Materiały źródłowe

• #1 Hashimoto’s disease – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hashimotos-disease/symptoms-causes/syc-20351855

  Hashimoto’s disease is an autoimmune disorder. The immune system creates antibodies that attack thyroid cells as if they were bacteria, viruses or some other foreign body. The immune system wrongly enlists disease-fighting agents that damage cells and lead to cell death. […] What causes the immune system to attack thyroid cells is not clear. The onset of disease may be related to: genetic factors, environmental triggers, such as infection, stress or radiation exposure, interactions between environmental and genetic factors.

• #2 Hashimoto Thyroiditis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459262/

  Hashimoto thyroiditis, also known as chronic autoimmune thyroiditis or chronic lymphocytic thyroiditis, is an autoimmune disease that leads to the destruction of thyroid follicular cells through immune-mediated processes. […] The underlying etiology of Hashimoto thyroiditis is still not fully understood but is thought to be a combination of genetic and environmental factors. […] Hashimoto thyroiditis has been shown to have a strong familial predisposition with disease clustering in families, including some members developing Graves disease. […] Several genes, including those encoded by the human leukocyte antigen (HLA) complex, immune regulatory genes (CD40, FoxP3, CD25, CTLA-4, and PTPN22), and thyroid-specific genes (TSH receptor and thyroglobulin), are linked to the development of Hashimoto thyroiditis.

• #3 Hashimoto’s Disease: What It Is, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/17665-hashimotos-disease

  Hashimotos disease is an autoimmune disease, which means your bodys immune system attacks your cells and organs. […] Your immune system makes antibodies that attack your thyroid tissue for unknown reasons. […] Large numbers of white blood cells (specifically, lymphocytes), build up in your thyroid. […] This buildup causes inflammation (thyroiditis) and damages your thyroid. […] Over time, the damage can prevent your thyroid from making enough thyroid hormone that your body needs. […] Hashimotos disease is the most common cause of hypothyroidism in countries with widely available iodized salt and other iodine-enriched foods. […] Iodine deficiency is the most common cause in other countries. […] Factors that may increase your risk of developing Hashimotos disease include your family history: Research suggests that your genetics account for about 80% of your likelihood of developing Hashimotos. […] If you have biological family members with Hashimotos disease or other thyroid diseases, youre more likely to develop it. […] Youre also more likely to get Hashimotos if you have other autoimmune conditions.

• #4

  https://healthmatch.io/hashimotos-disease/what-causes-hashimotos-disease

  Hashimotos disease is an autoimmune disorder that occurs when your immune system attacks your thyroid, causing it to produce too little thyroid hormone. […] The exact cause of Hashimotos disease is poorly understood. Most people with the condition develop thyroid antigens which cause the body to attack the thyroid. Up to 15% of people never develop these antibodies, despite having clinical symptoms. […] Researchers think theres a link between Hashimotos and other autoimmune disorders, including pernicious anemia, celiac disease, Graves disease, rheumatoid arthritis, and multiple sclerosis. […] Several other factors may put you at increased risk of developing Hashimotos. Research suggests that around 80% of Hashimotos cases are caused by genetic factors, with an additional 20% caused by environmental factors.

• #5 Hashimoto’s thyroiditis – Wikipedia

  https://en.wikipedia.org/wiki/Hashimoto%27s_thyroiditis

  Hashimoto’s thyroiditis is thought to be due to a combination of genetic and environmental factors. […] The causes of Hashimoto’s thyroiditis are complex. Around 80% of the risk of developing an autoimmune thyroid disorder is due to genetic factors, while the remaining 20% is related to environmental factors (such as iodine, drugs, infection, stress, radiation). […] Thyroid autoimmunity can be familial. Many patients report a family history of autoimmune thyroiditis or Graves’ disease. […] The strong genetic component is borne out in studies on monozygotic twins, with a concordance of 38-55%, with an even higher concordance of circulating thyroid antibodies not in relation to clinical presentation (up to 80% in monozygotic twins). […] The incidence of autoimmune thyroid disorders is increased in people with chromosomal disorders, including Turner, Down, and Klinefelter syndromes.

• #6 Hashimoto’s disease: MedlinePlus GeneticsLock

  https://medlineplus.gov/genetics/condition/hashimotos-disease/

  Variations in several genes have been studied as possible risk factors for Hashimoto’s disease. Some of these genes are part of a family called the human leukocyte antigen (HLA) complex. The HLA complex helps the immune system distinguish the body’s own proteins from proteins made by foreign invaders (such as viruses and bacteria). Other genes that have been associated with Hashimoto’s disease help regulate the immune system or are involved in normal thyroid function. Most of the genetic variations that have been discovered are thought to have a small impact on a person’s overall risk of developing this condition. […] Other, nongenetic factors also play a role in Hashimoto’s disease. These factors may trigger the condition in people who are at risk, although the mechanism is unclear. Potential triggers include changes in sex hormones (particularly in women), viral infections, certain medications, exposure to ionizing radiation, eating large amounts of foods that contain animal proteins, and excess consumption of iodine (a substance involved in thyroid hormone production).

• #7 Hashimoto’s thyroiditis – Wikipedia

  https://en.wikipedia.org/wiki/Hashimoto%27s_thyroiditis

  Specific HLA alleles have a higher affinity to auto-antigenic thyroidal peptides and can contribute to autoimmune thyroid disease development. […] CTLA-4 is the second major immune-regulatory gene related to autoimmune thyroid disease. […] PTPN22 is the most recently identified immune-regulatory gene associated with autoimmune thyroid disease. […] Both excessive and insufficient iodine intake has been implicated in developing antithyroid antibodies. […] Comorbid autoimmune diseases are a risk factor for developing Hashimoto’s thyroiditis, and the opposite is also true. […] Other environmental factors include selenium deficiency, infectious diseases such as hepatitis C, rubella, and possibly Covid-19, toxins, dietary factors, radiation exposure, and gut dysbiosis.

• #8 Hashimoto’s Disease: Causes and Risk Factors

  https://www.verywellhealth.com/hashimotos-disease-causes-and-risk-factors-4571020

  Genetics, autoimmune diseases, and being female increase your risk […] Researchers dont know why this happens, but they think genetics might be to blame and risk is higher for people with a family history of autoimmune and thyroid conditions. […] There are several inherited genes associated with Hashimotos disease, but the two most common are HLA-DR3 and HLA-DR5. […] Having another autoimmune disease is a risk factor for developing Hashimotos disease. […] Hashimotos disease predominately affects more women than men. […] The chances of developing Hashimotos disease increase with age. […] Excessive iodine has been speculated to trigger Hashimotos disease and other types of thyroid disease. […] Research has found a link between exposure to radiation and Hashimotos disease. […] It is difficult to determine which risk factors will put a person at the greatest risk for Hashimotos disease. Genetics are the highest risk factors but often, the disease is caused by factors a person cannot prevent.

• #9 Hashimoto Thyroiditis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459262/

  Since only 50% of the monozygotic twins in a Danish study were shown to have concordance for Hashimoto thyroiditis, environmental factors seem to have an essential role in the development of Hashimoto thyroiditis. […] Similar to many allergic and autoimmune conditions, individuals living in a more hygienic environment with less exposure to microbial agents seem to have a higher incidence of Hashimoto thyroiditis. […] Mild iodine deficiency has been associated with a lower prevalence of Hashimoto thyroiditis, whereas chronic exposure to excess iodine intake has been associated with a higher prevalence of Hashimoto thyroiditis. […] Selenoproteins are essential for thyroid function and protection. […] Deficiency in this mineral has been associated with a higher risk of Hashimoto thyroiditis.

• #10 What Causes Hashimoto’s Thyroiditis? – Nikolas Hedberg, DC, DABCI, DACBN

  https://drhedberg.com/causes-hashimotos-thyroiditis/

  In Hashimoto’s Disease, Thyroid […] So Hashimotos thyroid disease is the most common autoimmune disease in the world. […] So the Epstein-Barr virus is probably the most common infection that causes Hashimotos thyroid disease. […] So if you have Hashimotos, the first thing you want to get tested for is Epstein-Barr virus and thats done with a blood test. […] But there is some research out there that shows that when iodine is added to the food supply in certain populations, like in Denmark and Turkey as examples, the incidence of Hashimotos thyroiditis did increase significantly when iodine was added to the food supply. […] The other thing we know is that some research out of Japan shows that if you give someone iodine who has Hashimotos thyroiditis, you increase whats called lymphocytic infiltration into the thyroid gland.

• #11 Hashimoto Thyroiditis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459262/

  Thyroid peroxidase is an enzyme that contains heme (iron). Hence, the presence of iron deficiency can impair thyroid activity and also increase thyroid autoimmunity. […] Vitamin D has been established as an important immunomodulator. […] The gut microbiota regulates the immune system and contributes significantly to thyroid hormone metabolism. Hence, alterations in the gut microbiome can increase the risk of thyroid autoimmunity.

• #12 Hashimoto Thyroiditis: Practice Essentials, Background, Etiology

  https://emedicine.medscape.com/article/120937-overview

  The development of Hashimoto thyroiditis may be influenced not only by inherent predisposition but also by environmental factors. […] Insufficient dietary intake of selenium may lead to worsening of the condition. […] Emerging anticancer medications, including interferon-alpha and tyrosine kinase inhibitors, have been linked to the onset of Hashimoto thyroiditis. […] A study by Mazokopakis et al indicated that an association may exist between vitamin D deficiency and the development of Hashimoto thyroiditis.

• #13 What Causes Hashimoto’s Thyroiditis | Pompa Program

  https://pompaprogram.com/what-causes-hashimotos-thyroiditis/

  Exactly what causes Hashimoto’s thyroiditis is unknown, although genetics, the microbiome, and environmental factors are all responsible, as is the case with many autoimmune disorders. […] Environmental factors also contribute to the development of Hashimoto’s thyroiditis. Exposure to certain toxins and pollutants, such as heavy metals, can damage the thyroid gland and potentially trigger an autoimmune response. […] One of the most important causes of Hashimoto’s thyroiditis is a selenium deficiency. Selenium is a trace mineral that plays an essential role in thyroid health and metabolism. […] Vitamin D plays an important role in the management of Hashimoto’s thyroiditis, as Vitamin D deficiency is linked to an increased risk and severity of the autoimmune condition. […] Iron deficiency anemia has been associated with Hashimoto’s thyroiditis. Iron is necessary for the production of thyroid hormones. […] Studies have concluded that there is a connection between the composition of microorganisms within the gut and Hashimoto’s Thyroiditis development. Some theories suggest that an imbalance in the gut microbiome could lead to inflammation and autoimmunity, which can cause Hashimoto’s Thyroiditis.

• #14 PharmToTable | Underlying causes of Hashimoto’s thyroiditis

  https://pharmtotable.life/2022/01/10/underlying-causes-of-hashimotos-thyroiditis/

  Hashimotos thyroiditis, an autoimmune condition, involves chronic inflammation of the thyroid gland due to attack by the bodys own immune system. […] There are certain environmental factors that can trigger or underlie the development of Hashimotos. […] The gut houses the majority of our immune system so its no wonder that increased intestinal permeability (aka leaky gut) is a common factor in autoimmune disease. […] Autoimmune diseases in general are linked to various infections, and there are numerous bacteria, viruses, and parasites that have been linked to the development of Hashimotos thyroiditis. […] There are over 80,000 chemicals registered for use in the United States, with an estimated 2,000 new ones added each year. […] Chronic inflammation is a hallmark characteristic of most chronic disease and autoimmune disorders that are prevalent today.

• #15 Hashimoto’s Thyroiditis: Symptoms, Causes, and Treatment

  https://www.webmd.com/women/hashimotos-thyroiditis-symptoms-causes-treatments

  Also called Hashimoto’s disease, Hashimoto’s thyroiditis is an autoimmune disease, a disorder in which the body’s immune system attacks healthy or normal cells. In people with Hashimoto’s, the immune system attacks the thyroid. […] The exact cause of Hashimoto’s is not known, but many factors are believed to play a role. They include: […] People who get Hashimoto’s often have family members who have thyroid disease or other autoimmune diseases. This suggests genes may play a role in who gets the disease. […] A virus or bacteria may cause the immune system to attack itself. […] Factors like stress or excessive radiation may play a role. […] Having an autoimmune disease, like rheumatoid arthritis, lupus, or type 1 diabetes, increases your risk of getting Hashimoto’s. […] Research suggests certain drugs and too much iodine, a trace element required by your body to make thyroid hormones, may trigger thyroid disease in susceptible people. […] Increased cases of thyroid disease have been reported in people exposed to radiation, including the atomic bombs in Japan, the Chernobyl nuclear accident, and radiation treatment for a form of blood cancer called Hodgkin’s disease.

• #16 What Causes Hashimoto’s Thyroiditis? – Nikolas Hedberg, DC, DABCI, DACBN

  https://drhedberg.com/causes-hashimotos-thyroiditis/

  Yersinia enterocolitica you can get just from contaminated food or water and it gets into the gut. […] So by treating the Yersinia, you can remove the reason why the immune system is overactive and attacking the thyroid gland. […] Post partum, that means after giving birth many women will develop Hashimotos thyroiditis after they give birth. […] And there is some research that connects Hashimotos thyroiditis with Lyme disease. […] So Helicobacter pylori is, again, one of the big three, and well test that in most people with Hashimotos. […] So again, the big three are really the Epstein Barr virus, Yersinia enterocolitica, and H. pylori. […] Excess estrogen, so one of the things we know is that if you have too much estrogen in your body, this can actually inhibit your bodys ability to control the Epstein Barr virus.

• #17 Hashimoto’s Disease – NIDDK

  https://www.niddk.nih.gov/health-information/endocrine-diseases/hashimotos-disease

  Hashimotos disease is an autoimmune disorder that can cause hypothyroidism, or underactive thyroid. […] Researchers dont know why some people develop Hashimotos disease, but a family history of thyroid disease is common. Several factors may play a role, including genes and viruses, such as hepatitis C. […] Hypothyroidism can also be caused by some medicines used to treat bipolar disorder or other mental health problems, iodine-containing medicines used to treat abnormal heart rhythm, and exposure to toxins, such as nuclear radiation.

• #18 Hashimoto’s thyroiditis | Hashimoto’s disease – Symptoms & Causes PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact

  https://www.pacehospital.com/hashimoto-s-thyroiditis-hashimotos-disease

  Hashimoto’s disease is an autoimmune disorder (the immune system makes antibodies that turn against the body’s own tissues), which can cause hypothyroidism or an underactive thyroid. […] The exact cause of Hashimoto disease (autoimmune thyroiditis) is still under research, and the following might be the possible contributors: […] Genes: The presence of Hashimoto disease or other autoimmune diseases in the family history may increase the likelihood of disease occurrence. […] Viral infections: According to research, viral infections such as hepatitis C (which attacks the liver and causes inflammation) have autoimmune phenomena, which include rheumatoid arthritis, thyroid disease, cryoglobulinaemia, immune thrombocytopenic purpura, systemic lupus erythematous, and Sjogren syndrome. […] Usage of certain medications: Medications that are used to treat bipolar disorder, other mental health problems, and abnormal heart rhythms have the potential to cause Hashimoto disease.

• #19 Potential Root Causes of Thyroid Dysfunction | Paloma Health

  https://www.palomahealth.com/learn/root-causes-thyroid-dysfunction?srsltid=AfmBOoobNSO_5vh4TGZE992lRje3wsH00B73jb4eVrrTnS1_HwhpLmKp

  Furthermore, those living with post-traumatic stress disorder (PTSD) are at a higher risk of developing Hashimotos than those without PTSD. […] More recently, COVID-19 has also been linked to thyroid gland dysfunction and disorders. […] Experts believe that the inflammatory process and oxidative stress from the COVID-19 infection trigger an overactive immune system, resulting in an underactive thyroid gland. But more research is needed to understand the link between COVID-19 and Hashimotos.

• #20 Hashimoto’s Thyroiditis Causes and Risk Factors | Risk of getting Hashimoto’s disease

  https://www.patientsengage.com/conditions/hashimotos-thyroiditis/causes-risk-factors

  Radiation exposure has been shown to bring on autoimmune thyroid disease. This includes radiation from the atomic bomb in Japan, the nuclear accident at Chernobyl, and radiation treatment of Hodgkins disease (a type of blood cancer). […] Other autoimmune diseases such as: Vitiligo, a disease that destroys cells and leads to patchy loss of skin pigmentation; Rheumatoid arthritis, a disease that affects the lining of the joints throughout the body causing painful swelling, which ultimately results in bone erosion and joint deformity; Addisons disease, which affects the adrenal glands that make hormones that help your body respond to stress and regulate your blood pressure and water and salt balance; Type 1 diabetes, which causes blood sugar levels to be too high; Graves disease, which causes the thyroid to make too much thyroid hormone (hyperthyroidism); Pernicious anaemia, which keeps your body from absorbing vitamin B12 and making enough healthy red blood cells; Lupus, which damages many parts of the body, such as the joints, skin, blood vessels, and other organs.

• #21 Hashimoto’s Thyroiditis Causes and Risk Factors | Risk of getting Hashimoto’s disease

  https://www.patientsengage.com/conditions/hashimotos-thyroiditis/causes-risk-factors

  Hashimotos thyroiditis, also called Hashimotos disease, is an autoimmune disease in which the thyroid is attacked by the bodys immune system, causing symptoms of hypothyroidism (underactive thyroid gland). It is most common among middle-aged women. […] Many factors are thought to play a role in causing Hashimotos disease. These include: […] Genes: Family members may have Hashimotos disease or other autoimmune diseases. […] Gender: Hashimotos thyroiditis is 7 times more common in women than men. […] Pregnancy affects the thyroid. Some women have thyroid problems after having a baby, which usually go away. But about 20 percent of these women develop Hashimotos thyroiditis in later years. This suggests that pregnancy might trigger thyroid disease in some women. […] Too much iodine and some drugs like amiodarone (for treating heart rhythms), methemazole (antithyroid drugs), interferon-alpha (drugs used in treating cancer) may trigger the onset of thyroid disease in people who are prone to it.

• #22 Hashimoto’s Syndrome Symptoms, Causes & Treatments | CentreSpring MD

  https://centrespringmd.com/hashimotos-syndrome-symptoms-causes-treatments/?srsltid=AfmBOoqyP4YRQbHbUiwwL4PEeKAnq6dDDLnfgZWn2xXvt9qmVdRgUI4i

  Hashimoto’s syndrome affects as many as 7-8X more women than men, which suggests that sex hormones may play a role in its occurrence. […] While the syndrome can occur even in teenage years or early adulthood, it more commonly occurs in middle-aged patients. […] Radiation Exposure. Individuals who have been exposed to excessive levels of radiation may be at increased risk of Hashimoto’s syndrome.

• #23 Hashimoto’s thyroiditis: Symptoms, causes, and diagnosis

  https://www.medicalnewstoday.com/articles/266780

  Hashimotos thyroiditis, or Hashimotos disease, is an autoimmune condition in which the immune system attacks the thyroid gland. […] Hashimotos thyroiditis is not it is an autoimmune disease. […] The reasons for this are unclear, but genetic factors appear to play a role. […] However, even taking genetics into account, a person may not develop hypothyroidism unless they are exposed to a trigger, such as: stress, pregnancy, infection. […] Also, people who consume too much or too little iodine may be more susceptible to thyroiditis.

• #24 Hashimoto’s disease

  https://womenshealth.gov/a-z-topics/hashimotos-disease

  Hashimoto’s disease, or Hashimoto’s thyroiditis, is an autoimmune disease that damages the thyroid gland. […] In people with Hashimoto’s disease, the immune system makes antibodies that attack the thyroid gland. This damages your thyroid gland, so it does not make enough thyroid hormone. Hashimoto’s disease often leads to hypothyroidism. […] Researchers aren’t sure exactly what causes Hashimoto’s disease. Studies show that it is more common in women than men. […] Hashimoto’s disease may run in families. Researchers are working to find the gene or genes involved. […] Some women have thyroid problems after having a baby, called postpartum thyroiditis. […] If left untreated, hypothyroidism from Hashimoto’s disease can cause other health problems, including infertility, miscarriage, giving birth to a baby with birth defects, and high cholesterol. […] Untreated or poorly treated hypothyroidism can lead to problems during pregnancy, such as preeclampsia, anemia, miscarriage, placental abruption, and postpartum bleeding. […] Some women develop thyroid problems in the first year after giving birth. This is called postpartum thyroiditis.

• #25 Understanding Hashimoto’s Thyroiditis: Symptoms, Causes

  https://medicalweightlossutah.com/hashimotos-thyroiditis-symptoms-causes/

  Hashimotos Thyroiditis is a complex condition with a multifaceted origin. While the exact cause remains elusive, several factors that increase the risk of developing this autoimmune disorder have been identified. […] Individuals with a family history of Hashimotos or other autoimmune diseases are at a higher risk. […] Women are more frequently affected than men, suggesting a potential link with hormonal factors. Events like pregnancy or menopause can also trigger the onset in predisposed individuals. […] Certain viruses are believed to trigger Hashimotos in people with a genetic predisposition. […] Individuals exposed to excessive environmental radiation levels are at a heightened risk. […] People with conditions like type 1 diabetes, lupus, or rheumatoid arthritis might have an increased risk of developing Hashimotos. […] While it can occur at any age, its most commonly diagnosed in middle age. […] Women are up to 10 times more likely to develop Hashimotos than men.

• #26 Root Cause Approach & Hashimoto’s – Dr. Izabella Wentz

  https://thyroidpharmacist.com/articles/root-cause-approach-and-hashimotos/

  If we can break the cycle of autoimmunity by removing the two legs of the three-legged stool that we can change, we can fix the leaky bucket. […] While there is a very long list of potential triggers that can cause intestinal permeability, the most common triggers that cause leaky gut are food sensitivities, nutrient deficiencies, a deficiency in digestive enzymes, an imbalance of gut bacteria, and intestinal infections. […] Addressing these food sensitivities, nutrient and digestive enzyme deficiencies, and intestinal infections, can help to address the leaky gut and reverse the condition. […] In my clinical practice, I have also often found infections to be a primary root cause for Hashimotos. […] Stress is another common trigger. […] Remember, triggers are one of the legs of the three-legged stool for autoimmunity. […] Hashimoto’s is very much an individual condition. […] You will have to dig down to why the immune system is imbalanced in the first place and this will tell you how you begin to finally feel better, reduce your thyroid antibodies and even take your condition into remission.

• #27 PharmToTable | Underlying causes of Hashimoto’s thyroiditis

  https://pharmtotable.life/2022/01/10/underlying-causes-of-hashimotos-thyroiditis/

  Having autoimmune thyroid disease (AITD) puts an individual at risk of developing other autoimmune disorders. […] Working with a functional medicine provider to address the factors mentioned above can help prevent further damage to the thyroid, restore function, minimize symptoms and even put autoimmune disease into remission for some.

• #28 Hashimoto’s Disease | University of Michigan Health

  https://www.uofmhealth.org/conditions-treatments/endocrinology-diabetes-and-metabolism/hashimotos-disease

  Hashimoto’s thyroiditis, also called Hashimoto’s disease, chronic autoimmune thyroiditis, or chronic lymphocytic thyroiditis, is an autoimmune disease. […] The disorder causes the body’s immune system to produce antibodies that attack thyroid tissue and eventually destroy the thyroid gland, leading to hypothyroidism, or the underproduction of thyroid hormone. […] Hashimoto’s thyroiditis is associated with other conditions, including diabetes, Addison’s disease, rheumatoid arthritis, pernicious anemia, and premature menopause. […] Although Hashimoto’s thyroiditis most commonly causes hypothyroidism, in some cases, it will first cause enlargement of the thyroid gland (goiter) and temporary thyroid gland overactivity (hyperthyroidism). This is called hashitoxicosis, and it is almost always followed by development of hypothyroidism.

• #29 What Is Hashimoto’s Thyroiditis? Symptoms, Causes, Diagnosis, Treatment, and Prevention

  https://www.everydayhealth.com/hashimotos-thyroiditis/guide/

  The disease is more common in women than in men it occurs at least eight times more often in women than men, according to the National Institute of Diabetes and Digestive and Kidney Diseases. […] Youre more likely to develop Hashimotos thyroiditis if other people in your family have it. […] Those with Hashimotos thyroiditis may be more likely to also have: Autoimmune hepatitis, Addisons disease, Celiac disease, Lupus, Rheumatoid arthritis, Pernicious anemia, Type 1 diabetes, Vitiligo, Sjgrens syndrome.

• #30 Chronic thyroiditis (Hashimoto disease) Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/diseases-conditions/chronic-thyroiditis-hashimoto-disease

  Chronic thyroiditis is caused by a reaction of the immune system against the thyroid gland. It often results in reduced thyroid function (hypothyroidism). […] Hashimoto disease is a common thyroid gland disorder. It can occur at any age, but is most often seen in middle-aged women. It is caused by a reaction of the immune system against the thyroid gland. […] In rare cases, the disease may be related to other hormone problems caused by the immune system. It can occur with poor adrenal function and type 1 diabetes. In these cases, the condition is called type 2 polyglandular autoimmune syndrome (PGA II). […] Rarely (usually in children), Hashimoto disease occurs as part of a condition called type 1 polyglandular autoimmune syndrome (PGA I), along with: Poor function of the adrenal glands, Fungal infections of the mouth and nails, Underactive parathyroid gland.

• #31 10 Common Causes of Hypothyroidism You Need to Know

  https://www.everydayhealth.com/thyroid-conditions/hypothyroidism/hashimotos-thyroiditis-plus-other-causes-hypothyroidism/

  Certain medications could cause hypothyroidism. The most common of these is lithium. Other possibilities include amiodarone (Pacerone) and some chemotherapy drugs. You may be more at risk for medication-induced hypothyroidism if you already have a genetic predisposition to autoimmune diseases. […] Radiation therapy around the head or neck area can inadvertently damage your thyroid gland and lead to hypothyroidism. […] A lack of iodine is a common cause of hypothyroidism in developing countries it may also lead to a goiter (enlarged thyroid gland) in such cases.

• #32

  https://healthmatch.io/hashimotos-disease/what-causes-hashimotos-disease

  Researchers believe almost everyone with Hashimotos has a genetic predisposition to the disease, but some environmental factors can trigger it. […] Environmental triggers thought to contribute to the development of Hashimotos disease include: Consuming too much iodine increases your chance of developing Hashimotos disease. […] Certain viruses may cause Hashimotos disease, such as mumps, Epstein-Barr, and possibly even COVID-19. […] Several heavy metals and carcinogenic chemicals have been shown to increase your risk of developing Hashimotos disease. […] Many people with Hashimotos disease are deficient in vitamin D. Researchers believe too little vitamin D may trigger Hashimotos, but a link between the two hasnt yet been proven. […] Cytotoxic chemotherapy treatments (e.g., R-CHOP, ICE, DHAP, and FOLFOX) used to treat a variety of cancers can damage the thyroid and increase your risk of Hashimotos disease. […] Genetics and environmental factors can increase your risk of developing Hashimotos disease. Genetic risks include gender, age, and ethnicity, while environmental factors include toxins, vitamin D levels, diseases, iodine intake, and certain medications.

• #33 Why Did I Get Hashimoto’s Hypothyroidism? 9 Causes | RedRiver

  https://www.redriverhealthandwellness.com/why-did-i-get-hashimotos-nine-things-that-can-trigger-autoimmune-hashimotos-hypothyroidism/

  Certain foods can cause an immune reaction in some people. In other words, eating those foods triggers inflammation throughout the body and often leads to leaky gut. The most common food intolerance to trigger Hashimotos is gluten, the protein found in wheat, rye, barley, and spelt. […] BPA, the chemical found in plastics, store receipts, and plastic water and soda bottles has been linked with thyroid autoimmunity. […] High blood sugar is very inflammatory and damages tissue in the body, the gut, and the brain. […] Healthy immune function depends on appropriate levels of hormones and hormone activity to avoid over zealous and inflammatory, thus raising the risk of autoimmunity. […] A woman who goes into pregnancy with immune and metabolic imbalances is at more risk for these periods triggering an autoimmune disease such as Hashimotos. […] While infections may not be the sole cause of autoimmunity, researchers have identified infections directly related to triggering hypothyroidism. […] Chronic stress is the most potent threat to your immune balance and Hashimotos hypothyroidism condition.

• #34 Reverse Hashimoto’s Disease by Addressing These Nine Underlying Triggers: A Functional Medicine Approach – Caplan Health Institute

  https://caplanhealthinstitute.com/reverse-hashimotos-disease-by-addressing-these-nine-underlying-triggers-a-functional-medicine-approach/

  Hashimotos disease, a form of autoimmune hypothyroidism, is a condition that causes an underactive thyroid. When someone has Hashimotos, their immune system makes antibodies that attack the thyroid gland. The thyroid then doesn’t produce enough thyroid hormones, which results in hypothyroidism. […] Untreated Hashimotos can lead to health issues including goiters, cardiovascular risks, mental health issues, myxedema, and birth defects. […] Hashimotos disease can be reversed once these areas of health are addressed. […] Environmental exposures are often overlooked by conventional medicine as a contributor to autoimmune thyroid disease, but they have been shown to impact a variety of health conditions. […] Having celiac disease can increase your risk of Hashimotos. […] Chronic stress can lead to adrenal fatigue, which in turn leads to chronic inflammation and immune upregulation. […] Food sensitivities can aggravate Hashimotos disease. […] Insulin surges counteract high blood sugar but they ramp up inflammation and irritate the immune system. […] Hormones are the chemicals that tell our cells what to do and imbalances lead to the wrong signals.

• #35 THE ROOT CAUSES OF AUTOIMMUNE THYROID/HASHIMOTO’S

  https://www.advancedintegratedhealth.com/what-are-the-root-causes-of-autoimmune-thyroid-hashimotos/

  Inflammation is the cause of ALL chronic, degenerative disease. When the body attacks itself, INFLAMMATION results because the best definition of INFLAMMATION is simply The bodys response to an injury. Hashimotos raises your risk of neurogenerative diseases, such as Parkinsons and may be responsible for cognitive decline. […] A main UNDERLYING CAUSE for virtually ALL autoimmune disorders is a broken gut, and uncontrolled Hashimotos also attacks the gut lining, worsening the problem. […] The first is STRESS. […] Major life events can have a dramatic impact on your health and can trigger the onset of all sorts of diseases including Hashimotos and other autoimmune diseases. […] Another common trigger of Hashimotos (and other autoimmune diseases) are INFECTIONS. […] Treating the EBV virus, in this case, can potentially have a positive impact on Hashimotos.

• #36 Hashimoto’s disease: MedlinePlus GeneticsLock

  https://medlineplus.gov/genetics/condition/hashimotos-disease/

  Hashimoto’s disease is thought to result from a combination of genetic and environmental factors. Some of these factors have been identified, but many remain unknown. […] Hashimoto’s disease is classified as an autoimmune disorder, one of a large group of conditions that occur when the immune system attacks the body’s own tissues and organs. In people with Hashimoto’s disease, white blood cells called lymphocytes accumulate abnormally in the thyroid, which can damage it. The lymphocytes make immune system proteins called antibodies that attack and destroy thyroid cells. When too many thyroid cells become damaged or die, the thyroid can no longer make enough hormones to regulate body functions. This shortage of thyroid hormones underlies the signs and symptoms of Hashimoto’s disease. However, some people with thyroid antibodies never develop hypothyroidism or experience any related signs or symptoms.

• #37 Hashimoto’s Thyroiditis: Symptoms, Causes, and Treatment – Endocrinemds

  https://www.endocrinemds.com/blogs/hashimotos-thyroiditis-symptoms-causes-and-treatment/

  At the root of Hashimotos is an autoimmune response where the bodys immune system mistakenly attacks the thyroid gland. This leads to inflammation and gradual destruction of thyroid tissue over time. […] The most common cause of Hashimotos thyroiditis is an autoimmune response. In Hashimotos, the bodys immune system mistakenly attacks and damages the thyroid gland, leading to an underactive thyroid (hypothyroidism). The exact trigger for this autoimmune response is not fully understood, but it is believed to involve a combination of genetic and environmental factors. […] Individuals with a family history of Hashimotos or other autoimmune disorders have a higher risk of developing the condition. Environmental triggers like viral infections, exposure to radiation, hormonal changes, and certain medications may also contribute to the autoimmune response in genetically predisposed individuals.

• #38 Thyroid – Hashimoto’s disease | Better Health Channel

  https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/thyroid-hashimotos-disease

  Hashimotos disease is a common cause of hypothyroidism (underactive thyroid). […] Hashimotos disease is an autoimmune condition. Immune system cells attack the thyroid gland, causing inflammation and, in most cases, eventual destruction of the gland. This reduces the thyroids ability to make hormones. […] Hashimotos disease is considered to be an autoimmune disease. Immune system cells that normally defend the body against foreign invaders (such as disease-causing bacteria and viruses) attack the thyroid gland. […] The cause of the immune system attack against the thyroid gland is unknown. Most medical researchers believe that a number of both genetic and environmental factors working in combination cause Hashimotos disease. Current theories include: Some type of microbe, such as a bacterium or virus, may prompt the immune system to attack the thyroid. […] A genetic defect may trigger the immune response. Genetic factors may play an important role, since women are more commonly affected. […] Hashimotos disease also tends to run in families, which suggests that heredity may be important.

• #39 Hashimoto Thyroiditis | Cedars-Sinai

  https://www.cedars-sinai.org/health-library/diseases-and-conditions/h/hashimotos-thyroiditis.html

  Hashimoto thyroiditis is an autoimmune disorder. Normally, your immune system protects your body by attacking bacteria and viruses. But with this disease, your immune system attacks your thyroid gland by mistake. Your thyroid then cant make enough thyroid hormone, so your body cant work as well. […] Hashimoto thyroiditis is the most common type of this health problem. It may also be called chronic autoimmune thyroiditis. This thyroiditis is an autoimmune disease. It occurs when your body makes antibodies that attack the cells in your thyroid. […] It’s an autoimmune disease. It occurs when your body makes antibodies that attack the cells in your thyroid.

• #40 Hashimoto’s Thyroiditis

  https://www.thyroidcancer.com/hashimotos-thyroiditis

  Hashimotos thyroiditis is an autoimmune disease where the immune system malfunctions. We do not know exactly why it occurs, but we think it is multifactorial. Excessive iodine may trigger thyroid disease. There is likely a hormonal component because women are affected much more commonly than men. Lastly, there is likely a genetic component because Hashimotos thyroiditis runs in families who have thyroid disease or autoimmune diseases. Some anecdotal evidence suggests that dietary gluten may contribute to Hashimotos thyroiditis and dietary changes may improve some symptoms. […] Regardless of the cause, we know that the immune system is finding our thyroid gland abnormal and mounts an antibody attack against the gland. Instead of the immune system protecting the body, the immune system makes antibodies that attack the thyroid gland. A large number of lymphocytes or white blood cells, that are part of the immune system, build up in the thyroid and produce antibodies. These antibodies are anti-thyroid antibodies that are more specifically called thyroid peroxidase antibodies and the anti-thyroglobulin antibodies.

• #41 Hashimoto thyroiditis | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/hashimoto-thyroiditis?lang=us

  Hashimoto thyroiditis, also known as lymphocytic thyroiditis or chronic autoimmune thyroiditis, is a subtype of autoimmune thyroiditis. It is one of the most common thyroid disorders and causes of hypothyroidism. […] There is autoimmunity to the thyroid gland which bears both humoral- and cell-mediated features. This is followed by lymphocytic infiltration of the thyroid gland with lymphoid follicles replacing thyroid follicles. […] A small proportion of cases (~5%) can present with hyperthyroidism (also known as Hashitoxicosis), which usually only lasts 1-2 months. […] The diagnosis of Hashimoto’s thyroiditis is usually based on the combination of clinical features, serology results, and ultrasound findings. However, cytology/histology remains the gold standard for diagnosis. […] Patients are at higher risk for papillary thyroid carcinoma, so a discrete nodule should be considered for biopsy.

• #42 Thyroiditis: Evaluation and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2021/1200/p609.html

  Hashimoto thyroiditis is an autoimmune disorder that presents with or without signs or symptoms of hypothyroidism, often with a painless goiter, and is associated with elevated thyroid peroxidase antibodies. […] HT occurs due to the formation of autoantibodies and direct injury to the thyroid from an environmental trigger (e.g., infection, stress, iodine intake) in patients with genetic susceptibility. […] The degree of injury can differ among individuals but is often progressive over time and can result in fibrotic transformation of the gland. […] The diagnosis of HT can be established by a combination of clinical features, thyroid function test results consistent with subclinical hypothyroidism (elevated serum TSH level, but normal serum levels of T4 and free triiodothyronine [T3]) or overt hypothyroidism (elevated TSH level with low T4 and T3 serum levels), and elevated thyroglobulin and thyroid peroxidase (TPO) antibodies. […] TPO antibodies are found in 95% of patients with HT, whereas thyroglobulin antibodies are elevated in 60% to 80% of patients with HT. […] Hashimoto thyroiditis: clinical and diagnostic criteria. […] Hashimoto’s thyroiditis: history and future outlook. […] Chronic autoimmune thyroiditis.

• #43 Hashimoto’s thyroiditis | Hashimoto’s disease – Symptoms & Causes PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact

  https://www.pacehospital.com/hashimoto-s-thyroiditis-hashimotos-disease

  Exposure to environmental toxins, such as nuclear radiation. […] Hashimoto disease is characterised by the production of antibodies by the immune system that targets the thyroid gland. […] The white blood cells of the patient’s immune system accumulate in the thyroid, causing inflammation and damage to the thyroid cells and a reduction in the gland’s ability to produce the necessary hormones. […] This can lead to hypothyroidism, a condition in which the thyroid does not make enough hormones for the body’s needs.

• #44 Become a member

  https://www.btf-thyroid.org/thyroid-antibodies-explained

  The presence of antibodies is used to confirm the diagnosis of autoimmune thyroid diseases. Some people will test positive for more than one type of thyroid antibody. It is possible to test positive for thyroid antibodies without having thyroid disease. The presence of antibodies in a person with subclinical (or borderline) thyroid disease can indicate a person may go on to develop full-blown thyroid disease in the future.

• #45 Root Cause Approach & Hashimoto’s – Dr. Izabella Wentz

  https://thyroidpharmacist.com/articles/root-cause-approach-and-hashimotos/

  The conventional approach limits its focus to the particular follow up appointment and labs, monitoring the medications effects at each visit, instead of having a practitioner truly partnering with the patient to figure out why their bucket is leaking in the first place (and what they can do about it). […] The Root Cause approach also focuses on reversing the autoimmune attack on the thyroid. […] Autoimmune issues can be reversed. […] All three requirements of this three-legged stool must be present, or a person will not develop an autoimmune disease. […] Based on this, by removing one of the factors of autoimmunity, we can reverse Hashimotos. […] In autoimmune disease, a person’s body recognizes normally occurring physiological processes as foreign invaders, and attacks itself. […] The problem is not with our thyroid function, but rather, the function of our immune system.

• #46 Hashimoto’s Disease Symptoms And Causes | The Fork Clinic

  https://www.theforkclinic.com/post/hashimotos-disease-symptoms-and-causes

  Hashimotos disease, or Hashimotos thyroiditis, is one of the most common autoimmune disorders. […] What causes Hashimotos disease? […] Hashimotos is characterized by thyroid-specific antibodies that causes damage to the thyroid gland and ultimately hypothyroidism, or underactive thyroid. […] Those with Hashimotos thyroiditis have a higher risk of developing other autoimmune disease, such as Celiac disease and rheumatoid arthritis. […] To understand Hashimotos, we must understand the root causes of autoimmunity. Autoimmune disease results from an interaction between genetics and environmental factors. In autoimmune disease, there are three factors that must be present for disease to develop. […] In the case of Hashimotos thyroid disease, common triggers and underlying contributors include:

• #47 Root Cause Approach & Hashimoto’s – Dr. Izabella Wentz

  https://thyroidpharmacist.com/articles/root-cause-approach-and-hashimotos/

  When I was diagnosed with Hashimotos in 2009, I was told I had low levels of thyroid hormones (because my TSH was elevated), and that I needed to take thyroid hormone meds to replenish my thyroid hormones. […] If you have Hashimotos, there is an autoimmune component causing your thyroid to be actively destroyed by the immune system. […] Everyones root causes of Hashimotos will be different, as we all have our own unique genetics, medical histories, and lifestyles. […] The issue with this for someone having Hashimotos is that TSH often tests as abnormal only after a lot of damage to the thyroid has already been done. […] There are 5 stages of disease progression in developing Hashimotos, and TSH doesn’t usually test as abnormal until stage 4! […] Thyroid antibodies are typically seen much sooner than an abnormal TSH level, usually as early as stage 2, but this testing doesn’t fall under the standard of care that a physician would routinely order for thyroid symptoms.

• #48 What Causes Hashimoto’s – Team Health Care Clinic

  https://teamhealthcareclinic.com/blog/what-causes-hashimotos/

  Hashimotos is an autoimmune disease. Your body doesnt recognize your thyroid as your own and attacks it. […] The exact cause of Hashimotos is not known, but many factors are proven to heighten the risk of developing the disease. […] Instead of protecting your thyroid tissue, your immune cells attack it. Causing hypothyroidism and over time if left untreated, can cause autoimmune disorders and completely destroy your thyroid. […] In someone with Hashimotos thyroiditis, a bunch of damaged immune cells attack the thyroid. […] When patients are diagnosed with Hashimotos, it has usually been progressing slowly over a long period of time. Causing chronic thyroid damage. […] Hashimotos thyroiditis should be diagnosed by blood tests that measure thyroid gland function and blood tests that look for antibodies against proteins found in the thyroid gland. […] In most patients, hypothyroidism results from the inflammatory process.

• #49 Why Did I Get Hashimoto’s Hypothyroidism? 9 Causes | RedRiver

  https://www.redriverhealthandwellness.com/why-did-i-get-hashimotos-nine-things-that-can-trigger-autoimmune-hashimotos-hypothyroidism/

  If you do not take action to manage the autoimmune disease and dampen the inflammation its causing, your risk for developing more autoimmune diseases is substantially higher. […] For instance, in our practice, we find 50 percent of our Hashimotos patients also have autoimmune reactions against the brain and nerve tissue, it just hasnt been diagnosed yet. […] Although science yet has much to learn about autoimmunity, researchers have discovered quite a bit about what may lead to autoimmune diseases such as Hashimotos hypothyroidism. […] Perhaps the most important thing to know is that in most cases, it doesnt appear that just one thing can trigger autoimmunity. Usually predisposing health imbalances and an increasingly burdened immune system make it more vulnerable to autoimmunity. […] Leaky gut significantly raises your risk of developing an autoimmune disease due to the chronic inflammation and immune imbalance it causes.

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