Materiały źródłowe

• #1 Pancreatic Disease Diagnosis & Treatment | ColumbiaDoctors

  https://www.columbiadoctors.org/specialties/gastroenterology/our-services/pancreatic-disease

  The Pancreatic Cyst Surveillance Program focuses on the comprehensive and multidisciplinary evaluation and treatment of patients with cystic lesions in the pancreas. Our goal is to identify patients who require further diagnostics, immediate treatment, or long-term surveillance. […] By offering a practice that monitors patients with known precursors to this disease, we strive to take a positive step toward fighting pancreatic cancer.

• #2 Pancreatic Cysts: To Treat or Not to Treat? – NYU Langone Health Physician Focus

  https://physicianfocus.nyulangone.org/pancreatic-cysts-to-treat-or-not-to-treat/

  My career has focused on the prevention and early detection of pancreatic cancer because I believe this is one of the most effective ways to improve outcomes and survival for this disease. […] Despite only a small proportion of cysts becoming malignant, its essential to follow patients over time to inform evidence-based best practices. […] Im optimistic that we will be able to routinely offer different methods of endoscopic ablation of cysts to our patients.

• #3 Pancreatic Cysts – Types, Symptoms, Causes, Treatment, Prevention PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact

  https://www.pacehospital.com/pancreatic-cysts-types-causes-symptoms-complications-treatment-prevention

  Certain lifestyle changes and habits can reduce the risk of developing cysts, even though some cannot be avoided. […] Refraining from Drinking Too Much Alcohol: Reducing alcohol consumption can help avoid pancreatitis, which can cause pancreatic cysts. […] Managing gallstones: Gallstones are a significant cause of pancreatitis, and addressing them is vital to prevent future pancreatic cysts. […] Exercising regularly: Regular exercise helps maintain a healthy weight and supports pancreatic function in general. […] Monitoring Blood Sugar Levels: Especially in diabetics, controlling blood sugar can reduce the risk of pancreatic issues, including cysts. […] A nutritious diet: Maintaining pancreatic health and lowering the risk of cyst formation can be achieved by eating a balanced diet rich in fruits, vegetables, and whole grains.

• #4 Pancreatic Cysts

  https://www.digestivespecialists.com/condition/pancreatic-cysts

  There are many factors that you cannot control in whether you will develop pancreatic cysts or pseudocysts. Because pancreatitis can result in the formation of pseudocysts, there is one lifestyle change that you can make to prevent pancreatitis. Heavy alcohol use is associated with pancreatitis, so limit your alcohol or make the decision to stop drinking alcohol. If you are a heavy user of alcohol consider talking to your doctor about getting support. There are many local programs that are available to you to help discontinue drinking. […] Diet can also help prevent pancreatic pseudocysts. A diet that is high in fruits, vegetables and lean proteins and low in carbohydrates and cholesterol will give you the best chance to avoid pseudocyst formation.

• #5 Pancreatic Cysts

  https://www.uvmhealth.org/medcenter/conditions-and-treatments/pancreatic-cysts

  The best way to avoid a pseudocyst, the most common type of pancreatic cyst, is to avoid pancreatitis. Pancreatitis is usually caused by gallstones or heavy alcohol use. If gallstones trigger your pancreatitis, you may need to have your gallbladder surgically removed (called cholecystectomy). Drinking less or no alcohol also can reduce your risk of pancreatitis.

• #6 Pancreatic Cysts: Symptoms, Types, Treatment, and Risk Factors

  https://www.healthline.com/health/cyst-on-pancreas

  There are several steps you can take to prevent a pancreatic cyst from occurring again, including: […] Avoiding pancreatitis […] Removing the gallbladder can reduce the risk of pancreatitis for individuals with gallstones. […] Reducing alcohol consumption can reduce the risk of pancreatitis. […] Restricting your daily fat intake to 30 to 50 grams can also reduce your risk of pancreatic cysts. […] You should also avoid sugary sodas and drinks with cream (like eggnog), and fried foods (including fried vegetables).

• #7 Understanding Pancreatic Cysts: Symptoms, Types and Treatment

  https://www.hoag.org/specialties-services/digestive-health/diseases-conditions/pancreatic-cysts-intraductal-papillary-mucinous/

  Researchers cant yet explain why some people develop pancreatic cysts while others of similar age, lifestyle, diet, etc. do not. […] One of the best ways to reduce your risk of pancreatic cysts is to reduce your risk of pancreatitis, which is a major reason pancreatic cysts develop. Potential ways to reduce your risk of pancreatitis include: […] Avoid developing gallstones small, pebble-like deposits in the gallbladder which are the most common reason for acute pancreatitis by eating a healthy, balanced diet and avoiding fatty or high-cholesterol foods. […] Maintain a healthy weight by eating a nutritious diet and getting regular exercise. […] Limit your intake of alcohol, especially if youve previously had acute pancreatitis related to binge drinking or alcoholism. […] Get regular checkups, including blood work that can suggest changes in pancreatic function.

• #8 Pancreatic Cysts, Cancer and Awareness: Answers from an Expert | Rutgers Cancer Institute of New Jersey

  https://cinj.org/pancreatic-cysts-cancer-and-awareness-answers-expert

  While there is no sure way to prevent pancreatic cancer, physicians can make an impact on prevention immediately among people who have an increased risk of developing pancreatic cancer or detect the disease early when it is in an operable stage. […] More importantly, the modifiable factors include tobacco use, obesity, chronic pancreatitis, diabetes and pancreatic cysts. We include pancreatic cysts in the modifiable category since many pancreatic cysts are a marker for increased risk of pancreas cancer and when followed/ surveyed appropriately, we believe we can intervene at appropriate times and reduce the risk of developing pancreas cancer. […] The practice of preventative medicine in the setting of pancreas cancer can greatly impact the development of pancreas cancer and potentially prevent its development.

• #9 Pancreatic Cysts: Advanced Cancer Prevention | UVA Health

  https://uvahealth.com/services/pancreatic-cancer/pancreatic-cysts

  Pancreatic cysts increase your risk for cancer. We can get ahead of pancreatic cancer by finding and treating pancreatic cysts. […] That’s why you need to get screened and know your risk. We can look for cysts in your pancreas. Knowing they exist is the first step. […] Many cysts are not cancer. If you lack pain or health problems, we’ll watch to see if the cysts change or grow. […] Whatever kind you have, our team watches cysts for changes. With careful monitoring, we can see if they start to become pancreatic cancer. An early diagnosis gives us the chance of a successful treatment. […] Assess risk factors […] Offer nutrition counseling […] Review imaging results […] Determine the need for more diagnostics […] Perform a clinical exam […] Enter you in a program for quitting smoking, if necessary […] Give you directions and advice for next steps.

• #10 Pancreatic cysts

  https://johnsonmemorial.org/jmh-health/disease-conditions/con-20375978

  The best way to avoid pseudocysts is to avoid pancreatitis, which is usually caused by gallstones or heavy alcohol use. If gallstones are triggering pancreatitis, you may need to have your gallbladder removed. If your pancreatitis is due to alcohol use, not drinking can reduce your risk.

• #11 Pancreatic cysts

  https://johnsonmemorial.org/jmh-health/disease-conditions/con-20375978

  The best way to avoid pseudocysts is to avoid pancreatitis, which is usually caused by gallstones or heavy alcohol use. If gallstones are triggering pancreatitis, you may need to have your gallbladder removed. If your pancreatitis is due to alcohol use, not drinking can reduce your risk.

• #12 Understanding Pancreatic Cysts: Symptoms, Types and Treatment

  https://www.hoag.org/specialties-services/digestive-health/diseases-conditions/pancreatic-cysts-intraductal-papillary-mucinous/

  The goal of a pancreatic cyst surveillance program is to identify any changes in the cyst that may indicate an increased risk of developing into pancreatic cancer. This allows for early detection and treatment, which can improve outcomes and increase the chances of a successful recovery. […] Regular surveillance is crucial for ensuring the best possible outcome for patients with pancreatic cysts. […] If pancreatic cysts are causing symptoms or if they are at a high risk for becoming cancerous, the preferred treatment is surgical removal of the cysts. […] For most cysts that arent producing symptoms and have little to no risk of becoming cancerous, however, your doctor may recommend leaving the cyst in place and observing it over time.

• #13 Pancreatic Cysts | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/pancreatic-cysts

  Most pancreatic cysts are benign (not cancer) and have a low chance of causing harm or symptoms. But some are precancerous, which means they can become pancreatic cancer. Its important to find out what type of cyst you have. […] Our pancreatic cyst specialists recommend that people diagnosed with cysts should be closely monitored. […] The program will monitor you throughout your life. Its important to know you may still need ongoing monitoring even after we remove the cysts during surgery. […] This information can help predict whether a precancerous cyst will turn into cancer. It guides decisions about monitoring and treatment.

• #14 Researchers Refine a Safe, Minimally Invasive Method to Destroy Precancerous Pancreatic Cysts – Medical Update

  https://medicalupdate.pennstatehealth.org/gastroenterology-gi-surgery/destroy-pancreatic-cysts/

  Most pancreatic cysts can be managed with surveillance, which generally means keeping an eye on them with annual magnetic resonance imaging or computed tomography (CT). […] If we can develop a way to minimally invasively eradicate these cystic tumors without a morbid surgery, youre talking about a real advancement in a patient population that is in desperate need for better treatment options. […] This showed that alcohol is not required for effective cyst ablation, and that when alcohol is removed from the process, there is a dramatic reduction in associated adverse events. […] Were hopeful that CHARM II will define this as a safe and effective technique in appropriately selected patients, Dr. Moyer says.

• #15 Diagnosis and management of asymptomatic neoplastic pancreatic cysts – American Gastroenterological AssociationAGA Logo_Horizontal

  https://gastro.org/clinical-guidance/diagnosis-and-management-of-asymptomatic-neoplastic-pancreatic-cysts/

  1. AGA recommends that before starting any pancreatic cyst surveillance program, patients should have a clear understanding of programmatic risks and benefits. […] 2. AGA suggests that patients with pancreatic cysts <3 cm without a solid component or a dilated pancreatic duct undergo magnetic resonance imaging (MRI) for surveillance in 1 year and then every 2 years for a total of 5 years if there is no change in size or characteristics. [...] 3. AGA suggests that pancreatic cysts with at least two high-risk features, such as size ≥3 cm, a dilated main pancreatic duct, or the presence of an associated solid component, should be examined with endoscopic ultrasonography (EUS) – fine-needle aspiration (FNA). [...] 4. AGA suggests that patients without concerning EUS-FNA results should undergo MRI surveillance after 1 year and then every 2 years to ensure no change in risk of malignancy.

• #16 Pancreatic Cysts: A Q&A with James Farrell, MD < Yale School of Medicine

  https://medicine.yale.edu/news-article/pancreatic-cysts-james-farrell-md/

  One of the high-risk groups prone to developing pancreatic cancer are those who have pancreatic cysts. About 25% of all pancreatic cancers arise from pancreas cysts. […] If we can better identify and respond to pancreatic cysts, we may be able to prevent them from turning into a dangerous cancer. […] Physicians must consider the cyst size and other imaging features, as well as patient cancer risk factors and other coexisting medical conditions. […] It’s ultimately a balance between not missing a cancer and not sending too many patients for unnecessary surgery or tests. […] Preventing or detecting early pancreatic cancer is a significant challenge.

• #17 New Algorithm Helps Bring Standardized Care for Pancreatic Cysts Treatment | University Hospitals

  https://www.uhhospitals.org/for-clinicians/articles-and-news/articles/2019/02/standardizing-care-for-pancreatic-cysts

  Pancreatic cysts are a clinical conundrum for pancreatologists, says Jordan Winter, MD, Chief of Surgical Oncology, University Hospitals Cleveland Medical Center, and Associate Professor of Surgery, Case Western Reserve University School of Medicine. […] To help pancreatologists determine the most appropriate treatment, Dr. Winter and his UH Digestive Health Institute colleagues developed a pancreatic cyst evaluation, surveillance and treatment algorithm. […] Standardization ensures patients don’t get lost in follow-up, Dr. Winter says. It also ensures patients don’t get overtreated with either unnecessary surgery or MRIs. […] The American College of Gastroenterology (ACG) recommends different levels of surveillance for patients with intraductal papillary mucinous neoplasms (IPMNs) or mucinous cystic neoplasms (MCNs), both of which have a higher risk of progressing to cancer.

• #18 New Algorithm Helps Bring Standardized Care for Pancreatic Cysts Treatment | University Hospitals

  https://www.uhhospitals.org/for-clinicians/articles-and-news/articles/2019/02/standardizing-care-for-pancreatic-cysts

  According to the UH algorithm, healthy patients with a long life expectancy (in light of an estimated 8 percent risk of pancreatic cancer at 10 years in cysts that are around 1.5 cm in size) are strong candidates for surgery. […] We don’t want to perform unnecessary surgery, but we don’t want to leave in a potentially cancerous cyst, Dr. Winter says. […] Because the probability of a cyst developing into cancer remains low, surveillance is a doctor’s best tool. […] The pancreatic cyst algorithm will play an important role in the new UH Pancreatic Cyst Clinic, which launches in May 2019. […] Once a week, we can follow and help guide reliable surveillance of pancreatic cysts, Dr. Winter says. […] Both the clinic and the algorithm are an example of process innovation not as attention-grabbing as technical innovation, but an important step to improving efficiency and optimizing care.

• #19 Diagnosis and management of asymptomatic neoplastic pancreatic cysts – American Gastroenterological AssociationAGA Logo_Horizontal

  https://gastro.org/clinical-guidance/diagnosis-and-management-of-asymptomatic-neoplastic-pancreatic-cysts/

  5. AGA suggests that significant changes in the characteristics of the cyst, including the development of a solid component, increasing size of the pancreatic duct, and/or diameter ≥3 cm, are indications for EUS-FNA. […] 6. AGA suggests against continued surveillance of pancreatic cysts if there has been no significant change in the characteristics of the cyst after 5 years of surveillance or if the patient is no longer a surgical candidate. […] 7. AGA suggests that patients with both a solid component and a dilated pancreatic duct and/or concerning features on EUS and FNA should undergo surgery to reduce the risk of mortality from carcinoma. […] 8. AGA recommends that if surgery is considered for a pancreatic cyst, patients are referred to a center with demonstrated expertise in pancreatic surgery.

• #20 Diagnosis and management of asymptomatic neoplastic pancreatic cysts – American Gastroenterological AssociationAGA Logo_Horizontal

  https://gastro.org/clinical-guidance/diagnosis-and-management-of-asymptomatic-neoplastic-pancreatic-cysts/

  9. AGA suggests that patients with invasive cancer or dysplasia in a cyst that has been surgically resected should undergo MRI surveillance of any remaining pancreas every 2 years. […] 10. AGA suggests against routine surveillance of pancreatic cysts without high-grade dysplasia or malignancy at surgical resection.

• #21 Pancreatic Cyst Clinic | MD Anderson Cancer Center

  https://www.mdanderson.org/patients-family/diagnosis-treatment/care-centers-clinics/gastrointestinal-cancer-center/pancreatic-cyst-clinic.html

  New research focuses on pancreatic cyst prevention and growth […] Kim and his colleagues, including Florencia McAllister, M.D., are working on designing a clinical trial to detect precancerous cysts or to develop vaccines to prevent pancreatic cyst growth or progression. […] If we can get the immune system to attack antigens on the surface of problematic cysts, we could potentially keep them from growing, or get rid of them altogether, Kim says.

• #22 Pancreatic Cysts Are Monitored in New Trial Aimed at Reducing Cancer Risk Through Targeted Screening | Division of Cancer Prevention

  https://prevention.cancer.gov/news-and-events/blog/pancreatic-cysts-are-monitored-new-trial-aimed-reducing-cancer-risk-through

  In a new NCI-sponsored study now recruiting participants, investigators will evaluate two different screening strategies for non-cancerous pancreatic cysts to determine which works best at detecting early malignancy. […] Accurately predicting which cysts pose the highest cancer risk is essential to improving prevention and early detection. […] The screening trial aims to address these concerns. […] During the trial, doctors will recommend surgery to any participant in the study who develops presumed risk factors for a cancerous lesion, such as jaundice in the skin and eyes due to a pancreatic obstruction; specific changes in the cyst wall; or a drainage problem in the main pancreatic duct. […] Among the clinical trials in which the hospital participates, is a randomized study looking at how to stop cyst progression to cancer. […] Participants are first tested for an anti-inflammatory marker identified in cyst fluid, then receive either an anti-inflammatory drug or a placebo to see if there’s a decrease in cyst growth.

• #23 Innovative and Minimally Invasive Techniques for Pancreatic Cyst Ablation and Cancer Prevention – Medical Update

  https://medicalupdate.pennstatehealth.org/gastroenterology-gi-surgery/innovative-and-minimally-invasive-techniques-for-pancreatic-cyst-ablation-and-cancer-prevention/

  Given these problems, alternative approaches toward cyst management have been explored. Among these, Moyer reports, endoscopic ultrasound-guided fine needle infusion (EUS-FNI) is an innovative and promising approach. […] Moyer expects that by eliminating ethanol, safety will improve, while choosing chemotherapeutic agents specifically for pancreatic neoplasia will potentially increase rates of cyst resolution. […] If successful, the minimally invasive aspect of the protocol has the potential to become more broadly used for pancreatic cancer prevention in appropriately selected patients.

• #24 Is antibiotic prophylaxis necessary after endoscopic ultrasound–guided fine-needle aspiration of pancreatic cysts?

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9726434/

  Current society guidelines recommend antibiotic prophylaxis for 3 to 5 days after endoscopic ultrasoundguided fine-needle aspiration (EUS-FNA) of pancreatic cystic lesions (PCLs). […] The incidence of infection after EUS-FNA of PCLs is negligible. Routine use of postprocedural antibiotics does not add a significant benefit. […] The risk of infection after EUS-FNA of pancreatic cysts is minimal, and prophylactic antibiotic administration after this procedure does not seem to offer additional benefits for preventing cystic or systemic infection. […] Our data suggest that postprocedural prophylactic antibiotics have a limited role in patients undergoing EUS-FNA of pancreatic cysts.

• #25 Is antibiotic prophylaxis necessary after endoscopic ultrasound–guided fine-needle aspiration of pancreatic cysts?

  https://www.e-ce.org/journal/view.php?number=7670

  Current society guidelines recommend antibiotic prophylaxis for 3 to 5 days after endoscopic ultrasoundguided fine-needle aspiration (EUS-FNA) of pancreatic cystic lesions (PCLs). The overall quality of the evidence supporting this recommendation is low. […] The incidence of infection after EUS-FNA of PCLs is negligible. Routine use of postprocedural antibiotics does not add a significant benefit. […] The current American Society for Gastrointestinal Endoscopy guidelines recommend administration of antibiotics for 3 to 5 days after EUS-FNA of PCLs. […] Our study showed that the incidence of localized or systemic infection after EUS-FNA was negligible with a single dose of periprocedural IV antibiotics, without the need for 3 to 5 days of postprocedural antibiotics. […] The results of our study showed that the risk of infection after EUS-FNA of PCLs is very low, as demonstrated by the group of patients who did not receive postprocedural antibiotics for prophylaxis.

• #26 A Meta-analysis Confirms That Antibiotic Prophylaxis Is Not Needed for Endoscopic Ultrasound-Guided Fine Needle Aspiration of Pancreatic Cysts – PubMed

  https://pubmed.ncbi.nlm.nih.gov/32645317/

  Antibiotic Prophylaxis Is Not Required for Endoscopic Ultrasonography-Guided Fine-Needle Aspiration of Pancreatic Cystic Lesions, Based on a Randomized Trial. […] Use of antibiotic prophylaxis is not needed for endoscopic ultrasound-guided fine-needle aspiration of pancreatic cysts: a meta-analysis. […] Antibiotics Do Not Decrease the Rate of Infection After Endoscopic Ultrasound Fine-Needle Aspiration of Pancreatic Cysts.

• #27 Is antibiotic prophylaxis necessary after endoscopic ultrasound–guided fine-needle aspiration of pancreatic cysts?

  https://www.e-ce.org/journal/view.php?number=7670

  Thus, our data suggest that postprocedural prophylactic antibiotics have a limited role in patients undergoing EUS-FNA of pancreatic cysts. The routine use of antibiotics may have some negative outcomes, such as added cost and, more important, increased drug resistance and increased risk of secondary infections. […] In conclusion, the risk of infection after EUS-FNA of pancreatic cysts is minimal, and prophylactic antibiotic administration after this procedure does not seem to offer additional benefits for preventing cystic or systemic infection.

• #28 Pancreatic Cysts: Symptoms, Causes & Diagnosis

  https://tap.health/pancreatic-cysts-symptoms/

  Early detection is key. Regular check-ups, particularly for individuals with a family history of pancreatic cancer or diabetes, are essential. […] While not all pancreatic cysts are preventable, maintaining a healthy lifestyle can significantly reduce your risk. This includes a balanced diet, avoiding excessive alcohol consumption, and not smoking. Regular health checkups, particularly for individuals with a family history of pancreatic cysts or diabetes, are vital for early detection. Early detection is key, as it allows for timely intervention and management of any potentially problematic cysts. […] In some cases, particularly for individuals with a family history of pancreatic cancer or other risk factors, prophylactic surgery may be considered.

• #29 Pancreatic Cysts | Treatment for Pancreatic Cysts & Stomach Issues From Expert Pancreatic Doctors – Cleveland, Ohio | University Hospitals

  https://www.uhhospitals.org/services/digestive-health-services/conditions-and-treatments/pancreas-and-biliary-tract/pancreatic-cyst

  Pancreatic cysts are often found when imaging for an unrelated issue. […] Even if you have a benign pancreatic cyst, it is vital to identify the structure and have it carefully monitored by a specialized team. […] We offer highly individualized care that includes patient education about a healthy diet and avoiding pancreatoxic substances like tobacco and alcohol that can irritate the pancreas. […] Some of the risk factors for pancreatic cysts are within your control. For improved pancreatic health, work with your doctor to reduce your risk by cutting down your alcohol intake and focusing on a healthy lifestyle.

• #30 Do pancreatic cysts become cancerous? | Roswell Park Comprehensive Cancer Center – Buffalo, NY

  https://www.roswellpark.org/cancertalk/202302/do-pancreatic-cysts-become-cancerous

  The short answer is no the vast majority of pancreatic cysts do not become cancerous. […] Cysts that produce mucin, or mucous, are considered pre-cancerous in nature. […] Cysts that are pre-cancerous may need further evaluation, either via additional dedicated imaging or specialized endoscopic procedures, Dr. Prabhu says. „Even among those cysts that are deemed pre-cancerous, very few of them end up becoming cancer.” […] The first step is learning what kind of cyst you have, and whether it poses any further risk to your health. […] It is critical that patients with pancreatic cysts seek out clinicians who have extensive experience with pancreatic tumors and pancreatic pathology. […] Most pancreatic cysts do not require treatment, explains Dr. Prabhu. For the vast majority, proper treatment is continued observation by an experienced clinician.

• #31 Pancreatic Cysts Treatment In SG | United Gastro and Endoscopy Clinic

  https://gastroclinic.com.sg/conditions-to-treat/biliary-pancreas/pancreatic-cysts/

  Can Pancreatic Cysts be Prevented? Since the exact causes of pancreatic cysts are not always known, specific prevention methods are limited. However, maintaining a healthy lifestyle, avoiding excessive alcohol consumption, and managing conditions like pancreatitis or other pancreatic diseases may help reduce the risk of developing cysts. […] Regular follow-up visits with a doctor are essential for individuals diagnosed with pancreatic cysts to monitor the cysts growth and assess any changes in symptoms. Its crucial to adopt a healthy diet, avoid smoking and excessive alcohol consumption, and promptly report any new or worsening symptoms to the medical team. Proactively managing ones health can aid in early detection and appropriate management if needed.

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