Choroba zastawki aorty
Leczenie
Leczenie choroby zastawki aorty wymaga indywidualnego podejścia, uwzględniającego stopień zaawansowania schorzenia, obecność objawów oraz ogólny stan pacjenta. W początkowych stadiach, przy łagodnych lub bezobjawowych postaciach, stosuje się postępowanie zachowawcze obejmujące regularne kontrole echokardiograficzne, modyfikację stylu życia oraz farmakoterapię (inhibitory ACE, beta-blokery, diuretyki, leki przeciwarytmiczne, przeciwzakrzepowe i statyny). W przypadku ciężkiej dysfunkcji zastawki, zwłaszcza z objawami lub frakcją wyrzutową lewej komory <50%, wskazane jest leczenie zabiegowe. Dostępne metody to chirurgiczna wymiana zastawki aorty (SAVR) oraz przezcewnikowa wymiana zastawki (TAVR), z wyborem zależnym od wieku, ryzyka operacyjnego i preferencji pacjenta. SAVR trwa około 4 godzin, wymaga znieczulenia ogólnego i hospitalizacji 5-7 dni, natomiast TAVR to procedura około 1-godzinna, często bez znieczulenia ogólnego, z krótszym pobytem szpitalnym (1-2 dni) i szybszą rekonwalescencją (około 1 tygodnia). Zastawki mechaniczne stosowane w SAVR cechują się dłuższą trwałością, ale wymagają dożywotniej antykoagulacji, natomiast biologiczne, używane w TAVR, mają trwałość 10-15 lat i nie wymagają stałej antykoagulacji.
- Leczenie choroby zastawki aorty – wprowadzenie
- Leczenie zachowawcze choroby zastawki aorty
- Leczenie zabiegowe choroby zastawki aorty
- Naprawa zastawki aorty
- Operacyjna wymiana zastawki aorty (SAVR)
- Przezcewnikowa wymiana zastawki aorty (TAVR/TAVI)
- Specjalistyczne procedury naprawy i wymiany zastawki aorty
- Wybór optymalnej metody leczenia
- Postępowanie po interwencji zastawkowej
- Wyniki leczenia i rokowanie
Leczenie choroby zastawki aorty – wprowadzenie
Leczenie choroby zastawki aorty zależy od kilku kluczowych czynników, takich jak: stopień zaawansowania choroby, obecność objawów, postęp schorzenia oraz ogólny stan zdrowia pacjenta. Choroba zastawki aorty wymaga kompleksowego podejścia i powinna być leczona przez wielodyscyplinarny zespół specjalistów, w skład którego wchodzą kardiolodzy, kardiochirurdzy, kardiolodzy interwencyjni oraz specjaliści od obrazowania serca, którzy wspólnie opracowują optymalny plan leczenia dostosowany do indywidualnych potrzeb pacjenta.123
W początkowym stadium choroby zastawki aorty, gdy objawy są łagodne lub nie występują, postępowanie może ograniczać się do regularnych kontroli lekarskich, zmian stylu życia oraz farmakoterapii. Jednakże w przypadku cięższych stadiów choroby lub pojawienia się objawów, często konieczna jest interwencja chirurgiczna w celu naprawy lub wymiany uszkodzonej zastawki aorty. W pewnych przypadkach operacja może być zalecana nawet przy braku wyraźnych objawów, aby zapobiec postępowi choroby i potencjalnym powikłaniom.124
Leczenie zachowawcze choroby zastawki aorty
W przypadku łagodnej lub umiarkowanej choroby zastawki aorty, gdy objawy nie występują lub są minimalne, postępowanie zachowawcze może być wystarczające. Pacjenci z bezobjawową chorobą zastawki aorty wymagają regularnych kontroli lekarskich, w tym okresowych badań echokardiograficznych, aby monitorować progresję choroby.56
Modyfikacja stylu życia
Zdrowy styl życia może pomóc w kontrolowaniu objawów choroby zastawki aorty oraz zmniejszeniu ryzyka powikłań. Zalecenia obejmują:57
- Zdrową dietę bogatą w owoce, warzywa i produkty pełnoziarniste
- Regularne ćwiczenia fizyczne, dostosowane do możliwości pacjenta
- Utrzymanie prawidłowej masy ciała
- Zaprzestanie palenia tytoniu
- Ograniczenie spożycia alkoholu i soli
Farmakoterapia
Choć leki nie mogą wyleczyć choroby zastawki aorty, mogą pomóc w kontrolowaniu objawów i zmniejszeniu ryzyka powikłań. Farmakoterapia może obejmować:89510
- Leki obniżające ciśnienie krwi (inhibitory ACE, beta-blokery) – zmniejszają obciążenie serca i poprawiają przepływ krwi
- Leki moczopędne (diuretyki) – usuwają nadmiar płynów z organizmu, zmniejszając obciążenie serca
- Leki przeciwarytmiczne – pomagają kontrolować zaburzenia rytmu serca
- Leki przeciwzakrzepowe – zapobiegają powstawaniu zakrzepów i zatorów
- Statyny – mogą spowolnić postęp zwapnienia zastawki aorty
Należy podkreślić, że farmakoterapia nie jest metodą leczenia przyczynowego choroby zastawki aorty, a jedynie sposobem na łagodzenie objawów i kontrolowanie czynników ryzyka. W większości przypadków zaawansowanej choroby zastawki aorty konieczne będzie leczenie zabiegowe.2911
Leczenie zabiegowe choroby zastawki aorty
W przypadku znacznej dysfunkcji zastawki aorty, szczególnie gdy pojawiają się objawy, konieczne jest leczenie zabiegowe. Dostępne są różne metody interwencji, od tradycyjnych operacji na otwartym sercu po mniej inwazyjne zabiegi przezskórne.112
Naprawa zastawki aorty
Naprawa zastawki aorty, zamiast jej wymiany, jest preferowaną opcją leczenia, szczególnie u młodszych pacjentów, ponieważ pozwala zachować własną tkankę zastawki, co może poprawić długoterminowe wyniki. Operacja naprawcza zastawki aorty może obejmować następujące techniki:121314
- Separacja zrośniętych płatków zastawki
- Wzmocnienie podstawy zastawki
- Zmiana kształtu lub usunięcie nadmiaru tkanki zastawki, aby płatki mogły się szczelnie zamykać
- Łatanie dziur lub rozdarć w zastawce
- Walwuloplastyka balonowa (poszerzenie zwężonej zastawki za pomocą balonu)
Walwuloplastyka balonowa jest zabiegiem przezskórnym, w którym cewnik z balonem na końcówce wprowadza się przez naczynie krwionośne, najczęściej w pachwinie, do zastawki aorty. Balon zostaje napompowany, co powoduje rozszerzenie zwężonej zastawki. Zabieg ten jest stosowany głównie u niemowląt i dzieci ze stenozą zastawki aorty, a także u dorosłych jako tymczasowe rozwiązanie przed wymianą zastawki lub jako leczenie paliatywne u pacjentów, którzy nie kwalifikują się do operacji.131516
Operacyjna wymiana zastawki aorty (SAVR)
Tradycyjna wymiana zastawki aorty (SAVR – Surgical Aortic Valve Replacement) jest wykonywana na otwartym sercu i polega na usunięciu uszkodzonej zastawki i zastąpieniu jej protezą. W zależności od stanu pacjenta, możliwe są różne techniki operacyjne:121718
Dostępne są dwa główne typy protez zastawkowych:121719
- Zastawki mechaniczne – wykonane z trwałych materiałów, takich jak węgiel czy tytan. Są bardzo wytrzymałe i mogą służyć przez całe życie pacjenta, jednak wymagają stałego przyjmowania leków przeciwzakrzepowych.
- Zastawki biologiczne – wykonane z tkanek zwierzęcych (świńskich lub bydlęcych) lub ludzkich. Nie wymagają długotrwałej antykoagulacji, ale są mniej trwałe i mogą wymagać wymiany po 10-15 latach.
Chirurgiczna wymiana zastawki aorty może być przeprowadzona jako tradycyjna operacja na otwartym sercu lub jako zabieg minimalnie inwazyjny z mniejszym nacięciem. Wybór techniki zależy od stanu pacjenta, anatomii serca oraz doświadczenia zespołu chirurgicznego.2021
Przezcewnikowa wymiana zastawki aorty (TAVR/TAVI)
Przezcewnikowa wymiana zastawki aorty (TAVR – Transcatheter Aortic Valve Replacement, nazywana również TAVI – Transcatheter Aortic Valve Implantation) jest minimalnie inwazyjną alternatywą dla tradycyjnej operacji wymiany zastawki aorty. Zabieg TAVR polega na wprowadzeniu składanej zastawki biologicznej przez cewnik, najczęściej przez tętnicę udową, do miejsca uszkodzonej zastawki aorty.20222
- Cewnik z zastawką zostaje wprowadzony przez naczynie krwionośne, najczęściej w pachwinie
- Pod kontrolą obrazowania, cewnik jest prowadzony do serca i pozycjonowany w miejscu chorej zastawki aorty
- Zastawka jest uwalniana i rozprężana, przejmując funkcję uszkodzonej zastawki
- Niektóre zastawki są rozprężane za pomocą balonu, a inne są samoczynnie rozprężalne
TAVR początkowo była dostępna tylko dla pacjentów wysokiego ryzyka chirurgicznego, którzy nie kwalifikowali się do tradycyjnej operacji. Obecnie, w wyniku licznych badań klinicznych potwierdzających skuteczność i bezpieczeństwo tej metody, TAVR jest stosowana również u pacjentów o niższym ryzyku chirurgicznym.222627
Główne zalety TAVR w porównaniu z SAVR obejmują:222728
- Krótszy czas zabiegu (około 1 godziny w porównaniu do 4 godzin przy operacji na otwartym sercu)
- Szybszy powrót do zdrowia i krótszy pobyt w szpitalu (większość pacjentów wraca do domu następnego dnia)
- Mniejszy ból pooperacyjny i mniejsza trauma
- Brak konieczności stosowania krążenia pozaustrojowego
- Możliwość wykonania zabiegu bez znieczulenia ogólnego u wybranych pacjentów
Specjalistyczne procedury naprawy i wymiany zastawki aorty
W niektórych ośrodkach dostępne są specjalistyczne procedury naprawy i wymiany zastawki aorty, takie jak:142930
Procedura Rossa – zabieg, w którym uszkodzona zastawka aorty jest zastępowana własną zastawką płucną pacjenta, a na miejsce zastawki płucnej wszczepiana jest zastawka biologiczna. Ta technika jest szczególnie korzystna dla młodszych pacjentów, ponieważ przeszczepiona zastawka płucna może rosnąć wraz z dzieckiem i nie wymaga długotrwałej antykoagulacji.2931
Operacja oszczędzająca zastawkę aorty (valve-sparing) – procedura stosowana w przypadku tętniaka lub rozwarstwienia opuszki aorty, gdy zastawka aorty jest zdrowa. Polega na wymianie części aorty z zachowaniem własnej zastawki pacjenta, co eliminuje konieczność stosowania leków przeciwzakrzepowych.3233
Powiększenie korzenia aorty – procedura opracowana w centrum sercowo-naczyniowym Frankel, polegająca na powiększeniu korzenia aorty i wszczepieniu protezy zastawki o 3-4 rozmiary większej. Większa zastawka zapewnia lepszy przepływ krwi, poprawę jakości życia i długoterminowe przeżycie.14
Wybór optymalnej metody leczenia
Wybór najlepszej metody leczenia choroby zastawki aorty powinien być dokonany indywidualnie dla każdego pacjenta, uwzględniając:12434
- Rodzaj i zaawansowanie choroby zastawki aorty (stenoza vs. niedomykalność)
- Wiek pacjenta i przewidywaną długość życia
- Choroby współistniejące i ogólny stan zdrowia
- Ryzyko operacyjne
- Preferencje pacjenta dotyczące jakości życia i długoterminowych wymagań terapeutycznych
Decyzja powinna być podejmowana w ramach wielodyscyplinarnego zespołu (Heart Team), składającego się z kardiologów, kardiochirurgów, kardiologów interwencyjnych i innych specjalistów, we współpracy z pacjentem.3536
Wskazania do interwencji zastawkowej
Według wytycznych American Heart Association, interwencja w chorobie zastawki aorty jest zalecana w następujących przypadkach:43738
W przypadku stenozy aortalnej:
- U pacjentów objawowych z ciężką stenozą aortalną, niezależnie od funkcji skurczowej lewej komory
- U pacjentów bezobjawowych z ciężką stenozą aortalną i dysfunkcją skurczową lewej komory (frakcja wyrzutowa <50%)
- U pacjentów z ciężką stenozą aortalną poddawanych operacji kardiochirurgicznej z innych wskazań
W przypadku niedomykalności aortalnej:
- U pacjentów objawowych z ciężką niedomykalnością aortalną, niezależnie od funkcji skurczowej lewej komory
- U pacjentów bezobjawowych z przewlekłą ciężką niedomykalnością aortalną i dysfunkcją skurczową lewej komory (frakcja wyrzutowa <50%)
- U pacjentów z ciężką niedomykalnością aortalną poddawanych operacji kardiochirurgicznej z innych wskazań
Porównanie metod leczenia zabiegowego
Wybór między SAVR a TAVR powinien być dokonany na podstawie indywidualnej oceny korzyści i ryzyka. Zalecenia mogą się różnić w zależności od ośrodka oraz najnowszych badań klinicznych.61627
| Parametr | SAVR (Chirurgiczna wymiana zastawki) | TAVR (Przezcewnikowa wymiana zastawki) |
|---|---|---|
| Inwazyjność | Operacja na otwartym sercu lub minimalnie inwazyjna | Procedura przezskórna, małe nacięcie |
| Znieczulenie | Znieczulenie ogólne | Możliwe bez znieczulenia ogólnego |
| Czas zabiegu | Około 4 godziny | Około 1 godziny |
| Pobyt w szpitalu | 5-7 dni | 1-2 dni |
| Czas rekonwalescencji | 4-8 tygodni | Około 1 tygodnia |
| Trwałość zastawki | Dłuższa (szczególnie zastawki mechaniczne) | Krótsza (tylko zastawki biologiczne) |
| Zalecana dla | Młodsi pacjenci z niskim ryzykiem chirurgicznym | Starsi pacjenci, wysokie ryzyko chirurgiczne |
| Główne ryzyko | Powikłania związane z operacją | Przeciek okołozastawkowy, udar, uszkodzenie naczyń |
Postępowanie po interwencji zastawkowej
Pacjenci po operacji lub zabiegu na zastawce aorty wymagają długoterminowej opieki medycznej i monitorowania.173439
Farmakoterapia po zabiegu
Po wymianie zastawki aorty pacjenci często wymagają długoterminowej farmakoterapii:394041
- Leki przeciwzakrzepowe – pacjenci z zastawkami mechanicznymi wymagają dożywotniej antykoagulacji (warfaryna) w celu zapobiegania zakrzepom. Docelowa wartość INR zależy od typu zastawki i obecności dodatkowych czynników ryzyka zakrzepowo-zatorowego.
- Leki przeciwpłytkowe – po TAVR zalecane jest stosowanie kwasu acetylosalicylowego (aspiryny) bezterminowo oraz klopidogrelu przez pierwsze 3-6 miesięcy.
- Leki kontrolujące ciśnienie krwi – mogą być potrzebne do optymalizacji obciążenia hemodynamicznego po zabiegu.
- Antybiotyki – profilaktyka infekcyjnego zapalenia wsierdzia przed procedurami stomatologicznymi i innymi zabiegami niosącymi ryzyko bakteriemii.
Rehabilitacja kardiologiczna
Rehabilitacja kardiologiczna jest ważnym elementem opieki po zabiegu na zastawce aorty. Obejmuje ona:1742
- Kontrolowane ćwiczenia fizyczne
- Edukację pacjenta na temat choroby i zdrowego stylu życia
- Wsparcie psychologiczne
- Porady dotyczące diety i odżywiania
- Wsparcie w rzucaniu palenia
Długoterminowe monitorowanie
Pacjenci po operacji zastawki aorty wymagają regularnych kontroli kardiologicznych, które obejmują:84344
- Okresowe badania echokardiograficzne w celu oceny funkcji zastawki
- Monitorowanie poziomu INR u pacjentów z zastawkami mechanicznymi
- Ocenę potencjalnych powikłań, takich jak infekcyjne zapalenie wsierdzia, dysfunkcja zastawki lub pęknięcie
- W przypadku zastawek biologicznych – śledzenie oznak degeneracji zastawki, która może wystąpić po 10-15 latach
Wyniki leczenia i rokowanie
Skuteczne leczenie choroby zastawki aorty znacząco poprawia rokowanie i jakość życia pacjentów. Bez leczenia, ciężka choroba zastawki aorty może prowadzić do niewydolności serca i zgonu.453846
Wyniki leczenia zabiegowego są zazwyczaj bardzo dobre:23443
- Wskaźniki śmiertelności operacyjnej są niskie w doświadczonych ośrodkach
- Większość pacjentów odczuwa znaczną poprawę objawów po zabiegu
- Poprawa jakości życia jest obserwowana u przytłaczającej większości pacjentów
- Długoterminowe przeżycie po skutecznej wymianie zastawki aorty zbliża się do przewidywanego dla populacji ogólnej w odpowiednim wieku
Czynniki wpływające na rokowanie obejmują:471148
- Wiek i ogólny stan zdrowia pacjenta
- Stadium choroby w momencie interwencji
- Funkcja lewej komory przed zabiegiem
- Współistniejące choroby sercowo-naczyniowe
- Typ wszczepionej zastawki
- Doświadczenie ośrodka wykonującego zabieg
Wczesna interwencja, zanim dojdzie do nieodwracalnego uszkodzenia serca, oferuje najlepsze szanse na pozytywne wyniki leczenia i długoterminowe przeżycie.4950
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Materiały źródłowe
- #1 Aortic valve disease – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/aortic-valve-disease/diagnosis-treatment/drc-20355122
Treatment for aortic valve disease depends on: The severity (stage) of aortic valve disease. Whether the disease is causing symptoms. Whether the condition is getting worse. […] Treatment may include regular health checkups, lifestyle changes, medicines, or surgery or other procedures. If you have aortic valve disease, consider being evaluated and treated at a medical center with a multidisciplinary team of heart doctors called cardiologists and other care professionals trained and experienced in evaluating and treating heart valve disease. […] Eventually, surgery or a catheter procedure may be needed to repair or replace the diseased aortic valve. Some people with aortic valve disease need surgery even if it’s not severe or when it’s not causing symptoms. […] Surgery to repair or replace an aortic valve is often done with open-heart surgery. Sometimes, the valve can be replaced during minimally invasive heart surgery, which uses smaller incisions than those needed for open-heart surgery, or with a catheter-based procedure.
- #2 Aortic Valve Disease > Fact Sheets > Yale Medicinehttps://www.yalemedicine.org/conditions/aortic-valve-disease
Treatment involves surgery, minimally invasive procedures, and medication. […] Fortunately, effective treatments are available that can help alleviate symptoms and even restore normal blood flow. […] While medications and avoidance of physically demanding activities can help to control symptoms, they cannot cure aortic valve disease. The disease is caused by changes to the physical structure of the valve (it becomes narrowed or can no longer open or close completely). Thus, the main treatments for aortic valve disease are repair or replacement of the valve. […] Techniques for repairing or replacing the aortic valve include: Surgery. Aortic valve repair and replacement has been done via open-heart surgery for decades. It’s a well-established approach, and has proven to be safe. […] Balloon valvuloplasty. This is a repair procedure in which a doctor inserts a catheter with a balloon at its tip into a blood vessel, then maneuvers it to the heart and aortic valve. […] Transcatheter aortic valve replacement (TAVR). In this minimally invasive procedure, a doctor performs a balloon valvuloplasty to stretch out the old valve. […] Aortic valve surgery is safe and has proven long-term benefits. It can help alleviate patients’ symptoms and prolong their lives.
- #3 Aortic Valve Disease | Frankel Cardiovascular Center | Michigan Medicinehttps://www.umcvc.org/conditions-treatments/aortic-valve-disease
Aortic valve diseases can threaten your health and impact your quality of life. Our heart and vascular specialists at the University of Michigan Health Frankel Cardiovascular Center are skilled in diagnosing and treating diseases of the aortic valve. […] We use innovative techniques and a unique team-based approach to help you feel better as quickly as possible. […] Our surgeons are among the top in the nation. They are continually developing new treatments and refining existing ones to improve patient outcomes. […] As one of the nations largest aortic valve programs, we participate in clinical trials for medical device companies. This gives you access to treatments and devices that may not be available elsewhere. […] Our team meets weekly to review your case, evaluate your symptoms and identify treatment options. We then work with you to develop a treatment plan that is best for your condition and personal needs.
- #4 Aortic Valve Disease – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK542205/
Aortic valve replacement is the most essential treatment modality. It is generally indicated in patients with symptomatic aortic valve disease or severe disease, as the American Heart Association guidelines indicate. […] Valve replacement for aortic stenosis is recommended for asymptomatic patients (evidenced by history or stress testing) with a high-gradient disease or asymptomatic patients with severe aortic stenosis (C2) and a left ventricular ejection fraction less than 50%. […] Valve replacement for the treatment of aortic regurgitation is indicated for symptomatic patients with severe AR regardless of LV systolic function (D), asymptomatic patients with chronic severe AR and evidence of LV systolic dysfunction (EF less than 50%; ie, C2), and patients with severe AR (C or D) while undergoing cardiac surgery for any other indication.
- #5 Aortic valve stenosis – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/aortic-stenosis/diagnosis-treatment/drc-20353145
Treatment for aortic valve stenosis depends on the symptoms and how severe the condition is. Aortic valve stenosis ranges from mild to severe. […] If you have no symptoms or just mild ones, you may only need regular health checkups. Some people need medicines to treat valve disease symptoms or reduce the risk of complications. […] Other treatments for aortic valve disease may include: Heart-healthy lifestyle changes. Eat healthy, get regular exercise and stay active, and do not smoke. Medicines to treat symptoms or reduce the risk of complications. Surgery to fix or replace the valve. […] Some people with aortic valve stenosis may need medicines to treat symptoms or reduce the risk of complications. For example, medicines may be used to: Lower blood pressure. Prevent irregular heartbeats. Remove excess fluid from the body to reduce the strain on the heart.
- #6 Aortic Stenosis: Diagnosis and Treatment | AAFPhttps://www.aafp.org/pubs/afp/issues/2016/0301/p371.html
Watchful waiting is recommended for most asymptomatic patients with aortic stenosis, including those with severe disease. […] Transcatheter aortic valve replacement is recommended for patients who have an indication for valve replacement but are at prohibitive surgical risk. […] Surgical aortic valve replacement is the standard of care in patients with low or intermediate surgical risk.
- #7 Heart Valve Disease Treatment Without Surgery: The Optionshttps://www.healthline.com/health/heart-valve-disease-treatment-without-surgery
Heart valve disease doesnt always require surgery. Nonsurgical treatments like medications, lifestyle changes, or minimally invasive procedures are sufficient for some people. […] A doctor may recommend nonsurgical options if your heart valve disease is mild or to help minimize your risk of complications while you wait for surgery. […] Medications can help reduce your symptoms, prevent complications, and take the stress off your heart. […] Lifestyle changes alone might be enough to treat minor heart valve disease or help maximize your heart health until you can receive surgical treatment. […] Surgeons can use nonsurgical procedures to treat heart valve disease by repairing your valve from within your bloodstream. These are called percutaneous valve procedures. […] Your life expectancy depends on the type and extent of your heart valve disease. Minor problems might never cause complications or shorten your life span, even without surgery. But severe disease might lead to fatal complications without treatment.
- #8 Heart Valve Diseases – Treatment | NHLBI, NIHhttps://www.nhlbi.nih.gov/health/heart-valve-diseases/treatment
Your healthcare provider may recommend healthy lifestyle changes or medicine first to treat symptoms, which may delay problems. […] Eventually, you may need to have your faulty heart valve repaired or replaced. After repair or replacement, you’ll still need certain medicines and regular checkups with your doctor. […] Your doctor may prescribe medicines to relieve the symptoms of your heart valve disease, prevent it from getting worse, or treat other heart problems that can affect your heart valves. […] Your doctor may recommend heart valve repair if you have new symptoms of heart valve disease or your current symptoms get worse. […] Heart valve repair can improve symptoms, but sometimes problems return. […] Sometimes faulty or diseased heart valves cannot be repaired and must be replaced.
- #9 Heart Valve Disease: Symptoms & Treatmenthttps://my.clevelandclinic.org/health/diseases/17639-what-you-need-to-know-heart-valve-disease
Although medicines cant cure heart valve disease, they and a healthy lifestyle can help with symptoms and decrease your chance of having a stroke or cardiac arrest. You may be able to stop taking some medications after valve surgery, but you may need to take other medicines for the rest of your life. […] Heart valve disease is a problem with the opening or closing of your leaflets, and you may need surgery to repair or replace your valve. Some infants who have congenital (present at birth) valve issues need surgery during childhood. […] Heart valve repair allows your surgeon to fix your faulty valve, often without the use of artificial parts. In some cases, like a narrow mitral valve, your provider may use a balloon on a catheter (valvuloplasty) to widen your valve. They may perform an annuloplasty to fix or reinforce the ring around your valve so it closes better.
- #10 Aortic Valve Disease | Duke Healthhttps://www.dukehealth.org/treatments/heart/aortic-valve-disease
Aortic valve diseases, including aortic valve stenosis (a narrowed valve opening) and aortic valve regurgitation (a leaking valve), require evaluation and management by a cardiologist or cardiac surgeon. More serious conditions may require surgery to repair or replace the aortic valve. […] Our cardiologists and heart surgeons use a full range of therapies to treat aortic valve disease. When surgery is needed, our skilled heart surgeons repair or replace diseased aortic valves, often with minimally invasive techniques. […] Medications may be prescribed to reduce and prevent aortic valve disease symptoms and complications. These may include ACE inhibitors or beta-blockers to lower blood pressure, antiarrhythmics to help maintain a regular heart rhythm, anticoagulants to prevent blood clots, and diuretics that can help reduce fluid retention.
- #11 Medical management of symptomatic aortic stenosis – UpToDatehttps://www.uptodate.com/contents/medical-management-of-symptomatic-aortic-stenosis
Aortic valve replacement (AVR, including surgical aortic valve replacement and transcatheter aortic valve implantation [TAVI]) is the mainstay of treatment of symptomatic aortic stenosis (AS). AVR offers substantial improvements in symptoms and life expectancy. Medical therapy may not prolong life in patients with AS and has limited utility in treating symptoms. […] In patients who are awaiting AVR, medical therapy to optimize hemodynamics in the preoperative setting may be needed. When severe symptoms are present, it may be prudent to admit the patient to the hospital and perform AVR urgently, as there is a high risk of cardiac death once severe symptoms are present. […] Longer-term palliative medical management of symptomatic AS is appropriate for patients who are not candidates for aortic valve intervention due to coexisting medical conditions and in patients who decline aortic valve intervention. TAVI enables AVR in many patients with prohibitive or high operative risk for surgical AVR. However, TAVI may not be feasible in some patients due to anatomic factors or may not be appropriate in patients with a limited life expectancy due to other comorbidities or extreme frailty.
- #12 Aortic valve disease – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/aortic-valve-disease/diagnosis-treatment/drc-20355122
During aortic valve repair, the surgeon may do one or all of the following: Separate valve flaps that have fused. Add support to the base of the valve. Reshape or remove excess valve tissue so that the cusps can close tightly. Patch holes or tears in a valve. […] In a mechanical valve replacement, an artificial heart valve made of strong material replaces the damaged valve. […] In a biological valve replacement, a valve made from cow, pig or human heart tissue replaces the damaged heart valve. […] Transcatheter aortic valve replacement (TAVR) is a type of heart valve surgery. It’s done to replace a narrowed aortic valve, a condition called aortic valve stenosis. A doctor inserts a flexible tube called a catheter into a blood vessel and guides it into the heart. A replacement valve made of cow or pig tissue goes through the tube to the specific area in the heart. A balloon on the catheter tip inflates to press the new valve into place. Some valves are self-expanding.
- #13 Aortic Valve Disease, Osseo – Mayo Clinic Health Systemhttps://www.mayoclinichealthsystem.org/locations/osseo/services-and-treatments/cardiology/diseases/aortic
Aortic valve disease is a condition where the valve between the main pumping chamber of your heart and the main artery to your body, the aorta, doesn’t work properly. Aortic valve disease may be a congenital condition or it can result from other causes. […] Your treatment depends on the type and severity of your aortic valve disease. In some cases, you may need surgery to repair or replace the aortic valve. […] To repair an aortic valve, surgeons may conduct several types of repair, including separating valve flaps that have fused, removing excess valve tissue so that the valve flaps can close tightly or patching holes in a valve. […] Doctors may conduct a procedure using a long, thin tube, or catheter, to open up a valve with a narrowed opening. This is called aortic valve stenosis. In this procedure, which is called balloon valvuloplasty, a doctor inserts a catheter with a balloon on the tip into an artery in your groin and guides it to the aortic valve. A doctor then inflates the balloon, which expands the opening of the valve. The balloon is then deflated, and the catheter and balloon are removed.
- #14 Aortic Disease Treatments and Procedures | University of Michigan Healthhttps://www.uofmhealth.org/conditions-treatments/aortic-disease-treatments-and-procedures
Open aortic valve procedures require direct access to the heart. Procedures available to patients at the Frankel Cardiovascular Center include: […] Aortic valve repair or replacement: If you have a leaking valve, repair allows you to keep your valve, which may improve long-term outcomes. If repair is not possible, the valve can be replaced with a mechanical or tissue valve. […] The Ross procedure is most often performed on younger patients. […] This procedure developed at the Frankel Cardiovascular Center offers excellent outcomes for people who need a new aortic valve. The cardiac surgeon enlarges the aortic root and inserts a prosthetic valve that is three to four valve sizes larger. The large valve results in improved blood flow, quality of life and long-term survival.
- #15 Aortic valve stenosis – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/aortic-stenosis/diagnosis-treatment/drc-20353145
You may eventually need a surgery to repair or replace the narrowed aortic valve, even if you don’t have symptoms. Aortic valve surgery may be done at the same time as other types of heart surgery. […] Surgery to repair or replace an aortic valve is usually done through a cut in the chest. Less invasive approaches may be available. Ask your healthcare professional which type of aortic valve treatment is best for you. […] Surgery and procedures for aortic valve stenosis include: Balloon valvuloplasty. This treatment helps open a narrowed valve. It may be done in infants and children with aortic valve stenosis. In adults, the aortic valve tends to narrow again after the treatment. So it’s usually done only if an adult is too sick for surgery or if an adult is waiting for a valve replacement.
- #16 Aortic Valve Disease – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK542205/
Patients whose life expectancy after the replacement is less than 1 year or whose quality of life is not expected to improve would not be candidates for valve replacement. However, if life expectancy is greater than 1 year, and predictions include improvement in the quality of life, there are 2 methods for aortic valve replacement: surgical or transcatheter. […] Transcatheter aortic valve replacement is only indicated for aortic stenosis, not aortic regurgitation. Electing 1 method over the other is determined by evaluating the morbidity and mortality risk of surgical valve replacement, often utilizing the Society of Thoracic Surgeons Predicted Risk of Mortality (STS-PROM). If the risk of serious complications or death is greater than 50%, transcatheter aortic valve replacement (TAVR) is the preferred option. If the surgical risk is less than 50%, the consensus has been that SAVR is the preferred method. However, several studies now show no difference in morbidity and mortality 1-year post-op between SAVR and TAVR and that TAVR is safe to use in any patient regardless of the risk level. […] This procedure involves balloon inflation in the valve orifice to widen the valve, used only as a temporary bridge to valve replacement for hemodynamically unstable patients or for palliative/symptomatic relief in patients who are not surgical candidates.
- #17 Heart Valve Disease: Symptoms & Treatmenthttps://my.clevelandclinic.org/health/diseases/17639-what-you-need-to-know-heart-valve-disease
Replacing your heart valve involves removing your old valve and sewing a new valve to the ring-shaped part of your old one. The new valve could be mechanical or biological (made with tissue from a human, cow or pig). These replacement valves can provide function when repair cant. But depending on the type of valve you get, you may have to take certain medications to prevent blood clots or get a new valve again in 10 or 15 years. […] Depending on the type of valve problem and your other medical conditions, you may be able to have minimally invasive valve repair or replacement. […] Older people and those whose health isnt good to begin with have a higher risk of complications from valve replacement surgery. […] You may be in the hospital for about five to seven days after heart valve surgery. After that, it can take about four to eight weeks to recover. Your provider may recommend cardiac rehab, a carefully monitored program to assist with your recovery.
- #18 Heart Valve Diseases – Treatment | NHLBI, NIHhttps://www.nhlbi.nih.gov/health/heart-valve-diseases/treatment
Your surgeon will replace the faulty or diseased valve with either a mechanical or a biological heart valve. […] Valves can be replaced during open-heart surgery or with a minimally invasive procedure using a catheter a thin tube threaded through a blood vessel to the heart. […] Your doctor will discuss which heart treatment is best for your circumstances. […] The risks of heart valve replacement include stroke, blood clots, damage and bleeding where the catheters were inserted, and injury to the kidneys or the heart. Sometimes the new valve leaks because it does not fit well. […] NHLBI-funded scientists have developed new ways to make transcatheter aortic valve replacement (TAVR) surgery safer for high-risk patients.
- #19 Options for Heart Valve Replacement | American Heart Associationhttps://www.heart.org/en/health-topics/heart-valve-problems-and-disease/understanding-your-heart-valve-treatment-options/options-for-heart-valve-replacement
The aortic valve is the most commonly replaced valve. […] The most common surgical procedure for aortic stenosis, or narrowing of the aortic valve, is aortic valve replacement. […] Aortic regurgitation, sometimes referred to as aortic insufficiency, is another common valve problem that may require valve replacement. […] Surgical options for valve replacement include: Mechanical valve â a long-lasting valve made of durable materials, Tissue valve â may include human or animal donor tissue, Ross Procedure â âBorrowingâ your healthy valve and moving it into the position of the damaged valve aortic valve and replacing the âborrowedâ valve with a new valve, TAVI/TAVR procedure â Transcatheter aortic valve implantation/transcatheter aortic valve replacement, Less invasive surgery options. […] The procedure chosen will depend on the valve that needs replacement, the severity of symptoms and the risk of surgery. Some procedures may require long-term medication to guard against blood clots. […] Age is not the only factor in making a decision on treatment. It is critical to talk to your care team to weigh the risks and benefits of each approach and take into account your values and preferences.
- #20 Aortic valve disease – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/aortic-valve-disease/diagnosis-treatment/drc-20355122
Aortic valve replacement typically requires open-heart surgery. Sometimes, surgeons can use a minimally invasive procedure called transcatheter aortic valve replacement (TAVR) to replace a narrowed aortic valve with a biological tissue valve. TAVR uses smaller incisions than those used in open-heart surgery. TAVR may be an option for people at increased risk of heart valve surgery complications.
- #21 Aortic Valve Disease | Northwestern Medicinehttps://www.nm.org/conditions-and-care-areas/heart-and-vascular/conditions-and-treatments/aortic-valve-disease-old/treatments
Northwestern Medicine offers many approaches to aortic valve surgery. The choice of incision depends on: How much work is needed to repair or replace the valve, Whether any other procedures are needed to fix other heart problems, Whether you have had any other chest surgery, Other factors. […] Our priority is to give you the safest possible operation, with the best possible recovery.
- #22 Aortic Valve Disease | UNC Heart Valve Clinichttps://www.med.unc.edu/medicine/cardiology/uncheartvalve/diseases-and-treatments/aortic-valve-disease/
Aortic valve stenosis occurs when the opening of the aortic valve becomes narrowed and the valve no longer opens fully with each heartbeat. […] Unfortunately, at least 1/3 of patients with aortic valve stenosis today are not receiving valve replacement, which is the only treatment that is effective for this condition. […] Transcatheter aortic valve replacement (TAVR) is an alternate treatment option to conventional open heart surgery, and TAVR has shown to have equal, and sometimes better outcomes than traditional surgery. […] With TAVR, physicians now have the ability to provide aortic valve replacement via minimally-invasive approaches, including percutaneous procedures (intervention without an incision), which provide outcomes that are as good, or sometimes better than, surgical valve replacement.
- #23 Aortic Valve Disease, Osseo – Mayo Clinic Health Systemhttps://www.mayoclinichealthsystem.org/locations/osseo/services-and-treatments/cardiology/diseases/aortic
Aortic valve replacement is often needed to treat aortic valve disease. In aortic valve replacement, your surgeon removes the damaged valve and replaces it with a mechanical valve, or a valve made from cow, pig or human heart tissue. The latter is called a biological or tissue valve. Another type of biological tissue valve replacement that uses your own pulmonary valve is sometimes possible. […] Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure to replace a narrowed aortic valve that fails to open properly. This is called aortic valve stenosis. Transcatheter aortic valve replacement is sometimes called transcatheter aortic valve implantation (TAVI). […] TAVR is usually reserved for people who can’t undergo open-heart surgery or surgery presents too many risks. TAVR can relieve the signs and symptoms of aortic valve stenosis, and may improve survival in people who can’t undergo surgery or have a high risk of surgical complications.
- #24 Aortic Disease Treatments and Procedures | University of Michigan Healthhttps://www.uofmhealth.org/conditions-treatments/aortic-disease-treatments-and-procedures
Our Comprehensive Aortic Program at the Frankel Cardiovascular Center offers a wide range of treatment options for aortic disease. […] Aortic valves can be replaced or repaired. In patients who have aortic valve stenosis, replacement is usually the only option. If the valve is leaking, it can be repaired or replaced. […] In general, surgeons prefer aortic valve repair over replacement, especially in younger patients. Your surgeon will discuss your options and recommend the optimal procedure and valve type for you. […] At the Frankel Cardiovascular Center, our surgeons perform all types of aortic valve repair and replacement, including: […] TAVR is a minimally invasive procedure for patients with aortic stenosis. Our surgeons insert a tissue valve inside the diseased valve. The replacement valve expands in place, where it immediately takes over valve function.
- #25 Aortic Valve Treatment – Heart | NewYork-Presbyterianhttps://www.nyp.org/heart/heart-valves/aortic-valve-treatment
Aortic stenosis is a narrowing of the aortic valve, which lies between the left ventricle and the aorta. NewYork-Presbyterian has more experience with transcatheter aortic valve replacement (TAVR) than any other center in the country. During this procedure, an interventional cardiologist implants a device through a catheter (long, flexible tube) threaded through a blood vessel in your leg and guided to your heart. Clinical trials, including those co-led by our physician-scientists, have shown TAVR to be a safe and effective minimally invasive option which results in shorter hospital stays and a lower risk of complications for patients of all ages and risk levels. This treatment was once primarily indicated for patients considered high-risk for traditional surgery, but it is now also used in patients at low risk who are experiencing symptoms.
- #26 Aortic Valve Treatments | Division of Cardiologyhttps://www.columbiacardiology.org/patient-care/columbia-structural-heart-and-valve-center/conditions-and-treatments/aortic-valve-treatments
This life-saving device originally provided a treatment option for patients who were too sick or too old to undergo a surgical replacement. It is now FDA approved for all patients independent of surgical risk. […] TAVR is now an option for the majority of patients with aortic stenosis, offering a much shorter recovery time and lower procedural risk than open heart surgery. […] During open heart surgery using general anesthesia, a mechanical or biological tissue valve is implanted to replace the damaged aortic valve. This type of treatment is highly effective, but is associated with a longer recovery time. […] Some aortic valve conditions can be repaired as an alternative to replacement or as a bridge to replacement. […] In general, transcatheter procedures require less recovery time than surgical treatments. The majority of patients go home the next day after the procedure in good health, with no restrictions after one week. […] Patients may also take medications after treatment to control blood pressure or reduce the risk of blood clots.
- #27 Severe Aortic Stenosis Treatment Options | Heart Valve Failure Patienthttps://treatheartvalvefailure.com/about-treatment/treatment-options
Heart valve failure may sound scary, but it’s treatable, and you should know your options. TAVR (transcatheter aortic valve replacement) and SAVR (surgical aortic valve replacement), also called open heart surgery, are both ways to replace your heart valve. They reduce your risk of death from heart valve failure and provide relief from your symptoms. They each have their own key differences. […] TAVR does not involve opening the chest. The average TAVR procedure takes about 1 hour. Open heart surgery, by comparison, lasts about 4 hours. Most TAVR patients return home the next day and have a short recovery time, getting them back to everyday activities quickly. TAVR may also be used for patients at high risk for surgery. […] The PARTNER 3 Trial, SAPIEN 3 TAVR proven superior to surgery on the primary endpoint of all-cause death, all stroke, and re-hospitalization (valve-related or procedure-related and including heart failure) at one year, and multiple pre-specified secondary endpoints in low risk patients.
- #28 Aortic Valve Treatments | Division of Cardiologyhttps://www.columbiacardiology.org/patient-care/columbia-structural-heart-and-valve-center/patient-care/conditions-and-treatments/aortic-valve-treatments
This life-saving device originally provided a treatment option for patients who were too sick or too old to undergo a surgical replacement. It is now FDA approved for all patients independent of surgical risk. […] TAVR is now an option for the majority of patients with aortic stenosis, offering a much shorter recovery time and lower procedural risk than open heart surgery. […] During open heart surgery using general anesthesia, a mechanical or biological tissue valve is implanted to replace the damaged aortic valve. This type of treatment is highly effective, but is associated with a longer recovery time. […] Some aortic valve conditions can be repaired as an alternative to replacement or as a bridge to replacement. […] Recovery from aortic valve treatment will vary based on several factors, including the type of treatment, the severity of disease, additional heart conditions, previous surgeries, age, and overall health.
- #29 Aortic Valve Disease | Frankel Cardiovascular Center | Michigan Medicinehttps://www.umcvc.org/conditions-treatments/aortic-valve-disease
During open surgery, the aortic valve can be replaced or repaired. […] Patients with stenosis typically require valve replacement. […] Leaky valves can often be repaired or replaced. […] Because replacement valves have a limited lifespan, surgeons prefer to repair a diseased aortic valve if possible, especially in younger patients. […] Our surgeons have developed a reputation as leaders in aortic valve open surgery. […] This procedure is used when an aortic aneurysm or dissection occurs near the aortic root, but the valve is healthy. […] The surgeon replaces the diseased aortic valve with the pulmonary valve. […] The Ross procedure is often preferred for younger patients because the relocated aortic valve can grow with the child. […] This procedure was developed at the Frankel Cardiovascular Center and is recognized globally as game-changing for patients who need a new aortic valve but have a small aortic root.
- #30 Evolving treatment options for valve and aortic disease with bicuspid aortic valvehttps://atm.amegroups.org/article/view/14868/html
Treatment decisions for patients with bicuspid aortic valves (BAVs) are unique for two principal reasons: (I) aortopathy with dilation of the proximal aorta is seen about 50% of cases, and frequently requires a combined repair; (II) patients are significantly younger than those undergoing treatment for acquired aortic valve disease, making the durability and lifestyle implications of treatment choices increasingly important. The traditional treatment for valve and aortic disease with BAV is composite or separate replacement of the valve and ascending aorta. While mechanical aortic valves are more durable, they require life-long anticoagulation. Bioprosthetic valves may be an even less attractive option for younger patients as primary valve failure has been reported in 26% of cases at 15 years. In this context, an alternative treatment approach with repair rather than replacement of the valve and aortic root, as proposed by Cosgrove et al. and later refined by Schfers et al., is very appealing.
- #31 Surgical treatment of aortic valve disease | Nature Reviews Cardiologyhttps://www.nature.com/articles/nrcardio.2013.72
Young adults with aortic stenosis, particularly women during childbearing years, can be treated with the Ross procedure. […] Finally, poor candidates for surgery who have aortic stenosis can now be treated with catheter-based aortic valve implantation but, in this article, the current status of aortic valve surgery is reviewed.
- #32 Aortic Valve Regurgitation: Treatment & Diagnosis | Mass General Brighamhttps://www.massgeneralbrigham.org/en/patient-care/services-and-specialties/heart/conditions/aortic-valve-regurgitation/treatment
TAVR is a minimally invasive surgery used to replace the aortic valve. A prosthetic valve is inserted through a catheter, typically placed via an artery in the groin. While TAVR is currently used primarily for patients with severe aortic stenosis, research is ongoing to explore its potential use for patients with aortic regurgitation in the future. […] This surgery replaces the aortic root while keeping the valve intact. Retaining the aortic valve eliminates the need for lifelong blood-thinning medications often required with valve replacement surgeries.
- #33 Aortic Valve Conditions and Treatmenthttps://www.froedtert.com/heart-valve-disease/aortic-valve
Aortic valve stenosis can, in some cases, be treated with the minimally invasive transcatheter aortic valve replacement (TAVR) procedure. […] We provide the widest range of options for aortic valve treatment. Whether your heart valve is repaired or replaced depends on many factors and both approaches can be highly successful. […] TAVR offers patients with aortic valve disease a minimally invasive alternative to open heart surgery. […] This transcatheter procedure uses a balloon to open or widen the problem valve to restore normal blood flow in patients. […] Underlying medical conditions, multiple heart problems and other factors may mean you will do better with a traditional, open procedure for aortic valve repair or replacement. […] Valve-sparing aortic root replacement aims to repair an aortic aneurysm or dissection preserving the patients own aortic valve instead of implanting an artificial valve.
- #34 Understanding Your Heart Valve Treatment Options | American Heart Associationhttps://www.heart.org/en/health-topics/heart-valve-problems-and-disease/understanding-your-heart-valve-treatment-options
Most valve conditions canât be treated with medication alone. However, sometimes the problem isnât severe enough to require repair or valve replacement, but itâs bothersome enough to cause symptoms or risks. In these cases, a condition might be effectively managed for a while with medication. […] Heart valve disease is usually progressive. The outlook for those who receive no treatment can be poor. But many who do receive treatment go on to live very full and healthy lives, especially when their cardiovascular risks are otherwise low. […] Evidence is also clear that, with proper treatment, most people enjoy an improvement in health and quality of life. […] As with all surgeries, there are risks. Because every patient is different, your doctor and your health care team will discuss your treatment options and recommend the best option for you. […] People who have damaged, repaired or replaced heart valves are at increased risk for developing an infection of the valve, known as infective endocarditis.
- #35 Aortic Valve Disease | UNC Heart Valve Clinichttps://www.med.unc.edu/medicine/cardiology/uncheartvalve/diseases-and-treatments/aortic-valve-disease/
Patients benefit greatly when they can be evaluated by a multidisciplinary team, who then together decide on the best treatment option and provide the highest level of care. […] When traditional open heart surgery is needed for your aortic valve, you want a team of surgeons who offer the highest level of care and the most treatment options.
- #36 Aortic stenosis – Symptoms, diagnosis and treatment | BMJ Best Practicehttps://bestpractice.bmj.com/topics/en-gb/325
Aortic stenosis (AS) is obstruction of blood flow across the aortic valve due to aortic valve fibrosis and calcification. […] Treatment of severe aortic stenosis with either a transcatheter or surgical valve prosthesis should be based primarily on symptoms or reduced ventricular systolic function. Earlier intervention may be considered if indicated by results of exercise testing, biomarkers, rapid progression, or the presence of very severe stenosis. […] Choice of intervention should be a shared decision-making process, taking account of lifetime risks and benefits associated with the type of approach (transcatheter versus surgical) and type of valve (mechanical vs. bioprosthetic). […] Following valve replacement, patients are subject to the complications of prosthetic valves.
- #37 Aortic Stenosis: Diagnosis and Treatment | AAFPhttps://www.aafp.org/pubs/afp/issues/2016/0301/p371.html
Aortic valve replacement is recommended for most symptomatic patients with evidence of significant aortic stenosis on echocardiography. […] Surgical valve replacement is the standard of care for patients at low to moderate surgical risk. […] Transcatheter aortic valve replacement may be considered in patients at high or prohibitive surgical risk. […] Aortic valve replacement is the only effective treatment for symptomatic, hemodynamically severe aortic stenosis. […] Aortic valve replacement is also recommended for asymptomatic patients with severe stenosis accompanied by LV systolic dysfunction (EF less than 50%). […] Aortic valve replacement is also indicated in asymptomatic patients with severe or even moderate stenosis who are undergoing cardiac surgery for other indications; this avoids the need for repeat surgery once the valve disease inevitably progresses.
- #38 Aortic Stenosis: Diagnosis and Treatment | AAFPhttps://www.aafp.org/pubs/afp/issues/2008/0915/p717.html
Aortic valve replacement is the only effective treatment for hemodynamically significant aortic stenosis. […] Aortic valve replacement is also recommended for asymptomatic patients with severe aortic stenosis accompanied by LV systolic dysfunction (i.e., ejection fraction of less than 50 percent). […] Watchful waiting is recommended in most asymptomatic patients with aortic stenosis, including those with severe disease. […] The average overall survival rate is two to three years in symptomatic patients without surgical treatment. […] Although there are no prospective randomized trials comparing aortic valve replacement with medical management, retrospective observational studies have shown that surgical repair leads to significant improvement in survival, usually accompanied by symptom improvement.
- #39 Antithrombotic Therapy in Patients With Valvular Heart Diseasehttps://www.uspharmacist.com/article/antithrombotic-therapy-in-patients-with-valvular-heart-disease
Most patients with VHD require surgery to repair or replace the valve and subsequent antithrombotic therapy to prevent clotting. […] After a prosthetic valve replacement, optimal antithrombotic therapy is recommended to prevent thromboembolism while minimizing the risk of bleeding. […] The therapeutic goals for treating VHD include reducing symptoms, repairing or replacing valves, and preventing blood clots. […] After the procedure, it is recommended that patients be started on antithrombotic therapy, such as warfarin or aspirin, to prevent thromboembolism. […] The choice of an antithrombotic agent is dependent upon the location of the replaced valve and the type of valve replacement(s). […] After valve replacement(s), antithrombotic therapy with an antiplatelet and vitamin K antagonist (VKA) is recommended with the dosing, duration, and international normalized ratio (INR) goal varying among bioprosthetic and mechanical replacements and TAVR.
- #40 Antithrombotic Therapy in Patients With Valvular Heart Diseasehttps://www.uspharmacist.com/article/antithrombotic-therapy-in-patients-with-valvular-heart-disease
It is recommended that patients with mechanical valves be on daily low-dose aspirin indefinitely and a VKA, but the INR goal depends on the type of mechanical valve and the presence of venous thromboembolism (VTE) risk factors. […] For patients post-TAVR, daily low-dose aspirin indefinitely and clopidogrel 75 mg daily for the first 3-6 months may be reasonable. […] Antiplatelet therapy is preferred over DOACs in these patients, as rivaroxaban 10 mg daily has been shown to put patients who are not indicated for anticoagulation for another reason at a higher risk of death or thromboembolic complications compared with antiplatelet therapy.
- #41 Aortic Valve Treatments | Division of Cardiologyhttps://www.columbiacardiology.org/patient-care/columbia-structural-heart-and-valve-center/patient-care/conditions-and-treatments/aortic-valve-treatments
In general, transcatheter procedures require less recovery time than surgical treatments. The majority of patients go home the next day after the procedure in good health, with no restrictions after one week. […] Patients may also take medications after treatment to control blood pressure or reduce the risk of blood clots.
- #42 Aortic Valve Disease | Duke Healthhttps://www.dukehealth.org/treatments/heart/aortic-valve-disease
Our heart surgeons offer minimally invasive techniques in which they reach and repair the aortic valve through small incisions — which may reduce blood loss, scarring, and the risk of infection while speeding your recovery. […] If you need a heart valve replacement, we offer mechanical valves made of carbon, as well as valves made from animal tissue. We screen and educate you on the best option for your needs and lifestyle. […] Our cardiac prevention and cardiac rehabilitation programs give you a personalized plan for recovery after surgery and help with long-term management of your heart health. Programs include exercise instruction, nutritional counseling, and lifestyle modification to optimize your health.
- #43 Aortic Stenosis: Symptoms & Treatmenthttps://my.clevelandclinic.org/health/diseases/23046-aortic-valve-stenosis
Valve replacement offers several options for people who cant have a valve repair. Aortic valve surgery replaces the valve with a donor valve (usually from a cow or pig), a mechanical valve or a bioprosthetic valve. […] Transcatheter methods like balloon valvuloplasty and TAVR have shorter recovery times. […] Treating bacterial infections promptly is the only way to prevent aortic stenosis. […] Your outlook with aortic stenosis depends on how quickly you get treatment. […] With timely or early treatment, the prognosis for aortic stenosis is good or excellent. […] If you have mild aortic stenosis or no symptoms, you may only need routine echocardiograms and regular follow-up appointments. […] If you have moderate aortic valve stenosis, you may need to monitor symptoms, get routine echocardiograms and limit your activity. […] With severe aortic valve stenosis, youll likely need follow-up visits after a valve repair or replacement.
- #44 Valvular Heart Disease | Heart Valve Disease | MedlinePlushttps://medlineplus.gov/heartvalvediseases.html
In some cases, valve replacement is necessary. There are 2 types of replacement valves: […] Biologic valves made from pig, cow, or human tissue. These valves tend to wear out after 10 to 15 years, but some may last longer. […] Mechanical (human-made) valves usually don’t wear out. But with a mechanical valve, you usually have to take blood thinners for the rest of your life to prevent blood clots. And your risk of endocarditis (a heart infection) is higher than with a biologic valve.
- #45 Understanding Your Heart Valve Treatment Options | American Heart Associationhttps://www.heart.org/en/health-topics/heart-valve-problems-and-disease/understanding-your-heart-valve-treatment-options
Recovery statistics are very good for people who receive proper treatment. […] Treatment for valve disease will include a plan to: Protect your heart from further damage. Assess your need for medication to help manage symptoms. Repair the valve problem if needed. Communicate steps for management, self-care and the importance of follow-up care. […] Generally, once itâs determined that a diseased heart valve needs treatment, the available choices are valve repair or replacement: Valve repair â preserves the patientâs valve and leaflets. Sometimes repairs require a minor surgical procedure and other times repairs need a more extensive surgery. Repair is most often possible mitral valve regurgitation and tricuspid valve regurgitation. Valve replacement â may include open heart surgery or a minimally invasive procedure such as TAVR (or TAVI).
- #46 Aortic Stenosis: Symptoms, Causes, and Treatmenthttps://patient.info/heart-health/heart-valves-and-valve-disease/aortic-stenosis
Open heart surgery to replace the valve. The replacement may be with a mechanical or a tissue valve. […] Transcatheter aortic valve implantation (TAVI) Plastic tubes (catheters) are inserted into the heart through various arteries. Using these tubes, an artificial valve is sited within the existing aortic valve. This procedure does not require open heart surgery. […] Stretching the stenosed valve (balloon valvuloplasty) This is an option that is occasionally considered. This also does not require open heart surgery. […] Balloon valvuloplasty has historically been used only in those who were unsuitable for valve replacement surgery because the improvement in the flow across the valve (following balloon valvuloplasty) often only lasts for a year or so. […] Surgery is usually advised for anyone with symptoms but referral for consideration of surgery is now advised for anyone with moderate or severe aortic stenosis, even if they have no symptoms. Surgical treatment has greatly improved the outlook (prognosis) in most people. Surgery has a very good success rate.
- #47 Aortic Stenosis: Diagnosis and Treatment | AAFPhttps://www.aafp.org/pubs/afp/issues/2008/0915/p717.html
Aortic valve replacement should be performed promptly in symptomatic patients. […] Patients with very severe aortic stenosis (aortic valve area of 0.6 cm2 or less or an aortic jet velocity of 5 m per second or more), a more rapid increase in aortic jet velocity over time (0.3 m per second or more per year), or severe valve calcification have a high risk of developing symptoms and of needing aortic valve replacement within the next one to two years. […] Aortic valve replacement should be considered if symptoms occur when the patient is at less than 80 percent of the predicted maximum heart rate or if the patient has an abnormal blood pressure response.
- #48 Heart Valve Disease Treatment Without Surgery: The Optionshttps://www.healthline.com/health/heart-valve-disease-treatment-without-surgery
Your doctor may recommend heart valve surgery if your condition is causing symptoms or if they think that it could lead to heart damage in the future. […] Mild heart valve disease might be manageable without surgery. Your doctor might recommend lifestyle changes, medications, or nonsurgical procedures.
- #49 Aortic Valve Stenosis Symptoms & Causes, Treatment for Aortic Stenosishttps://www.thekeyholeheartclinic.com/services/valve-disorders/aortic-valve/aortic-stenosis/
Aortic stenosis treatment is always the best answer. […] Therefore, the best aortic stenosis treatment available is surgery, and your doctor will be able to explain and recommend different kinds of aortic stenosis treatment London with you. […] The best treatment, by far, is replacement of your aortic valve by surgery. This treatment is effective, and will make you feel better, and live a longer, healthier life. […] Aortic stenosis treatment, such as aortic valve replacement, can be performed through keyhole incisions that either divide only a very small portion of the breastbone, or, in some cases, can avoid breastbone division altogether. […] The best treatment is still surgical replacement.
- #50 Bicuspid Aortic Valve Treatment | UVA Healthhttps://uvahealth.com/services/heart-valve-disease/bicuspid-aortic-valve-treatment
Medicines can’t repair your bicuspid aortic valve. But they can help with symptoms. […] When medicines arent working, you may need a procedure or surgery to fix your aortic valve. The best way to fix your aortic valve depends on lots of factors. We’ll go over with you the best choice for your condition. Options include: A procedure called transcatheter aortic valve replacement (TAVR), Open valve surgery. […] TAVR isn’t the right choice for everyone. If we can’t use TAVR, we can still repair or replace your bicuspid valve with a traditional open surgery. […] If you’re having bicuspid valve symptoms, it’s important to see an aortic valve expert. A bicuspid valve can make it harder for your heart to pump blood around your body. […] Without treatment, your body doesnt get the right amount of oxygen, and you may develop heart failure.