Denga
Objawy

Denga to wirusowa choroba przenoszona przez komary, charakteryzująca się trzema fazami: gorączkową, krytyczną i zdrowienia. Faza gorączkowa trwa 2-7 dni i obejmuje wysoką gorączkę do 40-41°C, ból głowy, mięśni i stawów, nudności, wysypkę oraz łagodne objawy krwotoczne. Faza krytyczna, trwająca 24-48 godzin, pojawia się po ustąpieniu gorączki i wiąże się z ryzykiem ciężkich powikłań, takich jak przesięki osocza, krwawienia, hipoproteinemia, hemokoncentracja oraz objawy wstrząsu (ciśnienie tętnicze <20 mmHg). Faza zdrowienia trwa 2-3 dni i charakteryzuje się poprawą kliniczną, stabilizacją parametrów życiowych oraz powrotem liczby płytek krwi do normy. U około 5% pacjentów rozwija się ciężka denga z ryzykiem niewydolności wielonarządowej i wysoką śmiertelnością bez odpowiedniego leczenia.

Denga (dengue) – objawy i przebieg

Denga to choroba wirusowa przenoszona przez komary, wywoływana przez wirusa dengi (DENV). Charakteryzuje się szerokim spektrum objawów – od bezobjawowego przebiegu do ciężkiej choroby zagrażającej życiu. Objawy pojawiają się zazwyczaj po okresie inkubacji trwającym od 3 do 14 dni (najczęściej 4-7 dni) od ukąszenia zainfekowanego komara 12.

Fazy przebiegu dengi

Denga zwykle przebiega w trzech charakterystycznych fazach: gorączkowej, krytycznej i zdrowienia 34.

Faza gorączkowa

Faza gorączkowa to początkowy etap choroby, który charakteryzuje się nagłym wystąpieniem wysokiej gorączki, często osiągającej 40°C (104°F). Ta faza zazwyczaj trwa od 2 do 7 dni i obejmuje następujące objawy 56:

  • Nagła wysoka gorączka (do 40-41°C) 7
  • Silny ból głowy, szczególnie za oczami (ból zaoczodołowy) 8
  • Intensywny ból mięśni i stawów (stąd określenie „gorączka łamańca kości”) 9
  • Zaczerwienienie twarzy i skóry 10
  • Nudności i wymioty 11
  • Powiększenie węzłów chłonnych 12
  • Wysypka skórna, która może pojawić się po 2-5 dniach od początku gorączki 13
  • Łagodne objawy krwotoczne, takie jak łatwe siniaczenie i krwawienie 14
Faza krytyczna

Faza krytyczna rozpoczyna się zwykle w momencie ustąpienia gorączki (deferwescencji), około 3-7 dnia choroby, kiedy temperatura spada do około 37,5-38°C lub niżej. Ta faza trwa zazwyczaj 24-48 godzin i jest najbardziej niebezpieczna 1516.

Podczas fazy krytycznej mogą pojawić się następujące objawy 1718:

  • Zwiększona przepuszczalność naczyń krwionośnych prowadząca do przesięków osocza 19
  • Silny ból brzucha 20
  • Uporczywe wymioty (co najmniej 3 razy w ciągu 24 godzin) 21
  • Krwawienie z dziąseł lub nosa 22
  • Wymioty z krwią lub krew w stolcu 23
  • Przyspieszone oddychanie 24
  • Akumulacja płynów w jamie opłucnej i jamie brzusznej 25
  • Hipoproteinemia 26
  • Hemokoncentracja (wzrost hematokrytu) 27
  • Zmęczenie, niepokój lub drażliwość 28
  • Chłodna, blada skóra 29

Faza krytyczna jest momentem, w którym może rozwinąć się ciężka postać dengi, wymagająca natychmiastowej interwencji medycznej 30.

Faza zdrowienia

Faza zdrowienia następuje po fazie krytycznej i zazwyczaj trwa 2-3 dni. W tym okresie następuje stopniowe wchłanianie przesiąkniętych płynów i poprawa stanu pacjenta 3132.

Charakterystyczne objawy fazy zdrowienia to 3334:

  • Ogólna poprawa stanu pacjenta 35
  • Powrót apetytu 36
  • Zwiększona diureza (częstsze oddawanie moczu) 37
  • Stabilizacja parametrów życiowych 38
  • Świąd skóry i charakterystyczna wysypka 39
  • Stopniowy powrót poziomu płytek krwi do normy 40
  • Zmniejszenie powiększonej wątroby 41

Warto zaznaczyć, że pomimo poprawy, zmęczenie i osłabienie mogą utrzymywać się przez kilka tygodni po ustąpieniu gorączki 42.

Ciężka postać dengi (denga krwotoczna)

U około 1 na 20 pacjentów (5%) choroba może rozwinąć się w ciężką formę, znaną jako ciężka denga lub gorączka krwotoczna dengi 4344. Jest to stan zagrażający życiu, wymagający natychmiastowej pomocy medycznej.

Ciężka denga charakteryzuje się 4546:

  • Znacznym przesiękiem osocza prowadzącym do wstrząsu lub gromadzenia się płynu z niewydolnością oddechową 47
  • Ciężkim krwawieniem (z nosa, dziąseł, przewodu pokarmowego) 48
  • Ciężkim uszkodzeniem narządów, takim jak 49:
    • Zapalenie wątroby (podwyższone transaminazy >1000 IU/L) 50
    • Zaburzenia świadomości 51
    • Niewydolność mięśnia sercowego 52
    • Niewydolność płuc 53
  • Zespołem wstrząsu w przebiegu dengi (DSS), charakteryzującym się 54:
    • Hipotensją (niskie ciśnienie krwi) 55
    • Zwężoną amplitudą ciśnienia (<20 mmHg) 56
    • Upośledzoną perfuzją narządów 57

Objawy ostrzegawcze ciężkiej dengi zazwyczaj pojawiają się w ciągu 24-48 godzin po ustąpieniu gorączki i wymagają natychmiastowej interwencji medycznej 5859.

Czynniki ryzyka ciężkiego przebiegu dengi

Istnieje kilka czynników zwiększających ryzyko rozwoju ciężkiej postaci dengi 6061:

  • Wcześniejsza infekcja innym serotypem wirusa dengi – osoby, które przeszły wcześniej zakażenie jednym serotypem wirusa dengi, są bardziej narażone na rozwój ciężkiej dengi przy ponownym zakażeniu innym serotypem 6263
  • Wiek – dzieci poniżej 15 roku życia oraz osoby starsze są bardziej narażone na ciężki przebieg 6465
  • Ciąża – kobiety w ciąży są bardziej narażone na ciężki przebieg 66
  • Choroby współistniejące, takie jak cukrzyca, nadciśnienie tętnicze, otyłość czy choroby autoimmunologiczne 67

Zespół po przebytej dendze (Post-Dengue Syndrome, PDS)

U części pacjentów po przebytej dendze mogą występować długotrwałe objawy, które utrzymują się przez tygodnie lub miesiące po ostrym zakażeniu. Stan ten nazywany jest zespołem po przebytej dendze (PDS) 6869.

Objawami zespołu po przebytej dendze mogą być 7071:

  • Przewlekłe zmęczenie i osłabienie 72
  • Bóle mięśni i stawów (mialgię i artralgię) 73
  • Utrata włosów 74
  • Problemy ze wzrokiem 75
  • Zaburzenia neurologiczne (bóle głowy, zaburzenia poznawcze) 76
  • Zmniejszony apetyt 77
  • Zaburzenia nastroju i depresja 78

Częstość występowania zespołu po przebytej dendze różni się w zależności od badania – od około 8-9% do nawet 47% osób z przebytą dengą może doświadczać co najmniej jednego objawu utrzymującego się po ostrym zakażeniu 79.

Różnice w objawach w zależności od wieku i stanu zdrowia

Objawy dengi mogą różnić się w zależności od wieku pacjenta i jego ogólnego stanu zdrowia 8081.

Denga u dzieci

U dzieci denga może prezentować się inaczej niż u dorosłych 82:

  • Młodsze dzieci i niemowlęta częściej doświadczają łagodniejszych objawów 83
  • Mogą wykazywać większą drażliwość niż zwykle 84
  • Zmiana apetytu i wzorców snu 85
  • Wyższe ryzyko wystąpienia drgawek gorączkowych u dzieci poniżej 6 roku życia 86
  • Dzieci poniżej 15 roku życia częściej rozwijają dengę krwotoczną 87

Niemowlęta i małe dzieci są szczególnie narażone na ciężki przebieg dengi i powikłania ze względu na słabszy układ odpornościowy 88.

Denga u osób starszych

U osób starszych objawy dengi mogą być mniej charakterystyczne 89:

  • Mogą doświadczać mniejszych bólów i bólów mięśniowo-stawowych 90
  • Częściej prezentują się z objawami zmęczenia i utratą apetytu 91
  • Wyższe ryzyko ciężkiego przebiegu i powikłań 92
  • Stan zdrowia może pogorszyć się szybciej 93

Ze względu na mniej charakterystyczne objawy, diagnoza dengi u osób starszych może być trudniejsza i opóźniona, co zwiększa ryzyko powikłań 94.

Diagnostyka dengi

Diagnoza dengi opiera się na objawach klinicznych oraz badaniach laboratoryjnych 95.

Badania laboratoryjne w diagnostyce dengi

Do potwierdzenia zakażenia wirusem dengi stosuje się następujące badania 9697:

  • Wykrywanie antygenu NS1 wirusa dengi – zazwyczaj dodatnie przez pierwsze 7 dni choroby 98
  • Badania serologiczne wykrywające przeciwciała IgM i IgG przeciwko wirusowi dengi 99
  • RT-PCR (reakcja łańcuchowa polimerazy z odwrotną transkryptazą) wykrywający RNA wirusa – zazwyczaj dodatnie przez pierwsze 5 dni choroby 100

Dodatkowo, w monitorowaniu przebiegu choroby wykonuje się regularne badania morfologii krwi, ze szczególnym uwzględnieniem liczby płytek krwi i hematokrytu 101.

Monitorowanie pacjenta

U pacjentów z dengą zaleca się regularne monitorowanie następujących parametrów 102:

  • Codzienne pomiary liczby płytek krwi i hematokrytu, gdy liczba płytek spadnie poniżej 100,000/mm³ 103
  • Monitorowanie funkcji narządów wewnętrznych, szczególnie wątroby (transaminazy) 104
  • Kontrola parametrów życiowych, zwłaszcza ciśnienia tętniczego i tętna 105
  • Obserwacja pod kątem objawów ostrzegawczych ciężkiej dengi 106

Leczenie dengi

Nie ma specyficznego leczenia przeciwwirusowego w przypadku dengi. Terapia jest głównie objawowa i wspierająca 107108.

Leczenie łagodnej postaci dengi

W przypadku łagodnej dengi bez objawów ostrzegawczych, leczenie obejmuje 109110:

  • Odpoczynek w łóżku 111
  • Obfite nawodnienie doustne 112
  • Paracetamol do kontroli gorączki i bólu 113
  • Unikanie niesteroidowych leków przeciwzapalnych (NLPZ), takich jak aspiryna czy ibuprofen, które mogą zwiększać ryzyko krwawienia 114
  • Całkowity odpoczynek w łóżku dla pacjentów z liczbą płytek krwi poniżej 50,000/mm³ 115

Leczenie ciężkiej postaci dengi

Ciężka denga wymaga hospitalizacji i intensywnego leczenia 116:

  • Dożylne uzupełnianie płynów i elektrolitów 117
  • Monitorowanie ciśnienia tętniczego 118
  • Transfuzje krwi w przypadku znacznej utraty krwi 119
  • Tlenoterapia w przypadku trudności z oddychaniem 120
  • Monitorowanie funkcji narządów wewnętrznych 121

Wczesne rozpoznanie i odpowiednie leczenie ciężkiej dengi może zmniejszyć śmiertelność do poniżej 1% 122.

Rokowanie i powrót do zdrowia

Rokowanie w przypadku dengi zależy od ciężkości choroby i szybkości podjęcia leczenia 123124.

Rokowanie w łagodnej postaci dengi

W przypadku łagodnej dengi 125126:

  • Większość pacjentów wraca do zdrowia w ciągu 1-2 tygodni 127
  • Śmiertelność jest niska, poniżej 1% 128
  • Zmęczenie i osłabienie mogą utrzymywać się przez kilka tygodni po ustąpieniu gorączki 129

Rokowanie w ciężkiej postaci dengi

W przypadku ciężkiej dengi 130131:

  • Bez odpowiedniego leczenia śmiertelność może sięgać 20-50% 132
  • Przy szybkiej i odpowiedniej interwencji medycznej śmiertelność spada do 2-5% 133
  • Pacjenci z wstrząsem lub niewydolnością wielonarządową mają gorsze rokowanie 134

Czas powrotu do zdrowia

Czas powrotu do zdrowia po dendze zależy od ciężkości choroby 135:

  • Łagodna denga: pełne wyzdrowienie zazwyczaj w ciągu 1-2 tygodni 136
  • Ciężka denga: dłuższy czas rekonwalescencji, często kilka tygodni 137
  • PDS (zespół po przebytej dendze): objawy mogą utrzymywać się tygodniami, miesiącami, a w rzadkich przypadkach nawet dłużej 138

Podczas rekonwalescencji zaleca się odpowiednią ilość odpoczynku, nawodnienie i kontrolę lekarską 139.

Kiedy należy pilnie szukać pomocy medycznej

Istnieją sytuacje, w których pacjent z dengą powinien natychmiast zgłosić się po pomoc medyczną 140141.

Objawy ostrzegawcze wymagające natychmiastowej pomocy

Należy natychmiast szukać pomocy medycznej, jeśli po przebytej gorączce dengi pojawią się następujące objawy 142143:

  • Silny ból brzucha lub tkliwość brzucha 144
  • Uporczywe wymioty (co najmniej 3 razy w ciągu 24 godzin) 145
  • Krwawienie z nosa lub dziąseł 146
  • Krew w wymiocinach lub stolcu 147
  • Przyspieszone lub utrudnione oddychanie 148
  • Bladość, zimna lub wilgotna skóra 149
  • Skrajne zmęczenie, niepokój lub drażliwość 150
  • Trudności w utrzymaniu ciśnienia krwi 151
  • Objawy odwodnienia (zmniejszone oddawanie moczu, suche usta, brak łez) 152

Te objawy mogą wskazywać na rozwijającą się ciężką dengę i stanowią stan zagrożenia życia 153.

Grupy ryzyka wymagające szczególnej uwagi

Niektóre grupy pacjentów powinny być szczególnie uważnie monitorowane i rozważana powinna być hospitalizacja nawet przy łagodnych objawach 154:

  • Dzieci, szczególnie poniżej 15 roku życia 155
  • Osoby starsze 156
  • Kobiety w ciąży 157
  • Osoby z chorobami współistniejącymi, takimi jak cukrzyca, nadciśnienie czy choroby autoimmunologiczne 158
  • Osoby, które przebyły wcześniej zakażenie dengą 159
  • Osoby mieszkające samotnie 160

Wczesna interwencja medyczna w tych grupach ryzyka może zapobiec rozwojowi ciężkiej dengi i potencjalnie śmiertelnym powikłaniom 161.

Kolejne rozdziały

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Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.

  1. 14.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    Dengue is a mosquito-transmitted virus, and dengue fever is the leading cause of arthropod-borne viral disease worldwide, posing a significant global health concern. This disease is also known by various monikers, such as breakbone or 7-day fever, and is characterized by intense muscle spasms, joint pain, and high fever, reflecting both the severity and the duration of symptoms. […] Although most dengue fever cases are asymptomatic, severe illness and mortality can occur. […] The typical incubation period for the disease is 4 to 7 days, with symptoms lasting from 3 to 10 days. Symptoms appearing more than 2 weeks after exposure are unlikely to be attributed to dengue fever. […] The presentation of dengue fever, whether asymptomatic, typical, or severe, is influenced by a complex interplay of host and viral factors. Severe dengue fever, characterized by heightened microvascular permeability and shock syndrome, is often associated with infection by a second dengue virus serotype and the patient’s immune response. However, severe cases of dengue fever can also arise from infection by a single serotype.
  • #2 Dengue Fever (for Parents) | Nemours KidsHealth
    https://kidshealth.org/en/parents/dengue.html
    Dengue fever can cause fever, headaches, rashes, and pain throughout the body. Although it can be very painful, it’s usually not fatal. Most people who get it start feeling better after several days and recover fully in a couple of weeks. […] Dengue fever used to be called „breakbone fever” because of the severe bone and muscle pain it sometimes causes. While the fever does not break any bones, it can sometimes feel like it does. […] A person with dengue fever may notice: a high fever, pain behind the eyes, pain in the joints, muscles, and/or bones, a severe headache, a rash over most of the body, easy bruising. […] Some people can get a more serious form of the infection called dengue hemorrhagic fever. They’ll have the regular symptoms of dengue fever for a few days. After the fever goes down, they also might have these problems: nausea and vomiting, severe belly pain, trouble breathing, bleeding from the nose or gums, vomiting blood, or blood in their stool (poop).
  • #3 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The 3 phases of dengue fever include febrile, critical, and recovery stages. […] During the febrile phase, individuals typically experience a sudden onset of high-grade fever, reaching approximately 40 C, which usually lasts for 2 to 7 days. […] During the critical phase, defervescence marks a period when the temperature typically decreases to approximately 37.5 to 38 C or lower, occurring between days 3 and 7. This phase is associated with heightened capillary permeability and typically lasts for 1 to 2 days. […] The recovery phase involves the gradual reabsorption of extravascular fluid over 2 to 3 days. […] Expanded dengue virus syndrome refers to unusual or atypical manifestations seen in patients with involvement of various organs such as neurological, hepatic, and renal. […] Symptoms include rapidly rising hematocrit, intense abdominal pain, persistent vomiting, and narrowed or absent blood pressure.
  • #4 Understanding Dengue Fever | Saint Luke’s Health System
    https://www.saintlukeskc.org/health-library/understanding-dengue-fever
    Mild dengue infection may have few symptoms. Moderate to severe dengue has 3 phases: febrile, critical, and recovery. […] Symptoms of the febrile phase last 3 to 7 days and include: Sudden high fever, Skin redness or red patches on the skin, Severe headache, Pain behind the eyes, Severe joint and muscle pain, Upset stomach (nausea), Vomiting, Easy bruising and bleeding. […] The critical phase often lasts 2 to 3 days. During this time, body temperature may return to normal. Symptoms of the critical phase include: Vomiting that wont stop, Severe pain in the belly (abdomen), Fluid in the chest and belly, Fast breathing, Low blood pressure, Bleeding. […] A person with severe dengue may have trouble breathing, severe bleeding, damage to organs, or dengue shock syndrome. This can be fatal, and is a medical emergency. […] During the recovery phase, there is overall improvement. There may also be a rash and itchy skin. There may be heart and lung problems.
  • #5 Dengue: Practice Essentials, Background, Pathophysiology
    https://emedicine.medscape.com/article/215840-overview
    Dengue fever typically presents with a sudden onset of high fever, headache, muscle and joint pain, and generalized lymphadenopathy. A rash may develop alongside recurrent fever following an afebrile period, and respiratory symptoms such as cough, sore throat, and rhinorrhea also can occur. […] In more severe cases, dengue can lead to dengue hemorrhagic fever, characterized by a bleeding tendency and shock, which can be fatal. […] Dengue fever typically is a self-limited disease with a mortality rate of less than 1% when detected early and with access to proper medical care. When treated, severe dengue has a mortality rate of 2-5%, but, when left untreated, the mortality rate is as high as 20%. […] On average, dengue becomes symptomatic after a 4- to 10-day incubation period (range, 3-14 days). Dengue symptoms usually last 2-7 days.
  • #6 Dengue: Symptoms, Prevention and Treatments – PAHO/WHO
    https://www.paho.org/en/topics/dengue
    Dengue is transmitted by the bite of an infected mosquito. It is an illness that affects infants, young children, and adults, with symptoms ranging from mild fever to incapacitating high fever, with severe headache, pain behind the eyes, muscle and joint pain, and rash. The illness can evolve to severe dengue, characterized by shock, respiratory distress, severe bleeding, and/or serious organ impairment. […] The infection may be asymptomatic, or it may present with symptoms ranging from a moderate fever to a disabling high fever, with severe headache, pain behind the eyes, muscle and joint pain, and rashes. The disease can evolve into severe dengue, characterized by shock, shortness of breath, severe bleeding and / or complications in the organs. […] Patients develop a sudden, high fever. This acute febrile phase lasts from 2 to 7 days and is usually accompanied by facial flushing, erythema, generalized body pain, myalgia, arthralgia, headache, and retro-ocular pain. Minor hemorrhagic manifestations such as petechiae and skin ecchymoses may occur. Patients who improve after the fever subsides are considered dengue cases without warning signs.
  • #7 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Dengue fever is an illness spread by the bite of mosquitos infected with one of the dengue viruses. Symptoms are usually flu-like but can worsen to severe dengue (dengue hemorrhagic fever), a life-threatening condition. Getting infected a second time increases your risk of serious symptoms. […] Symptoms of dengue are rash, eye pain, nausea or vomiting and muscle pain. If you live in or are visiting an area where dengue is common, seek medical attention immediately if you have warning signs of severe dengue. This includes abdominal pain, blood in your vomit or poop, bleeding gums or nose, frequent vomiting or extreme tiredness or restlessness. […] Most dengue infections dont cause symptoms. If you do have symptoms, high fever (104F/40C) is typical, along with: Rash. Intense pain behind your eyes. Nausea or vomiting. Muscle, bone and joint pain.
  • #8
    https://www.who.int/news-room/questions-and-answers/item/dengue-and-severe-dengue
    Dengue causes flu-like symptoms and lasts for 2-7 days. Dengue fever usually occurs after an incubation period of 4-10 days after the bite of the infected mosquito. […] High Fever (40 C/104 F) is usually accompanied by at least two of the following symptoms: headaches, pain behind eyes, nausea, vomiting, swollen glands, joint, bone or muscle pains, rash. […] Individuals infected for the second time are at greater risk of severe dengue. When developing into severe dengue, the critical phase takes place around 3-7 days after the first sign of illness. […] On the other hand, special attention needs to be given to these warning signs as it could lead to severe dengue: severe abdominal pain, persistent vomiting, bleeding gums, rapid breathing, fatigue/restlessness, blood in vomit or stool, being very thirsty, pale and cold skin. […] Severe dengue can cause: plasma leaking that may lead to shock and/or fluid accumulation with/without respiratory distress; severe bleeding; and severe organ impairment. […] For people with severe dengue, hospitalization is often needed.
  • #9 Symptoms, transmission, and current treatments for dengue | DNDi
    https://dndi.org/diseases/dengue/facts/
    Dengue symptoms range from none to serious flu-like symptoms. A small proportion of people develop severe dengue, which can be fatal. […] Dengue can have no symptoms or cause only mild illness, but it can also cause flu-like symptoms such as: high fever (40C/104F), severe headache, pain behind the eyes, nausea, vomiting, swollen glands, rash, muscle, joint, or bone pains so severe that dengue is sometimes referred to as breakbone fever. […] Severe dengue happens when blood vessels become damaged and leaky, and the number of platelets (cells which form clots) drops. As a result, severe dengue can cause shock, internal bleeding, bleeding gums or nose, organ failure, and death. The symptoms of severe dengue include: severe abdominal pain, persistent vomiting, rapid breathing, bleeding gums or nose, fatigue, restlessness, liver enlargement, blood in vomit or stool, potentially fatal. […] The lack of treatment options increases the risk of people developing severe dengue, which is potentially fatal. […] Dengue-specific treatments are needed to treat the disease at different stages and to reduce the risk of an infection progressing to severe disease.
  • #10 Dengue Clinical Presentation: History, Physical Examination
    https://emedicine.medscape.com/article/215840-clinical
    Patients with dengue will have a history of living in, or recent travel to, a region where the disease is endemic. The incubation period is 3-15 days (average, 4-7 days); symptoms that begin more than 2 weeks after a person departs from an endemic area probably are not due to dengue. […] Many patients experience a prodrome of chills, erythematous mottling of the skin, and facial flushing (a sensitive and specific indicator of dengue fever). The prodrome may last for 2-3 days. Children younger than 15 years usually have a nonspecific febrile syndrome, which may be accompanied by a maculopapular rash. Classic dengue fever begins with sudden onset of fever, chills, and severe (termed breakbone) aching of the head, back, and extremities, as well as other symptoms. The fever lasts 48-96 hours and may reach 41C. Fever that lasts longer than 10 days probably is not due to dengue.
  • #11 Understanding Dengue Fever | Saint Luke’s Health System
    https://www.saintlukeskc.org/health-library/understanding-dengue-fever
    Mild dengue infection may have few symptoms. Moderate to severe dengue has 3 phases: febrile, critical, and recovery. […] Symptoms of the febrile phase last 3 to 7 days and include: Sudden high fever, Skin redness or red patches on the skin, Severe headache, Pain behind the eyes, Severe joint and muscle pain, Upset stomach (nausea), Vomiting, Easy bruising and bleeding. […] The critical phase often lasts 2 to 3 days. During this time, body temperature may return to normal. Symptoms of the critical phase include: Vomiting that wont stop, Severe pain in the belly (abdomen), Fluid in the chest and belly, Fast breathing, Low blood pressure, Bleeding. […] A person with severe dengue may have trouble breathing, severe bleeding, damage to organs, or dengue shock syndrome. This can be fatal, and is a medical emergency. […] During the recovery phase, there is overall improvement. There may also be a rash and itchy skin. There may be heart and lung problems.
  • #12 Dengue – Infectious Diseases – MSD Manual Professional Edition
    https://www.msdmanuals.com/professional/infectious-diseases/arboviruses-arenaviridae-and-filoviridae/dengue
    Dengue fever usually results in abrupt onset of high fever, headache, myalgias, arthralgias, and generalized lymphadenopathy, followed by a rash that appears with a recurrent fever after an afebrile period. […] After an incubation period of 3 to 15 days, fever, chills, headache, retro-orbital pain with eye movement, lumbar backache, and severe prostration begin abruptly. Extreme aching in the legs and joints occurs during the first hours, accounting for the traditional name of breakbone fever. The temperature rises rapidly to up to 40 C, with relative bradycardia. Bulbar and palpebral conjunctival injection and a transient flushing or pale pink macular rash (particularly of the face) may occur. Cervical, epitrochlear, and inguinal lymph nodes are often enlarged. […] Fever and other symptoms persist 48 to 96 hours, followed by rapid defervescence with profuse sweating. Patients then feel well for about 24 hours, after which fever may occur again (saddleback pattern), typically with a lower peak temperature than the first. Simultaneously, a blanching maculopapular rash spreads from the trunk to the extremities and face.
  • #13 Dengue fever Information | Mount Sinai – New York
    https://www.mountsinai.org/health-library/diseases-conditions/dengue-fever
    Dengue fever begins with a sudden high fever, often as high as 105°F (40.6°C), 4 to 7 days after the infection. […] A flat, red rash may appear over most of the body 2 to 5 days after the fever starts. A second rash, which looks
  • #14 Understanding Dengue Fever | Saint Luke’s Health System
    https://www.saintlukeskc.org/health-library/understanding-dengue-fever
    Mild dengue infection may have few symptoms. Moderate to severe dengue has 3 phases: febrile, critical, and recovery. […] Symptoms of the febrile phase last 3 to 7 days and include: Sudden high fever, Skin redness or red patches on the skin, Severe headache, Pain behind the eyes, Severe joint and muscle pain, Upset stomach (nausea), Vomiting, Easy bruising and bleeding. […] The critical phase often lasts 2 to 3 days. During this time, body temperature may return to normal. Symptoms of the critical phase include: Vomiting that wont stop, Severe pain in the belly (abdomen), Fluid in the chest and belly, Fast breathing, Low blood pressure, Bleeding. […] A person with severe dengue may have trouble breathing, severe bleeding, damage to organs, or dengue shock syndrome. This can be fatal, and is a medical emergency. […] During the recovery phase, there is overall improvement. There may also be a rash and itchy skin. There may be heart and lung problems.
  • #15 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Dengue begins abruptly after a typical incubation period of 57 days, and the course follows 3 phases: febrile, critical, and recovery. […] Early clinical findings are nonspecific. Dengue requires a high index of suspicion because recognizing early signs of shock and promptly initiating intensive supportive therapy with intravenous fluids can reduce risk of death among patients with severe dengue to 0.5%. […] Warning signs of progression to severe dengue usually occur in the late febrile phase around the time of defervescence, and include persistent vomiting, severe abdominal pain, fluid accumulation, mucosal bleeding, lethargy/restlessness, postural hypotension, liver enlargement, and progressive increase in hematocrit (i.e., hemoconcentration). […] The critical phase of dengue begins at defervescence and typically lasts 2448 hours.
  • #16 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The 3 phases of dengue fever include febrile, critical, and recovery stages. […] During the febrile phase, individuals typically experience a sudden onset of high-grade fever, reaching approximately 40 C, which usually lasts for 2 to 7 days. […] During the critical phase, defervescence marks a period when the temperature typically decreases to approximately 37.5 to 38 C or lower, occurring between days 3 and 7. This phase is associated with heightened capillary permeability and typically lasts for 1 to 2 days. […] The recovery phase involves the gradual reabsorption of extravascular fluid over 2 to 3 days. […] Expanded dengue virus syndrome refers to unusual or atypical manifestations seen in patients with involvement of various organs such as neurological, hepatic, and renal. […] Symptoms include rapidly rising hematocrit, intense abdominal pain, persistent vomiting, and narrowed or absent blood pressure.
  • #17 Warning signs that your dengue infection is getting worse | gov.sg
    https://www.gov.sg/explainers/warning-signs-that-your-dengue-infection-is-getting-worse
    Feeling nauseous or feverish? Or have a headache that aches from behind the eyes? […] Common symptoms of dengue fever are: Fever, Headache with pain behind the eyes, Muscle and joint aches, Rash, Nausea and vomiting. […] Dengue typically starts off with high fever, accompanied by body aches and pain. The fever typically lasts for 3-5 days. […] The second phase is known as the critical period, and it is the most crucial one to look out for. Your body temperature is coming down (below 38 degrees C), lasting for 48 hours. During this period, your body experiences fluid shifting out of circulation compartments to other body compartments. Fluid may then accumulate in the lungs or abdominal space. Your heart rate, blood pressure may fluctuate, and in severe cases, drop to very low levels that damage your vital organs, such as your kidney and liver.
  • #18 Dengue: Practice Essentials, Background, Pathophysiology
    https://emedicine.medscape.com/article/215840-overview
    Many patients with dengue experience a prodrome of chills; rash, including erythematous mottling of the skin; and facial flushing, which may last 2-3 days. […] Dengue should be suspected in individuals who present with high fever (104F/40C), retro-orbital headache, muscle and joint pain, nausea, lymphadenopathy, vomiting, and rash and who have traveled within 2 weeks of symptom onset to an area where appropriate vectors are present and dengue transmission may be occurring. […] Severe dengue is characterized by severe plasma leakage leading to shock, which is defined by symptoms such as tachycardia, a narrowing of the pulse pressure (a difference in systolic and diastolic pressure less than 20 mmHg), delayed capillary filling, and hypotension. […] The initial phase of severe dengue resembles that of dengue fever and other febrile viral illnesses. Signs of plasma leakage typically appear shortly after the fever breaks, which occurs 3-7 days after symptom onset or sometimes within 24 hours before.
  • #19 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Most patients clinically improve during this phase, but those with substantial plasma leakage can, within a few hours, develop severe dengue. […] Patients with severe plasma leakage may have pleural effusions, ascites, hypoproteinemia, or hemoconcentration. […] Patients may appear to be well despite early signs of shock. However, once hypotension develops, systolic blood pressure rapidly declines, and irreversible shock and death may ensue despite resuscitation. […] Severe dengue is defined by dengue with any of the following clinical manifestations: severe plasma leakage leading to shock or fluid accumulation with respiratory distress; severe bleeding; or severe organ impairment such as hepatitis (elevated transaminases 1,000 IU/L), impaired consciousness, or heart impairment.
  • #20 Warning signs that your dengue infection is getting worse | gov.sg
    https://www.gov.sg/explainers/warning-signs-that-your-dengue-infection-is-getting-worse
    You should look out for these warning signs indicating that the infection is getting worse: Abdominal pain, that is not hunger pangs, Persistent vomiting, even with just fluids, Bleeding tendencies, such as: Blood in your vomit (i.e. red streaks of blood), Bleeding from your nose or gums, Easy bruising, Black and sticky (tar-like) stools, Breathing difficulties. […] After the critical period comes the recovery phase. During this period, fluids that have shifted out of circulation during the critical phase will return to circulation.
  • #21 Dengue fever – UF Health
    https://ufhealth.org/conditions-and-treatments/dengue-fever
    Dengue fever is a virus-caused disease that is spread by mosquitoes. Dengue in its mild form causes fever and a rash and lasts about a week. Severe dengue can cause shock, internal bleeding, and death. About 1 out of 20 people with dengue will develop severe dengue within a few hours after symptoms start. The main risk factor for severe dengue is a prior infection with dengue. […] Dengue fever begins with a sudden high fever, often as high as 105F (40.5C), 4 to 7 days after the infection. […] Symptoms of severe dengue can occur 24 to 48 hours after fever has gone away. Severe symptoms include: Severe stomach pain and tenderness, Vomiting often (at least 3 times in 24 hours), Bleeding from the nose or gums, Vomiting blood or passing blood in the stools or urine, Bleeding under the skin (looks like bruises), Difficulty breathing, rapid breathing, Feeling tired, restless, or irritable.
  • #22 How do You Tell COVID-19 and Dengue Apart?
    https://www.parkwayeast.com.sg/health-plus/article/covid-19-versus-dengue
    Most people who contract dengue or COVID-19 have mild illness and can recover at home, feeling better after a week. […] Some people, however, are at risk of developing severe illness that can be life threatening and requires hospital-based care that is different for the 2 conditions. […] The warning signs for the 2 diseases include: […] Severe dengue: Persistent vomiting, gum (mucosal) bleeding, difficulty breathing, lethargy and restlessness. […] Mild symptoms of a dengue infection include: High fever (40C), Headache, Muscle, bone or joint pain, Nausea and vomiting, Pain behind the eyes, Swollen glands, Rash. […] Most people recover within a week but some may develop severe dengue that can become life-threatening. […] Warning signs of severe dengue fever usually begin within the first 2 days after your fever goes away. They include: Severe stomach pain and persistent vomiting, Bleeding from gums or nose, Blood in urine, stools or vomit, Appearance of bruising on the skin, Difficult or rapid breathing, Fatigue, irritability or restlessness.
  • #23 Dengue Fever (for Parents) | Nemours KidsHealth
    https://kidshealth.org/en/parents/dengue.html
    If dengue hemorrhagic fever is not treated right away, a person can have severe internal bleeding and a drop in blood pressure, and could even die. People with dengue hemorrhagic fever need medical care right away. […] Symptoms of dengue fever can start up to 2 weeks after someone gets infected. Some people infected with the virus won’t have any symptoms. Others will have symptoms for a few days to 2 weeks before getting better. […] Dengue fever usually goes away without causing lasting problems. If someone has severe symptoms, or if symptoms get worse in the first day or two after the fever goes away, get medical care right away. Severe symptoms could be due to dengue hemorrhagic fever, which is a medical emergency.
  • #24 Warning signs that your dengue infection is getting worse | gov.sg
    https://www.gov.sg/explainers/warning-signs-that-your-dengue-infection-is-getting-worse
    You should look out for these warning signs indicating that the infection is getting worse: Abdominal pain, that is not hunger pangs, Persistent vomiting, even with just fluids, Bleeding tendencies, such as: Blood in your vomit (i.e. red streaks of blood), Bleeding from your nose or gums, Easy bruising, Black and sticky (tar-like) stools, Breathing difficulties. […] After the critical period comes the recovery phase. During this period, fluids that have shifted out of circulation during the critical phase will return to circulation.
  • #25 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Most patients clinically improve during this phase, but those with substantial plasma leakage can, within a few hours, develop severe dengue. […] Patients with severe plasma leakage may have pleural effusions, ascites, hypoproteinemia, or hemoconcentration. […] Patients may appear to be well despite early signs of shock. However, once hypotension develops, systolic blood pressure rapidly declines, and irreversible shock and death may ensue despite resuscitation. […] Severe dengue is defined by dengue with any of the following clinical manifestations: severe plasma leakage leading to shock or fluid accumulation with respiratory distress; severe bleeding; or severe organ impairment such as hepatitis (elevated transaminases 1,000 IU/L), impaired consciousness, or heart impairment.
  • #26 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Most patients clinically improve during this phase, but those with substantial plasma leakage can, within a few hours, develop severe dengue. […] Patients with severe plasma leakage may have pleural effusions, ascites, hypoproteinemia, or hemoconcentration. […] Patients may appear to be well despite early signs of shock. However, once hypotension develops, systolic blood pressure rapidly declines, and irreversible shock and death may ensue despite resuscitation. […] Severe dengue is defined by dengue with any of the following clinical manifestations: severe plasma leakage leading to shock or fluid accumulation with respiratory distress; severe bleeding; or severe organ impairment such as hepatitis (elevated transaminases 1,000 IU/L), impaired consciousness, or heart impairment.
  • #27 Dengue: Practice Essentials, Background, Pathophysiology
    https://emedicine.medscape.com/article/215840-overview
    Symptoms indicating impending shock include abdominal pain, vomiting, restlessness, and other signs of circulatory failure such as pallor, tachypnea, dizziness/lightheadedness, and a decreased level of consciousness. […] Severe dengue typically begins with the initial manifestations of dengue fever. The acute febrile illness (temperatures 40C), like that of dengue fever, lasts approximately 2-7 days. However, in persons with severe dengue, the fever reappears, giving a biphasic or saddleback fever curve. […] The critical feature of severe dengue is plasma leakage. Plasma leakage is caused by increased capillary permeability and may manifest as hemoconcentration, as well as pleural effusion and ascites. Bleeding is caused by capillary fragility and thrombocytopenia and may manifest in various forms, ranging from petechial skin hemorrhages to life-threatening gastrointestinal bleeding.
  • #28 Dengue fever – UF Health
    https://ufhealth.org/conditions-and-treatments/dengue-fever
    Dengue fever is a virus-caused disease that is spread by mosquitoes. Dengue in its mild form causes fever and a rash and lasts about a week. Severe dengue can cause shock, internal bleeding, and death. About 1 out of 20 people with dengue will develop severe dengue within a few hours after symptoms start. The main risk factor for severe dengue is a prior infection with dengue. […] Dengue fever begins with a sudden high fever, often as high as 105F (40.5C), 4 to 7 days after the infection. […] Symptoms of severe dengue can occur 24 to 48 hours after fever has gone away. Severe symptoms include: Severe stomach pain and tenderness, Vomiting often (at least 3 times in 24 hours), Bleeding from the nose or gums, Vomiting blood or passing blood in the stools or urine, Bleeding under the skin (looks like bruises), Difficulty breathing, rapid breathing, Feeling tired, restless, or irritable.
  • #29 Symptoms, transmission, and current treatments for dengue | DNDi
    https://dndi.org/diseases/dengue/facts/
    Dengue symptoms range from none to serious flu-like symptoms. A small proportion of people develop severe dengue, which can be fatal. […] Dengue can have no symptoms or cause only mild illness, but it can also cause flu-like symptoms such as: high fever (40C/104F), severe headache, pain behind the eyes, nausea, vomiting, swollen glands, rash, muscle, joint, or bone pains so severe that dengue is sometimes referred to as breakbone fever. […] Severe dengue happens when blood vessels become damaged and leaky, and the number of platelets (cells which form clots) drops. As a result, severe dengue can cause shock, internal bleeding, bleeding gums or nose, organ failure, and death. The symptoms of severe dengue include: severe abdominal pain, persistent vomiting, rapid breathing, bleeding gums or nose, fatigue, restlessness, liver enlargement, blood in vomit or stool, potentially fatal. […] The lack of treatment options increases the risk of people developing severe dengue, which is potentially fatal. […] Dengue-specific treatments are needed to treat the disease at different stages and to reduce the risk of an infection progressing to severe disease.
  • #30 Symptoms of Dengue and Testing | Dengue | CDC
    https://www.cdc.gov/dengue/signs-symptoms/index.html
    The most common symptom of dengue is fever with any of the following: […] For people who get sick with dengue, symptoms can be mild or severe. […] Severe dengue can be life-threatening within a few hours and often requires care at a hospital. […] Symptoms of dengue typically last 27 days. […] Most people will recover after about a week. […] Symptoms of dengue can become severe within a few hours. Severe dengue is a medical emergency. […] About 1 in 20 people who get sick with dengue will develop severe dengue. Severe dengue can result in shock, internal bleeding, and death. […] Watch for warning of severe dengue. Warning signs usually begin in the 24-48 hours after fever has gone away.
  • #31 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The 3 phases of dengue fever include febrile, critical, and recovery stages. […] During the febrile phase, individuals typically experience a sudden onset of high-grade fever, reaching approximately 40 C, which usually lasts for 2 to 7 days. […] During the critical phase, defervescence marks a period when the temperature typically decreases to approximately 37.5 to 38 C or lower, occurring between days 3 and 7. This phase is associated with heightened capillary permeability and typically lasts for 1 to 2 days. […] The recovery phase involves the gradual reabsorption of extravascular fluid over 2 to 3 days. […] Expanded dengue virus syndrome refers to unusual or atypical manifestations seen in patients with involvement of various organs such as neurological, hepatic, and renal. […] Symptoms include rapidly rising hematocrit, intense abdominal pain, persistent vomiting, and narrowed or absent blood pressure.
  • #32 Warning signs that your dengue infection is getting worse | gov.sg
    https://www.gov.sg/explainers/warning-signs-that-your-dengue-infection-is-getting-worse
    You should look out for these warning signs indicating that the infection is getting worse: Abdominal pain, that is not hunger pangs, Persistent vomiting, even with just fluids, Bleeding tendencies, such as: Blood in your vomit (i.e. red streaks of blood), Bleeding from your nose or gums, Easy bruising, Black and sticky (tar-like) stools, Breathing difficulties. […] After the critical period comes the recovery phase. During this period, fluids that have shifted out of circulation during the critical phase will return to circulation.
  • #33 Dengue fever – Causes, Symptoms, treatments, how long does it last? | MedPark Hospital
    https://www.medparkhospital.com/en-US/disease-and-treatment/dengue-fever
    The recovery phase is the final stage of dengue fever. Individuals who have passed the febrile phase without entering the critical phase, or those who have recovered from the critical second phase for 1-2 days, will reach the recovery phase. During this phase, the body gradually recovers, and various symptoms of dengue fever gradually improve. […] The severity of dengue fever symptoms tends to increase with each subsequent infection, such as during the second, third, or fourth dengue infection. […] In cases where individuals experience persistent high fever, prolonged vomiting, intense abdominal pain, rapid heartbeat, decreased urine output, restlessness, extreme fatigue, and lethargy, seeking immediate medical attention from a qualified healthcare professional at a hospital is imperative.
  • #34 Dengue virus infection: Clinical manifestations and diagnosis – UpToDate
    https://www.uptodate.com/contents/dengue-virus-infection-clinical-manifestations-and-diagnosis
    Dengue is a febrile illness caused by infection with one of four dengue viruses (DENV) transmitted by Aedes aegypti or Aedes albopictus mosquitoes during the taking of a blood meal. Infection may be asymptomatic or present with a broad range of clinical manifestations including a mild febrile illness to a life-threatening shock syndrome. […] The incubation period of DENV infection ranges from 3 to 14 days; symptoms typically develop between 4 and 7 days after the bite of an infected mosquito. […] There are three phases that can be seen in the setting of DENV infection: a febrile phase, a critical phase, and a recovery phase; however, the critical phase is not seen in all categories of infection. […] The febrile phase of DENV infection is characterized by sudden high-grade fever (≥38.5°C) accompanied by headache, vomiting, myalgia, arthralgia, retro-orbital pain, hemorrhagic manifestations, and a transient macular rash in some cases. […] The critical phase lasts for 24 to 48 hours. […] During the recovery phase, plasma leakage and hemorrhage resolve, vital signs stabilize, and accumulated fluids are resorbed.
  • #35 Dengue fever – Causes, Symptoms, treatments, how long does it last? | MedPark Hospital
    https://www.medparkhospital.com/en-US/disease-and-treatment/dengue-fever
    The recovery phase is the final stage of dengue fever. Individuals who have passed the febrile phase without entering the critical phase, or those who have recovered from the critical second phase for 1-2 days, will reach the recovery phase. During this phase, the body gradually recovers, and various symptoms of dengue fever gradually improve. […] The severity of dengue fever symptoms tends to increase with each subsequent infection, such as during the second, third, or fourth dengue infection. […] In cases where individuals experience persistent high fever, prolonged vomiting, intense abdominal pain, rapid heartbeat, decreased urine output, restlessness, extreme fatigue, and lethargy, seeking immediate medical attention from a qualified healthcare professional at a hospital is imperative.
  • #36 3 Phases of Dengue Fever: When to Be Alert? – EMC Healthcare – SAME
    https://www.emc.id/en/care-plus/3-phases-of-dengue-fever-when-to-be-alert
    If not treated properly, this phase can develop into dengue shock, which can potentially lead to organ failure and even death. Therefore, if you or someone close to you experiences these signs, seek medical attention immediately. […] If the patient successfully passes the critical phase, they will enter the recovery phase which lasts about 48 to 72 hours. In this phase, the blood vessel leakage begins to improve, lost body fluids return to circulation, and the patient’s condition slowly improves. […] Patients who enter this phase will experience increased appetite, a more energetic body, and more frequent urination. However, it is important to continue to pay attention to hydration and nutritional intake so that the recovery process is optimal. […] You need to seek medical help immediately if you experience the following symptoms:
  • #37 3 Phases of Dengue Fever: When to Be Alert? – EMC Healthcare – SAME
    https://www.emc.id/en/care-plus/3-phases-of-dengue-fever-when-to-be-alert
    If not treated properly, this phase can develop into dengue shock, which can potentially lead to organ failure and even death. Therefore, if you or someone close to you experiences these signs, seek medical attention immediately. […] If the patient successfully passes the critical phase, they will enter the recovery phase which lasts about 48 to 72 hours. In this phase, the blood vessel leakage begins to improve, lost body fluids return to circulation, and the patient’s condition slowly improves. […] Patients who enter this phase will experience increased appetite, a more energetic body, and more frequent urination. However, it is important to continue to pay attention to hydration and nutritional intake so that the recovery process is optimal. […] You need to seek medical help immediately if you experience the following symptoms:
  • #38 How Many Days Does Dengue Fever Last?
    https://redcliffelabs.com/myhealth/fever/how-many-days-does-dengue-fever-last/
    Critical phase of dengue fever: It is the second stage of dengue fever that occurs around 3-7 days after the febrile phase. Some symptoms may include: Bleeding gums or nose, Pale and cold skin, Persistent vomiting, Rapid breathing, Being very thirsty, Severe abdominal pain, Fatigue, Restlessness, Weakness, Heavy menstruation and bleeding for a prolonged time. […] Recovery Stage: This is the final stage of dengue fever, in which the body gradually recovers. The signs of the recovery or final phase include: Overall improvement, The body temperature returns to normal, Normal blood pressure and pulse rate, Improved appetite, It begins to produce a lot of urine, An enlarged liver begins to shrink within 1-2 weeks. […] People with severe dengue symptoms should seek medical attention immediately. […] According to the World Health Organization (WHO), dengue can be classified into dengue without and with symptoms, including vomiting, abdominal pain, difficulty breathing, lethargy, and fluid imbalances. Consult your healthcare provider if you have dengue fever and the symptoms last 3 to 7 days.
  • #39 Understanding Dengue Fever | Saint Luke’s Health System
    https://www.saintlukeskc.org/health-library/understanding-dengue-fever
    Mild dengue infection may have few symptoms. Moderate to severe dengue has 3 phases: febrile, critical, and recovery. […] Symptoms of the febrile phase last 3 to 7 days and include: Sudden high fever, Skin redness or red patches on the skin, Severe headache, Pain behind the eyes, Severe joint and muscle pain, Upset stomach (nausea), Vomiting, Easy bruising and bleeding. […] The critical phase often lasts 2 to 3 days. During this time, body temperature may return to normal. Symptoms of the critical phase include: Vomiting that wont stop, Severe pain in the belly (abdomen), Fluid in the chest and belly, Fast breathing, Low blood pressure, Bleeding. […] A person with severe dengue may have trouble breathing, severe bleeding, damage to organs, or dengue shock syndrome. This can be fatal, and is a medical emergency. […] During the recovery phase, there is overall improvement. There may also be a rash and itchy skin. There may be heart and lung problems.
  • #40 Dengue Fever – Symptoms, Causes, Diagnosis and Treatment PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact Number f
    https://www.pacehospital.com/dengue-fever-causes-symptoms-and-treatments
    The patient may develop dengue hemorrhagic fever symptoms that include pain in the abdomen, persistent vomiting, change in body temperature from fever to hypothermia, irritability, confusion, and hemorrhagic manifestations. The patient might show early signs of shock, including weak pulse, restlessness, and cold clammy skin. […] Dengue shock syndrome is a serious complication of dengue infection that has a high death rate. Secondary infection with a different viral serotype causes severe dengue. […] The signs of dengue fever typically last for 2–7 days. Most people will recover after about a week. However, some people may develop severe dengue, which can be life-threatening. […] In most cases, the platelet count in dengue will increase around day 7 of the illness. However, the platelet count can take up to 10 days to return to normal. Sometimes, the platelet count may not return to normal even after ten days.
  • #41 How Many Days Does Dengue Fever Last?
    https://redcliffelabs.com/myhealth/fever/how-many-days-does-dengue-fever-last/
    Critical phase of dengue fever: It is the second stage of dengue fever that occurs around 3-7 days after the febrile phase. Some symptoms may include: Bleeding gums or nose, Pale and cold skin, Persistent vomiting, Rapid breathing, Being very thirsty, Severe abdominal pain, Fatigue, Restlessness, Weakness, Heavy menstruation and bleeding for a prolonged time. […] Recovery Stage: This is the final stage of dengue fever, in which the body gradually recovers. The signs of the recovery or final phase include: Overall improvement, The body temperature returns to normal, Normal blood pressure and pulse rate, Improved appetite, It begins to produce a lot of urine, An enlarged liver begins to shrink within 1-2 weeks. […] People with severe dengue symptoms should seek medical attention immediately. […] According to the World Health Organization (WHO), dengue can be classified into dengue without and with symptoms, including vomiting, abdominal pain, difficulty breathing, lethargy, and fluid imbalances. Consult your healthcare provider if you have dengue fever and the symptoms last 3 to 7 days.
  • #42
    https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue
    Most people who get dengue will not have symptoms. But for those who do, the most common symptoms are high fever, headache, body aches, nausea, and rash. Most will get better in 12 weeks. Some people develop severe dengue and need care in a hospital. […] In severe cases, dengue can be fatal. […] Most people with dengue have mild or no symptoms and will get better in 12 weeks. Rarely, dengue can be severe and lead to death. […] If symptoms occur, they usually begin 4-10 days after infection and last for 2-7 days. Symptoms may include: high fever (40C/104F), severe headache, pain behind the eyes, muscle and joint pains, nausea, vomiting, swollen glands, rash. […] Individuals who are infected for the second time are at greater risk of severe dengue. […] Severe dengue symptoms often come after the fever has gone away: severe abdominal pain, persistent vomiting, rapid breathing, bleeding gums or nose, fatigue, restlessness, blood in vomit or stool, being very thirsty, pale and cold skin, feeling weak. […] People with these severe symptoms should get care right away. […] After recovery, people who have had dengue may feel tired for several weeks.
  • #43 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Dengue fever symptoms start to appear four to 10 days after a mosquito bite and can last three to seven days. About 1 in 20 people sick with dengue will develop severe dengue after their initial symptoms begin to fade. […] Severe dengue is a life-threatening worsening of dengue symptoms. Warning signs of severe dengue are usually seen 24 to 48 hours after your fever goes away. […] Severe dengue is a medical emergency that can be fatal. If you have dengue or live in an area where dengue is common, go to the nearest ER immediately if you experience any of these symptoms: Stomach/abdominal pain. Frequent vomiting. Throwing up blood or blood in your poop (stool). Nose bleeds or bleeding gums. Extreme tiredness, restlessness or irritability. […] Initial symptoms of dengue last three to seven days. Most people begin to feel better after this, but some have life-threatening severe dengue that requires treatment in a medical facility.
  • #44 Symptoms of Dengue and Testing | Dengue | CDC
    https://www.cdc.gov/dengue/signs-symptoms/index.html
    The most common symptom of dengue is fever with any of the following: […] For people who get sick with dengue, symptoms can be mild or severe. […] Severe dengue can be life-threatening within a few hours and often requires care at a hospital. […] Symptoms of dengue typically last 27 days. […] Most people will recover after about a week. […] Symptoms of dengue can become severe within a few hours. Severe dengue is a medical emergency. […] About 1 in 20 people who get sick with dengue will develop severe dengue. Severe dengue can result in shock, internal bleeding, and death. […] Watch for warning of severe dengue. Warning signs usually begin in the 24-48 hours after fever has gone away.
  • #45 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Most patients clinically improve during this phase, but those with substantial plasma leakage can, within a few hours, develop severe dengue. […] Patients with severe plasma leakage may have pleural effusions, ascites, hypoproteinemia, or hemoconcentration. […] Patients may appear to be well despite early signs of shock. However, once hypotension develops, systolic blood pressure rapidly declines, and irreversible shock and death may ensue despite resuscitation. […] Severe dengue is defined by dengue with any of the following clinical manifestations: severe plasma leakage leading to shock or fluid accumulation with respiratory distress; severe bleeding; or severe organ impairment such as hepatitis (elevated transaminases 1,000 IU/L), impaired consciousness, or heart impairment.
  • #46 Dengue: Symptoms, Prevention and Treatments – PAHO/WHO
    https://www.paho.org/en/topics/dengue
    The patient may present intense and continuous abdominal pain, persistent vomiting, fluid accumulation, mucosal bleeding, altered consciousness, hepatomegaly and progressive increase in hematocrit. […] Severe forms of dengue are defined by one or more of the following: (i) shock from plasma leakage, fluid accumulation with respiratory distress, or both; (ii) profuse bleeding that is considered clinically important by treating physicians, or (iii) severe organ involvement.
  • #47
    https://www.who.int/news-room/questions-and-answers/item/dengue-and-severe-dengue
    Dengue causes flu-like symptoms and lasts for 2-7 days. Dengue fever usually occurs after an incubation period of 4-10 days after the bite of the infected mosquito. […] High Fever (40 C/104 F) is usually accompanied by at least two of the following symptoms: headaches, pain behind eyes, nausea, vomiting, swollen glands, joint, bone or muscle pains, rash. […] Individuals infected for the second time are at greater risk of severe dengue. When developing into severe dengue, the critical phase takes place around 3-7 days after the first sign of illness. […] On the other hand, special attention needs to be given to these warning signs as it could lead to severe dengue: severe abdominal pain, persistent vomiting, bleeding gums, rapid breathing, fatigue/restlessness, blood in vomit or stool, being very thirsty, pale and cold skin. […] Severe dengue can cause: plasma leaking that may lead to shock and/or fluid accumulation with/without respiratory distress; severe bleeding; and severe organ impairment. […] For people with severe dengue, hospitalization is often needed.
  • #48 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Dengue fever symptoms start to appear four to 10 days after a mosquito bite and can last three to seven days. About 1 in 20 people sick with dengue will develop severe dengue after their initial symptoms begin to fade. […] Severe dengue is a life-threatening worsening of dengue symptoms. Warning signs of severe dengue are usually seen 24 to 48 hours after your fever goes away. […] Severe dengue is a medical emergency that can be fatal. If you have dengue or live in an area where dengue is common, go to the nearest ER immediately if you experience any of these symptoms: Stomach/abdominal pain. Frequent vomiting. Throwing up blood or blood in your poop (stool). Nose bleeds or bleeding gums. Extreme tiredness, restlessness or irritability. […] Initial symptoms of dengue last three to seven days. Most people begin to feel better after this, but some have life-threatening severe dengue that requires treatment in a medical facility.
  • #49 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The disease is classified as either dengue or severe dengue. […] Severe dengue is characterized by dengue fever accompanied by severe plasma leakage, hemorrhage, impaired consciousness, myocardial dysfunction, pulmonary dysfunction, and organ dysfunction, including transaminitis greater than 1000 IU/L. […] The treatment approach for dengue fever varies depending on the patient’s illness phase. Patients without warning signs can typically be treated as outpatients with acetaminophen and sufficient oral fluids. […] Patients presenting with warning signs of the disease, severe dengue fever, or having risk factors such as age, pregnancy status, diabetes mellitus, or those who are living alone should be evaluated for hospitalization.
  • #50 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Most patients clinically improve during this phase, but those with substantial plasma leakage can, within a few hours, develop severe dengue. […] Patients with severe plasma leakage may have pleural effusions, ascites, hypoproteinemia, or hemoconcentration. […] Patients may appear to be well despite early signs of shock. However, once hypotension develops, systolic blood pressure rapidly declines, and irreversible shock and death may ensue despite resuscitation. […] Severe dengue is defined by dengue with any of the following clinical manifestations: severe plasma leakage leading to shock or fluid accumulation with respiratory distress; severe bleeding; or severe organ impairment such as hepatitis (elevated transaminases 1,000 IU/L), impaired consciousness, or heart impairment.
  • #51 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Most patients clinically improve during this phase, but those with substantial plasma leakage can, within a few hours, develop severe dengue. […] Patients with severe plasma leakage may have pleural effusions, ascites, hypoproteinemia, or hemoconcentration. […] Patients may appear to be well despite early signs of shock. However, once hypotension develops, systolic blood pressure rapidly declines, and irreversible shock and death may ensue despite resuscitation. […] Severe dengue is defined by dengue with any of the following clinical manifestations: severe plasma leakage leading to shock or fluid accumulation with respiratory distress; severe bleeding; or severe organ impairment such as hepatitis (elevated transaminases 1,000 IU/L), impaired consciousness, or heart impairment.
  • #52 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The 3 phases of dengue fever include febrile, critical, and recovery stages. […] During the febrile phase, individuals typically experience a sudden onset of high-grade fever, reaching approximately 40 C, which usually lasts for 2 to 7 days. […] During the critical phase, defervescence marks a period when the temperature typically decreases to approximately 37.5 to 38 C or lower, occurring between days 3 and 7. This phase is associated with heightened capillary permeability and typically lasts for 1 to 2 days. […] The recovery phase involves the gradual reabsorption of extravascular fluid over 2 to 3 days. […] Expanded dengue virus syndrome refers to unusual or atypical manifestations seen in patients with involvement of various organs such as neurological, hepatic, and renal. […] Symptoms include rapidly rising hematocrit, intense abdominal pain, persistent vomiting, and narrowed or absent blood pressure.
  • #53 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The disease is classified as either dengue or severe dengue. […] Severe dengue is characterized by dengue fever accompanied by severe plasma leakage, hemorrhage, impaired consciousness, myocardial dysfunction, pulmonary dysfunction, and organ dysfunction, including transaminitis greater than 1000 IU/L. […] The treatment approach for dengue fever varies depending on the patient’s illness phase. Patients without warning signs can typically be treated as outpatients with acetaminophen and sufficient oral fluids. […] Patients presenting with warning signs of the disease, severe dengue fever, or having risk factors such as age, pregnancy status, diabetes mellitus, or those who are living alone should be evaluated for hospitalization.
  • #54 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #55 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #56 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #57 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #58 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Dengue fever symptoms start to appear four to 10 days after a mosquito bite and can last three to seven days. About 1 in 20 people sick with dengue will develop severe dengue after their initial symptoms begin to fade. […] Severe dengue is a life-threatening worsening of dengue symptoms. Warning signs of severe dengue are usually seen 24 to 48 hours after your fever goes away. […] Severe dengue is a medical emergency that can be fatal. If you have dengue or live in an area where dengue is common, go to the nearest ER immediately if you experience any of these symptoms: Stomach/abdominal pain. Frequent vomiting. Throwing up blood or blood in your poop (stool). Nose bleeds or bleeding gums. Extreme tiredness, restlessness or irritability. […] Initial symptoms of dengue last three to seven days. Most people begin to feel better after this, but some have life-threatening severe dengue that requires treatment in a medical facility.
  • #59 Symptoms of Dengue and Testing | Dengue | CDC
    https://www.cdc.gov/dengue/signs-symptoms/index.html
    The most common symptom of dengue is fever with any of the following: […] For people who get sick with dengue, symptoms can be mild or severe. […] Severe dengue can be life-threatening within a few hours and often requires care at a hospital. […] Symptoms of dengue typically last 27 days. […] Most people will recover after about a week. […] Symptoms of dengue can become severe within a few hours. Severe dengue is a medical emergency. […] About 1 in 20 people who get sick with dengue will develop severe dengue. Severe dengue can result in shock, internal bleeding, and death. […] Watch for warning of severe dengue. Warning signs usually begin in the 24-48 hours after fever has gone away.
  • #60 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Most people recover from dengue fever without any lasting complications. If you have symptoms of dengue fever, you have about a 1 in 20 chance of it worsening to severe dengue. If you have severe dengue and are treated immediately at a hospital or medical facility, you have a greater than 99% chance of recovering. […] Yes. Because there are at least four versions (strains) of the dengue virus, you can get dengue more than once. You’ll usually become immune to the first strain you get sick with and cant get it again. But you can get sick with one of the other three strains after that. In fact, you’re more likely to get severely sick if you get dengue more than once.
  • #61 3 phases of Dengue hemorrhagic fever | Vinmec
    https://www.vinmec.com/eng/blog/3-stages-of-development-of-dengue-fever-en
    Recovery Phase: Fever subsides for more than 48 hours, patients feel less tired, generally improved, have an increase in appetite, and urinate more frequently. Platelet counts begin to increase. […] Dengue fever progresses through three stages, with the most dangerous period occurring between the third and seventh days, when complications can arise and be life-threatening. Early recognition of symptoms and seeking medical attention at a reputable healthcare facility for diagnosis, treatment, and monitoring of potential complications is crucial.
  • #62 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Most people recover from dengue fever without any lasting complications. If you have symptoms of dengue fever, you have about a 1 in 20 chance of it worsening to severe dengue. If you have severe dengue and are treated immediately at a hospital or medical facility, you have a greater than 99% chance of recovering. […] Yes. Because there are at least four versions (strains) of the dengue virus, you can get dengue more than once. You’ll usually become immune to the first strain you get sick with and cant get it again. But you can get sick with one of the other three strains after that. In fact, you’re more likely to get severely sick if you get dengue more than once.
  • #63 Dengue Fever: Symptoms, Treatment, and Prevention
    https://patient.info/travel-and-vaccinations/dengue-leaflet
    People living with severe dengue are very sick, with shock, collapse and, often, bleeding. The symptoms seen in dengue with warning signs may occur and may be more severe. […] Severe dengue is a life-threatening illness. […] Severe dengue normally occurs only with a second attack of dengue caused by a different strain of dengue virus to your previous attack. […] The symptoms of dengue are mainly caused by our own immune systems responding to the virus. In the case of severe dengue the immune system responds dramatically, producing destructive substances which damage organs and make fluid leak from blood vessels. […] Most cases of dengue end with a 'recovery phase’. Patients are often very itchy, and where there has been a rash the skin may peel. […] Patients with severe dengue can quickly become severely unwell – close monitoring is needed.
  • #64 Dengue Clinical Presentation: History, Physical Examination
    https://emedicine.medscape.com/article/215840-clinical
    Recovery is complete but slow, with fatigue and exhaustion often persisting after the fever has subsided. The convalescent phase may last for 2 weeks. […] Patients are at risk for development of dengue hemorrhagic fever or dengue shock syndrome at approximately the time of defervescence. Abdominal pain in conjunction with restlessness, change in mental status, hypothermia, and a drop in the platelet count presages the development of dengue hemorrhagic fever. […] Of patients with dengue hemorrhagic fever, 90% are younger than 15 years. The initial phase of dengue hemorrhagic fever is similar to that of dengue fever and other febrile viral illnesses. Shortly after the fever breaks (or sometimes within 24 hours before), signs of plasma leakage appear, along with the development of hemorrhagic symptoms such as bleeding from sites of trauma, gastrointestinal bleeding, and hematuria. Patients may also present with abdominal pain, vomiting, febrile seizures (in children), and a decreased level of consciousness. […] If left untreated, dengue hemorrhagic fever most likely progresses to dengue shock syndrome. Common symptoms in impending shock include abdominal pain, vomiting, and restlessness. Patients also may have symptoms related to circulatory failure.
  • #65 It’s Not ‘Just Dengue’ When It Lasts For Months – CodeBlue
    https://vgh.pth.mybluehost.me/2024/09/its-not-just-dengue-when-it-lasts-for-months/
    Post dengue syndrome can severely affect a persons quality of life, and the experience can cause a person to get depressed, especially those who had expected that their experience with dengue would be mild. […] Simply put, Dr Shanthi draws similarities between PDS and a tsunami even though the attack has come and gone, the damage has been done, leaving behind chronic inflammation and an immune system that has become highly activated. […] Overall, Dr Shanthi said that elderly patients and those with comorbid conditions like hypertension, ischemic heart disease, obesity and autoimmune disease are more likely to experience severe dengue, which increases the likelihood of experiencing post-dengue syndrome. […] Among these, the elderly are also more likely to require high-dependency or intensive care as their health can deteriorate more quickly, with symptoms that linger for a longer period.
  • #66 Dengue: Symptoms, Duration and Treatment of This Global Epidemic – Blog – ISGLOBAL
    https://www.isglobal.org/en/healthisglobal/-/custom-blog-portlet/dengue-fever-a-global-epidemic-explained
    Dengue usually lasts between 2 and 7 days. About 1 in 20 people with the disease may develop severe dengue, which can be fatal if not treated promptly. Between 2% and 5% of people with severe dengue may die. Without treatment, mortality from severe dengue can reach 50%. […] The most common symptoms are fever, rash, pain (including pain behind the eyes), and intense joint pain. However, not everyone develops symptoms. […] Symptoms of severe dengue include bleeding from the nose or gums, vomiting, breathing difficulty, low blood pressure, and organ failure. […] In severe cases, it can progress rapidly and become life-threatening if not treated promptly. […] People previously infected with one serotype develop immunity to that serotype but are more likely to develop severe dengue if they are later infected with a different serotype, because existing antibodies help the virus enter cells (a phenomenon known as antibody-dependent enhancement or ADE). Infants and pregnant women are also at greater risk of severe dengue.
  • #67 It’s Not ‘Just Dengue’ When It Lasts For Months – CodeBlue
    https://vgh.pth.mybluehost.me/2024/09/its-not-just-dengue-when-it-lasts-for-months/
    Post dengue syndrome can severely affect a persons quality of life, and the experience can cause a person to get depressed, especially those who had expected that their experience with dengue would be mild. […] Simply put, Dr Shanthi draws similarities between PDS and a tsunami even though the attack has come and gone, the damage has been done, leaving behind chronic inflammation and an immune system that has become highly activated. […] Overall, Dr Shanthi said that elderly patients and those with comorbid conditions like hypertension, ischemic heart disease, obesity and autoimmune disease are more likely to experience severe dengue, which increases the likelihood of experiencing post-dengue syndrome. […] Among these, the elderly are also more likely to require high-dependency or intensive care as their health can deteriorate more quickly, with symptoms that linger for a longer period.
  • #68 Burden of Postinfectious Symptoms after Acute Dengue, Vietnam
    https://pmc.ncbi.nlm.nih.gov/articles/PMC9796196/
    Dengue is a mosquitoborne viral infection found across much of the tropical and subtropical world. Most infections are asymptomatic or paucisymptomatic. Acute symptoms range from an influenza-like self-limited febrile illness to, in a small proportion of cases, severe and complicated disease that can prove fatal. The symptoms of acute dengue are generally understood to resolve after 12 weeks, but the potential for persistent or delayed symptoms has received increasing attention in recent years. However, few formal studies have been published, and these studies have reported a range of symptoms and frequencies. A recent review summarizing this literature showed a substantial proportion of persons experienced some kind of postacute symptoms; the proportion decreased over time after infection, and 24% reported notable fatigue.
  • #69 It’s Not ‘Just Dengue’ When It Lasts For Months – CodeBlue
    https://vgh.pth.mybluehost.me/2024/09/its-not-just-dengue-when-it-lasts-for-months/
    Severe dengue can take a heavy toll on your health, and some suffer even more with post-dengue syndrome that can linger for months or more. […] However, our nationwide cumulative dengue cases stood at 83,131 as of July 20, 2024. […] the consequences can be dire as patients with severe dengue often require hospitalisation and face higher likelihood of internal bleeding, plasma leakage, organ damage, respiratory problems and even death. […] This recognised but lesser-known phenomenon is known as post-dengue syndrome. […] Bahwanees experience is known as post-dengue syndrome, which is the clinical manifestation of dengue fever that persists for more than six weeks after the acute phase is over, explained Dr Shanthi Ratnam, consultant physician and intensivist. […] Those who experience post-dengue syndrome (PDS) are likely to have symptoms such as fatigue that can range from mild to overwhelming; musculoskeletal symptoms like muscle and joint pain or swelling of the joints known as reactive arthritis; and neurological signs like poor concentration or dizziness.
  • #70 Understanding the Long-Term Impact of Dengue Fever on Health
    https://www.aksharhospitals.com/blog/long-term-effects-of-dengue-fever
    Post-Dengue Syndrome refers to a cluster of symptoms that persist even after the acute phase of dengue fever has resolved. […] These symptoms may include extreme fatigue, muscle and joint pain, depression, and cognitive impairment. PDS can significantly impact an individual’s quality of life. […] One of the primary symptoms of Post-Dengue Syndrome is persistent fatigue and weakness. […] Even after the acute phase of dengue fever has passed, individuals may continue to experience overwhelming exhaustion. […] Dengue-related arthralgia, characterized by persistent joint and muscle pain, can significantly impact individuals recovering from dengue fever. […] Neurological symptoms are common in individuals experiencing Post-Dengue Syndrome. […] These may include recurrent headaches, cognitive impairment, and mood changes.
  • #71 SciELO Brazil – Prospective study of patients with persistent symptoms of dengue in Brazil Prospective study of patients with persistent symptoms of dengue in Brazil
    https://www.scielo.br/j/rimtsp/a/httsy4QtybkxsGmVdCcRGvR/?lang=en
    Dengue is an arboviral infection clinically recognized as an acute and self-limited disease. Persistence of dengue symptoms is known, but it has been little studied. Symptoms that persisted for more than 14 days were observed in 61 (54.0%) patients, and six (6.2%) of them had symptoms for 6 months or more. The persistent symptoms identified were myalgia, weakness, hair loss, memory loss, reduced resistance to physical effort, headache, reasoning problems, arthralgia, sleepiness- and emotional lability. […] The progression to persistent symptoms was significantly associated with hospitalization, older age, more severe disease, the presence of bleeding and comorbidities upon univariate analysis. Upon multivariate analysis, the presence of persistent symptoms continued to be significantly associated only with increased age and dengue with warning signs. […] In conclusion, the frequency of progression to persistent symptoms in dengue is relevant in patients seen at a tertiary hospital and the persistence of symptoms is more common in patients with dengue with warning signs.
  • #72
    https://journals.lww.com/aptm/fulltext/2019/12060/symptoms_of_dengue_at_the_acute_and_post_infection.3.aspx
    The most common symptoms of dengue fever at the acute stage was body ache (81.81%, n=387), followed by headache (71.67%, n=339), loss of appetite (66.80%, n=316), tiredness (53.06 %, n=251) and vomiting (41.86%, n=198). […] The most common symptom during the post-infection stage was body ache (48.62%, n=230), followed by fatigue (39.74%, n=188), and loss of appetite (28.75%, n=136). […] The most common symptoms of dengue fever during acute stage were body ache (myalgia/arthralgia) (81.81%), followed by headache (71.67%), loss of appetite (66.80%), fatigue (53.07%) and vomiting (41.86%). […] The most common symptoms during the post-infection stage were body ache (48.63%), followed by fatigue (39.74%), and loss of appetite (28.75%). […] At least one symptom appeared for 79.70% (n=377) of patients during the post-infection period. […] The study shows a prolonged persistence of clinical symptoms during the postinfection period. […] Persistent clinical symptoms during post-infection period is evident.
  • #73
    https://journals.lww.com/aptm/fulltext/2019/12060/symptoms_of_dengue_at_the_acute_and_post_infection.3.aspx
    The most common symptoms of dengue fever at the acute stage was body ache (81.81%, n=387), followed by headache (71.67%, n=339), loss of appetite (66.80%, n=316), tiredness (53.06 %, n=251) and vomiting (41.86%, n=198). […] The most common symptom during the post-infection stage was body ache (48.62%, n=230), followed by fatigue (39.74%, n=188), and loss of appetite (28.75%, n=136). […] The most common symptoms of dengue fever during acute stage were body ache (myalgia/arthralgia) (81.81%), followed by headache (71.67%), loss of appetite (66.80%), fatigue (53.07%) and vomiting (41.86%). […] The most common symptoms during the post-infection stage were body ache (48.63%), followed by fatigue (39.74%), and loss of appetite (28.75%). […] At least one symptom appeared for 79.70% (n=377) of patients during the post-infection period. […] The study shows a prolonged persistence of clinical symptoms during the postinfection period. […] Persistent clinical symptoms during post-infection period is evident.
  • #74 Burden of Postinfectious Symptoms after Acute Dengue, Vietnam
    https://pmc.ncbi.nlm.nih.gov/articles/PMC9796196/
    We report on postinfectious symptoms in 247 predominantly pediatric patients from Vietnam 3 months after an acute febrile illness; 200 of them had dengue. After acute dengue, we observed a broad spectrum of postviral symptoms ranging from fatigue, joint pain, and muscle pain to vision problems and hair loss. We report 8% patients experienced fatigue, consistent with a study in Singapore reporting 9%, but lower than the 24% in another Singapore study and the 28% reported from Cuba. Our estimate of 47% of persons experiencing 1 symptom is higher than the 8.5% observed in Peru but lower than the 65% experiencing 1 persistent symptom observed in Brazil. […] The alopecia we report in our study has been observed previously, at a much lower rate in 1 study in Brazil and at a similar rate in a recent study from Mexico. Alopecia after dengue has been noted in 1 case report. Vision problems associated with dengue have previously been reported but mainly during the acute phase or soon afterwards. In our study, we saw that these symptoms can persist for several months or start much later after infection, which was also seen in the recent study in Mexico.
  • #75 Burden of Postinfectious Symptoms after Acute Dengue, Vietnam
    https://pmc.ncbi.nlm.nih.gov/articles/PMC9796196/
    We report on postinfectious symptoms in 247 predominantly pediatric patients from Vietnam 3 months after an acute febrile illness; 200 of them had dengue. After acute dengue, we observed a broad spectrum of postviral symptoms ranging from fatigue, joint pain, and muscle pain to vision problems and hair loss. We report 8% patients experienced fatigue, consistent with a study in Singapore reporting 9%, but lower than the 24% in another Singapore study and the 28% reported from Cuba. Our estimate of 47% of persons experiencing 1 symptom is higher than the 8.5% observed in Peru but lower than the 65% experiencing 1 persistent symptom observed in Brazil. […] The alopecia we report in our study has been observed previously, at a much lower rate in 1 study in Brazil and at a similar rate in a recent study from Mexico. Alopecia after dengue has been noted in 1 case report. Vision problems associated with dengue have previously been reported but mainly during the acute phase or soon afterwards. In our study, we saw that these symptoms can persist for several months or start much later after infection, which was also seen in the recent study in Mexico.
  • #76 Understanding the Long-Term Impact of Dengue Fever on Health
    https://www.aksharhospitals.com/blog/long-term-effects-of-dengue-fever
    Post-Dengue Syndrome refers to a cluster of symptoms that persist even after the acute phase of dengue fever has resolved. […] These symptoms may include extreme fatigue, muscle and joint pain, depression, and cognitive impairment. PDS can significantly impact an individual’s quality of life. […] One of the primary symptoms of Post-Dengue Syndrome is persistent fatigue and weakness. […] Even after the acute phase of dengue fever has passed, individuals may continue to experience overwhelming exhaustion. […] Dengue-related arthralgia, characterized by persistent joint and muscle pain, can significantly impact individuals recovering from dengue fever. […] Neurological symptoms are common in individuals experiencing Post-Dengue Syndrome. […] These may include recurrent headaches, cognitive impairment, and mood changes.
  • #77
    https://journals.lww.com/aptm/fulltext/2019/12060/symptoms_of_dengue_at_the_acute_and_post_infection.3.aspx
    The most common symptoms of dengue fever at the acute stage was body ache (81.81%, n=387), followed by headache (71.67%, n=339), loss of appetite (66.80%, n=316), tiredness (53.06 %, n=251) and vomiting (41.86%, n=198). […] The most common symptom during the post-infection stage was body ache (48.62%, n=230), followed by fatigue (39.74%, n=188), and loss of appetite (28.75%, n=136). […] The most common symptoms of dengue fever during acute stage were body ache (myalgia/arthralgia) (81.81%), followed by headache (71.67%), loss of appetite (66.80%), fatigue (53.07%) and vomiting (41.86%). […] The most common symptoms during the post-infection stage were body ache (48.63%), followed by fatigue (39.74%), and loss of appetite (28.75%). […] At least one symptom appeared for 79.70% (n=377) of patients during the post-infection period. […] The study shows a prolonged persistence of clinical symptoms during the postinfection period. […] Persistent clinical symptoms during post-infection period is evident.
  • #78 Understanding the Long-Term Impact of Dengue Fever on Health
    https://www.aksharhospitals.com/blog/long-term-effects-of-dengue-fever
    Post-Dengue Syndrome refers to a cluster of symptoms that persist even after the acute phase of dengue fever has resolved. […] These symptoms may include extreme fatigue, muscle and joint pain, depression, and cognitive impairment. PDS can significantly impact an individual’s quality of life. […] One of the primary symptoms of Post-Dengue Syndrome is persistent fatigue and weakness. […] Even after the acute phase of dengue fever has passed, individuals may continue to experience overwhelming exhaustion. […] Dengue-related arthralgia, characterized by persistent joint and muscle pain, can significantly impact individuals recovering from dengue fever. […] Neurological symptoms are common in individuals experiencing Post-Dengue Syndrome. […] These may include recurrent headaches, cognitive impairment, and mood changes.
  • #79 Burden of Postinfectious Symptoms after Acute Dengue, Vietnam
    https://pmc.ncbi.nlm.nih.gov/articles/PMC9796196/
    We report on postinfectious symptoms in 247 predominantly pediatric patients from Vietnam 3 months after an acute febrile illness; 200 of them had dengue. After acute dengue, we observed a broad spectrum of postviral symptoms ranging from fatigue, joint pain, and muscle pain to vision problems and hair loss. We report 8% patients experienced fatigue, consistent with a study in Singapore reporting 9%, but lower than the 24% in another Singapore study and the 28% reported from Cuba. Our estimate of 47% of persons experiencing 1 symptom is higher than the 8.5% observed in Peru but lower than the 65% experiencing 1 persistent symptom observed in Brazil. […] The alopecia we report in our study has been observed previously, at a much lower rate in 1 study in Brazil and at a similar rate in a recent study from Mexico. Alopecia after dengue has been noted in 1 case report. Vision problems associated with dengue have previously been reported but mainly during the acute phase or soon afterwards. In our study, we saw that these symptoms can persist for several months or start much later after infection, which was also seen in the recent study in Mexico.
  • #80 Dengue Fever in Children: Symptoms, Diagnosis, Treatment, Prevention | Pantai Hospital
    https://www.pantai.com.my/medical-specialties/paediatrics/dengue-fever
    Dengue fever typically causes milder symptoms in younger children and those who are infected for the first time. Moderate to severe symptoms may occur in older children, adults, and those who have previously been infected. […] The following are some typical symptoms of dengue fever: Sudden onset of high fever (40C/104F) […] Fever is the most typical sign of dengue. […] Fever occurs on the 3rd to 14th day after being bitten by an infected mosquito. […] High fever typically lasts for 2 to 7 days. […] High fever can cause convulsion in children below 6 years old. […] Severe headache […] Pain behind the eyes […] Severe pain in the bones, muscle ache, and joint pain […] Bodily rash […] The most tell-tale sign of dengue fever is the rash that often develops and covers most of the body.
  • #81
    https://www.ncid.sg/News-Events/News/Pages/What-are-the-warning-signs-of-severe-dengue-infection.aspx
    The warning signs of severe dengue include bleeding in the gums or nose, blood in urine or stools, heavy menstrual bleeding, severe abdominal pain, persistent vomiting to the point that the patient cannot keep fluids down, lethargy or change in alertness, and breathlessness. […] Other things to watch out for include giddiness when standing or sitting up, decreased urine output, and a poor appetite. […] Dengue patients can suffer dehydration due to poor appetite or vomiting, or diarrhoea in some cases. […] The symptoms of dengue include fever, headache, muscle and joint aches, rashes, vomiting, easy bruising, nausea and mild bleeding from the nose or gums. […] The elderly may have less aches and pains, and may present with just tiredness, sometimes accompanied by a decrease in appetite. This makes it more challenging to diagnose dengue early and to manage it well.
  • #82 Dengue: How to keep children safe | UNICEF South Asia
    https://www.unicef.org/rosa/stories/dengue-how-keep-children-safe
    Not everyone who gets dengue will become seriously unwell and the most serious impacts of dengue can be addressed with swift medical care — so, it’s important to know what dengue symptoms to look out for and when to seek medical attention. […] Most people infected with dengue have no symptoms. But it can cause a feverish illness and in rare cases people can become seriously unwell, need hospital care and even die from dengue. […] If children have symptoms of dengue, they can look similar to other common childhood infections. […] Most people with dengue have mild or no symptoms and will get better in 1–2 weeks. About 1 in 4 people with dengue will develop symptoms. If you do show symptoms, they will usually begin 4–10 days after being bitten by an infected mosquito and last for 2–7 days. Symptoms of dengue may include: A sudden high fever, of up to 40°C, Severe headache, Pain behind the eyes, muscle and joint pains, Nausea, Vomiting, Swollen glands, Skin rash.
  • #83 Dengue Fever in Children: Symptoms, Diagnosis, Treatment, Prevention | Pantai Hospital
    https://www.pantai.com.my/medical-specialties/paediatrics/dengue-fever
    Dengue fever typically causes milder symptoms in younger children and those who are infected for the first time. Moderate to severe symptoms may occur in older children, adults, and those who have previously been infected. […] The following are some typical symptoms of dengue fever: Sudden onset of high fever (40C/104F) […] Fever is the most typical sign of dengue. […] Fever occurs on the 3rd to 14th day after being bitten by an infected mosquito. […] High fever typically lasts for 2 to 7 days. […] High fever can cause convulsion in children below 6 years old. […] Severe headache […] Pain behind the eyes […] Severe pain in the bones, muscle ache, and joint pain […] Bodily rash […] The most tell-tale sign of dengue fever is the rash that often develops and covers most of the body.
  • #84 Dengue: How to keep children safe | UNICEF South Asia
    https://www.unicef.org/rosa/stories/dengue-how-keep-children-safe
    Children and infants with dengue may also become more irritable than usual and their appetite and sleep patterns may change. […] Symptoms of dengue can become severe within a few hours. If you, or your child, develops any symptoms of severe dengue, seek urgent medical attention immediately. […] Severe dengue symptoms often come after fever has gone away and include: Severe abdominal pain, Persistent vomiting, Rapid breathing, Bleeding gums or nose, Fatigue, Restlessness, Blood in vomit or stool, Being very thirsty, Pale and cold skin, Feeling weak, Sleepiness, lack of energy, or irritability. […] If your child, or anyone with suspected dengue develops any of these symptoms, it is important to seek urgent medical attention. […] Young children and particularly infants are at a higher risk of developing severe dengue illness and complications than healthy adults. This is because their immune systems are weaker. […] With quick medical attention the worst impacts of severe dengue in children can be avoided.
  • #85 Dengue: How to keep children safe | UNICEF South Asia
    https://www.unicef.org/rosa/stories/dengue-how-keep-children-safe
    Children and infants with dengue may also become more irritable than usual and their appetite and sleep patterns may change. […] Symptoms of dengue can become severe within a few hours. If you, or your child, develops any symptoms of severe dengue, seek urgent medical attention immediately. […] Severe dengue symptoms often come after fever has gone away and include: Severe abdominal pain, Persistent vomiting, Rapid breathing, Bleeding gums or nose, Fatigue, Restlessness, Blood in vomit or stool, Being very thirsty, Pale and cold skin, Feeling weak, Sleepiness, lack of energy, or irritability. […] If your child, or anyone with suspected dengue develops any of these symptoms, it is important to seek urgent medical attention. […] Young children and particularly infants are at a higher risk of developing severe dengue illness and complications than healthy adults. This is because their immune systems are weaker. […] With quick medical attention the worst impacts of severe dengue in children can be avoided.
  • #86 Dengue Fever in Children: Symptoms, Diagnosis, Treatment, Prevention | Pantai Hospital
    https://www.pantai.com.my/medical-specialties/paediatrics/dengue-fever
    Dengue fever typically causes milder symptoms in younger children and those who are infected for the first time. Moderate to severe symptoms may occur in older children, adults, and those who have previously been infected. […] The following are some typical symptoms of dengue fever: Sudden onset of high fever (40C/104F) […] Fever is the most typical sign of dengue. […] Fever occurs on the 3rd to 14th day after being bitten by an infected mosquito. […] High fever typically lasts for 2 to 7 days. […] High fever can cause convulsion in children below 6 years old. […] Severe headache […] Pain behind the eyes […] Severe pain in the bones, muscle ache, and joint pain […] Bodily rash […] The most tell-tale sign of dengue fever is the rash that often develops and covers most of the body.
  • #87 Dengue Clinical Presentation: History, Physical Examination
    https://emedicine.medscape.com/article/215840-clinical
    Recovery is complete but slow, with fatigue and exhaustion often persisting after the fever has subsided. The convalescent phase may last for 2 weeks. […] Patients are at risk for development of dengue hemorrhagic fever or dengue shock syndrome at approximately the time of defervescence. Abdominal pain in conjunction with restlessness, change in mental status, hypothermia, and a drop in the platelet count presages the development of dengue hemorrhagic fever. […] Of patients with dengue hemorrhagic fever, 90% are younger than 15 years. The initial phase of dengue hemorrhagic fever is similar to that of dengue fever and other febrile viral illnesses. Shortly after the fever breaks (or sometimes within 24 hours before), signs of plasma leakage appear, along with the development of hemorrhagic symptoms such as bleeding from sites of trauma, gastrointestinal bleeding, and hematuria. Patients may also present with abdominal pain, vomiting, febrile seizures (in children), and a decreased level of consciousness. […] If left untreated, dengue hemorrhagic fever most likely progresses to dengue shock syndrome. Common symptoms in impending shock include abdominal pain, vomiting, and restlessness. Patients also may have symptoms related to circulatory failure.
  • #88 Dengue: How to keep children safe | UNICEF South Asia
    https://www.unicef.org/rosa/stories/dengue-how-keep-children-safe
    Children and infants with dengue may also become more irritable than usual and their appetite and sleep patterns may change. […] Symptoms of dengue can become severe within a few hours. If you, or your child, develops any symptoms of severe dengue, seek urgent medical attention immediately. […] Severe dengue symptoms often come after fever has gone away and include: Severe abdominal pain, Persistent vomiting, Rapid breathing, Bleeding gums or nose, Fatigue, Restlessness, Blood in vomit or stool, Being very thirsty, Pale and cold skin, Feeling weak, Sleepiness, lack of energy, or irritability. […] If your child, or anyone with suspected dengue develops any of these symptoms, it is important to seek urgent medical attention. […] Young children and particularly infants are at a higher risk of developing severe dengue illness and complications than healthy adults. This is because their immune systems are weaker. […] With quick medical attention the worst impacts of severe dengue in children can be avoided.
  • #89
    https://www.ncid.sg/News-Events/News/Pages/What-are-the-warning-signs-of-severe-dengue-infection.aspx
    The warning signs of severe dengue include bleeding in the gums or nose, blood in urine or stools, heavy menstrual bleeding, severe abdominal pain, persistent vomiting to the point that the patient cannot keep fluids down, lethargy or change in alertness, and breathlessness. […] Other things to watch out for include giddiness when standing or sitting up, decreased urine output, and a poor appetite. […] Dengue patients can suffer dehydration due to poor appetite or vomiting, or diarrhoea in some cases. […] The symptoms of dengue include fever, headache, muscle and joint aches, rashes, vomiting, easy bruising, nausea and mild bleeding from the nose or gums. […] The elderly may have less aches and pains, and may present with just tiredness, sometimes accompanied by a decrease in appetite. This makes it more challenging to diagnose dengue early and to manage it well.
  • #90
    https://www.ncid.sg/News-Events/News/Pages/What-are-the-warning-signs-of-severe-dengue-infection.aspx
    The warning signs of severe dengue include bleeding in the gums or nose, blood in urine or stools, heavy menstrual bleeding, severe abdominal pain, persistent vomiting to the point that the patient cannot keep fluids down, lethargy or change in alertness, and breathlessness. […] Other things to watch out for include giddiness when standing or sitting up, decreased urine output, and a poor appetite. […] Dengue patients can suffer dehydration due to poor appetite or vomiting, or diarrhoea in some cases. […] The symptoms of dengue include fever, headache, muscle and joint aches, rashes, vomiting, easy bruising, nausea and mild bleeding from the nose or gums. […] The elderly may have less aches and pains, and may present with just tiredness, sometimes accompanied by a decrease in appetite. This makes it more challenging to diagnose dengue early and to manage it well.
  • #91
    https://www.ncid.sg/News-Events/News/Pages/What-are-the-warning-signs-of-severe-dengue-infection.aspx
    The warning signs of severe dengue include bleeding in the gums or nose, blood in urine or stools, heavy menstrual bleeding, severe abdominal pain, persistent vomiting to the point that the patient cannot keep fluids down, lethargy or change in alertness, and breathlessness. […] Other things to watch out for include giddiness when standing or sitting up, decreased urine output, and a poor appetite. […] Dengue patients can suffer dehydration due to poor appetite or vomiting, or diarrhoea in some cases. […] The symptoms of dengue include fever, headache, muscle and joint aches, rashes, vomiting, easy bruising, nausea and mild bleeding from the nose or gums. […] The elderly may have less aches and pains, and may present with just tiredness, sometimes accompanied by a decrease in appetite. This makes it more challenging to diagnose dengue early and to manage it well.
  • #92 It’s Not ‘Just Dengue’ When It Lasts For Months – CodeBlue
    https://vgh.pth.mybluehost.me/2024/09/its-not-just-dengue-when-it-lasts-for-months/
    Post dengue syndrome can severely affect a persons quality of life, and the experience can cause a person to get depressed, especially those who had expected that their experience with dengue would be mild. […] Simply put, Dr Shanthi draws similarities between PDS and a tsunami even though the attack has come and gone, the damage has been done, leaving behind chronic inflammation and an immune system that has become highly activated. […] Overall, Dr Shanthi said that elderly patients and those with comorbid conditions like hypertension, ischemic heart disease, obesity and autoimmune disease are more likely to experience severe dengue, which increases the likelihood of experiencing post-dengue syndrome. […] Among these, the elderly are also more likely to require high-dependency or intensive care as their health can deteriorate more quickly, with symptoms that linger for a longer period.
  • #93 It’s Not ‘Just Dengue’ When It Lasts For Months – CodeBlue
    https://vgh.pth.mybluehost.me/2024/09/its-not-just-dengue-when-it-lasts-for-months/
    Post dengue syndrome can severely affect a persons quality of life, and the experience can cause a person to get depressed, especially those who had expected that their experience with dengue would be mild. […] Simply put, Dr Shanthi draws similarities between PDS and a tsunami even though the attack has come and gone, the damage has been done, leaving behind chronic inflammation and an immune system that has become highly activated. […] Overall, Dr Shanthi said that elderly patients and those with comorbid conditions like hypertension, ischemic heart disease, obesity and autoimmune disease are more likely to experience severe dengue, which increases the likelihood of experiencing post-dengue syndrome. […] Among these, the elderly are also more likely to require high-dependency or intensive care as their health can deteriorate more quickly, with symptoms that linger for a longer period.
  • #94
    https://www.ncid.sg/News-Events/News/Pages/What-are-the-warning-signs-of-severe-dengue-infection.aspx
    The warning signs of severe dengue include bleeding in the gums or nose, blood in urine or stools, heavy menstrual bleeding, severe abdominal pain, persistent vomiting to the point that the patient cannot keep fluids down, lethargy or change in alertness, and breathlessness. […] Other things to watch out for include giddiness when standing or sitting up, decreased urine output, and a poor appetite. […] Dengue patients can suffer dehydration due to poor appetite or vomiting, or diarrhoea in some cases. […] The symptoms of dengue include fever, headache, muscle and joint aches, rashes, vomiting, easy bruising, nausea and mild bleeding from the nose or gums. […] The elderly may have less aches and pains, and may present with just tiredness, sometimes accompanied by a decrease in appetite. This makes it more challenging to diagnose dengue early and to manage it well.
  • #95 Dengue fever – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/dengue-fever/diagnosis-treatment/drc-20353084
    Diagnosing dengue fever can be difficult because its signs and symptoms can be easily confused with those of other diseases such as chikungunya, Zika virus, malaria and typhoid fever. […] While recovering from dengue fever, drink plenty of fluids. Call your doctor right away if you have any of the following signs and symptoms of dehydration: Decreased urination, Few or no tears, Dry mouth or lips, Lethargy or confusion, Cold or clammy extremities. […] If you have severe dengue fever, you may need: Supportive care in a hospital, Intravenous (IV) fluid and electrolyte replacement, Blood pressure monitoring, Transfusion to replace blood loss. […] For dengue fever, some basic questions to ask your doctor include: What’s the most likely cause of my symptoms? What kinds of tests do I need? What treatments are available? How long will it be before I’m feeling better? Are there any long-term effects of this illness? […] Be prepared to answer questions from your doctor, such as: When did your symptoms begin? Have your symptoms been continuous or occasional? How severe are your symptoms? Does anything seem to make your symptoms better or worse?
  • #96 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #97 How Soon after Exposure Do Symptoms of Dengue Appear
    https://www.parashospitals.com/blogs/soon-exposure-symptoms-dengue-appear
    During the first week of illness, the diagnosis of dengue virus infection may be established via detection of viral nucleic acid in serum by means of reverse-transcriptase polymerase chain reaction (RT-PCR) assay (typically positive during the first five days of illness) or via detection of viral antigen nonstructural protein 1 (NS1; typically positive during the first seven days of illness). […] In primary infection, the sensitivity of NS1 detection can exceed 90 percent, and antigenemia may persist for several days after resolution of fever; in secondary infection, the sensitivity of NS1 detection is lower (60 to 80 percent).
  • #98 How Soon after Exposure Do Symptoms of Dengue Appear
    https://www.parashospitals.com/blogs/soon-exposure-symptoms-dengue-appear
    During the first week of illness, the diagnosis of dengue virus infection may be established via detection of viral nucleic acid in serum by means of reverse-transcriptase polymerase chain reaction (RT-PCR) assay (typically positive during the first five days of illness) or via detection of viral antigen nonstructural protein 1 (NS1; typically positive during the first seven days of illness). […] In primary infection, the sensitivity of NS1 detection can exceed 90 percent, and antigenemia may persist for several days after resolution of fever; in secondary infection, the sensitivity of NS1 detection is lower (60 to 80 percent).
  • #99 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #100 How Soon after Exposure Do Symptoms of Dengue Appear
    https://www.parashospitals.com/blogs/soon-exposure-symptoms-dengue-appear
    During the first week of illness, the diagnosis of dengue virus infection may be established via detection of viral nucleic acid in serum by means of reverse-transcriptase polymerase chain reaction (RT-PCR) assay (typically positive during the first five days of illness) or via detection of viral antigen nonstructural protein 1 (NS1; typically positive during the first seven days of illness). […] In primary infection, the sensitivity of NS1 detection can exceed 90 percent, and antigenemia may persist for several days after resolution of fever; in secondary infection, the sensitivity of NS1 detection is lower (60 to 80 percent).
  • #101 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #102 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #103 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #104 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Most patients clinically improve during this phase, but those with substantial plasma leakage can, within a few hours, develop severe dengue. […] Patients with severe plasma leakage may have pleural effusions, ascites, hypoproteinemia, or hemoconcentration. […] Patients may appear to be well despite early signs of shock. However, once hypotension develops, systolic blood pressure rapidly declines, and irreversible shock and death may ensue despite resuscitation. […] Severe dengue is defined by dengue with any of the following clinical manifestations: severe plasma leakage leading to shock or fluid accumulation with respiratory distress; severe bleeding; or severe organ impairment such as hepatitis (elevated transaminases 1,000 IU/L), impaired consciousness, or heart impairment.
  • #105 Dengue: Practice Essentials, Background, Pathophysiology
    https://emedicine.medscape.com/article/215840-overview
    Many patients with dengue experience a prodrome of chills; rash, including erythematous mottling of the skin; and facial flushing, which may last 2-3 days. […] Dengue should be suspected in individuals who present with high fever (104F/40C), retro-orbital headache, muscle and joint pain, nausea, lymphadenopathy, vomiting, and rash and who have traveled within 2 weeks of symptom onset to an area where appropriate vectors are present and dengue transmission may be occurring. […] Severe dengue is characterized by severe plasma leakage leading to shock, which is defined by symptoms such as tachycardia, a narrowing of the pulse pressure (a difference in systolic and diastolic pressure less than 20 mmHg), delayed capillary filling, and hypotension. […] The initial phase of severe dengue resembles that of dengue fever and other febrile viral illnesses. Signs of plasma leakage typically appear shortly after the fever breaks, which occurs 3-7 days after symptom onset or sometimes within 24 hours before.
  • #106 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Dengue fever symptoms start to appear four to 10 days after a mosquito bite and can last three to seven days. About 1 in 20 people sick with dengue will develop severe dengue after their initial symptoms begin to fade. […] Severe dengue is a life-threatening worsening of dengue symptoms. Warning signs of severe dengue are usually seen 24 to 48 hours after your fever goes away. […] Severe dengue is a medical emergency that can be fatal. If you have dengue or live in an area where dengue is common, go to the nearest ER immediately if you experience any of these symptoms: Stomach/abdominal pain. Frequent vomiting. Throwing up blood or blood in your poop (stool). Nose bleeds or bleeding gums. Extreme tiredness, restlessness or irritability. […] Initial symptoms of dengue last three to seven days. Most people begin to feel better after this, but some have life-threatening severe dengue that requires treatment in a medical facility.
  • #107 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The disease is classified as either dengue or severe dengue. […] Severe dengue is characterized by dengue fever accompanied by severe plasma leakage, hemorrhage, impaired consciousness, myocardial dysfunction, pulmonary dysfunction, and organ dysfunction, including transaminitis greater than 1000 IU/L. […] The treatment approach for dengue fever varies depending on the patient’s illness phase. Patients without warning signs can typically be treated as outpatients with acetaminophen and sufficient oral fluids. […] Patients presenting with warning signs of the disease, severe dengue fever, or having risk factors such as age, pregnancy status, diabetes mellitus, or those who are living alone should be evaluated for hospitalization.
  • #108
    https://www.health.nsw.gov.au/Infectious/factsheets/Pages/dengue.aspx
    If you have these symptoms, speak to your doctor or go to the emergency department immediately. […] There is no specific treatment for dengue fever. Patients should seek medical advice, rest and drink plenty of fluids. Paracetamol can be taken to bring down fever and reduce joint pains. However, aspirin or ibuprofen should not be taken since they can increase the risk of bleeding. […] For severe dengue, emergency medical care is required for close monitoring and treatment in hospital.
  • #109 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The disease is classified as either dengue or severe dengue. […] Severe dengue is characterized by dengue fever accompanied by severe plasma leakage, hemorrhage, impaired consciousness, myocardial dysfunction, pulmonary dysfunction, and organ dysfunction, including transaminitis greater than 1000 IU/L. […] The treatment approach for dengue fever varies depending on the patient’s illness phase. Patients without warning signs can typically be treated as outpatients with acetaminophen and sufficient oral fluids. […] Patients presenting with warning signs of the disease, severe dengue fever, or having risk factors such as age, pregnancy status, diabetes mellitus, or those who are living alone should be evaluated for hospitalization.
  • #110
    https://www.health.nsw.gov.au/Infectious/factsheets/Pages/dengue.aspx
    If you have these symptoms, speak to your doctor or go to the emergency department immediately. […] There is no specific treatment for dengue fever. Patients should seek medical advice, rest and drink plenty of fluids. Paracetamol can be taken to bring down fever and reduce joint pains. However, aspirin or ibuprofen should not be taken since they can increase the risk of bleeding. […] For severe dengue, emergency medical care is required for close monitoring and treatment in hospital.
  • #111 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #112 Dengue fever – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/dengue-fever/diagnosis-treatment/drc-20353084
    Diagnosing dengue fever can be difficult because its signs and symptoms can be easily confused with those of other diseases such as chikungunya, Zika virus, malaria and typhoid fever. […] While recovering from dengue fever, drink plenty of fluids. Call your doctor right away if you have any of the following signs and symptoms of dehydration: Decreased urination, Few or no tears, Dry mouth or lips, Lethargy or confusion, Cold or clammy extremities. […] If you have severe dengue fever, you may need: Supportive care in a hospital, Intravenous (IV) fluid and electrolyte replacement, Blood pressure monitoring, Transfusion to replace blood loss. […] For dengue fever, some basic questions to ask your doctor include: What’s the most likely cause of my symptoms? What kinds of tests do I need? What treatments are available? How long will it be before I’m feeling better? Are there any long-term effects of this illness? […] Be prepared to answer questions from your doctor, such as: When did your symptoms begin? Have your symptoms been continuous or occasional? How severe are your symptoms? Does anything seem to make your symptoms better or worse?
  • #113 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #114
    https://www.health.nsw.gov.au/Infectious/factsheets/Pages/dengue.aspx
    If you have these symptoms, speak to your doctor or go to the emergency department immediately. […] There is no specific treatment for dengue fever. Patients should seek medical advice, rest and drink plenty of fluids. Paracetamol can be taken to bring down fever and reduce joint pains. However, aspirin or ibuprofen should not be taken since they can increase the risk of bleeding. […] For severe dengue, emergency medical care is required for close monitoring and treatment in hospital.
  • #115 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #116 Dengue fever – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/dengue-fever/diagnosis-treatment/drc-20353084
    Diagnosing dengue fever can be difficult because its signs and symptoms can be easily confused with those of other diseases such as chikungunya, Zika virus, malaria and typhoid fever. […] While recovering from dengue fever, drink plenty of fluids. Call your doctor right away if you have any of the following signs and symptoms of dehydration: Decreased urination, Few or no tears, Dry mouth or lips, Lethargy or confusion, Cold or clammy extremities. […] If you have severe dengue fever, you may need: Supportive care in a hospital, Intravenous (IV) fluid and electrolyte replacement, Blood pressure monitoring, Transfusion to replace blood loss. […] For dengue fever, some basic questions to ask your doctor include: What’s the most likely cause of my symptoms? What kinds of tests do I need? What treatments are available? How long will it be before I’m feeling better? Are there any long-term effects of this illness? […] Be prepared to answer questions from your doctor, such as: When did your symptoms begin? Have your symptoms been continuous or occasional? How severe are your symptoms? Does anything seem to make your symptoms better or worse?
  • #117 Dengue fever – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/dengue-fever/diagnosis-treatment/drc-20353084
    Diagnosing dengue fever can be difficult because its signs and symptoms can be easily confused with those of other diseases such as chikungunya, Zika virus, malaria and typhoid fever. […] While recovering from dengue fever, drink plenty of fluids. Call your doctor right away if you have any of the following signs and symptoms of dehydration: Decreased urination, Few or no tears, Dry mouth or lips, Lethargy or confusion, Cold or clammy extremities. […] If you have severe dengue fever, you may need: Supportive care in a hospital, Intravenous (IV) fluid and electrolyte replacement, Blood pressure monitoring, Transfusion to replace blood loss. […] For dengue fever, some basic questions to ask your doctor include: What’s the most likely cause of my symptoms? What kinds of tests do I need? What treatments are available? How long will it be before I’m feeling better? Are there any long-term effects of this illness? […] Be prepared to answer questions from your doctor, such as: When did your symptoms begin? Have your symptoms been continuous or occasional? How severe are your symptoms? Does anything seem to make your symptoms better or worse?
  • #118 Dengue fever – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/dengue-fever/diagnosis-treatment/drc-20353084
    Diagnosing dengue fever can be difficult because its signs and symptoms can be easily confused with those of other diseases such as chikungunya, Zika virus, malaria and typhoid fever. […] While recovering from dengue fever, drink plenty of fluids. Call your doctor right away if you have any of the following signs and symptoms of dehydration: Decreased urination, Few or no tears, Dry mouth or lips, Lethargy or confusion, Cold or clammy extremities. […] If you have severe dengue fever, you may need: Supportive care in a hospital, Intravenous (IV) fluid and electrolyte replacement, Blood pressure monitoring, Transfusion to replace blood loss. […] For dengue fever, some basic questions to ask your doctor include: What’s the most likely cause of my symptoms? What kinds of tests do I need? What treatments are available? How long will it be before I’m feeling better? Are there any long-term effects of this illness? […] Be prepared to answer questions from your doctor, such as: When did your symptoms begin? Have your symptoms been continuous or occasional? How severe are your symptoms? Does anything seem to make your symptoms better or worse?
  • #119 Dengue fever – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/dengue-fever/diagnosis-treatment/drc-20353084
    Diagnosing dengue fever can be difficult because its signs and symptoms can be easily confused with those of other diseases such as chikungunya, Zika virus, malaria and typhoid fever. […] While recovering from dengue fever, drink plenty of fluids. Call your doctor right away if you have any of the following signs and symptoms of dehydration: Decreased urination, Few or no tears, Dry mouth or lips, Lethargy or confusion, Cold or clammy extremities. […] If you have severe dengue fever, you may need: Supportive care in a hospital, Intravenous (IV) fluid and electrolyte replacement, Blood pressure monitoring, Transfusion to replace blood loss. […] For dengue fever, some basic questions to ask your doctor include: What’s the most likely cause of my symptoms? What kinds of tests do I need? What treatments are available? How long will it be before I’m feeling better? Are there any long-term effects of this illness? […] Be prepared to answer questions from your doctor, such as: When did your symptoms begin? Have your symptoms been continuous or occasional? How severe are your symptoms? Does anything seem to make your symptoms better or worse?
  • #120 Dengue fever – UF Health
    https://ufhealth.org/conditions-and-treatments/dengue-fever
    Dengue fever is a virus-caused disease that is spread by mosquitoes. Dengue in its mild form causes fever and a rash and lasts about a week. Severe dengue can cause shock, internal bleeding, and death. About 1 out of 20 people with dengue will develop severe dengue within a few hours after symptoms start. The main risk factor for severe dengue is a prior infection with dengue. […] Dengue fever begins with a sudden high fever, often as high as 105F (40.5C), 4 to 7 days after the infection. […] Symptoms of severe dengue can occur 24 to 48 hours after fever has gone away. Severe symptoms include: Severe stomach pain and tenderness, Vomiting often (at least 3 times in 24 hours), Bleeding from the nose or gums, Vomiting blood or passing blood in the stools or urine, Bleeding under the skin (looks like bruises), Difficulty breathing, rapid breathing, Feeling tired, restless, or irritable.
  • #121 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Most patients clinically improve during this phase, but those with substantial plasma leakage can, within a few hours, develop severe dengue. […] Patients with severe plasma leakage may have pleural effusions, ascites, hypoproteinemia, or hemoconcentration. […] Patients may appear to be well despite early signs of shock. However, once hypotension develops, systolic blood pressure rapidly declines, and irreversible shock and death may ensue despite resuscitation. […] Severe dengue is defined by dengue with any of the following clinical manifestations: severe plasma leakage leading to shock or fluid accumulation with respiratory distress; severe bleeding; or severe organ impairment such as hepatitis (elevated transaminases 1,000 IU/L), impaired consciousness, or heart impairment.
  • #122 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Dengue begins abruptly after a typical incubation period of 57 days, and the course follows 3 phases: febrile, critical, and recovery. […] Early clinical findings are nonspecific. Dengue requires a high index of suspicion because recognizing early signs of shock and promptly initiating intensive supportive therapy with intravenous fluids can reduce risk of death among patients with severe dengue to 0.5%. […] Warning signs of progression to severe dengue usually occur in the late febrile phase around the time of defervescence, and include persistent vomiting, severe abdominal pain, fluid accumulation, mucosal bleeding, lethargy/restlessness, postural hypotension, liver enlargement, and progressive increase in hematocrit (i.e., hemoconcentration). […] The critical phase of dengue begins at defervescence and typically lasts 2448 hours.
  • #123 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Most people recover from dengue fever without any lasting complications. If you have symptoms of dengue fever, you have about a 1 in 20 chance of it worsening to severe dengue. If you have severe dengue and are treated immediately at a hospital or medical facility, you have a greater than 99% chance of recovering. […] Yes. Because there are at least four versions (strains) of the dengue virus, you can get dengue more than once. You’ll usually become immune to the first strain you get sick with and cant get it again. But you can get sick with one of the other three strains after that. In fact, you’re more likely to get severely sick if you get dengue more than once.
  • #124 Dengue fever – UF Health
    https://ufhealth.org/conditions-and-treatments/dengue-fever
    Mild cases of dengue generally last a week or more. Although uncomfortable, mild dengue fever is not deadly. People with the condition should fully recover. In some Latin American and Asian countries, severe dengue is a leading cause of death and severe illness. Early detection and treatment of severe dengue can greatly reduce the risk of death.
  • #125 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Most people recover from dengue fever without any lasting complications. If you have symptoms of dengue fever, you have about a 1 in 20 chance of it worsening to severe dengue. If you have severe dengue and are treated immediately at a hospital or medical facility, you have a greater than 99% chance of recovering. […] Yes. Because there are at least four versions (strains) of the dengue virus, you can get dengue more than once. You’ll usually become immune to the first strain you get sick with and cant get it again. But you can get sick with one of the other three strains after that. In fact, you’re more likely to get severely sick if you get dengue more than once.
  • #126 Dengue: Practice Essentials, Background, Pathophysiology
    https://emedicine.medscape.com/article/215840-overview
    Dengue fever typically presents with a sudden onset of high fever, headache, muscle and joint pain, and generalized lymphadenopathy. A rash may develop alongside recurrent fever following an afebrile period, and respiratory symptoms such as cough, sore throat, and rhinorrhea also can occur. […] In more severe cases, dengue can lead to dengue hemorrhagic fever, characterized by a bleeding tendency and shock, which can be fatal. […] Dengue fever typically is a self-limited disease with a mortality rate of less than 1% when detected early and with access to proper medical care. When treated, severe dengue has a mortality rate of 2-5%, but, when left untreated, the mortality rate is as high as 20%. […] On average, dengue becomes symptomatic after a 4- to 10-day incubation period (range, 3-14 days). Dengue symptoms usually last 2-7 days.
  • #127
    https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue
    Most people who get dengue will not have symptoms. But for those who do, the most common symptoms are high fever, headache, body aches, nausea, and rash. Most will get better in 12 weeks. Some people develop severe dengue and need care in a hospital. […] In severe cases, dengue can be fatal. […] Most people with dengue have mild or no symptoms and will get better in 12 weeks. Rarely, dengue can be severe and lead to death. […] If symptoms occur, they usually begin 4-10 days after infection and last for 2-7 days. Symptoms may include: high fever (40C/104F), severe headache, pain behind the eyes, muscle and joint pains, nausea, vomiting, swollen glands, rash. […] Individuals who are infected for the second time are at greater risk of severe dengue. […] Severe dengue symptoms often come after the fever has gone away: severe abdominal pain, persistent vomiting, rapid breathing, bleeding gums or nose, fatigue, restlessness, blood in vomit or stool, being very thirsty, pale and cold skin, feeling weak. […] People with these severe symptoms should get care right away. […] After recovery, people who have had dengue may feel tired for several weeks.
  • #128 Dengue: Practice Essentials, Background, Pathophysiology
    https://emedicine.medscape.com/article/215840-overview
    Dengue fever typically presents with a sudden onset of high fever, headache, muscle and joint pain, and generalized lymphadenopathy. A rash may develop alongside recurrent fever following an afebrile period, and respiratory symptoms such as cough, sore throat, and rhinorrhea also can occur. […] In more severe cases, dengue can lead to dengue hemorrhagic fever, characterized by a bleeding tendency and shock, which can be fatal. […] Dengue fever typically is a self-limited disease with a mortality rate of less than 1% when detected early and with access to proper medical care. When treated, severe dengue has a mortality rate of 2-5%, but, when left untreated, the mortality rate is as high as 20%. […] On average, dengue becomes symptomatic after a 4- to 10-day incubation period (range, 3-14 days). Dengue symptoms usually last 2-7 days.
  • #129
    https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue
    Most people who get dengue will not have symptoms. But for those who do, the most common symptoms are high fever, headache, body aches, nausea, and rash. Most will get better in 12 weeks. Some people develop severe dengue and need care in a hospital. […] In severe cases, dengue can be fatal. […] Most people with dengue have mild or no symptoms and will get better in 12 weeks. Rarely, dengue can be severe and lead to death. […] If symptoms occur, they usually begin 4-10 days after infection and last for 2-7 days. Symptoms may include: high fever (40C/104F), severe headache, pain behind the eyes, muscle and joint pains, nausea, vomiting, swollen glands, rash. […] Individuals who are infected for the second time are at greater risk of severe dengue. […] Severe dengue symptoms often come after the fever has gone away: severe abdominal pain, persistent vomiting, rapid breathing, bleeding gums or nose, fatigue, restlessness, blood in vomit or stool, being very thirsty, pale and cold skin, feeling weak. […] People with these severe symptoms should get care right away. […] After recovery, people who have had dengue may feel tired for several weeks.
  • #130 Dengue: Practice Essentials, Background, Pathophysiology
    https://emedicine.medscape.com/article/215840-overview
    Dengue fever typically presents with a sudden onset of high fever, headache, muscle and joint pain, and generalized lymphadenopathy. A rash may develop alongside recurrent fever following an afebrile period, and respiratory symptoms such as cough, sore throat, and rhinorrhea also can occur. […] In more severe cases, dengue can lead to dengue hemorrhagic fever, characterized by a bleeding tendency and shock, which can be fatal. […] Dengue fever typically is a self-limited disease with a mortality rate of less than 1% when detected early and with access to proper medical care. When treated, severe dengue has a mortality rate of 2-5%, but, when left untreated, the mortality rate is as high as 20%. […] On average, dengue becomes symptomatic after a 4- to 10-day incubation period (range, 3-14 days). Dengue symptoms usually last 2-7 days.
  • #131 Dengue Fever: Symptoms, Causes, Treatment and Vaccine | Ada
    https://ada.com/conditions/dengue-fever/
    The critical stage of dengue fever begins when the initial fever breaks and lasts between 24 and 48 hours. It is known as the critical phase because, although most affected people improve, some people begin to show severe symptoms. This is also known as dengue hemorrhagic fever. Dengue hemorrhagic fever is most common in children who are younger than 15 years of age and people who have had the infection previously. […] Symptoms of dengue hemorrhagic fever include: Severe belly pain, Bleeding from any part of the body, most commonly the gums, A very high fever, Persistent vomiting or vomiting blood, Rapid breathing or difficulty breathing, A skin rash that is red and blotchy and may result in peeling skin, Listlessness and fatigue. […] If the symptoms of dengue hemorrhagic fever are not well managed, they may lead to severe bleeding and, consequently, shock. This may develop into dengue shock syndrome. This condition can cause death if not promptly and adequately treated. […] Generally, dengue fever is a self-limiting infection that naturally passes within two weeks of infection. People who develop dengue hemorrhagic fever have a higher risk of life-threatening complications.
  • #132 Dengue Fever: Symptoms, Vaccine, Causes, Contagious, Treatment & Death Rate
    https://www.medicinenet.com/dengue_fever/article.htm
    A characteristic itchy rash (small red spots, called petechiae) appears along with the fever and spreads from the extremities to cover the entire body except for the face. […] The acute phase of dengue with fever and muscle pain (myalgia) lasts about one to two weeks. […] The prognosis for dengue is usually good. The worst symptoms of the illness typically last 1 to 2 weeks, and most patients will fully recover within several additional weeks. […] Typical dengue infection is fatal in less than 1% of cases; however, the more severe dengue hemorrhagic fever is fatal in 2.5% of cases. If dengue hemorrhagic fever is not treated, mortality (death) rates can be as high as 20%-50%. […] Dengue hemorrhagic fever is a more severe form of viral illness. Symptoms include headache, fever, rash, and evidence of bleeding (hemorrhage) in the body. […] In DHF, there is bleeding with easy bruising, red or purple blood spots in the skin (petechiae), spitting up blood (hematemesis), blood in the stool (melena), bleeding gums, and nosebleeds (epistaxis).
  • #133 Dengue: Practice Essentials, Background, Pathophysiology
    https://emedicine.medscape.com/article/215840-overview
    Dengue fever typically presents with a sudden onset of high fever, headache, muscle and joint pain, and generalized lymphadenopathy. A rash may develop alongside recurrent fever following an afebrile period, and respiratory symptoms such as cough, sore throat, and rhinorrhea also can occur. […] In more severe cases, dengue can lead to dengue hemorrhagic fever, characterized by a bleeding tendency and shock, which can be fatal. […] Dengue fever typically is a self-limited disease with a mortality rate of less than 1% when detected early and with access to proper medical care. When treated, severe dengue has a mortality rate of 2-5%, but, when left untreated, the mortality rate is as high as 20%. […] On average, dengue becomes symptomatic after a 4- to 10-day incubation period (range, 3-14 days). Dengue symptoms usually last 2-7 days.
  • #134
    https://www.healthxchange.sg/children/health-scares-outbreaks/dengue-fever-severe-dengue
    Patients who develop warning signs (in particular lethargy and persistent vomiting) and those with a low platelet count and high hematocrit (elevated red blood cell count) are at very high risk of developing very severe dengue, organ failure or even death. […] There is no known cure for severe dengue. […] With prompt treatment and care, a patient can recover even from severe dengue. However, if treatment is delayed and the patient develops shock or multi-organ failure, the fatality rate rises.
  • #135 Dengue Fever Recovery Phase – Dengue Recovery Symptoms
    https://www.medkart.in/blog/dengue-fever-recovery-phase
    The dengue recovery time varies depending on the severity of the illness and the individuals immune response. In most cases, individuals with mild dengue fever begin to recover within a week after the onset of symptoms. However, the recovery process may take longer for those who experience more severe symptoms or complications.
  • #136 Dengue Fever: Timeline for Recovery and Treatment | Passport Health
    https://www.passporthealthusa.com/2024/12/dengue-fever-timeline-for-recovery-and-treatment/
    Once it’s been determined that you are infected with a dengue virus, it’s important to seek medical help so that a healthcare provider can assist you and help appropriately treat your symptoms. With treating the mild symptoms until the infection is gone you should start to feel better after about a week. […] But, it could take a few weeks for your body to feel normal again and for all of the symptoms to clear. As with any virus, seek medical help if your symptoms do not improve.
  • #137 Dengue Fever: Timeline for Recovery and Treatment | Passport Health
    https://www.passporthealthusa.com/2024/12/dengue-fever-timeline-for-recovery-and-treatment/
    Once it’s been determined that you are infected with a dengue virus, it’s important to seek medical help so that a healthcare provider can assist you and help appropriately treat your symptoms. With treating the mild symptoms until the infection is gone you should start to feel better after about a week. […] But, it could take a few weeks for your body to feel normal again and for all of the symptoms to clear. As with any virus, seek medical help if your symptoms do not improve.
  • #138 It’s Not ‘Just Dengue’ When It Lasts For Months – CodeBlue
    https://vgh.pth.mybluehost.me/2024/09/its-not-just-dengue-when-it-lasts-for-months/
    Severe dengue can take a heavy toll on your health, and some suffer even more with post-dengue syndrome that can linger for months or more. […] However, our nationwide cumulative dengue cases stood at 83,131 as of July 20, 2024. […] the consequences can be dire as patients with severe dengue often require hospitalisation and face higher likelihood of internal bleeding, plasma leakage, organ damage, respiratory problems and even death. […] This recognised but lesser-known phenomenon is known as post-dengue syndrome. […] Bahwanees experience is known as post-dengue syndrome, which is the clinical manifestation of dengue fever that persists for more than six weeks after the acute phase is over, explained Dr Shanthi Ratnam, consultant physician and intensivist. […] Those who experience post-dengue syndrome (PDS) are likely to have symptoms such as fatigue that can range from mild to overwhelming; musculoskeletal symptoms like muscle and joint pain or swelling of the joints known as reactive arthritis; and neurological signs like poor concentration or dizziness.
  • #139
    https://www.ttsh.com.sg/Patients-and-Visitors/Pages/Find-Conditions-and-Treatments-Details.aspx?condition=Dengue+Fever-What-You-Need-To-Know-Inpatient
    – Inflammation of other organs such as the heart or brain (rare) […] […] […] If you develop any of these warning signs, please inform our doctors IMMEDIATELY: […] – Severe abdominal pain […] – Persistent vomiting […] – Vomiting blood […] – Black and tarry stools […] – Bleeding from nose or gums […] – Drowsiness or irritability […] – Pale, cold, or clammy (i.e. sweaty) skin […] – Difficulty breathing […] […] […] There are no antibiotics or anti-viral medications to treat dengue fever. Treatment includes rest and close follow-up with a doctor to monitor your condition. The main components to managing dengue fever are: […] 1. Fluid Electrolyte Replacement […] 2. Symptom Relief Fever Control […] 3. Bleeding Prevention Control […] […] […] During recovery, you may still feel very tired and weak. It is advisable to have at least a full week of rest before returning to work.
  • #140 Dengue fever – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/dengue-fever/symptoms-causes/syc-20353078
    Dengue fever causes a high fever 104 F (40 C) and any of the following signs and symptoms: […] Most people recover within a week or so. In some cases, symptoms worsen and can become life-threatening. This is called severe dengue, dengue hemorrhagic fever or dengue shock syndrome. […] Severe dengue happens when your blood vessels become damaged and leaky. And the number of clot-forming cells (platelets) in your bloodstream drops. This can lead to shock, internal bleeding, organ failure and even death. […] Warning signs of severe dengue fever which is a life-threatening emergency can develop quickly. The warning signs usually begin the first day or two after your fever goes away, and may include: […] Severe dengue fever is a life-threatening medical emergency. Seek immediate medical attention if you’ve recently visited an area in which dengue fever is known to occur, you have had a fever and you develop any of the warning signs.
  • #141 Symptoms of Dengue and Testing | Dengue | CDC
    https://www.cdc.gov/dengue/signs-symptoms/index.html
    The most common symptom of dengue is fever with any of the following: […] For people who get sick with dengue, symptoms can be mild or severe. […] Severe dengue can be life-threatening within a few hours and often requires care at a hospital. […] Symptoms of dengue typically last 27 days. […] Most people will recover after about a week. […] Symptoms of dengue can become severe within a few hours. Severe dengue is a medical emergency. […] About 1 in 20 people who get sick with dengue will develop severe dengue. Severe dengue can result in shock, internal bleeding, and death. […] Watch for warning of severe dengue. Warning signs usually begin in the 24-48 hours after fever has gone away.
  • #142 Dengue fever – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/dengue-fever/symptoms-causes/syc-20353078
    Dengue fever causes a high fever 104 F (40 C) and any of the following signs and symptoms: […] Most people recover within a week or so. In some cases, symptoms worsen and can become life-threatening. This is called severe dengue, dengue hemorrhagic fever or dengue shock syndrome. […] Severe dengue happens when your blood vessels become damaged and leaky. And the number of clot-forming cells (platelets) in your bloodstream drops. This can lead to shock, internal bleeding, organ failure and even death. […] Warning signs of severe dengue fever which is a life-threatening emergency can develop quickly. The warning signs usually begin the first day or two after your fever goes away, and may include: […] Severe dengue fever is a life-threatening medical emergency. Seek immediate medical attention if you’ve recently visited an area in which dengue fever is known to occur, you have had a fever and you develop any of the warning signs.
  • #143 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Dengue fever symptoms start to appear four to 10 days after a mosquito bite and can last three to seven days. About 1 in 20 people sick with dengue will develop severe dengue after their initial symptoms begin to fade. […] Severe dengue is a life-threatening worsening of dengue symptoms. Warning signs of severe dengue are usually seen 24 to 48 hours after your fever goes away. […] Severe dengue is a medical emergency that can be fatal. If you have dengue or live in an area where dengue is common, go to the nearest ER immediately if you experience any of these symptoms: Stomach/abdominal pain. Frequent vomiting. Throwing up blood or blood in your poop (stool). Nose bleeds or bleeding gums. Extreme tiredness, restlessness or irritability. […] Initial symptoms of dengue last three to seven days. Most people begin to feel better after this, but some have life-threatening severe dengue that requires treatment in a medical facility.
  • #144 Dengue fever – UF Health
    https://ufhealth.org/conditions-and-treatments/dengue-fever
    Dengue fever is a virus-caused disease that is spread by mosquitoes. Dengue in its mild form causes fever and a rash and lasts about a week. Severe dengue can cause shock, internal bleeding, and death. About 1 out of 20 people with dengue will develop severe dengue within a few hours after symptoms start. The main risk factor for severe dengue is a prior infection with dengue. […] Dengue fever begins with a sudden high fever, often as high as 105F (40.5C), 4 to 7 days after the infection. […] Symptoms of severe dengue can occur 24 to 48 hours after fever has gone away. Severe symptoms include: Severe stomach pain and tenderness, Vomiting often (at least 3 times in 24 hours), Bleeding from the nose or gums, Vomiting blood or passing blood in the stools or urine, Bleeding under the skin (looks like bruises), Difficulty breathing, rapid breathing, Feeling tired, restless, or irritable.
  • #145 VI Department of Health Encourages Public to Know the Symptoms of Dengue – VI Department of Health
    https://doh.vi.gov/vi-department-of-health-encourages-public-to-know-the-symptoms-of-dengue/
    VI Department of Health Encourages Public to Know the Symptoms of Dengue […] U.S. VIRGIN ISLANDS VI Health Commissioner Justa Encarnacion is encouraging the public to become familiar with the symptoms of dengue, the mosquito-borne virus, and the best courses of action for treatment. […] The most common symptom of dengue is fever with any of the following: nausea, vomiting, rash, aches, and pains (eye pain, typically behind the eyes, muscle, joint, or bone pain). Symptoms of dengue typically last two to seven days and most people will recover after about a week. […] About one (1) in 20 people who get sick with dengue will develop severe dengue, according to the CDC (Center for Disease Control). […] Severe dengue usually occurs 24 to 48 hours after a fever has passed. Symptoms include belly pain, tenderness, vomiting (at least 3 times in 24 hours), bleeding from the nose or gums, vomiting blood, or blood in the stool, feeling tired, restless, or irritable. […] If you are experiencing the symptoms of severe dengue, go to the Emergency Room or see your healthcare provider immediately, Commissioner Encarnacion said.
  • #146
    https://www.ncid.sg/News-Events/News/Pages/What-are-the-warning-signs-of-severe-dengue-infection.aspx
    The warning signs of severe dengue include bleeding in the gums or nose, blood in urine or stools, heavy menstrual bleeding, severe abdominal pain, persistent vomiting to the point that the patient cannot keep fluids down, lethargy or change in alertness, and breathlessness. […] Other things to watch out for include giddiness when standing or sitting up, decreased urine output, and a poor appetite. […] Dengue patients can suffer dehydration due to poor appetite or vomiting, or diarrhoea in some cases. […] The symptoms of dengue include fever, headache, muscle and joint aches, rashes, vomiting, easy bruising, nausea and mild bleeding from the nose or gums. […] The elderly may have less aches and pains, and may present with just tiredness, sometimes accompanied by a decrease in appetite. This makes it more challenging to diagnose dengue early and to manage it well.
  • #147 Dengue fever – UF Health
    https://ufhealth.org/conditions-and-treatments/dengue-fever
    Dengue fever is a virus-caused disease that is spread by mosquitoes. Dengue in its mild form causes fever and a rash and lasts about a week. Severe dengue can cause shock, internal bleeding, and death. About 1 out of 20 people with dengue will develop severe dengue within a few hours after symptoms start. The main risk factor for severe dengue is a prior infection with dengue. […] Dengue fever begins with a sudden high fever, often as high as 105F (40.5C), 4 to 7 days after the infection. […] Symptoms of severe dengue can occur 24 to 48 hours after fever has gone away. Severe symptoms include: Severe stomach pain and tenderness, Vomiting often (at least 3 times in 24 hours), Bleeding from the nose or gums, Vomiting blood or passing blood in the stools or urine, Bleeding under the skin (looks like bruises), Difficulty breathing, rapid breathing, Feeling tired, restless, or irritable.
  • #148 Dengue fever – UF Health
    https://ufhealth.org/conditions-and-treatments/dengue-fever
    Dengue fever is a virus-caused disease that is spread by mosquitoes. Dengue in its mild form causes fever and a rash and lasts about a week. Severe dengue can cause shock, internal bleeding, and death. About 1 out of 20 people with dengue will develop severe dengue within a few hours after symptoms start. The main risk factor for severe dengue is a prior infection with dengue. […] Dengue fever begins with a sudden high fever, often as high as 105F (40.5C), 4 to 7 days after the infection. […] Symptoms of severe dengue can occur 24 to 48 hours after fever has gone away. Severe symptoms include: Severe stomach pain and tenderness, Vomiting often (at least 3 times in 24 hours), Bleeding from the nose or gums, Vomiting blood or passing blood in the stools or urine, Bleeding under the skin (looks like bruises), Difficulty breathing, rapid breathing, Feeling tired, restless, or irritable.
  • #149
    https://www.ttsh.com.sg/Patients-and-Visitors/Pages/Find-Conditions-and-Treatments-Details.aspx?condition=Dengue+Fever-What-You-Need-To-Know-Inpatient
    – Inflammation of other organs such as the heart or brain (rare) […] […] […] If you develop any of these warning signs, please inform our doctors IMMEDIATELY: […] – Severe abdominal pain […] – Persistent vomiting […] – Vomiting blood […] – Black and tarry stools […] – Bleeding from nose or gums […] – Drowsiness or irritability […] – Pale, cold, or clammy (i.e. sweaty) skin […] – Difficulty breathing […] […] […] There are no antibiotics or anti-viral medications to treat dengue fever. Treatment includes rest and close follow-up with a doctor to monitor your condition. The main components to managing dengue fever are: […] 1. Fluid Electrolyte Replacement […] 2. Symptom Relief Fever Control […] 3. Bleeding Prevention Control […] […] […] During recovery, you may still feel very tired and weak. It is advisable to have at least a full week of rest before returning to work.
  • #150 Dengue fever – UF Health
    https://ufhealth.org/conditions-and-treatments/dengue-fever
    Dengue fever is a virus-caused disease that is spread by mosquitoes. Dengue in its mild form causes fever and a rash and lasts about a week. Severe dengue can cause shock, internal bleeding, and death. About 1 out of 20 people with dengue will develop severe dengue within a few hours after symptoms start. The main risk factor for severe dengue is a prior infection with dengue. […] Dengue fever begins with a sudden high fever, often as high as 105F (40.5C), 4 to 7 days after the infection. […] Symptoms of severe dengue can occur 24 to 48 hours after fever has gone away. Severe symptoms include: Severe stomach pain and tenderness, Vomiting often (at least 3 times in 24 hours), Bleeding from the nose or gums, Vomiting blood or passing blood in the stools or urine, Bleeding under the skin (looks like bruises), Difficulty breathing, rapid breathing, Feeling tired, restless, or irritable.
  • #151 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Most patients clinically improve during this phase, but those with substantial plasma leakage can, within a few hours, develop severe dengue. […] Patients with severe plasma leakage may have pleural effusions, ascites, hypoproteinemia, or hemoconcentration. […] Patients may appear to be well despite early signs of shock. However, once hypotension develops, systolic blood pressure rapidly declines, and irreversible shock and death may ensue despite resuscitation. […] Severe dengue is defined by dengue with any of the following clinical manifestations: severe plasma leakage leading to shock or fluid accumulation with respiratory distress; severe bleeding; or severe organ impairment such as hepatitis (elevated transaminases 1,000 IU/L), impaired consciousness, or heart impairment.
  • #152 Dengue fever – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/dengue-fever/diagnosis-treatment/drc-20353084
    Diagnosing dengue fever can be difficult because its signs and symptoms can be easily confused with those of other diseases such as chikungunya, Zika virus, malaria and typhoid fever. […] While recovering from dengue fever, drink plenty of fluids. Call your doctor right away if you have any of the following signs and symptoms of dehydration: Decreased urination, Few or no tears, Dry mouth or lips, Lethargy or confusion, Cold or clammy extremities. […] If you have severe dengue fever, you may need: Supportive care in a hospital, Intravenous (IV) fluid and electrolyte replacement, Blood pressure monitoring, Transfusion to replace blood loss. […] For dengue fever, some basic questions to ask your doctor include: What’s the most likely cause of my symptoms? What kinds of tests do I need? What treatments are available? How long will it be before I’m feeling better? Are there any long-term effects of this illness? […] Be prepared to answer questions from your doctor, such as: When did your symptoms begin? Have your symptoms been continuous or occasional? How severe are your symptoms? Does anything seem to make your symptoms better or worse?
  • #153 Symptoms of Dengue and Testing | Dengue | CDC
    https://www.cdc.gov/dengue/signs-symptoms/index.html
    The most common symptom of dengue is fever with any of the following: […] For people who get sick with dengue, symptoms can be mild or severe. […] Severe dengue can be life-threatening within a few hours and often requires care at a hospital. […] Symptoms of dengue typically last 27 days. […] Most people will recover after about a week. […] Symptoms of dengue can become severe within a few hours. Severe dengue is a medical emergency. […] About 1 in 20 people who get sick with dengue will develop severe dengue. Severe dengue can result in shock, internal bleeding, and death. […] Watch for warning of severe dengue. Warning signs usually begin in the 24-48 hours after fever has gone away.
  • #154 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The disease is classified as either dengue or severe dengue. […] Severe dengue is characterized by dengue fever accompanied by severe plasma leakage, hemorrhage, impaired consciousness, myocardial dysfunction, pulmonary dysfunction, and organ dysfunction, including transaminitis greater than 1000 IU/L. […] The treatment approach for dengue fever varies depending on the patient’s illness phase. Patients without warning signs can typically be treated as outpatients with acetaminophen and sufficient oral fluids. […] Patients presenting with warning signs of the disease, severe dengue fever, or having risk factors such as age, pregnancy status, diabetes mellitus, or those who are living alone should be evaluated for hospitalization.
  • #155 Dengue: How to keep children safe | UNICEF South Asia
    https://www.unicef.org/rosa/stories/dengue-how-keep-children-safe
    Children and infants with dengue may also become more irritable than usual and their appetite and sleep patterns may change. […] Symptoms of dengue can become severe within a few hours. If you, or your child, develops any symptoms of severe dengue, seek urgent medical attention immediately. […] Severe dengue symptoms often come after fever has gone away and include: Severe abdominal pain, Persistent vomiting, Rapid breathing, Bleeding gums or nose, Fatigue, Restlessness, Blood in vomit or stool, Being very thirsty, Pale and cold skin, Feeling weak, Sleepiness, lack of energy, or irritability. […] If your child, or anyone with suspected dengue develops any of these symptoms, it is important to seek urgent medical attention. […] Young children and particularly infants are at a higher risk of developing severe dengue illness and complications than healthy adults. This is because their immune systems are weaker. […] With quick medical attention the worst impacts of severe dengue in children can be avoided.
  • #156 It’s Not ‘Just Dengue’ When It Lasts For Months – CodeBlue
    https://vgh.pth.mybluehost.me/2024/09/its-not-just-dengue-when-it-lasts-for-months/
    Post dengue syndrome can severely affect a persons quality of life, and the experience can cause a person to get depressed, especially those who had expected that their experience with dengue would be mild. […] Simply put, Dr Shanthi draws similarities between PDS and a tsunami even though the attack has come and gone, the damage has been done, leaving behind chronic inflammation and an immune system that has become highly activated. […] Overall, Dr Shanthi said that elderly patients and those with comorbid conditions like hypertension, ischemic heart disease, obesity and autoimmune disease are more likely to experience severe dengue, which increases the likelihood of experiencing post-dengue syndrome. […] Among these, the elderly are also more likely to require high-dependency or intensive care as their health can deteriorate more quickly, with symptoms that linger for a longer period.
  • #157 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The disease is classified as either dengue or severe dengue. […] Severe dengue is characterized by dengue fever accompanied by severe plasma leakage, hemorrhage, impaired consciousness, myocardial dysfunction, pulmonary dysfunction, and organ dysfunction, including transaminitis greater than 1000 IU/L. […] The treatment approach for dengue fever varies depending on the patient’s illness phase. Patients without warning signs can typically be treated as outpatients with acetaminophen and sufficient oral fluids. […] Patients presenting with warning signs of the disease, severe dengue fever, or having risk factors such as age, pregnancy status, diabetes mellitus, or those who are living alone should be evaluated for hospitalization.
  • #158 It’s Not ‘Just Dengue’ When It Lasts For Months – CodeBlue
    https://vgh.pth.mybluehost.me/2024/09/its-not-just-dengue-when-it-lasts-for-months/
    Post dengue syndrome can severely affect a persons quality of life, and the experience can cause a person to get depressed, especially those who had expected that their experience with dengue would be mild. […] Simply put, Dr Shanthi draws similarities between PDS and a tsunami even though the attack has come and gone, the damage has been done, leaving behind chronic inflammation and an immune system that has become highly activated. […] Overall, Dr Shanthi said that elderly patients and those with comorbid conditions like hypertension, ischemic heart disease, obesity and autoimmune disease are more likely to experience severe dengue, which increases the likelihood of experiencing post-dengue syndrome. […] Among these, the elderly are also more likely to require high-dependency or intensive care as their health can deteriorate more quickly, with symptoms that linger for a longer period.
  • #159 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Most people recover from dengue fever without any lasting complications. If you have symptoms of dengue fever, you have about a 1 in 20 chance of it worsening to severe dengue. If you have severe dengue and are treated immediately at a hospital or medical facility, you have a greater than 99% chance of recovering. […] Yes. Because there are at least four versions (strains) of the dengue virus, you can get dengue more than once. You’ll usually become immune to the first strain you get sick with and cant get it again. But you can get sick with one of the other three strains after that. In fact, you’re more likely to get severely sick if you get dengue more than once.
  • #160 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The disease is classified as either dengue or severe dengue. […] Severe dengue is characterized by dengue fever accompanied by severe plasma leakage, hemorrhage, impaired consciousness, myocardial dysfunction, pulmonary dysfunction, and organ dysfunction, including transaminitis greater than 1000 IU/L. […] The treatment approach for dengue fever varies depending on the patient’s illness phase. Patients without warning signs can typically be treated as outpatients with acetaminophen and sufficient oral fluids. […] Patients presenting with warning signs of the disease, severe dengue fever, or having risk factors such as age, pregnancy status, diabetes mellitus, or those who are living alone should be evaluated for hospitalization.
  • #161 Dengue: How to keep children safe | UNICEF South Asia
    https://www.unicef.org/rosa/stories/dengue-how-keep-children-safe
    Children and infants with dengue may also become more irritable than usual and their appetite and sleep patterns may change. […] Symptoms of dengue can become severe within a few hours. If you, or your child, develops any symptoms of severe dengue, seek urgent medical attention immediately. […] Severe dengue symptoms often come after fever has gone away and include: Severe abdominal pain, Persistent vomiting, Rapid breathing, Bleeding gums or nose, Fatigue, Restlessness, Blood in vomit or stool, Being very thirsty, Pale and cold skin, Feeling weak, Sleepiness, lack of energy, or irritability. […] If your child, or anyone with suspected dengue develops any of these symptoms, it is important to seek urgent medical attention. […] Young children and particularly infants are at a higher risk of developing severe dengue illness and complications than healthy adults. This is because their immune systems are weaker. […] With quick medical attention the worst impacts of severe dengue in children can be avoided.