflammation in the cartilage of the ears or nose.

• #11 ANCA associated vasculitis | The BMJ

  https://www.bmj.com/content/369/bmj.m1070

  Consider ANCA associated vasculitis (AAV) in people with chronic systemic symptoms and evidence of renal, pulmonary, ear, nose, and throat, ophthalmic, or peripheral nerve disease. […] AAV may present with constitutional symptoms suggestive of chronic inflammatory disease (fatigue, weight loss, fever, night sweats, myalgia, or polyarthralgia) or with specific features of end-organ involvement. […] Patients with haemoptysis plus other features of AAV warrant same day hospital assessment to evaluate for pulmonary haemorrhage. […] Almost any part of the body can be affected, but the most commonly affected systems are the upper airways, lungs, kidneys, eyes, and peripheral nerves. […] Therefore, presenting symptoms include sinus pain, nasal discharge, or crusting, ear pain, or deafness (from upper airways involvement), cough, shortness of breath, wheeze or haemoptysis (from lung involvement), and painful, red eyes (from scleritis).

• #12 Symptoms – Vasculitis UK

  https://www.vasculitis.org.uk/about-vasculitis/symptoms

  Nervous system loss of sensation, weakness, unusual painful symptoms in the hands and feet (hotness, pins and needles or electric shocks) and rarely paralysis or stroke […] Gastrointestinal system diarrhoea, bleeding and abdominal pain […] Kidneys/Renal initially no symptoms. However urine dipstick tests will indicate problems with minute amounts of blood or protein in the urine. Occasionally blood may be seen in the urine (red or brown urine) or the amount of urine produced may suddenly reduce or stop altogether.

• #13 Symptoms of Vasculitis : Johns Hopkins Vasculitis Center

  https://www.hopkinsvasculitis.org/vasculitis/symptoms-vasculitis/

  Vasculitis involving the eye may affect either blood vessels to the eyes, causing the sudden loss of vision, or small blood vessels within the eyes, leading to retinal problems, thinning of the sclera (the white part of the eyes), inflammation within the eyes different chambers, and conjunctivitis (pinkeye). […] When present, vasculitis in this site can cause headaches, strokes, changes in mental status, or difficulty with coordination. […] Damage to the peripheral nerves can cause shooting pains in the arms and legs, numbness, and asymmetrical weakness (i.e., weakness that involves one side of the body more than the other).

• #14 Vasculitis: Causes, Symptoms, and Treatments

  https://www.webmd.com/rheumatoid-arthritis/vasculitis-treatment

  You may feel pain after you eat if vasculitis affects your stomach or intestines. You could also see blood in your stool. […] Vasculitis can cause your ears to ring. It could also cause dizziness or sudden loss of hearing. You might also get inner ear infections. […] Vasculitis can cause numbness or weakness in your hands or feet, along with swollen or hardened palms and soles. […] If vasculitis affects your lungs, you could have shortness of breath or maybe cough up blood. […] Vasculitis in this area can cause ulcers or open sores. […] Along with sinus infections and a runny nose, you could also get blisters in your nose. […] Vasculitis can make your lips and tongue swollen and dry, or your mouth and throat swell.

• #15 Vasculitis: Symptoms, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/12101-vasculitis

  Which symptoms you experience depends on which blood vessels are affected and how severe the inflammation is. […] Theres no cure for vasculitis. Once you find treatments that manage your symptoms well, you might enter remission long periods of time between episodes of symptoms. Some people are in remission for months or years before experiencing symptoms again. […] You should expect to manage vasculitis for a long time, maybe for the rest of your life. Even if you dont have severe symptoms, youll need to see a provider regularly to monitor any changes in your blood vessels. […] Even if you enter remission, theres always a chance vasculitis will cause symptoms again in the future.

• #16 General Vasculitis – Vasculitis Foundation

  https://vasculitisfoundation.org/education/general-vasculitis/

  Vasculitis symptoms vary from patient to patient and depend on the type of vasculitis and affected tissues and organs. Symptoms may include: […] It is common for people with vasculitis to experience periods of relapse and remission, so regular doctor visits and follow-up monitoring are recommended. […] Serious vasculitis complications can occur, especially if the disease goes undiagnosed or untreated. Depending on the type of vasculitis and severity of condition, complications can include organ damage or failure, blood clots, an aneurysm (an abnormal bulging of a weakened blood vessel that can burst), heart problems, vision loss, neuropathy, and lung bleeding, among others. […] Even with effective treatment, relapses of vasculitis are common. Regular doctor visits and ongoing monitoring of laboratory and imaging tests are important in detecting relapses early.

• #17 General Vasculitis – Vasculitis Foundation

  https://vasculitisfoundation.org/education/general-vasculitis/

  There is no cure for vasculitis at this time, but with early diagnosis and proper treatment, many patients can lead full, productive lives. Outlook depends on several factors including the form of vasculitis, affected organs, severity of disease, how soon it is diagnosed and treated, and whether there is an underlying condition, among others. Most forms of vasculitis are chronic, with periods of relapse and remission. In addition, medications used to treat vasculitis carry the risk of side effects, so follow-up medical care is essential.

• #18 Vasculitis Frequently Asked Questions : Johns Hopkins Vasculitis Center

  https://www.hopkinsvasculitis.org/resources/vasculitis-faq/

  The course of vasculitis is often difficult to predict. Some types of vasculitis may occur only once and do not return. Other types are prone to recurrences. […] It is important to balance the types of medications necessary to control the disease and the risk of side effects that those medicines often bring. […] After patients achieve remission from their vasculitis, it is logical for them to wonder if their disease will ever return. The answer, which is often difficult to give with certainty, depends in large part on the patients specific type of vasculitis. […] Other forms of vasculitis behave less predictably and never come back in some patients but recur frequently in others. Granulomatosis with polyangiitis (GPA), giant cell arteritis (GCA), Takayasu arteritis, microscopic polyangiitis, and many other types of vasculitis fall into the category of diseases that have periods of quiescence and periods of flare. Disease flares in vasculitis can be mild (rash, minor joint pains) or severe (renal failure, skin ulcers). Flares may occur if medications are discontinued or dosage is lowered.

• #19 Vasculitis | Symptoms, causes | Versus Arthritis

  https://versusarthritis.org/about-arthritis/conditions/vasculitis/

  Most types of vasculitis respond well to treatment, and for many of them you’re likely to make a full recovery, although relapses in the future are possible. […] The outcome depends on the type of vasculitis and how it affects you. Overall, the best way to learn more about what might happen to you in the future is to talk to your doctor or another health professional.

• #20 Vasculitis Frequently Asked Questions : Johns Hopkins Vasculitis Center

  https://www.hopkinsvasculitis.org/resources/vasculitis-faq/

  At the present time, the ability of doctors to predict who will suffer disease flares and who will maintain in long-term remissions (or be cured) needs refinement. Progress in this area will come through research. […] First, the symptoms of flares are usually very similar those experienced at the onset of disease. If headaches signaled the beginning of giant cell arteritis, then the recurrence of headaches may indicate a disease flare. […] Patients must become experts about their own manifestations of vasculitis so that they can recognize them immediately, consult their doctors, and begin appropriate treatment before serious damage occurs.

• #21 Vasculitis – What Is Vasculitis? | NHLBI, NIH

  https://www.nhlbi.nih.gov/health/vasculitis

  With vasculitis, you may experience general symptoms, such as fever, weight loss, tiredness, pain, and rash. […] If you are diagnosed with vasculitis, medicine can help improve your symptoms and help you avoid flares and complications. […] With treatment, vasculitis can go into remission, which is a period of time when the disease is not active. […] Polyarteritis nodosa causes damage, including aneurysm, most often to medium-sized arteries. This type of vasculitis may cause muscle and joint pain, kidney failure, high blood pressure, or symptoms such as abdominal pain, nausea, and vomiting.

• #22 Frequently asked questions – Vasculitis UK

  https://www.vasculitis.org.uk/about-vasculitis/frequently-asked-questions

  As there are a number of different vasculitis diseases and as they can attack most organs of the body the symptoms differ from vasculitis to vasculitis and from patient to patient. Some general symptoms include: tiredness, weakness, loss of appetite, weight loss and fever. […] A flare is where the disease has been relatively stable on maintenance therapy but there is a sudden change in the original symptoms or new symptoms are reported. […] After the initial treatment period, when the physician considers the disease is drug/medication controlled he/she may consider the patient to be in clinical remission. If the disease is considered to be in remission or inactive without drugs/medication, this is normally classed as full remission. […] In some cases of severe disease if not diagnosed early and not treated correctly. With early diagnosis and appropriate treatment vasculitis is now rarely fatal. Many milder cases may cause damage to organs or discomfort but are not life-threatening.

• #23 Vasculitis | Symptoms, causes | Versus Arthritis

  https://versusarthritis.org/about-arthritis/conditions/vasculitis/

  Vasculitis can cause a range of symptoms and possible complications. The amount of damage vasculitis causes depends on which part of the body is affected. […] Many people with vasculitis feel unwell and have fever, sweats, fatigue and weight loss. These can be the first symptoms experienced, so it’s important to be seen by your GP. […] Other symptoms vary according to which part of the body is affected, for example: Skin vasculitis in the skin causes spots that can burst, leaving open sores (ulcers). […] Headaches, pain in the jaw and problems with the eyes can be serious symptoms of giant cell arteritis (GCA). […] The most severe types of vasculitis can be life-threatening. Early diagnosis and treatment is essential for the best chances of avoiding permanent damage to tissues and organs.

• #24 Vasculitis – Symptoms and Diagnosis

  https://www.uofmhealth.org/conditions-treatments/rheumatology/symptoms-and-diagnosis-vasculitis

  There are many types of vasculitis, each capable of restricting the flow of blood to virtually any tissue, organ or structure of the body. This leads to an extensive list of potential symptoms, depending on where the inflammation is occurring or the blood flow is being compromised. […] Symptoms may be mild or severe and may occur only once or return regularly. In some instances, there are no symptoms until the disease is very advanced. […] Early diagnosis and treatment is the best way to avoid severe disease and permanent damage to organs and tissues.

• #25 5 Telltale Signs of Vasculitis | Rheumatology located in Tustin and Laguna Hills, CA | Pacific Rheumatology Center

  https://www.pacificrheumatologycenter.com/post/5-telltale-signs-of-vasculitis

  Early treatment of vasculitis is essential if you want to prevent complications, and learning the signs is the only way to know you should seek help. […] Vasculitis can affect any part of your body and cause a vast range of symptoms. […] The symptoms associated with vasculitis are just as diverse as the numerous body areas affected. […] Your symptoms could range from mild to life-threatening, and they may appear suddenly or develop gradually. […] Even though each type of vasculitis has unique symptoms, they can all cause the following five symptoms: Fever, Fatigue, General aches and pains, Loss of appetite, Weight loss. […] Some types of vasculitis are limited to one location or organ, while others affect multiple body areas. […] When vasculitis affects your skin, you may have a rash, clusters of small red dots, bruises, lumps (nodules), hives, itching, open sores, and red spots caused by bleeding under the skin.

• #26 ANCA associated vasculitis | The BMJ

  https://www.bmj.com/content/369/bmj.m1070

  If promptly recognised, however, AAV responds well to immunosuppressive treatment and has a prognosis akin to other chronic inflammatory diseases. […] The consequences of late diagnosis are particularly apparent in the subset of people who have renal involvement. In this group, delayed diagnosis and worse renal function at presentation are associated with a higher risk of end-stage renal disease and early mortality.

• #27 Vasculitis | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/vasculitis

  Vasculitis, sometimes called angiitis or arteritis, is an umbrella term for more than a dozen conditions, all of which involve inflammation of the blood vessels. […] This autoimmune attack (auto means self) causes the blood vessel wall to become swollen and irritated, called inflammation. Inflamed blood vessels can become narrower or even close off completely. […] Symptoms that may indicate vasculitis is affecting a particular part of the body include: Purplish rashes that dont blanch (fade) when you press on them, Shortness of breath and/or chest pain, Abdominal pain and/or bloating, Joint and muscle pain, Nerve problems (numbness, tingling), Blurring or loss of vision, Headaches, Blood in the urine. […] Because vasculitis attacks the blood vessels, it also has the potential to affect the organs and tissues that depend on those blood vessels for oxygen and other nutrients. This can cause complications ranging from relatively mild (skin ulcers) to very serious (organ failure).

• #28 Vasculitis

  https://www.nhs.uk/conditions/vasculitis/

  Vasculitis can range from a minor problem that just affects the skin, to a more serious illness that causes problems with organs like the heart or kidneys. […] Eosinophilic granulomatosis with polyangiitis, also called Churg-Strauss syndrome, is a type of vasculitis that mainly affects adults around 38 to 54. It can cause: asthma, cold-like symptoms caused by allergies (allergic rhinitis), a high temperature, muscle and joint pain, tiredness, loss of appetite and weight loss. […] Temporal arteritis, also known as giant cell arteritis, is a type of vasculitis where the arteries at the side of the head (the temples) become inflamed. It mostly affects adults over the age of 50 and can cause: aching and soreness around the temples, jaw muscle pain while eating, headaches, double vision or vision loss.

• #29 Vasculitis – Types, Causes and Risk Factors

  https://www.uofmhealth.org/conditions-treatments/rheumatology/types-vasculitis

  Giant cell arteritis (GCA): One of the more common forms of large vessel vasculitis occurring in adults older than age 50. It can present with headaches and/or jaw pain, sometimes with flu-like symptoms, fatigue and fever. GCA can impact blood flow to the eye, resulting in visual disturbance or loss. […] Takayasus arteritis (TAK): An inflammation of the walls of the aorta and its main branches, TAK occurs predominantly in younger women. Reduced blood flow to arms, legs and major organs may cause symptoms of arm or leg pain, elevated blood pressure, discoloration in hands or feet, fatigue, headache, vision problems, chest pain, heart attack or stroke. TAK symptoms may develop slowly over time, making it difficult to diagnose. […] Aortitis can cause fever, weight loss, or pain in the chest, limbs, or abdomen, or can be asymptomatic. If untreated, it can lead to thinning and an outpouching of the aortic wall called an aneurysm.

• #30 Vasculitis

  https://www.nhs.uk/conditions/vasculitis/

  Granulomatosis with polyangiitis, also called Wegener’s granulomatosis, is a type of vasculitis that affects blood vessels in the nose, sinuses, ears, lungs and kidneys. It mainly affects middle-aged or older people and can cause: a high temperature, night sweats, inflammation of the sinuses (sinusitis), nosebleeds and crusting of the nose, shortness of breath and coughing up blood, kidney problems. Granulomatosis with polyangiitis is a serious condition that can be fatal if left untreated, as it can lead to organ failure. […] Microscopic polyangiitis is a rare and potentially serious long-term type of vasculitis that most often develops in middle-aged people. It can affect any organ, but often affects the lungs, kidneys and nerves. It can cause: a rash, shortness of breath and coughing up blood, red and sore eyes, pins and needles or numbness, joint stiffness, muscle aches, loss of appetite, losing weight without trying, feeling tired, flu-like symptoms, such as a high temperature and an aching body, kidney problems.

• #31 Vasculitis – Types, Causes and Risk Factors

  https://www.uofmhealth.org/conditions-treatments/rheumatology/types-vasculitis

  Polyarteritis nodosa (PAN): Inflammation to the blood vessels in the skin, nervous system, kidneys, gastrointestinal tract, heart, and other organs, more commonly in middle aged men. Because it can involve multiple systems in the body, it can present with a wide range of symptoms including fatigue, numbness, high blood pressure, abdominal pain, leg pain and skin sores. […] Granulomatosis with polyangiitis (GPA): Symptoms can also be caused by small areas of inflammation called granulomas in the sinuses, lungs, ear canals and orbits of the eyes. Depending on which system is involved it can present with chronic nasal congestion, shortness of breath, cough and nosebleeds, joint pain, eye pain and redness, trouble hearing, skin rashes, fatigue, fever, weight loss, weakness and numbness. […] Microscopic polyangiitis (MPA): The most common symptoms are blood in the urine and high blood pressure from kidney inflammation, and shortness of breath and coughing up blood from lung inflammation. Weight loss, fever, skin lesions and nerve damage can also occur.

• #32 Vasculitis

  https://www.nhs.uk/conditions/vasculitis/

  Polyarteritis nodosa is a rare type of vasculitis that particularly affects the arteries supplying the gut, kidneys and nerves. It can cause: muscle and joint pain, tummy (abdominal) pain, particularly after eating, a rash, pins and needles or numbness, bleeding and ulcers in the gut. Polyarteritis nodosa can be very serious if it’s not treated. […] Polymyalgia rheumatica is a type of vasculitis that’s closely related to temporal arteritis. It can cause: pain and stiffness in the shoulders, neck and hips, which is often worse after waking up, a high temperature, extreme tiredness, loss of appetite and weight loss, depression. […] Takayasu arteritis is a type of vasculitis that mainly affects young women. It can cause: extreme tiredness, a high temperature, weight loss, muscle and joint pain, painful, numb or cold limbs.

• #33 Vasculitis – Types, Causes and Risk Factors

  https://www.uofmhealth.org/conditions-treatments/rheumatology/types-vasculitis

  Eosinophilic granulomatosis with polyangiitis (EGPA), formally known as Churg-Strauss syndrome: Nearly all EGPA patients have asthma and/or sinus polyps, but additional symptoms depend on which body parts are involved and can include the lungs, sinuses, nerves, heart, skin, and kidneys. […] Primary angiitis of the central nervous system (PACNS): The most common symptoms are headache, brain dysfunction (encephalopathy) and/or recurrent strokes. […] IgA vasculitis (Henoch-Schonlein Purpura – HSP): The most common symptom of HSP is purpura, a red or dark purple rash usually seen on the legs and buttocks. HSP may also cause joint swelling, abdominal pain, and kidney inflammation. […] Cryoglobulinemic vasculitis: Symptoms include purplish patches of skin (purpura), nerve damage, weakness, joint pain, and kidney problems.

• #34 IgA vasculitis – Henoch-Schonlein purpura: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000425.htm

  IgA vasculitis is a disease that involves purple spots on the skin, joint pain, gastrointestinal problems, and glomerulonephritis (a type of kidney disorder). It is also known as Henoch-Schönlein purpura (HSP). […] Symptoms and features of IgA vasculitis may include: Purple spots on the skin (purpura). This occurs in nearly all children with the condition. This most often occurs over the buttocks, lower legs, and elbows. Abdominal pain. Joint pain. Abnormal urine (may have no symptoms). Diarrhea, sometimes bloody. Hives or angioedema. Nausea and vomiting. Swelling and pain in the scrotum of boys. Headache. […] The disease most often gets better on its own. Two thirds of children with IgA vasculitis have only one episode. One third of children have more episodes. People should have close medical follow-up for 6 months after episodes to look for signs of kidney disease. Adults have a greater risk of developing chronic kidney disease.

• #35 Vasculitis, Blood Vessel Inflammation | TGH

  https://www.tgh.org/institutes-and-services/conditions/vasculitis

  Inflammation of the blood vessels in the kidneys (renal vasculitis) can impair their ability to filter blood effectively, leading to fluid retention and increased blood volume, both of which can raise blood pressure. […] Vasculitis can cause swelling and narrowing in the small blood vessels that supply nerves, reducing blood flow. The resulting lack of oxygen and nutrients can lead to nerve dysfunction or damage. […] Many people with vasculitis experience long-term fatigue from both the condition and its treatment. […] If vasculitis affects blood vessels in the eyes, it can lead to vision impairment or blindness. […] Ongoing inflammation can cause blood vessels to scar and narrow, reducing blood flow to vital organs and tissues.

• #36 ANCA Vasculitis | UNC Kidney Center

  https://unckidneycenter.org/kidneyhealthlibrary/glomerular-disease/anca-vasculitis/

  The inflammation in the kidneys from the antibodies (ANCAs) attacking the glomeruli (filters) also causes the kidney function to get worse, which means that the kidneys are not able to clean the blood by getting rid of toxins/waste, fluid, and electrolytes in the urine. This can lead to kidney failure. […] Sometimes ANCA vasculitis can affect kidney function slowly- over weeks, months, or even years- but in many people, it can happen very quickly, in days. The inflammation leads to scarring, or permanent damage to the kidney. Treatment can decrease the inflammation and swelling. This is why it is usually important to treat ANCA glomerulonephritis (kidney disease from ANCA vasculitis) quickly, to try to prevent or decrease the amount of damage and scarring in the kidney.

• #37 Pain Management: Vasculitis

  https://www.webmd.com/pain-management/vasculitis-cause

  Vasculitis can be very serious. […] An enormous number of vasculitis symptoms are possible because any organ system may be involved. […] Vasculitis in the brain may cause a stroke or, in the heart, may result in a heart attack. […] Inflammation in the kidney could result in abnormalities noted on urine tests and can lead to progressive kidney failure. […] Sometimes, the symptoms may be as general as fever, loss of appetite, weight loss, and loss of energy. […] The outlook depends on the type of vasculitis. […] Today, regular life spans are possible with proper treatment. […] The success of treatment is related to prompt diagnosis, aggressive treatment, and careful follow-up.

• #38 Vasculitis and Lupus | Lupus Foundation of America

  https://www.lupus.org/resources/vasculitis-and-lupus

  Vasculitis can affect the smallest blood vessels (capillaries) to the largest blood vessels (arteries and veins). General symptoms include: […] Vasculitis can cause many more specific symptoms based on where in the body the inflammation is. […] Symptoms of vasculitis in the brain range from mild to severe symptoms. They can include: […] Vasculitis can keep the intestines from getting enough blood flow. Symptoms may include: […] Its possible to have vasculitis in your coronary arteries (the tubes bring blood to your heart), but its rare. When it does happen, it can cause a feeling of heaviness in the chest, chest pain, shortness of breath especially during physical activity. […] In the lungs, vasculitis can cause symptoms like fever and cough. […] Rarely, vasculitis can lead to scarring of the lungs. This can cause chronic (long-term) shortness of breath. […] For some people, vasculitis in the eyes causes sudden blurry vision, which may lead to some vision loss. Others have no symptoms at all.

• #39 Vasculitis, Blood Vessel Inflammation | TGH

  https://www.tgh.org/institutes-and-services/conditions/vasculitis

  Vasculitis can cause a variety of symptoms based on the condition type and organs involved. General warning signs can include fever, fatigue, unexplained weight loss and general aches and pains, which may be accompanied by specific symptoms affecting the: […] Rashes and discoloration […] Pain and swelling […] Coughing and shortness of breath […] Dark or bloody urine […] Numbness and tingling, especially in the hands and feet. […] Chronic inflammation can damage organs and other structures throughout the body, such as the kidneys, lungs, heart and nervous system, potentially resulting in long-term dysfunction. […] Swelling from inflammation may narrow blood vessels, slowing the flow of blood and encouraging clot formation, which in turn can increase the risk of heart attack, stroke and deep vein thrombosis (DVT).

• #40 Managing Symptoms & Side Effects – Vasculitis Foundation

  https://vasculitisfoundation.org/pediatrics-vasculitis/managing-symptoms-side-effects/

  People with vasculitis often look healthy on the outside, but internally, their bodies are fighting hard to heal. You may feel pain, weakness, and extreme fatigue. […] It is normal to feel fatigued when living with vasculitis. Fatigue often begins before diagnosis and may persist even during or after treatment. […] Fatigue can be related to anemia and other laboratory changes seen in vasculitis. Specific organ involvement such as kidney, brain or lung disease can also cause fatigue. […] It is important to understand that people with vasculitis need more sleep than usual to allow their body to heal. […] Anxiety and depression can often accompany a diagnosis of vasculitis. […] Some aspects of anxiety may appear while living with vasculitis. […] Prednisone specifically can intensify the feelings of depression.

• #41 Vasculitis Types, Causes, Symptoms, Diagnosis, Treatment

  https://www.medicinenet.com/vasculitis/article.htm

  Symptoms of vasculitis depend upon the organs that are involved and the severity of the condition. […] Vasculitis may cause symptoms involving the whole body like fatigue, malaise, weakness, and weight loss. […] Specific organ complaints may include the following: Skin: Rashes, skin discoloration, and ulcers; Muscles: Muscle pain and tenderness; Lung: Shortness of breath and cough; Heart: Congestive heart failure; Brain: Headaches, confusion, seizures, stroke, paralysis, numbness, and lightheadedness; Kidney: Kidney failure. […] Vasculitis involves a wide spectrum of diseases and involves many organ systems. The prognosis for vasculitis as a whole is uncertain and depends upon the type of vasculitis present. Some diseases are aggressive while others can be controlled with medications.

• #42 Vasculitis Guide: Causes, Symptoms and Treatment Options

  https://www.drugs.com/health-guide/vasculitis.html

  Takayasu’s arteritis– Malaise, fever, night sweats, joint pain, poor appetite, weight loss, pain in one or both arms, fainting, symptoms of congestive heart failure (such as shortness of breath that’s worse lying down) […] Kawasaki disease– Swollen lymph nodes (swollen glands) in the neck; swelling in the skin; redness of the mouth, lips, and palms; peeling skin at the fingertips; chest pain. […] How long vasculitis lasts depends on the type. For example, most cases of cutaneous leukocytoclastic angiitis or Kawasaki disease go away on their own over a period of days or weeks. Granulomatosis with polyangiitis may respond to treatment at first, but many patients relapse and require treatment again. Giant cell arteritis typically requires therapy for a year or more. […] The outlook depends on the specific type of vasculitis:

• #43 Vasculitis Guide: Causes, Symptoms and Treatment Options

  https://www.drugs.com/health-guide/vasculitis.html

  Polyarteritis nodosa– Though previously a disease with a high mortality, it is now treated successfully in up to 90% of patients. […] Granulomatosis with polyangiitis– At one time, this illness was also almost always fatal. Now, with proper treatment, 90% of people have significant relief of symptoms, and the disease goes away completely in about 60% of patients. […] Takayasu’s arteritis– For mild cases, the long-term prognosis is good. Overall, the five-year survival is about 80% to 90%.

• #44 Vasculitis Types & Symptoms | The University of Kansas Health System

  https://www.kansashealthsystem.com/care/conditions/vasculitis

  Vasculitis is an uncommon autoimmune disease that causes inflammation of the blood vessels. Arteries, veins and capillaries can all be affected by vasculitis, and the symptoms can range from mild to life-threatening. Early detection and treatment of vasculitis symptoms is critical to prevent long-term damage. […] The symptoms of vasculitis vary depending on the location of the blood vessels affected as well as the progression of the disease. General signs that are associated with vasculitis include: […] However, depending on the specific organs that are impacted by vasculitis, you may notice additional symptoms: […] Risk factors for vasculitis vary depending on whether the condition is primary or secondary, but can include a family history of vasculitis, the presence of an autoimmune disorder like rheumatoid arthritis, a history of blood cancer or a history of hepatitis. Vasculitis can also occur as a reaction to certain medications. […] Your doctor may also perform these tests through the course of your treatment to see whether your vasculitis symptoms show signs of improvement.

• #45 Vasculitis Signs & Symptoms | Rush

  https://www.rush.edu/conditions/vasculitis

  Vasculitis can affect any body system and can have a wide range of symptoms. For most types, symptoms can include the following: Fever, Weight loss, Fatigue (tiredness), Aches and pains. […] Diagnosis of vasculitis can be tricky since symptoms can emerge over time. […] Your prognosis depends on various factors: The type of vasculitis you have, Which of your organs are affected, The severity of your symptoms, How quickly your condition worsens. […] Vasculitis is treatable, but it is not curable. Your prognosis depends on various factors: The type of vasculitis you have, Which of your organs are affected, The severity of your symptoms, How quickly your condition worsens.

• #46 Managing Symptoms & Side Effects – Vasculitis Foundation

  https://vasculitisfoundation.org/pediatrics-vasculitis/managing-symptoms-side-effects/

  You may have concerns about how the vasculitis will affect your daily life (school, sports, socializing with friends) and your future plans. […] It is important to know that there are numerous support systems available to help you to help yourself in order to feel more in control of your life. […] After the diagnosis of a chronic or life-threatening illness, it’s quite common for there to be stress. Patients often don’t have a clear explanation for what’s going on in their bodies, there’s a lack of information, and a complex medical system to navigate, which can cause a lot of uncertainty.

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