Kurczowe zapalenie skóry na zimno
Zapobieganie i profilaktyka

Kurczowe zapalenie skóry na zimno (cold urticaria) to pokrzywka fizykalna manifestująca się bąblami pokrzywkowymi i/lub obrzękiem naczynioruchowym po ekspozycji na zimno. Profilaktyka opiera się przede wszystkim na unikaniu ekspozycji na niskie temperatury, zimną wodę, zimne pokarmy i napoje oraz przedmioty o niskiej temperaturze. Zalecane jest noszenie ciepłej odzieży, unikanie gwałtownych zmian temperatury oraz ostrożność podczas aktywności wodnych i na świeżym powietrzu. Leki przeciwhistaminowe drugiej generacji (np. cetyryzyna, loratadyna, desloratadyna, lewocetyryzyna, feksofenadyna) stosowane profilaktycznie przed ekspozycją na zimno są podstawą farmakoterapii. W razie nieskuteczności standardowych dawek dopuszcza się ich zwiększenie do czterokrotności. W terapii opornej rozważa się omalizumab, hydroksyzynę, doksepinę, ketotifen, cyproheptadynę oraz antagonistów receptorów leukotrienowych.

Profilaktyka kurczowego zapalenia skóry na zimno

Kurczowe zapalenie skóry na zimno (cold urticaria) to schorzenie charakteryzujące się występowaniem bąbli pokrzywkowych i/lub obrzęku naczynioruchowego po ekspozycji skóry na zimno. Jest to jedna z podkategorii pokrzywek fizykalnych, która może wywoływać reakcje miejscowe lub ogólnoustrojowe. Ponieważ nie istnieje skuteczna metoda całkowitego wyleczenia tego schorzenia, kluczowe znaczenie ma profilaktyka i zapobieganie występowaniu objawów.123

Unikanie ekspozycji na zimno

Podstawową i najskuteczniejszą metodą profilaktyki kurczowego zapalenia skóry na zimno jest unikanie ekspozycji na zimno. Dotyczy to zarówno niskich temperatur otoczenia, zimnej wody, zimnych pokarmów i napojów, jak również przedmiotów o niskiej temperaturze.456

Zalecane działania profilaktyczne obejmują:78

  • Noszenie odpowiedniej, ciepłej odzieży podczas zimnych miesięcy (ciepłe kurtki, czapki, rękawiczki, szaliki) i maksymalne ograniczenie ekspozycji skóry na zimne powietrze910
  • Unikanie lub ograniczenie przebywania w miejscach o niskiej temperaturze otoczenia (piwnice, lodowiska, supermarkety z lodówkami)1112
  • Sprawdzanie temperatury wody przed zanurzeniem – przed kąpielą w basenie zaleca się zanurzenie najpierw ręki w wodzie, aby sprawdzić, czy występuje reakcja skórna1314
  • Unikanie zimnych napojów i produktów mrożonych (lody, zimne napoje z lodem), które mogą powodować obrzęk gardła1516
  • Korzystanie z wody o temperaturze pokojowej lub letniej do mycia rąk i kąpieli1718
  • Unikanie gwałtownych zmian temperatury – ogrzewanie się stopniowo po ekspozycji na zimno19
  • Unikanie zajęć domowych takich jak rozmrażanie zamrażarki czy mycie okien zimną wodą20

Aktywności wysokiego ryzyka

Szczególną ostrożność należy zachować podczas aktywności związanych z ekspozycją na zimno, zwłaszcza tych z potencjalnym ryzykiem reakcji systemowych.2122

  • Unikanie lub podejmowanie ze szczególną ostrożnością aktywności wodnych (pływanie w zimnej wodzie, surfing) – nigdy nie pływać samemu, zawsze pod nadzorem2324
  • Ograniczenie aktywności na świeżym powietrzu w zimnych warunkach pogodowych, zwłaszcza sportów zimowych i wspinaczki górskiej25
  • Planowanie z wyprzedzeniem – sprawdzanie prognozy pogody i przygotowanie odpowiednich środków zaradczych (ciepłe napoje, poduszki grzewcze, ciepłe koce)26

Farmakologiczne metody profilaktyki

Leki przeciwhistaminowe

Leki przeciwhistaminowe odgrywają kluczową rolę w profilaktyce kurczowego zapalenia skóry na zimno. Blokują one uwalnianie histaminy, która powoduje objawy. Zaleca się przyjmowanie tych leków przed planowaną ekspozycją na zimno, aby zapobiec wystąpieniu reakcji.2728

Najczęściej stosowane leki to:2930

W przypadku braku skuteczności standardowych dawek leków przeciwhistaminowych, lekarz może zalecić zwiększenie dawki (nawet do czterokrotności standardowej dawki) bez istotnego zwiększenia ryzyka działań niepożądanych.313233

Ważne jest, aby leki przeciwhistaminowe przyjmować regularnie, a nie doraźnie, co zapewnia lepszą kontrolę objawów.3435

Leki drugiego rzutu

W przypadku niewystarczającej skuteczności leków przeciwhistaminowych, lekarz może zalecić:3637

Autostrzykawka z adrenaliną

Pacjenci z kurczowym zapaleniem skóry na zimno, u których występowało ryzyko reakcji anafilaktycznej, powinni zawsze mieć przy sobie autostrzykawkę z adrenaliną (epinefryną).464748

Adrenalina pomaga powstrzymać anafilaksję i złagodzić objawy. Jest to szczególnie ważne dla pacjentów, którzy mieli wcześniej poważne reakcje alergiczne na zimno, lub u których występuje ryzyko nagłej ekspozycji na zimno dotyczącej dużej powierzchni ciała (np. skoki do zimnej wody).495051

Dodatkowe strategie profilaktyczne

Desensytyzacja na zimno

Stopniowe budowanie tolerancji na zimno (desensytyzacja) może być skuteczną strategią profilaktyczną w niektórych przypadkach.5253

Proces polega na stopniowym przyzwyczajaniu skóry do zimnych warunków, a następnie regularnym poddawaniu jej działaniu zimna, na przykład poprzez regularne zimne prysznice. Należy jednak pamiętać, że tolerancja zazwyczaj utrzymuje się tylko przez kilka dni, a leczenie musi być regularnie powtarzane.5455

Metoda ta powinna być stosowana ostrożnie, pod nadzorem medycznym, aby uniknąć ryzyka wystąpienia poważnych reakcji.56

Edukacja pacjenta

Kluczowym elementem profilaktyki kurczowego zapalenia skóry na zimno jest właściwa edukacja pacjenta.57

Pacjenci powinni być świadomi:5859

  • Potencjalnego ryzyka anafilaksji, zwłaszcza przy zanurzeniu całego ciała w zimnej wodzie
  • Konieczności informowania personelu medycznego o swojej przypadłości przed każdym zabiegiem medycznym, stomatologicznym czy porodem
  • Technik unikania triggera i profilaktycznego stosowania leków
  • Konieczności prowadzenia dziennika objawów w celu identyfikacji osobistych czynników wyzwalających6061

Profilaktyka okołooperacyjna

Pacjenci z kurczowym zapaleniem skóry na zimno powinni zawsze informować chirurga i anestezjologa przed planowanym zabiegiem chirurgicznym. Pozwala to zespołowi operacyjnemu na podjęcie odpowiednich środków ostrożności, aby zapobiec wystąpieniu objawów w sali operacyjnej.6263

Zalecane środki ostrożności podczas zabiegu chirurgicznego obejmują:6465

  • Monitorowanie temperatury ciała pacjenta
  • Utrzymywanie jednolitej ciepłej temperatury w sali operacyjnej
  • Stosowanie koców grzewczych w razie potrzeby
  • Ogrzewanie płynów dożylnych przed podaniem
  • Przepisanie przedoperacyjnych leków przeciwhistaminowych nie wywołujących senności
  • Rozważenie zastosowania kortykosteroidów systemowych
  • Unikanie leków uwalniających histaminę, takich jak opioidy, oraz leków o wysokim ryzyku wywołania anafilaksji

Holistyczne podejście do profilaktyki

Oprócz typowych metod zapobiegania, warto uwzględnić kompleksowe podejście do profilaktyki kurczowego zapalenia skóry na zimno:6667

  • Dbanie o ogólny stan zdrowia – regularne ćwiczenia, zrównoważona dieta i odpowiednia ilość snu mogą wzmocnić układ odpornościowy i zmniejszyć prawdopodobieństwo wystąpienia zaostrzeń68
  • Techniki redukcji stresu – stres może nasilać objawy pokrzywki, dlatego włączenie aktywności redukujących stres, takich jak joga, medytacja i regularne ćwiczenia, może pomóc w zarządzaniu poziomem stresu i potencjalnie zmniejszyć częstotliwość zaostrzeń6970
  • Odpowiednie nawilżanie skóry – stosowanie delikatnych, bezzapachowych kosmetyków i kremów nawilżających może chronić skórę przed suchością i podrażnieniami, szczególnie w zimniejszych miesiącach7172
  • Unikanie innych potencjalnych czynników zaostrzających, takich jak aspiryna, alkohol i niesteroidowe leki przeciwzapalne73

Profilaktyka w szczególnych grupach pacjentów

Pacjenci z ryzykiem anafilaksji

Pacjenci z historią anafilaksji wywołanej zimnem wymagają szczególnej uwagi w zakresie profilaktyki. Badanie COLD-CE wykazało, że tylko niewielka część pacjentów z anafilaksją wywołaną zimnem otrzymała adrenalinę podczas epizodu anafilaksji lub miała przepisaną autostrzykawkę z adrenaliną.74

Dla tej grupy pacjentów zalecenia obejmują:7576

  • Przepisanie autostrzykawki z adrenaliną wszystkim pacjentom pediatrycznym z dodatnim testem na zimno
  • Rozszerzenie zalecenia posiadania autostrzykawki na wszystkich dorosłych pacjentów z dodatnim testem na zimno
  • Regularną kontrolę medyczną
  • Szczególną ostrożność podczas aktywności związanych z całkowitym zanurzeniem w wodzie
  • Rozważenie wcześniejszego zastosowania omalizumabu, nawet jeśli objawy są kontrolowane za pomocą leków przeciwhistaminowych H1 drugiej generacji

Pacjenci z zajściem błon śluzowych

U pacjentów, u których błony śluzowe reagują na zimno, spożywanie lodów lub zimnej wody może powodować obrzęk gardła, utrudniający oddychanie. Ta grupa pacjentów powinna:77

  • Bezwzględnie unikać zimnych pokarmów i napojów
  • Profilaktycznie stosować leki przeciwhistaminowe przed potencjalną ekspozycją
  • Mieć zawsze przy sobie autostrzykawkę z adrenaliną
  • Poinformować bliskie osoby o ryzyku i sposobie użycia autostrzykawki

Monitorowanie skuteczności profilaktyki

Ważnym elementem profilaktyki jest monitorowanie jej skuteczności i dostosowywanie strategii w zależności od odpowiedzi pacjenta.7879

Zaleca się:808182

  • Określenie wartości progowej temperatury wyzwalającej objawy, co pomaga w ocenie skuteczności leczenia
  • Prowadzenie dziennika objawów i ekspozycji na zimno, aby identyfikować czynniki wyzwalające i oceniać skuteczność stosowanych metod profilaktycznych
  • Regularne wizyty kontrolne u specjalisty (alergologa, immunologa lub dermatologa)
  • Stopniowe zmniejszanie leczenia po uzyskaniu odpowiedniej kontroli objawów

Podsumowanie zaleceń profilaktycznych

Profilaktyka kurczowego zapalenia skóry na zimno opiera się na kilku filarach:838485

  1. Unikanie ekspozycji na zimno – podstawowa metoda profilaktyczna
  2. Profilaktyczne stosowanie leków przeciwhistaminowych przed planowaną ekspozycją na zimno
  3. Rozważenie dodatkowych metod farmakologicznych w przypadku niewystarczającej kontroli objawów
  4. Posiadanie autostrzykawki z adrenaliną przez pacjentów z ryzykiem reakcji anafilaktycznej
  5. Edukacja pacjenta w zakresie rozpoznawania i unikania czynników wyzwalających
  6. Regularne wizyty kontrolne u specjalisty
  7. Informowanie personelu medycznego o schorzeniu przed zabiegami medycznymi

Chociaż nie istnieje lek całkowicie wyleczający kurczowe zapalenie skóry na zimno, odpowiednia profilaktyka i leczenie mogą znacząco poprawić jakość życia pacjentów i zapobiec poważnym reakcjom anafilaktycznym.868788

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  1. 11.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Diagnosis and management of cold urticaria – PubMed
    https://pubmed.ncbi.nlm.nih.gov/26919357/
    Cold urticaria is a physical urticaria characterized by a localized or systemic eruption of papules upon exposure of the skin to cold air, liquids, and/or objects. […] Avoidance of cold exposure is the most effective prophylactic measure. […] In mild to moderate cases, the primary goal of therapy is to improve the patient’s quality of life. […] In more severe cases, treatment measures to protect the patient’s airway, breathing, and circulation may be necessary.
  • #2 Cold urticaria – UpToDate
    https://www.uptodate.com/contents/cold-urticaria
    Cold urticaria is characterized by pruritic wheals (hives) and/or angioedema due to cutaneous mast cell degranulation and their release of proinflammatory mediators after cold exposure of the skin. […] Education about high-risk activities and cold avoidance is important in the management of cold urticaria. […] Preventative therapies include H1 antihistamines, which can be adjusted or discontinued based on the patient’s response. […] Cold desensitization may also be considered as part of the management strategy.
  • #3 Cold urticaria in tropics: A clinico-epidemiological study from North India – Indian Journal of Dermatology, Venereology and Leprology
    https://ijdvl.com/cold-urticaria-in-tropics-a-clinico-epidemiological-study-from-north-india/
    Cold urticaria (ColdU) is classified as a subtype of chronic inducible urticaria characterised by recurring pruritic wheals and/or angioedema upon exposure to cold stimuli. […] The management of ColdU involves a combination of protective measures against cold exposure and the use of anti-histamines to control disease activity. […] Management of ColdU involves measures to protect against cold exposure and the use of anti-histamines to alleviate symptoms. […] Patients received counselling on cold protection measures. […] In conclusion, this retrospective study sheds light on the clinical characteristics, epidemiology, and treatment response of North Indian patients with ColdU. Further research with larger and diverse populations, prospective, and exploration of genetic and environmental factors is needed to deepen our understanding of this condition in tropical regions.
  • #4 Cold Urticaria: What It Is, Symptoms, Causes & Treatment
    https://my.clevelandclinic.org/health/diseases/24629-cold-urticaria
    Because scientists dont fully understand the causes of urticaria, there arent any proven strategies to prevent it. […] If you have the condition, you can prevent reactions and episodes by avoiding cold temperatures, including cold food and drinks.
  • #5 Diagnosis and management of cold urticaria – PubMed
    https://pubmed.ncbi.nlm.nih.gov/26919357/
    Cold urticaria is a physical urticaria characterized by a localized or systemic eruption of papules upon exposure of the skin to cold air, liquids, and/or objects. […] Avoidance of cold exposure is the most effective prophylactic measure. […] In mild to moderate cases, the primary goal of therapy is to improve the patient’s quality of life. […] In more severe cases, treatment measures to protect the patient’s airway, breathing, and circulation may be necessary.
  • #6 Cold Allergy: Symptoms, Treatment, Prevention Tips, and More
    https://www.healthline.com/health/cold-allergy
    The best way to prevent cold urticaria and a possible allergic reaction to cold is to avoid exposure to cold temperatures. But this may not always be possible. […] Some ways to reduce your chance of developing symptoms include: […] Wear protective clothes during cold-weather months, like warm jackets, hats, gloves, and scarves. Try to expose as little skin as possible to cold temperatures. […] Test the temperature of water before submerging yourself in it and avoid frigid water. If you enjoy swimming in pools, look for a pool that is heated, even in warm weather. […] Bath and shower in warm water. […] Drink beverages that are room temperature and dont contain ice. […] Skip cold foods like ice cream and other frozen treats. […] Take a prescription medication, like an antihistamine, prior to being in the cold if your doctor recommends it.
  • #7 Cold Urticaria: What is it, Causes, Symptoms, and More
    https://www.webmd.com/skin-problems-and-treatments/what-is-cold-urticaria
    Tips to Manage and Prevent Cold Urticaria: There are a few tips and precautions you can take together with your medication to manage symptoms of cold urticaria. Try to avoid: Ice-cold drinks and frozen foods, Cold cosmetic procedures, Places with cooler temperatures like cellars and supermarkets with refrigerated shelves, Household tasks like defrosting the freezer or window cleaning, Outdoor activities like swimming, snowsports, and mountain climbing could trigger symptoms. […] Prevention tips include: Take prescribed or over-the-counter antihistamines before exposing yourself to the cold. If you have an epinephrine auto-injector, always have it on you in case a reaction occurs. Make sure you take all medication prescribed by your doctor. When you decide to go swimming, consider checking the water first with your hand to make sure it won’t cause a reaction. Always talk with your doctors about your condition before treatment or surgery to prevent medication or cold-induced urticaria symptoms. […] It’s important to note that if you have cold urticaria, you should always inform your doctor about your condition before getting any medical, dental, or childbirth procedures done. This will let them know to keep you warm while they do the procedure.
  • #8
    https://www.wyndly.com/blogs/learn/cold-urticaria?srsltid=AfmBOooH8XaOSXzRJP-CoE4QrAatjhMc-1ma6lo98S-vnCbwCvyAp4q3
    Cold urticaria treatment aims to manage symptoms and avoid triggers. Options include over-the-counter (OTC) medications, prescription drugs, and immunotherapy. A treatment plan is tailored to the individual’s specific needs. […] The first step in managing cold urticaria involves avoiding cold temperatures whenever possible. If exposure is unavoidable, protective clothing, warm beverages, and immediate warming after exposure can help. […] Preventing cold urticaria primarily involves avoiding exposure to cold temperatures. However, certain strategies can help manage the condition and reduce the frequency and severity of the symptoms. […] To start, it’s crucial to stay warm. Dress in layers and wear hats, scarves, and gloves when going out in cold weather. If you need to handle cold objects, use insulated gloves. Additionally, avoid consuming cold food and beverages as they can also trigger symptoms of cold urticaria.
  • #9 Cold Allergy: Symptoms, Treatment, Prevention Tips, and More
    https://www.healthline.com/health/cold-allergy
    The best way to prevent cold urticaria and a possible allergic reaction to cold is to avoid exposure to cold temperatures. But this may not always be possible. […] Some ways to reduce your chance of developing symptoms include: […] Wear protective clothes during cold-weather months, like warm jackets, hats, gloves, and scarves. Try to expose as little skin as possible to cold temperatures. […] Test the temperature of water before submerging yourself in it and avoid frigid water. If you enjoy swimming in pools, look for a pool that is heated, even in warm weather. […] Bath and shower in warm water. […] Drink beverages that are room temperature and dont contain ice. […] Skip cold foods like ice cream and other frozen treats. […] Take a prescription medication, like an antihistamine, prior to being in the cold if your doctor recommends it.
  • #10 How to Deal with Cold Urticaria: 7 Steps (with Pictures) – wikiHow
    https://www.wikihow.com/Deal-with-Cold-Urticaria
    Cold urticaria is an allergic skin reaction to cold temperatures. It can be triggered by exposure to cold weather, cold water, ice, and even cold food and beverages. The condition can usually be managed at home by avoiding cold temperatures, including cold food and beverages, although sometimes medical treatment is necessary. […] If you’ve noticed that your skin develops an itchy rash when it’s chilly, then the best precaution is to not expose yourself to cold weather conditions. This can be a challenge in northern climates, but making sure you’re always dressed warmly during winter months can help a great deal. […] Swimming in cold water is the most common cause or trigger of cold urticaria, particularly during windy conditions. […] Another activity that can trigger cold urticaria is holding and/or drinking cold beverages.
  • #11 Cold Urticaria – Global Allergy & Airways Patient PlatformExpandExpandExpandExpandExpandExpandToggle MenuScroll to topScroll to topExpandExpandExpandExpandExpandExpand
    https://gaapp.org/diseases/urticaria/forms-of-urticaria/cold-urticaria
    Most people rely on lifestyle changes to avoid flare-ups of their condition. However it doesn’t affect everyone in the same way. […] If you know you’re going to be unavoidably exposed to the cold, consider taking your antihistamine in advance. […] As well as taking your medication as prescribed, avoid or take precautions with: Visiting places with low ambient temperature e.g. cellars, ice rinks, supermarkets with refrigerated cabinets, etc. […] Before any medical or dental procedure or childbirth, tell your healthcare team that you have cold urticaria so they can keep you warm during the procedure.
  • #12 Cold Urticaria: What is it, Causes, Symptoms, and More
    https://www.webmd.com/skin-problems-and-treatments/what-is-cold-urticaria
    Tips to Manage and Prevent Cold Urticaria: There are a few tips and precautions you can take together with your medication to manage symptoms of cold urticaria. Try to avoid: Ice-cold drinks and frozen foods, Cold cosmetic procedures, Places with cooler temperatures like cellars and supermarkets with refrigerated shelves, Household tasks like defrosting the freezer or window cleaning, Outdoor activities like swimming, snowsports, and mountain climbing could trigger symptoms. […] Prevention tips include: Take prescribed or over-the-counter antihistamines before exposing yourself to the cold. If you have an epinephrine auto-injector, always have it on you in case a reaction occurs. Make sure you take all medication prescribed by your doctor. When you decide to go swimming, consider checking the water first with your hand to make sure it won’t cause a reaction. Always talk with your doctors about your condition before treatment or surgery to prevent medication or cold-induced urticaria symptoms. […] It’s important to note that if you have cold urticaria, you should always inform your doctor about your condition before getting any medical, dental, or childbirth procedures done. This will let them know to keep you warm while they do the procedure.
  • #13 Cold urticaria – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/cold-urticaria/symptoms-causes/syc-20371046
    Cold urticaria occurs most often in young adults. If you think you have this condition, check in with your healthcare team. Treatment usually includes steps to keep cold urticaria from happening, such as taking antihistamines and staying away from cold air and water. […] These tips may help stop cold urticaria from happening: Take an antihistamine available without a prescription as directed before being exposed to the cold. Protect your skin from the cold or sudden changes in temperature. If you’re going swimming, dip your hand in the water first to see if your skin responds. Stay away from ice-cold drinks and foods to keep your throat from swelling. If your healthcare professional prescribed an epinephrine autoinjector, keep it with you to help stop serious responses from happening. If you’re scheduled for surgery, talk with your surgeon ahead of time about your cold urticaria. The surgical team can take steps to help keep symptoms caused by cold from happening in the operating room.
  • #14 Cold urticaria // Middlesex Health
    https://middlesexhealth.org/learning-center/diseases-and-conditions/cold-urticaria
    Cold urticaria occurs most often in young adults. If you think you have this condition, check in with your healthcare team. Treatment usually includes steps to keep cold urticaria from happening, such as taking antihistamines and staying away from cold air and water. […] These tips may help stop cold urticaria from happening: Take an antihistamine available without a prescription as directed before being exposed to the cold. Protect your skin from the cold or sudden changes in temperature. If you’re going swimming, dip your hand in the water first to see if your skin responds. Stay away from ice-cold drinks and foods to keep your throat from swelling. If your healthcare professional prescribed an epinephrine autoinjector, keep it with you to help stop serious responses from happening. If you’re scheduled for surgery, talk with your surgeon ahead of time about your cold urticaria. The surgical team can take steps to help keep symptoms caused by cold from happening in the operating room.
  • #15 Cold Urticaria – Allergy & Asthma Network
    https://allergyasthmanetwork.org/chronic-urticaria/cold-urticaria/
    Cold urticaria is a chronic skin condition that occurs after sudden exposure to anything cold swimming in cold water, drinking a cold beverage, eating ice cream, handling a cold object, going for a walk in frigid temperatures, or even walking into an air-conditioned room. […] If you’re diagnosed with cold urticaria, here are some strategies to avoid a repeat episode: Take an over-the-counter antihistamine before exposure to cold to help reduce the risk of symptoms. […] Avoid drinking ice-cold beverages or eating frozen foods, such as ice cream. […] We learned that cold air could trigger a reaction. Living in the Midwest where long, harsh winters are common, we knew we’d need a well-thought-out plan for prevention. We invested in the warmest of outerwear and we carry epinephrine auto-injectors wherever we go in case she experiences a severe allergic reaction.
  • #16 Cold urticaria – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/cold-urticaria/symptoms-causes/syc-20371046
    Cold urticaria occurs most often in young adults. If you think you have this condition, check in with your healthcare team. Treatment usually includes steps to keep cold urticaria from happening, such as taking antihistamines and staying away from cold air and water. […] These tips may help stop cold urticaria from happening: Take an antihistamine available without a prescription as directed before being exposed to the cold. Protect your skin from the cold or sudden changes in temperature. If you’re going swimming, dip your hand in the water first to see if your skin responds. Stay away from ice-cold drinks and foods to keep your throat from swelling. If your healthcare professional prescribed an epinephrine autoinjector, keep it with you to help stop serious responses from happening. If you’re scheduled for surgery, talk with your surgeon ahead of time about your cold urticaria. The surgical team can take steps to help keep symptoms caused by cold from happening in the operating room.
  • #17 Cold Allergy: Symptoms, Treatment, Prevention Tips, and More
    https://www.healthline.com/health/cold-allergy
    The best way to prevent cold urticaria and a possible allergic reaction to cold is to avoid exposure to cold temperatures. But this may not always be possible. […] Some ways to reduce your chance of developing symptoms include: […] Wear protective clothes during cold-weather months, like warm jackets, hats, gloves, and scarves. Try to expose as little skin as possible to cold temperatures. […] Test the temperature of water before submerging yourself in it and avoid frigid water. If you enjoy swimming in pools, look for a pool that is heated, even in warm weather. […] Bath and shower in warm water. […] Drink beverages that are room temperature and dont contain ice. […] Skip cold foods like ice cream and other frozen treats. […] Take a prescription medication, like an antihistamine, prior to being in the cold if your doctor recommends it.
  • #18 Cold Urticaria: Symptoms, Causes, and Effective Home Remedies To Ease This Skin Condition
    https://www.netmeds.com/health-library/post/cold-urticaria-symptoms-causes-and-effective-home-remedies-to-ease-this-skin-condition?srsltid=AfmBOopC80XXnrFrwV7S9WCouJ1wJDZYDHstJ0iD1VU5lo1DPk0WRimG
    Cold urticaria occurs due to an overreaction of the skin’s immune system to cold stimuli. […] Reduce time spent in cold environments. […] Wear protective clothing, such as gloves and scarves, to safeguard the skin from cold air. […] Use lukewarm water instead of cold for bathing or washing hands. […] Over-the-counter antihistamine creams or oral antihistamines can help ease itching and swelling. […] Always consult a doctor before using them regularly. […] Apply a warm (not hot) compress to the affected regions to alleviate discomfort, soothe irritation and improve blood circulation. […] Use a gentle, fragrance-free moisturizer to shield the skin from dryness and irritation. […] Moisturize immediately after showering to lock in moisture. […] Consume a rich array of foods heaped with vitamin C, omega-3 fatty acids, and antioxidants, which help strengthen the immune system and reduce inflammation.
  • #19 Cold Urticaria: Symptoms, Causes, and Treatment
    https://resources.healthgrades.com/right-care/skin-hair-and-nails/cold-urticaria
    Cold urticaria is an allergic response that develops after exposure to the cold. It most often presents as a rash or hives. The main aim of cold urticaria treatment is to alleviate symptoms and prevent flare-ups. A key part of managing cold urticaria is learning and avoiding your personal triggers. To do this, you can start by recording your symptoms and note any activities that may have caused them. Once you have identified possible triggers, you can then take steps to avoid them or reduce their impact. For example, you may notice that quick rewarming after exposure to the cold triggers your cold urticaria. In this case, taking steps to warm up more gradually may help. This can include avoiding washing your hands or bathing with warm water immediately after cold exposure and avoiding sitting next to radiators when coming inside from cold weather. If avoiding your triggers is difficult, medical therapies may also help. These can include over-the-counter antihistamine medication, taken before exposure, prescription medications, such as omalizumab (Xolair), and epinephrine pens (Epi-Pen, Adrenaclick, Twinject), in case of severe allergic reactions or anaphylaxis. Your doctor may prescribe an epinephrine pen and recommend carrying it with you at all times. Epinephrine can help stop anaphylaxis and reduce your symptoms. […] Treatments for cold urticaria include identifying and avoiding possible triggers and taking antihistamine medications.
  • #20 Cold Urticaria: What is it, Causes, Symptoms, and More
    https://www.webmd.com/skin-problems-and-treatments/what-is-cold-urticaria
    Tips to Manage and Prevent Cold Urticaria: There are a few tips and precautions you can take together with your medication to manage symptoms of cold urticaria. Try to avoid: Ice-cold drinks and frozen foods, Cold cosmetic procedures, Places with cooler temperatures like cellars and supermarkets with refrigerated shelves, Household tasks like defrosting the freezer or window cleaning, Outdoor activities like swimming, snowsports, and mountain climbing could trigger symptoms. […] Prevention tips include: Take prescribed or over-the-counter antihistamines before exposing yourself to the cold. If you have an epinephrine auto-injector, always have it on you in case a reaction occurs. Make sure you take all medication prescribed by your doctor. When you decide to go swimming, consider checking the water first with your hand to make sure it won’t cause a reaction. Always talk with your doctors about your condition before treatment or surgery to prevent medication or cold-induced urticaria symptoms. […] It’s important to note that if you have cold urticaria, you should always inform your doctor about your condition before getting any medical, dental, or childbirth procedures done. This will let them know to keep you warm while they do the procedure.
  • #21 Clinical characteristics of cold-induced systemic reactions in acquired cold urticaria syndromes: recommendations for prevention of this complication and a proposal for a diagnostic classification of cold urticaria – PubMed
    https://pubmed.ncbi.nlm.nih.gov/3760401/
    The acquired cold urticaria (ACU) syndromes consists of nonfamilial heterogeneous disorders characterized by urticaria, angioedema, and occasionally symptoms of hypotension after cold exposure. […] These observations indicate that all patients with ACU with active histories of cold urticaria are at risk to develop systemic reactions to cold and should therefore refrain from participating in aquatic activities. […] In addition, high-risk patients should receive prophylactic medications (i.e., cyproheptadine or doxepin) that are effective in suppressing this disorder.
  • #22
    https://www.healio.com/news/allergy-asthma/20210809/omalizumab-effectively-treats-chronic-cold-urticaria
    Omalizumab effectively treated chronic cold urticaria and prevented further episodes of anaphylaxis, according to a single-center study published in The Journal of Allergy and Clinical Immunology: In Practice. […] However, in CCU, there is a risk for life-threatening anaphylaxis upon sudden exposure to cold in a large body surface area, Hartog said. One such situation could include jumping into a cold body of water. Because of this risk, we do counsel patients about the risk for anaphylaxis and prescribe an epinephrine autoinjector. […] Currently, the researchers said, there are no clear guidelines for specifically treating CCU or if it should be treated differently from chronic spontaneous urticaria, although second-generation nonsedating H1-antihistamines often are used as the first line of treatment.
  • #23 Cold urticaria
    https://dermnetnz.org/topics/cold-urticaria
    Cold urticaria can be diagnosed by applying an ice cube against the skin of the forearm for 15 minutes. A distinct red swollen rash should develop within minutes in the area exposed to the cold-stimulation test if a patient has cold urticaria. […] Patients with cold urticaria should learn to protect themselves from a rapid drop in body temperature. Aquatic activities (such as swimming and surfing) should always be under supervision. […] Cautious induction of cold tolerance may be successful (desensitisation), by gradually hardening the skin to cold conditions and then exposing the skin to it regularly, for example, by taking regular cold showers. […] The anaesthetist should be told in advance that the patient has cold urticaria. Staff must take precautions to keep the patient warm.
  • #24 Hives (Urticaria): Causes, Symptoms, and Treatment
    https://patient.info/skin-conditions/hives-inducible-urticaria
    Cold hives are quite an uncommon condition. An urticarial rash develops after being exposed to cold, including rain, cold winds and cold water. It may be the cold that triggers the rash, or the re-warming of the skin after coming in from the cold. […] If a large area of skin has been chilled, the rash can be very extensive. For example, swimming in cold water may cause a widespread and severe rash over most of the body that can cause dizziness or fainting. (For this reason, people who are known to develop cold hives should never go swimming alone.) […] Once it is clear what causes the hives, it may be possible to avoid situations that trigger them. For example, dermographism can often be prevented by avoiding firm pressure against the skin as much as possible. In mild cases, no additional treatment may be needed. […] In cholinergic urticaria where the rash develops on exercise, a dose of an antihistamine just before exercising may help to prevent or limit a flare-up of the rash.
  • #25 Cold Urticaria: What is it, Causes, Symptoms, and More
    https://www.webmd.com/skin-problems-and-treatments/what-is-cold-urticaria
    Tips to Manage and Prevent Cold Urticaria: There are a few tips and precautions you can take together with your medication to manage symptoms of cold urticaria. Try to avoid: Ice-cold drinks and frozen foods, Cold cosmetic procedures, Places with cooler temperatures like cellars and supermarkets with refrigerated shelves, Household tasks like defrosting the freezer or window cleaning, Outdoor activities like swimming, snowsports, and mountain climbing could trigger symptoms. […] Prevention tips include: Take prescribed or over-the-counter antihistamines before exposing yourself to the cold. If you have an epinephrine auto-injector, always have it on you in case a reaction occurs. Make sure you take all medication prescribed by your doctor. When you decide to go swimming, consider checking the water first with your hand to make sure it won’t cause a reaction. Always talk with your doctors about your condition before treatment or surgery to prevent medication or cold-induced urticaria symptoms. […] It’s important to note that if you have cold urticaria, you should always inform your doctor about your condition before getting any medical, dental, or childbirth procedures done. This will let them know to keep you warm while they do the procedure.
  • #26
    https://www.wyndly.com/blogs/learn/cold-urticaria?srsltid=AfmBOooH8XaOSXzRJP-CoE4QrAatjhMc-1ma6lo98S-vnCbwCvyAp4q3
    Next, plan ahead. Always check the weather forecast before leaving the house and prepare accordingly. If you anticipate being in cold environments, bring along hot drinks, heating pads, or warm blankets to help maintain your body temperature. […] Finally, take care of your overall health. Regular exercise, a balanced diet, and adequate sleep can help strengthen your immune system and decrease the likelihood of allergy hives flare-ups. […] Remember, these strategies are not a substitute for medical advice. Always consult a healthcare professional to develop a comprehensive management plan for cold urticaria.
  • #27 Cold urticaria – Diagnosis & treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/cold-urticaria/diagnosis-treatment/drc-20371051
    In some people, cold urticaria goes away on its own after weeks or months. In others, it lasts longer. While there is no cure for the condition, treatment and taking steps to avoid cold urticaria can help. […] Your healthcare professional may recommend that you try to keep symptoms from happening or reduce those symptoms using home remedies. These remedies include antihistamines available without a prescription and staying away from the cold. If these treatments don’t help, you may need prescription medicine. […] If you know you’re going to be exposed to the cold, take an antihistamine ahead of time to help keep a response from happening. […] Antihistamines block the release of histamine that causes symptoms. These medicines can be used to treat mild symptoms of cold urticaria or to keep a response from happening. Medicines available without a prescription include forms of loratadine and cetirizine.
  • #28 Welts on skin due to cold temperature could be hives
    https://www.aad.org/public/diseases/a-z/hives-cold-urticaria
    If you get hives from the cold, it doesn’t mean you have to live with flare-ups. Taking some precautions may help you avoid hives. Medication may also prevent hives. […] When possible, treatment begins with avoiding what causes your hives. For example, if cold water causes hives, you’ll want to avoid it. If your throat swells when you eat or drink anything cold, you should avoid all cold foods and drinks. […] If you cannot avoid what causes your hives, medication can help. Medication can be helpful for someone who cannot go outdoors in the winter without getting hives. It can prevent hives if your child wants to swim in a pool with friends during the summer. […] One medication that helps many people who have cold urticaria is an oral antihistamine. It can prevent hives from developing. An oral antihistamine can also prevent symptoms like itchiness. […] If oral antihistamines fail to prevent hives, your dermatologist may prescribe a stronger medication or add another medication to your treatment plan.
  • #29 Cold urticaria – Diagnosis & treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/cold-urticaria/diagnosis-treatment/drc-20371051
    In some people, cold urticaria goes away on its own after weeks or months. In others, it lasts longer. While there is no cure for the condition, treatment and taking steps to avoid cold urticaria can help. […] Your healthcare professional may recommend that you try to keep symptoms from happening or reduce those symptoms using home remedies. These remedies include antihistamines available without a prescription and staying away from the cold. If these treatments don’t help, you may need prescription medicine. […] If you know you’re going to be exposed to the cold, take an antihistamine ahead of time to help keep a response from happening. […] Antihistamines block the release of histamine that causes symptoms. These medicines can be used to treat mild symptoms of cold urticaria or to keep a response from happening. Medicines available without a prescription include forms of loratadine and cetirizine.
  • #30 Cold Hives (urticaria): A review – Los Angeles Allergist
    https://allergylosangeles.com/allergy-blog/cold-hives-urticaria-a-review/
    Cold exposure can also lead to a potentially serious and fatal reaction in specific circumstances (jumping into a cold body of water) can lead to anaphylaxis. Some patients may need to carry an injectable epinephrine for those at risk. […] Besides avoiding the cold, other treatments are available. Non sedating second generation antihistamines and Xolair (omalizumab) are being used to treat cold hives. […] Antihistamines such as Clarinex (desloratadine), Xyzal (levocetirizine), Zyrtec (cetirizine), Allegra (fexofenadine), are just some of the few that are used to treat and prevent hives in patients with cold urticaria. […] The biggest takeaway for the treatment of cold hives is that non-sedating antihistamines are effective in the treatment of cold hives in higher than standard doses (up to 4-fold), and updosing does not increase side effects. For treatment resistant patients, Xolair monthly is also effective, although this is an off-label use.
  • #31 Review of cold-induced urticaria characteristics, diagnosis and management in a Western Canadian allergy practice | Allergy, Asthma & Clinical Immunology | Full Text
    https://aacijournal.biomedcentral.com/articles/10.1186/s13223-018-0310-5
    Cold-induced urticaria is divided into primary and secondary forms and there have been many associations reported in the literature. […] Diagnosis is made through provocation tests including either the ice cube test or TempTest measurements, both of which were listed as acceptable in recent guidelines outlined by the 2016 EAACI/GA2LEN/EDFUNEV. Treatment is largely symptomatic and consists of cold avoidance and medical management with antihistamines. For those resistant to antihistamines, omalizumab is recommended and has worked well in some trials. […] Avoidance of cold, such as immersion into cold bodies of water, is often recommended for both treatment and avoidance of a potentially more systemic reaction such as anaphylaxis. However, this advice is often not achievable or fully effective in managing symptoms. Non-sedating antihistamines, used up to four times the standard dose for those that do not respond to the standard dose, has been shown in multiple clinical trials to be effective in controlling the frequency and severity of symptoms associated with cold-induced urticaria, regardless of the etiology. […] For patients with refractory symptoms on maximal treatment with antihistamines, treatment with omalizumab or cyclosporine is recommended.
  • #32 Cold Hives (urticaria): A review – Los Angeles Allergist
    https://allergylosangeles.com/allergy-blog/cold-hives-urticaria-a-review/
    Cold exposure can also lead to a potentially serious and fatal reaction in specific circumstances (jumping into a cold body of water) can lead to anaphylaxis. Some patients may need to carry an injectable epinephrine for those at risk. […] Besides avoiding the cold, other treatments are available. Non sedating second generation antihistamines and Xolair (omalizumab) are being used to treat cold hives. […] Antihistamines such as Clarinex (desloratadine), Xyzal (levocetirizine), Zyrtec (cetirizine), Allegra (fexofenadine), are just some of the few that are used to treat and prevent hives in patients with cold urticaria. […] The biggest takeaway for the treatment of cold hives is that non-sedating antihistamines are effective in the treatment of cold hives in higher than standard doses (up to 4-fold), and updosing does not increase side effects. For treatment resistant patients, Xolair monthly is also effective, although this is an off-label use.
  • #33 Acute and Chronic Urticaria: Evaluation and Treatment | AAFP
    https://www.aafp.org/pubs/afp/issues/2017/0601/p717.html
    Urticaria is a common dermatologic condition that typically presents with intensely pruritic, well-circumscribed, raised wheals ranging from several millimeters to several centimeters or larger in size. […] The mainstay of treatment is avoidance of triggers, if identified. […] Methods of treatment for urticaria are the same for adults and children. The mainstay of treatment is avoidance of identified triggers. It is also recommended that patients avoid using aspirin, alcohol, and NSAIDs, as well as avoid wearing tight clothing, because these may worsen symptoms. […] If trigger avoidance is impossible, no trigger is identified, or symptom relief is needed despite trigger avoidance, H1-antihistamines are first-line pharmacotherapy. […] For improved symptom control, the medication should be dosed daily, rather than on an as-needed basis.
  • #34 Acute and Chronic Urticaria: Evaluation and Treatment | AAFP
    https://www.aafp.org/pubs/afp/issues/2017/0601/p717.html
    Urticaria is a common dermatologic condition that typically presents with intensely pruritic, well-circumscribed, raised wheals ranging from several millimeters to several centimeters or larger in size. […] The mainstay of treatment is avoidance of triggers, if identified. […] Methods of treatment for urticaria are the same for adults and children. The mainstay of treatment is avoidance of identified triggers. It is also recommended that patients avoid using aspirin, alcohol, and NSAIDs, as well as avoid wearing tight clothing, because these may worsen symptoms. […] If trigger avoidance is impossible, no trigger is identified, or symptom relief is needed despite trigger avoidance, H1-antihistamines are first-line pharmacotherapy. […] For improved symptom control, the medication should be dosed daily, rather than on an as-needed basis.
  • #35 10 ways to get relief from chronic hives
    https://www.aad.org/public/diseases/a-z/hives-chronic-relief
    Hives or an itchy rash can appear when you start to warm up after being in cold water or outdoors in the cold. Hives can also appear almost immediately when you go into an air-conditioned building or walk near a freezer case. […] Avoid overheating. […] Apply a cool compress (unless cold triggers your hives). To make a cold compress, you can apply a clean, cool and damp washcloth or a clean washcloth in which ice cubes are wrapped. Place the cool compress on your itchy skin several times a day. […] Treatment may fail to work when you take medication less often than prescribed. For example, if your dermatologist prescribes a daily oral antihistamine and you only take it when you have a flare-up, you may continue to get hives. […] Understand that extensive allergy testing often does not find a specific cause or allergen. Many people believe that their hives would go away if they could just find out what’s causing the flare-ups. Even when the cause remains unknown, treatment can clear your skin and keep it clear.
  • #36 Acute and Chronic Urticaria: Evaluation and Treatment | AAFP
    https://www.aafp.org/pubs/afp/issues/2017/0601/p717.html
    If symptomatic control is still not achieved, the third step is addition and titration of high-potency antihistamines as tolerated, such as hydroxyzine or the tricyclic antidepressant doxepin (possesses markedly more antihistaminic effect than diphenhydramine). […] Once symptoms are adequately controlled, physicians should consider stepping down treatment sequentially. […] If an underlying cause of chronic urticaria is identified, the condition should be treated or the patient referred to an appropriate subspecialist.
  • #37 Review of cold-induced urticaria characteristics, diagnosis and management in a Western Canadian allergy practice | Allergy, Asthma & Clinical Immunology | Full Text
    https://aacijournal.biomedcentral.com/articles/10.1186/s13223-018-0310-5
    Cold-induced urticaria is divided into primary and secondary forms and there have been many associations reported in the literature. […] Diagnosis is made through provocation tests including either the ice cube test or TempTest measurements, both of which were listed as acceptable in recent guidelines outlined by the 2016 EAACI/GA2LEN/EDFUNEV. Treatment is largely symptomatic and consists of cold avoidance and medical management with antihistamines. For those resistant to antihistamines, omalizumab is recommended and has worked well in some trials. […] Avoidance of cold, such as immersion into cold bodies of water, is often recommended for both treatment and avoidance of a potentially more systemic reaction such as anaphylaxis. However, this advice is often not achievable or fully effective in managing symptoms. Non-sedating antihistamines, used up to four times the standard dose for those that do not respond to the standard dose, has been shown in multiple clinical trials to be effective in controlling the frequency and severity of symptoms associated with cold-induced urticaria, regardless of the etiology. […] For patients with refractory symptoms on maximal treatment with antihistamines, treatment with omalizumab or cyclosporine is recommended.
  • #38
    https://www.healio.com/news/allergy-asthma/20210809/omalizumab-effectively-treats-chronic-cold-urticaria
    Overall, four of the six patients who had a history of anaphylaxis had no further anaphylactic episodes with omalizumab. […] The researchers noted questions remain regarding the proper time for initiating omalizumab, the adequate treatment duration and dosage, and use of alternative immunomodulatory therapies. […] He also said three key unresolved questions remain, including defining the ideal treatment algorithm; whether omalizumab affects the rate of cold-induced anaphylaxis or, rather, whether controlling the CCU decreases its rate; and if a history of cold-induced anaphylaxis should prompt clinicians to consider omalizumab earlier, even if symptoms are controlled with a second-generation H1-antihistamine.
  • #39 Cold urticaria prevalence, treatments, and risk of anaphylaxis
    https://www.aaaai.org/tools-for-the-public/latest-research-summaries/the-journal-of-allergy-and-clinical-immunology-in/2021/cold-urticaria
    Cold urticaria is a subtype of chronic urticaria and is a rare skin disease involving hives, itching, or swelling triggered by cold water, food, or objects. […] The most common treatments for cold urticaria were second generation H1-antihistamines in 95.67% of patients, followed by omalizumab in 5.95% of patients. […] Given that anaphylaxis is not rare in patients with cold urticaria, prescribing epinephrine autoinjectors should be considered.
  • #40 Acute and Chronic Urticaria: Evaluation and Treatment | AAFP
    https://www.aafp.org/pubs/afp/issues/2017/0601/p717.html
    If symptomatic control is still not achieved, the third step is addition and titration of high-potency antihistamines as tolerated, such as hydroxyzine or the tricyclic antidepressant doxepin (possesses markedly more antihistaminic effect than diphenhydramine). […] Once symptoms are adequately controlled, physicians should consider stepping down treatment sequentially. […] If an underlying cause of chronic urticaria is identified, the condition should be treated or the patient referred to an appropriate subspecialist.
  • #41 Acute and Chronic Urticaria: Evaluation and Treatment | AAFP
    https://www.aafp.org/pubs/afp/issues/2017/0601/p717.html
    If symptomatic control is still not achieved, the third step is addition and titration of high-potency antihistamines as tolerated, such as hydroxyzine or the tricyclic antidepressant doxepin (possesses markedly more antihistaminic effect than diphenhydramine). […] Once symptoms are adequately controlled, physicians should consider stepping down treatment sequentially. […] If an underlying cause of chronic urticaria is identified, the condition should be treated or the patient referred to an appropriate subspecialist.
  • #42 Clinical characteristics of cold-induced systemic reactions in acquired cold urticaria syndromes: recommendations for prevention of this complication and a proposal for a diagnostic classification of cold urticaria – PubMed
    https://pubmed.ncbi.nlm.nih.gov/3760401/
    The acquired cold urticaria (ACU) syndromes consists of nonfamilial heterogeneous disorders characterized by urticaria, angioedema, and occasionally symptoms of hypotension after cold exposure. […] These observations indicate that all patients with ACU with active histories of cold urticaria are at risk to develop systemic reactions to cold and should therefore refrain from participating in aquatic activities. […] In addition, high-risk patients should receive prophylactic medications (i.e., cyproheptadine or doxepin) that are effective in suppressing this disorder.
  • #43 Hives – Wikipedia
    https://en.wikipedia.org/wiki/Hives
    Prevention is by avoiding whatever it is that causes the condition. […] Keeping the environmental temperature cool is also useful. […] People with cold urticaria need to learn to protect themselves from a hasty drop in body temperature. Regular antihistamines are not generally efficacious. One particular antihistamine, cyproheptadine (Periactin), has been found to be useful. […] Finally, a medication named ketotifen, which keeps mast cells from discharging histamine, has also been employed with widespread success.
  • #44 Hives – Wikipedia
    https://en.wikipedia.org/wiki/Hives
    Prevention is by avoiding whatever it is that causes the condition. […] Keeping the environmental temperature cool is also useful. […] People with cold urticaria need to learn to protect themselves from a hasty drop in body temperature. Regular antihistamines are not generally efficacious. One particular antihistamine, cyproheptadine (Periactin), has been found to be useful. […] Finally, a medication named ketotifen, which keeps mast cells from discharging histamine, has also been employed with widespread success.
  • #45 Diagnosis and Management of Cold Urticaria | MDedge
    https://www.mdedge.com/cutis/article/105720/urticaria/diagnosis-and-management-cold-urticaria
    Cold urticaria is a physical urticaria characterized by a localized or systemic eruption of papules upon exposure of the skin to cold air, liquids, and/or objects. […] Avoidance of cold exposure is the most effective prophylactic measure. […] Pharmacologic therapies with prophylactic effects that may reduce the intensity of symptoms or inhibit their development include antihistamines, leuko-triene receptor antagonists, biologics, and glucocorticoids. […] He eventually decided to treat his symptoms with lifestyle choices only, such as making sure to be well covered in cold temperatures.
  • #46 Cold Urticaria – Allergy & Asthma Network
    https://allergyasthmanetwork.org/chronic-urticaria/cold-urticaria/
    Cold urticaria is a chronic skin condition that occurs after sudden exposure to anything cold swimming in cold water, drinking a cold beverage, eating ice cream, handling a cold object, going for a walk in frigid temperatures, or even walking into an air-conditioned room. […] If you’re diagnosed with cold urticaria, here are some strategies to avoid a repeat episode: Take an over-the-counter antihistamine before exposure to cold to help reduce the risk of symptoms. […] Avoid drinking ice-cold beverages or eating frozen foods, such as ice cream. […] We learned that cold air could trigger a reaction. Living in the Midwest where long, harsh winters are common, we knew we’d need a well-thought-out plan for prevention. We invested in the warmest of outerwear and we carry epinephrine auto-injectors wherever we go in case she experiences a severe allergic reaction.
  • #47
    https://www.healio.com/news/allergy-asthma/20210809/omalizumab-effectively-treats-chronic-cold-urticaria
    Omalizumab effectively treated chronic cold urticaria and prevented further episodes of anaphylaxis, according to a single-center study published in The Journal of Allergy and Clinical Immunology: In Practice. […] However, in CCU, there is a risk for life-threatening anaphylaxis upon sudden exposure to cold in a large body surface area, Hartog said. One such situation could include jumping into a cold body of water. Because of this risk, we do counsel patients about the risk for anaphylaxis and prescribe an epinephrine autoinjector. […] Currently, the researchers said, there are no clear guidelines for specifically treating CCU or if it should be treated differently from chronic spontaneous urticaria, although second-generation nonsedating H1-antihistamines often are used as the first line of treatment.
  • #48
    https://link.springer.com/article/10.1007/s40521-024-00366-9
    ColdA is a major and potentially life-threatening concern for a subset of ColdU patients. Early recognition of high-risk patients, coupled with education and preparedness of both patients and healthcare providers, is crucial for effectively managing this challenging condition. […] Patients at high risk for anaphylaxis require provision of AAIs. The COLD-CE study highlighted that only a minority of ColdA patients received adrenaline during their anaphylaxis episode or were prescribed an AAI. Recommendations for prescribing AAIs vary: Yee et al. and Alangari et al. advised that all pediatric patients with ColdUT should have AAIs, while Katsarou-Katsari et al. extended this recommendation to all adult patients with ColdUT. […] Patients at high risk of ColdA require not only comprehensive education but also regular medical follow-ups. Education is crucial, as patients who are unaware of their condition’s risks are more vulnerable to life-threatening complications. Key educational points include: Trigger avoidance: Patients must be advised to exercise caution during activities involving complete water immersion, such as swimming in the sea, lake or pool.
  • #49 Cold Urticaria: Symptoms, Causes, and Treatment
    https://resources.healthgrades.com/right-care/skin-hair-and-nails/cold-urticaria
    Cold urticaria is an allergic response that develops after exposure to the cold. It most often presents as a rash or hives. The main aim of cold urticaria treatment is to alleviate symptoms and prevent flare-ups. A key part of managing cold urticaria is learning and avoiding your personal triggers. To do this, you can start by recording your symptoms and note any activities that may have caused them. Once you have identified possible triggers, you can then take steps to avoid them or reduce their impact. For example, you may notice that quick rewarming after exposure to the cold triggers your cold urticaria. In this case, taking steps to warm up more gradually may help. This can include avoiding washing your hands or bathing with warm water immediately after cold exposure and avoiding sitting next to radiators when coming inside from cold weather. If avoiding your triggers is difficult, medical therapies may also help. These can include over-the-counter antihistamine medication, taken before exposure, prescription medications, such as omalizumab (Xolair), and epinephrine pens (Epi-Pen, Adrenaclick, Twinject), in case of severe allergic reactions or anaphylaxis. Your doctor may prescribe an epinephrine pen and recommend carrying it with you at all times. Epinephrine can help stop anaphylaxis and reduce your symptoms. […] Treatments for cold urticaria include identifying and avoiding possible triggers and taking antihistamine medications.
  • #50 Cold hives: Symptoms, causes, and treatment
    https://www.medicalnewstoday.com/articles/cold-hives
    Epinephrine: For people who have previously had serious allergic reactions to the cold, it may be necessary to carry an epinephrine pen in case this happens again. This emergency medication can stop anaphylaxis. […] It is important to avoid any topical products or treatments that cool the skin. People should tell medical or cosmetic professionals about having cold hives before undergoing any procedures.
  • #51 Cold urticaria prevalence, treatments, and risk of anaphylaxis
    https://www.aaaai.org/tools-for-the-public/latest-research-summaries/the-journal-of-allergy-and-clinical-immunology-in/2021/cold-urticaria
    Cold urticaria is a subtype of chronic urticaria and is a rare skin disease involving hives, itching, or swelling triggered by cold water, food, or objects. […] The most common treatments for cold urticaria were second generation H1-antihistamines in 95.67% of patients, followed by omalizumab in 5.95% of patients. […] Given that anaphylaxis is not rare in patients with cold urticaria, prescribing epinephrine autoinjectors should be considered.
  • #52 Cold urticaria
    https://dermnetnz.org/topics/cold-urticaria
    Cold urticaria can be diagnosed by applying an ice cube against the skin of the forearm for 15 minutes. A distinct red swollen rash should develop within minutes in the area exposed to the cold-stimulation test if a patient has cold urticaria. […] Patients with cold urticaria should learn to protect themselves from a rapid drop in body temperature. Aquatic activities (such as swimming and surfing) should always be under supervision. […] Cautious induction of cold tolerance may be successful (desensitisation), by gradually hardening the skin to cold conditions and then exposing the skin to it regularly, for example, by taking regular cold showers. […] The anaesthetist should be told in advance that the patient has cold urticaria. Staff must take precautions to keep the patient warm.
  • #53 Cold urticaria – UpToDate
    https://www.uptodate.com/contents/cold-urticaria
    Cold urticaria is characterized by pruritic wheals (hives) and/or angioedema due to cutaneous mast cell degranulation and their release of proinflammatory mediators after cold exposure of the skin. […] Education about high-risk activities and cold avoidance is important in the management of cold urticaria. […] Preventative therapies include H1 antihistamines, which can be adjusted or discontinued based on the patient’s response. […] Cold desensitization may also be considered as part of the management strategy.
  • #54 Cold urticaria
    https://dermnetnz.org/topics/cold-urticaria
    Cold urticaria can be diagnosed by applying an ice cube against the skin of the forearm for 15 minutes. A distinct red swollen rash should develop within minutes in the area exposed to the cold-stimulation test if a patient has cold urticaria. […] Patients with cold urticaria should learn to protect themselves from a rapid drop in body temperature. Aquatic activities (such as swimming and surfing) should always be under supervision. […] Cautious induction of cold tolerance may be successful (desensitisation), by gradually hardening the skin to cold conditions and then exposing the skin to it regularly, for example, by taking regular cold showers. […] The anaesthetist should be told in advance that the patient has cold urticaria. Staff must take precautions to keep the patient warm.
  • #55 aha! Swiss Allergy Centre – Urticaria (hives/nettle rash)
    https://www.aha.ch/swiss-allergy-centre/skin/urticaria-hives-nettle-rash
    Cold urticaria (cold contact urticaria): Wheals or angioedema form within minutes when the skin comes into contact with cold cold air/wind, liquids or solid objects and is then exposed to heat. The symptoms normally persist for an hour or so. In severe cases, it may result in general reactions up to and including anaphylactic shock. […] The development of tolerance can be successful in treating certain forms of chronic inducible urticaria (cold urticaria, light urticaria and cholinergic urticaria). However, this tolerance usually only lasts for a few days and the treatment such as a cold shower every day for cold urticaria must be repeated regularly. Sufferers often find this excessive and/or unpleasant.
  • #56 Understanding Cold and Heat-Induced Urticaria: Causes, Symptoms, and Management
    https://www.mamahealth.com/chronic-spontaneous-urticaria/cold-and-heat-induced
    Cold-induced urticaria (also called cold urticaria) is triggered by exposure to cold temperatures, such as cold air, water, or objects. When the skin is exposed to cold, histamine and other chemicals are released, causing hives to form. […] The first step in managing temperature-induced urticaria is to avoid known triggers. This may involve making lifestyle adjustments to minimize exposure to cold or heat. […] For Cold Urticaria: Dress Warmly: Wear appropriate clothing to protect skin from cold weather. Avoid Cold Water: Refrain from swimming in cold water and use lukewarm water for bathing. Use Insulated Gloves: Handle cold objects with insulated gloves to protect your skin. […] In some cases, gradual desensitization to cold or heat can help reduce sensitivity. This involves controlled exposure to the triggering temperature in a safe and monitored environment, allowing the body to build tolerance over time. […] Stress can exacerbate urticaria symptoms. Incorporating stress-reducing activities, such as yoga, meditation, and regular exercise, can help manage stress levels and potentially reduce the frequency of flare-ups.
  • #57
    https://link.springer.com/article/10.1007/s40521-024-00366-9
    ColdA is a major and potentially life-threatening concern for a subset of ColdU patients. Early recognition of high-risk patients, coupled with education and preparedness of both patients and healthcare providers, is crucial for effectively managing this challenging condition. […] Patients at high risk for anaphylaxis require provision of AAIs. The COLD-CE study highlighted that only a minority of ColdA patients received adrenaline during their anaphylaxis episode or were prescribed an AAI. Recommendations for prescribing AAIs vary: Yee et al. and Alangari et al. advised that all pediatric patients with ColdUT should have AAIs, while Katsarou-Katsari et al. extended this recommendation to all adult patients with ColdUT. […] Patients at high risk of ColdA require not only comprehensive education but also regular medical follow-ups. Education is crucial, as patients who are unaware of their condition’s risks are more vulnerable to life-threatening complications. Key educational points include: Trigger avoidance: Patients must be advised to exercise caution during activities involving complete water immersion, such as swimming in the sea, lake or pool.
  • #58 Cold urticaria – ECARF
    https://www.ecarf.org/en/coldurticaria/
    Cold urticaria can become dangerous in rare cases, such as when hives appear all over the body after jumping into cold water. Magerl says that hives covering such a large area can be hard on the circulation. Significant amounts of fluids can seep from the blood into the skin. This can lead to a drop in blood pressure and eventually shock and loss of consciousness. Patients should be made aware of this possibility. Urticaria can also cause difficulties for people whose mucous membranes react to the cold. Whenever these patients eat ice cream or drink cold water, swelling can occur in the throat, making it difficult to breathe. […] Various medications are available for the treatment of cold urticaria. The hives can be prevented by avoiding cold stimuli by wearing warm clothing or using face cream, for example. But this is not always practical, so antihistamines are the next best option. Although they cannot cure the disease, they can reduce the symptoms. If they are not effective, the doctor can increase the dosage by four. […] The allergologist also points out that it is useful to pinpoint the threshold value in order to determine whether a certain type of treatment is working.
  • #59
    https://link.springer.com/article/10.1007/s40521-024-00366-9
    ColdA is a major and potentially life-threatening concern for a subset of ColdU patients. Early recognition of high-risk patients, coupled with education and preparedness of both patients and healthcare providers, is crucial for effectively managing this challenging condition. […] Patients at high risk for anaphylaxis require provision of AAIs. The COLD-CE study highlighted that only a minority of ColdA patients received adrenaline during their anaphylaxis episode or were prescribed an AAI. Recommendations for prescribing AAIs vary: Yee et al. and Alangari et al. advised that all pediatric patients with ColdUT should have AAIs, while Katsarou-Katsari et al. extended this recommendation to all adult patients with ColdUT. […] Patients at high risk of ColdA require not only comprehensive education but also regular medical follow-ups. Education is crucial, as patients who are unaware of their condition’s risks are more vulnerable to life-threatening complications. Key educational points include: Trigger avoidance: Patients must be advised to exercise caution during activities involving complete water immersion, such as swimming in the sea, lake or pool.
  • #60 Cold Urticaria: Symptoms, Causes, and Treatment
    https://resources.healthgrades.com/right-care/skin-hair-and-nails/cold-urticaria
    Cold urticaria is an allergic response that develops after exposure to the cold. It most often presents as a rash or hives. The main aim of cold urticaria treatment is to alleviate symptoms and prevent flare-ups. A key part of managing cold urticaria is learning and avoiding your personal triggers. To do this, you can start by recording your symptoms and note any activities that may have caused them. Once you have identified possible triggers, you can then take steps to avoid them or reduce their impact. For example, you may notice that quick rewarming after exposure to the cold triggers your cold urticaria. In this case, taking steps to warm up more gradually may help. This can include avoiding washing your hands or bathing with warm water immediately after cold exposure and avoiding sitting next to radiators when coming inside from cold weather. If avoiding your triggers is difficult, medical therapies may also help. These can include over-the-counter antihistamine medication, taken before exposure, prescription medications, such as omalizumab (Xolair), and epinephrine pens (Epi-Pen, Adrenaclick, Twinject), in case of severe allergic reactions or anaphylaxis. Your doctor may prescribe an epinephrine pen and recommend carrying it with you at all times. Epinephrine can help stop anaphylaxis and reduce your symptoms. […] Treatments for cold urticaria include identifying and avoiding possible triggers and taking antihistamine medications.
  • #61 Cold hives: Symptoms, causes, and treatment
    https://www.medicalnewstoday.com/articles/cold-hives
    There is no cure for cold hives, but treatment can reduce the symptoms. This may involve: […] Avoiding triggers: For some, avoiding triggers is enough to reduce the impact cold hives has on their life. This involves identifying the specific triggers of the hives, and then seeing if it is possible to reduce exposure to them. Keeping a symptom diary may help with this process. […] Antihistamines: For people whose triggers are difficult to avoid entirely, antihistamines can help. These medications reduce the amount of histamine in the body, and so reduce the symptoms of hives. People can take them before they become exposed to the cold (e.g., before getting into an unheated swimming pool) or when hives appear. […] Other medications: If antihistamines are not enough to manage cold hives, someone may take stronger medications that prevent allergic reactions, such as omalizumab (Xolair). This is a type of monoclonal antibody medication.
  • #62 Cold urticaria – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/cold-urticaria/symptoms-causes/syc-20371046
    Cold urticaria occurs most often in young adults. If you think you have this condition, check in with your healthcare team. Treatment usually includes steps to keep cold urticaria from happening, such as taking antihistamines and staying away from cold air and water. […] These tips may help stop cold urticaria from happening: Take an antihistamine available without a prescription as directed before being exposed to the cold. Protect your skin from the cold or sudden changes in temperature. If you’re going swimming, dip your hand in the water first to see if your skin responds. Stay away from ice-cold drinks and foods to keep your throat from swelling. If your healthcare professional prescribed an epinephrine autoinjector, keep it with you to help stop serious responses from happening. If you’re scheduled for surgery, talk with your surgeon ahead of time about your cold urticaria. The surgical team can take steps to help keep symptoms caused by cold from happening in the operating room.
  • #63 Cold urticaria // Middlesex Health
    https://middlesexhealth.org/learning-center/diseases-and-conditions/cold-urticaria
    Cold urticaria occurs most often in young adults. If you think you have this condition, check in with your healthcare team. Treatment usually includes steps to keep cold urticaria from happening, such as taking antihistamines and staying away from cold air and water. […] These tips may help stop cold urticaria from happening: Take an antihistamine available without a prescription as directed before being exposed to the cold. Protect your skin from the cold or sudden changes in temperature. If you’re going swimming, dip your hand in the water first to see if your skin responds. Stay away from ice-cold drinks and foods to keep your throat from swelling. If your healthcare professional prescribed an epinephrine autoinjector, keep it with you to help stop serious responses from happening. If you’re scheduled for surgery, talk with your surgeon ahead of time about your cold urticaria. The surgical team can take steps to help keep symptoms caused by cold from happening in the operating room.
  • #64 Cold Urticaria Symptoms and Causes | Valley Skin Institute
    https://www.valleyskininstitute.com/cold-urticaria-symptoms-and-causes/?srsltid=AfmBOopLs66H7NGqbWH7NeuXRk-EsbMdbnpYO9gxMrQl_em8foctq5_-
    The best way to prevent cold urticaria reactions is to avoid exposing your skin to cold air temperatures or cold water temperatures, or experiencing a rapid drop in body temperature. […] Taking special precautions before undergoing general anesthesia for surgery can help prevent cold urticaria reactions. If you have cold urticaria, tell your surgeon and anesthesiologist in advance so that they can take special precautions to keep you warm during your surgery. These precautions include: […] Monitoring your body temperature […] Maintaining a uniform warm temperature in the operating room […] Applying warming blankets as needed […] Warming intravenous (IV) fluids prior to infusion […] Prescribing pre-operative non-sedating antihistamine […] Considering the use of a systemic corticosteroid, which is a type of steroid […] Avoiding histamine-releasing drugs, such as opioids, and drugs with a high risk of inducing anaphylaxis (which is a serious type of allergic reaction).
  • #65 Cold urticaria
    https://dermnetnz.org/topics/cold-urticaria
    Cold urticaria can be diagnosed by applying an ice cube against the skin of the forearm for 15 minutes. A distinct red swollen rash should develop within minutes in the area exposed to the cold-stimulation test if a patient has cold urticaria. […] Patients with cold urticaria should learn to protect themselves from a rapid drop in body temperature. Aquatic activities (such as swimming and surfing) should always be under supervision. […] Cautious induction of cold tolerance may be successful (desensitisation), by gradually hardening the skin to cold conditions and then exposing the skin to it regularly, for example, by taking regular cold showers. […] The anaesthetist should be told in advance that the patient has cold urticaria. Staff must take precautions to keep the patient warm.
  • #66
    https://www.wyndly.com/blogs/learn/cold-urticaria?srsltid=AfmBOooH8XaOSXzRJP-CoE4QrAatjhMc-1ma6lo98S-vnCbwCvyAp4q3
    Next, plan ahead. Always check the weather forecast before leaving the house and prepare accordingly. If you anticipate being in cold environments, bring along hot drinks, heating pads, or warm blankets to help maintain your body temperature. […] Finally, take care of your overall health. Regular exercise, a balanced diet, and adequate sleep can help strengthen your immune system and decrease the likelihood of allergy hives flare-ups. […] Remember, these strategies are not a substitute for medical advice. Always consult a healthcare professional to develop a comprehensive management plan for cold urticaria.
  • #67 Understanding Cold and Heat-Induced Urticaria: Causes, Symptoms, and Management
    https://www.mamahealth.com/chronic-spontaneous-urticaria/cold-and-heat-induced
    Cold-induced urticaria (also called cold urticaria) is triggered by exposure to cold temperatures, such as cold air, water, or objects. When the skin is exposed to cold, histamine and other chemicals are released, causing hives to form. […] The first step in managing temperature-induced urticaria is to avoid known triggers. This may involve making lifestyle adjustments to minimize exposure to cold or heat. […] For Cold Urticaria: Dress Warmly: Wear appropriate clothing to protect skin from cold weather. Avoid Cold Water: Refrain from swimming in cold water and use lukewarm water for bathing. Use Insulated Gloves: Handle cold objects with insulated gloves to protect your skin. […] In some cases, gradual desensitization to cold or heat can help reduce sensitivity. This involves controlled exposure to the triggering temperature in a safe and monitored environment, allowing the body to build tolerance over time. […] Stress can exacerbate urticaria symptoms. Incorporating stress-reducing activities, such as yoga, meditation, and regular exercise, can help manage stress levels and potentially reduce the frequency of flare-ups.
  • #68
    https://www.wyndly.com/blogs/learn/cold-urticaria?srsltid=AfmBOooH8XaOSXzRJP-CoE4QrAatjhMc-1ma6lo98S-vnCbwCvyAp4q3
    Next, plan ahead. Always check the weather forecast before leaving the house and prepare accordingly. If you anticipate being in cold environments, bring along hot drinks, heating pads, or warm blankets to help maintain your body temperature. […] Finally, take care of your overall health. Regular exercise, a balanced diet, and adequate sleep can help strengthen your immune system and decrease the likelihood of allergy hives flare-ups. […] Remember, these strategies are not a substitute for medical advice. Always consult a healthcare professional to develop a comprehensive management plan for cold urticaria.
  • #69 Understanding Cold and Heat-Induced Urticaria: Causes, Symptoms, and Management
    https://www.mamahealth.com/chronic-spontaneous-urticaria/cold-and-heat-induced
    Cold-induced urticaria (also called cold urticaria) is triggered by exposure to cold temperatures, such as cold air, water, or objects. When the skin is exposed to cold, histamine and other chemicals are released, causing hives to form. […] The first step in managing temperature-induced urticaria is to avoid known triggers. This may involve making lifestyle adjustments to minimize exposure to cold or heat. […] For Cold Urticaria: Dress Warmly: Wear appropriate clothing to protect skin from cold weather. Avoid Cold Water: Refrain from swimming in cold water and use lukewarm water for bathing. Use Insulated Gloves: Handle cold objects with insulated gloves to protect your skin. […] In some cases, gradual desensitization to cold or heat can help reduce sensitivity. This involves controlled exposure to the triggering temperature in a safe and monitored environment, allowing the body to build tolerance over time. […] Stress can exacerbate urticaria symptoms. Incorporating stress-reducing activities, such as yoga, meditation, and regular exercise, can help manage stress levels and potentially reduce the frequency of flare-ups.
  • #70 Hives (urticaria): Causes, pictures, and treatments
    https://www.medicalnewstoday.com/articles/157260
    Some tips for preventing hives include: […] keeping a diary to see if any particular triggers cause them […] avoiding those triggers […] taking over-the-counter antihistamines when the pollen count is high, if pollen may be a trigger […] talking to a doctor about whether medications may be responsible […] using meditation and other relaxation techniques to manage stress […] choosing mild or fragrance-free soaps, skin creams, and detergents.
  • #71 Cold Urticaria: Symptoms, Causes, and Effective Home Remedies To Ease This Skin Condition
    https://www.netmeds.com/health-library/post/cold-urticaria-symptoms-causes-and-effective-home-remedies-to-ease-this-skin-condition?srsltid=AfmBOopC80XXnrFrwV7S9WCouJ1wJDZYDHstJ0iD1VU5lo1DPk0WRimG
    Cold urticaria occurs due to an overreaction of the skin’s immune system to cold stimuli. […] Reduce time spent in cold environments. […] Wear protective clothing, such as gloves and scarves, to safeguard the skin from cold air. […] Use lukewarm water instead of cold for bathing or washing hands. […] Over-the-counter antihistamine creams or oral antihistamines can help ease itching and swelling. […] Always consult a doctor before using them regularly. […] Apply a warm (not hot) compress to the affected regions to alleviate discomfort, soothe irritation and improve blood circulation. […] Use a gentle, fragrance-free moisturizer to shield the skin from dryness and irritation. […] Moisturize immediately after showering to lock in moisture. […] Consume a rich array of foods heaped with vitamin C, omega-3 fatty acids, and antioxidants, which help strengthen the immune system and reduce inflammation.
  • #72 Cold Allergy: What it is, Diagnosis, and Treatment – Creu Blanca
    https://www.paracelsosagasta.es/en/news/cold-allergy/
    The use of antihistamines helps prevent and control the symptoms of cold urticaria. Antihistamines reduce the skin reaction in patients with this condition when exposed to the cold. […] Additionally, keeping the skin well-hydrated helps avoid itching caused by the common dryness on cold days.
  • #73 Acute and Chronic Urticaria: Evaluation and Treatment | AAFP
    https://www.aafp.org/pubs/afp/issues/2017/0601/p717.html
    Urticaria is a common dermatologic condition that typically presents with intensely pruritic, well-circumscribed, raised wheals ranging from several millimeters to several centimeters or larger in size. […] The mainstay of treatment is avoidance of triggers, if identified. […] Methods of treatment for urticaria are the same for adults and children. The mainstay of treatment is avoidance of identified triggers. It is also recommended that patients avoid using aspirin, alcohol, and NSAIDs, as well as avoid wearing tight clothing, because these may worsen symptoms. […] If trigger avoidance is impossible, no trigger is identified, or symptom relief is needed despite trigger avoidance, H1-antihistamines are first-line pharmacotherapy. […] For improved symptom control, the medication should be dosed daily, rather than on an as-needed basis.
  • #74
    https://link.springer.com/article/10.1007/s40521-024-00366-9
    ColdA is a major and potentially life-threatening concern for a subset of ColdU patients. Early recognition of high-risk patients, coupled with education and preparedness of both patients and healthcare providers, is crucial for effectively managing this challenging condition. […] Patients at high risk for anaphylaxis require provision of AAIs. The COLD-CE study highlighted that only a minority of ColdA patients received adrenaline during their anaphylaxis episode or were prescribed an AAI. Recommendations for prescribing AAIs vary: Yee et al. and Alangari et al. advised that all pediatric patients with ColdUT should have AAIs, while Katsarou-Katsari et al. extended this recommendation to all adult patients with ColdUT. […] Patients at high risk of ColdA require not only comprehensive education but also regular medical follow-ups. Education is crucial, as patients who are unaware of their condition’s risks are more vulnerable to life-threatening complications. Key educational points include: Trigger avoidance: Patients must be advised to exercise caution during activities involving complete water immersion, such as swimming in the sea, lake or pool.
  • #75
    https://link.springer.com/article/10.1007/s40521-024-00366-9
    ColdA is a major and potentially life-threatening concern for a subset of ColdU patients. Early recognition of high-risk patients, coupled with education and preparedness of both patients and healthcare providers, is crucial for effectively managing this challenging condition. […] Patients at high risk for anaphylaxis require provision of AAIs. The COLD-CE study highlighted that only a minority of ColdA patients received adrenaline during their anaphylaxis episode or were prescribed an AAI. Recommendations for prescribing AAIs vary: Yee et al. and Alangari et al. advised that all pediatric patients with ColdUT should have AAIs, while Katsarou-Katsari et al. extended this recommendation to all adult patients with ColdUT. […] Patients at high risk of ColdA require not only comprehensive education but also regular medical follow-ups. Education is crucial, as patients who are unaware of their condition’s risks are more vulnerable to life-threatening complications. Key educational points include: Trigger avoidance: Patients must be advised to exercise caution during activities involving complete water immersion, such as swimming in the sea, lake or pool.
  • #76
    https://www.healio.com/news/allergy-asthma/20210809/omalizumab-effectively-treats-chronic-cold-urticaria
    Overall, four of the six patients who had a history of anaphylaxis had no further anaphylactic episodes with omalizumab. […] The researchers noted questions remain regarding the proper time for initiating omalizumab, the adequate treatment duration and dosage, and use of alternative immunomodulatory therapies. […] He also said three key unresolved questions remain, including defining the ideal treatment algorithm; whether omalizumab affects the rate of cold-induced anaphylaxis or, rather, whether controlling the CCU decreases its rate; and if a history of cold-induced anaphylaxis should prompt clinicians to consider omalizumab earlier, even if symptoms are controlled with a second-generation H1-antihistamine.
  • #77 Cold urticaria – ECARF
    https://www.ecarf.org/en/coldurticaria/
    Cold urticaria can become dangerous in rare cases, such as when hives appear all over the body after jumping into cold water. Magerl says that hives covering such a large area can be hard on the circulation. Significant amounts of fluids can seep from the blood into the skin. This can lead to a drop in blood pressure and eventually shock and loss of consciousness. Patients should be made aware of this possibility. Urticaria can also cause difficulties for people whose mucous membranes react to the cold. Whenever these patients eat ice cream or drink cold water, swelling can occur in the throat, making it difficult to breathe. […] Various medications are available for the treatment of cold urticaria. The hives can be prevented by avoiding cold stimuli by wearing warm clothing or using face cream, for example. But this is not always practical, so antihistamines are the next best option. Although they cannot cure the disease, they can reduce the symptoms. If they are not effective, the doctor can increase the dosage by four. […] The allergologist also points out that it is useful to pinpoint the threshold value in order to determine whether a certain type of treatment is working.
  • #78 Cold urticaria – ECARF
    https://www.ecarf.org/en/coldurticaria/
    Cold urticaria can become dangerous in rare cases, such as when hives appear all over the body after jumping into cold water. Magerl says that hives covering such a large area can be hard on the circulation. Significant amounts of fluids can seep from the blood into the skin. This can lead to a drop in blood pressure and eventually shock and loss of consciousness. Patients should be made aware of this possibility. Urticaria can also cause difficulties for people whose mucous membranes react to the cold. Whenever these patients eat ice cream or drink cold water, swelling can occur in the throat, making it difficult to breathe. […] Various medications are available for the treatment of cold urticaria. The hives can be prevented by avoiding cold stimuli by wearing warm clothing or using face cream, for example. But this is not always practical, so antihistamines are the next best option. Although they cannot cure the disease, they can reduce the symptoms. If they are not effective, the doctor can increase the dosage by four. […] The allergologist also points out that it is useful to pinpoint the threshold value in order to determine whether a certain type of treatment is working.
  • #79 Acute and Chronic Urticaria: Evaluation and Treatment | AAFP
    https://www.aafp.org/pubs/afp/issues/2017/0601/p717.html
    If symptomatic control is still not achieved, the third step is addition and titration of high-potency antihistamines as tolerated, such as hydroxyzine or the tricyclic antidepressant doxepin (possesses markedly more antihistaminic effect than diphenhydramine). […] Once symptoms are adequately controlled, physicians should consider stepping down treatment sequentially. […] If an underlying cause of chronic urticaria is identified, the condition should be treated or the patient referred to an appropriate subspecialist.
  • #80 Cold urticaria – ECARF
    https://www.ecarf.org/en/coldurticaria/
    Cold urticaria can become dangerous in rare cases, such as when hives appear all over the body after jumping into cold water. Magerl says that hives covering such a large area can be hard on the circulation. Significant amounts of fluids can seep from the blood into the skin. This can lead to a drop in blood pressure and eventually shock and loss of consciousness. Patients should be made aware of this possibility. Urticaria can also cause difficulties for people whose mucous membranes react to the cold. Whenever these patients eat ice cream or drink cold water, swelling can occur in the throat, making it difficult to breathe. […] Various medications are available for the treatment of cold urticaria. The hives can be prevented by avoiding cold stimuli by wearing warm clothing or using face cream, for example. But this is not always practical, so antihistamines are the next best option. Although they cannot cure the disease, they can reduce the symptoms. If they are not effective, the doctor can increase the dosage by four. […] The allergologist also points out that it is useful to pinpoint the threshold value in order to determine whether a certain type of treatment is working.
  • #81 Acute and Chronic Urticaria: Evaluation and Treatment | AAFP
    https://www.aafp.org/pubs/afp/issues/2017/0601/p717.html
    If symptomatic control is still not achieved, the third step is addition and titration of high-potency antihistamines as tolerated, such as hydroxyzine or the tricyclic antidepressant doxepin (possesses markedly more antihistaminic effect than diphenhydramine). […] Once symptoms are adequately controlled, physicians should consider stepping down treatment sequentially. […] If an underlying cause of chronic urticaria is identified, the condition should be treated or the patient referred to an appropriate subspecialist.
  • #82 Cold Urticaria: Symptoms, Causes, and Treatment
    https://resources.healthgrades.com/right-care/skin-hair-and-nails/cold-urticaria
    Cold urticaria is an allergic response that develops after exposure to the cold. It most often presents as a rash or hives. The main aim of cold urticaria treatment is to alleviate symptoms and prevent flare-ups. A key part of managing cold urticaria is learning and avoiding your personal triggers. To do this, you can start by recording your symptoms and note any activities that may have caused them. Once you have identified possible triggers, you can then take steps to avoid them or reduce their impact. For example, you may notice that quick rewarming after exposure to the cold triggers your cold urticaria. In this case, taking steps to warm up more gradually may help. This can include avoiding washing your hands or bathing with warm water immediately after cold exposure and avoiding sitting next to radiators when coming inside from cold weather. If avoiding your triggers is difficult, medical therapies may also help. These can include over-the-counter antihistamine medication, taken before exposure, prescription medications, such as omalizumab (Xolair), and epinephrine pens (Epi-Pen, Adrenaclick, Twinject), in case of severe allergic reactions or anaphylaxis. Your doctor may prescribe an epinephrine pen and recommend carrying it with you at all times. Epinephrine can help stop anaphylaxis and reduce your symptoms. […] Treatments for cold urticaria include identifying and avoiding possible triggers and taking antihistamine medications.
  • #83 Diagnosis and management of cold urticaria – PubMed
    https://pubmed.ncbi.nlm.nih.gov/26919357/
    Cold urticaria is a physical urticaria characterized by a localized or systemic eruption of papules upon exposure of the skin to cold air, liquids, and/or objects. […] Avoidance of cold exposure is the most effective prophylactic measure. […] In mild to moderate cases, the primary goal of therapy is to improve the patient’s quality of life. […] In more severe cases, treatment measures to protect the patient’s airway, breathing, and circulation may be necessary.
  • #84 Understanding Cold Urticaria and Its Treatment | Coconote
    https://coconote.app/notes/68621846-f7a0-4542-8579-ca2eca355c86
    Avoidance of Cold: Primary preventive measure. […] Prevention: Avoid cold temperatures, food, and drinks. […] Cold urticaria requires careful management and proactive measures to prevent severe reactions. […] Consultation with healthcare providers is crucial for effective management and treatment.
  • #85 Cold Urticaria | Allergy and Clinical
    https://www.allergyclinical.com/blog/cold-urticaria/
    Cold urticaria is a condition that affects the skin. It is characterized by the development of reddish, itchy welts (hives) and/or swelling (angioedema) within minutes after skin exposure to cold. […] If you have experienced potential symptoms of cold urticaria, make an appointment with one of our physicians. […] Once a diagnosis has been made, potential treatments may include the following: […] Prevention Tips: […] Protect skin from cold or sudden changes in temperature […] Swimming Precautions: never swim alone test water temperature first swimming partner should be trained in the use of auto-injectable epinephrine […] Avoid ice cold drinks and food […] If having surgery, notify surgeon regarding your cold urticaria. There are steps that can be taken to help prevent symptoms in the OR. […] Although there is no cure for cold urticaria, it can usually be controlled with cold avoidance and antihistamine therapy.
  • #86 Cold urticaria – Diagnosis & treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/cold-urticaria/diagnosis-treatment/drc-20371051
    In some people, cold urticaria goes away on its own after weeks or months. In others, it lasts longer. While there is no cure for the condition, treatment and taking steps to avoid cold urticaria can help. […] Your healthcare professional may recommend that you try to keep symptoms from happening or reduce those symptoms using home remedies. These remedies include antihistamines available without a prescription and staying away from the cold. If these treatments don’t help, you may need prescription medicine. […] If you know you’re going to be exposed to the cold, take an antihistamine ahead of time to help keep a response from happening. […] Antihistamines block the release of histamine that causes symptoms. These medicines can be used to treat mild symptoms of cold urticaria or to keep a response from happening. Medicines available without a prescription include forms of loratadine and cetirizine.
  • #87 Cold urticaria
    https://www.mymlc.com/health-information/diseases-and-conditions/c/cold-urticaria2/
    Cold urticaria occurs most frequently in young adults. If you think you have this condition, consult your doctor. Treatment usually includes preventive steps such as taking antihistamines and avoiding cold air and water. […] The following tips may help prevent a recurrent episode of cold urticaria: Take an over-the-counter antihistamine before cold exposure. Take medications as prescribed. Protect your skin from the cold or sudden changes in temperature. If you’re going swimming, dip your hand in the water first and see if you experience a skin reaction. Avoid ice-cold drinks and food to prevent swelling of your throat. If your doctor prescribed an epinephrine autoinjector (EpiPen, Auvi-Q, others), keep it with you to help prevent serious reactions. If you’re scheduled for surgery, talk with your surgeon beforehand about your cold urticaria. The surgical team can take steps to help prevent cold-induced symptoms in the operating room. […] In some people, cold urticaria goes away on its own after weeks or months. In others, it lasts longer. There is no cure for the condition, but treatment and preventive steps can help.
  • #88 Cold Urticaria | Allergy and Clinical
    https://www.allergyclinical.com/blog/cold-urticaria/
    Cold urticaria is a condition that affects the skin. It is characterized by the development of reddish, itchy welts (hives) and/or swelling (angioedema) within minutes after skin exposure to cold. […] If you have experienced potential symptoms of cold urticaria, make an appointment with one of our physicians. […] Once a diagnosis has been made, potential treatments may include the following: […] Prevention Tips: […] Protect skin from cold or sudden changes in temperature […] Swimming Precautions: never swim alone test water temperature first swimming partner should be trained in the use of auto-injectable epinephrine […] Avoid ice cold drinks and food […] If having surgery, notify surgeon regarding your cold urticaria. There are steps that can be taken to help prevent symptoms in the OR. […] Although there is no cure for cold urticaria, it can usually be controlled with cold avoidance and antihistamine therapy.