Materiały źródłowe

• #1 Epidemiology of uveitis in the mid-Atlantic United States | OPTH

  https://www.dovepress.com/epidemiology-of-uveitis-in-the-mid-atlantic-united-states-peer-reviewed-fulltext-article-OPTH

  Uveitis is a leading cause of visual morbidity and causes approximately 30,000 new cases of legal blindness annually in the United States alone. […] Worldwide, epidemiologic reports on uveitis have led to the identification of new entities, contributed to monitoring of shifting patterns of uveitis, and guided diagnostic and therapeutic approaches. […] In the United States, there has been increasing interest in population-based studies of uveitis, with growing recognition that demographics and regional factors affect presentation, management, and outcomes. […] This is a retrospective review of the epidemiologic features of all patients seen with uveitis over a 30-year period at the University of Virginia (UVA), a tertiary referral center for a racially diverse population, attracting patients from Virginia (VA) and neighboring states.

• #2 Is it possible to cut down the number of unknown etiology in uveitis? – Kuznetcova – Ophthalmology Reports

  https://journals.eco-vector.com/ov/article/view/16369

  Uveitis accounts for 5%15% of all ocular pathologies and occurs in 5%7% of hospitalized patients. According to authors from the Helmholtz Moscow Research Institute of Eye Diseases, uveitis accounts for 7%30% of all eye diseases, and the incidence is 0.30.5 cases per 1,000 population. […] Epidemiological data on uveitis differ significantly worldwide depending on the geographic, genetic, nutritional, and demographic factors. […] According to the American data, in particular, C.S. Foster, idiopathic uveitis (37.8%) prevailed among anterior uveitis, which is in contrast with the European results. […] Most of the studies listed lack data on eye sarcoidosis and HLA-B27-associated uveitis; however, according to international data, the latter is the leading cause of uveitis. […] The developed system of clinical instrumental diagnostics contributed to the reduction in the proportion of uveitis of unclear etiology by 3.6 times and more specific therapy for patients. To obtain a more complete epidemiological data, multicenter studies using contemporary examination methods are required.

• #3 Iritis | Treatment & Management | Point of Care

  https://www.statpearls.com/point-of-care/23764

  Anterior uveitis is the most common form of uveitis (occurring every 12 per 100 000 cases). It predominantly occurs in young and middle-aged people. In western countries, 50% to 70% of all uveitis cases are classified as anterior uveitis. Uveitis is responsible for 10% of legal blindness in the USA, and it accounts for approximately 30,000 new patients with blindness every year. The study from northern California on the epidemiology of uveitis revealed an incidence of 52.4 per 100000 persons per year and a prevalence of 115.3 per 100000 persons. […] The maximum incidence and prevalence were seen in elderly patients above 65 years and lowest in the pediatric age group. Women had a higher prevalence than men. The study from Affairs Medical Centre, Northwest Pacific, reported an incidence of 25.6 cases per 100000 persons and a prevalence of 69 per 100000 persons. The study in the elderly population from the care survey medicare cohort revealed an incidence of uveitis ranging from 302-424 per 100000 persons per year and an average of 340.9 per 100000. The mean incidence of uveitis was 243.6 per 100000. The reported incidence of posterior uveitis was 76.6 per 100000, and panuveitis incidence was 41.7 per 100000.

• #4 Uveitis | Doctor

  https://patient.info/doctor/uveitis-pro

  Anterior uveitis is the most common form in the UK. […] The prevalence of uveitis is variously given as 25-50 per 100,000 persons, with the mean onset at 30.7 years of age. […] Most people who develop uveitis are aged 20-50 years. […] Roughly 5% to 10% of these cases occur in children under the age of 16. […] The epidemiology of uveitis varies with geographical location. Finland has one of the highest incidences of uveitis and this is thought to be because of the high frequency of HLA-B27 spondylopathy amongst the population. […] Racial predisposition is related to the patient’s underlying systemic disease (eg, HLA-B27 positivity in Caucasians, Behet’s disease in individuals of Mediterranean origin).

• #5 Traumatic Iritis – EyeWiki

  https://eyewiki.org/Traumatic_Iritis

  Trauma is one of the most common causes of anterior uveitis. […] The incidence of iritis is estimated at 12 per 100,000 in the United States. […] Iritis accounts for 90% of uveitis. […] Traumatic iritis accounts for 20% of iritis. […] Younger patients are affected more than older patients. […] Males tend to be affected more than females.

• #6 Rebound Iritis following Cataract Surgery – EyeWiki

  https://eyewiki.org/Rebound_Iritis_following_Cataract_Surgery

  Rebound Iritis following cataract surgery, while uncommon, is an important consideration in a country where more than 1 million cataracts are repaired annually. […] In one study, the overall incidence of post-operative iritis specifically was 1.20% with the exclusion of patients with prior ocular inflammation or pre-existing systemic inflammatory or autoimmune diagnosis. […] The incidence was higher in patients of African American descent. […] Other risk factors included diabetes and the use of pupil expansion device during surgery. […] Overall, the incidence of iritis is approximately 12 per 100,000 in the U.S. […] Iritis is by far the most common form of uveitis, comprising approximately 90% of all uveitis cases. […] In broad terms of uveitis, post-procedural uveitis encompasses 10% of total cases, with 48.7% of those specifically following cataract extraction and IOL (intraocular lens) implantation.

• #7 Pulsenotes | Uveitis

  https://app.pulsenotes.com/specialities/ophthalmology/notes/uveitis

  Anterior uveitis is the most common form seen in 90% of cases in the Western world. […] Uveitis can occur at any age but is more common in patients 20-50 years old. The annual incidence of uveitis is estimated at 12 per 100,000 population. However, differences in incidence, prevalence, and gender distribution depend on the underlying cause. Worldwide, uveitis is a major cause of visual impairment, particularly in the developing world.

• #8 Iritis and Uveitis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1209505-overview

  Uveitis is defined as inflammation of the uveal tract, which is further subdivided into anterior and posterior components. […] Uveitis, particularly posterior uveitis, is a common cause of preventable blindness, so it is deemed a sight-threatening condition. […] The approximate estimated annual incidence of uveitis in the United States ranges from 25-52 cases per 100,000 persons per year. […] The incidence and prevalence of uveitis vary widely internationally. […] Racial predisposition to uveitis is related to the patient’s underlying systemic disease. […] In general, uveitis has no sexual predisposition except in cases secondary to autoimmune diseases, which are more common in women compared to men. […] Most people who develop uveitis are aged 20 to 50 years. […] Uveitis has been reported to be responsible for 5-20% of total blindness in Europe and North America and up to 25% of blindness in the developing world. […] Generally, the prognosis for iritis and uveitis is good with appropriate treatment.

• #9 Uveitis: The Collaborative Diagnostic Evaluation | AAFP

  https://www.aafp.org/pubs/afp/issues/2014/1115/p711.html

  The annual incidence of uveitis in North America ranges from 17 to 52 per 100,000 persons, and the prevalence ranges from 58 to 115 per 100,000 persons. […] Up to 35% of patients with uveitis have severe visual impairment, and roughly 10% are legally blind. […] Uveitis can occur at any age, but the peak incidence is between 20 and 59 years of age. […] Systemic diseases most often associated with uveitis in North America are the seronegative spondyloarthropathies, sarcoidosis, syphilis, rheumatoid arthritis, and reactive arthritis.

• #10 Uveitis | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/uveitis?lang=us

  Incidence estimates vary widely, with one meta-analysis suggesting a pooled incidence of 50.45 per 100,000 (with individual studies estimating as high as 340.9 per 100,000 per year) 2. […] Uveitis refers to inflammation of the uveal tract, which may be idiopathic, infective or inflammatory 1. It is a sight threatening condition that requires urgent ophthalmologist review.

• #11 Uveitis epidemiology and demographics – wikidoc

  https://www.wikidoc.org/index.php/Uveitis_epidemiology_and_demographics

  Worldwide, the prevalence of uveitis ranges from 69 to 204 per 100,000 persons. […] The worldwide incidence of uveitis ranges from 17 to 52 per 100,000 persons per year. […] The epidemiologic data varies greatly by underlying etiology or classification of uveitis. […] The age, sex, and race distribution of uveitis is dictated by the prevalence of the underlying cause within those demographic groups. […] Women are more commonly affected with uveitis than men. […] The prevalence of different etiologies of uveitis vary by race.

• #12 Intermediate uveitis – Wikipedia

  https://en.wikipedia.org/wiki/Intermediate_uveitis

  Although intermediate uveitis can develop at any age, it primarily afflicts children and young adults. There is a bimodal distribution with one peak in the second decade and another peak in the third or fourth decade. […] In the United States the proportion of patients with intermediate uveitis is estimated to be 4-8% of uveitis cases in referral centers. The National Institutes of Health reports a higher percentage (15%), which may indicate improved awareness or the nature of the uveitis referral clinic. In the pediatric population, intermediate uveitis can account for up to 25% of uveitis cases.

• #13 Tubulointerstitial nephritis and uveitis (TINU syndrome) – UpToDate

  https://www.uptodate.com/contents/tubulointerstitial-nephritis-and-uveitis-tinu-syndrome

  TINU is a rare syndrome. Most patients with TINU are adolescents and young women, with a median age of 15 years. It has also been reported in older adults. All series report a female-to-male predominance, with no particular racial affinity.

• #14 “Infectious uveitis: a comprehensive systematic review of emerging trends and molecular pathogenesis using network analysis” | Journal of Ophthalmic Inflammation and Infection | Full Text

  https://joii-journal.springeropen.com/articles/10.1186/s12348-024-00444-8

  Understanding the epidemiology, clinical manifestations, molecular mechanisms and treatment principles of infectious uveitis is essential for ophthalmologists and healthcare providers to effectively manage this sight-threatening condition and preserve visual function in affected individuals. […] The data indicates that acute, non-granulomatous anterior cyclitis and iritis in the anterior region are the most prevalent forms of uveitis, i.e. 53%. […] Infectious uveitis is relatively rare in individuals under 10 years old and those over 70. […] Understanding these trends is vital for healthcare professionals in diagnosing, treating, and managing infectious uveitis.

• #14 “Infectious uveitis: a comprehensive systematic review of emerging trends and molecular pathogenesis using network analysis” | Journal of Ophthalmic Inflammation and Infection | Full Text

  https://joii-journal.springeropen.com/articles/10.1186/s12348-024-00444-8

  The prevalence of infectious uveitis exhibits significant variations influenced by various factors such as geographic location, environmental conditions, socioeconomic status, genetic predispositions, and histopathological characteristics. Notably, infectious uveitis accounts for up to 25% of cases of visual impairment in developing countries. […] The estimated global prevalence rate of infectious uveitis gathered from previous studies is illustrated in Fig. 3. The global map revealing the prevalence of infectious uveitis highlights significant cases in specific regions, notably North and South America, Africa, and certain Asian countries. […] The high prevalence in these areas highlights the urgent need for targeted interventions, including enhanced public health initiatives, improved access to medical care, and comprehensive strategies.

• #15 Uveitis | Treatment & Management | Point of Care

  https://www.statpearls.com/point-of-care/30914

  Uveitis can affect people of all ages and can vary significantly by geographic location and age of the patient. In a study done from 2006 to 2007, the incidence of uveitis was 24.9 cases per 100,000 persons. Prevalence rates for 2006 and 2007 came in at 57.5 and 58 respectively per 100,000 persons. There was no difference in the incidence rate between men and women, but women had a higher prevalence. Anterior uveitis is the most prevalent form, accounting for approximately 50% of uveitis cases, while posterior uveitis is the least common. Ongoing inflammation seen in untreated uveitis and complications related to this uncontrolled inflammation are estimated to be responsible for approximately 10% of the blindness in the United States. […] Infectious processes are thought to account for approximately 20% of all uveitis cases but underlying causes can vary geographically.

• #16 Epidemiology of uveitis in the mid-Atlantic United States | OPTH

  https://www.dovepress.com/epidemiology-of-uveitis-in-the-mid-atlantic-united-states-peer-reviewed-fulltext-article-OPTH

  Our study had a higher proportion of African American patients (n=134 [27%]) than reported in most other studies. […] The percentage of patients with sarcoidosis varies based on region: studies report 5% or less in Portugal, Portland, University of South California, and Iowa; 9% in Amsterdam, and 11% at Duke. […] We compared race and sex data for each entity with the race or sex distributions of our uveitis population as a whole. […] Most (32.1%) of our patients had a chronic onset of uveitis. […] The frequencies for various forms of uveitis in our study were similar to those of many previous studies; for example, reported rates of anterior uveitis in previous studies ranged from 27.8% to 72%. […] In our study, the proportion of patients with uveitis for whom a diagnosis could be made was 68.2%.

• #16 Epidemiology of uveitis in the mid-Atlantic United States | OPTH

  https://www.dovepress.com/epidemiology-of-uveitis-in-the-mid-atlantic-united-states-peer-reviewed-fulltext-article-OPTH

  Uveitis is a leading cause of visual morbidity and causes approximately 30,000 new cases of legal blindness annually in the United States alone. […] Worldwide, epidemiologic reports on uveitis have led to the identification of new entities, contributed to monitoring of shifting patterns of uveitis, and guided diagnostic and therapeutic approaches. […] In the United States, there has been increasing interest in population-based studies of uveitis, with growing recognition that demographics and regional factors affect presentation, management, and outcomes. […] This is a retrospective review of the epidemiologic features of all patients seen with uveitis over a 30-year period at the University of Virginia (UVA), a tertiary referral center for a racially diverse population, attracting patients from Virginia (VA) and neighboring states.

• #17 Iritis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/iritis/symptoms-causes/syc-20354961

  Iritis is the most common type of uveitis. Uveitis is inflammation of part of or all of the uvea. The cause is often unknown. It can result from an underlying condition or genetic factor. […] See an eye specialist (ophthalmologist) as soon as possible if you have symptoms of iritis. Prompt treatment helps prevent serious complications. […] Your risk of developing iritis increases if you: Have a specific genetic alteration. People with a specific change in a gene that’s essential for healthy immune system function are more likely to develop iritis. This change is labeled HLA-B27. […] If not treated properly, iritis could lead to: Glaucoma. Recurrent iritis can result in glaucoma, a serious eye condition characterized by increased pressure inside the eye and possible vision loss.

• #18 Epidemiology of uveitis in a US population-based study | Journal of Ophthalmic Inflammation and Infection | Full Text

  https://joii-journal.springeropen.com/articles/10.1186/s12348-018-0148-5

  Of the 5106 participants, 27 had reported a diagnosis of uveitis, showing an adjusted prevalence of 5.4 per 1000 subjects (95% CI 3.48.5/1000). […] The purpose of our present study is to determine the association between self-reported uveitis in an adult American population and potential demographic and clinical risk factors, as well as the prevalence of the disease in the USA, using a nationwide database. […] In our US population-based study using the NHANES database, we found that AS, cigarette smoking, and higher age were positively associated to self-reported uveitis. […] Given that all analyses on our population-based study accounted for the multi-stage nature of NHANES, these results are nationally representative, and thus, we can extrapolate them in order to obtain an estimate of the actual prevalence of the disease in the country, which is of 5.4 per 1000 residents (95% CI 3.48.5/1000). […] Our present study also demonstrates that a positive history of cigarette smoking is associated with higher odds of a uveitis diagnosis.

• #19 Fuchs’ uveitis syndrome: a 20-year experience in 466 patients | Scientific Reports

  https://www.nature.com/articles/s41598-024-59393-w

  Fuchs uveitis syndrome (FUS) also known as Fuchs heterochromic iridocyclitis, is a chronic form of uveitis characterized by mild inflammation typically in one eye, often asymptomatic during routine ocular examinations. […] FUS ranks as the second most common non-infectious uveitis in some reports. While the incidence of FUS spans between 1.8 and 22.7% in developed countries, it remains lower, ranging from 0 to 5.6%, in developing nations. […] Epidemiologic studies with a relatively considerable number of patients for FUS in Iran are scarce. […] The current study demonstrated several differences between Iranian FUS patients and others, including clinical features, misdiagnosis patterns, and concurrent diseases.

• #20 Approach to multiple sclerosis associated uveitis: 3 case reports

  https://www.openaccessjournals.com/articles/approach-to-multiple-sclerosis-associated-uveitis-3-case-reports-12909.html

  Uveitis which is known as inflammation in adjacent ocular structures can be one of the ocular manifestations of multiple sclerosis. It is shown that the prevalence of uveitis in patients suffering from MS is more than the normal population. […] The association between MS and uveitis has been reported in different publications. For example, Tola et al studied 110 patients who suffered from MS and estimated that the prevalence of uveitis was nearly 36 percentages (n=40). […] It is claimed that the prevalence of uveitis in MS is significantly higher than in general population in which the incidence of uveitis has been estimated between 17 and 52 per 100 000 of population per year, and the prevalence as 38-714 cases per 100 000 of the population. […] In an epidemiologic study on uveitis which was designed by Soheilian et al in Iran, sarcoidosis (7.3%) and MS (4.2%) were regarded as two most common systemic diseases, which were related to intermediate uveitis.

• #21 Uveitis: Laboratory Testing and Current Recommendations

  https://journalofmedicaloptometry.com/volume1-issue2/uveitis-laboratory-investigations-and-current-recommendations-on-diagnosis/

  Uveitis is defined by inflammation of the iris, ciliary body, choroid, retina or vitreous. It is the third leading cause of blindness worldwide and encompasses approximately 10% of preventable vision loss in the United States. The prevalence of uveitis in the US is around 38 cases per 100,000 and has an incidence of 15 cases per 100,000. However, the epidemiology can differ considerably depending on geographic location, race, age, and genetics. Untreated uveitis can be sight-threatening due to secondary complications such as macular edema, glaucoma and retinal ischemia. […] Currently, there is no standard approach for laboratory investigations in patients with uveitis. There are differing opinions on which baseline testing is most valuable and what follow-up testing yields the highest diagnostic rates.

• #21 Uveitis: Laboratory Testing and Current Recommendations

  https://journalofmedicaloptometry.com/volume1-issue2/uveitis-laboratory-investigations-and-current-recommendations-on-diagnosis/

  When determining which tests will yield the highest rate of return, it is helpful to understand which underlying conditions are most common in the specific category of uveitis and geographic location. […] In 2017, Sve et al. published a literature review of current recommendations describing the diagnostic work-up of a uveitis patient. First, they concluded diagnosis should be heavily weighed on the medical history and clinical examination of the patient. Second, syphilis screening should be performed in all cases. Third, further diagnostic testing should be based on the specific anatomical classification. […] Their recommendations are illustrated below in Table 4. They recommended minimal first-line tests for all types of uveitis should include complete blood count (CBC), erythrocyte sedimentation rate (ESR), c-reactive protein (CRP), Tuberculin skin test, Syphilis serology, and chest x-ray. […] If sarcoidosis is suspected, ACE may help point to the diagnosis. However, keep in mind its variability and fair predictive value. Tests evaluating specific disease processes can be ordered judiciously when clinical examination, uveitis classification and differentials are considered.

• #22 Uveitic glaucoma – Wikipedia

  https://en.wikipedia.org/wiki/Uveitic_glaucoma

  Uveitic glaucoma is most commonly a progression stage of noninfectious anterior uveitis or iritis. […] Approximately 30% of uveitis patients develop glaucoma as a result of the inflammation that occurs in uveitis, as a complication of steroid treatment or a combination of both. […] Based on epidemiological studies of uveitis, approximately 34-94/100,000 people will develop uveitic glaucoma. […] About 30% of uveitis patients also develop uveitic glaucoma. Uveitic glaucoma patients are at significantly higher risk for visual field loss in the long term compared to patients who only have uveitis.

• #23 Epidemiology of Uveitis in a Nigerian Tertiary Eye Care Centre

  https://scholars.direct/Articles/opthalmology/joroc-3-010.php?jid=opthalmology

  The knowledge of region specific variation in pattern is essential in determining final diagnosis as well as in health planning. […] Early diagnosis and adequate treatment can help to reduce or prevent damage in many uveitis entities. […] Uveitis is a common condition with risk of ocular morbidity.

• #24 SciELO Brazil – Análise retrospectiva e caracterização epidemiológica dos casos de uveíte em hospital terciário Análise retrospectiva e caracterização epidemiológica dos casos de uveíte em hospital terciário

  https://www.scielo.br/j/rbof/a/VpSfwdV66VCxLfL8mTHyH5p/?lang=en

  Epidemiological studies about uveitis are usually made in tertiary hospitals, which do not reflect the epidemiological profile of population in general. […] Epidemiological studies on the incidence of uveitis are important for the planning of health actions, since they contribute to the establishment of the pattern of diseases, which is quite heterogeneous and vary according to the place and time. […] Epidemiological studies dealing with uveitis are mostly carried out in tertiary centers, which could be associated to a referral bias, that is, the presence of rheumatologic services in these hospitals and the ease of direct referral to Ophthalmology could increase the rate of rheumatological etiologies in the sample, thus not reflecting the prevalence found in the general population. […] The present retrospective study analyzed the distribution of cases of uveitis in a tertiary service, allowing a high prevalence of anterior uveitis, especially those of rheumatological origin, to be observed, unlike previous reports in the literature in underdeveloped countries, thus resembling more the profile found in developed countries.

• #25

  https://link.springer.com/article/10.1007/s10792-023-02772-5

  To analyse the demography, etiology, and classification of uveitis at a tertiary academic referral center. […] This study aimed to investigate the epidemiological profile of patients, including their demographics and the main etiologic factors of uveitis. […] The incidence of uveitis in the United States and Europe is estimated to be approximately 2050/100,000 per year, and prevalence is estimated to be in the order of 38-714/100000 population. […] Recording patterns of uveitis within a population is essential for understanding its epidemiological profile, which may be useful for improving clinical practices. […] Our study is the first major epidemiological approach of uveitis in Greece over the last 30 years and one of the largest single-center uveitis studies in the literature to date.

• #26

  https://journals.lww.com/apjoo/fulltext/2021/02000/big_data_based_epidemiology_of_uveitis_and_related.9.aspx

  Large administrative health databases, nationwide surveys, and the widespread adoption of electronic medical records have led to an increasing availability of health-related data on ocular inflammatory disease, allowing us to elucidate the real-world epidemiology of uveitis and examine patient and systems-level risk factors for the incidence of specific etiologies of uveitis and its complications. […] Despite limitations inherent to the large datasets currently available for studying uveitis, big data analyses have enabled a greater understanding of the real-world epidemiology and treatment patterns associated with ocular inflammation. […] These large datasets enable us to elucidate the real-world epidemiology of uveitis, and to examine patient and systems-level risk factors for the incidence of specific etiologies of uveitis and its complications.

• #27 Uveitis Literature Unclear on Extent of Disease

  https://www.reviewofoptometry.com/article/little-consensus-in-uveitis-literature

  Uveitis poses a serious public health concern, but, compared with its impact, what we know about this inflammatory disease is disproportionally small. […] Experts note that its epidemiology is unclear, and its classification is difficult because its multiple presenting characteristics and signs are tough to identify. […] To estimate the prevalence and incidence of uveitis, researchers conducted a systematic review of the Medline, Embase and Cochrane databases for all time up to January 2019. […] They found wide variation in population-based estimates of uveitis epidemiology and noted that the conclusiveness of these studies was limited. […] Data ranged from nine to 730 cases per 100,000. Incidence studies turned up a pooled incidence of 50.45 per 100,000 people. […] The researchers wrote that geographic region was an important explanatory factor for the variability among the studies.

• #27 Uveitis Literature Unclear on Extent of Disease

  https://www.reviewofoptometry.com/article/little-consensus-in-uveitis-literature

  Based on the results obtained in this systematic review, its very difficult to draw definitive conclusions, the researchers wrote. […] The studies analyzed present a variable methodology, which hampers obtaining unified figures of prevalence and incidence of uveitis. […] They stressed the importance of studying different etiologies to establish a map of the real care needs of uveitis patients.

• #28 Is it possible to cut down the number of unknown etiology in uveitis? – Kuznetcova – Ophthalmology Reports

  https://journals.eco-vector.com/ov/article/view/16369

  Uveitis accounts for 5%15% of all ocular pathologies and occurs in 5%7% of hospitalized patients. According to authors from the Helmholtz Moscow Research Institute of Eye Diseases, uveitis accounts for 7%30% of all eye diseases, and the incidence is 0.30.5 cases per 1,000 population. […] Epidemiological data on uveitis differ significantly worldwide depending on the geographic, genetic, nutritional, and demographic factors. […] According to the American data, in particular, C.S. Foster, idiopathic uveitis (37.8%) prevailed among anterior uveitis, which is in contrast with the European results. […] Most of the studies listed lack data on eye sarcoidosis and HLA-B27-associated uveitis; however, according to international data, the latter is the leading cause of uveitis. […] The developed system of clinical instrumental diagnostics contributed to the reduction in the proportion of uveitis of unclear etiology by 3.6 times and more specific therapy for patients. To obtain a more complete epidemiological data, multicenter studies using contemporary examination methods are required.

• #29

  https://link.springer.com/article/10.1007/s10384-020-00809-1

  To investigate the epidemiology of uveitis in Japan and assess its changes over time. […] Sixty-six hospitals in Japan with uveitis specialty clinics participated in this retrospective nationwide survey. […] In 2016, new patients with uveitis accounted for 3.2% of the total number of new patients with ophthalmic diseases. […] A total of 5378 patients were enrolled in the survey; 3408 cases could be classified with a specific uveitis entity, and 1970 cases were described as unclassified intraocular inflammation. […] Some changes were observed between the previous nationwide surveys (2002 and 2009) and the present survey. It must be valuable to continue such nationwide epidemiologic surveys at regular intervals.

• #30 Reducing the risk of visual disability for children with juvenile idiopathic arthritis uveitis through disease surveillance: past and future challenges | Pediatric Rheumatology | Full Text

  https://ped-rheum.biomedcentral.com/articles/10.1186/s12969-024-01037-4

  Childhood blindness significantly impacts development, education, employment, and mental health, creating burden for families and society. […] Alongside the use of disease-modifying agents and anti-TNF immunomodulators, JIAU surveillance has helped to reduce the risk of JIAU related blindness. […] The Multinational Interdisciplinary Working Group for Uveitis in Childhood (MIWGUC) has brought some much-needed standardisation to JIA surveillance, developing a consensus-based screening proposal which simplifies the protocol, supporting implementation amongst non-specialists, and ensuring that children at risk receive the timely eye examination necessary to avoid life-changing visual disability. […] Attempts by supranational groups, such as the Multinational Interdisciplinary Working Group for Uveitis in Childhood (MIWGUC), to standardise uveitis surveillance should support health care professionals in delivering appropriate care to children in need.

• #30 Reducing the risk of visual disability for children with juvenile idiopathic arthritis uveitis through disease surveillance: past and future challenges | Pediatric Rheumatology | Full Text

  https://ped-rheum.biomedcentral.com/articles/10.1186/s12969-024-01037-4

  Effective surveillance for uveitis in JIA is essential to prevent visual disability. […] Standardised timetables should support consistency and enhance care quality. […] Integrated imaging and the adoption of uniform screening guidelines globally will be key to improving outcomes for children with JIA.

• #31 Incidence, prevalence, and risk factors of infectious uveitis and scleritis in the United States: A claims-based analysis | PLOS One

  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0237995

  Our findings indicate that the incidence and prevalence of infectious ocular inflammation are higher than previously estimated in the United States. Raising awareness about specific demographic and SES factors that confer increased risk for infectious uveitis/scleritis represents an important opportunity to improve diagnosis and treatment of this potentially blinding condition.

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