Materiały źródłowe

• #1 Silicosis and Crystalline Silica Exposure: What Physicians Need to Know

  https://www.health.ny.gov/environmental/investigations/silicosis/providerfact.htm

  Silicosis is an incurable interstitial fibronodular lung disease frequently characterized by pulmonary fibrosis as the result of exposure to respirable crystalline silica dust. Workers in industries such as mining, manufacturing, demolition, agriculture, construction, stone cutting, and pottery are all at risk for developing silicosis. […] If you suspect your patient may suffer from an occupational disease, the New York State Occupational Health Clinic Network is a statewide network of clinics specially equipped to handle workplace illness/injury, which providers may use for patient consultations and referrals. […] Should your patient present with signs and symptoms of respiratory disease, consider occupational exposure sources. Determining whether your patient has any workplace silica exposure is the first step towards preventing silicosis.

• #2 Silicosis | Health & Human Services

  https://hhs.iowa.gov/epi-manual-guide-surveillance-investigation-and-reporting/environmental-disease/silicosis

  Silicosis is an irreversible but preventable disease, and is the illness most closely associated with occupational exposure to silica dust. […] The symptoms of silicosis are a cough, with or without sputum, chest tightness, and shortness of breath, particularly on exertion. […] Surveillance of exposed workers with respiratory questionnaires, spirometry, and chest x-rays is recommended. […] As part of its National Emphasis Program on Silica, OSHA recommends that employers medically monitor all workers who may be exposed to silica dust levels at or above one-half the PEL. […] Although early treatment is generally supportive care, additional treatment options may be used to aid patient comfort and improve quality of life. […] Patients with airway obstruction may be treated empirically with bronchodilators and inhaled corticosteroids.

• #3 Silicosis and Crystalline Silica Exposure: What Physicians Need to Know

  https://www.health.ny.gov/environmental/investigations/silicosis/providerfact.htm

  Silicosis is an incurable interstitial fibronodular lung disease frequently characterized by pulmonary fibrosis as the result of exposure to respirable crystalline silica dust. Workers in industries such as mining, manufacturing, demolition, agriculture, construction, stone cutting, and pottery are all at risk for developing silicosis. […] If you suspect your patient may suffer from an occupational disease, the New York State Occupational Health Clinic Network is a statewide network of clinics specially equipped to handle workplace illness/injury, which providers may use for patient consultations and referrals. […] Should your patient present with signs and symptoms of respiratory disease, consider occupational exposure sources. Determining whether your patient has any workplace silica exposure is the first step towards preventing silicosis.

• #4 Silicosis | Health & Human Services

  https://hhs.iowa.gov/epi-manual-guide-surveillance-investigation-and-reporting/environmental-disease/silicosis

  Silicosis is an irreversible but preventable disease, and is the illness most closely associated with occupational exposure to silica dust. […] The symptoms of silicosis are a cough, with or without sputum, chest tightness, and shortness of breath, particularly on exertion. […] Surveillance of exposed workers with respiratory questionnaires, spirometry, and chest x-rays is recommended. […] As part of its National Emphasis Program on Silica, OSHA recommends that employers medically monitor all workers who may be exposed to silica dust levels at or above one-half the PEL. […] Although early treatment is generally supportive care, additional treatment options may be used to aid patient comfort and improve quality of life. […] Patients with airway obstruction may be treated empirically with bronchodilators and inhaled corticosteroids.

• #5 What is Silicosis? | Texas DSHS

  https://www.dshs.texas.gov/environmental-surveillance-toxicology/occupational-health/asbestosis-and-silicosis/what-is-silicosis

  Silicosis is a respiratory disease. It occurs from long-term inhalation of respirable crystalline silica dust. […] The negative health effects associated with silicosis usually take years to develop. […] As the disease advances, the following occurs: Shortness of breath becomes worse, cough becomes worse, lung x-rays show scar tissue, increased tiredness, loss of appetite, weakened immune system, which manifests as other illnesses (like tuberculosis). This may result in fever, weight loss, night sweats, chest pains, and/or respiratory failure. […] What can a worker do to help prevent silicosis? Avoid working in silica dust whenever possible. Check that all ventilation systems and protective equipment are in good repair and working correctly. Use Personal Protective Equipment (PPE) and use it properly. Don’t smoke. Smoking breaks down the body’s defenses and makes it hard for your lungs to remove dust. Shower and change clothes after working in contaminated areas before getting in your car and going home. Get regular medical checkups, with pulmonary function tests and x-rays. […] Who is responsible for reporting silicosis? Physicians, health professionals, anyone in charge of a medical laboratory, blood bank, mobile unit, or other facility where an examination reveals evidence of silicosis.

• #6 Silicosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK594245/

  In individuals exposed to silica, diagnosing silicosis early and counseling patients on avoiding further RCS exposure and smoking cessation is essential to disease management. […] A coordinated effort of primary care practitioners, pulmonologists, nursing staff, occupational health specialists, and transplant surgeons will lead to the best patient outcomes. […] Nursing staff members are a valuable part of the healthcare team, as they often spend the most time in close contact with the patient and frequently form interpersonal relationships with them. […] Reassurance and gentle encouragement to reinforce essential lifestyle changes can immensely impact patients lives. […] Occupational health nurses are specifically beneficial, as they are trained to provide education on risk factors and prevention strategies at worksites.

• #7 Silicosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK594245/

  In individuals exposed to silica, diagnosing silicosis early and counseling patients on avoiding further RCS exposure and smoking cessation is essential to disease management. […] A coordinated effort of primary care practitioners, pulmonologists, nursing staff, occupational health specialists, and transplant surgeons will lead to the best patient outcomes. […] Nursing staff members are a valuable part of the healthcare team, as they often spend the most time in close contact with the patient and frequently form interpersonal relationships with them. […] Reassurance and gentle encouragement to reinforce essential lifestyle changes can immensely impact patients lives. […] Occupational health nurses are specifically beneficial, as they are trained to provide education on risk factors and prevention strategies at worksites.

• #8 Silicosis | Health & Human Services

  https://hhs.iowa.gov/epi-manual-guide-surveillance-investigation-and-reporting/environmental-disease/silicosis

  Silicosis is an irreversible but preventable disease, and is the illness most closely associated with occupational exposure to silica dust. […] The symptoms of silicosis are a cough, with or without sputum, chest tightness, and shortness of breath, particularly on exertion. […] Surveillance of exposed workers with respiratory questionnaires, spirometry, and chest x-rays is recommended. […] As part of its National Emphasis Program on Silica, OSHA recommends that employers medically monitor all workers who may be exposed to silica dust levels at or above one-half the PEL. […] Although early treatment is generally supportive care, additional treatment options may be used to aid patient comfort and improve quality of life. […] Patients with airway obstruction may be treated empirically with bronchodilators and inhaled corticosteroids.

• #9 Silicosis Treatment | National Jewish Health

  https://www.nationaljewish.org/conditions/silicosis/treatment

  There is no cure for silicosis and no medications that can reverse the lung damage that has been done. This means that reducing and controlling exposure to silica dust is the only effective defense against silica-related lung disease. […] If you have been exposed to silica dust in your job, its important to be checked regularly by your health care provider. The earlier a diagnosis of silicosis can be made, the more helpful it can be. […] Treatment will be specific to your symptoms, so it will vary for each individual. Silicosis treatment is supportive and includes: […] Timely treatment of respiratory infections. Silicosis makes you more susceptible to infections, so its important that you watch for them and see your doctor right away if one develops. […] Smoking cessation. If you are a smoker, one of the most important things you can do to reduce silicosis symptoms is to quit smoking. Smoking damages your lungs, and aggravates the effects of silicosis. Avoid secondhand smoke and areas with a lot of dust. […] Lung transplant may be considered in some cases.

• #10 Silicosis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/22622-silicosis

  If you work in a silica-related industry, you should have regular check-ups to make sure youre healthy. If you experience any coughing or trouble breathing, see your provider. If youve been diagnosed with silicosis, and you have new signs or symptoms that concern you (such as fever, worsened breathing or unintended weight loss), contact your healthcare provider.

• #11 Silicosis Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/diseases-conditions/silicosis

  Silicosis is a lung disease caused by breathing in (inhaling) silica dust. […] There is no specific treatment for silicosis. Removing the source of silica exposure is important to prevent the disease from getting worse. Supportive treatment includes cough medicine, bronchodilators, and oxygen if needed. Antibiotics are prescribed for respiratory infections as needed. […] People with silicosis are at high risk for developing TB. Silica is believed to interfere with the body’s immune response to the bacteria that cause TB. […] Contact your provider if you suspect that you have been exposed to silica at work and you have breathing problems. […] If you’ve been diagnosed with silicosis, call your provider right away if you develop a cough, shortness of breath, fever, or other signs of a lung infection, especially if you think you have the flu. […] If you work in a high-risk occupation or have a high-risk hobby, always wear a dust mask and do not smoke.

• #12 Silicosis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/22622-silicosis

  If you work in a job around crystalline silica, you can breathe in dust that will cause lung damage. You can help to prevent silicosis if you use protective equipment. […] You cant cure or reverse silicosis, but your providers can treat it. […] You can only manage silicosis. You cant cure silicosis. Some tips for managing silicosis include: Quit smoking or using tobacco products. Use personal protective equipment or change jobs. Use a bronchodilator to improve airflow. Use supplemental oxygen if necessary. […] If you have silicosis, you should: Quit smoking and using tobacco products. Avoid other lung irritants like secondhand smoke and other air pollutants. Get all of the vaccines your provider recommends. Use the correct personal protective equipment, such as N95 masks or respirators, if you continue to work in a place with silica dust. Regular dust masks or face coverings arent enough. Follow proper procedure for working in a place with silica dust, including ventilation and using wetness to keep the dust down.

• #13 Silicosis and Crystalline Silica Exposure: What Physicians Need to Know

  https://www.health.ny.gov/environmental/investigations/silicosis/providerfact.htm

  Discuss prevention methods with your patient, and/or refer your patient to the New York State Occupational Health Clinic Network. […] Encourage patients to use all safety and exposure controls at their worksite, as well as appropriately maintained, approved, and fitted respirators. […] Observe for early signs and symptoms of respiratory disease. Provide medical monitoring and emphasize the importance of routine medical exams. […] Recommend smoking cessation programs. 1-866-NY-QUITS […] Urge patients to not bring dust home. This can be accomplished by changing into clean clothes and shoes, and if possible, showering prior to leaving their worksite. They should use on-site laundering services if available; if not, bag and wash work clothes separately from the household laundry. […] Emphasize good hygiene before eating. Instruct patients to wash their hands and face before eating and to not eat in their work areas.

• #14 Silicosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK594245/

  In individuals exposed to silica, diagnosing silicosis early and counseling patients on avoiding further RCS exposure and smoking cessation is essential to disease management. […] A coordinated effort of primary care practitioners, pulmonologists, nursing staff, occupational health specialists, and transplant surgeons will lead to the best patient outcomes. […] Nursing staff members are a valuable part of the healthcare team, as they often spend the most time in close contact with the patient and frequently form interpersonal relationships with them. […] Reassurance and gentle encouragement to reinforce essential lifestyle changes can immensely impact patients lives. […] Occupational health nurses are specifically beneficial, as they are trained to provide education on risk factors and prevention strategies at worksites.

• #15 Silicosis: Symptoms, Causes, Diagnosis, Treatment, Prevention

  https://www.webmd.com/lung/what-is-silicosis

  Silicosis is a lung disease. It usually happens in jobs where you breathe in dust that contains silica. […] There’s no cure for silicosis right now. Treatments can help you manage your symptoms. […] One major lifestyle change can help you manage this disease: Stop smoking: It’s dangerous if you have silicosis. It makes your lung damage even worse. Get help to quit. Avoid secondhand smoke and areas with a lot of dust, air pollution, and allergens if you can. […] The simplest steps include: Limit the time you’re exposed to silica. Wear a mask or other protective clothing while you work around it. Your employer is required to provide proper safety equipment. […] Other ways to prevent silicosis on the job: Use blasting cabinets or proper ventilation. Use wet methods to cut, chip, or grind materials. Swap blasting material that contains silica for other types. Use respirators that protect you from inhaling silica. Don’t eat or drink near silica dust. Wash your hands and face before you eat. Shower and change clothes after work.

• #16 Take a Breather: How to Manage Chronic Silicosis | UEW Health

  https://uewhealth.com/take-breather-manage-chronic-silicosis/

  Chest physical therapy has been known to help clear mucus and fluid from the lungs, making breathing easier and more manageable. […] Too much mucus and fluid in the lungs can also be a great breeding ground for bacteria. […] Exercise, in combination with the other three steps, is one of the best ways to keep your lungs clear and healthy. […] If you have been diagnosed with chronic silicosis and are interested in free home health care, give us a call today at (800) 314-2383.

• #17 Silicosis – Pulmonary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/pulmonary-disorders/environmental-and-occupational-pulmonary-diseases/silicosis

  Silicosis is caused by inhalation of respirable crystalline silica dust and is characterized by nodular pulmonary fibrosis. The cornerstone of treatment is supportive care and, for severe cases, lung transplantation. […] For chronic silicosis, symptomatic treatment (eg, bronchodilators and inhaled corticosteroids) is recommended. […] There are no proven, specific treatments for chronic silicosis. Treatment is primarily supportive. […] Patients with airway obstruction may benefit from bronchodilators and inhaled corticosteroids. Patients should be monitored and treated for hypoxemia. […] Pulmonary rehabilitation may help patients carry out activities of daily living. […] Patients who develop end-stage lung disease may be eligible for lung transplantation. […] Treatment of latent TB infection is recommended in patients with silicosis. […] Infections, including tuberculosis, should be treated promptly.

• #18 Take a Breather: How to Manage Chronic Silicosis | UEW Health

  https://uewhealth.com/take-breather-manage-chronic-silicosis/

  Chest physical therapy has been known to help clear mucus and fluid from the lungs, making breathing easier and more manageable. […] Too much mucus and fluid in the lungs can also be a great breeding ground for bacteria. […] Exercise, in combination with the other three steps, is one of the best ways to keep your lungs clear and healthy. […] If you have been diagnosed with chronic silicosis and are interested in free home health care, give us a call today at (800) 314-2383.

• #19 Treating and Managing Silicosis | American Lung Association

  https://www.lung.org/lung-health-diseases/lung-disease-lookup/silicosis/treating-and-managing

  There is no cure for silicosis and once the damage is done it cannot be reversed. Treatment is focused on slowing down the progression of the disease and relieving symptoms. Avoiding further exposure to silica and other irritants such as cigarette smoke is crucial. […] To keep the disease from getting worse, all silicosis patients need to eliminate any more exposure to silica. Other lung irritants, such as indoor and outdoor air pollution, allergens and smoke, should also be avoided. […] Your doctor can help manage your symptoms, but you can also take steps to keep yourself healthy by doing the following: Maintain weight and nutrition with a well-balanced diet. Stay as active as you can by exercising regularly but be careful not to overexert yourself. Prevent respiratory infections that can make your lungs worse. Get vaccinated against the flu every year, and pneumococcal pneumonia as recommended by your doctor. Be vigilant about watching for the development of TB or other infections and see your doctor immediately if one develops. Have a plan to manage flare-ups of the disease.

• #20 Silicosis

  https://www.nhs.uk/conditions/silicosis/

  There’s no cure for silicosis because the lung damage can’t be reversed. Treatment aims to relieve symptoms and improve quality of life. […] You may be offered long-term home oxygen therapy if you’re having difficulty breathing and have low levels of oxygen in your blood. […] Bronchodilator medicines may also be prescribed to widen your airways and make breathing easier. […] You’ll be given a course of antibiotics if you develop a bacterial chest infection. […] In very severe cases, a lung transplant may be an option, although there are strict health requirements to meet before this will be considered.

• #21 Silicosis – Pulmonary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/pulmonary-disorders/environmental-and-occupational-pulmonary-diseases/silicosis

  Silicosis is caused by inhalation of respirable crystalline silica dust and is characterized by nodular pulmonary fibrosis. The cornerstone of treatment is supportive care and, for severe cases, lung transplantation. […] For chronic silicosis, symptomatic treatment (eg, bronchodilators and inhaled corticosteroids) is recommended. […] There are no proven, specific treatments for chronic silicosis. Treatment is primarily supportive. […] Patients with airway obstruction may benefit from bronchodilators and inhaled corticosteroids. Patients should be monitored and treated for hypoxemia. […] Pulmonary rehabilitation may help patients carry out activities of daily living. […] Patients who develop end-stage lung disease may be eligible for lung transplantation. […] Treatment of latent TB infection is recommended in patients with silicosis. […] Infections, including tuberculosis, should be treated promptly.

• #22 Silicosis

  https://www.nhs.uk/conditions/silicosis/

  There’s no cure for silicosis because the lung damage can’t be reversed. Treatment aims to relieve symptoms and improve quality of life. […] You may be offered long-term home oxygen therapy if you’re having difficulty breathing and have low levels of oxygen in your blood. […] Bronchodilator medicines may also be prescribed to widen your airways and make breathing easier. […] You’ll be given a course of antibiotics if you develop a bacterial chest infection. […] In very severe cases, a lung transplant may be an option, although there are strict health requirements to meet before this will be considered.

• #23 Silicosis – Pulmonary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/pulmonary-disorders/environmental-and-occupational-pulmonary-diseases/silicosis

  Silicosis is caused by inhalation of respirable crystalline silica dust and is characterized by nodular pulmonary fibrosis. The cornerstone of treatment is supportive care and, for severe cases, lung transplantation. […] For chronic silicosis, symptomatic treatment (eg, bronchodilators and inhaled corticosteroids) is recommended. […] There are no proven, specific treatments for chronic silicosis. Treatment is primarily supportive. […] Patients with airway obstruction may benefit from bronchodilators and inhaled corticosteroids. Patients should be monitored and treated for hypoxemia. […] Pulmonary rehabilitation may help patients carry out activities of daily living. […] Patients who develop end-stage lung disease may be eligible for lung transplantation. […] Treatment of latent TB infection is recommended in patients with silicosis. […] Infections, including tuberculosis, should be treated promptly.

• #24 Silicosis | Health & Human Services

  https://hhs.iowa.gov/epi-manual-guide-surveillance-investigation-and-reporting/environmental-disease/silicosis

  Silicosis is an irreversible but preventable disease, and is the illness most closely associated with occupational exposure to silica dust. […] The symptoms of silicosis are a cough, with or without sputum, chest tightness, and shortness of breath, particularly on exertion. […] Surveillance of exposed workers with respiratory questionnaires, spirometry, and chest x-rays is recommended. […] As part of its National Emphasis Program on Silica, OSHA recommends that employers medically monitor all workers who may be exposed to silica dust levels at or above one-half the PEL. […] Although early treatment is generally supportive care, additional treatment options may be used to aid patient comfort and improve quality of life. […] Patients with airway obstruction may be treated empirically with bronchodilators and inhaled corticosteroids.

• #25 Silicosis : MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000134.htm

  Silicosis is a lung disease caused by breathing in (inhaling) silica dust. […] There is no specific treatment for silicosis. Removing the source of silica exposure is important to prevent the disease from getting worse. Supportive treatment includes cough medicine, bronchodilators, and oxygen if needed. Antibiotics are prescribed for respiratory infections as needed. […] People with silicosis are at high risk for developing TB. Silica is believed to interfere with the body’s immune response to the bacteria that cause TB. […] Joining a support group where you can meet other people with silicosis or related diseases can help you understand your disease and adapt to its treatments. […] Contact your provider if you suspect that you have been exposed to silica at work and you have breathing problems. […] If you work in a high-risk occupation or have a high-risk hobby, always wear a dust mask and do not smoke. You might also want to use other protection recommended by OSHA, such as a respirator.

• #26 Silicosis

  https://www.nhs.uk/conditions/silicosis/

  There’s no cure for silicosis because the lung damage can’t be reversed. Treatment aims to relieve symptoms and improve quality of life. […] You may be offered long-term home oxygen therapy if you’re having difficulty breathing and have low levels of oxygen in your blood. […] Bronchodilator medicines may also be prescribed to widen your airways and make breathing easier. […] You’ll be given a course of antibiotics if you develop a bacterial chest infection. […] In very severe cases, a lung transplant may be an option, although there are strict health requirements to meet before this will be considered.

• #27 Silicosis Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/302027-treatment

  Polyvinylpyridine-N-oxide (PVPNO) has been shown to decrease the potential for silica toxicity in animal models. It coats the surface of silica particles and decreases their potential for generating reactive oxygen species, thus limiting DNA damage. […] However, use of PVPNO is limited by liver and renal toxicity demonstrated in animal studies. […] Nintedanib, an antifibrotic therapy used in idiopathic pulmonary fibrosis (IPF), have been studied in animal models, but it has yet to be studied in human trials. […] The Nintedanib in Progressive Pneumoconiosis Study (NiPPS), a prospective clinical pilot study evaluating occupational progressive pneumoconiosis (silicosis, coal pneumoconiosis, and asbestosis) with nintedanib 150 mg twice daily for 3 years, has not yet begun recruiting but has an expected start date of February 2020.

• #28

• #29 Silicosis

  https://www.nhs.uk/conditions/silicosis/

  There’s no cure for silicosis because the lung damage can’t be reversed. Treatment aims to relieve symptoms and improve quality of life. […] You may be offered long-term home oxygen therapy if you’re having difficulty breathing and have low levels of oxygen in your blood. […] Bronchodilator medicines may also be prescribed to widen your airways and make breathing easier. […] You’ll be given a course of antibiotics if you develop a bacterial chest infection. […] In very severe cases, a lung transplant may be an option, although there are strict health requirements to meet before this will be considered.

• #30 Best Silicosis Treatment in Delhi, India | Symptoms, Causes & Types | Max Hospital

  https://www.maxhealthcare.in/our-specialities/pulmonology/conditions-treatments/silicosis

  Supplemental oxygen therapy is essential for patients with advanced silicosis who experience severe respiratory impairment and inadequate oxygen levels in the blood. This therapy aims to optimise blood oxygenation, relieve symptoms of hypoxia (such as fatigue and cyanosis), and improve overall functional capacity. […] Pulmonary rehabilitation programs are integral components of silicosis management, designed to enhance lung function and overall physical health. These structured programs include supervised exercise training sessions that focus on strengthening respiratory muscles, improving cardiovascular endurance, and enhancing functional capacity. […] Continuous medical monitoring is essential in silicosis management to assess disease progression, monitor silicosis treatment effectiveness, and adjust management strategies accordingly.

• #31 Best Silicosis Treatment in Delhi, India | Symptoms, Causes & Types | Max Hospital

  https://www.maxhealthcare.in/our-specialities/pulmonology/conditions-treatments/silicosis

  Supplemental oxygen therapy is essential for patients with advanced silicosis who experience severe respiratory impairment and inadequate oxygen levels in the blood. This therapy aims to optimise blood oxygenation, relieve symptoms of hypoxia (such as fatigue and cyanosis), and improve overall functional capacity. […] Pulmonary rehabilitation programs are integral components of silicosis management, designed to enhance lung function and overall physical health. These structured programs include supervised exercise training sessions that focus on strengthening respiratory muscles, improving cardiovascular endurance, and enhancing functional capacity. […] Continuous medical monitoring is essential in silicosis management to assess disease progression, monitor silicosis treatment effectiveness, and adjust management strategies accordingly.

• #32 Best Silicosis Treatment in Delhi, India | Symptoms, Causes & Types | Max Hospital

  https://www.maxhealthcare.in/our-specialities/pulmonology/conditions-treatments/silicosis

  Supplemental oxygen therapy is essential for patients with advanced silicosis who experience severe respiratory impairment and inadequate oxygen levels in the blood. This therapy aims to optimise blood oxygenation, relieve symptoms of hypoxia (such as fatigue and cyanosis), and improve overall functional capacity. […] Pulmonary rehabilitation programs are integral components of silicosis management, designed to enhance lung function and overall physical health. These structured programs include supervised exercise training sessions that focus on strengthening respiratory muscles, improving cardiovascular endurance, and enhancing functional capacity. […] Continuous medical monitoring is essential in silicosis management to assess disease progression, monitor silicosis treatment effectiveness, and adjust management strategies accordingly.

• #33 Silicosis – Pulmonary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/pulmonary-disorders/environmental-and-occupational-pulmonary-diseases/silicosis

  Silicosis is caused by inhalation of respirable crystalline silica dust and is characterized by nodular pulmonary fibrosis. The cornerstone of treatment is supportive care and, for severe cases, lung transplantation. […] For chronic silicosis, symptomatic treatment (eg, bronchodilators and inhaled corticosteroids) is recommended. […] There are no proven, specific treatments for chronic silicosis. Treatment is primarily supportive. […] Patients with airway obstruction may benefit from bronchodilators and inhaled corticosteroids. Patients should be monitored and treated for hypoxemia. […] Pulmonary rehabilitation may help patients carry out activities of daily living. […] Patients who develop end-stage lung disease may be eligible for lung transplantation. […] Treatment of latent TB infection is recommended in patients with silicosis. […] Infections, including tuberculosis, should be treated promptly.

• #34 Take a Breather: How to Manage Chronic Silicosis | UEW Health

  https://uewhealth.com/take-breather-manage-chronic-silicosis/

  Chest physical therapy has been known to help clear mucus and fluid from the lungs, making breathing easier and more manageable. […] Too much mucus and fluid in the lungs can also be a great breeding ground for bacteria. […] Exercise, in combination with the other three steps, is one of the best ways to keep your lungs clear and healthy. […] If you have been diagnosed with chronic silicosis and are interested in free home health care, give us a call today at (800) 314-2383.

• #35 Silicosis Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/302027-treatment

  Consulting a pulmonologist is appropriate for the evaluation of lung nodules, assessment of pulmonary function, and evaluation of disability, as well as treatment of mycobacterial disease and complications of advanced silicosis. […] Treatment for silicosis-associated conditions (eg, mycobacterial infection, chronic obstructive pulmonary disease, lung cancer, autoimmune disorders, and chronic kidney disease) are principally similar to that of patients without silicosis. […] Treatment strategies targeting the inflammatory pathway of silicosis have been investigated, however, consistently effective therapies yet to be developed, and no cure currently exists. […] Whole-lung lavage has previously been used for silicoproteinosis. Although the presence of dust particles, macrophages, and cytokines on bronchoalveolar lavage analyses decrease with whole-lung lavage, long-term outcomes, including mortality and pulmonary function parameters, have not demonstrated sustained improvement.

• #36 Silicosis Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/302027-treatment

  Cell-based therapy, including bone marrow-derived mononuclear cells and mesenchymal cell transplantation, are currently undergoing trials in humans. […] Lung transplantation remains the only treatment option for end-stage silicosis. However, based on available data, patients with silicosis who underwent lung transplantation (4.9%) showed a nonstatistically significant survival advantage (hazard ratio: 0.6) compared to those undergoing the procedure for idiopathic pulmonary fibrosis (IPF). […] Primary prevention of silicosis through exposure control is important, because no effective medical treatment exists for this disease, which continues to progress even after a person is removed from further exposure. […] To achieve this, a sustained effort must be made to increase awareness of silicosis.

• #37 Silicosis | Conditions | UCSF Health

  https://www.ucsfhealth.org/conditions/silicosis

  Silicosis is a lung disease caused by the inhalation of crystalline silica dust. […] UCSF provides comprehensive evaluations and care for work-related lung diseases, such as silicosis. […] Although silicosis currently has no cure, treatments can relieve symptoms and prevent complications. […] Unfortunately, there is no cure for silicosis. However, there is a variety of treatments available to help manage symptoms and prevent complications associated with the disease. […] In severe cases, lung transplant may be an option for some patients with silicosis.

• #38 Silicosis Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/302027-treatment

  Cell-based therapy, including bone marrow-derived mononuclear cells and mesenchymal cell transplantation, are currently undergoing trials in humans. […] Lung transplantation remains the only treatment option for end-stage silicosis. However, based on available data, patients with silicosis who underwent lung transplantation (4.9%) showed a nonstatistically significant survival advantage (hazard ratio: 0.6) compared to those undergoing the procedure for idiopathic pulmonary fibrosis (IPF). […] Primary prevention of silicosis through exposure control is important, because no effective medical treatment exists for this disease, which continues to progress even after a person is removed from further exposure. […] To achieve this, a sustained effort must be made to increase awareness of silicosis.

• #39 Silicosis Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/302027-treatment

  Cell-based therapy, including bone marrow-derived mononuclear cells and mesenchymal cell transplantation, are currently undergoing trials in humans. […] Lung transplantation remains the only treatment option for end-stage silicosis. However, based on available data, patients with silicosis who underwent lung transplantation (4.9%) showed a nonstatistically significant survival advantage (hazard ratio: 0.6) compared to those undergoing the procedure for idiopathic pulmonary fibrosis (IPF). […] Primary prevention of silicosis through exposure control is important, because no effective medical treatment exists for this disease, which continues to progress even after a person is removed from further exposure. […] To achieve this, a sustained effort must be made to increase awareness of silicosis.

• #40 Silicosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK594245/

  Silicosis is a preventable disease with significant morbidity and mortality that has no cure. Education on prevention, screening, timely diagnosis, avoidance of exacerbating factors, and treatment of complications is imperative. […] This activity reviews the etiology, epidemiology, pathogenesis, pathophysiology, clinical evaluation, and management of silicosis and highlights the role of the interprofessional team in caring for patients with this occupational pneumoconiosis. […] There is currently no effective treatment for silicosis. Most interventions are supportive and consist of supplemental oxygen in those with hypoxia, recommended vaccinations, prompt treatment of infection, and pulmonary rehabilitation. […] Although silicosis is currently untreatable, it is undoubtedly preventable. Primary prevention by controlling RCS exposure is critical.

• #41 Silicosis | Health & Human Services

  https://hhs.iowa.gov/epi-manual-guide-surveillance-investigation-and-reporting/environmental-disease/silicosis

  Management of tuberculosis is the same as for other patients with tuberculosis except that longer courses of drug therapy are usually recommended because relapse is more common in patients with silicotuberculosis. […] The most effective preventive interventions occur at an industrial rather than clinical level and include dust suppression, process isolation, ventilation, and use of nonsilica-containing abrasives. […] Physicians must be alert to the risk of TB and nontuberculous mycobacterial infections in silica-exposed patients, especially miners.

• #42 Silicosis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/22622-silicosis

  If you work in a job around crystalline silica, you can breathe in dust that will cause lung damage. You can help to prevent silicosis if you use protective equipment. […] You cant cure or reverse silicosis, but your providers can treat it. […] You can only manage silicosis. You cant cure silicosis. Some tips for managing silicosis include: Quit smoking or using tobacco products. Use personal protective equipment or change jobs. Use a bronchodilator to improve airflow. Use supplemental oxygen if necessary. […] If you have silicosis, you should: Quit smoking and using tobacco products. Avoid other lung irritants like secondhand smoke and other air pollutants. Get all of the vaccines your provider recommends. Use the correct personal protective equipment, such as N95 masks or respirators, if you continue to work in a place with silica dust. Regular dust masks or face coverings arent enough. Follow proper procedure for working in a place with silica dust, including ventilation and using wetness to keep the dust down.

• #43 Silicosis Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/302027-treatment

  Recommendations by the National Institute for Occupational Safety and Health (NIOSH) to reduce exposures to respirable crystalline silica in the workplace and to prevent silicosis and deaths in construction workers are outlined below. […] Recognize when silica dust may be generated and plan ahead to eliminate or control the dust at the source. Awareness and planning are keys to prevention of silicosis. […] The respiratory protection program should be evaluated regularly by the employer. […] Provide periodic medical examinations for all workers who may be exposed to respirable crystalline silica. […] Report all cases of silicosis to State health departments and OSHA.

• #44 Silicosis | Health & Human Services

  https://hhs.iowa.gov/epi-manual-guide-surveillance-investigation-and-reporting/environmental-disease/silicosis

  Silicosis is an irreversible but preventable disease, and is the illness most closely associated with occupational exposure to silica dust. […] The symptoms of silicosis are a cough, with or without sputum, chest tightness, and shortness of breath, particularly on exertion. […] Surveillance of exposed workers with respiratory questionnaires, spirometry, and chest x-rays is recommended. […] As part of its National Emphasis Program on Silica, OSHA recommends that employers medically monitor all workers who may be exposed to silica dust levels at or above one-half the PEL. […] Although early treatment is generally supportive care, additional treatment options may be used to aid patient comfort and improve quality of life. […] Patients with airway obstruction may be treated empirically with bronchodilators and inhaled corticosteroids.

• #45 Center of Excellence for Silicosis & Its Prevention Program

  https://www.nationaljewish.org/directory/silicosis-prevention

  Silicosis is a scarring disease of the lung caused by inhaling fine particles of crystalline silica dust. Chronic dry cough and shortness of breath are early symptoms of disease. Silicosis can worsen over time, especially with continued dust exposure. The disease typically takes 5-20 years after first exposure to appear. […] If workers are diagnosed with silicosis, they must be removed from exposure to minimize the risk for progression of fibrotic lung disease and for the other diseases associated with silica exposure. […] For workers: Diagnosis of silica-related diseases by board-certified occupational lung specialists. Treatment of the complications of silicosis. Medical guidance for removal from dust exposure. […] Conditions Treated Health Information: Silicosis. Other diseases associated with silica exposure including: Chronic Obstructive Pulmonary Disease (COPD)/Emphysema, Tuberculosis (TB) and other lung infections, Lung cancer, Kidney disease, Autoimmune diseases (such as rheumatoid arthritis). […] At National Jewish Health, we can offer employers: OSHA-compliant medical screening and surveillance for early disease. Occupational Medicine Medical Surveillance Program. Occupational Medicine Respirator Fit Program.

• #46 Silicosis | Health & Human Services

  https://hhs.iowa.gov/epi-manual-guide-surveillance-investigation-and-reporting/environmental-disease/silicosis

  Silicosis is an irreversible but preventable disease, and is the illness most closely associated with occupational exposure to silica dust. […] The symptoms of silicosis are a cough, with or without sputum, chest tightness, and shortness of breath, particularly on exertion. […] Surveillance of exposed workers with respiratory questionnaires, spirometry, and chest x-rays is recommended. […] As part of its National Emphasis Program on Silica, OSHA recommends that employers medically monitor all workers who may be exposed to silica dust levels at or above one-half the PEL. […] Although early treatment is generally supportive care, additional treatment options may be used to aid patient comfort and improve quality of life. […] Patients with airway obstruction may be treated empirically with bronchodilators and inhaled corticosteroids.

• #47 Silicosis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/22622-silicosis

  If you work in a job around crystalline silica, you can breathe in dust that will cause lung damage. You can help to prevent silicosis if you use protective equipment. […] You cant cure or reverse silicosis, but your providers can treat it. […] You can only manage silicosis. You cant cure silicosis. Some tips for managing silicosis include: Quit smoking or using tobacco products. Use personal protective equipment or change jobs. Use a bronchodilator to improve airflow. Use supplemental oxygen if necessary. […] If you have silicosis, you should: Quit smoking and using tobacco products. Avoid other lung irritants like secondhand smoke and other air pollutants. Get all of the vaccines your provider recommends. Use the correct personal protective equipment, such as N95 masks or respirators, if you continue to work in a place with silica dust. Regular dust masks or face coverings arent enough. Follow proper procedure for working in a place with silica dust, including ventilation and using wetness to keep the dust down.

• #48 Treating and Managing Silicosis | American Lung Association

  https://www.lung.org/lung-health-diseases/lung-disease-lookup/silicosis/treating-and-managing

  There is no cure for silicosis and once the damage is done it cannot be reversed. Treatment is focused on slowing down the progression of the disease and relieving symptoms. Avoiding further exposure to silica and other irritants such as cigarette smoke is crucial. […] To keep the disease from getting worse, all silicosis patients need to eliminate any more exposure to silica. Other lung irritants, such as indoor and outdoor air pollution, allergens and smoke, should also be avoided. […] Your doctor can help manage your symptoms, but you can also take steps to keep yourself healthy by doing the following: Maintain weight and nutrition with a well-balanced diet. Stay as active as you can by exercising regularly but be careful not to overexert yourself. Prevent respiratory infections that can make your lungs worse. Get vaccinated against the flu every year, and pneumococcal pneumonia as recommended by your doctor. Be vigilant about watching for the development of TB or other infections and see your doctor immediately if one develops. Have a plan to manage flare-ups of the disease.

• #49 Silicosis

  https://www.svhlunghealth.com.au/conditions/silicosis

  Get your regular vaccinations these help to prevent lung disease like cold and flu […] Have regular tests to check your lung function to detect any symptoms of lung disease […] If you smoke, quit smoking further damages your lungs, so phone 13QUIT to get started […] Learn about your disease be informed, so you know how to prevent your disease from getting worse […] Limit your exposure to silicosis you may need to consider changing jobs […] Maintain a healthy lifestyle speak to your doctor about developing a healthy diet and exercise plan […] Stay away from known lung irritants including air pollution and cigarette smoke.

• #50 Silicosis Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/diseases-conditions/silicosis

  Silicosis is a lung disease caused by breathing in (inhaling) silica dust. […] There is no specific treatment for silicosis. Removing the source of silica exposure is important to prevent the disease from getting worse. Supportive treatment includes cough medicine, bronchodilators, and oxygen if needed. Antibiotics are prescribed for respiratory infections as needed. […] People with silicosis are at high risk for developing TB. Silica is believed to interfere with the body’s immune response to the bacteria that cause TB. […] Contact your provider if you suspect that you have been exposed to silica at work and you have breathing problems. […] If you’ve been diagnosed with silicosis, call your provider right away if you develop a cough, shortness of breath, fever, or other signs of a lung infection, especially if you think you have the flu. […] If you work in a high-risk occupation or have a high-risk hobby, always wear a dust mask and do not smoke.

• #51 Silicosis – Pulmonary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/pulmonary-disorders/environmental-and-occupational-pulmonary-diseases/silicosis

  Silicosis is caused by inhalation of respirable crystalline silica dust and is characterized by nodular pulmonary fibrosis. The cornerstone of treatment is supportive care and, for severe cases, lung transplantation. […] For chronic silicosis, symptomatic treatment (eg, bronchodilators and inhaled corticosteroids) is recommended. […] There are no proven, specific treatments for chronic silicosis. Treatment is primarily supportive. […] Patients with airway obstruction may benefit from bronchodilators and inhaled corticosteroids. Patients should be monitored and treated for hypoxemia. […] Pulmonary rehabilitation may help patients carry out activities of daily living. […] Patients who develop end-stage lung disease may be eligible for lung transplantation. […] Treatment of latent TB infection is recommended in patients with silicosis. […] Infections, including tuberculosis, should be treated promptly.

• #52 Guidelines for the Diagnosis and Monitoring of Silicosis | Archivos de Bronconeumología

  https://archbronconeumol.org/en-guidelines-for-diagnosis-monitoring-silicosis-articulo-S1579212914003759

  When silicosis has been diagnosed, all exposure to silica must be avoided to prevent disease progression. Any tuberculosis infection must be detected and treated according to standard procedures. […] The first medical prescription when silicosis is diagnosed is to cease exposure. If the patient is an active worker, this must be reported to the occupational risk prevention department and the individual should be moved to a position without risk of exposure. If such a position is unavailable, the patient must be considered unfit for their current job. […] A diagnosis of silicosis has a profound impact on the social and working life of a patient, since, unlike other diseases, it rules out any chance of continuing to work in jobs with a risk of silica exposure irrespective of functional involvement, so for this reason the diagnosis must be robust.

• #53

  https://bpac.org.nz/2023/silicosis.aspx

  Guidance regarding patient follow-up and any symptom management is provided by ACC and respiratory physicians as part of the Accelerated Silicosis Assessment Pathway. […] Effective intervention options for patients with accelerated silicosis are limited. Management usually involves symptomatic and supportive interventions to protect cardiopulmonary function (e.g. inhaled bronchodilators), maintaining a healthy body weight and undergoing pulmonary rehabilitation. […] Some patients diagnosed with accelerated silicosis may require psychological support. The reduction in quality of life, e.g. loss of physical ability to carry out normal activities, loss of career, financial concerns and the impact of potentially receiving a terminal diagnosis will likely have a significant effect on a persons mental wellbeing and relationships.

• #54 Silicosis – Lung Foundation Australia

  https://lungfoundation.com.au/patients-carers/conditions/occupational-lung-disease/silicosis/

  Silicosis is a complex condition and there are many decisions to be made, as well as emotional and practical concerns. […] Our nurse can provide free telephone-based information and support around understanding and living with silicosis, as well as provide guidance about relevant support services. […] This free telephone-based service can help you to navigate the practical and emotional impact of living with silicosis. […] Our online silicosis peer support groups can help those impacted by silicosis connect to others Australia-wide to share their experiences and help each other through the unique challenges. […] Health monitoring is important, particularly as a means of identifying workers with silicosis who often have no symptoms, and providing appropriate management. […] There is currently no treatment to reverse silicosis. However, there are management and treatment options available that may slow progression of the disease and may also help to reduce your symptoms.

• #55 Silicosis : MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000134.htm

  Silicosis is a lung disease caused by breathing in (inhaling) silica dust. […] There is no specific treatment for silicosis. Removing the source of silica exposure is important to prevent the disease from getting worse. Supportive treatment includes cough medicine, bronchodilators, and oxygen if needed. Antibiotics are prescribed for respiratory infections as needed. […] People with silicosis are at high risk for developing TB. Silica is believed to interfere with the body’s immune response to the bacteria that cause TB. […] Joining a support group where you can meet other people with silicosis or related diseases can help you understand your disease and adapt to its treatments. […] Contact your provider if you suspect that you have been exposed to silica at work and you have breathing problems. […] If you work in a high-risk occupation or have a high-risk hobby, always wear a dust mask and do not smoke. You might also want to use other protection recommended by OSHA, such as a respirator.

• #56 Silicosis | Healthify

  https://healthify.nz/health-a-z/s/silicosis

  Having enough protection from silica dust is the best way to prevent silicosis. Employers in any industry involved in working with silica should have reviewed their business and completed a risk assessment for silica exposure for their workers. […] Talk to your healthcare provider about making an ACC claim. Work and Income NZ may help you in finding options and benefits if you have to stop work.

• #57 Silicosis | Healthify

  https://healthify.nz/health-a-z/s/silicosis

  Silicosis is an irreversible chronic lung disease caused by breathing in too much crystalline silica dust found in some types of stone, rock, clay and sand. […] Common symptoms are ongoing cough, shortness of breath and tiredness. Silicosis is irreversible (can’t be cured) but treatment can help relieve symptoms. […] If you have silicosis, your lungs are already damaged. There are self-care measures to protect your lungs from further damage. Here are some examples: Stop further exposure to silica dust even if that means you have to stop working (you may be eligible for a benefit). […] Treatments aim to relieve your symptoms and check your progression. If you’re still exposed to silica dust, your healthcare provider or lung specialist doctor will advise you to stop any further exposure. Lung transplantation is the ultimate treatment for the most severe forms of silicosis.

• #58 Silicosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK594245/

  In individuals exposed to silica, diagnosing silicosis early and counseling patients on avoiding further RCS exposure and smoking cessation is essential to disease management. […] A coordinated effort of primary care practitioners, pulmonologists, nursing staff, occupational health specialists, and transplant surgeons will lead to the best patient outcomes. […] Nursing staff members are a valuable part of the healthcare team, as they often spend the most time in close contact with the patient and frequently form interpersonal relationships with them. […] Reassurance and gentle encouragement to reinforce essential lifestyle changes can immensely impact patients lives. […] Occupational health nurses are specifically beneficial, as they are trained to provide education on risk factors and prevention strategies at worksites.

• #59 Silicosis Treatment | Explore Treatment Options & Support

  https://silicosis.org.au/living-with-silicosis/silicosis-treatment-options/

  From coordinating care and managing symptoms to providing emotional support, each team member plays a vital role in helping you live well with silicosis. […] Clinical trials offer access to breakthrough treatments and medical innovations that are not yet widely available. […] While treatment is essential, so is managing daily life with silicosis. Simple changes to your lifestyle can improve lung health, reduce stress, and support your mental well-being. […] Lifestyle changes can improve lung health and well-being. Key changes include quitting smoking to reduce lung strain, eating a healthy diet to support the immune system, staying active to maintain lung strength, and prioritising mental health with support from family, friends, or mental health professionals.

• #60 Silicosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK594245/

  In individuals exposed to silica, diagnosing silicosis early and counseling patients on avoiding further RCS exposure and smoking cessation is essential to disease management. […] A coordinated effort of primary care practitioners, pulmonologists, nursing staff, occupational health specialists, and transplant surgeons will lead to the best patient outcomes. […] Nursing staff members are a valuable part of the healthcare team, as they often spend the most time in close contact with the patient and frequently form interpersonal relationships with them. […] Reassurance and gentle encouragement to reinforce essential lifestyle changes can immensely impact patients lives. […] Occupational health nurses are specifically beneficial, as they are trained to provide education on risk factors and prevention strategies at worksites.

• #61 A rapid point of care CC16 kit for screening of occupational silica dust exposed workers for early detection of silicosis/silico-tuberculosis | Scientific Reports

  https://www.nature.com/articles/s41598-021-02392-y

  This kit is intended for periodic screening (preferably annual or bi-annual if silica content of the inhaled dust is high) among silica dust exposed workers for early diagnosis and prevention/control of silicosis and to be managed by the network of peripheral health care workers of the entire country. […] The purpose of this paper is to demonstrate the performance evaluation of LFA in comparison with ELISA to validate the developed assay. The purpose of this manuscript is to provide an assay for the screening of the silica dust exposed workers. The utility of this screening assay is to identify the individuals for further medical interventions. The individuals exhibiting 2 or less number of bands on LFA (CC16 concentration9 ng/ml) are may be in the early stages of silicosis and should be advised thorough medical examination such as spirometry, chest X-ray or CT scan etc. for confirmation. […] Hence, this assay would be useful for early detection of silicosis for various purposes such as notification to the local authority, secondary prevention and financial compensation as per guidelines of the country.

• #62 A rapid point of care CC16 kit for screening of occupational silica dust exposed workers for early detection of silicosis/silico-tuberculosis | Scientific Reports

  https://www.nature.com/articles/s41598-021-02392-y

  Silicosis is an irreversible, incurable and progressive occupational disease caused by prolonged exposure to crystalline-silica dust while working in the relevant industries. […] Early detection and necessary intervention (secondary prevention) could be a realistic possible control strategy for controlling silicosis as no effective treatment is available to stop and/or reverse the pathological process. […] A suitable biomarker is urgently required for early detection of silicosis among silica dust exposed workers. Early detection using a suitable bio-marker will prevent generating moderate and advanced silicosis and its associated co-morbidities (silico-tuberculosis, renal disease, stroke, heart disease, lung cancer etc.) by minimizing further dust exposure. […] A suitable biomarker for early suspicion of silicosis may be a useful screening tool for secondary prevention of silicosis and silico-tuberculosis to protect these vulnerable workers.

• #63 Silicosis Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/302027-treatment

  Polyvinylpyridine-N-oxide (PVPNO) has been shown to decrease the potential for silica toxicity in animal models. It coats the surface of silica particles and decreases their potential for generating reactive oxygen species, thus limiting DNA damage. […] However, use of PVPNO is limited by liver and renal toxicity demonstrated in animal studies. […] Nintedanib, an antifibrotic therapy used in idiopathic pulmonary fibrosis (IPF), have been studied in animal models, but it has yet to be studied in human trials. […] The Nintedanib in Progressive Pneumoconiosis Study (NiPPS), a prospective clinical pilot study evaluating occupational progressive pneumoconiosis (silicosis, coal pneumoconiosis, and asbestosis) with nintedanib 150 mg twice daily for 3 years, has not yet begun recruiting but has an expected start date of February 2020.

• #64 Silicosis Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/302027-treatment

  Cell-based therapy, including bone marrow-derived mononuclear cells and mesenchymal cell transplantation, are currently undergoing trials in humans. […] Lung transplantation remains the only treatment option for end-stage silicosis. However, based on available data, patients with silicosis who underwent lung transplantation (4.9%) showed a nonstatistically significant survival advantage (hazard ratio: 0.6) compared to those undergoing the procedure for idiopathic pulmonary fibrosis (IPF). […] Primary prevention of silicosis through exposure control is important, because no effective medical treatment exists for this disease, which continues to progress even after a person is removed from further exposure. […] To achieve this, a sustained effort must be made to increase awareness of silicosis.

• #65 Silicosis Treatment | Explore Treatment Options & Support

  https://silicosis.org.au/living-with-silicosis/silicosis-treatment-options/

  From coordinating care and managing symptoms to providing emotional support, each team member plays a vital role in helping you live well with silicosis. […] Clinical trials offer access to breakthrough treatments and medical innovations that are not yet widely available. […] While treatment is essential, so is managing daily life with silicosis. Simple changes to your lifestyle can improve lung health, reduce stress, and support your mental well-being. […] Lifestyle changes can improve lung health and well-being. Key changes include quitting smoking to reduce lung strain, eating a healthy diet to support the immune system, staying active to maintain lung strength, and prioritising mental health with support from family, friends, or mental health professionals.

• #66 Silicosis Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/302027-treatment

  Consulting a pulmonologist is appropriate for the evaluation of lung nodules, assessment of pulmonary function, and evaluation of disability, as well as treatment of mycobacterial disease and complications of advanced silicosis. […] Treatment for silicosis-associated conditions (eg, mycobacterial infection, chronic obstructive pulmonary disease, lung cancer, autoimmune disorders, and chronic kidney disease) are principally similar to that of patients without silicosis. […] Treatment strategies targeting the inflammatory pathway of silicosis have been investigated, however, consistently effective therapies yet to be developed, and no cure currently exists. […] Whole-lung lavage has previously been used for silicoproteinosis. Although the presence of dust particles, macrophages, and cytokines on bronchoalveolar lavage analyses decrease with whole-lung lavage, long-term outcomes, including mortality and pulmonary function parameters, have not demonstrated sustained improvement.

• #67 National Registry to fight silicosis and protect workers | Health Portfolio Ministers | Australian Government Department of Health and Aged Care

  https://www.health.gov.au/ministers/the-hon-ged-kearney-mp/media/national-registry-to-fight-silicosis-and-protect-workers

  The Australian Government has taken the next step in fighting deadly occupational respiratory diseases like silicosis by establishing Australia’s first National Occupational Respiratory Disease Registry. […] The National Registry will help eliminate preventable occupational respiratory diseases by supporting earlier detection, intervention and prevention. It will provide a better understanding of how widespread occupational respiratory diseases are, help reduce worker exposure, and improve the quality of life for the people affected and their families. […] The National Registry will record the type and extent of occupational respiratory diseases in Australia, with the reporting of silicosis to be mandatory. […] “No one should die because they’ve turned up to work. Establishing the National Registry will help Australia fight silicosis and other dust related diseases. […] “This registry will save lives. We’ll be able to identify the industries, occupations, job tasks and workplaces that are at risk, and use targeted early intervention and prevention activities to reduce worker exposure and disease.”

• #68 Implementation and Cost Analysis of a Novel Silicosis Case-Finding Program For Mine Workers in Rural Rwanda | Global Health: Science and Practice

  https://www.ghspjournal.org/content/12/2/e2300290

  A novel case-finding program for silicosis was developed and implemented for mine workers working in semi-industrial mines that included education about causes and protection, symptom screening for silicosis and TB, chest X-ray, spirometry, and screening for hypertension and diabetes. […] Occupational lung disease case-finding can be integrated with routine noncommunicable disease case-finding to reduce costs and improve comprehensive linkage to care. […] Silicosis is an incurable interstitial lung disease caused by the inhalation of respirable crystalline silica (i.e., silicon dioxide) particles. […] Because silicosis is currently incurable, education about the causes and health consequences of the disease was prioritized throughout the program. […] All mine workers were screened for hypertension and diabetes.

• #69 Silicosis – symptoms, treatments and causes | healthdirect

  https://www.healthdirect.gov.au/silicosis

  Silicosis is a serious chronic (ongoing) lung condition caused by silica dust. […] Silicosis can be prevented but there is currently no cure. […] There are some things you can do to help reduce complications and improve your quality of life: avoid further exposure to silica dust, quit smoking or vaping, eat well and stay active, or start exercising, keep your vaccinations, such as your annual flu jab, up to date. […] Your doctor might recommend treatments to help with your breathing, such as: an inhaler, anti-fibrotic medication (medicine that may help reduce the rate of scarring in your lungs), cough suppressants, oxygen therapy if you have a low-level of oxygen in your blood, lung lavage (a specialist procedure to wash out your lungs). […] Silicosis can be prevented by: avoiding prolonged exposure to silica dust, wearing effective protective equipment, such as masks, wetting down tools and materials to suppress dust, using tools that have dust-collecting attachments. […] All workplaces, employers and employees in Australia must follow workplace health and safety procedures. These regulations give guidance on how to prevent silicosis.

• #70 Silicosis | Treatment & Management | Point of Care

  https://www.statpearls.com/point-of-care/147416

  A coordinated effort of primary care practitioners, pulmonologists, nursing staff, occupational health specialists, and transplant surgeons will lead to the best patient outcomes. […] Nursing staff members are a valuable part of the healthcare team, as they often spend the most time in close contact with the patient and frequently form interpersonal relationships with them. Nurses may pick up crucial medical history details that were previously missed. […] Reassurance and gentle encouragement to reinforce essential lifestyle changes can immensely impact patients lives. […] We could eliminate this preventable and devastating disease with the conjoined effort of medical professionals, public health systems, and industry employers.

• #71 Silicosis: Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/22622-silicosis

  If you work in a job around crystalline silica, you can breathe in dust that will cause lung damage. You can help to prevent silicosis if you use protective equipment. […] You cant cure or reverse silicosis, but your providers can treat it. […] You can only manage silicosis. You cant cure silicosis. Some tips for managing silicosis include: Quit smoking or using tobacco products. Use personal protective equipment or change jobs. Use a bronchodilator to improve airflow. Use supplemental oxygen if necessary. […] If you have silicosis, you should: Quit smoking and using tobacco products. Avoid other lung irritants like secondhand smoke and other air pollutants. Get all of the vaccines your provider recommends. Use the correct personal protective equipment, such as N95 masks or respirators, if you continue to work in a place with silica dust. Regular dust masks or face coverings arent enough. Follow proper procedure for working in a place with silica dust, including ventilation and using wetness to keep the dust down.

• #72 Treating and Managing Silicosis | American Lung Association

  https://www.lung.org/lung-health-diseases/lung-disease-lookup/silicosis/treating-and-managing

  There is no cure for silicosis and once the damage is done it cannot be reversed. Treatment is focused on slowing down the progression of the disease and relieving symptoms. Avoiding further exposure to silica and other irritants such as cigarette smoke is crucial. […] To keep the disease from getting worse, all silicosis patients need to eliminate any more exposure to silica. Other lung irritants, such as indoor and outdoor air pollution, allergens and smoke, should also be avoided. […] Your doctor can help manage your symptoms, but you can also take steps to keep yourself healthy by doing the following: Maintain weight and nutrition with a well-balanced diet. Stay as active as you can by exercising regularly but be careful not to overexert yourself. Prevent respiratory infections that can make your lungs worse. Get vaccinated against the flu every year, and pneumococcal pneumonia as recommended by your doctor. Be vigilant about watching for the development of TB or other infections and see your doctor immediately if one develops. Have a plan to manage flare-ups of the disease.

• #73 Silicosis – Pulmonary Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/pulmonary-disorders/environmental-and-occupational-pulmonary-diseases/silicosis

  Silicosis is caused by inhalation of respirable crystalline silica dust and is characterized by nodular pulmonary fibrosis. The cornerstone of treatment is supportive care and, for severe cases, lung transplantation. […] For chronic silicosis, symptomatic treatment (eg, bronchodilators and inhaled corticosteroids) is recommended. […] There are no proven, specific treatments for chronic silicosis. Treatment is primarily supportive. […] Patients with airway obstruction may benefit from bronchodilators and inhaled corticosteroids. Patients should be monitored and treated for hypoxemia. […] Pulmonary rehabilitation may help patients carry out activities of daily living. […] Patients who develop end-stage lung disease may be eligible for lung transplantation. […] Treatment of latent TB infection is recommended in patients with silicosis. […] Infections, including tuberculosis, should be treated promptly.

• #74 Silicosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK594245/

  In individuals exposed to silica, diagnosing silicosis early and counseling patients on avoiding further RCS exposure and smoking cessation is essential to disease management. […] A coordinated effort of primary care practitioners, pulmonologists, nursing staff, occupational health specialists, and transplant surgeons will lead to the best patient outcomes. […] Nursing staff members are a valuable part of the healthcare team, as they often spend the most time in close contact with the patient and frequently form interpersonal relationships with them. […] Reassurance and gentle encouragement to reinforce essential lifestyle changes can immensely impact patients lives. […] Occupational health nurses are specifically beneficial, as they are trained to provide education on risk factors and prevention strategies at worksites.

• #75 Silicosis Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/302027-treatment

  Cell-based therapy, including bone marrow-derived mononuclear cells and mesenchymal cell transplantation, are currently undergoing trials in humans. […] Lung transplantation remains the only treatment option for end-stage silicosis. However, based on available data, patients with silicosis who underwent lung transplantation (4.9%) showed a nonstatistically significant survival advantage (hazard ratio: 0.6) compared to those undergoing the procedure for idiopathic pulmonary fibrosis (IPF). […] Primary prevention of silicosis through exposure control is important, because no effective medical treatment exists for this disease, which continues to progress even after a person is removed from further exposure. […] To achieve this, a sustained effort must be made to increase awareness of silicosis.

• #76 Silicosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK594245/

  Silicosis is a preventable disease with significant morbidity and mortality that has no cure. Education on prevention, screening, timely diagnosis, avoidance of exacerbating factors, and treatment of complications is imperative. […] This activity reviews the etiology, epidemiology, pathogenesis, pathophysiology, clinical evaluation, and management of silicosis and highlights the role of the interprofessional team in caring for patients with this occupational pneumoconiosis. […] There is currently no effective treatment for silicosis. Most interventions are supportive and consist of supplemental oxygen in those with hypoxia, recommended vaccinations, prompt treatment of infection, and pulmonary rehabilitation. […] Although silicosis is currently untreatable, it is undoubtedly preventable. Primary prevention by controlling RCS exposure is critical.

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