Arteritis tętnicy skroniowej
Zapobieganie i profilaktyka

Arteritis tętnicy skroniowej (GCA) jest stanem zapalnym naczynia, który wymaga natychmiastowej interwencji w celu zapobiegania nieodwracalnej utracie wzroku oraz powikłaniom niedokrwiennym, takim jak udary mózgu. Zaleca się stosowanie małych dawek kwasu acetylosalicylowego (81-100 mg/dobę) jako profilaktykę powikłań niedokrwiennych. Kluczowe jest szybkie rozpoznanie i natychmiastowe rozpoczęcie terapii kortykosteroidami, nawet przed potwierdzeniem diagnozy biopsją tętnicy skroniowej, która powinna być wykonana w ciągu pierwszego tygodnia, ale nie powinna opóźniać leczenia. Długotrwała terapia steroidowa wymaga profilaktyki osteoporozy poprzez suplementację wapnia (1500 mg/dobę), witaminy D3 (800 IU/dobę) oraz rozważenie bisfosfonianów (alendronian, ryzedronian). Monitorowanie aktywności choroby powinno być indywidualnie dostosowane, obejmując ocenę kliniczną, markery laboratoryjne oraz regularne badania okulistyczne.

Profilaktyka Arteritis tętnicy skroniowej

Arteritis tętnicy skroniowej (olbrzymiokomórkowe zapalenie tętnic, GCA) jest stanem zapalnym, który może prowadzić do poważnych powikłań, w tym nieodwracalnej utraty wzroku. Mimo że nie istnieje potwierdzona metoda zapobiegania rozwojowi tej choroby, możliwe jest zminimalizowanie ryzyka wystąpienia powikłań poprzez odpowiednie działania profilaktyczne.123

Kwas acetylosalicylowy w profilaktyce powikłań

Istotną rolę w profilaktyce powikłań niedokrwiennych w przebiegu arteritis tętnicy skroniowej odgrywa kwas acetylosalicylowy. Badania wskazują, że stosowanie małych dawek aspiryny (81-100 mg/dobę) może znacząco zmniejszyć ryzyko utraty wzroku oraz udarów mózgu u pacjentów z GCA.456

Retrospektywne dane przedstawione przez Neshera i współpracowników potwierdzają skuteczność małych dawek aspiryny (81 mg) w zapobieganiu powikłaniom niedokrwiennym w obszarze czaszki. Wykazano, że pacjenci, którzy otrzymywali 100 mg aspiryny przed diagnozą GCA oraz w czasie jej trwania, mieli mniej powikłań okulistycznych i naczyniowo-mózgowych.78

Mimo że rzeczywisty wpływ aspiryny może być nie w pełni określony, jest ona często zalecana jako uzupełnienie terapii steroidowej w przypadku arteritis tętnicy skroniowej.910

Szybka diagnoza i natychmiastowe leczenie

Arteritis tętnicy skroniowej jest prawdziwym stanem nagłym w okulistyce. Utrata wzroku w przebiegu tej choroby jest możliwa do zapobieżenia, jeśli pacjenci zostaną zdiagnozowani wcześnie i leczeni natychmiastowo oraz agresywnie.1112

Szybka diagnoza i niezwłoczne rozpoczęcie leczenia kortykosteroidami są kluczowe dla zapobiegania nieodwracalnej utracie wzroku. W przypadku podejrzenia GCA, leczenie powinno być rozpoczęte natychmiast, nawet przed potwierdzeniem diagnozy biopsją tętnicy skroniowej.1314

Biopsja tętnicy skroniowej nie powinna opóźniać rozpoczęcia leczenia. Procedura ta może być przeprowadzona i dostarczyć dokładnych wyników nawet w okresie od dwóch do sześciu tygodni po rozpoczęciu terapii kortykosteroidami, chociaż idealnie powinna być wykonana w ciągu pierwszego tygodnia.15

Profilaktyka powikłań związanych z długotrwałą terapią kortykosteroidową

Długotrwałe leczenie kortykosteroidami wiąże się z licznymi i potencjalnie poważnymi konsekwencjami, takimi jak cukrzyca, złamania kompresyjne kręgów, miopatia sterydowa, psychoza sterydowa oraz infekcje związane z immunosupresją.16

W celu zminimalizowania ryzyka osteoporozy indukowanej steroidami, zaleca się:

  • Przeprowadzenie wyjściowego badania gęstości kości na początku terapii17
  • Suplementację wapnia (1500 mg dziennie) i witaminy D (800 IU witaminy D3 dziennie)1819
  • Rozważenie terapii bisfosfonianami, szczególnie alendronianem i ryzedronianem, które mogą zwiększyć gęstość mineralną kości i zmniejszyć ryzyko złamań kręgów u pacjentów poddanych długotrwałej terapii glikokortykosteroidami2021

Monitorowanie i regularne badania kontrolne

Pacjenci z arteritis tętnicy skroniowej wymagają regularnego monitorowania aktywności choroby, które powinno być dostosowane do indywidualnych objawów, wyników badań klinicznych i markerów laboratorynych aktywności choroby.22

Ważne jest monitorowanie pacjentów podczas terapii kortykosteroidami, a także po zakończeniu leczenia. Lekarze powinni śledzić reakcję organizmu na leczenie, mierzyć postępy po zakończeniu terapii i upewnić się, że choroba nie nawraca.2324

Regularne badania okulistyczne są kluczowe dla wczesnego wykrywania arteritis tętnicy skroniowej. Podczas badania fizykalnego lekarz może ocenić bolesność, obrzęk lub osłabione tętno w tętnicach skroniowych, które są typowymi objawami tej choroby.2526

Modyfikacja stylu życia

Chociaż nie istnieje potwierdzona metoda zapobiegania rozwojowi GCA, modyfikacja czynników ryzyka i utrzymanie zdrowego stylu życia może pomóc zmniejszyć ryzyko rozwoju choroby:2728

  • Zaprzestanie palenia tytoniu – Istnieje związek między paleniem a zwiększonym ryzykiem rozwoju arteritis tętnicy skroniowej. Ponadto palenie może zaostrzać inne schorzenia, takie jak cukrzyca i nadciśnienie, które mogą nasilać objawy tej choroby.2930
  • Regularna aktywność fizyczna – Szczególnie korzystne w zapobieganiu arteritis tętnicy skroniowej są ćwiczenia aerobowe. Mogą one poprawić przepływ krwi, funkcję układu sercowo-naczyniowego i ogólną siłę, pomagając utrzymać zdrowie tętnic i zmniejszając ryzyko rozwoju choroby.3132
  • Zarządzanie stresem – Badania wskazują, że stres może przyczyniać się do rozwoju arteritis tętnicy skroniowej. Utrzymywanie zdrowego poziomu stresu nie tylko ma kluczowe znaczenie dla optymalnego samopoczucia, ale może również pomóc zapobiec rozwojowi choroby w niektórych przypadkach.3334

Zapobieganie powikłaniom infekcyjnym

Ze względu na immunosupresyjne działanie kortykosteroidów, pacjenci mogą być bardziej narażeni na infekcje. Zaleca się:

  • Otrzymanie wszystkich zalecanych szczepień przed rozpoczęciem terapii sterydowej35
  • Przestrzeganie zasad higieny36

Warto zauważyć, że ryzyko zapalenia płuc wywołanego przez Pneumocystis jiroveci (PJP) jest niskie u pacjentów z GCA, co nie uzasadnia rutynowego przepisywania profilaktyki PJP dla tej grupy pacjentów.3738

Edukacja pacjenta

Edukacja pacjenta odgrywa istotną rolę w zarządzaniu arteritis tętnicy skroniowej, szczególnie w zakresie kluczowych objawów ostrzegawczych, możliwych powikłań i leczenia (w tym powikłań związanych z leczeniem).39

Pacjenci powinni być świadomi możliwych skutków ubocznych leków i wiedzieć, kiedy należy skonsultować się z lekarzem. Powinni również rozumieć, że leczenie może być długotrwałe i wymaga regularnych badań kontrolnych.40

Nowe podejścia w profilaktyce Arteritis tętnicy skroniowej

W ostatnich latach obserwuje się rozwój nowych podejść w leczeniu i profilaktyce arteritis tętnicy skroniowej, które mają na celu zmniejszenie dawek kortykosteroidów i związanych z nimi działań niepożądanych.

Leki oszczędzające sterydy

Tocilizumab (przeciwciało monoklonalne przeciwko receptorowi interleukiny-6) jest skuteczną terapią oszczędzającą glikokortykosteroidy, wykazującą trwałą remisję bez glikokortykosteroidów u 56% pacjentów otrzymujących tygodniowo tocilizumab w porównaniu z 18% pacjentów otrzymujących 52-tygodniowe zmniejszanie dawki prednizonu.41

Jego zastosowanie rozszerzyło się i jest używany szerzej w początkowym leczeniu olbrzymiokomórkowego zapalenia tętnic (wraz z kortykosteroidami), szczególnie u pacjentów, którzy są narażeni na wysokie ryzyko toksyczności glikokortykosteroidów.42

Stratyfikacja pacjentów

Stratyfikacja pacjentów ułatwia wdrożenie odpowiedniego podejścia terapeutycznego dla osób z arteritis tętnicy skroniowej, mając na celu osiągnięcie remisji choroby i zapobieganie utracie wzroku i/lub rozwojowi zdarzeń niedokrwiennych.43

Leczenie powinno być dostosowane do indywidualnych potrzeb pacjenta, z uwzględnieniem objawów klinicznych, biomarkerów, wyników badań histologicznych i obrazowych, a także obecności chorób współistniejących i możliwych powikłań związanych z terapią.44

Zarządzanie GCA powinno opierać się na wspólnej decyzji pacjenta i reumatologa, z uwzględnieniem wyników leczenia, celów, skuteczności, bezpieczeństwa i kosztów.45

Podsumowanie zaleceń profilaktycznych

Mimo że nie ma znanej metody zapobiegania rozwojowi arteritis tętnicy skroniowej, można podjąć szereg działań mających na celu zmniejszenie ryzyka powikłań:

  • Stosowanie małych dawek kwasu acetylosalicylowego (81-100 mg dziennie) w celu zmniejszenia ryzyka powikłań niedokrwiennych4647
  • Szybka diagnoza i natychmiastowe rozpoczęcie leczenia kortykosteroidami w przypadku podejrzenia GCA48
  • Suplementacja wapnia (1500 mg dziennie) i witaminy D (800 IU dziennie) w celu zapobiegania osteoporozie49
  • Rozważenie terapii bisfosfonianami u pacjentów poddanych długotrwałej terapii glikokortykosteroidami50
  • Regularne monitorowanie aktywności choroby i dostosowanie terapii do indywidualnych potrzeb pacjenta51
  • Modyfikacja stylu życia, w tym zaprzestanie palenia, regularna aktywność fizyczna i zarządzanie stresem5253
  • Edukacja pacjenta na temat objawów, możliwych powikłań i znaczenia przestrzegania zaleceń terapeutycznych54

Wszelkie zmiany w widzeniu muszą być natychmiast skonsultowane z lekarzem, ponieważ większość głównych przyczyn ślepoty można leczyć, jeśli zostaną wcześnie zidentyfikowane.55

Kolejne rozdziały

Zapraszamy do dalszego czytania naszego leksykonu.

Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.

  1. 17.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Giant cell arteritis
    https://sales-demo.adam.com/content.aspx?productid=143&pid=1&gid=000448
    There is no known prevention.
  • #2 Giant cell arteritis (temporal arteritis) Guide: Causes, Symptoms and Treatment Options
    https://www.drugs.com/health-guide/giant-cell-arteritis-temporal-arteritis.html
    There is no way to prevent this disease. Vision loss (and, perhaps, other complications) may be prevented by prompt diagnosis and treatment. […] Some research suggests that low-dose aspirin may help to prevent complications of giant cell arteritis, including loss of vision. While the true impact of aspirin is uncertain, it is often recommended along with steroid therapy for this condition.
  • #3 Giant Cell Arteritis and Polymyalgia Rheumatica – familydoctor.org
    https://familydoctor.org/condition/giant-cell-arteritis-and-polymyalgia-rheumatica/
    There is no known way to prevent GCA or PMR because doctors aren’t sure what causes them. […] Your doctor may prescribe a corticosteroid medicine to treat inflammation and pain. This can help with symptoms of GCA and PMR. These medicines are taken by mouth (in pill form). Once you start taking a corticosteroid, you should feel better quickly. You may need to take this medicine for 6 months up to 2 years.
  • #4 Low-dose aspirin and prevention of cranial ischemic complications in giant cell arteritis – PubMed
    https://pubmed.ncbi.nlm.nih.gov/15077317/
    At the time of the diagnosis of GCA, 36 patients (21%) had already been receiving low-dose aspirin (100 mg/day). […] These data suggest that low-dose aspirin decreases the rate of visual loss and CVAs in patients with GCA.
  • #5 Giant Cell Arteritis (Temporal Arteritis) Treatment & Management: Approach Considerations, Alternatives to Corticosteroids, Diet and Activity
    https://emedicine.medscape.com/article/332483-treatment
    Retrospective but impressive data from Nesher and colleagues support the use of low-dose aspirin (81 mg) in patients with GCA for prevention of visual loss and stroke. […] Patients on steroid therapy may receive prophylactic treatment with the following medications: Low-dose aspirin, 81 mg per day to decrease cranial ischemic complications. […] Long-term corticosteroid therapy has frequent and potentially serious consequences, including diabetes mellitus, vertebral compression fractures, steroid myopathy, steroid psychosis, and immunosuppression-related infections. […] Given the high risk of corticosteroid-induced osteoporosis, patients should have baseline bone densitometry at the start of therapy. All patients on corticosteroids need adequate calcium and vitamin D for protection against osteoporosis (1500 mg of calcium and 800 IU of vitamin D3 daily).
  • #6 Preventing Permanent Vision Loss: The Diagnosis and Treatment of Temporal Arteritis | Consultant360
    https://www.consultant360.com/articles/preventing-permanent-vision-loss-diagnosis-and-treatment-temporal-arteritis
    Data also supports the use of 100 mg/d of aspirin as an adjunct to the steroid therapy to reduce the chance of recurrence. […] As research continues to advance regarding the cellular components and chemical mediators of the inflammatory process behind temporal arteritis, we may see advances in treatment options to allow for a reduction in the use of high-dose systemic steroids.
  • #7
    https://link.springer.com/article/10.1007/s11936-006-0007-9
    Corticosteroid treatment should start directly after suspected diagnosis. […] Low-dose aspirin reduces the risk of ophthalmologic and cardiovascular complications. […] Shows that patients who received 100 mg of aspirin before and at diagnosis of temporal arteritis had less ophthalmologic and cerebrovascular ischemic complications. Furthermore, patients who received aspirin in the first 3 months of their disease had less complications.
  • #8 Recognition and Management of Polymyalgia Rheumatica and Giant Cell Arteritis | AAFP
    https://www.aafp.org/pubs/afp/issues/2013/1115/p676.html
    Initial treatment of giant cell arteritis involves immediate initiation of high-dose corticosteroids followed by urgent referral to a rheumatologist, with additional attention given to prevention of corticosteroid-related conditions. Surveillance for osteoporosis and treatment with agents proven to increase bone mineral density and decrease fracture risk in patients with glucocorticoid-induced osteoporosis, such as alendronate and risedronate, are recommended. In addition, studies show the use of low-dose aspirin decreases cranial-ischemic complications.
  • #9 Giant cell arteritis (temporal arteritis) Guide: Causes, Symptoms and Treatment Options
    https://www.drugs.com/health-guide/giant-cell-arteritis-temporal-arteritis.html
    There is no way to prevent this disease. Vision loss (and, perhaps, other complications) may be prevented by prompt diagnosis and treatment. […] Some research suggests that low-dose aspirin may help to prevent complications of giant cell arteritis, including loss of vision. While the true impact of aspirin is uncertain, it is often recommended along with steroid therapy for this condition.
  • #10 Temporal arteritis overview – wikidoc
    https://www.wikidoc.org/index.php/Temporal_arteritis_overview
    There is no known prevention for temporal arteritis. […] Use of low-dose aspirin (81 mg) for prevention of visual loss and stroke is recommended in temporal arteritis.
  • #11
    https://bpac.org.nz/bpj/2013/june/arteritis.aspx
    Giant cell arteritis must be treated urgently, as it is associated with a significant risk of permanent visual loss, stroke, aneurysm and possible death. A low threshold for suspicion and prompt corticosteroid treatment are essential to prevent these complications. […] Whenever there is a reasonable suspicion of the condition, discuss the patient with an Ophthalmologist or Rheumatologist to organise referral for a temporal artery biopsy, and initiate same-day treatment with corticosteroids. Where there is a strong clinical suspicion of giant cell arteritis, a delay in treatment will almost always have greater consequences than an unnecessary dose of corticosteroids in someone who is later found to not to have the condition. […] If the findings from the history and examination strongly indicate giant cell arteritis, after considering possible differential diagnoses, urgent treatment and referral should be initiated. The first steps for most patients should be to provide a prescription for corticosteroids and to contact either an Ophthalmologist or Rheumatologist to organise a temporal artery biopsy.
  • #12 Giant cell arteritis (temporal arteritis)
    http://webeye.ophth.uiowa.edu/eyeforum/article/gca/index.htm
    Giant cell arteritis (GCA) is an OPHTHALMIC EMERGENCY, because it carries a high risk of severe visual loss in one or both eyes – loss which is usually PREVENTABLE. Early diagnosis is the key to correct management and prevention of visual loss. […] If there is a reasonable index of suspicion that the patient has GCA or arteritic AION, start treatment immediately. Do not wait for the results of temporal artery biopsy, because by the time the result comes, the patient may have developed irreversible visual loss in both eyes. […] GCA is the most important medical emergency in ophthalmology, because of its high risk of visual loss, which is preventable if these patients are diagnosed early and treated immediately and aggressively. Thus, in patients aged over 55 years, if symptoms and/or signs suggest GCA or they have amaurosis fugax, AION, central retinal artery occlusion, cilioretinal artery occlusion or posterior ischemic optic neuropathy, always rule out GCA first before embarking on expensive and time-consuming investigations and treatments. If GCA is suspected, treat it as an emergency with systemic corticosteroids – temporal artery biopsy can wait.
  • #13 Temporal Arteritis: Symptoms, Treatments, and Causes
    https://www.healthline.com/health/temporal-arteritis
    Temporal arteritis is an autoimmune condition in which the temporal arteries, which supply blood to the head and brain, become inflamed or damaged. Early medical care can prevent serious complications like blindness. […] The main treatment goal is to prevent permanent visual loss and suppress inflammation of the blood vessels that can cause tissue damage. […] If a doctor suspects you have temporal arteritis, treatment should begin immediately, even if test results haven’t yet confirmed the diagnosis. […] Most people with temporal arteritis continue taking corticosteroids for at least a year. Some may have to take a permanent low dose. […] Although corticosteroids are the most common and effective treatments for temporal arteritis, in certain cases, doctors may consider other treatments as add-on therapy to help taper off the use of corticosteroids such as prednisone.
  • #14 Temporal Arteritis (Giant Cell Arteritis)
    https://patient.info/eye-care/visual-problems/temporal-arteritis-giant-cell-arteritis
    See a doctor immediately if you suspect that you have temporal arteritis. People with temporal arteritis need urgent treatment with steroids. Treatment aims to prevent serious complications such as severe sight impairment which can occur soon after the disease starts. […] If temporal arteritis is suspected, treatment is usually started straightaway – even before a sample taken (a biopsy) can confirm the diagnosis. The main aim is to reduce the risk of possible complications. The second aim is to relieve the headache and any other symptoms. […] The relief of symptoms and the prevention of serious complications usually outweigh the risk of side-effects from the doses of steroids used for temporal arteritis.
  • #15
    https://bpac.org.nz/bpj/2013/june/arteritis.aspx
    The need for biopsy should never delay treatment. A biopsy can usually still be performed and provide accurate results two to six weeks after initiating corticosteroid treatment, although it should ideally be performed within one week. […] Most guidelines recommend oral prednisone 40-60 mg, once daily, for patients with giant cell arteritis, with the higher dose used in patients with ischaemic symptoms. […] For patients who already have visual loss symptoms, consult with the Ophthalmologist or Rheumatologist about the possibility of intravenous corticosteroid treatment. […] Aspirin, 100 mg, daily, should be considered for patients without contraindications as there is some evidence that it decreases the rate of visual loss and other cerebrovascular complications. […] Vitamin D supplements and advice to maintain adequate calcium intake should be given to all patients in order to limit the adverse effects of long-term prednisone treatment.
  • #16 Giant Cell Arteritis (Temporal Arteritis) Treatment & Management: Approach Considerations, Alternatives to Corticosteroids, Diet and Activity
    https://emedicine.medscape.com/article/332483-treatment
    Retrospective but impressive data from Nesher and colleagues support the use of low-dose aspirin (81 mg) in patients with GCA for prevention of visual loss and stroke. […] Patients on steroid therapy may receive prophylactic treatment with the following medications: Low-dose aspirin, 81 mg per day to decrease cranial ischemic complications. […] Long-term corticosteroid therapy has frequent and potentially serious consequences, including diabetes mellitus, vertebral compression fractures, steroid myopathy, steroid psychosis, and immunosuppression-related infections. […] Given the high risk of corticosteroid-induced osteoporosis, patients should have baseline bone densitometry at the start of therapy. All patients on corticosteroids need adequate calcium and vitamin D for protection against osteoporosis (1500 mg of calcium and 800 IU of vitamin D3 daily).
  • #17 Giant Cell Arteritis (Temporal Arteritis) Treatment & Management: Approach Considerations, Alternatives to Corticosteroids, Diet and Activity
    https://emedicine.medscape.com/article/332483-treatment
    Retrospective but impressive data from Nesher and colleagues support the use of low-dose aspirin (81 mg) in patients with GCA for prevention of visual loss and stroke. […] Patients on steroid therapy may receive prophylactic treatment with the following medications: Low-dose aspirin, 81 mg per day to decrease cranial ischemic complications. […] Long-term corticosteroid therapy has frequent and potentially serious consequences, including diabetes mellitus, vertebral compression fractures, steroid myopathy, steroid psychosis, and immunosuppression-related infections. […] Given the high risk of corticosteroid-induced osteoporosis, patients should have baseline bone densitometry at the start of therapy. All patients on corticosteroids need adequate calcium and vitamin D for protection against osteoporosis (1500 mg of calcium and 800 IU of vitamin D3 daily).
  • #18 Giant Cell Arteritis (Temporal Arteritis) Treatment & Management: Approach Considerations, Alternatives to Corticosteroids, Diet and Activity
    https://emedicine.medscape.com/article/332483-treatment
    Retrospective but impressive data from Nesher and colleagues support the use of low-dose aspirin (81 mg) in patients with GCA for prevention of visual loss and stroke. […] Patients on steroid therapy may receive prophylactic treatment with the following medications: Low-dose aspirin, 81 mg per day to decrease cranial ischemic complications. […] Long-term corticosteroid therapy has frequent and potentially serious consequences, including diabetes mellitus, vertebral compression fractures, steroid myopathy, steroid psychosis, and immunosuppression-related infections. […] Given the high risk of corticosteroid-induced osteoporosis, patients should have baseline bone densitometry at the start of therapy. All patients on corticosteroids need adequate calcium and vitamin D for protection against osteoporosis (1500 mg of calcium and 800 IU of vitamin D3 daily).
  • #19
    https://bpac.org.nz/bpj/2013/june/arteritis.aspx
    The need for biopsy should never delay treatment. A biopsy can usually still be performed and provide accurate results two to six weeks after initiating corticosteroid treatment, although it should ideally be performed within one week. […] Most guidelines recommend oral prednisone 40-60 mg, once daily, for patients with giant cell arteritis, with the higher dose used in patients with ischaemic symptoms. […] For patients who already have visual loss symptoms, consult with the Ophthalmologist or Rheumatologist about the possibility of intravenous corticosteroid treatment. […] Aspirin, 100 mg, daily, should be considered for patients without contraindications as there is some evidence that it decreases the rate of visual loss and other cerebrovascular complications. […] Vitamin D supplements and advice to maintain adequate calcium intake should be given to all patients in order to limit the adverse effects of long-term prednisone treatment.
  • #20 Recognition and Management of Polymyalgia Rheumatica and Giant Cell Arteritis | AAFP
    https://www.aafp.org/pubs/afp/issues/2013/1115/p676.html
    The mainstay of treatment is corticosteroids with a slow taper, which normally reduces symptoms rapidly. Dosing must be tailored to the patient’s symptoms and inflammatory markers because up to 13% of patients require higher initial doses. Treatment regimens include recommendations for prevention of corticosteroid-related conditions. […] Recommendations that address long-term corticosteroid complications are listed in Table 3. Studies show that use of bisphosphonates, specifically alendronate (Fosamax) and risedronate (Actonel), can increase bone mineral density and decrease vertebral fractures in patients on long-term glucocorticoid therapy. Surveillance is important. Elevated inflammatory markers do not necessarily indicate increasing corticosteroid requirements but may imply a need for further investigation.
  • #21
    https://journals.lww.com/ijo/fulltext/2021/02000/giant_cell_arteritis__its_ophthalmic.7.aspx
    I stress to them the importance of being followed closely for side-effects by their local physician, as well as in my clinic. […] So far, I have never seen any GCA patient refuse corticosteroid therapy. This is because fear of going blind is next to fear of death. […] To prevent osteoporosis, supplementation with calcium, vitamin D, and bisphosphonate therapy is indicated. […] There is no convincing evidence that ischemic manifestations occur as a direct consequence of reactive thrombocytosis in GCA, particularly with the rather moderate increases in platelets. […] This subject is discussed at length elsewhere.
  • #22 Step forward towards treat-to-target management of giant cell arteritis: patients stratification aiming to targeted remission – updated guidelines | Egyptian Rheumatology and Rehabilitation | Full Text
    https://erar.springeropen.com/articles/10.1186/s43166-024-00237-w
    Patient stratification facilitate the initiation of an appropriate management approach for patients with giant cell arteritis aiming at achieving targeted disease remission state and prevention of visual loss and/or development of ischaemic events. […] GCA management should target control of the disease symptoms, avert any damage attributed to GCA, consider any relevant comorbidities and minimize treatment associated side effects. […] GCA treatment strategy should be guided by disease stratification. This can be achieved through using clinical, biomarkers, histology, and imaging parameters as well as the presence of associated comorbidities and possible medical therapy associated complications. […] Regular follow-up and monitoring of disease activity should be tailored to the individual patients symptoms, clinical findings and disease activity laboratory measures.
  • #23 Temporal Arteritis | Connecticut Vascular Center
    https://ctvascularcenter.com/patient-education/temporal-arteritis/
    Although the exact cause of the condition is unknown, doctors believe it may be linked to the body’s autoimmune response. There’s no known prevention. However, once diagnosed, temporal arteritis can be treated to minimize your symptoms and associated complications. […] Treatment typically lasts for one to two years. It’s important that you have regular checkups with your doctor during corticosteroid therapy, as well as after you’ve finished treatment. They’ll need to monitor how your body is reacting to the treatment, measure your progress afterwards, and make sure you don’t develop the condition again, as it can be reoccurring.
  • #24 Temporal Arteritis: Symptoms, Treatments, and Causes
    https://www.healthline.com/health/temporal-arteritis
    Talk with your doctor about ways to minimize these side effects. […] You’ll still need to see your doctor for checkups once you’ve finished your course of treatment. This is because temporal arteritis can recur. […] If you have symptoms or a diagnosis of temporal arteritis, it’s important to get treatment immediately to prevent serious complications. Visual loss or blindness is the most serious complication. Other complications can include: inflammation and damage to other blood vessels in the body, development of aneurysms, including aortic aneurysms and a more rarely occurring aortic dissection, eye muscle weakness, stroke. […] Your outlook for temporal arteritis will depend on how quickly you’re diagnosed and start treatment. Untreated temporal arteritis can cause serious damage to the blood vessels in your body, and in some cases, it can be life threatening.
  • #25 Diagnosing and Treating Temporal Arteritis: An Overview
    https://conloneyeinstitute.com/understanding-temporal-arteritis/
    Regular check-ups can also be advantageous for the early detection of temporal arteritis. During a physical examination, a physician can assess for tenderness, swelling, or diminished pulse in the temporal arteries, which are usual indications of temporal arteritis. Prompt treatment, facilitated by early recognition, can help avoid complications like vision loss.
  • #26 Understanding Temporal Arteritis: Symptoms, Causes & Treatments
    https://conloneyeinstitute.com/understanding-temporal-arteritis-symptoms-causes-treatments/
    Regular check-ups can also be advantageous for the early detection of temporal arteritis. During a physical examination, a physician can assess for tenderness, swelling, or diminished pulse in the temporal arteries, which are usual indications of temporal arteritis. Prompt treatment, facilitated by early recognition, can help avoid complications like vision loss.
  • #27 Diagnosing and Treating Temporal Arteritis: An Overview
    https://conloneyeinstitute.com/understanding-temporal-arteritis/
    While there is no definitive way to prevent GCA, addressing modifiable risk factors such as smoking and maintaining a healthy lifestyle may help reduce the risk of developing the disease. Here are some steps you can take to prevent temporal arteritis potentially: […] Given the established link between smoking and a heightened likelihood of developing temporal arteritis, smoking cessation is particularly important for these patients. Moreover, smoking can exacerbate other conditions, such as diabetes mellitus and hypertension, which can aggravate the symptoms of temporal arteritis. […] Particularly beneficial in the prevention of temporal arteritis is exercise, especially aerobics. It can enhance blood supply, cardiovascular function, and overall strength, helping maintain arterial health and reducing the risk of temporal arteritis.
  • #28 Understanding Temporal Arteritis: Symptoms, Causes & Treatments
    https://conloneyeinstitute.com/understanding-temporal-arteritis-symptoms-causes-treatments/
    While there is no definitive way to prevent GCA, addressing modifiable risk factors such as smoking and maintaining a healthy lifestyle may help reduce the risk of developing the disease. Here are some steps you can take to prevent temporal arteritis potentially: […] By incorporating these practices into your lifestyle, you may be able to lower your risk of developing temporal arteritis. […] Given the established link between smoking and a heightened likelihood of developing temporal arteritis, smoking cessation is particularly important for these patients. […] Particularly beneficial in the prevention of temporal arteritis is exercise, especially aerobics. It can enhance blood supply, cardiovascular function, and overall strength, helping maintain arterial health and reducing the risk of temporal arteritis.
  • #29 Diagnosing and Treating Temporal Arteritis: An Overview
    https://conloneyeinstitute.com/understanding-temporal-arteritis/
    While there is no definitive way to prevent GCA, addressing modifiable risk factors such as smoking and maintaining a healthy lifestyle may help reduce the risk of developing the disease. Here are some steps you can take to prevent temporal arteritis potentially: […] Given the established link between smoking and a heightened likelihood of developing temporal arteritis, smoking cessation is particularly important for these patients. Moreover, smoking can exacerbate other conditions, such as diabetes mellitus and hypertension, which can aggravate the symptoms of temporal arteritis. […] Particularly beneficial in the prevention of temporal arteritis is exercise, especially aerobics. It can enhance blood supply, cardiovascular function, and overall strength, helping maintain arterial health and reducing the risk of temporal arteritis.
  • #30 Temporal Arteritis: How to Manage with 6 Natural Remedies – Dr. Axe
    https://draxe.com/health/temporal-arteritis-how-to-manage-with-6-natural-remedies/
    Temporal arteritis – Dr. Axe […] Temporal arteritis causes pain and swelling in the arteries of the head and neck. There is no clear cause and no true cure, but fast medical treatment can help prevent serious complications. […] You must continue taking steroids for as long as your healthcare provider says, since the medicine helps prevent serious complications including vision loss, stroke and death. […] Temporal arteritis treatment can improve blood vessel health. However, medications can create their own problems. Thankfully, there are natural ways you may be able to improve your overall health, manage symptoms and fight drug side effects if you have temporal arteritis. […] Smoking and even being a former smoker increase the risk of developing temporal arteritis. However, when you quit smoking, your blood vessel health improves quickly. […] To avoid getting ill more often, try some of these tips: Follow hygiene recommendations. […] Ask about supplements to boost your immune system.
  • #31 Diagnosing and Treating Temporal Arteritis: An Overview
    https://conloneyeinstitute.com/understanding-temporal-arteritis/
    While there is no definitive way to prevent GCA, addressing modifiable risk factors such as smoking and maintaining a healthy lifestyle may help reduce the risk of developing the disease. Here are some steps you can take to prevent temporal arteritis potentially: […] Given the established link between smoking and a heightened likelihood of developing temporal arteritis, smoking cessation is particularly important for these patients. Moreover, smoking can exacerbate other conditions, such as diabetes mellitus and hypertension, which can aggravate the symptoms of temporal arteritis. […] Particularly beneficial in the prevention of temporal arteritis is exercise, especially aerobics. It can enhance blood supply, cardiovascular function, and overall strength, helping maintain arterial health and reducing the risk of temporal arteritis.
  • #32 Understanding Temporal Arteritis: Symptoms, Causes & Treatments
    https://conloneyeinstitute.com/understanding-temporal-arteritis-symptoms-causes-treatments/
    While there is no definitive way to prevent GCA, addressing modifiable risk factors such as smoking and maintaining a healthy lifestyle may help reduce the risk of developing the disease. Here are some steps you can take to prevent temporal arteritis potentially: […] By incorporating these practices into your lifestyle, you may be able to lower your risk of developing temporal arteritis. […] Given the established link between smoking and a heightened likelihood of developing temporal arteritis, smoking cessation is particularly important for these patients. […] Particularly beneficial in the prevention of temporal arteritis is exercise, especially aerobics. It can enhance blood supply, cardiovascular function, and overall strength, helping maintain arterial health and reducing the risk of temporal arteritis.
  • #33 Giant Cell Arteritis: Causes, Symptoms & Treatment | Tampa General Hospital
    https://www.tgh.org/institutes-and-services/conditions/giant-cell-arteritis
    Because researchers have not yet determined what causes giant cell arteritis, at this point theres nothing you can do to prevent this condition from developing. […] However, because studies suggest that living through stressful events could potentially increase your risk of developing giant cell arteritis, you should take steps to manage your stress levels: identifying and eliminating stressors that are within your control, prioritizing healthy lifestyle habits while deprioritizing harmful ones and making time in your schedule to relax are all ways you can manage your stress levels.
  • #34 Stress and Temporal Arteritis: The Relationship, Symptoms & Treatments
    https://www.verywellmind.com/stress-and-temporal-arteritis-6834218
    Research into the connection between stress and temporal arteritis reveals that stress can contribute to the development of the condition. […] As mentioned, stress can contribute to the development of temporal arteritis. Stress can increase the risk of a flare-up occurring in people who already have the condition but have it under control. […] Maintaining healthy stress levels isnt just vital to optimal well-being. It can also help prevent the condition from developing in some instances. […] The condition can also be prevented. In cases where its stress-induced, managing your stress levels may go a long way in helping to prevent the condition from developing.
  • #35 Giant Cell Arteritis (GCA): Care Instructions | Kaiser Permanente
    https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.giant-cell-arteritis-gca-care-instructions.zc1431
    GCA is treated right away to prevent blindness. Your doctor will prescribe steroids that you take as pills. […] If you are on long-term steroids, talk to your doctor about taking a daily vitamin containing calcium and vitamin D. This can prevent bone thinning caused by the steroids. […] Make sure you get all recommended vaccines. Taking steroids can weaken your immune system, and vaccines can help protect you from getting sick.
  • #36 Temporal Arteritis: How to Manage with 6 Natural Remedies – Dr. Axe
    https://draxe.com/health/temporal-arteritis-how-to-manage-with-6-natural-remedies/
    Temporal arteritis – Dr. Axe […] Temporal arteritis causes pain and swelling in the arteries of the head and neck. There is no clear cause and no true cure, but fast medical treatment can help prevent serious complications. […] You must continue taking steroids for as long as your healthcare provider says, since the medicine helps prevent serious complications including vision loss, stroke and death. […] Temporal arteritis treatment can improve blood vessel health. However, medications can create their own problems. Thankfully, there are natural ways you may be able to improve your overall health, manage symptoms and fight drug side effects if you have temporal arteritis. […] Smoking and even being a former smoker increase the risk of developing temporal arteritis. However, when you quit smoking, your blood vessel health improves quickly. […] To avoid getting ill more often, try some of these tips: Follow hygiene recommendations. […] Ask about supplements to boost your immune system.
  • #37 Is PJP Prophylaxis Indicated in Patients With Giant Cell Arteritis or Polymyalgia Rheumatica?
    https://www.hcplive.com/view/is-pjp-prophylaxis-indicated-in-patients-with-giant-cell-arteritis-or-polymyalgia-rheumatica-
    Results of a recent study showed that the risk of pneumocystis jiroveci pneumonia (PJP) is low in patients with giant cell arteritis (GCA) and polymyalgia rheumatica (PMR), therefore discouraging the routine prescribing of PJP prophylaxis for this patient population. […] The authors concluded these data do not support routine prescribing of PJP prophylaxis for patients with GCA or PMR.
  • #38
  • #39 Step forward towards treat-to-target management of giant cell arteritis: patients stratification aiming to targeted remission – updated guidelines | Egyptian Rheumatology and Rehabilitation | Full Text
    https://erar.springeropen.com/articles/10.1186/s43166-024-00237-w
    Patients education plays a vital role in the management of GCA particularly for its key warning symptoms, possible complications and its treatment (including treatment-related complications). […] Management of GCA should be based on a shared decision between the patient and the rheumatologist, and should consider the outcome of management, targets, efficacy, safety and costs.
  • #40 Temporal Arteritis: Symptoms, Treatments, and Causes
    https://www.healthline.com/health/temporal-arteritis
    Talk with your doctor about ways to minimize these side effects. […] You’ll still need to see your doctor for checkups once you’ve finished your course of treatment. This is because temporal arteritis can recur. […] If you have symptoms or a diagnosis of temporal arteritis, it’s important to get treatment immediately to prevent serious complications. Visual loss or blindness is the most serious complication. Other complications can include: inflammation and damage to other blood vessels in the body, development of aneurysms, including aortic aneurysms and a more rarely occurring aortic dissection, eye muscle weakness, stroke. […] Your outlook for temporal arteritis will depend on how quickly you’re diagnosed and start treatment. Untreated temporal arteritis can cause serious damage to the blood vessels in your body, and in some cases, it can be life threatening.
  • #41 Giant Cell Arteritis (Temporal Arteritis) | Doctor
    https://patient.info/doctor/giant-cell-arteritis-pro
    Tocilizumab (a monoclonal antibody against the interleukin-6 receptor) is an effective glucocorticoid-sparing therapy, demonstrating sustained glucocorticoid-free remission in 56% of patients receiving weekly tocilizumab compared with 18% of patients receiving a 52-week prednisone taper. […] Its use has expanded, however, and is used more widely in the initial treatment of giant cell arteritis (alongside corticosteroids), especially in patients who are at a high risk of glucocorticoid toxicity.
  • #42 Giant Cell Arteritis (Temporal Arteritis) | Doctor
    https://patient.info/doctor/giant-cell-arteritis-pro
    Tocilizumab (a monoclonal antibody against the interleukin-6 receptor) is an effective glucocorticoid-sparing therapy, demonstrating sustained glucocorticoid-free remission in 56% of patients receiving weekly tocilizumab compared with 18% of patients receiving a 52-week prednisone taper. […] Its use has expanded, however, and is used more widely in the initial treatment of giant cell arteritis (alongside corticosteroids), especially in patients who are at a high risk of glucocorticoid toxicity.
  • #43 Step forward towards treat-to-target management of giant cell arteritis: patients stratification aiming to targeted remission – updated guidelines | Egyptian Rheumatology and Rehabilitation | Full Text
    https://erar.springeropen.com/articles/10.1186/s43166-024-00237-w
    Patient stratification facilitate the initiation of an appropriate management approach for patients with giant cell arteritis aiming at achieving targeted disease remission state and prevention of visual loss and/or development of ischaemic events. […] GCA management should target control of the disease symptoms, avert any damage attributed to GCA, consider any relevant comorbidities and minimize treatment associated side effects. […] GCA treatment strategy should be guided by disease stratification. This can be achieved through using clinical, biomarkers, histology, and imaging parameters as well as the presence of associated comorbidities and possible medical therapy associated complications. […] Regular follow-up and monitoring of disease activity should be tailored to the individual patients symptoms, clinical findings and disease activity laboratory measures.
  • #44 Step forward towards treat-to-target management of giant cell arteritis: patients stratification aiming to targeted remission – updated guidelines | Egyptian Rheumatology and Rehabilitation | Full Text
    https://erar.springeropen.com/articles/10.1186/s43166-024-00237-w
    Patient stratification facilitate the initiation of an appropriate management approach for patients with giant cell arteritis aiming at achieving targeted disease remission state and prevention of visual loss and/or development of ischaemic events. […] GCA management should target control of the disease symptoms, avert any damage attributed to GCA, consider any relevant comorbidities and minimize treatment associated side effects. […] GCA treatment strategy should be guided by disease stratification. This can be achieved through using clinical, biomarkers, histology, and imaging parameters as well as the presence of associated comorbidities and possible medical therapy associated complications. […] Regular follow-up and monitoring of disease activity should be tailored to the individual patients symptoms, clinical findings and disease activity laboratory measures.
  • #45 Step forward towards treat-to-target management of giant cell arteritis: patients stratification aiming to targeted remission – updated guidelines | Egyptian Rheumatology and Rehabilitation | Full Text
    https://erar.springeropen.com/articles/10.1186/s43166-024-00237-w
    Patients education plays a vital role in the management of GCA particularly for its key warning symptoms, possible complications and its treatment (including treatment-related complications). […] Management of GCA should be based on a shared decision between the patient and the rheumatologist, and should consider the outcome of management, targets, efficacy, safety and costs.
  • #46 Low-dose aspirin and prevention of cranial ischemic complications in giant cell arteritis – PubMed
    https://pubmed.ncbi.nlm.nih.gov/15077317/
    At the time of the diagnosis of GCA, 36 patients (21%) had already been receiving low-dose aspirin (100 mg/day). […] These data suggest that low-dose aspirin decreases the rate of visual loss and CVAs in patients with GCA.
  • #47 Giant Cell Arteritis (Temporal Arteritis) Treatment & Management: Approach Considerations, Alternatives to Corticosteroids, Diet and Activity
    https://emedicine.medscape.com/article/332483-treatment
    Retrospective but impressive data from Nesher and colleagues support the use of low-dose aspirin (81 mg) in patients with GCA for prevention of visual loss and stroke. […] Patients on steroid therapy may receive prophylactic treatment with the following medications: Low-dose aspirin, 81 mg per day to decrease cranial ischemic complications. […] Long-term corticosteroid therapy has frequent and potentially serious consequences, including diabetes mellitus, vertebral compression fractures, steroid myopathy, steroid psychosis, and immunosuppression-related infections. […] Given the high risk of corticosteroid-induced osteoporosis, patients should have baseline bone densitometry at the start of therapy. All patients on corticosteroids need adequate calcium and vitamin D for protection against osteoporosis (1500 mg of calcium and 800 IU of vitamin D3 daily).
  • #48 Giant cell arteritis (temporal arteritis)
    http://webeye.ophth.uiowa.edu/eyeforum/article/gca/index.htm
    Giant cell arteritis (GCA) is an OPHTHALMIC EMERGENCY, because it carries a high risk of severe visual loss in one or both eyes – loss which is usually PREVENTABLE. Early diagnosis is the key to correct management and prevention of visual loss. […] If there is a reasonable index of suspicion that the patient has GCA or arteritic AION, start treatment immediately. Do not wait for the results of temporal artery biopsy, because by the time the result comes, the patient may have developed irreversible visual loss in both eyes. […] GCA is the most important medical emergency in ophthalmology, because of its high risk of visual loss, which is preventable if these patients are diagnosed early and treated immediately and aggressively. Thus, in patients aged over 55 years, if symptoms and/or signs suggest GCA or they have amaurosis fugax, AION, central retinal artery occlusion, cilioretinal artery occlusion or posterior ischemic optic neuropathy, always rule out GCA first before embarking on expensive and time-consuming investigations and treatments. If GCA is suspected, treat it as an emergency with systemic corticosteroids – temporal artery biopsy can wait.
  • #49 Giant Cell Arteritis (Temporal Arteritis) Treatment & Management: Approach Considerations, Alternatives to Corticosteroids, Diet and Activity
    https://emedicine.medscape.com/article/332483-treatment
    Retrospective but impressive data from Nesher and colleagues support the use of low-dose aspirin (81 mg) in patients with GCA for prevention of visual loss and stroke. […] Patients on steroid therapy may receive prophylactic treatment with the following medications: Low-dose aspirin, 81 mg per day to decrease cranial ischemic complications. […] Long-term corticosteroid therapy has frequent and potentially serious consequences, including diabetes mellitus, vertebral compression fractures, steroid myopathy, steroid psychosis, and immunosuppression-related infections. […] Given the high risk of corticosteroid-induced osteoporosis, patients should have baseline bone densitometry at the start of therapy. All patients on corticosteroids need adequate calcium and vitamin D for protection against osteoporosis (1500 mg of calcium and 800 IU of vitamin D3 daily).
  • #50 Recognition and Management of Polymyalgia Rheumatica and Giant Cell Arteritis | AAFP
    https://www.aafp.org/pubs/afp/issues/2013/1115/p676.html
    The mainstay of treatment is corticosteroids with a slow taper, which normally reduces symptoms rapidly. Dosing must be tailored to the patient’s symptoms and inflammatory markers because up to 13% of patients require higher initial doses. Treatment regimens include recommendations for prevention of corticosteroid-related conditions. […] Recommendations that address long-term corticosteroid complications are listed in Table 3. Studies show that use of bisphosphonates, specifically alendronate (Fosamax) and risedronate (Actonel), can increase bone mineral density and decrease vertebral fractures in patients on long-term glucocorticoid therapy. Surveillance is important. Elevated inflammatory markers do not necessarily indicate increasing corticosteroid requirements but may imply a need for further investigation.
  • #51 Step forward towards treat-to-target management of giant cell arteritis: patients stratification aiming to targeted remission – updated guidelines | Egyptian Rheumatology and Rehabilitation | Full Text
    https://erar.springeropen.com/articles/10.1186/s43166-024-00237-w
    Patient stratification facilitate the initiation of an appropriate management approach for patients with giant cell arteritis aiming at achieving targeted disease remission state and prevention of visual loss and/or development of ischaemic events. […] GCA management should target control of the disease symptoms, avert any damage attributed to GCA, consider any relevant comorbidities and minimize treatment associated side effects. […] GCA treatment strategy should be guided by disease stratification. This can be achieved through using clinical, biomarkers, histology, and imaging parameters as well as the presence of associated comorbidities and possible medical therapy associated complications. […] Regular follow-up and monitoring of disease activity should be tailored to the individual patients symptoms, clinical findings and disease activity laboratory measures.
  • #52 Diagnosing and Treating Temporal Arteritis: An Overview
    https://conloneyeinstitute.com/understanding-temporal-arteritis/
    While there is no definitive way to prevent GCA, addressing modifiable risk factors such as smoking and maintaining a healthy lifestyle may help reduce the risk of developing the disease. Here are some steps you can take to prevent temporal arteritis potentially: […] Given the established link between smoking and a heightened likelihood of developing temporal arteritis, smoking cessation is particularly important for these patients. Moreover, smoking can exacerbate other conditions, such as diabetes mellitus and hypertension, which can aggravate the symptoms of temporal arteritis. […] Particularly beneficial in the prevention of temporal arteritis is exercise, especially aerobics. It can enhance blood supply, cardiovascular function, and overall strength, helping maintain arterial health and reducing the risk of temporal arteritis.
  • #53 Stress and Temporal Arteritis: The Relationship, Symptoms & Treatments
    https://www.verywellmind.com/stress-and-temporal-arteritis-6834218
    Research into the connection between stress and temporal arteritis reveals that stress can contribute to the development of the condition. […] As mentioned, stress can contribute to the development of temporal arteritis. Stress can increase the risk of a flare-up occurring in people who already have the condition but have it under control. […] Maintaining healthy stress levels isnt just vital to optimal well-being. It can also help prevent the condition from developing in some instances. […] The condition can also be prevented. In cases where its stress-induced, managing your stress levels may go a long way in helping to prevent the condition from developing.
  • #54 Step forward towards treat-to-target management of giant cell arteritis: patients stratification aiming to targeted remission – updated guidelines | Egyptian Rheumatology and Rehabilitation | Full Text
    https://erar.springeropen.com/articles/10.1186/s43166-024-00237-w
    Patients education plays a vital role in the management of GCA particularly for its key warning symptoms, possible complications and its treatment (including treatment-related complications). […] Management of GCA should be based on a shared decision between the patient and the rheumatologist, and should consider the outcome of management, targets, efficacy, safety and costs.
  • #55 Temporal Arteritis | Nursing Times
    https://www.nursingtimes.net/infection-prevention-and-control/temporal-arteritis-12-08-2003/
    Aspirin may be a useful prophylactic treatment but it is not suitable for every patient. […] As many eye conditions are asymptomatic it is essential to emphasise the importance of having regular eye tests. […] Any changes in sight must be followed up immediately as most major causes of blindness can be treated if identified at an early stage.