Materiały źródłowe

• #1 Hyperhidrosis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hyperhidrosis/symptoms-causes/syc-20367152

  Hyperhidrosis (hi-pur-hi-DROE-sis) is excessive sweating that’s not always related to heat or exercise. […] Primary hyperhidrosis is caused by faulty nerve signals that trigger eccrine sweat glands to become overactive. It usually affects the palms, soles, underarms and sometimes the face. […] There is no medical cause for this type of hyperhidrosis. It can run in families. […] Secondary hyperhidrosis is caused by an underlying medical condition or by taking certain medications, such as pain relievers, antidepressants, and some diabetes and hormonal medications. This type of hyperhidrosis may cause sweating all over the body. Conditions that might cause it include: Diabetes, Menopause hot flashes, Thyroid problems, Some types of cancer, Nervous system disorders, Infections.

• #1 Hyperhidrosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459227/

  Hyperhidrosis can be categorized as either primary or secondary. This distinction is important because treatment and management may significantly differ between the two groups. The etiology of primary hyperhidrosis remains unknown despite multiple literature reviews. Genetic factors are believed to play a role in excessive neural stimulation, although this is poorly understood. Secondary causes are usually easier to identify because they are associated with medications such as dopamine agonists, selective serotonin reuptake inhibitors (SSRIs), antipsychotics, and insulin; systemic disorders such as diabetes mellitus, hyperthyroidism, Parkinson disease, and other neurologic disorders; and tumors such as pheochromocytoma and lymphoma. […] Almost any febrile illness can cause hyperhidrosis. Chronic excessive alcohol consumption and tuberculosis are also associated with hyperhidrosis. Developing segmental or localized hyperhidrosis is rare. The condition can present on some adults’ forehead, axilla, palm, feet, or forearm. Some postmenopausal women develop moderate to severe hyperhidrosis around their face and scalp. Unilateral hyperhidrosis tends to be more common on the right side of the face or arm, with anhidrosis on the left side.

• #1 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Hyperhidrosis is excessive sweating that affects patients’ quality of life, resulting in social and work impairment and emotional distress. Primary hyperhidrosis is bilaterally symmetric, focal, excessive sweating of the axillae, palms, soles, or craniofacial region not caused by other underlying conditions. Secondary hyperhidrosis may be focal or generalized, and is caused by an underlying medical condition or medication use. […] The cause of primary hyperhidrosis is not well understood. Eccrine sweat glands distributed throughout the body, but heavily concentrated on the palms, soles, axillae, and face are innervated by postganglionic autonomic nerve fibers and stimulated by the neurotransmitter acetylcholine. It is thought that increased or aberrant sympathetic stimulation of the eccrine sweat glands is responsible for the increased sweating rather than an increased number or size of the glands. […] Persons with primary hyperhidrosis have a higher-than-normal basal level of sweat production and an increased response to normal stimuli, such as emotional or physical stress.

• #1 Hyperhidrosis | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/skin-hair-and-nails/hyperhidrosis/

  Some cases of primary hyperhidrosis appear to run in families, which suggests a genetic mutation may be the cause. […] If a cause of hyperhidrosis can be identified, its known as secondary hyperhidrosis. […] Secondary hyperhidrosis can have a number of different triggers, including: pregnancy, the menopause when a womans monthly periods stop, anxiety, low blood sugar (hypoglycaemia), an overactive thyroid gland (hyperthyroidism), obesity, certain medications including some antidepressants, propranolol, pilocarpine, and bethanechol, being drunk or high on drugs, or withdrawing from alcohol or drugs if you have become addicted to them, some infections, such as tuberculosis and HIV, Parkinsons disease, disorders of the blood cells or bone marrow, such as Hodgkin lymphoma.

• #1 Hyperhidrosis: Symptoms, Causes, Treatment

  https://www.health.com/condition/hyperhidrosis-overview

  Hyperhidrosis is the medical term for excessive sweating. The condition can begin in childhood, adolescence, or as an adult. For many people, excessive sweating runs in the family, and problems with sweat are an everyday, normal occurrence. […] Others may notice excess sweat began after taking medication or being diagnosed with a disease like diabetes. However, because hyperhidrosis can affect people physically and psychologically and drastically affect one’s confidence, treatment can improve your quality of life. […] There are two types of hyperhidrosis, primary and secondary, which are diagnosed based on the cause of excessive sweating. […] This type of hyperhidrosis typically begins in childhood or around puberty. Excessive sweating also runs in families; one study found family history in 30 to 50% of primary hyperhidrosis cases.

• #1 Excessive sweating

  https://www.mayoclinic.org/symptoms/excessive-sweating/basics/causes/sym-20050780

  If excessive sweating has no underlying medical cause, it’s called primary hyperhidrosis. It happens when excess sweating is not triggered by a rise in temperature or physical activity. Primary hyperhidrosis may be at least partly hereditary. […] If the excess sweating is due to an underlying medical condition, it’s called secondary hyperhidrosis. […] Health conditions that might cause excessive sweating include: Acromegaly, Diabetic hypoglycemia, Fever of undetermined cause, Hyperthyroidism (overactive thyroid) also known as overactive thyroid, Infection, Leukemia, Lymphoma, Malaria, Medication side effects, such as sometimes experienced when taking some beta blockers and antidepressants, Menopause, Neurologic disease, Pheochromocytoma (a rare adrenal gland tumor), Tuberculosis. […] Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.

• #1 Excessive Sweating (Hyperhidrosis): Causes and Treatments – K Health

  https://khealth.com/learn/symptom/excessive-sweating/

  Excessive sweating (or hyperhidrosis) usually results from an over activation of the sympathetic nervous system (SNS). […] When a person has hyperhidrosis, the sympathetic nervous system releases excessive amounts of acetylcholine which activates sweat glands. […] Secondary hyperhidrosis usually affects the whole body and typically presents due to adverse effects of certain metabolic disorders, anxiety, cancer, infection, some medications, and foods. […] Some of the metabolic disorders that can cause hyperhidrosis include: Hyperthyroidism (overactive thyroid), Hyperpituitarism (pituitary disease), Hyperglycemia (high blood sugar), Hypoglycemia (low blood sugar), Pheochromocytoma (benign tumor in the adrenal glands), Gout (inflammatory arthritis due to a crystal called uric acid). […] Menopause can cause increased sweating, especially on the face, as well as generalized hot flashes.

• #1 Hyperhidrosis – Wikipedia

  https://en.wikipedia.org/wiki/Hyperhidrosis

  Certain endocrine conditions are also known to cause secondary hyperhidrosis including diabetes mellitus (especially when blood sugars are low), acromegaly, hyperpituitarism, pheochromocytoma (tumor of the adrenal glands, present in 71% of patients) and various forms of thyroid disease. […] Use of selective serotonin reuptake inhibitors (e.g., sertraline) is a common cause of medication-induced secondary hyperhidrosis. Other medications associated with secondary hyperhidrosis include tricyclic antidepressants, stimulants, opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), glyburide, insulin, anxiolytic agents, adrenergic agonists, and cholinergic agonists. […] In people with a history of spinal cord injuries, autonomic dysreflexia, orthostatic hypotension, and posttraumatic syringomyelia can be associated with hyperhidrosis.

• #1 Hyperhidrosis: Causes

  https://www.aad.org/public/diseases/a-z/hyperhidrosis-causes

  Parkinsons can affect the part of the nervous system that controls sweating. Excessive sweating can worsen as Parkinsons progresses. […] Unlike primary hyperhidrosis, secondary hyperhidrosis can cause you to sweat while youre asleep. […] You may develop secondary hyperhidrosis if you have one of the following: Take medication (described above) that can cause excessive sweating or Have a medical condition (described above) that can lead to excessive sweating. […] The etiology, diagnosis, and management of hyperhidrosis: A comprehensive review: Etiology and clinical work-up.

• #1 Hyperhidrosis: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/007259.htm

  Hyperhidrosis is a medical condition in which a person sweats excessively and unpredictably. […] Excessive sweating occurs without such triggers. People with hyperhidrosis appear to have overactive sweat glands. […] When excessive sweating affects the hands, feet, and armpits, it is called focal hyperhidrosis. In most cases, no cause can be found. It seems to run in families. […] Sweating that is not caused by another disease is called primary hyperhidrosis. […] If the sweating occurs as a result of another medical condition, it is called secondary hyperhidrosis. […] Conditions that cause secondary hyperhidrosis include: Acromegaly, Anxiety conditions, Cancer, Carcinoid syndrome, Certain medicines and substances of abuse, Glucose control disorders (diabetes and hypoglycemia), Heart disease, such as heart attack, Overactive thyroid, Lung disease, Menopause, Parkinson disease, Pheochromocytoma (adrenal gland tumor), Spinal cord injury, Stroke, Tuberculosis or other infections.

• #1 Hyperhidrosis – Dermatologic Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/dermatologic-disorders/sweating-disorders/hyperhidrosis

  Hyperhidrosis can be focal or generalized. […] Emotional causes are common, causing sweating on the palms, soles, axillae, and forehead at times of anxiety, excitement, anger, or fear. […] Pathologic causes include diabetic neuropathy, facial herpes zoster, cervical sympathetic ganglion invasion, central nervous system injury or disease, or parotid gland injury. […] Frey syndrome is a neurologic condition due to injury to or around the parotid glands resulting from surgery, infection, or trauma. […] Other causes of focal sweating include pretibial myxedema (shins), hypertrophic osteoarthropathy (palms), blue rubber bleb nevus syndrome, and glomus tumor (over lesions). […] Generalized sweating involves most of the body. Although most cases are idiopathic, numerous conditions can be involved.

• #1 Hyperhidrosis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/1073359-overview

  Hyperhidrosis may be idiopathic or secondary to other diseases, metabolic disorders, febrile illnesses, or medication use. […] Generalized hyperhidrosis may be secondary to numerous conditions including the following: Neurologic or neoplastic diseases: Contralateral hyperhidrosis in the left ophthalmic trigeminal division was documented on the forehead after a lateral medullary infarction. […] Paroxysmal sympathetic hyperactivity after a spontaneous intracerebral hemorrhage may also produce hyperhidrosis. […] Spontaneous periodic hypothermia and hyperhidrosis: This is postulated to be a rare cerebral neurotransmitter disorder. […] Metabolic disorders or processes (eg, thyrotoxicosis, diabetes mellitus, hypoglycemia, gout, pheochromocytoma, menopause) […] Febrile illnesses […] Medications: Use of medications may affect one or more components of human thermoregulation and induce hyperhidrosis.

• #1 Focal Secondary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/causes-of-secondary-hyperhidrosis/focal-hyperhidrosis.html

  A variety of diseases can cause localized hyperhidrosis. Neurologic injury and dermatologic syndromes make up the majority of secondary causes of excessive focal sweat production. Acute spinal cord injury would be expected to lead to loss of sweating below the site of injury, but such injuries can also lead to localized areas of hyperhidrosis seen months to years after the injury. […] Central nervous system injuries such as strokes leading to hemispheric or medullary infarcts can lead to hyperhidrosis on the ipsilateral and contralateral side, respectively. […] An intrathoracic tumor impinging on the sympathetic trunk or postganglionic nerves can cause hyperhidrosis by a similar mechanism. […] In reflex sympathetic dystrophy, hyperhidrosis is often seen in the affected area. […] Compensatory hyperhidrosis is also seen in diabetic neuropathy, after thoracic sympathectomy (ETS), and in Ross syndrome, a rare syndrome in which anhidrosis occurs in a dermatomal pattern due to focal dysfunction of the sympathetic fibers innervating sweat glands.

• #1 Hyperhidrosis – Wikipedia

  https://en.wikipedia.org/wiki/Hyperhidrosis

  Hyperhidrosis is a medical condition in which a person exhibits excessive sweating, more than is required for the regulation of body temperature. […] The cause of primary hyperhidrosis is unknown. Anxiety or excitement can exacerbate the condition. A common complaint of people is a nervous condition associated with sweating, then sweat more because the person is nervous. Other factors can play a role, including certain foods and drinks, nicotine, caffeine, and smells. […] Similarly, secondary (generalized) hyperhidrosis has many causes including certain types of cancer, disturbances of the endocrine system, infections, and medications. […] Primary (focal) hyperhidrosis has many causes. […] A variety of cancers have been associated with the development of secondary hyperhidrosis including lymphoma, pheochromocytoma, carcinoid tumors (resulting in carcinoid syndrome), and tumors within the thoracic cavity.

• #1 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Hyperhidrosis-Causes.aspx

  When the cause of the condition is clear, the condition is called secondary hyperhidrosis. The onset of secondary hyperhidrosis is often more sudden than the onset of primary hyperhidrosis and is likely to cause sweating across the whole body. This can be triggered by many underlying factors, including the following: menopause, pregnancy, anxiety, low blood sugar or hypoglycemia, hyperthyroidism, diabetes, obesity, some medications such as anti-depressants and the beta-blockers, certain infections, including HIV and tuberculosis, Parkinson’s disease, disorders of the blood cell or bone marrow including Hodgkin lymphoma.

• #1 Hyperhidrosis: Causes

  https://www.aad.org/public/diseases/a-z/hyperhidrosis-causes

  Hyperhidrosis is a treatable medical condition that makes people sweat excessively. They sweat more than is needed to cool their body. […] The cause depends on the type of hyperhidrosis you have. There are two types of hyperhidrosis: Primary hyperhidrosis and Secondary hyperhidrosis. […] Its believed that this type of excessive sweating is caused by faulty signals coming from certain nerves, which tell the body when to sweat. Its possible that these nerves over-react, which leads to excessive sweating. […] If youve been diagnosed with secondary hyperhidrosis, the excessive sweating is usually due to one of the following: A medication youre taking or Another medical condition you have. […] Medical conditions that can cause hyperhidrosis include diabetes, Parkinsons disease, and rheumatoid arthritis. Heart failure and stroke can also cause secondary hyperhidrosis, as can menopause.

• #1 Diaphoresis: Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/24496-diaphoresis

  When your thyroid becomes overactive, it makes too much of a hormone called thyroxine. This is called hyperthyroidism. […] If you have diabetes, excessive sweating may be a sign of low blood sugar (hypoglycemia). […] Excessive sweating is one of the most common signs of a heart attack (myocardial infarction). […] Diaphoresis is a common symptom of substance withdrawal. […] Certain cancers and cancer treatments can cause excessive sweating. […] Severe allergic reactions to triggers such as peanuts, shellfish or bee stings can cause anaphylaxis. […] Certain prescription and over-the-counter (OTC) medications can cause side effects that include excessive sweating.

• #1 Primary and Secondary Hyperhidrosis: Causes

  https://www.verywellhealth.com/hyperhidrosis-causes-4777757

  A common cause of secondary hyperhidrosis is extra body weight and obesity. This is likely due to body heat becoming trapped by adipose tissue, kicking off the body’s natural cooling response, and causing excessive perspiration. […] Several factors related to normal cardiovascular function overlap with hyperhidrosis. The same mechanism that triggers sweating in hyperhidrosis causes an increase in heart rate and blood pressure. […] The sympathetic nervous system, which activates the fight-or-flight response, plays a role in hyperhidrosis. The fight-or-flight response causes an increase in heart rate and blood pressure, which leads to excessive sweating. […] In primary focal hyperhidrosis, sweating usually starts during childhood, which suggests it may be genetic. […] A key difference between the two types is the location of excess sweating. Primary hyperhidrosis typically affects the soles of the feet, the palms of the hands, the underarms (axillary hyperhidrosis), or the face and scalp. People with secondary hyperhidrosis sweat all over.

• #1 Generalized Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/causes-of-secondary-hyperhidrosis/generalized-hyperhidrosis.html

  Generalized hyperhidrosis is usually secondary to an underlying medical condition or can have a physiological basis with heat, humidity, or exercise, leading to excessive sweating out of proportion to thermoregulatory needs. […] Infections, neoplasia, metabolic and endocrine disorders, high catecholamine states, drug therapy, and neurologic problems can all be associated with systemic hyperhidrosis. […] Endocrine disorders associated with hyperhidrosis include thyrotoxicosis, hyperpituitarism, diabetes mellitus, pheochromocytoma, hypoglycemia, gout, and menopause. […] Excessive sweating, tachycardia, and headache in a patient with hyperhidrosis should raise suspicion of pheochromocytoma and prompt measurement of catecholamine levels. […] Acute and chronic infections and neoplasia can lead to fever followed by excessive sweating.

• #1 Hyperhidrosis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/1073359-overview

  Chronic alcoholism […] Hodgkin disease or tuberculosis (in nocturnal hyperhidrosis) […] Localized unilateral or segmental hyperhidrosis is rare and of unknown origin. […] Primary focal hyperhidrosis tends to arise on the palms, plantar feet, and axillae, as well as from the face and scalp of children and young adults; there seems to have a distinct subtype of craniofacial hyperhidrosis in postmenopausal women. […] Unilateral hyperhidrosis with accompanying contralateral anhidrosis is also rare. […] Localized hyperhidrosis may also be associated with the following: Gustatory stimuli (associated with Frey syndrome, encephalitis, syringomyelia, diabetic neuropathies, herpes zoster parotitis, and parotid abscess) […] Eccrine nevus: This may be associated with severe localized hyperhidrosis. […] Eccrine angiomatous hamartoma: This is a rare, benign malformation characterized by both eccrine and vascular components. […] Spinal cord tumors: Rarely, hyperhidrosis may be an initial symptom.

• #1 Reddit – The heart of the internet

  https://www.reddit.com/r/Hyperhidrosis/comments/1gk2d71/what_causes_hyperhidrosis/

  Hyperhidrosis, or excessive sweating, can be caused by several factors, and its often classified into two main types based on the cause: […] The exact cause isnt fully understood, but its believed to be related to overactivity of the sympathetic nervous system, which controls sweat glands. […] This form of hyperhidrosis often runs in families, suggesting a genetic component. […] This type of hyperhidrosis is caused by an underlying medical condition or a side effect of medication. […] Common medical conditions that can cause secondary hyperhidrosis include: […] Endocrine disorders: Hyperthyroidism, diabetes, and menopause (hot flashes) can increase sweating. […] Infections: Tuberculosis and HIV are examples of infections that may cause excessive sweating, especially night sweats.

• #1 Drug-induced hyperhidrosis

  https://dermnetnz.org/topics/drug-induced-hyperhidrosis

  Hyperhidrosis is excessive sweating due to the overstimulation of the eccrine sweat glands by a neurotransmitter, acetylcholine. Hyperhidrosis can be primary, which happens early in life, or secondary, which is caused by systemic or neurological diseases, or as a side effect of medications. […] Drug-induced hyperhidrosis is the most common cause of secondary hyperhidrosis. Drugs can act on the hypothalamus or at spinal thermoregulatory centres, at sympathetic ganglia or at the eccrine-neuroeffector junction. It results from the release of acetylcholine by medications that block the action of acetylcholinesterase, an enzyme that breaks down the neurotransmitter. […] Other factors that can contribute to increased sweating include a family history of increased sweating, and underlying medical conditions such as obesity, diabetes, hyperthyroidism, menopause, or cancer.

• #1 Drug-induced hyperhidrosis

  https://dermnetnz.org/topics/drug-induced-hyperhidrosis

  Different classes of medications can influence the sweating response by acting centrally in the brain and the peripheral nervous system. […] Medications used to treat psychiatric conditions that can cause hyperhidrosis include: Selective serotonin reuptake inhibitors (SSRIs), such as citalopram; Tricyclic antidepressants, such as amitriptyline; Antipsychotics, such as haloperidol and clozapine. […] Medications that can affect endocrine function and thus cause hyperhidrosis can include: Systemic corticosteroids; Thyroid medications; Diabetic medications such as glipizide and insulin. […] Withdrawal from non-prescription drugs such as alcohol and caffeine can also cause generalised hyperhidrosis. […] Drug-induced hyperhidrosis is diagnosed clinically. Other causes of secondary hyperhidrosis should be excluded, such as an underlying infection, malignancy, neurological, or endocrine conditions.

• #1 Hyperhidrosis: Types, Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/17113-hyperhidrosis

  Hyperhidrosis is excessive sweating. This condition happens when you sweat more than what your body needs to regulate your temperature. Hyperhidrosis is the result of your sweat glands overworking. Primary focal hyperhidrosis is a chronic skin condition. A genetic change (mutation) causes this condition. You can inherit it from your biological family. Secondary generalized hyperhidrosis is excessive sweating caused by an underlying medical condition or its a side effect of a medication. Overactive sweat glands cause hyperhidrosis. Research is ongoing to learn more about why your glands make too much sweat. Hyperhidrosis (generalized) could be a sign of an underlying medical condition including but not limited to: Acromegaly, An infection (tuberculosis), Anxiety, Cancer, Diabetes, Heart disease or heart failure, Hyperthyroidism, Menopause, Obesity, Parkinsons disease. Yes, you may be more at risk of hyperhidrosis, specifically focal hyperhidrosis, if someone in your biological family has the condition. Research indicates that a hereditary genetic mutation or change to your DNA could cause hyperhidrosis. […] Certain medications can cause sweating as a side effect, including but not limited to: Albuterol (Proventil), Bupropion (Wellbutrin), Hydrocodone, Insulin (Humulin R, Novolin R), Levothyroxine, Lisinopril, Naproxen (Aleve), Omeprazole (Prilosec), Sertraline (Zoloft).

• #1 Generalized Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/causes-of-secondary-hyperhidrosis/generalized-hyperhidrosis.html

  Conditions associated with high sympathetic discharge can lead to excessive sweating. […] Drugs reported to cause hyperhidrosis include propanolol, physostigmine, pilocarpine, tricyclic antidepressants, fluoxetine, venlafaxine, and cyclobenzaprine, but there are more, as well. […] Familial dysautonomia, or Riley-Day syndrome, can lead to generalized hyperhidrosis. […] Hyperhidrosis has been seen without hyperthermia in patients with a hypothalamic stroke.

• #1 Focal Secondary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/causes-of-secondary-hyperhidrosis/focal-hyperhidrosis.html

  It should be noted that compensatory sweating after ETS for the treatment of hyperhidrosis has been reported as potentially being as severe or more severe than the original sweating problem and may require treatment in itself. […] Conditions sometimes associated with palmoplantar hyperhidrosis include Raynauds disease, erthromelalgia, atrioventricular fistula, cold injury, rheumatoid arthritis, and some rare dermatologic syndromes. […] After inflammation or surgery near the parotid gland, cross-talk between regenerating nerves that cause salivation and sympathetic nerves causes excessive facial sweating.

• #1 Hyperhidrosis Explained: Why Some Sweat More | Parfaire

  https://www.parfaire.com/blog/hyperhidrosis-explained-why-some-people-sweat-more-than-others/

  While sweating is a natural function regulated by sweat glands, some individuals experience persistent and uncontrollable sweating unrelated to external factors like heat or exercise. This condition, known as hyperhidrosis, occurs when the eccrine glands become overactive, producing more sweat than necessary. […] Several factors can trigger excessive sweating, including: Heat and humidity, Stress and anxiety, Physical activity, Spicy foods, Caffeine, Certain medications. […] For many people with hyperhidrosis, the condition runs in the family. Primary hyperhidrosis is often hereditary, meaning individuals with close relatives who experience excessive sweating are more likely to develop it themselves. This hyperhidrosis is typically caused by overactive nerves that stimulate the eccrine glands, leading to excessive perspiration even in normal conditions.

• #1 Excessive Sweating (Hyperhidrosis) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/excessive-sweating

  Excessive sweating that can get in the way of daily life and cause skin infections. […] In people with hyperhidrosis, the body’s 2 to 4 million sweat glands are overactive, causing profuse perspiration at times when others would sweat lightly (if at all). […] Sometimes, however, hyperhidrosis can be caused by disorders of the thyroid, menopause, or certain medications. […] This type of hyperhidrosis can happen in one or two locations on the body, or it can affect the entire body. It results from some medications or from a medical condition. […] Hyperhidrosis tends to run in families. […] Some medical conditions (like menopause) may cause sweating. […] Certain medications can cause excessive sweating.

• #1 Hyperhidrosis: Causes, Symptoms, and Treatment | RoRoRo

  https://ro.co/hyperhidrosis/hyperhidrosis-causes-symptoms-and-treatment/

  Hyperhidrosis is a medical condition characterized by excessive sweating. […] In hyperhidrosis, you sweat more than usual and often without the typical triggers. One theory to explain hyperhidrosis is that there may be an abnormally increased release of acetylcholine, or that the nerve signals cannot be turned off appropriately. […] There are two types of hyperhidrosis: primary focal hyperhidrosis and secondary generalized hyperhidrosis. […] Primary hyperhidrosis is not caused by another medical condition or medications that you may be taking; excessive sweating is the medical condition. […] Secondary hyperhidrosis differs because it is excessive sweating that is caused by a medical condition, such as hyperthyroidism, diabetes, or menopause; it can also be due to medication side effects.

• #1 Hyperhidrosis – Wikipedia

  https://en.wikipedia.org/wiki/Hyperhidrosis

  Hyperhidrosis can also have devastating emotional effects on one’s individual life. […] Those with hyperhidrosis may have greater stress levels and more frequent depression. […] Excessive sweating or focal hyperhidrosis of the hands interferes with many routine activities, such as securely grasping objects.

• #1 Excessive Sweating | Hyperhidrosis Symptoms | Spire Healthcare

  https://www.spirehealthcare.com/symptoms/excessive-sweating/

  Excessive sweating refers to sweating when your body does not need to cool down. […] Sometimes, frequent and excessive sweating all over your body can be a symptom of: […] Less commonly it can be caused by: […] Primary (idiopathic) focal hyperhidrosis […] It is not associated with any other conditions and the cause is unknown. […] Secondary focal hyperhidrosis […] There is usually a known cause eg spinal disease or injury causing excessive sweating in one leg. […] Generalised hyperhidrosis […] It usually has a known cause, such as anxiety or side effects caused by certain medications. […] Excessive sweating is not a serious health condition but can make you feel embarrassed and anxious, especially in social situations or when doing sports. […] If you have excessive sweating after eating or drinking, you may be prescribed propantheline tablets. […] Botulinum toxin stops the nerves that control your sweat glands from working. […] Excessive sweating can be a symptom of a complication that occurs as a result of poorly controlled diabetes called autonomic neuropathy.

• #1 Excessive Sweating (Hyperhidrosis)

  https://www.massgeneral.org/condition/excessive-sweating

  Excessive sweating is when the body releases too much fluid from the sweat glands. Its also called hyperhidrosis. Its often an ongoing (chronic) condition. […] In most cases, the cause isnt known. This is known as primary hyperhidrosis. But it may be caused by thyroid problems, low blood sugar, nervous system disorders, medicines, or other problems. This is known as secondary hyperhidrosis. In some cases, the cause of hyperhidrosis can be serious. […] Excessive sweating can affect the entire body, but it usually occurs in the palms, soles, armpits, or groin area. […] It may be caused by thyroid problems, low blood sugar, nervous system disorders, medicines, or other problems. […] The condition can affect a person’s quality of life and cause social isolation and depression. […] Treatment may include antiperspirant, medicine, injections, surgery, or treatments for another health condition.

• #1 The etiology, diagnosis, and management of hyperhidrosis: A comprehensive review: Etiology and clinical work-up – PubMed

  https://pubmed.ncbi.nlm.nih.gov/30710604/

  Hyperhidrosis (HH) is a dermatologic disorder defined by sweat production exceeding thermoregulatory needs. […] The etiology of HH may stem from a complex autonomic nervous system dysfunction, resulting in neurogenic overactivity of otherwise normal eccrine sweat glands. […] Alternatively, HH may be a result of aberrant central control of emotions. […] This condition is categorized as primary or secondary HH. […] Secondary causes of HH need to be excluded before diagnosing primary HH.

• #1 Hyperhidrosis Clinical Presentation: History, Physical Examination, Complications

  https://emedicine.medscape.com/article/1073359-clinical

  Essential hyperhidrosis is a dermatologic and neurologic disorder characterized by excessive sweating of the eccrine sweat glands. […] Excessive sweating may be primary (idiopathic) or secondary to medication or disease. Secondary causes include endocrine diseases such as diabetes mellitus, hyperthyroidism, and hyperpituitarism. In one series, one third of cases were neurologic in origin, including peripheral nerve injury, Parkinson disease, reflex sympathetic dystrophy, spinal injury, and Arnold-Chiari malformation. Additional causes to consider include pheochromocytoma, respiratory disease, and psychiatric disease. Asymmetric hyperhidrosis may suggest neurologic disease. […] Hyperhidrosis beginning later in life should prompt a search for secondary causes such as systemic diseases, adverse effects of medication use, or metabolic disorders.

• #1 Hyperhidrosis (Excessive Sweating) | Doctor

  https://patient.info/doctor/hyperhidrosis

  Hyperhidrosis (excessive sweating) may be either focal or generalised, and either primary (no underlying cause) or secondary (underlying cause identified). Common triggers include emotion and spicy foods. […] Generalised hyperhidrosis affects the entire body and is usually caused by medical conditions or drugs. […] Causes of hyperhidrosis include pregnancy, anxiety, drugs, substance abuse or withdrawal, heart failure, respiratory failure, infections, malignancy, thyrotoxicosis, and various neurological conditions. […] Secondary focal hyperhidrosis involves specific areas of the body, but is caused by an underlying condition. […] An underlying cause should be suspected if there is generalised sweating, sweating during sleep, or unilateral or asymmetrical sweating. […] Generalised hyperhidrosis is usually due to an underlying disorder. Management is therefore directed at finding and treating any underlying cause.

• #1 Drug-induced hyperhidrosis

  https://dermnetnz.org/topics/drug-induced-hyperhidrosis

  A temporal relationship between initiation of a certain medication and onset of symptoms with no other apparent cause of secondary hyperhidrosis is suggestive of drug-induced hyperhidrosis. […] When suspicious of drug-induced hyperhidrosis, the possible culprit medication should be stopped completely as a trial.

• #1 Hyperhidrosis | Riley Children’s Health

  https://www.rileychildrens.org/health-info/hyperhidrosis

  Hyperhidrosis is excessive sweating. Children with hyperhidrosis sweat as much as five times more than other children. The body’s way of cooling itself (sweating) goes into overdrive for children with hyperhidrosis. As a result, the body makes more sweat than is needed to regulate body temperature. […] There are two kinds of hyperhidrosis: Primary focal hyperhidrosis. Primary focal hyperhidrosis refers to at least one episode each week of excessive sweating in an affected area. […] Secondary hyperhidrosis is caused by another condition such as diabetes, obesity or certain medicines. […] Most children with hyperhidrosis have primary focal hyperhidrosis. […] Treatments for hyperhidrosis include antiperspirants, anticholinergics, iontophoresis, Botox treatments, miraDry and removal of the sweat glands in the underarms.

• #1 Excessive Sweating (Hyperhidrosis) | Cedars-Sinai

  https://www.cedars-sinai.org/health-library/diseases-and-conditions/e/excessive-sweating-hyperhidrosis.html

  Excessive sweating is when the body releases too much fluid from the sweat glands. Its also called hyperhidrosis. […] In most cases, the cause isnt known. This is known as primary hyperhidrosis. But it may be caused by thyroid problems, low blood sugar, nervous system disorders, medicines, or other problems. This is known as secondary hyperhidrosis. […] In some cases, the cause of hyperhidrosis can be serious. […] Hyperhidrosis may be caused by or made worse by emotional stress and heat.

• #2 Hyperhidrosis: Types, Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/17113-hyperhidrosis

  Hyperhidrosis is excessive sweating. This condition happens when you sweat more than what your body needs to regulate your temperature. Hyperhidrosis is the result of your sweat glands overworking. Primary focal hyperhidrosis is a chronic skin condition. A genetic change (mutation) causes this condition. You can inherit it from your biological family. Secondary generalized hyperhidrosis is excessive sweating caused by an underlying medical condition or its a side effect of a medication. Overactive sweat glands cause hyperhidrosis. Research is ongoing to learn more about why your glands make too much sweat. Hyperhidrosis (generalized) could be a sign of an underlying medical condition including but not limited to: Acromegaly, An infection (tuberculosis), Anxiety, Cancer, Diabetes, Heart disease or heart failure, Hyperthyroidism, Menopause, Obesity, Parkinsons disease. Yes, you may be more at risk of hyperhidrosis, specifically focal hyperhidrosis, if someone in your biological family has the condition. Research indicates that a hereditary genetic mutation or change to your DNA could cause hyperhidrosis. […] Certain medications can cause sweating as a side effect, including but not limited to: Albuterol (Proventil), Bupropion (Wellbutrin), Hydrocodone, Insulin (Humulin R, Novolin R), Levothyroxine, Lisinopril, Naproxen (Aleve), Omeprazole (Prilosec), Sertraline (Zoloft).

• #2 Excessive sweating

  https://www.mayoclinic.org/symptoms/excessive-sweating/basics/causes/sym-20050780

  If excessive sweating has no underlying medical cause, it’s called primary hyperhidrosis. It happens when excess sweating is not triggered by a rise in temperature or physical activity. Primary hyperhidrosis may be at least partly hereditary. […] If the excess sweating is due to an underlying medical condition, it’s called secondary hyperhidrosis. […] Health conditions that might cause excessive sweating include: Acromegaly, Diabetic hypoglycemia, Fever of undetermined cause, Hyperthyroidism (overactive thyroid) also known as overactive thyroid, Infection, Leukemia, Lymphoma, Malaria, Medication side effects, such as sometimes experienced when taking some beta blockers and antidepressants, Menopause, Neurologic disease, Pheochromocytoma (a rare adrenal gland tumor), Tuberculosis. […] Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.

• #2 Causes of Excessive Sweating: Primary and Secondary Hyperhidrosis

  https://www.webmd.com/skin-problems-and-treatments/hyperhidrosis-causes-11

  Hyperhidrosis happens when your sweat glands stay on even when you don’t need sweat to cool you down. […] The causes of hyperhidrosis depend on the type of sweating thats happening. Most times, excessive sweating is harmless. In some cases, doctors dont know why people sweat too much. In other cases, the causes of hyperhidrosis may be a medical condition. […] People with primary hyperhidrosis generally sweat from a certain type of gland called eccrine sweat glands. […] Doctors aren’t sure why people have primary hyperhidrosis, although it may be related to the genes you carry. […] Why does it happen? Experts aren’t sure, but primary focal hyperhidrosis seems to stem from a minor malfunction in the sympathetic nervous system. […] This less common form of hyperhidrosis causes sweating all over the body not just on the hands or feet.

• #2 Hyperhidrosis: Causes

  https://www.aad.org/public/diseases/a-z/hyperhidrosis-causes

  Hyperhidrosis is a treatable medical condition that makes people sweat excessively. They sweat more than is needed to cool their body. […] The cause depends on the type of hyperhidrosis you have. There are two types of hyperhidrosis: Primary hyperhidrosis and Secondary hyperhidrosis. […] Its believed that this type of excessive sweating is caused by faulty signals coming from certain nerves, which tell the body when to sweat. Its possible that these nerves over-react, which leads to excessive sweating. […] If youve been diagnosed with secondary hyperhidrosis, the excessive sweating is usually due to one of the following: A medication youre taking or Another medical condition you have. […] Medical conditions that can cause hyperhidrosis include diabetes, Parkinsons disease, and rheumatoid arthritis. Heart failure and stroke can also cause secondary hyperhidrosis, as can menopause.

• #2 Hyperhidrosis: Symptoms, Causes, Treatment

  https://www.health.com/condition/hyperhidrosis-overview

  Hyperhidrosis is the medical term for excessive sweating. The condition can begin in childhood, adolescence, or as an adult. For many people, excessive sweating runs in the family, and problems with sweat are an everyday, normal occurrence. […] Others may notice excess sweat began after taking medication or being diagnosed with a disease like diabetes. However, because hyperhidrosis can affect people physically and psychologically and drastically affect one’s confidence, treatment can improve your quality of life. […] There are two types of hyperhidrosis, primary and secondary, which are diagnosed based on the cause of excessive sweating. […] This type of hyperhidrosis typically begins in childhood or around puberty. Excessive sweating also runs in families; one study found family history in 30 to 50% of primary hyperhidrosis cases.

• #2 Primary and Secondary Hyperhidrosis: Causes

  https://www.verywellhealth.com/hyperhidrosis-causes-4777757

  A common cause of secondary hyperhidrosis is extra body weight and obesity. This is likely due to body heat becoming trapped by adipose tissue, kicking off the body’s natural cooling response, and causing excessive perspiration. […] Several factors related to normal cardiovascular function overlap with hyperhidrosis. The same mechanism that triggers sweating in hyperhidrosis causes an increase in heart rate and blood pressure. […] The sympathetic nervous system, which activates the fight-or-flight response, plays a role in hyperhidrosis. The fight-or-flight response causes an increase in heart rate and blood pressure, which leads to excessive sweating. […] In primary focal hyperhidrosis, sweating usually starts during childhood, which suggests it may be genetic. […] A key difference between the two types is the location of excess sweating. Primary hyperhidrosis typically affects the soles of the feet, the palms of the hands, the underarms (axillary hyperhidrosis), or the face and scalp. People with secondary hyperhidrosis sweat all over.

• #2 Causes of Excessive Sweating: Primary and Secondary Hyperhidrosis

  https://www.webmd.com/skin-problems-and-treatments/hyperhidrosis-causes-11

  One telltale sign of secondary hyperhidrosis is excessive generalized sweating at night. […] Conditions that come with lots of inflammation, such as rheumatoid arthritis (RA), can cause this. […] Excessive sweating usually happens the same on both sides of your body. When it doesn’t, it’s called asymmetric hyperhidrosis. […] When you’re anxious or have an anxiety disorder you may sweat more than other people. […] Uncovering the medical condition that’s causing your hyperhidrosis and getting the proper treatment for it will help lessen the sweating of secondary hyperhidrosis.

• #2 Hyperhidrosis | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/skin-hair-and-nails/hyperhidrosis/

  Some cases of primary hyperhidrosis appear to run in families, which suggests a genetic mutation may be the cause. […] If a cause of hyperhidrosis can be identified, its known as secondary hyperhidrosis. […] Secondary hyperhidrosis can have a number of different triggers, including: pregnancy, the menopause when a womans monthly periods stop, anxiety, low blood sugar (hypoglycaemia), an overactive thyroid gland (hyperthyroidism), obesity, certain medications including some antidepressants, propranolol, pilocarpine, and bethanechol, being drunk or high on drugs, or withdrawing from alcohol or drugs if you have become addicted to them, some infections, such as tuberculosis and HIV, Parkinsons disease, disorders of the blood cells or bone marrow, such as Hodgkin lymphoma.

• #2 Diaphoresis: Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/24496-diaphoresis

  When your thyroid becomes overactive, it makes too much of a hormone called thyroxine. This is called hyperthyroidism. […] If you have diabetes, excessive sweating may be a sign of low blood sugar (hypoglycemia). […] Excessive sweating is one of the most common signs of a heart attack (myocardial infarction). […] Diaphoresis is a common symptom of substance withdrawal. […] Certain cancers and cancer treatments can cause excessive sweating. […] Severe allergic reactions to triggers such as peanuts, shellfish or bee stings can cause anaphylaxis. […] Certain prescription and over-the-counter (OTC) medications can cause side effects that include excessive sweating.

• #2 Generalized Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/causes-of-secondary-hyperhidrosis/generalized-hyperhidrosis.html

  Generalized hyperhidrosis is usually secondary to an underlying medical condition or can have a physiological basis with heat, humidity, or exercise, leading to excessive sweating out of proportion to thermoregulatory needs. […] Infections, neoplasia, metabolic and endocrine disorders, high catecholamine states, drug therapy, and neurologic problems can all be associated with systemic hyperhidrosis. […] Endocrine disorders associated with hyperhidrosis include thyrotoxicosis, hyperpituitarism, diabetes mellitus, pheochromocytoma, hypoglycemia, gout, and menopause. […] Excessive sweating, tachycardia, and headache in a patient with hyperhidrosis should raise suspicion of pheochromocytoma and prompt measurement of catecholamine levels. […] Acute and chronic infections and neoplasia can lead to fever followed by excessive sweating.

• #2 Hyperhidrosis: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/007259.htm

  Hyperhidrosis is a medical condition in which a person sweats excessively and unpredictably. […] Excessive sweating occurs without such triggers. People with hyperhidrosis appear to have overactive sweat glands. […] When excessive sweating affects the hands, feet, and armpits, it is called focal hyperhidrosis. In most cases, no cause can be found. It seems to run in families. […] Sweating that is not caused by another disease is called primary hyperhidrosis. […] If the sweating occurs as a result of another medical condition, it is called secondary hyperhidrosis. […] Conditions that cause secondary hyperhidrosis include: Acromegaly, Anxiety conditions, Cancer, Carcinoid syndrome, Certain medicines and substances of abuse, Glucose control disorders (diabetes and hypoglycemia), Heart disease, such as heart attack, Overactive thyroid, Lung disease, Menopause, Parkinson disease, Pheochromocytoma (adrenal gland tumor), Spinal cord injury, Stroke, Tuberculosis or other infections.

• #2 Hyperhidrosis – Wikipedia

  https://en.wikipedia.org/wiki/Hyperhidrosis

  Certain endocrine conditions are also known to cause secondary hyperhidrosis including diabetes mellitus (especially when blood sugars are low), acromegaly, hyperpituitarism, pheochromocytoma (tumor of the adrenal glands, present in 71% of patients) and various forms of thyroid disease. […] Use of selective serotonin reuptake inhibitors (e.g., sertraline) is a common cause of medication-induced secondary hyperhidrosis. Other medications associated with secondary hyperhidrosis include tricyclic antidepressants, stimulants, opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), glyburide, insulin, anxiolytic agents, adrenergic agonists, and cholinergic agonists. […] In people with a history of spinal cord injuries, autonomic dysreflexia, orthostatic hypotension, and posttraumatic syringomyelia can be associated with hyperhidrosis.

• #2 Reddit – The heart of the internet

  https://www.reddit.com/r/Hyperhidrosis/comments/1gk2d71/what_causes_hyperhidrosis/

  Nervous system disorders: Conditions like Parkinsons disease, spinal cord injuries, or strokes may lead to excessive sweating due to nerve dysregulation. […] Heart conditions: Heart attacks or heart failure can sometimes trigger excessive sweating. […] Obesity: Higher body mass can increase sweat production as the body tries to regulate its temperature. […] Anxiety and stress: Stress activates the bodys „fight-or-flight” response, which can lead to increased sweating, particularly in people with hyperhidrosis. […] Medications that can cause increased sweating as a side effect include antidepressants, opioids, certain blood pressure drugs, and some diabetes medications.

• #2 Focal Secondary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/causes-of-secondary-hyperhidrosis/focal-hyperhidrosis.html

  A variety of diseases can cause localized hyperhidrosis. Neurologic injury and dermatologic syndromes make up the majority of secondary causes of excessive focal sweat production. Acute spinal cord injury would be expected to lead to loss of sweating below the site of injury, but such injuries can also lead to localized areas of hyperhidrosis seen months to years after the injury. […] Central nervous system injuries such as strokes leading to hemispheric or medullary infarcts can lead to hyperhidrosis on the ipsilateral and contralateral side, respectively. […] An intrathoracic tumor impinging on the sympathetic trunk or postganglionic nerves can cause hyperhidrosis by a similar mechanism. […] In reflex sympathetic dystrophy, hyperhidrosis is often seen in the affected area. […] Compensatory hyperhidrosis is also seen in diabetic neuropathy, after thoracic sympathectomy (ETS), and in Ross syndrome, a rare syndrome in which anhidrosis occurs in a dermatomal pattern due to focal dysfunction of the sympathetic fibers innervating sweat glands.

• #2 Focal Secondary Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/causes-of-secondary-hyperhidrosis/focal-hyperhidrosis.html

  It should be noted that compensatory sweating after ETS for the treatment of hyperhidrosis has been reported as potentially being as severe or more severe than the original sweating problem and may require treatment in itself. […] Conditions sometimes associated with palmoplantar hyperhidrosis include Raynauds disease, erthromelalgia, atrioventricular fistula, cold injury, rheumatoid arthritis, and some rare dermatologic syndromes. […] After inflammation or surgery near the parotid gland, cross-talk between regenerating nerves that cause salivation and sympathetic nerves causes excessive facial sweating.

• #2 Hyperhidrosis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/1073359-overview

  Chronic alcoholism […] Hodgkin disease or tuberculosis (in nocturnal hyperhidrosis) […] Localized unilateral or segmental hyperhidrosis is rare and of unknown origin. […] Primary focal hyperhidrosis tends to arise on the palms, plantar feet, and axillae, as well as from the face and scalp of children and young adults; there seems to have a distinct subtype of craniofacial hyperhidrosis in postmenopausal women. […] Unilateral hyperhidrosis with accompanying contralateral anhidrosis is also rare. […] Localized hyperhidrosis may also be associated with the following: Gustatory stimuli (associated with Frey syndrome, encephalitis, syringomyelia, diabetic neuropathies, herpes zoster parotitis, and parotid abscess) […] Eccrine nevus: This may be associated with severe localized hyperhidrosis. […] Eccrine angiomatous hamartoma: This is a rare, benign malformation characterized by both eccrine and vascular components. […] Spinal cord tumors: Rarely, hyperhidrosis may be an initial symptom.

• #2 7 Causes of Excessive Sweating – The Dermatology Group | Dermatology

  https://thedermgrouppartners.com/7-causes-of-excessive-sweating/

  1) Primary hyperhidrosis is a condition in which your sweat glands are activated thanks to overactive nerves. This particular condition has no known medical cause and may be the result of heredity. […] 2) Fever can cause sweating. This happens when your body is fighting some type of infection causing your body temperature to increase. […] 3) Individuals who have diabetes and find themselves sweating excessively may have diabetic hypoglycemia. […] 4) Hyperthyroidism is a condition in which your thyroids are producing too much thyroxine. […] 5) Sudden excessive sweating is a very common sign of an oncoming heart attack. […] 6) Excessive nighttime sweating is among the symptoms of leukemia. […] 7) Being overweight causes many problems as it forces the body to work double-time in order to function properly. This often causes excessive sweating.

• #2 Reddit – The heart of the internet

  https://www.reddit.com/r/Hyperhidrosis/comments/1gk2d71/what_causes_hyperhidrosis/

  Hyperhidrosis, or excessive sweating, can be caused by several factors, and its often classified into two main types based on the cause: […] The exact cause isnt fully understood, but its believed to be related to overactivity of the sympathetic nervous system, which controls sweat glands. […] This form of hyperhidrosis often runs in families, suggesting a genetic component. […] This type of hyperhidrosis is caused by an underlying medical condition or a side effect of medication. […] Common medical conditions that can cause secondary hyperhidrosis include: […] Endocrine disorders: Hyperthyroidism, diabetes, and menopause (hot flashes) can increase sweating. […] Infections: Tuberculosis and HIV are examples of infections that may cause excessive sweating, especially night sweats.

• #2 Hyperhidrosis Disorder (Excessive Sweating)

  https://www.healthline.com/health/hyperhidrosis

  Hyperhidrosis causes excessive sweating beyond what your body needs for temperature regulation. […] Focal hyperhidrosis is linked to overactive cholinergic receptors in sweat glands. Generalized hyperhidrosis is associated with conditions like diabetes, hyperthyroidism, substance use, and Parkinsons disease. […] The exact cause of hyperhidrosis is unknown, but it may be passed down in families. […] Secondary generalized hyperhidrosis is excessive sweating caused by a medical condition or as a side effect of certain medications. […] Conditions that may cause this type include: diabetes, hyperthyroidism, Parkinsons disease, cancer, menopause, infectious diseases, such as tuberculosis or HIV, alcohol use disorder, heart disease, adrenal gland disorders, stroke, withdrawal from prescription or illegal drugs. […] Several types of prescription and over-the-counter (OTC) medications can cause hyperhidrosis as well. This may include some types of: antidepressants, antipsychotics, antibiotics, insulin. […] Secondary generalized hyperhidrosis occurs due to certain medical conditions and medications.

• #2 Diaphoresis: Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/24496-diaphoresis

  Diaphoresis means excessive sweating due to a secondary condition. It may be a medical condition, life event or side effect of a medication. Common causes include menopause, hyperthyroidism and various medications. […] Diaphoresis is the medical definition of excessive sweating due to an underlying health condition or a medication. Another name for diaphoresis is secondary hyperhidrosis. Hyperhidrosis means excessive sweating. Secondary means you’re sweating because of a separate condition. Primary hyperhidrosis means another condition isn’t causing the sweating. […] Diaphoresis means abnormal sweating due to a secondary condition. Causes of diaphoresis may include: […] Menopause is one of the most common causes of diaphoresis in women. […] Diaphoresis is also a common condition during pregnancy.

• #2 What Causes Excessive Sweating?

  https://worcesterderm.com/what-causes-excessive-sweating/

  Gout is known to cause hyperhidrosis. If the onset of your hyperhidrosis symptoms correlates with a gout diagnosis, that could be a sign that your hyperhidrosis is a secondary condition. […] Some forms of nerve damage or head trauma may affect your body’s ability to regulate sweat production. […] Frostbite can cause permanent damage to the body, including temperature sensitivity and an increased likelihood of developing hyperhidrosis. […] Carrying extra weight means the body has to work harder during physical activities, making patients who struggle with obesity more likely to get easily overheated. […] Patients with hyperthyroidism are often more sensitive to heat when compared to patients who have a properly functioning thyroid. […] Some types of tumors or cancers can contribute to night sweats in particular. […] If you’re struggling with hyperhidrosis as a primary condition, you’re likely to have developed it early on in life. Primary hyperhidrosis is more likely to affect specific areas of the body, rather than the whole body at once.

• #2 Hyperhidrosis (Excessive Sweating): Causes, Medication & Treatment

  https://www.emedicinehealth.com/hyperhidrosis_excessive_sweating/article_em.htm

  Hyperhidrosis is sweating in excess of that normally required to regulate the body temperature. Hyperhidrosis can be primary hyperhidrosis without underlying medical conditions associated or it can be secondary to other medical conditions. Primary hyperhidrosis is caused by excessive activity of the sweat glands and is associated with overactivity of a branch of the involuntary nervous system (the sympathetic nervous system). Secondary, or acquired, hyperhidrosis is usually generalized and has a variety of causes and presentations. These include metabolic disorders, hormonal changes, medication reactions, neurologic disease, and certain tumors. […] For primary axillary or palmoplantar hyperhidrosis, the main risk factor would be other first-order relatives with a similar condition. Besides febrile illness, the main diseases to be considered for patients with generalized secondary hyperhidrosis are tuberculosis, chronic alcoholism, hyperthyroidism, gout, diabetes, multiple myeloma, and pheochromocytoma. Neurologic diseases such as stroke, tabes dorsalis (syphilis), spinal injury, and Parkinson’s disease have also been associated with excessive sweating. […] Primary hyperhidrosis can run in families and usually becomes significant at or somewhat before puberty. Secondary hyperhidrosis can begin at any age.

• #2 Excessive Sweating Causes | Primary & Secondary Hyperhidrosis Causes

  https://resources.healthgrades.com/right-care/skin-hair-and-nails/6-causes-of-excessive-sweating

  6 Causes of Excessive Sweating […] Although sometimes embarrassing, sweating is a natural response when your body needs to cool itself, such as in warm weather or while exercising. […] However, some people experience excessive sweating when none of these situations applies. This is called hyperhidrosis. […] Primary focal hyperhidrosis causes are often unknown, but many dermatologists believe the root could be genetic. […] You may experience secondary hyperhidrosis as a side effect of a medication you’re taking to treat a different medical condition. […] Unlike primary hyperhidrosis, secondary hyperhidrosis can be a symptom of another condition, rather than the condition itself. […] One medical condition that includes excessive sweating as a symptom is diabetic hypoglycemia. […] Hot flashes and sudden sweatiness are common and well-known menopause symptoms. […] Excessive sweating is one symptom of hyperthyroidism. […] In some cases, excessive sweating causes someone to develop anxiety, and in other cases, social anxiety disorder may cause hyperhidrosis.

• #2 Hyperhidrosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459227/

  Hyperhidrosis can be categorized as either primary or secondary. This distinction is important because treatment and management may significantly differ between the two groups. The etiology of primary hyperhidrosis remains unknown despite multiple literature reviews. Genetic factors are believed to play a role in excessive neural stimulation, although this is poorly understood. Secondary causes are usually easier to identify because they are associated with medications such as dopamine agonists, selective serotonin reuptake inhibitors (SSRIs), antipsychotics, and insulin; systemic disorders such as diabetes mellitus, hyperthyroidism, Parkinson disease, and other neurologic disorders; and tumors such as pheochromocytoma and lymphoma. […] Almost any febrile illness can cause hyperhidrosis. Chronic excessive alcohol consumption and tuberculosis are also associated with hyperhidrosis. Developing segmental or localized hyperhidrosis is rare. The condition can present on some adults’ forehead, axilla, palm, feet, or forearm. Some postmenopausal women develop moderate to severe hyperhidrosis around their face and scalp. Unilateral hyperhidrosis tends to be more common on the right side of the face or arm, with anhidrosis on the left side.

• #2 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Hyperhidrosis-Causes.aspx

  When the cause of the condition is clear, the condition is called secondary hyperhidrosis. The onset of secondary hyperhidrosis is often more sudden than the onset of primary hyperhidrosis and is likely to cause sweating across the whole body. This can be triggered by many underlying factors, including the following: menopause, pregnancy, anxiety, low blood sugar or hypoglycemia, hyperthyroidism, diabetes, obesity, some medications such as anti-depressants and the beta-blockers, certain infections, including HIV and tuberculosis, Parkinson’s disease, disorders of the blood cell or bone marrow including Hodgkin lymphoma.

• #2 Generalized Hyperhidrosis – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/about-hyperhidrosis/causes-of-secondary-hyperhidrosis/generalized-hyperhidrosis.html

  Conditions associated with high sympathetic discharge can lead to excessive sweating. […] Drugs reported to cause hyperhidrosis include propanolol, physostigmine, pilocarpine, tricyclic antidepressants, fluoxetine, venlafaxine, and cyclobenzaprine, but there are more, as well. […] Familial dysautonomia, or Riley-Day syndrome, can lead to generalized hyperhidrosis. […] Hyperhidrosis has been seen without hyperthermia in patients with a hypothalamic stroke.

• #2 Hyperhidrosis Explained: Why Some Sweat More | Parfaire

  https://www.parfaire.com/blog/hyperhidrosis-explained-why-some-people-sweat-more-than-others/

  Unlike primary hyperhidrosis, which occurs without a medical cause, secondary hyperhidrosis is linked to an underlying medical condition. Several health issues can lead to increased sweating, including: Diabetes, Low blood sugar (hypoglycemia) can trigger excessive sweating. Hyperthyroidism, An overactive thyroid can increase metabolism and sweat production. Menopause, Hormonal changes can cause hot flashes and sweating. Infections, Conditions like tuberculosis and endocarditis can result in night sweats. Neurological disorders, Parkinson’s disease and stroke can affect sweat regulation. […] Certain external factors can also contribute to excessive sweating. These include: Heat and humidity, Hot weather naturally triggers the sweat glands, making sweating worse for those prone to hyperhidrosis. Dietary triggers, Spicy foods, caffeine, and alcohol can stimulate sweat production. Stress and anxiety, Emotional stress can activate the nervous system, increasing sweat output, particularly in people with hyperhidrosis. Medications, Some drugs, including antidepressants and pain relievers, can cause excessive sweating as a side effect.

• #2 Hyperhidrosis: types, causes and treatment of hyperhidrosis

  https://institutomedicolaser.com/hyperhidrosis-types-causes-and-treatment/

  Hyperhidrosis is the excessive sweating or perspiration that occurs spontaneously, not caused by high temperatures or physically and emotionally tense situations. […] The cause of primary hyperhidrosis is unknown. […] It is clearly related to sympathetic over-activity and an excessive sudomotor function response. […] Certain habits, such as drinks, nicotine, caffeine and certain foods or smells can also trigger excessive sweating. […] Secondary hyperhidrosis is usually generalised and presents itself within the symptoms of an underlying condition: spinal cord injuries, peripheral neuropathies, brain lesions, intrathoracic tumoral lesions, systemic disorders (pheochromocytoma, Parkinson’s disease, thyrotoxicosis, among others), mercury poisoning. […] Excessive sweating of up to 100 cm2 can be related with the presence of (among others): glomus tumour, blue rubber bleb naevus, pachydermoperiostosis, diabetic nephropathy, parotitis, parotid abscesses.

• #2 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Hyperhidrosis is excessive sweating that affects patients’ quality of life, resulting in social and work impairment and emotional distress. Primary hyperhidrosis is bilaterally symmetric, focal, excessive sweating of the axillae, palms, soles, or craniofacial region not caused by other underlying conditions. Secondary hyperhidrosis may be focal or generalized, and is caused by an underlying medical condition or medication use. […] The cause of primary hyperhidrosis is not well understood. Eccrine sweat glands distributed throughout the body, but heavily concentrated on the palms, soles, axillae, and face are innervated by postganglionic autonomic nerve fibers and stimulated by the neurotransmitter acetylcholine. It is thought that increased or aberrant sympathetic stimulation of the eccrine sweat glands is responsible for the increased sweating rather than an increased number or size of the glands. […] Persons with primary hyperhidrosis have a higher-than-normal basal level of sweat production and an increased response to normal stimuli, such as emotional or physical stress.

• #2 Hyperhidrosis: Causes, Symptoms, and Treatment | RoRoRo

  https://ro.co/hyperhidrosis/hyperhidrosis-causes-symptoms-and-treatment/

  Hyperhidrosis is a medical condition characterized by excessive sweating. […] In hyperhidrosis, you sweat more than usual and often without the typical triggers. One theory to explain hyperhidrosis is that there may be an abnormally increased release of acetylcholine, or that the nerve signals cannot be turned off appropriately. […] There are two types of hyperhidrosis: primary focal hyperhidrosis and secondary generalized hyperhidrosis. […] Primary hyperhidrosis is not caused by another medical condition or medications that you may be taking; excessive sweating is the medical condition. […] Secondary hyperhidrosis differs because it is excessive sweating that is caused by a medical condition, such as hyperthyroidism, diabetes, or menopause; it can also be due to medication side effects.

• #2 Hyperhidrosis Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/diseases-conditions/hyperhidrosis

  Hyperhidrosis is a medical condition in which a person sweats excessively and unpredictably. People with hyperhidrosis may sweat even when the temperature is cool or when they are at rest. […] Excessive sweating occurs without such triggers. People with hyperhidrosis appear to have overactive sweat glands. The uncontrollable sweating can lead to significant discomfort, both physical and emotional. […] When excessive sweating affects the hands, feet, and armpits, it is called focal hyperhidrosis. In most cases, no cause can be found. It seems to run in families. […] Sweating that is not caused by another disease is called primary hyperhidrosis. […] If the sweating occurs as a result of another medical condition, it is called secondary hyperhidrosis. The sweating may be all over the body (generalized) or it may be in one area (focal). Conditions that cause secondary hyperhidrosis include: Acromegaly, Anxiety conditions, Cancer, Carcinoid syndrome, Certain medicines and substances of abuse, Glucose control disorders (diabetes and hypoglycemia), Heart disease, such as heart attack, Overactive thyroid, Lung disease, Menopause, Parkinson disease, Pheochromocytoma (adrenal gland tumor), Spinal cord injury, Stroke, Tuberculosis or other infections.

• #2 Drug-induced hyperhidrosis

  https://dermnetnz.org/topics/drug-induced-hyperhidrosis

  Different classes of medications can influence the sweating response by acting centrally in the brain and the peripheral nervous system. […] Medications used to treat psychiatric conditions that can cause hyperhidrosis include: Selective serotonin reuptake inhibitors (SSRIs), such as citalopram; Tricyclic antidepressants, such as amitriptyline; Antipsychotics, such as haloperidol and clozapine. […] Medications that can affect endocrine function and thus cause hyperhidrosis can include: Systemic corticosteroids; Thyroid medications; Diabetic medications such as glipizide and insulin. […] Withdrawal from non-prescription drugs such as alcohol and caffeine can also cause generalised hyperhidrosis. […] Drug-induced hyperhidrosis is diagnosed clinically. Other causes of secondary hyperhidrosis should be excluded, such as an underlying infection, malignancy, neurological, or endocrine conditions.

• #2 Will My Excessive Sweating Condition Resolve on Its Own? | HK Dermatology

  https://kleinmd.com/will-my-excessive-sweating-condition-resolve-on-its-own/

  Theres no doubt about it excessive sweating is embarrassing. […] This condition, called hyperhidrosis, causes visible sweat on your skin that can show through your clothes. […] Most people have primary hyperhidrosis, which usually begins in adolescence in otherwise healthy individuals. Less commonly, people may develop secondary hyperhidrosis, which results from a medical condition or side effect of a medication. […] Unfortunately, there is no cure for primary hyperhidrosis. […] For people with secondary hyperhidrosis, the condition may improve once the underlying condition is treated or managed or if the medication triggering the sweating is stopped.

• #2 Hyperhidrosis – Dermatologic Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/dermatologic-disorders/sweating-disorders/hyperhidrosis

  Although generalized sweating is usually normal, consider cancer, infection, and endocrine disorders as directed by patient symptoms. […] Hyperhidrosis can be primary or secondary to an underlying medical condition. […] Compensatory hyperhidrosis is most common after endoscopic transthoracic sympathectomy, developing in up to 80% of patients.

• #2 Content – Health Encyclopedia – University of Rochester Medical Center

  https://www.urmc.rochester.edu/encyclopedia/content?ContentTypeID=85&ContentID=P00284

  Excessive sweating is when the body releases too much fluid from the sweat glands. Its also called hyperhidrosis. In most cases, the cause isnt known. This is known as primary hyperhidrosis. But it may be caused by thyroid problems, low blood sugar, nervous system disorders, medicines, or other problems. This is known as secondary hyperhidrosis. In some cases, the cause of hyperhidrosis can be serious. […] Excessive sweating can affect the entire body, but it usually occurs in the palms, soles, armpits, or groin area. […] In most cases, the cause isnt known. It may be caused by thyroid problems, low blood sugar, nervous system disorders, medicines, or other problems. […] Hyperhidrosis may be caused by or made worse by emotional stress and heat.

• #3 Excessive Sweating (Hyperhidrosis) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/excessive-sweating

  Excessive sweating that can get in the way of daily life and cause skin infections. […] In people with hyperhidrosis, the body’s 2 to 4 million sweat glands are overactive, causing profuse perspiration at times when others would sweat lightly (if at all). […] Sometimes, however, hyperhidrosis can be caused by disorders of the thyroid, menopause, or certain medications. […] This type of hyperhidrosis can happen in one or two locations on the body, or it can affect the entire body. It results from some medications or from a medical condition. […] Hyperhidrosis tends to run in families. […] Some medical conditions (like menopause) may cause sweating. […] Certain medications can cause excessive sweating.

• #3 Hyperhidrosis | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/skin-hair-and-nails/hyperhidrosis/

  Hyperhidrosis can be divided into 2 types, depending on whether an obvious cause can be identified. These are known as primary and secondary hyperhidrosis. […] In many cases, hyperhidrosis has no obvious cause and is thought to be the result of a problem with the part of the nervous system that controls sweating. This is known as primary hyperhidrosis. […] Hyperhidrosis that does have an identifiable cause is known as secondary hyperhidrosis. This can have many different triggers, including: pregnancy or the menopause, anxiety, certain medications, low blood sugar (hypoglycaemia), an overactive thyroid gland (hyperthyroidism), infections. […] Although its not clear why it develops, its thought to be the result of a problem with part of the nervous system called the sympathetic nervous system, and its possible your genes may also play a role.

• #3 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Hyperhidrosis-Causes.aspx

  Hyperhidrosis is classified into 2 types, based on whether the reason behind the condition can be found. The 2 types are primary hyperhidrosis or secondary hyperhidrosis and these are described in more detail below. […] Primary hyperhidrosis is the term used when no obvious identifiable cause for the excessive sweating can be identified. The condition is thought to be caused by an issue in the sympathetic nervous system (SNS), which regulates sweating. In this case, it is possible that there may be a genetic element to the condition. […] It is possible that a hereditary element involving genetic mutation may be the cause of primary hyperhidrosis, since it appears to run in some families. When genetic mutation occurs, the instructions in the cells that control the normal body function become scrambled, resulting in disruption of the body’s usual workings.

• #3 Hyperhidrosis: Causes

  https://www.aad.org/public/diseases/a-z/hyperhidrosis-causes

  Parkinsons can affect the part of the nervous system that controls sweating. Excessive sweating can worsen as Parkinsons progresses. […] Unlike primary hyperhidrosis, secondary hyperhidrosis can cause you to sweat while youre asleep. […] You may develop secondary hyperhidrosis if you have one of the following: Take medication (described above) that can cause excessive sweating or Have a medical condition (described above) that can lead to excessive sweating. […] The etiology, diagnosis, and management of hyperhidrosis: A comprehensive review: Etiology and clinical work-up.

• #3 Hyperhidrosis: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/007259.htm

  Hyperhidrosis is a medical condition in which a person sweats excessively and unpredictably. […] Excessive sweating occurs without such triggers. People with hyperhidrosis appear to have overactive sweat glands. […] When excessive sweating affects the hands, feet, and armpits, it is called focal hyperhidrosis. In most cases, no cause can be found. It seems to run in families. […] Sweating that is not caused by another disease is called primary hyperhidrosis. […] If the sweating occurs as a result of another medical condition, it is called secondary hyperhidrosis. […] Conditions that cause secondary hyperhidrosis include: Acromegaly, Anxiety conditions, Cancer, Carcinoid syndrome, Certain medicines and substances of abuse, Glucose control disorders (diabetes and hypoglycemia), Heart disease, such as heart attack, Overactive thyroid, Lung disease, Menopause, Parkinson disease, Pheochromocytoma (adrenal gland tumor), Spinal cord injury, Stroke, Tuberculosis or other infections.

• #3 Hyperhidrosis – Wikipedia

  https://en.wikipedia.org/wiki/Hyperhidrosis

  Certain endocrine conditions are also known to cause secondary hyperhidrosis including diabetes mellitus (especially when blood sugars are low), acromegaly, hyperpituitarism, pheochromocytoma (tumor of the adrenal glands, present in 71% of patients) and various forms of thyroid disease. […] Use of selective serotonin reuptake inhibitors (e.g., sertraline) is a common cause of medication-induced secondary hyperhidrosis. Other medications associated with secondary hyperhidrosis include tricyclic antidepressants, stimulants, opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), glyburide, insulin, anxiolytic agents, adrenergic agonists, and cholinergic agonists. […] In people with a history of spinal cord injuries, autonomic dysreflexia, orthostatic hypotension, and posttraumatic syringomyelia can be associated with hyperhidrosis.

• #3 Hyperhidrosis – Dermatologic Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/dermatologic-disorders/sweating-disorders/hyperhidrosis

  Hyperhidrosis can be focal or generalized. […] Emotional causes are common, causing sweating on the palms, soles, axillae, and forehead at times of anxiety, excitement, anger, or fear. […] Pathologic causes include diabetic neuropathy, facial herpes zoster, cervical sympathetic ganglion invasion, central nervous system injury or disease, or parotid gland injury. […] Frey syndrome is a neurologic condition due to injury to or around the parotid glands resulting from surgery, infection, or trauma. […] Other causes of focal sweating include pretibial myxedema (shins), hypertrophic osteoarthropathy (palms), blue rubber bleb nevus syndrome, and glomus tumor (over lesions). […] Generalized sweating involves most of the body. Although most cases are idiopathic, numerous conditions can be involved.

• #3 Hyperhidrosis – Wikipedia

  https://en.wikipedia.org/wiki/Hyperhidrosis

  Hyperhidrosis is a medical condition in which a person exhibits excessive sweating, more than is required for the regulation of body temperature. […] The cause of primary hyperhidrosis is unknown. Anxiety or excitement can exacerbate the condition. A common complaint of people is a nervous condition associated with sweating, then sweat more because the person is nervous. Other factors can play a role, including certain foods and drinks, nicotine, caffeine, and smells. […] Similarly, secondary (generalized) hyperhidrosis has many causes including certain types of cancer, disturbances of the endocrine system, infections, and medications. […] Primary (focal) hyperhidrosis has many causes. […] A variety of cancers have been associated with the development of secondary hyperhidrosis including lymphoma, pheochromocytoma, carcinoid tumors (resulting in carcinoid syndrome), and tumors within the thoracic cavity.

• #3 Generalised Hyperhidrosis |

  https://sydneynorthneurology.com.au/generalised-hyperhidrosis/

  Generalised hyperhidrosis usually begins in adulthood due to medical comorbidity; that is, a disease which causes the excessive sweating (e.g. infection). It typically resolves following treatment of the comorbid condition. […] Generalised hyperhidrosis affects the entire body and typically occurs diurnally (in the day) and nocturnally. Following a diagnosis of generalised or secondary hyperhidrosis, further tests are used to diagnose the underlying medical condition/s, as treating these conditions is the only way to reduce the excessive sweating. […] Because generalised hyperhidrosis usually arises secondary to a medical condition, investigation and treatment of the underlying condition is the first step in the management process. It is usually sufficient to resolve the underlying condition and excessive sweating symptoms.

• #4 Hyperhidrosis: Causes, Symptoms, and Treatment | RoRoRo

  https://ro.co/hyperhidrosis/hyperhidrosis-causes-symptoms-and-treatment/

  In primary focal hyperhidrosis, there is no specific cause. […] Secondary hyperhidrosis, by definition, is caused by a specific condition or side effect of a medication. Potential medical conditions that cause this include (Romero, 2016): Hyperthyroidism, Diabetes, Menopause (hot flashes), Pregnancy, Parkinson’s disease, Nerve injury, Chronic lung disease, Cancer, Tuberculosis, Human immunodeficiency virus (HIV). […] Also, several drugs have excessive sweating as a potential side effect; these drugs include (McConaghy, 2018): Selective-serotonin reuptake inhibitors (SSRIs), like fluoxetine, Selective-norepinephrine reuptake inhibitors (SNRIs), like venlafaxine, Pyridostigmine, Insulin, Sulfonylureas, like glipizide, Thiazolidinediones, like rosiglitazone, Raloxifene, Tamoxifen, Infliximab, Sildenafil, Opioid withdrawal.

Zobacz więcej