Materiały źródłowe

• #1 Esthesioneuroblastoma – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK539694/

  Esthesioneuroblastoma, or olfactory neuroblastoma, is a rare malignant neoplasm of the sinonasal tract originating from the olfactory neuroepithelium with neuroblastic differentiation. This activity reviews the evaluation, diagnosis, and management of esthesioneuroblastoma and the role of team-based interprofessional care for affected patients. […] Describe an optimally functioning interprofessional team approach to coordinate care and enhance outcomes for patients with esthesioneuroblastoma. […] Management of esthesioneuroblastoma is complex and needs an interprofessional approach involving a team that consists of an otolaryngologist, a neurosurgeon, a radiation oncologist, a pathologist, a radiologist, and an oncologist, with support from nursing and pharmacy, where indicated, as treatment moves forward. Specialty care nurses and pharmacists can be integral parts of the team. Pharmacists review medications, detect drug-drug interactions and provide patient education. Specialty trained nurses in otolaryngology and oncology are involved in the initial evaluation, monitor patients, patient education, and supply updated information to the team.

• #2 Esthesioneuroblastoma – Prognosis and Treatmentphone iconphone iconGroup 49

  https://www.barrowneuro.org/condition/esthesioneuroblastoma/

  Esthesioneuroblastoma is a rare head and neck cancer that starts in the very upper part of your nose, in an area that’s crucial for your sense of smell. […] Treatment often involves a multi-faceted approach. Surgery to remove the tumor is common. If it has spread to nearby structures, you might also need radiation therapy or chemotherapy. […] Regular follow-up is crucial to monitor for any signs of the cancer returning and to manage any side effects from treatment. […] Working closely with your healthcare team, who can guide you through the diagnosis, treatment options, and what to expect during recovery, is essential. […] After completing treatment, regular follow-up visits are crucial to monitor for signs of cancer recurrence and manage any side effects from the treatment. […] Supportive care services, including nutritional counseling, pain management, psychological support, and rehabilitation therapies, are essential to help manage these challenges.

• #3 Esthesioneuroblastoma: Multimodal management and review of literature

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4568526/

  Esthesioneuroblastoma (ENB) is a rare malignant neoplasm arising from the olfactory neuroepithelium. ENB constitutes only 3% of all malignant intranasal neoplasm. Because of the rarity, the number of patients of ENB treated in individual departments is small. Most of these patients presents in locally advanced stages and require multimodality treatment in form of surgery, chemotherapy and radiotherapy. Multimodality approach with a risk-adapted strategy is required to achieve good control rates while minimizing treatment related toxicity. […] The various treatment modalities used in the management of ENB are surgery, chemotherapy, radiation therapy (RT) and palliative care. Nowadays, the multimodal approach is recommended for improved survival and quality of life of the patients. […] The mainstay of the treatment is surgery. The advantage of surgery is tumor removal, immediate improvement in compressive symptoms, proper tissue for histopathological and prognostic evaluation.

• #4 Childhood Esthesioneuroblastoma – NCI

  https://www.cancer.gov/types/head-and-neck/patient/child/esthesioneuroblastoma-treatment-pdq

  Childhood esthesioneuroblastoma is a rare type of cancer that forms in the olfactory nerve endings in the upper part of the nasal cavity. […] Esthesioneuroblastoma affects adults and children. Even though it is very rare, esthesioneuroblastoma is the most common nasal cavity cancer in children and teens. […] A pediatric oncologist, a doctor who specializes in treating children with cancer, oversees treatment of esthesioneuroblastoma. The pediatric oncologist works with other health care providers who are experts in treating children with cancer and who specialize in certain areas of medicine. […] There are different types of treatment for children and adolescents with esthesioneuroblastoma. You and your child’s care team will work together to decide treatment. Many factors will be considered, such as your child’s overall health and whether the cancer is newly diagnosed or has come back.

• #5 Esthesioneuroblastoma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/esthesioneuroblastoma/diagnosis-treatment/drc-20446400

  Our caring team of Mayo Clinic experts can help you with your esthesioneuroblastoma-related health concerns […] Esthesioneuroblastoma treatment usually involves surgery to remove the cancer. Other treatments include radiation and chemotherapy. […] Treatment for esthesioneuroblastoma usually involves a team of experts with different specialties. The team might include: Surgeons who operate on the nervous system, known as neurosurgeons. Head and neck surgeons. Doctors who use radiation to treat cancer, known as radiation oncologists. Doctors who use medicine to treat cancer, known as medical oncologists. […] If the person with esthesioneuroblastoma is a child, the team also might include specialists in pediatric surgery and oncology. […] Radiation therapy uses powerful energy beams to kill cancer cells. The energy can come from X-rays, protons or other sources. People with esthesioneuroblastoma often have radiation therapy after surgery to kill any cancer cells that might remain in the head and neck.

• #6 Esthesioneuroblastoma | Tampa General Hospital

  https://www.tgh.org/institutes-and-services/conditions/esthesioneuroblastoma

  Because esthesioneuroblastomas develop in a sensitive area near the brain, this nasal cancer requires highly specialized treatment. […] At TGH, our neurosurgeons and ENT surgeons work closely with other specialists, including radiation oncologists, medical oncologists, radiologists and pathologists, to provide comprehensive skull base surgical care for our patients with esthesioneuroblastomas and other complex neural tumors.

• #7 Esthesioneuroblastoma | UM Health-Sparrow

  https://www.uofmhealthsparrow.org/departments-conditions/conditions/esthesioneuroblastoma

  Esthesioneuroblastoma treatment usually includes surgery. Often, radiation and chemotherapy are part of the treatment as well. […] Esthesioneuroblastoma treatment usually involves surgery to remove the cancer. Other treatments include radiation and chemotherapy. […] Treatment for esthesioneuroblastoma usually involves a team of experts with different specialties. The team might include: Surgeons who operate on the nervous system, known as neurosurgeons. Head and neck surgeons. Doctors who use radiation to treat cancer, known as radiation oncologists. Doctors who use medicine to treat cancer, known as medical oncologists. […] If the person with esthesioneuroblastoma is a child, the team also might include specialists in pediatric surgery and oncology. […] Surgery complications might include spinal fluid leaking into the nose, infection and vision problems.

• #7 Esthesioneuroblastoma | UM Health-Sparrow

  https://www.uofmhealthsparrow.org/departments-conditions/conditions/esthesioneuroblastoma

  Radiation therapy uses powerful energy beams to kill cancer cells. The energy can come from X-rays, protons or other sources. People with esthesioneuroblastoma often have radiation therapy after surgery to kill any cancer cells that might remain in the head and neck. […] If surgery isn’t possible, radiation therapy can be used alone or with chemotherapy. […] Chemotherapy uses strong medicines to kill cancer cells. In people with esthesioneuroblastoma, chemotherapy might be used with radiation therapy after surgery to kill cancer cells that remain. […] No alternative medicine treatments can cure esthesioneuroblastoma. But complementary and alternative medicine therapies may help with the side effects of treatment. Talk with your healthcare team about your options. […] Learn enough about your cancer to make decisions about your care. To know more about your esthesioneuroblastoma, ask your healthcare professional for the details, such as the type and grade. Ask where to find good sources of information about treatments. Knowing more might help you feel better about making treatment decisions. […] Keep your friends and family close. Your friends and family can provide much-needed support during your cancer treatment.

• #8 Childhood Esthesioneuroblastoma (PDQ®): Treatment – Patient Information [NCI] | The Children’s Hospital at Montefiore

  https://www.cham.org/health-library/article?id=ncicdr0000789047

  A pediatric oncologist, a doctor who specializes in treating children with cancer, oversees treatment of esthesioneuroblastoma. The pediatric oncologist works with other health care providers who are experts in treating children with cancer and who specialize in certain areas of medicine. Other specialists may include: pediatrician, pediatric surgeon, radiation oncologist, pathologist, pediatric nurse specialist, social worker, rehabilitation specialist, psychologist, child-life specialist. […] Your child’s treatment plan will include information about the cancer, the goals of treatment, treatment options, and the possible side effects. It will be helpful to talk with your child’s care team before treatment begins about what to expect. […] Surgery to remove the tumor is one of the main treatments for esthesioneuroblastoma. After the doctor removes all the cancer that can be seen at the time of the surgery, your child may be given chemotherapy or radiation therapy to kill any cancer cells that are left. Treatment given after surgery to lower the risk that the cancer will come back is called adjuvant therapy.

• #9 Childhood Esthesioneuroblastoma Treatment (PDQ®) – NCI

  https://www.cancer.gov/types/head-and-neck/hp/child/esthesioneuroblastoma-treatment-pdq

  The use of multimodal therapy optimizes the chances for survival, with more than 70% of children expected to survive 5 or more years after initial diagnosis. […] Treatment options according to Kadish stage include the following: […] The mainstay of treatment is surgery and radiation therapy. However, esthesioneuroblastoma is a chemosensitive neoplasm, and the use of neoadjuvant chemotherapy can facilitate resection. […] Reports have indicated promising results with the increased use of resection and neoadjuvant or adjuvant chemotherapy in patients with advanced-stage disease. […] Chemotherapy regimens that have been used with efficacy include the following: […] Routine neck dissection and nodal exploration are not indicated in the absence of clinical or radiological evidence of disease.

• #10 Childhood Esthesioneuroblastoma Treatment (PDQ®): Treatment – Health Professional Information [NCI] – Health Information Library | PeaceHealth

  https://www.peacehealth.org/medical-topics/id/ncicdr0000790381

  The use of multimodal therapy optimizes the chances for survival, with more than 70% of children expected to survive 5 or more years after initial diagnosis. […] Treatment options according to Kadish stage include the following: Kadish stage A: Surgery alone with clear margins. Adjuvant radiation therapy is indicated in patients with close and positive margins or with residual disease. […] The mainstay of treatment is surgery and radiation therapy. However, esthesioneuroblastoma is a chemosensitive neoplasm, and the use of neoadjuvant chemotherapy can facilitate resection. […] Routine neck dissection and nodal exploration are not indicated in the absence of clinical or radiological evidence of disease. […] Reports have indicated promising results with the increased use of resection and neoadjuvant or adjuvant chemotherapy in patients with advanced-stage disease.

• #11 Esthesioneuroblastoma Treatment & Management: Approach Considerations, Surgical Care, Consultations

  https://emedicine.medscape.com/article/278047-treatment

  Surgery remains the primary treatment for esthesioneuroblastoma (ENB) and offers the best chance for locoregional control as well as survival. Both open and endoscopic craniofacial resection have achieved complete surgical resection with tumor-free margins. In the recent decades, craniofacial resection followed by radiation therapy has been repeatedly referred to as the gold standard for treatment, and thus, other treatment modalities should be measured against it. […] In the first 48 hours following craniofacial resection, regular neurosurgical evaluation is required. ICU monitoring for at least 24 hours also is necessary. Duration of the lumbar drainage is controversial, varying from intraoperative only to as long as 7 days. […] No specific postoperative dietary restrictions are required for patients with esthesioneuroblastoma (ENB). Following major surgery, patients tolerate only light meals during the first postoperative days. Patients with a history of constipation should be given stool softeners for the first postoperative week to prevent undue straining and allow the skull base repair to heal.

• #12 Esthesioneuroblastoma: Multimodal management and review of literature

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4568526/

  Due to locally infiltrative nature of the disease, surgically clear margins are difficult to achieve. Thus there is a role of adjuvant RT to minimize the risk of local recurrence. […] Adjuvant RT is indicated for Kadish stage B and C, whereas Kadish A disease can be managed with surgery alone. […] The role of chemotherapy is not very clear in adjuvant settings in early tumors, but in locally advanced and metastatic tumors it has a definitive role. […] In small local recurrences, stereotactic radiosurgery and stereotactic radiotherapy can be used even for re-radiation. […] Systemic chemotherapy and palliative RT to local site and metastatic sites are advised. Palliative care should be incorporated for improving the quality of life. […] Most of the patients of ENB present in locally advanced stage and the optimal management depends on the cooperation between clinicians, surgeons, radiologists and pathologists from establishing diagnosis to organizing the therapeutic strategy.

• #13

  https://content-dev.irisoncology.com/library/esthesioneuroblastoma

  Esthesioneuroblastoma treatment usually includes surgery. Often, radiation and chemotherapy are part of the treatment as well. […] Esthesioneuroblastoma treatment usually involves surgery to remove the cancer. Other treatments include radiation and chemotherapy. […] Treatment for esthesioneuroblastoma usually involves a team of experts with different specialties. The team might include: Surgeons who operate on the nervous system, known as neurosurgeons. Head and neck surgeons. Doctors who use radiation to treat cancer, known as radiation oncologists. Doctors who use medicine to treat cancer, known as medical oncologists. […] If surgery isn’t possible, radiation therapy can be used alone or with chemotherapy. […] Chemotherapy uses strong medicines to kill cancer cells. In people with esthesioneuroblastoma, chemotherapy might be used with radiation therapy after surgery to kill cancer cells that remain.

• #14 Esthesioneuroblastoma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/esthesioneuroblastoma/diagnosis-treatment/drc-20446400

  Chemotherapy uses strong medicines to kill cancer cells. In people with esthesioneuroblastoma, chemotherapy might be used with radiation therapy after surgery to kill cancer cells that remain. […] An esthesioneuroblastoma diagnosis can feel scary. With time, you’ll likely find good ways to cope with your diagnosis. […] To know more about your esthesioneuroblastoma, ask your healthcare professional for the details, such as the type and grade. […] Your friends and family can provide much-needed support during your cancer treatment.

• #15 Childhood Esthesioneuroblastoma Treatment (PDQ®): Treatment – Health Professional Information [NCI] – Health Information Library | PeaceHealth

  https://www.peacehealth.org/medical-topics/id/ncicdr0000790381

  Chemotherapy regimens that have been used with efficacy include the following: Cisplatin and etoposide with or without ifosfamide. […] The American Academy of Pediatrics has outlined guidelines for pediatric cancer centers and their role in the treatment of children and adolescents with cancer. […] Children and adolescents with cancer should be referred to medical centers that have a multidisciplinary team of cancer specialists with experience treating the cancers that occur during childhood and adolescence. […] Pediatric oncology nurses are part of the multidisciplinary team approach to ensure that children receive treatment, supportive care, and rehabilitation to achieve optimal survival and quality of life.

• #16 Endoscopic Management of Esthesioneuroblastoma | Ento Key

  https://entokey.com/endoscopic-management-of-esthesioneuroblastoma/

  Esthesioneuroblastoma is a rare sinonasal malignancy presenting with nonspecific sinonasal complaints. […] Preoperative assessment and imaging are essential to guide surgical approach. […] Endoscopic endonasal resection is feasible in select cases with the goal of obtaining negative margins. […] Management of ENB is generally surgical, with evidence suggesting that surgery with adjuvant radiation may provide the best prognosis. […] The goal of treatment of ENB is complete surgical resection with negative margins. However, the treatment plan should be individualized for each patient. […] In advanced cases where cure is unlikely, the surgeon must have an honest discussion with the patient and his or her family regarding goals of care and palliative care. […] Preoperative planning begins with comprehensive history and physical by the neurosurgeon and the otolaryngologist-head and neck surgeon.

• #17 Endoscopic Management of Esthesioneuroblastoma | Ento Key

  https://entokey.com/endoscopic-management-of-esthesioneuroblastoma/

  Preoperative imaging is essential to determining not only the extent of disease but also the ability to obtain a negative surgical margin. […] Ultimately, careful preoperative evaluation and surgeon experience should guide the choice of surgical approach that is most likely to yield negative margins in the safest and least invasive manner possible. […] Surgical resection is performed with an endoscopic sinus and neurosurgeon team using a two-surgeon, three- to four-handed technique.

• #18 Esthesioneuroblastoma – Prognosis and Treatmentphone iconphone iconGroup 49

  https://www.barrowneuro.org/condition/esthesioneuroblastoma/

  The treatment plan for esthesioneuroblastoma is highly individualized, taking into account factors like the tumor’s size, location, whether the cancer has spread, and your general health. […] It’s important to have a detailed discussion with your healthcare team about the recommended treatment strategy, including the benefits, risks, and potential side effects, to make informed decisions about your care.

• #19 Childhood Esthesioneuroblastoma – NCI

  https://www.cancer.gov/types/head-and-neck/patient/child/esthesioneuroblastoma-treatment-pdq

  Your child’s treatment plan will include information about the cancer, the goals of treatment, treatment options, and the possible side effects. It will be helpful to talk with your child’s care team before treatment begins about what to expect. […] Surgery to remove the tumor is one of the main treatments for esthesioneuroblastoma. […] After the doctor removes all the cancer that can be seen at the time of the surgery, your child may be given chemotherapy or radiation therapy to kill any cancer cells that are left. Treatment given after surgery to lower the risk that the cancer will come back is called adjuvant therapy. […] Radiation therapy uses high-energy x-rays or other types of radiation to kill cancer cells or keep them from growing. Esthesioneuroblastoma may be treated with external beam radiation therapy.

• #20 Esthesioneuroblastoma Treatment & Management: Approach Considerations, Surgical Care, Consultations

  https://emedicine.medscape.com/article/278047-treatment

  Some surgeons routinely place a lumbar drain to decrease pressure on the dural repair. The authors tend to restrict cerebrospinal fluid decompression to cases with significant dural sacrifice and replacement and/or when the base of skull repair is deemed fragile. As long as the drain remains in place, patients require strict bed rest. Otherwise, patients usually are out of bed on the first postoperative day. […] Craniofacial resection for esthesioneuroblastoma (ENB) has been associated with a complication rate of 10-15%. Higher rates of complications (up to 30%) have been observed in cases of revision or salvage surgery or surgery following radiation or chemoradiation therapy. The most frequent problems are infections, including abscess surrounding the bone flap; meningitis; and, less often, subdural or epidural abscess. […] Recurrence may occur years after the completion of treatment, often more than 10 years; therefore, prolonged follow-up is required. However, the optimal frequency of medical visits and the necessity of radiologic studies have not been precisely determined.

• #21 Olfactory Neuroblastoma Treatment NYC | Mount Sinai – New York

  https://www.mountsinai.org/locations/skull-base-surgery-center/conditions/neuroblastoma-olfactory

  Olfactory neuroblastoma is a rare form of cancer that involves the nasal cavity. […] Whenever possible, complete surgical resection coupled with postoperative radiation therapy is recommended. […] Depending on the size of the tumor and extent of surgery, patients are usually discharged from the hospital after 3-7 days with the first 1-2 nights spent in the Neurocritical Care Unit. […] Care must be used to avoid nose blowing; patients should expect to have nasal packs in place for approximately a week. […] Once discharged, the first postoperative visit is within one week of surgery to help plan the adjuvant therapy with the assistance of the oncologist.

• #22 Esthesioneuroblastoma ENT Treatment in Utah – ENT Center of Utah

  https://entcenterutah.com/adult-care/head-neck-oncology/esthesioneuroblastoma/

  Esthesioneuroblastoma treatments include surgery, radiation and chemotherapy. […] Treatment for Esthesioneuroblastoma usually includes radiation and surgery. Chemotherapy is an additional treatment option that may be used. […] Normally, a neurosurgeon and a head and neck surgeon work with each other as a team to remove Esthesioneuroblastoma safely and effectively. […] High-energy beams, such as X-rays or protons, are use in radiation therapy to eliminate cancer cells. […] People with Esthesioneuroblastoma typically undergo radiation therapy following surgery to eliminate any microscopic cancer cells that might have survived in the head and neck. […] Radiation therapy can also be used by itself or in conjunction with chemotherapy if surgery is not a realistic option because of health concerns or if the cancer is too advanced to be removed by means of an operation.

• #23 Esthesioneuroblastoma ENT Treatment in Utah – ENT Center of Utah

  https://entcenterutah.com/adult-care/head-neck-oncology/esthesioneuroblastoma/

  Because Esthesioneuroblastoma is close to many vital structures in your head, like your brain and your eyes, radiation beams must be aimed specifically to center in on cancer cells and save the healthy tissue that is nearby. […] Chemotherapy uses medications to eliminate cancer cells. In individuals with Esthesioneuroblastoma, chemotherapy is used with radiation therapy following surgery to eliminate any cancer cells that may be left behind, particularly for cancers that are aggressive or widespread.

• #24 Childhood Esthesioneuroblastoma (PDQ®): Treatment – Patient Information [NCI] | The Children’s Hospital at Montefiore

  https://www.cham.org/health-library/article?id=ncicdr0000789047

  Radiation therapy uses high-energy x-rays or other types of radiation to kill cancer cells or keep them from growing. Esthesioneuroblastoma may be treated with external beam radiation therapy. This type of radiation therapy uses a machine outside the body to send radiation toward the area of the body with cancer. Radiation therapy may be given alone or with other treatments, such as chemotherapy. […] Chemotherapy (also called chemo) uses drugs to stop the growth of cancer cells. Chemotherapy either kills the cells or stops them from dividing. Chemotherapy may be given alone or with other types of treatment, such as radiation therapy. […] Treatment of newly diagnosed stage A esthesioneuroblastoma may include: surgery to remove the tumor followed by radiation therapy if visible tumor cells remain after surgery.

• #25 Childhood Esthesioneuroblastoma – NCI

  https://www.cancer.gov/types/head-and-neck/patient/child/esthesioneuroblastoma-treatment-pdq

  Chemotherapy (also called chemo) uses drugs to stop the growth of cancer cells. Chemotherapy either kills the cells or stops them from dividing. Chemotherapy may be given alone or with other types of treatment, such as radiation therapy. […] Treatment of newly diagnosed stage A esthesioneuroblastoma may include: surgery to remove the tumor followed by radiation therapy if visible tumor cells remain after surgery. […] Treatment of newly diagnosed stage B esthesioneuroblastoma may include: surgery to remove the tumor followed by radiation therapy. […] Treatment of newly diagnosed stage C esthesioneuroblastoma may include: chemotherapy followed by surgery to remove the tumor, radiation therapy followed by surgery to remove the tumor, chemotherapy and radiation therapy given at the same time followed by surgery to remove the tumor.

• #26 Esthesioneuroblastoma: Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/esthesioneuroblastoma

  Esthesioneuroblastoma often comes back, so you’ll need annual checkups and tests to be sure the tumor hasn’t returned. […] Healthcare providers treat it with surgery to remove the tumor, followed by radiation therapy. […] Healthcare providers typically do surgery to remove cancerous tumors. […] Other treatments are: Radiation therapy to kill any cancerous cells that remain after surgery. […] Surgery, radiation therapy and chemotherapy have different side effects: Surgery side effects include pain, nasal stuffiness and reaction to anesthesia. […] Esthesioneuroblastoma can come back, so you should plan on seeing your care team at least once a year for the rest of your life. Your team will check on your overall health. They may do imaging tests to look for signs of recurring esthesioneuroblastoma.

• #27 Esthesioneuroblastoma Treatment | Expert Surgeon | Aaron Cohen-Gadol, MD

  https://www.aaroncohen-gadol.com/en/patients/esthesioneuroblastoma/treatment

  Esthesioneuroblastoma, or olfactory neuroblastoma, is a rare form of cancer that starts in the upper part of the nasal cavity. Effective treatment usually requires a combination of approaches, including surgery, radiation therapy, and sometimes chemotherapy. […] Each patient’s treatment plan is personalized to ensure the best possible outcome, focusing on complete tumor removal while managing side effects and maintaining quality of life. […] Supportive care is vital in helping patients manage side effects and maintain their quality of life during and after treatment. […] The risk of recurrence is a major concern with esthesioneuroblastoma. Regular follow-up appointments are crucial for monitoring any signs of the tumor returning. […] Follow-up care usually includes periodic imaging and physical exams. Early detection of recurrence allows for more immediate intervention, which can significantly improve outcomes. […] Treating esthesioneuroblastoma involves a combination of surgery, radiation, and sometimes chemotherapy.

• #28

  https://content-dev.irisoncology.com/library/esthesioneuroblastoma

  No alternative medicine treatments can cure esthesioneuroblastoma. But complementary and alternative medicine therapies may help with the side effects of treatment. […] An esthesioneuroblastoma diagnosis can feel scary. With time, you’ll likely find good ways to cope with your diagnosis. Until you find what works for you, consider trying to: Learn enough about your cancer to make decisions about your care. […] Your friends and family can provide much-needed support during your cancer treatment.

• #29 Esthesioneuroblastoma Overview | Expert Surgeon | Aaron Cohen-Gadol, MD

  https://www.aaroncohen-gadol.com/en/patients/esthesioneuroblastoma/overview

  Surgery is often the primary treatment, with the goal of removing as much of the tumor as possible. Given the tumor’s location, precise surgical techniques are necessary. […] Radiation therapy is often recommended after surgery to target any remaining cancer cells and reduce the risk of recurrence. It may also be used as the main treatment for patients when surgery isn’t an option. […] Managing the side effects of treatment and ensuring quality of life is essential in one’s recovery journey. […] Counseling and support groups are available to help patients and families cope with the challenges of diagnosis and treatment, offering valuable resources throughout the cancer journey. […] With a multidisciplinary approach involving surgery, radiation, and supportive care, patients have confidence in managing the disease and maintaining their quality of life.

• #30 Olfactory Neuroblastoma | Duke Health

  https://www.dukehealth.org/treatments/cancer/olfactory-neuroblastoma

  Olfactory neuroblastoma requires advanced care. Because olfactory neuroblastoma tumors grow near important structures like the brain, nose, eyes, and facial nerves, your care team should include multiple specialists. At Duke, a head and neck surgeon and/or sinus specialist serves as your primary doctor. Neurosurgeons, oncologists, neuro-ophthalmologists, plastic surgeons, and others may also be involved in your care as needed. […] Long-term follow-up is important as olfactory neuroblastomas can recur many years after successful treatment. It’s important to seek care at a center like Duke, where our specialists offer quality, long-term monitoring for this and other types of rare cancers. […] Surgery to remove the tumor combined with radiation therapy is the standard treatment for olfactory neuroblastoma. Your care team may also recommend chemotherapy before or after surgery. […] Patient navigators coordinate your care. Our patient navigator guides you through every step of your treatment. They help schedule appointments, coordinate visits, communicate your test results, and prepare you for surgery. And they are available to answer all your questions along the way.

• #31 Esthesioneuroblastoma (Olfactory Neuroblastoma) – Symptoms Causes & Treatments

  https://www.uchealth.com/en/conditions/esthesioneuroblastoma

  Chemotherapy may be used in combination with surgery and radiation, particularly in advanced cases or when there’s a high risk of recurrence. […] The treatment of esthesioneuroblastoma requires careful planning and coordination among various specialties to achieve the best possible outcome. Regular follow-up is crucial to watch for recurrence or complications arising from treatment. […] Living with esthesioneuroblastoma presents unique challenges. For patients and their families, adapting to life during and after treatment is a journey that requires support and resilience. […] Support networks can be important. Healthcare professionals, including oncologists, nurses, and counselors, provide essential medical and psychological support. […] Pediatric esthesioneuroblastoma, although rare, requires special consideration due to the unique needs of children and adolescents. Treatment protocols for children often differ from adults, emphasizing the need for specialized pediatric oncology care.

• #32 Childhood Esthesioneuroblastoma (PDQ®): Treatment – Patient Information [NCI] | The Children’s Hospital at Montefiore

  https://www.cham.org/health-library/article?id=ncicdr0000789047

  Treatment of newly diagnosed stage B esthesioneuroblastoma may include: surgery to remove the tumor followed by radiation therapy. […] Treatment of newly diagnosed stage C esthesioneuroblastoma may include: chemotherapy followed by surgery to remove the tumor, radiation therapy followed by surgery to remove the tumor, chemotherapy and radiation therapy given at the same time followed by surgery to remove the tumor. […] Treatment of newly diagnosed stage D esthesioneuroblastoma may include: chemotherapy given before or after surgery to remove the tumor, radiation therapy to the tumor and other places in the body where the cancer has spread. […] If the cancer comes back after treatment, your child’s doctor will talk with you about what to expect and possible next steps. There might be treatment options that may shrink the cancer or control its growth. If there are no treatments, your child can receive care to control symptoms from cancer so they can be as comfortable as possible.

• #33 Childhood Esthesioneuroblastoma – NCI

  https://www.cancer.gov/types/head-and-neck/patient/child/esthesioneuroblastoma-treatment-pdq

  Treatment of newly diagnosed stage D esthesioneuroblastoma may include: chemotherapy given before or after surgery to remove the tumor, radiation therapy to the tumor and other places in the body where the cancer has spread. […] If the cancer comes back after treatment, your child’s doctor will talk with you about what to expect and possible next steps. There might be treatment options that may shrink the cancer or control its growth. If there are no treatments, your child can receive care to control symptoms from cancer so they can be as comfortable as possible.

• #34 Esthesioneuroblastoma | University Hospitals

  https://www.uhhospitals.org/services/cancer-services/neuro-oncology/diagnosis-and-treatments/esthesioneuroblastoma

  Through our commitment to patient-centered care, we compassionately guide our patients with esthesioneuroblastoma through the treatment process, ensuring that they are fully educated every step of the way. Our personalized medical services are designed to satisfy the whole person, meeting each patients unique physical and emotional needs. […] At UH Seidman Cancer Center, our patients benefit from a team approach to treating esthesioneuroblastoma. Our patients see multiple specialists who work together to create the most comprehensive, individualized cancer care plan possible. […] Our multidisciplinary cancer team meets weekly for a disease-specific tumor board review. Tumor board review involves a meeting where every single patients case is read and discussed among a team of national experts to guide the cancer care treatment plan. This review process ensures that all realistic treatment options for brain stem cancer are considered.

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