Materiały źródłowe

• #1 Hyperhidrosis prevalence and its impact on population – Hasimoto – Shanghai Chest

  https://shc.amegroups.org/article/view/5114/html

  Hyperhidrosis is a disorder characterized by excessive sweating which beyond the physiological need for body thermoregulation. The prevalence data available in the literature are practically nonexistent up to the beginning of the 21st century. The prevalence found in the articles varied from 0.072% to 16.3%. As to the impact on the quality of life, all articles have shown that such disorder affects in some way the life of the individuals. The data available in the literature regarding the prevalence of hyperhidrosis in the world population are practically nonexistent until the beginning of the 21st century, therefore up to some time ago little was known about the number of individuals bearing this disorder. The bibliographic review was done by using the PubMed database (until January 10th 2019). Sixteen articles that evaluated the prevalence of hyperhidrosis were found in the research, 15 of them were published from the 21st century. The prevalence of hyperhidrosis found in the articles ranged from 0.072% to 16.3%. The first citation found in the literature about the prevalence of hyperhidrosis is from 1977. The first published work with methodological description was the one by Strutton et al. in 2004. In 2007 China published two studies about the prevalence of hyperhidrosis. The lowest prevalence of published hyperhidrosis was 0.072%, by Chu et al. The highest prevalence published among all published papers was the one by Augustin et al. in 2013. The most recent work about the prevalence of hyperhidrosis belongs to our group, published in 2018. The existing data of hyperhidrosis prevalence in the world population are well varied and questionable due to the heterogeneity of methodologies used in several studies. The impacts of hyperhidrosis in the quality of life of the individuals are well known in daily practice and are confirmed by means of the applied questionnaires aimed at measuring the severity and the interference of the disorder in the daily life of its patient.

• #1 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Hyperhidrosis-Prognosis-and-Epidemiology.aspx

  Hyperhidrosis refers to excessive sweating that does not necessarily occur in response to the body becoming overheated by exercise or a hot environment, for example. […] It is difficult to say how many people develop hyperhidrosis as there are no guidelines to determine exactly what constitutes normal sweating, but estimates suggest that the worldwide prevalence is between 2% and 4%, without any particular gender predisposition. […] There are differences in prevalence globally, with one study, for example, having shown a prevalence of 2.9% in the US and up to 5.0% prevalence in certain areas of China.

• #1 Hyperhidrosis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/1073359-overview

  In the United States and the United Kingdom, 1-1.6% of people have records reflecting hyperhidrosis. About 60% in both databases were women. […] In adolescents and young adults, an incidence rate of 0.6-1% is reported for hyperhidrosis. […] Palmoplantar hyperhidrosis occurs 20 times more frequently in the Japanese than in any other ethnic group. […] All races can be affected by hyperhidrosis; however, Japanese are reportedly affected more than 20 times more frequently than other ethnic groups. […] Both sexes can be affected by hyperhidrosis. […] Persons of all ages can be affected by hyperhidrosis. Localized hyperhidrosis, unlike generalized hyperhidrosis, usually begins in childhood or adolescence. In a study of 850 patients with palmar, axillary, or facial hyperhidrosis, 62% of patients reported that sweating began since before they could remember; 33%, since puberty; and 5%, during adulthood.

• #1 Epidemiology of Primary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/epidemiology-of-primary-hyperhidrosis.html

  Results showed that the prevalence of hyperhidrosis in the U.S. was 2.8% (7.8 million Americans). […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating. […] A series of studies on patients treated by endoscopic thoracic sympathectomy (ETS) reported a family history in 35% and 56% of participants. […] A study of the familial aggregation of hyperhidrosis also suggested that the disorder may be more common than previously thought. […] Focal primary hyperhidrosis has an onset during childhood or adolescence. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] In 2016, results from 1,985 survey participants showed that axillary hyperhidrosis was the most prevalent type of hyperhidrosis in the study sample (68%) followed by palmar (65%) and plantar (64%). […] It should be noted here, again, the primary focal Hh is most typically a multifocal disease. […] Key take-aways: primary Hh is relatively common, multifocal, and chronic with an onset in youth and an apparent genetic link — yet, diagnosis and treatment is often delayed for years.

• #1 Pathophysiology of hyperhidrosis – Choe – Shanghai Chest

  https://shc.amegroups.org/article/view/5204/html

  Primary hyperhidrosis is a pathologic condition that is characterized by excessive sweating beyond the physiological needs required for thermoregulation. It affects 0.65% of the world population and inflicts a significant impact on the quality of life in affected patients. […] Primary hyperhidrosis affects 0.65% of the world population and affects men and women equally. […] The exact pathophysiology of hyperhidrosis remains largely unclear. Most epidemiological studies have shown the existence of a familial trait for primary hyperhidrosis, as 44% to 66% of patients share a positive family history. […] A recent systematic review on the etiology of primary hyperhidrosis by Hashmonai et al. describe three main lines for future research, in order to delineate the pathophysiology of primary hyperhidrosis: genetics, histological observations and enzymatic studies. […] Primary hyperhidrosis is a neurogenic disorder that is characterized by excessive sweating in certain areas of the body, including axillae and palmar surfaces of hands and feet, resulting from an increased activity of sympathetic cholinergic sudomotor nerves.

• #1 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Hyperhidrosis affects 1% to 3% of the U.S. population, yet less than one-half of those affected discuss this with their physician. More than 90% of hyperhidrosis cases are primary, and more than one-half of these cases affect the axillae. More than one-third of persons with axillary hyperhidrosis report that the condition is barely tolerable or completely intolerable, and it nearly always interferes with daily activities. Up to two-thirds of patients report a family history, suggesting a genetic predisposition. Although prevalence between sexes is roughly equal, women are more likely to report hyperhidrosis to their physician. […] Hyperhidrosis negatively impacts daily life, especially emotional well-being, self-esteem, interpersonal relationships, and occupational productivity. Although several tools have been developed to measure the impact of hyperhidrosis on quality of life, most are too complex to incorporate into office practice. The Hyperhidrosis Disease Severity Scale (HDSS) is a validated single-question survey with four grades of tolerability of sweating and impact on quality of life. This survey can estimate the effect on daily activities and response to treatment.

• #1

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6326708/

  To determine the prevalence of primary hyperhidrosis in the city of Botucatu, Brazil, and to evaluate how this disorder affects the quality of life in those suffering from it. […] Excessive sweating was reported by 85 residents (prevalence = 2.07%), of whom 51 (60%) were female. […] Of the 23 subjects diagnosed with primary hyperhidrosis, 11 (48%) reported poor or very poor quality of life. […] Although the prevalence of self-reported excessive sweating was greater than 2%, the actual prevalence of primary hyperhidrosis in our sample was 0.93% and nearly 50% of the respondents with primary hyperhidrosis reported impaired quality of life. […] Data on the prevalence of hyperhidrosis are quite scarce in the medical literature. […] In our study, the prevalence of hyperhidrosis after the application of a questionnaire by trained interviewers was above 2%, as observed by Strutton et al. […] Therefore, after medical evaluation, the estimated prevalence of PH decreased to less than 1%. […] We conclude that the estimated prevalence of PH is near 1%, small in comparison with the number of subjects who report excessive sweating. The disorder affects the QoL in nearly 50% of subjects.

• #1 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281

  Data showed that multifocal hyperhidrosis is common with 81% of patients reporting three or more hyperhidrotic sites. […] Data presented as an abstract on „pediatric breaking news” showed that 17.1% of teens surveyed experience excessive, uncontrollable sweating based on published diagnostic criteria. […] Hyperhidrosis (extreme, uncontrollable sweating affecting 4.8% of people) is often misunderstood, misrepresented and mismanaged, but for the past 15 years the International Hyperhidrosis Society has been bringing the full range of stakeholders to the table to transform missed opportunities into an impactful mission. […] 85% waiting 3+ years to discuss excessive sweating with an HCP and 50% waiting 10+ years to do so. […] 27% never receiving diagnosis. […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating.

• #1 Hyperhidrosis and Its Impact on Those Living With It

  https://www.ajmc.com/view/hyperhidrosis-and-its-impact–on-those-living-with-it

  Some literature suggests a possible racial difference in the prevalence of primary hyperhidrosis, with more Japanese American patients affected by hyperhidrosis in the palms and soles. […] Hyperhidrosis negatively affects QOL and, as such, numerous QOL assessment tools are used to evaluate the condition. […] To date, many QOL impact studies have been completed outside of the United States, but it is likely the results represent QOL in US patients. […] The International Hyperhidrosis Society (IHHS) reports that those with hyperhidrosis have a 300% greater risk of skin infections than those not experiencing the disease. […] Approximately 15.3 million Americans are impacted by hyperhidrosis. […] Hyperhidrosis impairs emotional, mental, and professional facets of living, leading to a significantly decreased QOL. […] It is imperative that healthcare practitioners understand the epidemiology and impact this disease has on individuals.

• #1 Hyperhidrosis Market Size, Share | Industry Forecast, 2034

  https://www.imarcgroup.com/hyperhidrosis-market

  The 7 major hyperhidrosis markets reached a value of US$ 426.7 Million in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 651.2 Million by 2034, exhibiting a growth rate (CAGR) of 3.92% during 2024-2034. […] Hyperhidrosis affects at least 176 million people globally. […] The prevalence of hyperhidrosis is approximately 15.3 million people in the US population. […] The prevalence rate is 2.1% among children and adolescents and people 65 years of age and beyond, with the largest rates occurring in the 18-39 age group (8.8%). […] In India, hyperhidrosis affects about 2.5-3 percent of the population.

• #1 Hyperhidrosis Limits Patients’ Daily Functioning, Quality of Life Across Several Different Regions

  https://www.consultantlive.com/view/hyperhidrosis-limits-patients-daily-functioning-quality-of-life-across-several-different-regions

  In this recent analysis of hyperhidrosis burden on patients, prevalence of the condition and its impacts on patients demonstrate the value of exploring knowledge gaps for this disease. […] The disease known as hyperhidrosis a chronic skin condition known to cause excessive sweating can result in significant psychological, physical, and economic burden for patients daily lives across several different regions, according to new findings, and its prevalence varies substantially across different populations. […] Little is known about the epidemiology and burden of hyperhidrosis across regions to date, Ikoma and colleagues wrote. Therefore, the objective of the project was to gather current evidence on the burden of hyperhidrosis by conducting targeted literature reviews (TLR) on epidemiology, and the human and economic burden posed on patients with this condition.

• #1 Primary focal hyperhidrosis – UpToDate

  https://www.uptodate.com/contents/primary-focal-hyperhidrosis

  Hyperhidrosis (excessive sweating) is a common condition rarely due to significant underlying pathology that may have serious social, emotional, and professional consequences. […] Hyperhidrosis is the secretion of sweat in amounts greater than physiologically needed for thermoregulation. It is most commonly a chronic idiopathic (primary) condition; however, secondary medical conditions or medications should be excluded. Idiopathic hyperhidrosis localized to certain areas of the body is called primary focal hyperhidrosis. Primary focal hyperhidrosis usually affects the axillae, palms, and soles. The condition may also affect other sites, such as the face, scalp, inguinal, and inframammary areas. […] A consensus panel suggested the following diagnostic criteria for primary focal hyperhidrosis: Focal, visible, excessive sweating of at least six months duration without apparent cause.

• #1 Hyperhidrosis Disease Burden Requires Further Understanding

  https://www.dermatologytimes.com/view/hyperhidrosis-disease-burden-requires-further-understanding

  The cost of hospitalizations was found to be the highest in terms of economic burden of direct costs. […] Future actions should include implementation of educational programs for physicians, medical specialists, and patients to raise awareness of the condition; the conduct of further studies with larger scope and bigger patient populations; and the generation of more evidence for Japan, concluded the authors.

• #1 Epidemiology of Hyperhidrosis in Danish Blood Donors | HTML | Acta Dermato-Venereologica

  https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3790

  This retrospective cohort study found that the prevalence of self-reported HH in blood donors was in line with previous reports. The prevalence of hospital-diagnosed HH was lower than previously reported. This may be the result of selection bias, as blood donors are implicitly healthy and have fewer diagnoses than the general population, or that individuals with hospital-diagnosed HH were receiving medications that precluded blood donation and thus study participation. […] We speculate that several factors contribute to the differences in prevalence, lifestyle habits, SES and income between self-reported and hospital-diagnosed HH. Firstly, low awareness of HH in the public, the stigma surrounding excessive sweating and seeking help for sweating, and the notion that treatments are futile lead to most adults with HH not seeking medical help for sweating. Next, lack of awareness of diagnostics and treatments for HH in physicians, and the seemingly benign symptomatology of HH, lead to many who seek help for HH not being given adequate treatment or referred to dermatologists.

• #2 SciELO Brasil – Hyperhidrosis: prevalence and impact on quality of life Hyperhidrosis: prevalence and impact on quality of life

  https://www.scielo.br/j/jbpneu/a/gxS3VxQSW3j7hX5MkLXDxqz/

  Objective: To determine the prevalence of primary hyperhidrosis in the city of Botucatu, Brazil, and to evaluate how this disorder affects the quality of life in those suffering from it. […] A total of 4,133 residents, in 1,351 households, were surveyed. Excessive sweating was reported by 85 residents (prevalence = 2.07%), of whom 51 (60%) were female. […] Although the prevalence of self-reported excessive sweating was greater than 2%, the actual prevalence of primary hyperhidrosis in our sample was 0.93% and nearly 50% of the respondents with primary hyperhidrosis reported impaired quality of life. […] There are few data on the worldwide prevalence of hyperhidrosis, reported values ranging from 0.072% to 9%. […] In our study, the prevalence of hyperhidrosis after the application of a questionnaire by trained interviewers was above 2%, as observed by Strutton et al. However, after medical evaluation, 25% of the patients that reported excessive sweating actually showed normal sweating and 30% had SH. Consequently, more than half of the subjects that reported excessive sweating did not actually have PH. Therefore, after medical evaluation, the estimated prevalence of PH decreased to less than 1%.

• #2 Epidemiology of Primary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/epidemiology-of-primary-hyperhidrosis.html

  In the past, there was little data on the prevalence of primary hyperhidrosis (Hh). Recently, however, more studies have been published in the medical literature – with illuminating statistics: […] Researchers reported the prevalence of hyperhidrosis in the United States as 4.8%, representing approximately 15.3 million people. […] A study showed that, in Sweden, prevalence of primary hyperhidrosis was 5.5% with severe, primary hyperhidrosis affecting 1.4% of the population. […] Research results found that the prevalence of primary hyperhidrosis among dermatology outpatients in Shanghai was 14.5% and in Vancouver was 12.3%. […] Data showed that multifocal hyperhidrosis is common with 81% of patients reporting three or more hyperhidrotic sites. […] Data presented as an abstract on „pediatric breaking news” showed that 17.1% of teens surveyed experience excessive, uncontrollable sweating based on published diagnostic criteria.

• #2 Hyperhidrosis and Its Impact on Those Living With It

  https://www.ajmc.com/view/hyperhidrosis-and-its-impact–on-those-living-with-it

  Some literature suggests a possible racial difference in the prevalence of primary hyperhidrosis, with more Japanese American patients affected by hyperhidrosis in the palms and soles. […] Hyperhidrosis negatively affects QOL and, as such, numerous QOL assessment tools are used to evaluate the condition. […] To date, many QOL impact studies have been completed outside of the United States, but it is likely the results represent QOL in US patients. […] The International Hyperhidrosis Society (IHHS) reports that those with hyperhidrosis have a 300% greater risk of skin infections than those not experiencing the disease. […] Approximately 15.3 million Americans are impacted by hyperhidrosis. […] Hyperhidrosis impairs emotional, mental, and professional facets of living, leading to a significantly decreased QOL. […] It is imperative that healthcare practitioners understand the epidemiology and impact this disease has on individuals.

• #2 Epidemiology of hyperhidrosis in 2 population-based health care databases – EM consulte

  https://www.em-consulte.com/es/article/1193840/resume/epidemiology-of-hyperhidrosis-in-2-population-base

  Epidemiology of hyperhidrosis in 2 population-based health care databases – 13/01/18 […] Population-based and clinical case reports of hyperhidrosis (HH) provide prevalence estimates that vary widely across reported studies because of differences in case ascertainment. […] In this study, we specify diagnostic, symptom, and prescription codes for HH to estimate incidence and prevalence for the United Kingdom and the United States. […] Data from UK and US health care databases were analyzed to ascertain HH cases and estimate incidence and prevalence from health care records during calendar years 2011 through 2013. […] On the basis of 2013 data for the United States and United Kingdom, between 1.0% and 1.6% of these populations have health care records indicating diagnosis or treatment of HH. Women accounted for approximately 60% of incident and prevalent cases in both databases. […] The findings represent a plausible estimate for incidence and prevalence of HH among persons seeking medical care for excessive sweating. Improved practices for identifying HH in clinical settings may increase the sensitivity and specificity of future studies and improve characterization and quantification of the population burden of this significant disease.

• #2 Hyperhidrosis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/1073359-overview

  In the United States and the United Kingdom, 1-1.6% of people have records reflecting hyperhidrosis. About 60% in both databases were women. […] In adolescents and young adults, an incidence rate of 0.6-1% is reported for hyperhidrosis. […] Palmoplantar hyperhidrosis occurs 20 times more frequently in the Japanese than in any other ethnic group. […] All races can be affected by hyperhidrosis; however, Japanese are reportedly affected more than 20 times more frequently than other ethnic groups. […] Both sexes can be affected by hyperhidrosis. […] Persons of all ages can be affected by hyperhidrosis. Localized hyperhidrosis, unlike generalized hyperhidrosis, usually begins in childhood or adolescence. In a study of 850 patients with palmar, axillary, or facial hyperhidrosis, 62% of patients reported that sweating began since before they could remember; 33%, since puberty; and 5%, during adulthood.

• #2 Epidemiology of Primary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/epidemiology-of-primary-hyperhidrosis.html

  Results showed that the prevalence of hyperhidrosis in the U.S. was 2.8% (7.8 million Americans). […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating. […] A series of studies on patients treated by endoscopic thoracic sympathectomy (ETS) reported a family history in 35% and 56% of participants. […] A study of the familial aggregation of hyperhidrosis also suggested that the disorder may be more common than previously thought. […] Focal primary hyperhidrosis has an onset during childhood or adolescence. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] In 2016, results from 1,985 survey participants showed that axillary hyperhidrosis was the most prevalent type of hyperhidrosis in the study sample (68%) followed by palmar (65%) and plantar (64%). […] It should be noted here, again, the primary focal Hh is most typically a multifocal disease. […] Key take-aways: primary Hh is relatively common, multifocal, and chronic with an onset in youth and an apparent genetic link — yet, diagnosis and treatment is often delayed for years.

• #2 Primary focal hyperhidrosis – UpToDate

  https://www.uptodate.com/contents/primary-focal-hyperhidrosis

  Hyperhidrosis (excessive sweating) is a common condition rarely due to significant underlying pathology that may have serious social, emotional, and professional consequences. […] Hyperhidrosis is the secretion of sweat in amounts greater than physiologically needed for thermoregulation. It is most commonly a chronic idiopathic (primary) condition; however, secondary medical conditions or medications should be excluded. Idiopathic hyperhidrosis localized to certain areas of the body is called primary focal hyperhidrosis. Primary focal hyperhidrosis usually affects the axillae, palms, and soles. The condition may also affect other sites, such as the face, scalp, inguinal, and inframammary areas. […] A consensus panel suggested the following diagnostic criteria for primary focal hyperhidrosis: Focal, visible, excessive sweating of at least six months duration without apparent cause.

• #2 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Hyperhidrosis affects 1% to 3% of the U.S. population, yet less than one-half of those affected discuss this with their physician. More than 90% of hyperhidrosis cases are primary, and more than one-half of these cases affect the axillae. More than one-third of persons with axillary hyperhidrosis report that the condition is barely tolerable or completely intolerable, and it nearly always interferes with daily activities. Up to two-thirds of patients report a family history, suggesting a genetic predisposition. Although prevalence between sexes is roughly equal, women are more likely to report hyperhidrosis to their physician. […] Hyperhidrosis negatively impacts daily life, especially emotional well-being, self-esteem, interpersonal relationships, and occupational productivity. Although several tools have been developed to measure the impact of hyperhidrosis on quality of life, most are too complex to incorporate into office practice. The Hyperhidrosis Disease Severity Scale (HDSS) is a validated single-question survey with four grades of tolerability of sweating and impact on quality of life. This survey can estimate the effect on daily activities and response to treatment.

• #2 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281

  Data showed that multifocal hyperhidrosis is common with 81% of patients reporting three or more hyperhidrotic sites. […] Data presented as an abstract on „pediatric breaking news” showed that 17.1% of teens surveyed experience excessive, uncontrollable sweating based on published diagnostic criteria. […] Hyperhidrosis (extreme, uncontrollable sweating affecting 4.8% of people) is often misunderstood, misrepresented and mismanaged, but for the past 15 years the International Hyperhidrosis Society has been bringing the full range of stakeholders to the table to transform missed opportunities into an impactful mission. […] 85% waiting 3+ years to discuss excessive sweating with an HCP and 50% waiting 10+ years to do so. […] 27% never receiving diagnosis. […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating.

• #2

  https://www.termedia.pl/Hyperhidrosis-disease-aetiology-classification-and-r-nmanagement-in-the-light-of-modern-treatment-modalities,7,46948,1,1.html

  The aetiology of excessive perspiration can be either primary or secondary to the systemic diseases. […] Hyperhidrosis has also a direct effect on skin condition by interfering with its natural protective mechanisms. This results in a greater prevalence of dermatoses among affected patients, especially of fungal, bacterial and less often viral origin. […] Nevertheless, the epidemiological studies conducted among large population in the United States of America and Canada estimated the global prevalence of primary hyperhidrosis equally at about 2.0-3.0% for men and women. […] Stefaniak et al. performed a research among Polish medical and dentistry students and discovered that the occurrence of hyperhidrosis reached up to 8.0% of the study group. […] A typical onset of symptoms is usually observed in individuals aged 14-25 years and their intensity mostly reduces with time.

• #2 Hyperhidrosis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034

  https://www.researchandmarkets.com/reports/5969816/hyperhidrosis-market-epidemiology-industry?srsltid=AfmBOoqchShHR2qXfHwIyUxSQk2C_ZTVoFwsqTYfPb0IQfOUOoKsOJwp

  This report provides an exhaustive analysis of the hyperhidrosis market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. […] According to the report the United States has the largest patient pool for hyperhidrosis and also represents the largest market for its treatment. […] This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the hyperhidrosis market in any manner. […] What is the number of prevalent cases (2018-2034) of hyperhidrosis across the seven major markets? […] What are the key factors driving the epidemiological trend of hyperhidrosis? […] What will be the growth rate of patients across the seven major markets?

• #2 Hyperhidrosis Limits Patients’ Daily Functioning, Quality of Life Across Several Different Regions

  https://www.hcplive.com/view/hyperhidrosis-limits-patients-daily-functioning-quality-of-life-across-several-different-regions

  In this recent analysis of hyperhidrosis burden on patients, prevalence of the condition and its impacts on patients demonstrate the value of exploring knowledge gaps for this disease. […] The disease known as hyperhidrosis, a chronic skin condition known to cause excessive sweating, can result in significant psychological, physical, and economic burden for patients’ daily lives across several different regions, according to new findings, and its prevalence varies substantially across different populations. […] Little is known about the epidemiology and burden of hyperhidrosis across regions to date, Ikoma and colleagues wrote. Therefore, the objective of the project was to gather current evidence on the burden of hyperhidrosis by conducting targeted literature reviews (TLR) on epidemiology, and the human and economic burden posed on patients with this condition.

• #2 Hyperhidrosis Disease Burden Requires Further Understanding

  https://www.dermatologytimes.com/view/hyperhidrosis-disease-burden-requires-further-understanding

  The cost of hospitalizations was found to be the highest in terms of economic burden of direct costs. […] Future actions should include implementation of educational programs for physicians, medical specialists, and patients to raise awareness of the condition; the conduct of further studies with larger scope and bigger patient populations; and the generation of more evidence for Japan, concluded the authors.

• #2 Epidemiology of Hyperhidrosis in Danish Blood Donors | HTML | Acta Dermato-Venereologica

  https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3790

  This retrospective cohort study found that the prevalence of self-reported HH in blood donors was in line with previous reports. The prevalence of hospital-diagnosed HH was lower than previously reported. This may be the result of selection bias, as blood donors are implicitly healthy and have fewer diagnoses than the general population, or that individuals with hospital-diagnosed HH were receiving medications that precluded blood donation and thus study participation. […] We speculate that several factors contribute to the differences in prevalence, lifestyle habits, SES and income between self-reported and hospital-diagnosed HH. Firstly, low awareness of HH in the public, the stigma surrounding excessive sweating and seeking help for sweating, and the notion that treatments are futile lead to most adults with HH not seeking medical help for sweating. Next, lack of awareness of diagnostics and treatments for HH in physicians, and the seemingly benign symptomatology of HH, lead to many who seek help for HH not being given adequate treatment or referred to dermatologists.

• #3 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281

  In the past, there was little data on the prevalence of primary hyperhidrosis (Hh). Recently, however, more studies have been published in the medical literature – with illuminating statistics: […] Researchers reported the prevalence of hyperhidrosis in the United States as 4.8%, representing approximately 15.3 million people. That’s almost twice as many people as previously believed and this makes Hh more common than autism, melanoma, psoriasis, and peanut allergies. […] A study showed that, in Sweden, prevalence of primary hyperhidrosis was 5.5% with severe, primary hyperhidrosis affecting 1.4% of the population. Secondary hyperhidrosis was observed in 14.8% of the study participants. […] Research results found that the prevalence of primary hyperhidrosis among dermatology outpatients in Shanghai was 14.5% and in Vancouver was 12.3%.

• #3 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Hyperhidrosis-Prognosis-and-Epidemiology.aspx

  Hyperhidrosis refers to excessive sweating that does not necessarily occur in response to the body becoming overheated by exercise or a hot environment, for example. […] It is difficult to say how many people develop hyperhidrosis as there are no guidelines to determine exactly what constitutes normal sweating, but estimates suggest that the worldwide prevalence is between 2% and 4%, without any particular gender predisposition. […] There are differences in prevalence globally, with one study, for example, having shown a prevalence of 2.9% in the US and up to 5.0% prevalence in certain areas of China.

• #3 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Hyperhidrosis affects 1% to 3% of the U.S. population, yet less than one-half of those affected discuss this with their physician. More than 90% of hyperhidrosis cases are primary, and more than one-half of these cases affect the axillae. More than one-third of persons with axillary hyperhidrosis report that the condition is barely tolerable or completely intolerable, and it nearly always interferes with daily activities. Up to two-thirds of patients report a family history, suggesting a genetic predisposition. Although prevalence between sexes is roughly equal, women are more likely to report hyperhidrosis to their physician. […] Hyperhidrosis negatively impacts daily life, especially emotional well-being, self-esteem, interpersonal relationships, and occupational productivity. Although several tools have been developed to measure the impact of hyperhidrosis on quality of life, most are too complex to incorporate into office practice. The Hyperhidrosis Disease Severity Scale (HDSS) is a validated single-question survey with four grades of tolerability of sweating and impact on quality of life. This survey can estimate the effect on daily activities and response to treatment.

• #3 Hyperhidrosis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/1073359-overview

  In the United States and the United Kingdom, 1-1.6% of people have records reflecting hyperhidrosis. About 60% in both databases were women. […] In adolescents and young adults, an incidence rate of 0.6-1% is reported for hyperhidrosis. […] Palmoplantar hyperhidrosis occurs 20 times more frequently in the Japanese than in any other ethnic group. […] All races can be affected by hyperhidrosis; however, Japanese are reportedly affected more than 20 times more frequently than other ethnic groups. […] Both sexes can be affected by hyperhidrosis. […] Persons of all ages can be affected by hyperhidrosis. Localized hyperhidrosis, unlike generalized hyperhidrosis, usually begins in childhood or adolescence. In a study of 850 patients with palmar, axillary, or facial hyperhidrosis, 62% of patients reported that sweating began since before they could remember; 33%, since puberty; and 5%, during adulthood.

• #3 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281

  Data showed that multifocal hyperhidrosis is common with 81% of patients reporting three or more hyperhidrotic sites. […] Data presented as an abstract on „pediatric breaking news” showed that 17.1% of teens surveyed experience excessive, uncontrollable sweating based on published diagnostic criteria. […] Hyperhidrosis (extreme, uncontrollable sweating affecting 4.8% of people) is often misunderstood, misrepresented and mismanaged, but for the past 15 years the International Hyperhidrosis Society has been bringing the full range of stakeholders to the table to transform missed opportunities into an impactful mission. […] 85% waiting 3+ years to discuss excessive sweating with an HCP and 50% waiting 10+ years to do so. […] 27% never receiving diagnosis. […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating.

• #3 Hyperhidrosis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hyperhidrosis/symptoms-causes/syc-20367152

  Hyperhidrosis (hi-pur-hi-DROE-sis) is excessive sweating that’s not always related to heat or exercise. Heavy sweating can disrupt your day and cause social anxiety and embarrassment. […] Hyperhidrosis treatment usually helps. […] Primary hyperhidrosis is caused by faulty nerve signals that trigger eccrine sweat glands to become overactive. It usually affects the palms, soles, underarms and sometimes the face. […] There is no medical cause for this type of hyperhidrosis. It can run in families. […] Secondary hyperhidrosis is caused by an underlying medical condition or by taking certain medications, such as pain relievers, antidepressants, and some diabetes and hormonal medications. […] Risk factors for hyperhidrosis include: Having a blood relative, such as a parent, sibling or grandparent, who sweats heavily. […] Complications of hyperhidrosis include: People who sweat a lot are more prone to skin infections. […] Your condition may affect your pursuit of work and educational goals.

• #3 Hyperhidrosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459227/

  Hyperhidrosis affects approximately 3% of the United States population and is most common in patients between 20 to 60 years of age. No evidence shows that either men or women are at increased risk. The palmar region is the most commonly affected area. Hyperhidrosis affects all races, but data show that the Japanese are more affected than any other ethnic group. […] Studies have shown that the prevalence of this disorder is approximately 3% in the United States. Hyperhidrosis can result in emotional, psychological, social, and occupational impairment.

• #3 Primary hyperhidrosis prevalence and characteristics among medical students in Rio de Janeiro | PLOS One

  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220664

  Hyperhidrosis is a pathological condition defined by excessive sweating beyond thermoregulatory physiological needs, which can cause substantial psychological impact and impairment of daily activities. […] PH prevalence among Rio de Janeiro medical students was 20.56%, similar between men and women, predominating associated presentations, axillary, palmar and plantar sites, strong familial history, age of onset before 18 years, and some degree of life impairment. […] PH prevalence, however, is poorly verified. […] Our 20.56% PH prevalence finding was higher than those of the studies also among medical students in Aracaju, Brazil (14.76%) […] We found strong association between family history of PH and occurrence of the disease, with a prevalence ratio of 4.27. […] Our study has shown 86.84% of PH participants reported some degree of impact on quality of life.

• #3 Epidemiology of Hyperhidrosis in Danish Blood Donors | HTML | Acta Dermato-Venereologica

  https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3790

  Epidemiology of Hyperhidrosis in Danish Blood Donors […] The objectives of this retrospective cohort study were to estimate the prevalence of hyperhidrosis and to compare demographic, lifestyle, and socioeconomic parameters in blood donors with and without self-reported or hospital-diagnosed hyperhidrosis. Overall, 2,794 of 30,808 blood donors (9.07%; 95% confidence interval (95% CI) 8.759.40) had self-reported hyperhidrosis and 284 of 122,225 (0.23%; 95% CI 0.210.26) had hospital-diagnosed hyperhidrosis. Self-reported hyperhidrosis was associated with smoking (odds ratio (OR) 1.17; 95% CI 1.051.31), overweight (OR 1.72; 95% CI 1.581.87), unemployed (OR 1.60; 95% CI 1.242.08), short education (OR 0.76; 95% CI 0.640.90), and lower income (beta-coefficient 26,121; 95% CI 37,931, 14,311). Hospital-diagnosed hyperhidrosis did not differ from controls. Thus, self-reported hyperhidrosis was associated with potential hyperhidrosis risk factors (smoking, overweight) and disease implications (unemployment, low education level and income).

• #3 Hyperhidrosis Disease Burden Requires Further Understanding

  https://www.dermatologytimes.com/view/hyperhidrosis-disease-burden-requires-further-understanding

  The cost of hospitalizations was found to be the highest in terms of economic burden of direct costs. […] Future actions should include implementation of educational programs for physicians, medical specialists, and patients to raise awareness of the condition; the conduct of further studies with larger scope and bigger patient populations; and the generation of more evidence for Japan, concluded the authors.

• #3 SciELO Brasil – Hyperhidrosis: prevalence and impact on quality of life Hyperhidrosis: prevalence and impact on quality of life

  https://www.scielo.br/j/jbpneu/a/gxS3VxQSW3j7hX5MkLXDxqz/

  Objective: To determine the prevalence of primary hyperhidrosis in the city of Botucatu, Brazil, and to evaluate how this disorder affects the quality of life in those suffering from it. […] A total of 4,133 residents, in 1,351 households, were surveyed. Excessive sweating was reported by 85 residents (prevalence = 2.07%), of whom 51 (60%) were female. […] Although the prevalence of self-reported excessive sweating was greater than 2%, the actual prevalence of primary hyperhidrosis in our sample was 0.93% and nearly 50% of the respondents with primary hyperhidrosis reported impaired quality of life. […] There are few data on the worldwide prevalence of hyperhidrosis, reported values ranging from 0.072% to 9%. […] In our study, the prevalence of hyperhidrosis after the application of a questionnaire by trained interviewers was above 2%, as observed by Strutton et al. However, after medical evaluation, 25% of the patients that reported excessive sweating actually showed normal sweating and 30% had SH. Consequently, more than half of the subjects that reported excessive sweating did not actually have PH. Therefore, after medical evaluation, the estimated prevalence of PH decreased to less than 1%.

• #4

  http://umu.diva-portal.org/smash/record.jsf?pid=diva2:1192575

  Primary hyperhidrosis, excessive sweating, is a condition with unknown prevalence in many parts of the world. […] Our results showed that primary hyperhidrosis occurs in 5.5% of the Swedish population. The disease reduces quality of life and affects mainly the psychological health of the individuals. […] The prevalence of primary hyperhidrosis was 5.5%, and severe primary hyperhidrosis (HDSS 3-4 points) occurred in 1.4%. […] Hyperhidrosis affects individuals in adolescence as a focal form while occurring as a generalised form with increasing age. Further, the prevalence of primary hyperhidrosis described in our study is comparable to other studies from the western hemisphere. […] Primary hyperhidrosis mainly impairs mental rather than physical aspects of life and also interferes with specific daily activities of the affected individuals. […] Primary hyperhidrosis reduces quality of life and interferes with daily activities of those affected.

• #4

  https://www.termedia.pl/Hyperhidrosis-disease-aetiology-classification-and-r-nmanagement-in-the-light-of-modern-treatment-modalities,7,46948,1,1.html

  The aetiology of excessive perspiration can be either primary or secondary to the systemic diseases. […] Hyperhidrosis has also a direct effect on skin condition by interfering with its natural protective mechanisms. This results in a greater prevalence of dermatoses among affected patients, especially of fungal, bacterial and less often viral origin. […] Nevertheless, the epidemiological studies conducted among large population in the United States of America and Canada estimated the global prevalence of primary hyperhidrosis equally at about 2.0-3.0% for men and women. […] Stefaniak et al. performed a research among Polish medical and dentistry students and discovered that the occurrence of hyperhidrosis reached up to 8.0% of the study group. […] A typical onset of symptoms is usually observed in individuals aged 14-25 years and their intensity mostly reduces with time.

• #4 Hyperhidrosis

  https://mobile.fpnotebook.com/Derm/Sweat/Hyprhdrs.htm

  Prevalence: 1-3% of U.S. […] Both genders affected equally (women report more often)

• #4 Hyperhidrosis Market Size, Share | Industry Forecast, 2034

  https://www.imarcgroup.com/hyperhidrosis-market

  The 7 major hyperhidrosis markets reached a value of US$ 426.7 Million in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 651.2 Million by 2034, exhibiting a growth rate (CAGR) of 3.92% during 2024-2034. […] Hyperhidrosis affects at least 176 million people globally. […] The prevalence of hyperhidrosis is approximately 15.3 million people in the US population. […] The prevalence rate is 2.1% among children and adolescents and people 65 years of age and beyond, with the largest rates occurring in the 18-39 age group (8.8%). […] In India, hyperhidrosis affects about 2.5-3 percent of the population.

• #4 Epidemiology of Primary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/epidemiology-of-primary-hyperhidrosis.html

  Results showed that the prevalence of hyperhidrosis in the U.S. was 2.8% (7.8 million Americans). […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating. […] A series of studies on patients treated by endoscopic thoracic sympathectomy (ETS) reported a family history in 35% and 56% of participants. […] A study of the familial aggregation of hyperhidrosis also suggested that the disorder may be more common than previously thought. […] Focal primary hyperhidrosis has an onset during childhood or adolescence. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] In 2016, results from 1,985 survey participants showed that axillary hyperhidrosis was the most prevalent type of hyperhidrosis in the study sample (68%) followed by palmar (65%) and plantar (64%). […] It should be noted here, again, the primary focal Hh is most typically a multifocal disease. […] Key take-aways: primary Hh is relatively common, multifocal, and chronic with an onset in youth and an apparent genetic link — yet, diagnosis and treatment is often delayed for years.

• #4 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281

  In the past, there was little data on the prevalence of primary hyperhidrosis (Hh). Recently, however, more studies have been published in the medical literature – with illuminating statistics: […] Researchers reported the prevalence of hyperhidrosis in the United States as 4.8%, representing approximately 15.3 million people. That’s almost twice as many people as previously believed and this makes Hh more common than autism, melanoma, psoriasis, and peanut allergies. […] A study showed that, in Sweden, prevalence of primary hyperhidrosis was 5.5% with severe, primary hyperhidrosis affecting 1.4% of the population. Secondary hyperhidrosis was observed in 14.8% of the study participants. […] Research results found that the prevalence of primary hyperhidrosis among dermatology outpatients in Shanghai was 14.5% and in Vancouver was 12.3%.

• #4 Epidemiology of Primary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/epidemiology-of-primary-hyperhidrosis.html

  In the past, there was little data on the prevalence of primary hyperhidrosis (Hh). Recently, however, more studies have been published in the medical literature – with illuminating statistics: […] Researchers reported the prevalence of hyperhidrosis in the United States as 4.8%, representing approximately 15.3 million people. […] A study showed that, in Sweden, prevalence of primary hyperhidrosis was 5.5% with severe, primary hyperhidrosis affecting 1.4% of the population. […] Research results found that the prevalence of primary hyperhidrosis among dermatology outpatients in Shanghai was 14.5% and in Vancouver was 12.3%. […] Data showed that multifocal hyperhidrosis is common with 81% of patients reporting three or more hyperhidrotic sites. […] Data presented as an abstract on „pediatric breaking news” showed that 17.1% of teens surveyed experience excessive, uncontrollable sweating based on published diagnostic criteria.

• #4 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Hyperhidrosis affects 1% to 3% of the U.S. population, yet less than one-half of those affected discuss this with their physician. More than 90% of hyperhidrosis cases are primary, and more than one-half of these cases affect the axillae. More than one-third of persons with axillary hyperhidrosis report that the condition is barely tolerable or completely intolerable, and it nearly always interferes with daily activities. Up to two-thirds of patients report a family history, suggesting a genetic predisposition. Although prevalence between sexes is roughly equal, women are more likely to report hyperhidrosis to their physician. […] Hyperhidrosis negatively impacts daily life, especially emotional well-being, self-esteem, interpersonal relationships, and occupational productivity. Although several tools have been developed to measure the impact of hyperhidrosis on quality of life, most are too complex to incorporate into office practice. The Hyperhidrosis Disease Severity Scale (HDSS) is a validated single-question survey with four grades of tolerability of sweating and impact on quality of life. This survey can estimate the effect on daily activities and response to treatment.

• #4 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281

  A series of studies on patients treated by endoscopic thoracic sympathectomy (ETS) reported a family history in 35% and 56% of participants. […] A study of the familial aggregation of hyperhidrosis also suggested that the disorder may be more common than previously thought. […] Focal primary hyperhidrosis usually has an onset during childhood or adolescence. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] Key take-aways: primary Hh is relatively common, multifocal, and chronic with an onset in youth and an apparent genetic link — yet, diagnosis and treatment is often delayed for years.

• #4 Epidemiology of Hyperhidrosis in Danish Blood Donors | HTML | Acta Dermato-Venereologica

  https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3790

  The prevalence of hospital-diagnosed HH is clearly lower than the prevalence of self-reported HH. Self-reported HH is associated with potential HH risk factors (i.e. smoking and overweight) and potential disease implications (i.e. unemployment, low education level and income). In contrast, hospital-diagnosed HH does not differ from controls on these parameters.

• #4 Hyperhidrosis Disease Burden Requires Further Understanding

  https://www.dermatologytimes.com/view/hyperhidrosis-disease-burden-requires-further-understanding

  More understanding of the physical, psychological, and economic burdens of hyperhidrosis is needed. […] Hyperhidrosis is a chronic skin condition characterized by excessive sweating, and patients can incur costs that are associated with attempting to manage and hide excessive sweating, which can be embarrassing. […] The incidence of hyperhidrosis fluctuated from 0.13% in the UK to 0.28% in the United States, with a higher rate in female patients. The prevalence ranged from 2.8% to 4.8% in the US general population to 18.4% in Chinese inpatients, whereas the prevalence of axillary hyperhidrosis ranged from 1.4% in the US general population to 5.75% in Japanese employees/students. […] There was little evidence of the hyperhidrosis burden, especially among Japanese patients, but the burden was high and decreased patients daily functioning.

• #4 SciELO Brasil – Hyperhidrosis: prevalence and impact on quality of life Hyperhidrosis: prevalence and impact on quality of life

  https://www.scielo.br/j/jbpneu/a/gxS3VxQSW3j7hX5MkLXDxqz/

  Objective: To determine the prevalence of primary hyperhidrosis in the city of Botucatu, Brazil, and to evaluate how this disorder affects the quality of life in those suffering from it. […] A total of 4,133 residents, in 1,351 households, were surveyed. Excessive sweating was reported by 85 residents (prevalence = 2.07%), of whom 51 (60%) were female. […] Although the prevalence of self-reported excessive sweating was greater than 2%, the actual prevalence of primary hyperhidrosis in our sample was 0.93% and nearly 50% of the respondents with primary hyperhidrosis reported impaired quality of life. […] There are few data on the worldwide prevalence of hyperhidrosis, reported values ranging from 0.072% to 9%. […] In our study, the prevalence of hyperhidrosis after the application of a questionnaire by trained interviewers was above 2%, as observed by Strutton et al. However, after medical evaluation, 25% of the patients that reported excessive sweating actually showed normal sweating and 30% had SH. Consequently, more than half of the subjects that reported excessive sweating did not actually have PH. Therefore, after medical evaluation, the estimated prevalence of PH decreased to less than 1%.

• #4 Epidemiology of hyperhidrosis in 2 population-based health care databases – EM consulte

  https://www.em-consulte.com/es/article/1193840/resume/epidemiology-of-hyperhidrosis-in-2-population-base

  Epidemiology of hyperhidrosis in 2 population-based health care databases – 13/01/18 […] Population-based and clinical case reports of hyperhidrosis (HH) provide prevalence estimates that vary widely across reported studies because of differences in case ascertainment. […] In this study, we specify diagnostic, symptom, and prescription codes for HH to estimate incidence and prevalence for the United Kingdom and the United States. […] Data from UK and US health care databases were analyzed to ascertain HH cases and estimate incidence and prevalence from health care records during calendar years 2011 through 2013. […] On the basis of 2013 data for the United States and United Kingdom, between 1.0% and 1.6% of these populations have health care records indicating diagnosis or treatment of HH. Women accounted for approximately 60% of incident and prevalent cases in both databases. […] The findings represent a plausible estimate for incidence and prevalence of HH among persons seeking medical care for excessive sweating. Improved practices for identifying HH in clinical settings may increase the sensitivity and specificity of future studies and improve characterization and quantification of the population burden of this significant disease.

• #4 Hyperhidrosis and Its Impact on Those Living With It

  https://www.ajmc.com/view/hyperhidrosis-and-its-impact–on-those-living-with-it

  Hyperhidrosis affects approximately 4.8% of Americans. […] Primary hyperhidrosis reportedly affects 4.8% of Americans, or approximately 15.3 million individuals. […] Because it is often underreported and underdiagnosed, the true prevalence rates may be higher. […] The age of onset of primary hyperhidrosis is often between 14 and 25 years. […] It primarily affects younger adults aged 18 to 39 years. […] Rates are lowest among those 65 years and older, young children, and adolescents. […] It is speculated that lower prevalence among the elderly population is due to disease regression over time. […] Incidence rates do not appear to differ between genders. […] However, men may be more likely to be affected in craniofacial areas, although women are more likely to be affected in axillae areas.

• #5 Epidemiology of Primary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/epidemiology-of-primary-hyperhidrosis.html

  In the past, there was little data on the prevalence of primary hyperhidrosis (Hh). Recently, however, more studies have been published in the medical literature – with illuminating statistics: […] Researchers reported the prevalence of hyperhidrosis in the United States as 4.8%, representing approximately 15.3 million people. […] A study showed that, in Sweden, prevalence of primary hyperhidrosis was 5.5% with severe, primary hyperhidrosis affecting 1.4% of the population. […] Research results found that the prevalence of primary hyperhidrosis among dermatology outpatients in Shanghai was 14.5% and in Vancouver was 12.3%. […] Data showed that multifocal hyperhidrosis is common with 81% of patients reporting three or more hyperhidrotic sites. […] Data presented as an abstract on „pediatric breaking news” showed that 17.1% of teens surveyed experience excessive, uncontrollable sweating based on published diagnostic criteria.

• #5 Hyperhidrosis and Its Impact on Those Living With It

  https://www.ajmc.com/view/hyperhidrosis-and-its-impact–on-those-living-with-it

  Hyperhidrosis affects approximately 4.8% of Americans. […] Primary hyperhidrosis reportedly affects 4.8% of Americans, or approximately 15.3 million individuals. […] Because it is often underreported and underdiagnosed, the true prevalence rates may be higher. […] The age of onset of primary hyperhidrosis is often between 14 and 25 years. […] It primarily affects younger adults aged 18 to 39 years. […] Rates are lowest among those 65 years and older, young children, and adolescents. […] It is speculated that lower prevalence among the elderly population is due to disease regression over time. […] Incidence rates do not appear to differ between genders. […] However, men may be more likely to be affected in craniofacial areas, although women are more likely to be affected in axillae areas.

• #5 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281

  A series of studies on patients treated by endoscopic thoracic sympathectomy (ETS) reported a family history in 35% and 56% of participants. […] A study of the familial aggregation of hyperhidrosis also suggested that the disorder may be more common than previously thought. […] Focal primary hyperhidrosis usually has an onset during childhood or adolescence. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] Key take-aways: primary Hh is relatively common, multifocal, and chronic with an onset in youth and an apparent genetic link — yet, diagnosis and treatment is often delayed for years.

• #5 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281

  Data showed that multifocal hyperhidrosis is common with 81% of patients reporting three or more hyperhidrotic sites. […] Data presented as an abstract on „pediatric breaking news” showed that 17.1% of teens surveyed experience excessive, uncontrollable sweating based on published diagnostic criteria. […] Hyperhidrosis (extreme, uncontrollable sweating affecting 4.8% of people) is often misunderstood, misrepresented and mismanaged, but for the past 15 years the International Hyperhidrosis Society has been bringing the full range of stakeholders to the table to transform missed opportunities into an impactful mission. […] 85% waiting 3+ years to discuss excessive sweating with an HCP and 50% waiting 10+ years to do so. […] 27% never receiving diagnosis. […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating.

• #5 Hyperhidrosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459227/

  Hyperhidrosis affects approximately 3% of the United States population and is most common in patients between 20 to 60 years of age. No evidence shows that either men or women are at increased risk. The palmar region is the most commonly affected area. Hyperhidrosis affects all races, but data show that the Japanese are more affected than any other ethnic group. […] Studies have shown that the prevalence of this disorder is approximately 3% in the United States. Hyperhidrosis can result in emotional, psychological, social, and occupational impairment.

• #5 Epidemiology of Primary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/epidemiology-of-primary-hyperhidrosis.html

  Results showed that the prevalence of hyperhidrosis in the U.S. was 2.8% (7.8 million Americans). […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating. […] A series of studies on patients treated by endoscopic thoracic sympathectomy (ETS) reported a family history in 35% and 56% of participants. […] A study of the familial aggregation of hyperhidrosis also suggested that the disorder may be more common than previously thought. […] Focal primary hyperhidrosis has an onset during childhood or adolescence. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] In 2016, results from 1,985 survey participants showed that axillary hyperhidrosis was the most prevalent type of hyperhidrosis in the study sample (68%) followed by palmar (65%) and plantar (64%). […] It should be noted here, again, the primary focal Hh is most typically a multifocal disease. […] Key take-aways: primary Hh is relatively common, multifocal, and chronic with an onset in youth and an apparent genetic link — yet, diagnosis and treatment is often delayed for years.

• #5 Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis

  Our understanding of the international prevalence, clinical characteristics, and patient burden of primary hyperhidrosis is expanding rapidly. Here’s a snapshot. […] Hyperhidrosis is a common side effect of antidepressants and can lead to treatment discontinuation. A recent meta-analysis suggests that the risk of hyperhidrosis differs by medication and is associated with the dopamine transporter. […] A recent study suggests that people with atopic dermatitis experience changes in sweat gland nervous activation and a higher frequency of hyperhidrosis, or excessive sweating. Other studies have shown different effects, though.

• #5 Hyperhidrosis prevalence and its impact on population – Hasimoto – Shanghai Chest

  https://shc.amegroups.org/article/view/5114/html

  Hyperhidrosis is a disorder characterized by excessive sweating which beyond the physiological need for body thermoregulation. The prevalence data available in the literature are practically nonexistent up to the beginning of the 21st century. The prevalence found in the articles varied from 0.072% to 16.3%. As to the impact on the quality of life, all articles have shown that such disorder affects in some way the life of the individuals. The data available in the literature regarding the prevalence of hyperhidrosis in the world population are practically nonexistent until the beginning of the 21st century, therefore up to some time ago little was known about the number of individuals bearing this disorder. The bibliographic review was done by using the PubMed database (until January 10th 2019). Sixteen articles that evaluated the prevalence of hyperhidrosis were found in the research, 15 of them were published from the 21st century. The prevalence of hyperhidrosis found in the articles ranged from 0.072% to 16.3%. The first citation found in the literature about the prevalence of hyperhidrosis is from 1977. The first published work with methodological description was the one by Strutton et al. in 2004. In 2007 China published two studies about the prevalence of hyperhidrosis. The lowest prevalence of published hyperhidrosis was 0.072%, by Chu et al. The highest prevalence published among all published papers was the one by Augustin et al. in 2013. The most recent work about the prevalence of hyperhidrosis belongs to our group, published in 2018. The existing data of hyperhidrosis prevalence in the world population are well varied and questionable due to the heterogeneity of methodologies used in several studies. The impacts of hyperhidrosis in the quality of life of the individuals are well known in daily practice and are confirmed by means of the applied questionnaires aimed at measuring the severity and the interference of the disorder in the daily life of its patient.

• #5 Primary Hyperhidrosis: Understanding Its Impact and Exploring Treatment Options

  https://www.rupahealth.com/post/primary-hyperhidrosis-understanding-its-impact-and-exploring-treatment-options

  Studies have shown that about 30% to 50% of individuals with primary hyperhidrosis have a family history of the condition, suggesting a hereditary predisposition. […] Primary hyperhidrosis is a chronic condition characterized by excessive and uncontrollable sweating, affecting specific areas of the body such as the hands, feet, underarms, and face. […] A variety of management options are available, including topical antiperspirants, oral medications, iontophoresis, Botox injections, and surgical options for severe cases. […] Early intervention and support can make a substantial difference in managing the challenges of living with primary hyperhidrosis.

• #6 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281

  In the past, there was little data on the prevalence of primary hyperhidrosis (Hh). Recently, however, more studies have been published in the medical literature – with illuminating statistics: […] Researchers reported the prevalence of hyperhidrosis in the United States as 4.8%, representing approximately 15.3 million people. That’s almost twice as many people as previously believed and this makes Hh more common than autism, melanoma, psoriasis, and peanut allergies. […] A study showed that, in Sweden, prevalence of primary hyperhidrosis was 5.5% with severe, primary hyperhidrosis affecting 1.4% of the population. Secondary hyperhidrosis was observed in 14.8% of the study participants. […] Research results found that the prevalence of primary hyperhidrosis among dermatology outpatients in Shanghai was 14.5% and in Vancouver was 12.3%.

• #6 Epidemiology of Primary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/epidemiology-of-primary-hyperhidrosis.html

  In the past, there was little data on the prevalence of primary hyperhidrosis (Hh). Recently, however, more studies have been published in the medical literature – with illuminating statistics: […] Researchers reported the prevalence of hyperhidrosis in the United States as 4.8%, representing approximately 15.3 million people. […] A study showed that, in Sweden, prevalence of primary hyperhidrosis was 5.5% with severe, primary hyperhidrosis affecting 1.4% of the population. […] Research results found that the prevalence of primary hyperhidrosis among dermatology outpatients in Shanghai was 14.5% and in Vancouver was 12.3%. […] Data showed that multifocal hyperhidrosis is common with 81% of patients reporting three or more hyperhidrotic sites. […] Data presented as an abstract on „pediatric breaking news” showed that 17.1% of teens surveyed experience excessive, uncontrollable sweating based on published diagnostic criteria.

• #6 Epidemiology of Hyperhidrosis in Danish Blood Donors | HTML | Acta Dermato-Venereologica

  https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3790

  Epidemiology of Hyperhidrosis in Danish Blood Donors […] The objectives of this retrospective cohort study were to estimate the prevalence of hyperhidrosis and to compare demographic, lifestyle, and socioeconomic parameters in blood donors with and without self-reported or hospital-diagnosed hyperhidrosis. Overall, 2,794 of 30,808 blood donors (9.07%; 95% confidence interval (95% CI) 8.759.40) had self-reported hyperhidrosis and 284 of 122,225 (0.23%; 95% CI 0.210.26) had hospital-diagnosed hyperhidrosis. Self-reported hyperhidrosis was associated with smoking (odds ratio (OR) 1.17; 95% CI 1.051.31), overweight (OR 1.72; 95% CI 1.581.87), unemployed (OR 1.60; 95% CI 1.242.08), short education (OR 0.76; 95% CI 0.640.90), and lower income (beta-coefficient 26,121; 95% CI 37,931, 14,311). Hospital-diagnosed hyperhidrosis did not differ from controls. Thus, self-reported hyperhidrosis was associated with potential hyperhidrosis risk factors (smoking, overweight) and disease implications (unemployment, low education level and income).

• #6 Epidemiology of Primary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/epidemiology-of-primary-hyperhidrosis.html

  Results showed that the prevalence of hyperhidrosis in the U.S. was 2.8% (7.8 million Americans). […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating. […] A series of studies on patients treated by endoscopic thoracic sympathectomy (ETS) reported a family history in 35% and 56% of participants. […] A study of the familial aggregation of hyperhidrosis also suggested that the disorder may be more common than previously thought. […] Focal primary hyperhidrosis has an onset during childhood or adolescence. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] In 2016, results from 1,985 survey participants showed that axillary hyperhidrosis was the most prevalent type of hyperhidrosis in the study sample (68%) followed by palmar (65%) and plantar (64%). […] It should be noted here, again, the primary focal Hh is most typically a multifocal disease. […] Key take-aways: primary Hh is relatively common, multifocal, and chronic with an onset in youth and an apparent genetic link — yet, diagnosis and treatment is often delayed for years.

• #6 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281

  A series of studies on patients treated by endoscopic thoracic sympathectomy (ETS) reported a family history in 35% and 56% of participants. […] A study of the familial aggregation of hyperhidrosis also suggested that the disorder may be more common than previously thought. […] Focal primary hyperhidrosis usually has an onset during childhood or adolescence. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] Key take-aways: primary Hh is relatively common, multifocal, and chronic with an onset in youth and an apparent genetic link — yet, diagnosis and treatment is often delayed for years.

• #6 Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis

  Our understanding of the international prevalence, clinical characteristics, and patient burden of primary hyperhidrosis is expanding rapidly. Here’s a snapshot. […] Hyperhidrosis is a common side effect of antidepressants and can lead to treatment discontinuation. A recent meta-analysis suggests that the risk of hyperhidrosis differs by medication and is associated with the dopamine transporter. […] A recent study suggests that people with atopic dermatitis experience changes in sweat gland nervous activation and a higher frequency of hyperhidrosis, or excessive sweating. Other studies have shown different effects, though.

• #7 Hyperhidrosis Limits Patients’ Daily Functioning, Quality of Life Across Several Different Regions

  https://www.consultantlive.com/view/hyperhidrosis-limits-patients-daily-functioning-quality-of-life-across-several-different-regions

  The incidence of hyperhidrosis was found to have exhibited variations from 0.13% in the UK to 0.28% in the USA, with a higher occurrence being seen among females. […] Likewise, the investigators reported that hyperhidrosis prevalence ranged from 2.8% 4.8% for the US population to 18.40% for Chinese inpatients, whereas the axillary hyperhidrosis prevalence fluctuated from 1.4% for the US population to 5.75% for Japanese employees and/or students. […] While limited evidence exists on the hyperhidrosis burden, particularly among those in Japan, it still was shown to be a substantial hindrance to patients’ overall daily functioning. […] Despite limited data, available evidence suggests that hyperhidrosis places physical, psychological, and economic burdens on the daily lives of individual patients, they wrote. The introduction of new treatments is expected to improve the medical environment of hyperhidrosis and reduce the burden on patients.

• #7

  https://www.termedia.pl/Hyperhidrosis-disease-aetiology-classification-and-r-nmanagement-in-the-light-of-modern-treatment-modalities,7,46948,1,1.html

  Every hyperhidrosis manifestation in older patients, i.e. above 60 years old, should urge physicians to seek for secondary causes of the disease. […] Additionally, a correlation between the location of sweat overproduction and patients age was observed. Adolescents and young adults demonstrated the hyperhidrosis symptoms more often on palms, whereas adults around axillary areas.

• #7 Hyperhidrosis – Wikipedia

  https://en.wikipedia.org/wiki/Hyperhidrosis

  It is estimated that the incidence of focal hyperhidrosis may be as high as 2.8% of the population of the United States. […] It affects men and women equally, and most commonly occurs among people aged 25-64 years, though some may have been affected since early childhood. […] About 30-50% of people have another family member affected, implying a genetic predisposition. […] In 2006, researchers at Saga University in Japan reported that primary palmar hyperhidrosis maps to gene locus 14q11.2-q13.

• #7 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis

  https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281

  A series of studies on patients treated by endoscopic thoracic sympathectomy (ETS) reported a family history in 35% and 56% of participants. […] A study of the familial aggregation of hyperhidrosis also suggested that the disorder may be more common than previously thought. […] Focal primary hyperhidrosis usually has an onset during childhood or adolescence. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] Key take-aways: primary Hh is relatively common, multifocal, and chronic with an onset in youth and an apparent genetic link — yet, diagnosis and treatment is often delayed for years.

• #7 Excessive Sweating (Hyperhidrosis) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/excessive-sweating

  Excessive sweating that can get in the way of daily life and cause skin infections. […] The condition affects about 3% of Americans. […] Hyperhidrosis tends to run in families. […] More people probably have hyperhidrosis than are diagnosed.

• #8 SciELO Brasil – Hyperhidrosis: prevalence and impact on quality of life Hyperhidrosis: prevalence and impact on quality of life

  https://www.scielo.br/j/jbpneu/a/gxS3VxQSW3j7hX5MkLXDxqz/

  Objective: To determine the prevalence of primary hyperhidrosis in the city of Botucatu, Brazil, and to evaluate how this disorder affects the quality of life in those suffering from it. […] A total of 4,133 residents, in 1,351 households, were surveyed. Excessive sweating was reported by 85 residents (prevalence = 2.07%), of whom 51 (60%) were female. […] Although the prevalence of self-reported excessive sweating was greater than 2%, the actual prevalence of primary hyperhidrosis in our sample was 0.93% and nearly 50% of the respondents with primary hyperhidrosis reported impaired quality of life. […] There are few data on the worldwide prevalence of hyperhidrosis, reported values ranging from 0.072% to 9%. […] In our study, the prevalence of hyperhidrosis after the application of a questionnaire by trained interviewers was above 2%, as observed by Strutton et al. However, after medical evaluation, 25% of the patients that reported excessive sweating actually showed normal sweating and 30% had SH. Consequently, more than half of the subjects that reported excessive sweating did not actually have PH. Therefore, after medical evaluation, the estimated prevalence of PH decreased to less than 1%.

• #8 Primary Hyperhidrosis: Understanding Its Impact and Exploring Treatment Options

  https://www.rupahealth.com/post/primary-hyperhidrosis-understanding-its-impact-and-exploring-treatment-options

  Studies have shown that about 30% to 50% of individuals with primary hyperhidrosis have a family history of the condition, suggesting a hereditary predisposition. […] Primary hyperhidrosis is a chronic condition characterized by excessive and uncontrollable sweating, affecting specific areas of the body such as the hands, feet, underarms, and face. […] A variety of management options are available, including topical antiperspirants, oral medications, iontophoresis, Botox injections, and surgical options for severe cases. […] Early intervention and support can make a substantial difference in managing the challenges of living with primary hyperhidrosis.

• #9 Epidemiology of Hyperhidrosis in Danish Blood Donors | HTML | Acta Dermato-Venereologica

  https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3790

  Hyperhidrosis (HH) is defined as pathologically increased sweat production that affects quality of life, which leaves a broad scope for interpretation. Thus, the prevalence of self-reported HH is 221% and the prevalence of hospital-diagnosed HH is 14%. The objectives of this study were therefore to estimate the prevalence of HH and to compare demographic, lifestyle, and socioeconomic parameters in individuals with and without self-reported or hospital-diagnosed HH. […] Overall, 2,794 of 30,808 blood donors had moderate-to-severe self-reported HH, which implied a prevalence of 9.07% (95% confidence interval (95% CI) 8.759.40). In contrast, 284 of 122,225 blood donors had hospital-diagnosed HH, which equated to a prevalence of 0.23% (95% CI 0.210.26). Self-reported HH was associated with overweight, smoking, reduced income, unemployed vs working and lower probability of short education vs high school. Hospital-diagnosed HH was not associated with any of the analysed parameters.

• #10 Hyperhidrosis prevalence and its impact on population – Hasimoto – Shanghai Chest

  https://shc.amegroups.org/article/view/5114/html

  Hyperhidrosis is a disorder characterized by excessive sweating which beyond the physiological need for body thermoregulation. The prevalence data available in the literature are practically nonexistent up to the beginning of the 21st century. The prevalence found in the articles varied from 0.072% to 16.3%. As to the impact on the quality of life, all articles have shown that such disorder affects in some way the life of the individuals. The data available in the literature regarding the prevalence of hyperhidrosis in the world population are practically nonexistent until the beginning of the 21st century, therefore up to some time ago little was known about the number of individuals bearing this disorder. The bibliographic review was done by using the PubMed database (until January 10th 2019). Sixteen articles that evaluated the prevalence of hyperhidrosis were found in the research, 15 of them were published from the 21st century. The prevalence of hyperhidrosis found in the articles ranged from 0.072% to 16.3%. The first citation found in the literature about the prevalence of hyperhidrosis is from 1977. The first published work with methodological description was the one by Strutton et al. in 2004. In 2007 China published two studies about the prevalence of hyperhidrosis. The lowest prevalence of published hyperhidrosis was 0.072%, by Chu et al. The highest prevalence published among all published papers was the one by Augustin et al. in 2013. The most recent work about the prevalence of hyperhidrosis belongs to our group, published in 2018. The existing data of hyperhidrosis prevalence in the world population are well varied and questionable due to the heterogeneity of methodologies used in several studies. The impacts of hyperhidrosis in the quality of life of the individuals are well known in daily practice and are confirmed by means of the applied questionnaires aimed at measuring the severity and the interference of the disorder in the daily life of its patient.

• #11 SciELO Brasil – Hyperhidrosis: prevalence and impact on quality of life Hyperhidrosis: prevalence and impact on quality of life

  https://www.scielo.br/j/jbpneu/a/gxS3VxQSW3j7hX5MkLXDxqz/

  Objective: To determine the prevalence of primary hyperhidrosis in the city of Botucatu, Brazil, and to evaluate how this disorder affects the quality of life in those suffering from it. […] A total of 4,133 residents, in 1,351 households, were surveyed. Excessive sweating was reported by 85 residents (prevalence = 2.07%), of whom 51 (60%) were female. […] Although the prevalence of self-reported excessive sweating was greater than 2%, the actual prevalence of primary hyperhidrosis in our sample was 0.93% and nearly 50% of the respondents with primary hyperhidrosis reported impaired quality of life. […] There are few data on the worldwide prevalence of hyperhidrosis, reported values ranging from 0.072% to 9%. […] In our study, the prevalence of hyperhidrosis after the application of a questionnaire by trained interviewers was above 2%, as observed by Strutton et al. However, after medical evaluation, 25% of the patients that reported excessive sweating actually showed normal sweating and 30% had SH. Consequently, more than half of the subjects that reported excessive sweating did not actually have PH. Therefore, after medical evaluation, the estimated prevalence of PH decreased to less than 1%.

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