Materiały źródłowe

• #1 Acute myeloid leukemia – Wikipedia

  https://en.wikipedia.org/wiki/Acute_myeloid_leukemia

  Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection. […] As an acute leukemia, AML progresses rapidly, and is typically fatal within weeks or months if left untreated. […] Most signs and symptoms of AML are caused by the crowding out in bone marrow of space for normal blood cells to develop. A lack of normal white blood cell production makes people more susceptible to infections. A low red blood cell count (anemia) can cause fatigue, paleness, shortness of breath and palpitations. A lack of platelets can lead to easy bruising, bleeding from the nose (epistaxis), small blood vessels on the skin (petechiae) or gums, or bleeding with minor trauma. Other symptoms may include fever, fatigue worse than what can be attributed to anemia alone, weight loss and loss of appetite.

• #2 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://my.clevelandclinic.org/health/diseases/6212-acute-myeloid-leukemia-aml

  Acute myeloid leukemia (AML) is a rare cancer that affects your bone marrow and blood. Its an aggressive cancer that, left untreated, may be life-threatening. AML typically affects people age 60 and older, but it can affect younger adults and children. […] Early on, AML symptoms may feel like you have a cold or flu that wont go away. Acute myeloid leukemia is aggressive. That means you quickly develop new and more noticeable symptoms. Later symptoms include: Dizziness. Easy bruising or bleeding, including frequent nosebleeds and bleeding gums. Fatigue. Feeling cold. Fever. Night sweats. Frequent infections or infections that dont go away. Headaches. Loss of appetite. Unexplained weight loss. Pale skin. Shortness of breath (dyspnea). Swollen lymph nodes. Weakness. Bone, back or abdominal pain. Tiny red spots on your skin (petechiae). Wounds or sores that dont go away.

• #3 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin, Shortness of breath. […] Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another.

• #4

  https://www.nhs.uk/conditions/acute-myeloid-leukaemia/symptoms/

  The symptoms of acute myeloid leukaemia (AML) usually develop over a few weeks, becoming more severe as the number of immature white blood cells increases. […] Symptoms of AML can include: skin looking pale or „washed out”, tiredness, breathlessness, losing weight without trying, frequent infections, having a high temperature, and feeling hot or shivery (fever), night sweats, unusual and frequent bleeding, such as bleeding gums or nosebleeds, easily bruised skin, flat red or purple spots on the skin, bone and joint pain, a feeling of fullness or discomfort in your tummy, swollen glands in your neck, armpit or groin that may be sore when you touch them. […] See a GP if you or your child have the symptoms of AML. […] Although it’s highly unlikely that AML is the cause, these symptoms need to be investigated and treated promptly.

• #5 12 Top Acute Myeloid Leukemia Symptoms & Signs | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/acute-myeloid-leukemia/acute-myeloid-leukemia-symptoms.html

  Weakness, tiredness and fatigue. This can be caused by the leukemia itself or by the low levels of hemoglobin seen in many leukemia patients. […] Fever and frequent infections due to low counts of health white blood cells. […] Excessive sweating or night sweats […] Easy bleeding and bruising, including bleeding of the gums due to low platelet levels. […] Recurrent nose bleeds […] Petechiae, a rash-like collection of pinpoint spots on the skin caused by bleeding into the skin. This is also due to low levels of platelets. […] Shortness of breath. This can be caused by low hemoglobin levels and lung infections. […] Swollen lymph nodes in the neck, underarm, stomach or groin […] Loss of appetite or a full feeling after eating very little food due to enlargement of the spleen […] Unexplained weight loss […] Bone and joint pain […] For female patients, longer than normal or heavier than normal menstruation.

• #6 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin, Shortness of breath. […] Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another.

• #7 Acute Myeloid Leukemia (AML) – Blood Disorders – Merck Manual Consumer Version

  https://www.merckmanuals.com/home/blood-disorders/leukemias/acute-myeloid-leukemia-aml

  Acute myeloid leukemia is a life-threatening disease in which the cells that normally develop into the types of white blood cells called neutrophils, basophils, eosinophils, and monocytes become cancerous and rapidly replace normal cells in the bone marrow. […] People may be tired or pale, may be easily susceptible to infection and fever, and may bruise or bleed easily. […] The first symptoms of AML are very similar to those of acute lymphoblastic leukemia and result from the inability of the bone marrow to produce enough normal blood cells. […] Fever and excessive sweating may indicate infection, which may result from too few normal white blood cells. […] Weakness, fatigue, and paleness, which may result from too few red blood cells (anemia). Some people may have trouble breathing, a rapid heart rate, or chest pain.

• #8 AML (Acute) vs. CML (Chronic) Leukemia: What to Know

  https://www.verywellhealth.com/aml-vs-cml-5198393

  Acute myeloid leukemia (AML) and chronic myeloid leukemia (CML) have key differences. […] In AML, the disease comes on quickly, and without treatment, the affected person tends to decline rapidly. […] With CML, the condition comes on slowly and worsens over time. […] However, there can also be differences as well. With acute myeloid leukemia, patients may also experience symptoms such as: […] Feeling short of breath […] Bruising easily […] Loss of appetite with potential weight loss […] Petechiae (pinpoint spots underneath the skin caused by bleeding) […] Bone pain […] Frequent infections […] Painless lumps on the body. […] Besides distinct causes and differing symptoms, the speed of disease progression is different in AML than in CML. AML symptoms come on quickly over days to weeks. […] CML takes about three to four years to transition from the chronic to blast phase. […] AML is vigorously treated upon detection with chemotherapy and stem cell transplantation.

• #9 What Is Acute Myeloid Leukemia (AML)? Symptoms, Causes, Diagnosis, Treatment, and Prevention

  https://www.everydayhealth.com/leukemia/acute-myeloid-leukemia-aml-cancer-refractory-relapsed-prognosis-symptoms-treatment-more/

  With AML, cancer cells generally move quickly from the bone marrow into the blood. As the cells spread throughout the body, they can cause bone or joint pain, abdominal swelling, lumps or spots on the skin, and other changes. […] AML can sometimes spread to other organs. When it affects the brain and spinal cord, it can cause symptoms like headaches and weakness. […] People with AML may have general (nonspecific) symptoms that overlap with those of other, much more common health conditions. These include: Weight loss, Fatigue, Fever, Night sweats, Appetite loss. […] Because AML cells crowd out healthy blood-making cells in the bone marrow, people with AML may not have enough red blood cells, white blood cells, or platelets. This can cause the following symptoms typical of a blood disorder: Fatigue, Weakness, Feeling cold, Feeling dizzy or light-headed, Headaches, Pale skin, Shortness of breath, Infections, often with a fever, Bruises on the skin, Excess bleeding, nosebleeds, bleeding gums, or heavy menstrual bleeding. […] AML is a complex condition that can cause any of these symptoms.

• #10 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  A shortage of blood platelets is called thrombocytopenia. This can lead to: Bruises (or small red or purple spots) on the skin, Excess bleeding, Frequent or severe nosebleeds, Bleeding gums, Heavy periods (menstrual bleeding) in women. […] The cancer cells in AML (called blasts) are bigger than normal blood cells and have more trouble traveling through tiny blood vessels. If the blast count gets very high, these cells can clog up blood vessels and make it hard for normal red blood cells (and oxygen) to get to tissues. This is called leukostasis. […] Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas. […] Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly.

• #11 Childhood Acute Myeloid Leukemia (AML) | Dana-Farber Cancer Institute

  https://www.dana-farber.org/cancer-care/types/childhood-acute-myeloid-leukemia

  Bleeding and/or bruising: When the marrow is too crowded to allow platelets to be produced, your child may bruise more easily. You might notice petechiae (or tiny red dots) on the skin when a child has a low number of platelets. These are very small blood vessels that have „leaked” or bled. A blood count will show thrombocytopenia, a decreased number of platelets. […] Recurrent infections: Although there may be an unusually high number of white blood cells on your child’s blood count, these white blood cells are immature and do not fight infection. Your child may have had several viral or bacterial infections over the past few weeks and may show symptoms of an infection such as fever, runny nose, and cough. […] Bone and joint pain: Your child may also experience pain in bones and joints. This pain is usually a result of the bone marrow being overcrowded and „full.” […] Abdominal pain: Stomach aches may also be a symptom of leukemia. Leukemia cells can collect in your child’s kidney, liver, and spleen, causing enlargement of these organs. Pain in the abdomen may cause your child to lose his appetite and lose weight.

• #12 Acute Myeloid Leukemia (AML) – Hematology and Oncology – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/hematology-and-oncology/leukemias/acute-myeloid-leukemia-aml

  Symptoms include fatigue, pallor, easy bruising and bleeding, fever, and infection; symptoms of extramedullary leukemic infiltration are present in only about 5% of patients (often as skin manifestations). […] Symptoms of acute myeloid leukemia may be present for only days to weeks before diagnosis. The most common presenting symptoms are due to disrupted hematopoiesis with ensuing anemia, thrombocytopenia, and granulocytopenia. […] Anemia can manifest with fatigue, weakness, pallor, malaise, dyspnea on exertion, tachycardia, and exertional chest pain. […] Thrombocytopenia can cause mucosal bleeding, easy bruising, petechiae/purpura, epistaxis, bleeding gums, and heavy menstrual bleeding. […] Granulocytopenia (neutropenia) can lead to a high risk of infections, including those of bacterial, fungal, and viral etiologies. Patients may present with fevers and a severe and/or recurrent infection. The cause of fever often is not found, although granulocytopenia may lead to a rapidly progressing and potentially life-threatening bacterial infection.

• #13 Acute Myeloid Leukemia (AML) Clinical Presentation: History, Physical Examination

  https://emedicine.medscape.com/article/197802-clinical

  Patients with AML often have decreased neutrophil levels despite an increased total white blood cell (WBC) count. Patients generally present with fever, which may occur with or without specific documentation of an infection. Patients with the lowest absolute neutrophil counts (ANCs) (ie, 500 cells/L, especially 100 cells/L) have the highest risk of infection. […] Patients may present with bleeding gums and multiple ecchymoses. Bleeding may be caused by thrombocytopenia, coagulopathy that results from disseminated intravascular coagulation (DIC), or both. Potentially life-threatening sites of bleeding include the lungs, gastrointestinal (GI) tract, and central nervous system. […] Alternatively, disease manifestations may be the result of organ infiltration with leukemic cells. The most common sites of infiltration include the spleen, liver, gums, and skin. Infiltration occurs most commonly in patients with the monocytic subtypes of AML. Patients with splenomegaly note fullness in the left upper quadrant and early satiety.

• #14 Acute Myeloid Leukemia | Conditions | UCSF Health

  https://www.ucsfhealth.org/conditions/acute-myeloid-leukemia

  A low white blood cell count puts you at an increased risk of infection. The infection types vary, but signs of a possible infection include: Fever, Runny nose, Cough, Chest pain, Shortness of breath, Pain when urinating, Occasional diarrhea. […] If your white blood cell count gets too low, your ability to fight off infection may be seriously compromised. This makes you vulnerable to developing potentially life-threatening conditions, such as pneumonia (a lung infection) or sepsis (a severe response to infection).

• #15

  https://www.nhs.uk/conditions/acute-myeloid-leukaemia/complications/

  If you have acute myeloid leukaemia (AML), you may experience complications. These can be caused by the condition itself, although they can also occur as a side effect of treatment. […] Symptoms of an infection can include: a sore throat, a high temperature, and feeling hot or shivery (fever), flu-like symptoms, such as headaches, aching muscles and tiredness, breathlessness or a cough, pain when peeing. […] If you have AML, you might bleed and bruise more easily because of the low levels of platelets (clot-forming cells) in your blood. Bleeding may also be excessive. […] Serious bleeding can occur: inside the skull (intracranial haemorrhage) causing symptoms such as a severe headache, stiff neck, vomiting and confusion, inside the lungs (pulmonary haemorrhage) causing symptoms such as coughing up blood, breathing difficulties and a bluish skin tone (cyanosis), inside the stomach (gastrointestinal haemorrhage) causing symptoms such as vomiting blood and passing poos that are very dark or tar-like in colour. […] Most treatments used to treat AML can cause infertility. This is often temporary, but in some cases can be permanent.

• #16 Acute Myeloid Leukemia: Symptoms and Signs | MyLeukemiaTeam

  https://www.myleukemiateam.com/resources/acute-myeloid-leukemia-symptoms-and-signs

  Anemia can cause the following symptoms: Fatigue, Weakness or dizziness, Headaches, Uneven heart rhythms, Pale or yellowish skin, Chest pain or shortness of breath. […] Low levels of neutrophils can lead to infection. Signs of infection can include: Fever of at least 100.5 degrees Fahrenheit (38 degrees Celsius), Chills or sweating, Belly pain, Painful urination, Mouth sores or a sore throat, Coughing, Redness and swelling in a particular area. […] When you dont have enough platelets, you can have bleeding problems such as: Bleeding for a long time from small cuts, Bruising, Bleeding gums, Nosebleeds, Petechiae (small red spots that appear on your skin). […] This blockage can cause stroke-like symptoms, including weakness in one side of the body, confusion, headache, and slurred speech. […] This buildup can lead to additional signs and symptoms, including: Bone and joint pain, Belly pain or swelling, Skin rashes, Bleeding gums, Abdominal discomfort or pain, Seizures, Balance problems, Vision problems, Swollen lymph nodes, which appear as lumps in the neck, armpit, or groin.

• #17 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  A shortage of blood platelets is called thrombocytopenia. This can lead to: Bruises (or small red or purple spots) on the skin, Excess bleeding, Frequent or severe nosebleeds, Bleeding gums, Heavy periods (menstrual bleeding) in women. […] The cancer cells in AML (called blasts) are bigger than normal blood cells and have more trouble traveling through tiny blood vessels. If the blast count gets very high, these cells can clog up blood vessels and make it hard for normal red blood cells (and oxygen) to get to tissues. This is called leukostasis. […] Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas. […] Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly.

• #18 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #19 Acute Myelogenous Leukemia (AML) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/acute-myelogenous-leukemia-aml

  The most common signs and symptoms of acute myelogenous leukemia in children are: […] Anemia occurs when normal red blood cells can’t be produced because the bone marrow is overcrowded by leukemia cells. The anemic child may be more tired, take more naps, look pale, and her heart may be racing. The number of red blood cells on a blood count (expressed as „hemoglobin” or „hematocrit”) will be below normal. […] When the bone marrow cannot produce enough platelets, bleeding can occur, especially when the platelet numbers are less than 10-20,000/mm3. Low platelets can cause a child to bruise or bleed more easily. […] Pain in bones and joints is usually a result of the bone marrow being crowded with leukemic blasts. This is often mistaken for „growing pains.” […] The child with leukemia often shows non-specific symptoms of infection such as fever and fatigue. Although the blood count of a child with leukemia may show a high number of white blood cells, these cells are immature and do not normally fight infection. As a result, the child may have difficulty recovering from an ordinary childhood infection or may develop unusual infections.

• #20 Acute Myelogenous Leukemia (AML) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/acute-myelogenous-leukemia-aml

  Leukemia cells can collect in the kidneys, liver, and spleen, causing enlargement of these organs which can cause pain in the abdomen. This pain may lead to loss of appetite and weight loss. […] Lymph nodes filter the blood. Leukemia cells often collect in the nodes, causing swelling. Swelling occurs in lymph nodes in the neck, under the arms, in the groin, and chest. Sometimes it is difficult to distinguish the lymph nodes of leukemia from those that are a normal part of the body’s response to infection or allergy. […] In leukemia, cells can clump together in the thymus a gland under the breastbone and around the throat. This mass of cells can cause difficulty breathing. Any wheezing, coughing, and/or labored or painful breathing requires immediate medical attention.

• #21 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #22 Acute Myeloid Leukemia (AML) – Blood Disorders – Merck Manual Consumer Version

  https://www.merckmanuals.com/home/blood-disorders/leukemias/acute-myeloid-leukemia-aml

  Easy bruising and bleeding, sometimes in the form of nosebleeds or bleeding gums, which may result from too few platelets (thrombocytopenia). In some cases, people may bleed into their brain or abdomen. […] Leukemia cells can invade other organs. Leukemia cells in the bone marrow may cause bone and joint pain. A sense of fullness in the abdomen and sometimes pain can result when leukemia cells cause enlargement of the liver and spleen. […] AML cells can spread to the layers of tissue covering the brain and spinal cord (meninges), leading to leukemic meningitis, which may cause headaches, vomiting, stroke, and disturbances of vision, hearing, and facial muscles. […] In the subtype of AML called acute promyelocytic leukemia, bleeding or blood clotting problems often occur.

• #23 Leukemia Symptoms & Diagnosis | Herbert Irving Comprehensive Cancer Center (HICCC) – New York

  https://www.cancer.columbia.edu/cancer-types-care/types/leukemia/about-leukemia

  Acute leukemias can affect your brain and spinal cord, so you might have headaches, blurred vision, double vision, vomiting, or confusion. […] Immature white blood cells, called blasts, grow too quickly. You can have severe symptoms right away. […] People are often diagnosed with leukemia when their doctor finds abnormal blood counts during a routine physical exam. The symptoms depend on the type of blood cell thats being affected. […] Common Symptoms include fevers and night sweats, infections, shortness of breath, easy bruising, bleeding, ongoing exhaustion or fatigue, general weakness, weight loss, joint pain, swollen or tender lymph nodes, increased size of the liver or spleen, and swollen or bleeding gums.

• #24 Acute Myeloid Leukemia: What Your Patients Need to Know – Hematology Advisor

  https://www.hematologyadvisor.com/news/acute-myeloid-leukemia-what-your-patients-need-to-know/

  Acute myeloid leukemia (AML) progresses more rapidly than other forms of leukemia. […] Acute myeloid leukemia (AML), also known as acute myelogenous leukemia, is named for how acutely and rapidly the disease can progress. […] Symptoms of AML may vary in severity. They can seem nondescript, or stem from conditions brought on by AML, like anemia. These symptoms may include: Fatigue, Loss of appetite, Weight loss, Night sweats. […] Patients with AML-induced anemia may experience symptoms such as: Pale skin, Shortness of breath, Dizziness, Headaches, Frequent bleeding of the nose and gums, Easy and/or unexplained bruising. […] In addition, patients with AML may experience bone or joint pain if leukemia cells have built up in those areas.

• #25 Acute Myeloid Leukemia (AML) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/acute-myeloid-leukemia-aml

  Symptoms include fatigue, weakness, weight loss, loss of appetite, fever, shortness of breath […] In people with AML, symptoms usually develop and progress rapidly over the course of a few weeks. […] Because red blood cells carry oxygen to tissues and organs around the body, people with low levels of red blood cells may have shortness of breath and feel tired. […] Symptoms may include: Feeling tired/weakness, Fever, Shortness of breath, Easy bruising and/or bleeding, Frequent nosebleeds and/or bleeding gums, Heavy menstrual flow in women, Unintentional weight loss, Pale skin, Nosebleeds and/or bleeding gums, Frequent infections, Headache, Bone and joint pain, Tiny red spots on skin (caused by bleeding under the skin), Small bumps, nodules, and/or rash on skin, Vision problems, Abdominal swelling.

• #26 Acute Myeloid Leukemia – Leukemia Research Foundation

  https://leukemiarf.org/leukemia/acute-myeloid-leukemia/

  Acute myeloid leukemia (AML) is a blood cancer that starts in the blood and bone marrow and can progress rapidly. […] Without immediate treatment, AML becomes much harder to manage successfully. […] With AML, you can experience infections or easy bleeding. You may also experience anemia (fewer red blood cells), which can lead to reduced oxygen in the body. […] Left untreated, AML can be life threatening. […] Early acute myeloid leukemia symptoms can include fatigue or fever, making it hard to tell it apart from other illnesses. Symptoms may also include: bruising, excessive bleeding, including nosebleeds or bleeding gums, frequent infections, weakness, weight loss. […] Acute myeloid leukemia can often be difficult to manage because its so aggressive.

• #27 Acute Myeloid Leukemia (AML): Symptoms, Causes, Prognosis, and More

  https://www.healthline.com/health/acute-myeloid-leukemia

  In its early stages, the symptoms of AML may resemble the flu and you may have a fever and fatigue. […] Other symptoms can include: bone pain, frequent nosebleeds, bleeding and swollen gums, easy bruising, excessive sweating (particularly at night), shortness of breath, unexplained weight loss, heavier than normal periods in females. […] When it comes to most types of AML, around two-thirds of people are able to achieve remission, according to the American Cancer Society (ACS). […] The five-year survival rate for Americans with AML is 27.4 percent. The five-year survival rate for children with AML is between 60 and 70 percent. […] With early-phase detection and prompt treatment, remission is highly likely in most people. Once all signs and symptoms of AML have disappeared, you’re considered to be in remission. If you’re in remission for more than five years, you’re considered cured of AML.

• #28 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] In acute leukemia, the abnormal blood cells are immature blood cells (blasts). They can’t carry out their normal functions, and they multiply rapidly, so the disease worsens quickly. Acute leukemia requires aggressive, timely treatment.

• #29 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  Acute myeloid leukemia (AML) begins in the bone marrow and initially may cause flu-like symptoms. As abnormal white blood cells (cancerous cells) build up, these symptoms can change or worsen. As AML is an aggressive form of cancer, it can progress rapidly. […] As AML progresses towards the final stages, symptoms may become more severe. Body functions may slow down, and complications may arise. Cancerous cells multiply, which may prevent the bone marrow from making new blood cells. This can cause: Anemia, Bleeding, An increased risk of infection. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #30 Acute Myeloid Leukemia (AML) | Symptoms, Diagnosis & Treatment

  https://www.cincinnatichildrens.org/health/a/acute-myeloid-leukemia

  Acute myeloid leukemia (AML) is the second most common blood cancer in children. AML affects certain cells in the bone marrow (myeloid cells). These cells usually develop into normal, mature blood cells. In AML, these immature cells do not develop properly and become cancerous. The cells multiply rapidly, building up in the bone marrow and crowding out normal, healthy cells. They can spill into the bloodstream and travel throughout the body, disrupting the normal function of organs. […] The early symptoms of AML occur as cancerous blood cells fill up the bone marrow and crowd out normal blood cells. This can result in high white blood cell counts and low red blood cell and platelet counts. Symptoms include: Fever / infections, Fatigue and weakness, Pale appearance, Aches and pains in the bones, Easy bruising or bleeding, such as nosebleeds or heavy menstrual periods, A swollen belly (from an enlarged liver and spleen), Tumors in the skin or gums. […] These signs and symptoms usually occur over days to a few weeks and worsen over time.

• #31 Leukemia: Symptoms, Signs, Causes, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/4365-leukemia

  Symptoms depend, in part, on the type of leukemia. For instance, if you have a chronic form of leukemia, you may not have noticeable symptoms in the early stages. […] Common signs and symptoms of leukemia include: Fatigue, tiring easily. Fever or night sweats. Frequent infections. Shortness of breath. Pale skin. Unexplained weight loss. Bone/joint pain or tenderness. Pain or full feeling under your ribs on the left side. Swollen lymph nodes in your neck, underarm, groin or stomach, an enlarged spleen or liver. Bruising and bleeding easily, including nosebleeds, bleeding gums, a rash that looks like tiny red spots in skin (petechiae) or purplish/darkened skin patches. […] If you have acute leukemia, you’ll feel sick within weeks of the leukemia cells forming. Acute leukemia is life-threatening and requires immediate initiation of therapy.

• #32 Acute Myelogenous Leukemia (AML) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/acute-myelogenous-leukemia-aml

  Leukemia cells can collect in the kidneys, liver, and spleen, causing enlargement of these organs which can cause pain in the abdomen. This pain may lead to loss of appetite and weight loss. […] Lymph nodes filter the blood. Leukemia cells often collect in the nodes, causing swelling. Swelling occurs in lymph nodes in the neck, under the arms, in the groin, and chest. Sometimes it is difficult to distinguish the lymph nodes of leukemia from those that are a normal part of the body’s response to infection or allergy. […] In leukemia, cells can clump together in the thymus a gland under the breastbone and around the throat. This mass of cells can cause difficulty breathing. Any wheezing, coughing, and/or labored or painful breathing requires immediate medical attention.

• #33 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  A shortage of blood platelets is called thrombocytopenia. This can lead to: Bruises (or small red or purple spots) on the skin, Excess bleeding, Frequent or severe nosebleeds, Bleeding gums, Heavy periods (menstrual bleeding) in women. […] The cancer cells in AML (called blasts) are bigger than normal blood cells and have more trouble traveling through tiny blood vessels. If the blast count gets very high, these cells can clog up blood vessels and make it hard for normal red blood cells (and oxygen) to get to tissues. This is called leukostasis. […] Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas. […] Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly.

• #34 Acute Myeloid Leukemia (AML) Clinical Presentation: History, Physical Examination

  https://emedicine.medscape.com/article/197802-clinical

  Patients with markedly elevated WBC counts (100,000 cells/L) can present with symptoms of leukostasis (ie, respiratory distress and altered mental status). Leukostasis is a medical emergency that calls for immediate intervention. Patients with a high leukemic cell burden may present with bone pain caused by increased pressure in the bone marrow.

• #35 Acute Myeloid Leukemia – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507875/

  Common physical examination findings in AML include pallor, bruising, and hepatosplenomegaly, while lymphadenopathy is rare. Myeloid sarcoma, a myeloid equivalent, may present as thickened, hyperpigmented, coarse skin lesions. Disseminated intravascular coagulation (DIC), characterized clinically by oral mucosal hemorrhages, purpura, extremity petechiae, and bleeding from intravenous line sites, is common in AML. […] AML should be suspected in individuals presenting with rapid (within days or a few weeks) unexplained cytopenias (decreased leukocytes, hemoglobin, or platelets), circulating blast cells in peripheral blood, easy bruising or bleeding, or recurrent infections. In some cases, patients may present with renal failure due to auto-tumor lysis syndrome (auto-TLS), which, even in the absence of prior chemotherapy, is considered an oncologic emergency. […] Characteristic laboratory findings indicative of auto-tumor lysis, stemming from high tumor burden and rapid cell turnover, often include elevated LDH, uric acid, potassium, and phosphorus levels.

• #36 Acute Myeloid Leukemia – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507875/

  Common physical examination findings in AML include pallor, bruising, and hepatosplenomegaly, while lymphadenopathy is rare. Myeloid sarcoma, a myeloid equivalent, may present as thickened, hyperpigmented, coarse skin lesions. Disseminated intravascular coagulation (DIC), characterized clinically by oral mucosal hemorrhages, purpura, extremity petechiae, and bleeding from intravenous line sites, is common in AML. […] AML should be suspected in individuals presenting with rapid (within days or a few weeks) unexplained cytopenias (decreased leukocytes, hemoglobin, or platelets), circulating blast cells in peripheral blood, easy bruising or bleeding, or recurrent infections. In some cases, patients may present with renal failure due to auto-tumor lysis syndrome (auto-TLS), which, even in the absence of prior chemotherapy, is considered an oncologic emergency. […] Characteristic laboratory findings indicative of auto-tumor lysis, stemming from high tumor burden and rapid cell turnover, often include elevated LDH, uric acid, potassium, and phosphorus levels.

• #37 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  Acute myeloid leukemia (AML) begins in the bone marrow and initially may cause flu-like symptoms. As abnormal white blood cells (cancerous cells) build up, these symptoms can change or worsen. As AML is an aggressive form of cancer, it can progress rapidly. […] As AML progresses towards the final stages, symptoms may become more severe. Body functions may slow down, and complications may arise. Cancerous cells multiply, which may prevent the bone marrow from making new blood cells. This can cause: Anemia, Bleeding, An increased risk of infection. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #38 End stage AML: Symptoms, care, comfort, and more

  https://www.medicalnewstoday.com/articles/signs-of-dying-from-aml

  Every person will experience end stage AML differently. The symptoms can vary based on their overall health, age, the extent of the disease, and whether they have any other conditions. […] Doctors often observe the following signs and symptoms in people with end stage AML: […] Symptoms relating to energy and motivation may include: profound weakness and exhaustion, resting or sleeping most of the time, loss of interest in events and things previously held as important. […] Symptoms that affect a persons muscles include: thinning or loss of muscles, reduced ability to talk, needing assistance in almost everything. […] Food intake and metabolism symptoms may include: weight loss, little to no appetite, altered sense of taste, feeling full quickly, difficulty eating, drinking, or taking medication.

• #39 End stage AML: Symptoms, care, comfort, and more

  https://www.medicalnewstoday.com/articles/signs-of-dying-from-aml

  Every person will experience end stage AML differently. The symptoms can vary based on their overall health, age, the extent of the disease, and whether they have any other conditions. […] Doctors often observe the following signs and symptoms in people with end stage AML: […] Symptoms relating to energy and motivation may include: profound weakness and exhaustion, resting or sleeping most of the time, loss of interest in events and things previously held as important. […] Symptoms that affect a persons muscles include: thinning or loss of muscles, reduced ability to talk, needing assistance in almost everything. […] Food intake and metabolism symptoms may include: weight loss, little to no appetite, altered sense of taste, feeling full quickly, difficulty eating, drinking, or taking medication.

• #40 End stage AML: Symptoms, care, comfort, and more

  https://www.medicalnewstoday.com/articles/signs-of-dying-from-aml

  Consciousness-related symptoms may include: an inability to focus, poor and short attention, difficulty waking from sleep, hallucinations or delusions, less responsive to touch, sound, or other stimuli. […] Circulation signs and symptoms may include: blood pressure dropping, irregular pulse, a heartbeat that is difficult to hear. […] Breathing symptoms may include: neck muscles appearing tight due to difficulty breathing, changes in breathing rate, slow breathing with pauses or interruptions. […] As a person approaches the later stages of AML, they may experience pain, fatigue, appetite loss, difficulty focusing and speaking, muscle loss, weakness, low blood pressure, and breathing difficulty, among other symptoms. […] During end stage AML, the focus shifts from treatment to providing comfort and maintaining quality of life. Individuals at this stage present with several symptoms that indicate that death could be imminent.

• #41 Final Stages of Acute Myeloid Leukemia: Symptoms & Support

  https://www.healthline.com/health/final-stages-of-acute-myeloid-leukemia

  Acute myeloid leukemia (AML) is a progressive type of cancer that affects your bone marrow and blood cells. […] Early detection and treatment are important to help increase the chances of survival from this cancer. See a doctor right away if you notice any possible early symptoms. These include: recurring infections, chronic fever, unusual bleeding. […] Symptoms of the final stages of AML are similar to end-stage symptoms of all types of leukemia. These may include: cool, dry skin, slow or labored breathing, blurry vision, decreased urination or incontinence, restlessness or involuntary muscle movements, decreased movements or weakness, loss of appetite and decreased fluid intake, increased drowsiness and sleepiness, changes in heart rate, signs of bleeding, such as under the skin (petechiae) or from the nose, pain, hallucinations, confusion, loss of consciousness.

• #42 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  Acute myeloid leukemia (AML) begins in the bone marrow and initially may cause flu-like symptoms. As abnormal white blood cells (cancerous cells) build up, these symptoms can change or worsen. As AML is an aggressive form of cancer, it can progress rapidly. […] As AML progresses towards the final stages, symptoms may become more severe. Body functions may slow down, and complications may arise. Cancerous cells multiply, which may prevent the bone marrow from making new blood cells. This can cause: Anemia, Bleeding, An increased risk of infection. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #43 End stage AML: Symptoms, care, comfort, and more

  https://www.medicalnewstoday.com/articles/signs-of-dying-from-aml

  Every person will experience end stage AML differently. The symptoms can vary based on their overall health, age, the extent of the disease, and whether they have any other conditions. […] Doctors often observe the following signs and symptoms in people with end stage AML: […] Symptoms relating to energy and motivation may include: profound weakness and exhaustion, resting or sleeping most of the time, loss of interest in events and things previously held as important. […] Symptoms that affect a persons muscles include: thinning or loss of muscles, reduced ability to talk, needing assistance in almost everything. […] Food intake and metabolism symptoms may include: weight loss, little to no appetite, altered sense of taste, feeling full quickly, difficulty eating, drinking, or taking medication.

• #44 Acute Myeloid Leukemia (AML) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/acute-myeloid-leukemia-aml

  Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. It tends to affect older people […] This is an encouraging time for the treatment of AML, for which many targeted therapies are now standards of care and many more are in development with promising initial results, he adds.

• #45 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://my.clevelandclinic.org/health/diseases/6212-acute-myeloid-leukemia-aml

  If you dont have enough healthy blood cells and platelets, you may develop the following conditions: Anemia. Thrombocytopenia. Pancytopenia (low blood cell and platelet levels). […] Currently, allogeneic stem cell transplantation is the only way to cure acute myeloid leukemia. Depending on your situation, your provider may recommend stem cell transplantation as your first AML treatment or if you have AML that comes back within 12 months. […] Overall, an estimated 50% to 80% of people with acute myeloid leukemia achieve complete remission after treatment. Complete remission happens more often in children and people under age 60. Remission may last for months or years. About 50% of people who achieve complete remission develop recurrent AML. When that happens, providers may recommend additional chemotherapy or stem cell transplantation. They may suggest participation in a clinical trial.

• #46 AML vs. CML: How Do These Leukemia Types and Their Treatments Differ? | MyLeukemiaTeam

  https://www.myleukemiateam.com/resources/aml-vs-cml-how-are-these-leukemia-types-different

  AML is classified into subtypes based on the cancer cells characteristics, including their appearance under a microscope, genetic abnormalities, and blood cell counts. […] CML is classified by phases chronic, accelerated, and blast. Compared with people who have chronic phase CML, people with accelerated or blast-phase CML have more leukemia cells. If CML progresses to the blast phase, the symptoms can be very similar to those of AML. […] People with CML often have a better prognosis (outlook) than those with AML. According to Cleveland Clinic, about 90 percent of people with CML and about 32 percent of people with AML survive for five years or more after diagnosis.

• #47 Just diagnosed with AML – Recent diagnosis – Blood Cancer UK Online Community Forum

  https://forum.bloodcancer.org.uk/t/just-diagnosed-with-aml/9975

  After a rollercoaster of a few days from a gp appointment, blood tests, next day appointment in haematology, more blood tests and consultant telling me he was 99% sure I had acute leukemia, today I was diagnosed with Acute myeloid leukemia (Acute myeloid leukaemia (AML)). My only symptoms were unexplained bruising and fatigue, consultant reckons I have probably had Acute myeloid leukaemia (AML) for a few months. […] It sounds like everything will be happening quite quickly here on in for you, which is very typical of Acute myeloid leukaemia (AML). […] The worst bit was the wait for the genetics to come through – the bone marrow biopsy quickly confirmed acute myeloid leukaemia, but the genetics was needed to determine what happened next. […] Basically, even within Acute myeloid leukaemia (AML), there are so many different mutations that people can have. The mutations are really important because they will enable your care team to create a tailored treatment plan.

• #48 Reddit – The heart of the internet

  https://www.reddit.com/r/leukemia/comments/157jmy3/what_to_expect_aml/

  I guess I wanted to know what to expect going forward. Any idea how fast this might progress? What does the progression look like? […] The doctor said blasts are 47% and very low white cell count and platelets.

• #49 Final Stages of Acute Myeloid Leukemia: Symptoms & Support

  https://www.healthline.com/health/final-stages-of-acute-myeloid-leukemia

  While AML can progress rapidly, an early diagnosis followed by aggressive treatment may help you live as long as possible. […] Despite treatment, there are certain factors that can increase the risk of reaching the end stages of AML. These include older age, cancer subtype, and whether the cancer has spread to vital organs.

• #50 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://my.clevelandclinic.org/health/diseases/6212-acute-myeloid-leukemia-aml

  If you dont have enough healthy blood cells and platelets, you may develop the following conditions: Anemia. Thrombocytopenia. Pancytopenia (low blood cell and platelet levels). […] Currently, allogeneic stem cell transplantation is the only way to cure acute myeloid leukemia. Depending on your situation, your provider may recommend stem cell transplantation as your first AML treatment or if you have AML that comes back within 12 months. […] Overall, an estimated 50% to 80% of people with acute myeloid leukemia achieve complete remission after treatment. Complete remission happens more often in children and people under age 60. Remission may last for months or years. About 50% of people who achieve complete remission develop recurrent AML. When that happens, providers may recommend additional chemotherapy or stem cell transplantation. They may suggest participation in a clinical trial.

• #51 Acute Myeloid Leukemia (AML): Symptoms, Treatment & Prognosis

  https://my.clevelandclinic.org/health/diseases/6212-acute-myeloid-leukemia-aml

  If you dont have enough healthy blood cells and platelets, you may develop the following conditions: Anemia. Thrombocytopenia. Pancytopenia (low blood cell and platelet levels). […] Currently, allogeneic stem cell transplantation is the only way to cure acute myeloid leukemia. Depending on your situation, your provider may recommend stem cell transplantation as your first AML treatment or if you have AML that comes back within 12 months. […] Overall, an estimated 50% to 80% of people with acute myeloid leukemia achieve complete remission after treatment. Complete remission happens more often in children and people under age 60. Remission may last for months or years. About 50% of people who achieve complete remission develop recurrent AML. When that happens, providers may recommend additional chemotherapy or stem cell transplantation. They may suggest participation in a clinical trial.

• #52 Acute myeloid leukemia – Wikipedia

  https://en.wikipedia.org/wiki/Acute_myeloid_leukemia

  The clinical signs and symptoms of AML result from the growth of leukemic clone cells, which tends to interfere with the development of normal blood cells in the bone marrow. This leads to neutropenia, anemia, and thrombocytopenia. Other symptoms can arise from the infiltration of malignant cells into parts of the body, such as the gingiva and skin.

• #53

  https://www.nhs.uk/conditions/acute-myeloid-leukaemia/symptoms/

  The symptoms of acute myeloid leukaemia (AML) usually develop over a few weeks, becoming more severe as the number of immature white blood cells increases. […] Symptoms of AML can include: skin looking pale or „washed out”, tiredness, breathlessness, losing weight without trying, frequent infections, having a high temperature, and feeling hot or shivery (fever), night sweats, unusual and frequent bleeding, such as bleeding gums or nosebleeds, easily bruised skin, flat red or purple spots on the skin, bone and joint pain, a feeling of fullness or discomfort in your tummy, swollen glands in your neck, armpit or groin that may be sore when you touch them. […] See a GP if you or your child have the symptoms of AML. […] Although it’s highly unlikely that AML is the cause, these symptoms need to be investigated and treated promptly.

• #54 Acute Myeloid Leukemia: AML Symptoms, Treatment & Survival Rate

  https://www.cancercenter.com/cancer-types/leukemia/types/acute-myeloid-leukemia

  Acute myeloid leukemia (AML) is a fast-growing form of cancer of the blood and bone marrow. […] Because AML makes abnormal cells that crowd out normal healthy cells, many of its symptoms are a result of the low number of healthy blood cells in the body. Some AML symptoms include those listed below. […] The job of white blood cells is to ward off infections and protect our bodies from foreign germs and bacteria. Because AML reduces the number of healthy white blood cells, the body is not as capable of defending against foreign germs and bacteria. Therefore, patients with AML may have an increased rate of infections and fevers. […] The low level of healthy blood cells caused by AML may lead to feeling tired and/or weak, having shortness of breath and looking pale. […] Having low levels in the blood can lead to easy bleeding or bruising. This can result in the slow healing of cuts, prolonged bleeding from minor cuts and bruises with no clear cause. It can also lead to petechiae, tiny red spots under the skin.

• #55 Acute Myeloid Leukemia: AML Symptoms, Treatment & Survival Rate

  https://www.cancercenter.com/cancer-types/leukemia/types/acute-myeloid-leukemia

  The increased number of leukemia cells can cause pain in bones, joints or both. […] Patients with a low red blood cell count may feel lightheaded or dizzy. […] Low level of healthy blood cells may result in feeling tired and run down. […] One general symptom of AML may include waking up feeling sweaty during the night. […] Patients with a low red blood cell count may frequently feel cold. […] A nonspecific symptom of AML may include unexplained weight loss. […] Feeling short of breath may occur in patients with a low red blood cell count. […] If AML spreads to the lymph nodes, they may feel enlarged, especially around the groin, neck, underarm area and just above the collarbone. […] Some AML symptoms are general in nature and dont, on their own, mean someone has AML, since they may be caused by other health conditions. The patient should always speak to his or her doctor after noticing unexpected health or bodily changes.

• #56 Symptoms of acute myeloid leukaemia AML | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/acute-myeloid-leukaemia-aml/symptoms

  Less common symptoms include lumps on the skin and swollen lymph nodes. Your lymph nodes (glands) might feel swollen when you touch them. You have lymph nodes in lots of places in your body. They might feel swollen in: your neck […] under your armpit […] in your groin. If you have any of these symptoms, you must get checked out by your GP. The symptoms of AML are often vague and can be caused by other medical conditions. The earlier an acute leukaemia is picked up, the easier it is to treat and the more likely treatment is to be successful. So go to your GP as soon as possible.

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