Materiały źródłowe

• #1 Toxic Shock Syndrome (TSS): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/15437-toxic-shock-syndrome

  Toxic shock syndrome (TSS) is a rare but serious condition caused by certain strains of bacteria. It causes toxins to spread into the bloodstream, causing severe organ damage or death. Knowing the signs of TSS and seeking prompt treatment results in the best outcomes. […] The symptoms of TSS happen suddenly and worsen quickly. However, most people recover if TSS is diagnosed and treated quickly. […] Symptoms of toxic shock syndrome may vary depending on the type of bacteria producing the toxins. They may include: Sudden high fever, chills, body aches and other flu-like symptoms. Nausea or vomiting. Watery diarrhea. Rash resembling a bad sunburn or red dots on your skin. Dizziness, lightheadedness or fainting. Low blood pressure (hypotension). Redness in your eyes (conjunctivitis) and throat. Peeling of the skin on the soles of your feet or palms of your hands.

• #2 Toxic Shock Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459345/

  Toxic shock syndrome (TSS) is an acute-onset illness characterized by fever, hypotension, sunburn-like rash, and end-organ damage. […] TSS typically presents with rapid onset of fever, rash, and hypotension. It may be preceded by a prodrome of fever and chills with nausea and vomiting as well as nonspecific symptoms such as myalgias, headache, or symptoms of pharyngitis (e.g., a sore throat, painful swallowing), which then progresses to sepsis and organ dysfunction. […] Early recognition and antibiotic administration are key to improving patient outcomes and reducing mortality. […] The case fatality rate of Streptococcal TSS may exceed 50%, particularly with delayed diagnosis; whereas non-streptococcal TSS is less than 3%. […] A small study in France showed that non-menstrual Toxic Shock Syndrome had a higher mortality (22%) than that of the menstrual toxic shock syndrome (0%). However, this was a small case series of 55 patients. […] Many of the complications from toxic shock syndrome are also part of the diagnostic criteria: end organ damage including renal failure, liver failure, coagulopathy, etc. In addition to these, glomerulonephritis and rheumatic fever can also occur.

• #3 Toxic Shock Syndrome (TSS) – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/gram-positive-cocci/toxic-shock-syndrome-tss

  Toxic shock syndrome is caused by staphylococcal or streptococcal exotoxins. Manifestations include high fever, hypotension, diffuse erythematous rash, and multiple organ dysfunction, which may rapidly progress to severe and intractable shock. […] Onset of toxic shock syndrome is sudden, with […] Fever (39 to 40.5 C, which remains elevated) […] Hypotension (which can be refractory) […] A diffuse macular erythroderma […] Involvement of at least 2 other organ systems. […] Staphylococcal TSS is likely to cause vomiting, diarrhea, myalgia, elevated creatine kinase, mucositis, hepatic damage, thrombocytopenia, and confusion. […] The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. […] Streptococcal TSS commonly causes acute respiratory distress syndrome (in about 55% of patients), coagulopathy, and hepatic damage and is more likely to cause high fever, malaise, tachycardia, tachypnea, and, at the site of a soft-tissue infection, severe pain. […] TSS may progress within 48 hours to syncope, tissue necrosis, shock, disseminated coagulation, multisystem organ failure, and death.

• #4 Toxic shock syndrome – Wikipedia

  https://en.wikipedia.org/wiki/Toxic_shock_syndrome

  Symptoms may include fever, rash, skin peeling, and low blood pressure. […] There may also be symptoms related to the specific underlying infection such as mastitis, osteomyelitis, necrotising fasciitis, or pneumonia. […] TSS is typically caused by bacteria of the Streptococcus pyogenes or Staphylococcus aureus type, though others may also be involved. […] Risk factors for the staphylococcal type include the use of very absorbent tampons, skin lesions in young children characterized by fever, low blood pressure, rash, vomiting and/or diarrhea, and multiorgan failure. […] The overall risk of death is about 50% in streptococcal disease, and 5% in staphylococcal disease. […] Death may occur within 2 days. […] Symptoms of toxic shock syndrome (TSS) vary depending on the underlying cause.

• #5 Staphylococcal toxic shock syndrome – UpToDate

  https://www.uptodate.com/contents/staphylococcal-toxic-shock-syndrome

  Staphylococcal toxic shock syndrome (TSS) is a clinical illness characterized by rapid onset of fever, rash, hypotension, and multiorgan system involvement. […] The clinical illness arose during menstruation and was associated with use of highly absorbent tampons. […] TSS associated with S. aureus was first described in a series of pediatric cases in 1978. […] The incidence rose sharply in 1980; more than 800 cases of menses-related TSS occurred, largely among young women. […] The observed increase in the number of cases may reflect increased recognition due to active laboratory testing for toxin-producing strains, rather than an overall increase in incidence.

• #6 FURTHER INFORMATION – TSSIS

  https://www.tssis.com/further_information/

  TSS can occur in any member of the population, regardless of age or sex. It is usually seen as a consequence of localised infections following scalds, burns, wounds, surgery, piercings, chicken pox spots, childbirth etc. […] The condition will rapidly make a person become very unwell indeed where in addition to aches, pains, diarrhoea and vomiting, they may develop a high fever, low blood pressure, confusion and dizziness, and often sporadic patches of a sunburn like rash. […] Without medical help TSS rapidly becomes very serious and sadly a small number of people die each year from TSS. […] Some of the symptoms of TSS are like very severe flu and include some or all of the following: Sudden high fever, Vomiting, Diarrhoea, Dizziness, Fainting or feeling faint, Muscle aches, Patches of sunburn-like rash, Confusion.

• #7 Toxic Shock Syndrome (TSS) – Basics & Causes

  https://www.webmd.com/women/understanding-toxic-shock-syndrome-basics

  When it starts, TSS causes the same symptoms as a lot of other less serious illnesses. They come on suddenly and include: A high fever and chills, Muscle aches, Vomiting and diarrhea, Headache, Sore throat. […] Symptoms get worse fast, and you can also have: Low blood pressure, A rash that looks like a sunburn, especially on your palms and bottoms of your feet, Red eyes, mouth, and throat, Confusion, Seizures. […] After about a week, the rash from TSS can cause your skin to peel in large sheets. […] You may feel like you have the flu at first. But you’ll quickly feel much sicker as the toxins from the infection start to damage your organs. Pay special attention to symptoms like a sudden high fever and vomiting if you’re on your period or if you have an open wound or a skin infection. If you’re using a tampon, menstrual sponge, diaphragm, or cervical cap when you get sick, take it out right away, even before you call the doctor. […] TSS starts out with mild flu-like symptoms that get worse fast. You should suspect it if you suddenly feel very sick all over your body, especially if you’ve been using tampons or have an infected cut or burn.

• #8 Toxic Shock Syndrome Clinical Presentation: History, Physical Examination, Complications

  https://emedicine.medscape.com/article/169177-clinical

  Although the clinical manifestations of toxic shock syndrome (TSS) can be diverse, the possibility of toxic shock should be considered in any individual who presents with sudden onset of fever, rash, hypotension, and organ failure. […] Staphylococcal TSS most commonly occurs in women, usually those who are using tampons. TSS develops within 5 days after the onset of menstruation. […] Approximately 20% of patients with staphylococcal TSS have an influenza-like syndrome characterized by the following: Fever, Chills, Myalgia, Nausea, Vomiting, Diarrhea. […] The most common initial symptom of patients with streptococcal TSS is diffuse or localized pain that is abrupt and severe. Other manifestations include the following: Influenza-like syndrome, Fever, Confusion, Signs of soft tissue infection.

• #9

• #10 Toxic Shock Syndrome (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/toxic-shock.html

  Toxic shock syndrome starts suddenly, often with a high fever (temperature at least 102F [38.8C]). […] Other signs include vomiting, confusion, weakness, tiredness, peeing less than usual, and being thirsty. A person also might have bloodshot eyes and an unusual redness under the eyelids or inside the mouth (and in the vagina in females). The area around an infected wound can become swollen, red, and tender. […] Symptoms of toxic shock syndrome come on suddenly. Call your doctor right away if your child gets a sudden high fever, feels faint, or has other signs of TSS.

• #11 Toxic Shock Syndrome (TSS): Signs and Symptoms

  https://www.health.com/toxic-shock-syndrome-symptoms-8353272

  Toxic shock syndrome (TSS) is a rare but serious, life-threatening condition that occurs when bacteria like Staphylococcus aureus (known as staph) or Streptococcus pyogenes (known as strep A) release harmful toxins into the blood. If you develop this infection, it’s common to experience flu-like symptoms like high fever, sore throat, and fatigue. But without treatment, symptoms can worsen and cause seizures and organ failure. […] TSS affects less than 1% of people in the U.S. each year, but if you or a loved one experiences symptoms of the condition, it’s necessary to see a healthcare provider urgently to prevent serious complications. […] Early symptoms of TSS may include: Fever higher than 102 degrees Fahrenheit or 38.9 degrees Celcius, Fatigue, Muscle aches or weakness, Sore throat or cough, Headache, Runny nose, Nausea or vomiting, Diarrhea.

• #12 Toxic Shock Syndrome: Symptoms, Treatment, and Prevention

  https://www.webmd.com/women/what-are-toxic-shock-syndrome-symptoms

  Toxic shock syndrome (TSS) is a rare but serious condition thats caused when your immune system reacts to toxins produced by bacteria. TSS occurs when these toxins enter into your bloodstream, where your bodys reaction can affect many systems in your body at once. […] TSS symptoms usually come on quickly, about 2 days after the bacteria infects you. The way TSS affects your body depends on the type of bacteria causing your condition. […] Generally, TSS causes: Fever, Rash, Low blood pressure, Kidney problems or failure, Respiratory problems or failure, Confusion. […] Staphylococcal TSS happens most often in women. This type of TSS causes: Fever above 102 F, Headache, Fatigue, Flat, red rash like a sunburn on most of your body, Vomiting, Diarrhea, Muscle pain, Redder than usual mouth, eyes, and vagina, Bruising, Low urine output.

• #13 Department of Health | Communicable Disease Service | Toxic Shock Syndrome

  https://www.nj.gov/health/cd/topics/tss.shtml

  Toxic shock syndrome (TSS) is a rare, but potentially serious illness that can develop quickly. […] Early symptoms may include low fever, muscle aches, chills, feeling tired, and headache. […] As TSS progresses symptoms may include high fever, vomiting, rash, red eyes/lips/tongue, low blood pressure, and mental confusion.

• #14 Toxic shock syndrome | HealthLink BC

  https://www.healthlinkbc.ca/healthlinkbc-files/toxic-shock-syndrome

  Symptoms of TSS include flu-like symptoms such as fever, headache and muscle soreness. These symptoms will develop quickly and are severe. Other symptoms may include pain at the site of a wound, vomiting and diarrhea, signs of shock including low blood pressure and light-headedness, shortness of breath and a sunburn-like rash. […] In general, TSS symptoms can develop as soon as 12 hours after a surgical procedure. Symptoms usually develop in 3 to 5 days in individuals who are menstruating and using tampons or menstrual cups. […] If you experience the above symptoms after using tampons, a menstrual cup or after a surgery or skin injury, contact your health care provider immediately.

• #15 Toxic Shock Syndrome (TSS): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/15437-toxic-shock-syndrome

  Toxic shock syndrome (TSS) is a rare but serious condition caused by certain strains of bacteria. It causes toxins to spread into the bloodstream, causing severe organ damage or death. Knowing the signs of TSS and seeking prompt treatment results in the best outcomes. […] The symptoms of TSS happen suddenly and worsen quickly. However, most people recover if TSS is diagnosed and treated quickly. […] Symptoms of toxic shock syndrome may vary depending on the type of bacteria producing the toxins. They may include: Sudden high fever, chills, body aches and other flu-like symptoms. Nausea or vomiting. Watery diarrhea. Rash resembling a bad sunburn or red dots on your skin. Dizziness, lightheadedness or fainting. Low blood pressure (hypotension). Redness in your eyes (conjunctivitis) and throat. Peeling of the skin on the soles of your feet or palms of your hands.

• #16 Toxic Shock Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459345/

  Toxic shock syndrome (TSS) is an acute-onset illness characterized by fever, hypotension, sunburn-like rash, and end-organ damage. […] TSS typically presents with rapid onset of fever, rash, and hypotension. It may be preceded by a prodrome of fever and chills with nausea and vomiting as well as nonspecific symptoms such as myalgias, headache, or symptoms of pharyngitis (e.g., a sore throat, painful swallowing), which then progresses to sepsis and organ dysfunction. […] Early recognition and antibiotic administration are key to improving patient outcomes and reducing mortality. […] The case fatality rate of Streptococcal TSS may exceed 50%, particularly with delayed diagnosis; whereas non-streptococcal TSS is less than 3%. […] A small study in France showed that non-menstrual Toxic Shock Syndrome had a higher mortality (22%) than that of the menstrual toxic shock syndrome (0%). However, this was a small case series of 55 patients. […] Many of the complications from toxic shock syndrome are also part of the diagnostic criteria: end organ damage including renal failure, liver failure, coagulopathy, etc. In addition to these, glomerulonephritis and rheumatic fever can also occur.

• #17 Toxic shock syndrome | HealthLink BC

  https://www.healthlinkbc.ca/healthlinkbc-files/toxic-shock-syndrome

  Symptoms of TSS include flu-like symptoms such as fever, headache and muscle soreness. These symptoms will develop quickly and are severe. Other symptoms may include pain at the site of a wound, vomiting and diarrhea, signs of shock including low blood pressure and light-headedness, shortness of breath and a sunburn-like rash. […] In general, TSS symptoms can develop as soon as 12 hours after a surgical procedure. Symptoms usually develop in 3 to 5 days in individuals who are menstruating and using tampons or menstrual cups. […] If you experience the above symptoms after using tampons, a menstrual cup or after a surgery or skin injury, contact your health care provider immediately.

• #18 Toxic shock syndrome | HealthLink BC

  https://www.healthlinkbc.ca/healthlinkbc-files/toxic-shock-syndrome

  Symptoms of TSS include flu-like symptoms such as fever, headache and muscle soreness. These symptoms will develop quickly and are severe. Other symptoms may include pain at the site of a wound, vomiting and diarrhea, signs of shock including low blood pressure and light-headedness, shortness of breath and a sunburn-like rash. […] In general, TSS symptoms can develop as soon as 12 hours after a surgical procedure. Symptoms usually develop in 3 to 5 days in individuals who are menstruating and using tampons or menstrual cups. […] If you experience the above symptoms after using tampons, a menstrual cup or after a surgery or skin injury, contact your health care provider immediately.

• #19 Toxic Shock Syndrome (TSS): Signs and Symptoms

  https://www.health.com/toxic-shock-syndrome-symptoms-8353272

  These TSS symptoms come suddenly and can worsen within a matter of 24 to 48 hours. If proper rest and drinking more water aren’t improving your symptoms or you notice that your illness may be getting worse, it’s important to see a healthcare provider for a proper diagnosis. […] Low blood pressure clinically known as hypotension occurs when your blood flows through your blood vessels at a lower-than-normal pressure for your body to function properly. […] With TSS, the drop in BP happens fairly quickly. This symptom occurs because toxins from TSS can cause your blood vessels to widen and make them „leaky.” […] Hypotension is the first major sign of a medical emergency. If your blood pressure stays too low for too long, your vital organs won’t get enough blood and oxygen to function. […] It’s important to note that not everyone with TSS gets a skin rash. But if your rash occurs alongside symptoms like fever and low blood pressure, this could be a sign of TSS.

• #20 Toxic Shock Syndrome (TSS) – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/gram-positive-cocci/toxic-shock-syndrome-tss

  Toxic shock syndrome is caused by staphylococcal or streptococcal exotoxins. Manifestations include high fever, hypotension, diffuse erythematous rash, and multiple organ dysfunction, which may rapidly progress to severe and intractable shock. […] Onset of toxic shock syndrome is sudden, with […] Fever (39 to 40.5 C, which remains elevated) […] Hypotension (which can be refractory) […] A diffuse macular erythroderma […] Involvement of at least 2 other organ systems. […] Staphylococcal TSS is likely to cause vomiting, diarrhea, myalgia, elevated creatine kinase, mucositis, hepatic damage, thrombocytopenia, and confusion. […] The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. […] Streptococcal TSS commonly causes acute respiratory distress syndrome (in about 55% of patients), coagulopathy, and hepatic damage and is more likely to cause high fever, malaise, tachycardia, tachypnea, and, at the site of a soft-tissue infection, severe pain. […] TSS may progress within 48 hours to syncope, tissue necrosis, shock, disseminated coagulation, multisystem organ failure, and death.

• #21 About Streptococcal Toxic Shock Syndrome | Group A Strep | CDC

  https://www.cdc.gov/group-a-strep/about/streptococcal-toxic-shock-syndrome.html

  Streptococcal toxic shock syndrome (STSS) is a rare, but serious bacterial infection. STSS can develop very quickly into a life-threatening emergency. People with STSS need immediate care in a hospital and antibiotics. First symptoms of STSS often include: Fever and chills, Muscle aches, Nausea and vomiting. After the first symptoms start, it usually only takes about 24 to 48 hours for low blood pressure to develop. Once this happens, STSS quickly gets much more serious: Hypotension (low blood pressure), Organ failure (other signs that organs are not working), Tachycardia (faster than normal heart rate), Tachypnea (rapid breathing). STSS often results in complications from organs shutting down and the body going into shock. Even with treatment, STSS can be deadly. Out of 10 people with STSS, as many as 3 people will die from the infection. Healthcare providers diagnose STSS when the patient has all the following: A group A strep infection, Low blood pressure, Problems with 2 or more organs. People with STSS need care in a hospital. They often need fluids given through a vein and other treatments to help treat shock and organ failure. Many people with STSS also need surgery to remove infected tissue.

• #22 Toxic shock syndrome

  https://www.nhs.uk/conditions/toxic-shock-syndrome/

  Toxic shock syndrome (TSS) can come on quickly. […] Symptoms include: a high temperature, muscle aches, a raised skin rash that feels like sandpaper, flu-like symptoms. […] You think you might have toxic shock syndrome and you have any of these symptoms: a high temperature, feeling shivery, with muscle aches, vomiting and diarrhoea, severe pain in your arms or legs, or all over your body, a rash that feels rough like sandpaper the rash may look red, which can be harder to see on brown or black skin, the palms of your hands, soles of your feet, tongue and the whites of your eyes turn bright red, swollen or peeling skin, feeling sick, dizzy or confused.

• #23 Toxic Shock Syndrome Clinical Presentation: History, Physical Examination, Complications

  https://emedicine.medscape.com/article/169177-clinical

  Fever is the most common presenting sign, although patients in shock may present with hypothermia. […] Patients become severely hypotensive and do not respond to intravenous fluid administration. Renal dysfunction progresses or persists in all patients, precedes shock in many patients, and is apparent early. […] Approximately 80% of patients have clinical signs of soft tissue infection (eg, localized swelling, erythema), which usually progresses to necrotizing fasciitis or myositis. […] Progression of soft tissue swelling to vesicle or bullous formation is an ominous sign and suggests streptococcal shock syndrome. […] The possibility of staphylococcal TSS should be considered in any patient who presents with a sudden onset of fever, rash, and hypotension. […] Common presenting symptoms and frequency of streptococcal TTS are as follows: Tachycardia (80%), Fever (70-81%), Hypotension (44-65%), Confusion (55%), Localized erythema (44-65%), Localized swelling and erythema (30-75%).

• #24 About Streptococcal Toxic Shock Syndrome | Group A Strep | CDC

  https://www.cdc.gov/group-a-strep/about/streptococcal-toxic-shock-syndrome.html

  Streptococcal toxic shock syndrome (STSS) is a rare, but serious bacterial infection. STSS can develop very quickly into a life-threatening emergency. People with STSS need immediate care in a hospital and antibiotics. First symptoms of STSS often include: Fever and chills, Muscle aches, Nausea and vomiting. After the first symptoms start, it usually only takes about 24 to 48 hours for low blood pressure to develop. Once this happens, STSS quickly gets much more serious: Hypotension (low blood pressure), Organ failure (other signs that organs are not working), Tachycardia (faster than normal heart rate), Tachypnea (rapid breathing). STSS often results in complications from organs shutting down and the body going into shock. Even with treatment, STSS can be deadly. Out of 10 people with STSS, as many as 3 people will die from the infection. Healthcare providers diagnose STSS when the patient has all the following: A group A strep infection, Low blood pressure, Problems with 2 or more organs. People with STSS need care in a hospital. They often need fluids given through a vein and other treatments to help treat shock and organ failure. Many people with STSS also need surgery to remove infected tissue.

• #25 Warning Signs of Toxic Shock Syndrome | Aunt Flow

  https://goauntflow.com/blog/warning-signs-of-toxic-shock-syndrome/

  Warning signs include flu-like symptoms. Here are the specifics of the most common symptoms of TSS: […] A sudden fever of 102°F (38.9°C) or higher […] Hypotension (low blood pressure) […] A sunburn-like rash […] Severe, persistent muscle pain or headaches […] Gastrointestinal issues, such as vomiting or diarrhea […] Confusion or altered mental state. […] If you’re experiencing these symptoms, remove your tampon and contact your doctor immediately.

• #26 Toxic Shock Syndrome (TSS): Signs and Symptoms

  https://www.health.com/toxic-shock-syndrome-symptoms-8353272

  These TSS symptoms come suddenly and can worsen within a matter of 24 to 48 hours. If proper rest and drinking more water aren’t improving your symptoms or you notice that your illness may be getting worse, it’s important to see a healthcare provider for a proper diagnosis. […] Low blood pressure clinically known as hypotension occurs when your blood flows through your blood vessels at a lower-than-normal pressure for your body to function properly. […] With TSS, the drop in BP happens fairly quickly. This symptom occurs because toxins from TSS can cause your blood vessels to widen and make them „leaky.” […] Hypotension is the first major sign of a medical emergency. If your blood pressure stays too low for too long, your vital organs won’t get enough blood and oxygen to function. […] It’s important to note that not everyone with TSS gets a skin rash. But if your rash occurs alongside symptoms like fever and low blood pressure, this could be a sign of TSS.

• #27 Toxic shock syndrome – Wikipedia

  https://en.wikipedia.org/wiki/Toxic_shock_syndrome

  TSS resulting from infection with the bacterium Staphylococcus aureus typically manifests in otherwise healthy individuals via signs and symptoms including high fever, accompanied by low blood pressure, malaise and confusion, which can rapidly progress to stupor, coma, and multiple organ failure. […] The characteristic rash, often seen early in the course of illness, resembles a sunburn. […] In patients who survive, the rash desquamates (peels off) after 10-21 days. […] STSS caused by the bacterium Streptococcus pyogenes, or TSLS, typically presents in people with pre-existing skin infections with the bacteria. These individuals often experience severe pain at the site of the skin infection, followed by rapid progression of symptoms as described above for TSS.

• #28 Toxic Shock Syndrome Symptoms, Signs, Causes & Treatment

  https://www.emedicinehealth.com/toxic_shock_syndrome/article_em.htm

  Toxic shock syndrome (TSS) is a rare, life-threatening illness that is caused by toxins (poisons) that circulate in the bloodstream. […] People with toxic shock syndrome develop high fever, rash, low blood pressure, and failure of multiple organ systems (at least three systems) in the body. […] Toxic shock syndrome commonly causes a red strawberry tongue. […] Many people with toxic shock syndrome experience a two- to three-day period of mild symptoms before they develop the disease. These mild symptoms may include low-grade fever, muscle aches, chills, and malaise (a feeling of general discomfort, uneasiness, or ill health). […] All people with TSS have a fever and a rash, as well as symptoms in at least three other organ systems. These symptoms or findings may include the following: Fever greater than 102 F (38.9 C), Rash (The rash of toxic shock syndrome is a red sunburn-like rash that covers most of the body. It is flat, not raised, and turns white if pressed. The rash may be difficult to see in dark-skinned people. Redness of the eyes, the lips, and the tongue [strawberry tongue] may also occur. The rash also can occur on the palms and soles of the feet.), Headache (very common), Muscle aches, Sore throat, Cough, Nausea and vomiting, Diarrhea (profuse and watery), Abdominal pain, Lightheadedness or fainting (especially on standing up), Confusion or disorientation, Low blood pressure (systolic less than 90 mm Hg). […] Toxic shock syndrome is a serious, life-threatening disease. Early medical care is the key to ensuring the best possibility of survival. People who survive toxic shock syndrome usually improve within 48 hours and can be discharged from the hospital within one week.

• #29 Toxic Shock Syndrome (TSS) | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/toxic-shock-syndrome

  Toxic shock syndrome (TSS) is a rare but life-threatening complication of bacterial infection or colonization. TSS can affect anyone, male or female. It generally is characterized by high fever with or without chills, a sunburn-like rash, and shock (low blood pressure and/or very high heart rate). […] Symptoms usually evolve very quickly and treatment almost always requires hospitalization, intravenous antibiotics, and IV fluids, often with medicines to increase blood pressure. […] While symptoms may vary from child to child, the most common symptoms are listed below. It can look like a severe flu. Symptoms overlap between the two types of TSS, but a medical doctor can help distinguish the two infections with blood tests. […] For staphylococcal TSS: High fever, Chills, Malaise (uneasiness and despair), Headache, Fatigue, A red, flat rash that covers most of the areas of the body, Low blood pressure, Vomiting, Diarrhea, Muscle pain, Increased blood flow to mouth, eyes, and vagina, making them appear red, Decreased urine output and sediment in urine, Decreased liver function, Bruising, Disorientation and confusion, Eventual sloughing of the skin (especially the palms and soles) one to two weeks after the onset of symptoms.

• #30 Toxic Shock Syndrome (TSS): Signs and Symptoms

  https://www.health.com/toxic-shock-syndrome-symptoms-8353272

  These TSS symptoms come suddenly and can worsen within a matter of 24 to 48 hours. If proper rest and drinking more water aren’t improving your symptoms or you notice that your illness may be getting worse, it’s important to see a healthcare provider for a proper diagnosis. […] Low blood pressure clinically known as hypotension occurs when your blood flows through your blood vessels at a lower-than-normal pressure for your body to function properly. […] With TSS, the drop in BP happens fairly quickly. This symptom occurs because toxins from TSS can cause your blood vessels to widen and make them „leaky.” […] Hypotension is the first major sign of a medical emergency. If your blood pressure stays too low for too long, your vital organs won’t get enough blood and oxygen to function. […] It’s important to note that not everyone with TSS gets a skin rash. But if your rash occurs alongside symptoms like fever and low blood pressure, this could be a sign of TSS.

• #31 Toxic Shock Syndrome: Symptoms, Treatment, and Prevention

  https://www.webmd.com/women/what-are-toxic-shock-syndrome-symptoms

  Toxic shock syndrome (TSS) is a rare but serious condition thats caused when your immune system reacts to toxins produced by bacteria. TSS occurs when these toxins enter into your bloodstream, where your bodys reaction can affect many systems in your body at once. […] TSS symptoms usually come on quickly, about 2 days after the bacteria infects you. The way TSS affects your body depends on the type of bacteria causing your condition. […] Generally, TSS causes: Fever, Rash, Low blood pressure, Kidney problems or failure, Respiratory problems or failure, Confusion. […] Staphylococcal TSS happens most often in women. This type of TSS causes: Fever above 102 F, Headache, Fatigue, Flat, red rash like a sunburn on most of your body, Vomiting, Diarrhea, Muscle pain, Redder than usual mouth, eyes, and vagina, Bruising, Low urine output.

• #32 Toxic shock syndrome: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000653.htm

  Toxic shock syndrome is a serious and potentially life-threatening disease that involves fever, shock, and problems with several body organs. […] Symptoms include: Confusion, Diarrhea, General ill feeling, Headaches, High fever, sometimes accompanied by chills, Low blood pressure, Muscle aches, Nausea and vomiting, Organ failure (most often kidneys and liver), Redness of eyes, mouth, throat, Seizures, Widespread red rash that looks like a sunburn — skin peeling occurs 1 or 2 weeks after the rash, particularly on the palms of the hand or bottom of the feet. […] Toxic shock syndrome may be deadly in up to 50% of cases. The condition may return in those who survive. […] Toxic shock syndrome is a medical emergency. Seek medical help right away if you develop a rash, fever, and feel ill, particularly during menstruation and tampon use or if you have had recent surgery.

• #33 Toxic Shock Syndrome (TSS) – Basics & Causes

  https://www.webmd.com/women/understanding-toxic-shock-syndrome-basics

  When it starts, TSS causes the same symptoms as a lot of other less serious illnesses. They come on suddenly and include: A high fever and chills, Muscle aches, Vomiting and diarrhea, Headache, Sore throat. […] Symptoms get worse fast, and you can also have: Low blood pressure, A rash that looks like a sunburn, especially on your palms and bottoms of your feet, Red eyes, mouth, and throat, Confusion, Seizures. […] After about a week, the rash from TSS can cause your skin to peel in large sheets. […] You may feel like you have the flu at first. But you’ll quickly feel much sicker as the toxins from the infection start to damage your organs. Pay special attention to symptoms like a sudden high fever and vomiting if you’re on your period or if you have an open wound or a skin infection. If you’re using a tampon, menstrual sponge, diaphragm, or cervical cap when you get sick, take it out right away, even before you call the doctor. […] TSS starts out with mild flu-like symptoms that get worse fast. You should suspect it if you suddenly feel very sick all over your body, especially if you’ve been using tampons or have an infected cut or burn.

• #34 Toxic Shock Syndrome (TSS): Signs and Symptoms

  https://www.health.com/toxic-shock-syndrome-symptoms-8353272

  These TSS symptoms come suddenly and can worsen within a matter of 24 to 48 hours. If proper rest and drinking more water aren’t improving your symptoms or you notice that your illness may be getting worse, it’s important to see a healthcare provider for a proper diagnosis. […] Low blood pressure clinically known as hypotension occurs when your blood flows through your blood vessels at a lower-than-normal pressure for your body to function properly. […] With TSS, the drop in BP happens fairly quickly. This symptom occurs because toxins from TSS can cause your blood vessels to widen and make them „leaky.” […] Hypotension is the first major sign of a medical emergency. If your blood pressure stays too low for too long, your vital organs won’t get enough blood and oxygen to function. […] It’s important to note that not everyone with TSS gets a skin rash. But if your rash occurs alongside symptoms like fever and low blood pressure, this could be a sign of TSS.

• #35 Toxic Shock Syndrome (TSS): Signs and Symptoms

  https://www.health.com/toxic-shock-syndrome-symptoms-8353272

  When toxins from TSS widen the blood vessels in the skin, a flat, red, sunburn-like rash can appear. […] Aside from a skin rash, TSS can cause also cause redness in the whites of the eyes, mouth, throat, or vagina. […] Confusion occurs when you don’t know where you are, who you are, or what time it is. […] Seizures are sudden, uncontrolled disturbances that can affect the chemicals in your brain. […] Organ dysfunction is a severe and potentially life-threatening complication of TSS. […] If your flu-like symptoms persist and you begin to notice symptoms like a rash, redness, low blood pressure, confusion, and seizures, it’s necessary to get the medical care you need immediately. […] TSS typically requires hospitalization in an intensive care unit (ICU) and treatment such as intravenous (IV) antibiotics and fluids.

• #36 Toxic Shock Syndrome (TSS) | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/toxic-shock-syndrome

  Toxic shock syndrome (TSS) is a rare but life-threatening complication of bacterial infection or colonization. TSS can affect anyone, male or female. It generally is characterized by high fever with or without chills, a sunburn-like rash, and shock (low blood pressure and/or very high heart rate). […] Symptoms usually evolve very quickly and treatment almost always requires hospitalization, intravenous antibiotics, and IV fluids, often with medicines to increase blood pressure. […] While symptoms may vary from child to child, the most common symptoms are listed below. It can look like a severe flu. Symptoms overlap between the two types of TSS, but a medical doctor can help distinguish the two infections with blood tests. […] For staphylococcal TSS: High fever, Chills, Malaise (uneasiness and despair), Headache, Fatigue, A red, flat rash that covers most of the areas of the body, Low blood pressure, Vomiting, Diarrhea, Muscle pain, Increased blood flow to mouth, eyes, and vagina, making them appear red, Decreased urine output and sediment in urine, Decreased liver function, Bruising, Disorientation and confusion, Eventual sloughing of the skin (especially the palms and soles) one to two weeks after the onset of symptoms.

• #37 Toxic Shock Syndrome (TSS) | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/toxic-shock-syndrome

  Toxic shock syndrome (TSS) is a rare but life-threatening complication of bacterial infection or colonization. TSS can affect anyone, male or female. It generally is characterized by high fever with or without chills, a sunburn-like rash, and shock (low blood pressure and/or very high heart rate). […] Symptoms usually evolve very quickly and treatment almost always requires hospitalization, intravenous antibiotics, and IV fluids, often with medicines to increase blood pressure. […] While symptoms may vary from child to child, the most common symptoms are listed below. It can look like a severe flu. Symptoms overlap between the two types of TSS, but a medical doctor can help distinguish the two infections with blood tests. […] For staphylococcal TSS: High fever, Chills, Malaise (uneasiness and despair), Headache, Fatigue, A red, flat rash that covers most of the areas of the body, Low blood pressure, Vomiting, Diarrhea, Muscle pain, Increased blood flow to mouth, eyes, and vagina, making them appear red, Decreased urine output and sediment in urine, Decreased liver function, Bruising, Disorientation and confusion, Eventual sloughing of the skin (especially the palms and soles) one to two weeks after the onset of symptoms.

• #38 Toxic Shock Syndrome (TSS) – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/gram-positive-cocci/toxic-shock-syndrome-tss

  Toxic shock syndrome is caused by staphylococcal or streptococcal exotoxins. Manifestations include high fever, hypotension, diffuse erythematous rash, and multiple organ dysfunction, which may rapidly progress to severe and intractable shock. […] Onset of toxic shock syndrome is sudden, with […] Fever (39 to 40.5 C, which remains elevated) […] Hypotension (which can be refractory) […] A diffuse macular erythroderma […] Involvement of at least 2 other organ systems. […] Staphylococcal TSS is likely to cause vomiting, diarrhea, myalgia, elevated creatine kinase, mucositis, hepatic damage, thrombocytopenia, and confusion. […] The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. […] Streptococcal TSS commonly causes acute respiratory distress syndrome (in about 55% of patients), coagulopathy, and hepatic damage and is more likely to cause high fever, malaise, tachycardia, tachypnea, and, at the site of a soft-tissue infection, severe pain. […] TSS may progress within 48 hours to syncope, tissue necrosis, shock, disseminated coagulation, multisystem organ failure, and death.

• #39 Toxic Shock Syndrome (TSS) | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/toxic-shock-syndrome

  For streptococcal TSS: Low blood pressure, Decreased kidney function, Bleeding problems, Bruising, Red, flat rash that covers large areas of the body, Decreased liver function, Decreased urine output and sediment in urine, Difficulty breathing, Eventual sloughing of the skin (especially the palms and soles) one to two weeks after the onset of symptoms.

• #40 Toxic shock syndrome: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000653.htm

  Toxic shock syndrome is a serious and potentially life-threatening disease that involves fever, shock, and problems with several body organs. […] Symptoms include: Confusion, Diarrhea, General ill feeling, Headaches, High fever, sometimes accompanied by chills, Low blood pressure, Muscle aches, Nausea and vomiting, Organ failure (most often kidneys and liver), Redness of eyes, mouth, throat, Seizures, Widespread red rash that looks like a sunburn — skin peeling occurs 1 or 2 weeks after the rash, particularly on the palms of the hand or bottom of the feet. […] Toxic shock syndrome may be deadly in up to 50% of cases. The condition may return in those who survive. […] Toxic shock syndrome is a medical emergency. Seek medical help right away if you develop a rash, fever, and feel ill, particularly during menstruation and tampon use or if you have had recent surgery.

• #41 Toxic Shock Syndrome: Symptoms, Treatment, and Prevention

  https://www.webmd.com/women/what-are-toxic-shock-syndrome-symptoms

  Toxic shock syndrome (TSS) is a rare but serious condition thats caused when your immune system reacts to toxins produced by bacteria. TSS occurs when these toxins enter into your bloodstream, where your bodys reaction can affect many systems in your body at once. […] TSS symptoms usually come on quickly, about 2 days after the bacteria infects you. The way TSS affects your body depends on the type of bacteria causing your condition. […] Generally, TSS causes: Fever, Rash, Low blood pressure, Kidney problems or failure, Respiratory problems or failure, Confusion. […] Staphylococcal TSS happens most often in women. This type of TSS causes: Fever above 102 F, Headache, Fatigue, Flat, red rash like a sunburn on most of your body, Vomiting, Diarrhea, Muscle pain, Redder than usual mouth, eyes, and vagina, Bruising, Low urine output.

• #42 Toxic Shock Syndrome (TSS) – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/gram-positive-cocci/toxic-shock-syndrome-tss

  Toxic shock syndrome is caused by staphylococcal or streptococcal exotoxins. Manifestations include high fever, hypotension, diffuse erythematous rash, and multiple organ dysfunction, which may rapidly progress to severe and intractable shock. […] Onset of toxic shock syndrome is sudden, with […] Fever (39 to 40.5 C, which remains elevated) […] Hypotension (which can be refractory) […] A diffuse macular erythroderma […] Involvement of at least 2 other organ systems. […] Staphylococcal TSS is likely to cause vomiting, diarrhea, myalgia, elevated creatine kinase, mucositis, hepatic damage, thrombocytopenia, and confusion. […] The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. […] Streptococcal TSS commonly causes acute respiratory distress syndrome (in about 55% of patients), coagulopathy, and hepatic damage and is more likely to cause high fever, malaise, tachycardia, tachypnea, and, at the site of a soft-tissue infection, severe pain. […] TSS may progress within 48 hours to syncope, tissue necrosis, shock, disseminated coagulation, multisystem organ failure, and death.

• #43 Toxic Shock Syndrome (TSS) – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/gram-positive-cocci/toxic-shock-syndrome-tss

  Toxic shock syndrome is caused by staphylococcal or streptococcal exotoxins. Manifestations include high fever, hypotension, diffuse erythematous rash, and multiple organ dysfunction, which may rapidly progress to severe and intractable shock. […] Onset of toxic shock syndrome is sudden, with […] Fever (39 to 40.5 C, which remains elevated) […] Hypotension (which can be refractory) […] A diffuse macular erythroderma […] Involvement of at least 2 other organ systems. […] Staphylococcal TSS is likely to cause vomiting, diarrhea, myalgia, elevated creatine kinase, mucositis, hepatic damage, thrombocytopenia, and confusion. […] The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. […] Streptococcal TSS commonly causes acute respiratory distress syndrome (in about 55% of patients), coagulopathy, and hepatic damage and is more likely to cause high fever, malaise, tachycardia, tachypnea, and, at the site of a soft-tissue infection, severe pain. […] TSS may progress within 48 hours to syncope, tissue necrosis, shock, disseminated coagulation, multisystem organ failure, and death.

• #44 Toxic Shock Syndrome (TSS) – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/gram-positive-cocci/toxic-shock-syndrome-tss

  Toxic shock syndrome is caused by staphylococcal or streptococcal exotoxins. Manifestations include high fever, hypotension, diffuse erythematous rash, and multiple organ dysfunction, which may rapidly progress to severe and intractable shock. […] Onset of toxic shock syndrome is sudden, with […] Fever (39 to 40.5 C, which remains elevated) […] Hypotension (which can be refractory) […] A diffuse macular erythroderma […] Involvement of at least 2 other organ systems. […] Staphylococcal TSS is likely to cause vomiting, diarrhea, myalgia, elevated creatine kinase, mucositis, hepatic damage, thrombocytopenia, and confusion. […] The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. […] Streptococcal TSS commonly causes acute respiratory distress syndrome (in about 55% of patients), coagulopathy, and hepatic damage and is more likely to cause high fever, malaise, tachycardia, tachypnea, and, at the site of a soft-tissue infection, severe pain. […] TSS may progress within 48 hours to syncope, tissue necrosis, shock, disseminated coagulation, multisystem organ failure, and death.

• #45 Toxic Shock Syndrome (TSS) – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/gram-positive-cocci/toxic-shock-syndrome-tss

  Toxic shock syndrome is caused by staphylococcal or streptococcal exotoxins. Manifestations include high fever, hypotension, diffuse erythematous rash, and multiple organ dysfunction, which may rapidly progress to severe and intractable shock. […] Onset of toxic shock syndrome is sudden, with […] Fever (39 to 40.5 C, which remains elevated) […] Hypotension (which can be refractory) […] A diffuse macular erythroderma […] Involvement of at least 2 other organ systems. […] Staphylococcal TSS is likely to cause vomiting, diarrhea, myalgia, elevated creatine kinase, mucositis, hepatic damage, thrombocytopenia, and confusion. […] The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. […] Streptococcal TSS commonly causes acute respiratory distress syndrome (in about 55% of patients), coagulopathy, and hepatic damage and is more likely to cause high fever, malaise, tachycardia, tachypnea, and, at the site of a soft-tissue infection, severe pain. […] TSS may progress within 48 hours to syncope, tissue necrosis, shock, disseminated coagulation, multisystem organ failure, and death.

• #46 Toxic Shock Syndrome (TSS) – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/gram-positive-cocci/toxic-shock-syndrome-tss

  Toxic shock syndrome is caused by staphylococcal or streptococcal exotoxins. Manifestations include high fever, hypotension, diffuse erythematous rash, and multiple organ dysfunction, which may rapidly progress to severe and intractable shock. […] Onset of toxic shock syndrome is sudden, with […] Fever (39 to 40.5 C, which remains elevated) […] Hypotension (which can be refractory) […] A diffuse macular erythroderma […] Involvement of at least 2 other organ systems. […] Staphylococcal TSS is likely to cause vomiting, diarrhea, myalgia, elevated creatine kinase, mucositis, hepatic damage, thrombocytopenia, and confusion. […] The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. […] Streptococcal TSS commonly causes acute respiratory distress syndrome (in about 55% of patients), coagulopathy, and hepatic damage and is more likely to cause high fever, malaise, tachycardia, tachypnea, and, at the site of a soft-tissue infection, severe pain. […] TSS may progress within 48 hours to syncope, tissue necrosis, shock, disseminated coagulation, multisystem organ failure, and death.

• #47 Orphanet: Streptococcal toxic-shock syndrome

  https://www.orpha.net/en/disease/detail/99918

  Streptococcal toxic-shock syndrome (streptococcal TSS) is an acute disease mediated by the production of superantigenic toxins characterized by the sudden onset of fever and other febrile symptoms, pain, multisystem organ involvement and potentially leading to coma, shock and death due to a Streptococcus pyogenes infection. […] Streptococcal TSS usually presents with a sudden onset of pain, often mimicking peritonitis or located in the extremities in previously healthy adults. General flu-like symptoms such as high fever, myalgia, nausea, diarrhea and vomiting are signs of streptococcal TSS and most patients develop hypotension soon after hospital admission. Signs of soft tissue infection can also be present manifesting with localized erythema and swelling which can lead to necrotizing fasciitis in some cases. A diffuse scarlatina-like erythema occurs in about 10% of cases. Other serious manifestations include confusion, shock, renal dysfunction, acute respiratory distress syndrome (ARDS) and coma. In some cases streptococcal TSS can be associated with acute adrenal insufficiency.

• #48 Toxic Shock Syndrome (TSS) – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/gram-positive-cocci/toxic-shock-syndrome-tss

  Toxic shock syndrome is caused by staphylococcal or streptococcal exotoxins. Manifestations include high fever, hypotension, diffuse erythematous rash, and multiple organ dysfunction, which may rapidly progress to severe and intractable shock. […] Onset of toxic shock syndrome is sudden, with […] Fever (39 to 40.5 C, which remains elevated) […] Hypotension (which can be refractory) […] A diffuse macular erythroderma […] Involvement of at least 2 other organ systems. […] Staphylococcal TSS is likely to cause vomiting, diarrhea, myalgia, elevated creatine kinase, mucositis, hepatic damage, thrombocytopenia, and confusion. […] The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. […] Streptococcal TSS commonly causes acute respiratory distress syndrome (in about 55% of patients), coagulopathy, and hepatic damage and is more likely to cause high fever, malaise, tachycardia, tachypnea, and, at the site of a soft-tissue infection, severe pain. […] TSS may progress within 48 hours to syncope, tissue necrosis, shock, disseminated coagulation, multisystem organ failure, and death.

• #49 Toxic Shock Syndrome (TSS) | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/toxic-shock-syndrome

  For streptococcal TSS: Low blood pressure, Decreased kidney function, Bleeding problems, Bruising, Red, flat rash that covers large areas of the body, Decreased liver function, Decreased urine output and sediment in urine, Difficulty breathing, Eventual sloughing of the skin (especially the palms and soles) one to two weeks after the onset of symptoms.

• #50 Toxic Shock Syndrome (TSS) – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/gram-positive-cocci/toxic-shock-syndrome-tss

  Toxic shock syndrome is caused by staphylococcal or streptococcal exotoxins. Manifestations include high fever, hypotension, diffuse erythematous rash, and multiple organ dysfunction, which may rapidly progress to severe and intractable shock. […] Onset of toxic shock syndrome is sudden, with […] Fever (39 to 40.5 C, which remains elevated) […] Hypotension (which can be refractory) […] A diffuse macular erythroderma […] Involvement of at least 2 other organ systems. […] Staphylococcal TSS is likely to cause vomiting, diarrhea, myalgia, elevated creatine kinase, mucositis, hepatic damage, thrombocytopenia, and confusion. […] The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. […] Streptococcal TSS commonly causes acute respiratory distress syndrome (in about 55% of patients), coagulopathy, and hepatic damage and is more likely to cause high fever, malaise, tachycardia, tachypnea, and, at the site of a soft-tissue infection, severe pain. […] TSS may progress within 48 hours to syncope, tissue necrosis, shock, disseminated coagulation, multisystem organ failure, and death.

• #51 Orphanet: Streptococcal toxic-shock syndrome

  https://www.orpha.net/en/disease/detail/99918

  Streptococcal toxic-shock syndrome (streptococcal TSS) is an acute disease mediated by the production of superantigenic toxins characterized by the sudden onset of fever and other febrile symptoms, pain, multisystem organ involvement and potentially leading to coma, shock and death due to a Streptococcus pyogenes infection. […] Streptococcal TSS usually presents with a sudden onset of pain, often mimicking peritonitis or located in the extremities in previously healthy adults. General flu-like symptoms such as high fever, myalgia, nausea, diarrhea and vomiting are signs of streptococcal TSS and most patients develop hypotension soon after hospital admission. Signs of soft tissue infection can also be present manifesting with localized erythema and swelling which can lead to necrotizing fasciitis in some cases. A diffuse scarlatina-like erythema occurs in about 10% of cases. Other serious manifestations include confusion, shock, renal dysfunction, acute respiratory distress syndrome (ARDS) and coma. In some cases streptococcal TSS can be associated with acute adrenal insufficiency.

• #52 Toxic Shock Syndrome: Symptoms, Treatment, and Prevention

  https://www.webmd.com/women/what-are-toxic-shock-syndrome-symptoms

  Streptococcal TSS usually happens after you have chickenpox, a skin infection, or if you have a weak immune system. The first symptom is most often severe pain that comes on suddenly. Other symptoms include: Very low blood pressure, Shock (not enough blood flow to the systems in your body), Bleeding problems, Bruising, Flat, red rash like a sunburn on most of your body, Trouble breathing. […] C. sordellii infection happens in the uterus. Its symptoms include: Nausea and vomiting, Low energy and weakness, Flu-like symptoms, Pain when you touch your abdomen, Swelling, High red and white blood cell count, Fast heart rate. […] Unlike the other most common types of TSS, such as staphylococcal TSS, C. sordellii does not usually cause a fever.

• #53 Toxic Shock Syndrome: Symptoms, Treatment, and Prevention

  https://www.webmd.com/women/what-are-toxic-shock-syndrome-symptoms

  Streptococcal TSS usually happens after you have chickenpox, a skin infection, or if you have a weak immune system. The first symptom is most often severe pain that comes on suddenly. Other symptoms include: Very low blood pressure, Shock (not enough blood flow to the systems in your body), Bleeding problems, Bruising, Flat, red rash like a sunburn on most of your body, Trouble breathing. […] C. sordellii infection happens in the uterus. Its symptoms include: Nausea and vomiting, Low energy and weakness, Flu-like symptoms, Pain when you touch your abdomen, Swelling, High red and white blood cell count, Fast heart rate. […] Unlike the other most common types of TSS, such as staphylococcal TSS, C. sordellii does not usually cause a fever.

• #54 Toxic Shock Syndrome: Symptoms, Treatment, and Prevention

  https://www.webmd.com/women/what-are-toxic-shock-syndrome-symptoms

  Streptococcal TSS usually happens after you have chickenpox, a skin infection, or if you have a weak immune system. The first symptom is most often severe pain that comes on suddenly. Other symptoms include: Very low blood pressure, Shock (not enough blood flow to the systems in your body), Bleeding problems, Bruising, Flat, red rash like a sunburn on most of your body, Trouble breathing. […] C. sordellii infection happens in the uterus. Its symptoms include: Nausea and vomiting, Low energy and weakness, Flu-like symptoms, Pain when you touch your abdomen, Swelling, High red and white blood cell count, Fast heart rate. […] Unlike the other most common types of TSS, such as staphylococcal TSS, C. sordellii does not usually cause a fever.

• #55 Toxic Shock Syndrome: Symptoms, Treatment, and Prevention

  https://www.webmd.com/women/what-are-toxic-shock-syndrome-symptoms

  Streptococcal TSS usually happens after you have chickenpox, a skin infection, or if you have a weak immune system. The first symptom is most often severe pain that comes on suddenly. Other symptoms include: Very low blood pressure, Shock (not enough blood flow to the systems in your body), Bleeding problems, Bruising, Flat, red rash like a sunburn on most of your body, Trouble breathing. […] C. sordellii infection happens in the uterus. Its symptoms include: Nausea and vomiting, Low energy and weakness, Flu-like symptoms, Pain when you touch your abdomen, Swelling, High red and white blood cell count, Fast heart rate. […] Unlike the other most common types of TSS, such as staphylococcal TSS, C. sordellii does not usually cause a fever.

• #56 Toxic Shock Syndrome: Symptoms, Treatment, and Prevention

  https://www.webmd.com/women/what-are-toxic-shock-syndrome-symptoms

  Streptococcal TSS usually happens after you have chickenpox, a skin infection, or if you have a weak immune system. The first symptom is most often severe pain that comes on suddenly. Other symptoms include: Very low blood pressure, Shock (not enough blood flow to the systems in your body), Bleeding problems, Bruising, Flat, red rash like a sunburn on most of your body, Trouble breathing. […] C. sordellii infection happens in the uterus. Its symptoms include: Nausea and vomiting, Low energy and weakness, Flu-like symptoms, Pain when you touch your abdomen, Swelling, High red and white blood cell count, Fast heart rate. […] Unlike the other most common types of TSS, such as staphylococcal TSS, C. sordellii does not usually cause a fever.

• #57 Toxic Shock Syndrome: Symptoms, Treatment, and Prevention

  https://www.webmd.com/women/what-are-toxic-shock-syndrome-symptoms

  Streptococcal TSS usually happens after you have chickenpox, a skin infection, or if you have a weak immune system. The first symptom is most often severe pain that comes on suddenly. Other symptoms include: Very low blood pressure, Shock (not enough blood flow to the systems in your body), Bleeding problems, Bruising, Flat, red rash like a sunburn on most of your body, Trouble breathing. […] C. sordellii infection happens in the uterus. Its symptoms include: Nausea and vomiting, Low energy and weakness, Flu-like symptoms, Pain when you touch your abdomen, Swelling, High red and white blood cell count, Fast heart rate. […] Unlike the other most common types of TSS, such as staphylococcal TSS, C. sordellii does not usually cause a fever.

• #58 Toxic Shock Syndrome: Symptoms, Treatment, and Prevention

  https://www.webmd.com/women/what-are-toxic-shock-syndrome-symptoms

  Streptococcal TSS usually happens after you have chickenpox, a skin infection, or if you have a weak immune system. The first symptom is most often severe pain that comes on suddenly. Other symptoms include: Very low blood pressure, Shock (not enough blood flow to the systems in your body), Bleeding problems, Bruising, Flat, red rash like a sunburn on most of your body, Trouble breathing. […] C. sordellii infection happens in the uterus. Its symptoms include: Nausea and vomiting, Low energy and weakness, Flu-like symptoms, Pain when you touch your abdomen, Swelling, High red and white blood cell count, Fast heart rate. […] Unlike the other most common types of TSS, such as staphylococcal TSS, C. sordellii does not usually cause a fever.

• #59 Toxic Shock Syndrome: Symptoms, Treatment, and Prevention

  https://www.webmd.com/women/what-are-toxic-shock-syndrome-symptoms

  Streptococcal TSS usually happens after you have chickenpox, a skin infection, or if you have a weak immune system. The first symptom is most often severe pain that comes on suddenly. Other symptoms include: Very low blood pressure, Shock (not enough blood flow to the systems in your body), Bleeding problems, Bruising, Flat, red rash like a sunburn on most of your body, Trouble breathing. […] C. sordellii infection happens in the uterus. Its symptoms include: Nausea and vomiting, Low energy and weakness, Flu-like symptoms, Pain when you touch your abdomen, Swelling, High red and white blood cell count, Fast heart rate. […] Unlike the other most common types of TSS, such as staphylococcal TSS, C. sordellii does not usually cause a fever.

• #60 Toxic shock syndrome – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/toxic-shock-syndrome/symptoms-causes/syc-20355384

  Possible signs and symptoms of toxic shock syndrome include: […] Toxic shock syndrome can progress rapidly. Complications may include: […] Call your doctor immediately if you have signs or symptoms of toxic shock syndrome. This is especially important if you’ve recently used tampons or if you have a skin or wound infection.

• #61 Toxic Shock Syndrome (TSS) – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/gram-positive-cocci/toxic-shock-syndrome-tss

  Toxic shock syndrome is caused by staphylococcal or streptococcal exotoxins. Manifestations include high fever, hypotension, diffuse erythematous rash, and multiple organ dysfunction, which may rapidly progress to severe and intractable shock. […] Onset of toxic shock syndrome is sudden, with […] Fever (39 to 40.5 C, which remains elevated) […] Hypotension (which can be refractory) […] A diffuse macular erythroderma […] Involvement of at least 2 other organ systems. […] Staphylococcal TSS is likely to cause vomiting, diarrhea, myalgia, elevated creatine kinase, mucositis, hepatic damage, thrombocytopenia, and confusion. […] The staphylococcal TSS rash is more likely to desquamate, particularly on the palms and soles, between 3 and 7 days after onset. […] Streptococcal TSS commonly causes acute respiratory distress syndrome (in about 55% of patients), coagulopathy, and hepatic damage and is more likely to cause high fever, malaise, tachycardia, tachypnea, and, at the site of a soft-tissue infection, severe pain. […] TSS may progress within 48 hours to syncope, tissue necrosis, shock, disseminated coagulation, multisystem organ failure, and death.

• #62 Toxic Shock Syndrome Clinical Presentation: History, Physical Examination, Complications

  https://emedicine.medscape.com/article/169177-clinical

  Fever is the most common presenting sign, although patients in shock may present with hypothermia. […] Patients become severely hypotensive and do not respond to intravenous fluid administration. Renal dysfunction progresses or persists in all patients, precedes shock in many patients, and is apparent early. […] Approximately 80% of patients have clinical signs of soft tissue infection (eg, localized swelling, erythema), which usually progresses to necrotizing fasciitis or myositis. […] Progression of soft tissue swelling to vesicle or bullous formation is an ominous sign and suggests streptococcal shock syndrome. […] The possibility of staphylococcal TSS should be considered in any patient who presents with a sudden onset of fever, rash, and hypotension. […] Common presenting symptoms and frequency of streptococcal TTS are as follows: Tachycardia (80%), Fever (70-81%), Hypotension (44-65%), Confusion (55%), Localized erythema (44-65%), Localized swelling and erythema (30-75%).

• #63 Toxic Shock Syndrome Symptoms & Treatment | Baptist Health

  https://www.baptisthealth.com/care-services/conditions-treatments/toxic-shock-syndrome

  Toxic shock syndrome (TSS) is a rare, but life-threatening complication caused by certain bacterial infections, such as staphylococcus aureus (staph) bacteria, group A streptococcus (strep), or clostridium sordelli. […] Symptoms may include any of the following: High fever (with quick onset) or chills, Vomiting or nausea, Diarrhea, Low blood pressure, Red rash covering most of the body (similar to a sunburn or red dots on the skin), Shedding of the skin in large patches, specifically on the palms or soles of the feet, Redness in the eyes, throat/mouth, and vagina, Fatigue, Malaise, Headache, Muscle aches, Confusion, Difficulty breathing, Bruising due to low platelet count, Low urine output, with sediment in the urine, Shock, Organ failure. […] Toxic shock syndrome can have a fast and sudden onset. Some of the most dangerous complications include: Shock, Renal failure, Death.

• #64 Toxic shock syndrome: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000653.htm

  Toxic shock syndrome is a serious and potentially life-threatening disease that involves fever, shock, and problems with several body organs. […] Symptoms include: Confusion, Diarrhea, General ill feeling, Headaches, High fever, sometimes accompanied by chills, Low blood pressure, Muscle aches, Nausea and vomiting, Organ failure (most often kidneys and liver), Redness of eyes, mouth, throat, Seizures, Widespread red rash that looks like a sunburn — skin peeling occurs 1 or 2 weeks after the rash, particularly on the palms of the hand or bottom of the feet. […] Toxic shock syndrome may be deadly in up to 50% of cases. The condition may return in those who survive. […] Toxic shock syndrome is a medical emergency. Seek medical help right away if you develop a rash, fever, and feel ill, particularly during menstruation and tampon use or if you have had recent surgery.

• #65 Toxic shock syndrome – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/toxic-shock-syndrome/diagnosis-treatment/drc-20355390

  There’s no one test for toxic shock syndrome. […] Because toxic shock syndrome can affect multiple organs, your doctor may order other tests, such as a CT scan, lumbar puncture or chest X-ray, to assess the extent of your illness. […] If you develop toxic shock syndrome, you’ll likely be hospitalized. In the hospital, you’ll: […] The toxins produced by the staph or strep bacteria and accompanying hypotension may result in kidney failure. If your kidneys fail, you may need dialysis. […] Toxic shock syndrome usually is diagnosed in an emergency setting.

• #66 Toxic Shock Syndrome (TSS) | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/toxic-shock-syndrome

  Toxic shock syndrome (TSS) is a rare but life-threatening complication of bacterial infection or colonization. TSS can affect anyone, male or female. It generally is characterized by high fever with or without chills, a sunburn-like rash, and shock (low blood pressure and/or very high heart rate). […] Symptoms usually evolve very quickly and treatment almost always requires hospitalization, intravenous antibiotics, and IV fluids, often with medicines to increase blood pressure. […] While symptoms may vary from child to child, the most common symptoms are listed below. It can look like a severe flu. Symptoms overlap between the two types of TSS, but a medical doctor can help distinguish the two infections with blood tests. […] For staphylococcal TSS: High fever, Chills, Malaise (uneasiness and despair), Headache, Fatigue, A red, flat rash that covers most of the areas of the body, Low blood pressure, Vomiting, Diarrhea, Muscle pain, Increased blood flow to mouth, eyes, and vagina, making them appear red, Decreased urine output and sediment in urine, Decreased liver function, Bruising, Disorientation and confusion, Eventual sloughing of the skin (especially the palms and soles) one to two weeks after the onset of symptoms.

• #67 Toxic Shock Syndrome – Harvard Health

  https://www.health.harvard.edu/diseases-and-conditions/toxic-shock-syndrome-a-to-z

  Toxic shock syndrome is a rare, life-threatening illness triggered by certain bacteria (group A streptococcal and Staphylococcus aureus). In toxic shock syndrome, toxins (poisons) produced by the bacteria cause a severe drop in blood pressure (hypotension) and organ failure. […] The majority (80%) of patients with group A streptococcal toxic shock syndrome have symptoms of a soft-tissue infection (pain, redness, warmth, swelling) in an area just below the skin or in a muscle. Patients with staphylococcal toxic shock syndrome may have a staphylococcal infection anywhere in the body and the site of infection may not be immediately apparent. […] Symptoms of toxic shock include: flulike symptoms such as fever, chills, muscle aches, nausea, vomiting, and diarrhea; hypotension (low blood pressure) with a weak and rapid pulse; a red rash that covers the whole body, sometimes followed by peeling skin (the rash may be difficult to see in dark-skinned individuals); decreased urine output; confusion, disorientation or other mental changes; swelling in the hands, feet and ankles; severe breathing difficulties. […] Shock and other life-threatening symptoms of toxic shock syndrome can develop suddenly. Once symptoms begin, death can follow quickly if the patient is not taken to a hospital immediately. Among hospitalized patients, the length of illness varies. Many patients require prolonged hospital treatment for kidney failure, liver failure, or for severe respiratory problems that require mechanical ventilation (in which a machine breathes for the patient).

• #68 Toxic Shock Syndrome – Causes, Symptoms, Treatment, Diagnosis – MedBroadcast.com

  https://medbroadcast.com/condition/getcondition/toxic-shock-syndrome

  TSS symptoms come on suddenly. Symptoms can include: confusion, extreme fatigue and weakness, high fever of 39C to 40.5C (102F to 105F), headache, influenza-like symptoms, low blood pressure, pain, red eyes, severe diarrhea, shortness of breath, sore throat, vomiting, widespread red rash. […] In severe cases, the symptoms get rapidly worse over the next 24 to 48 hours. Huge amounts of fluid and vital minerals leak into tissues and are lost to the vital organs. The blood supply decreases and blood pressure drops. This can produce fainting and possibly coma. Breathing problems can occur, and the blood and organs may not receive enough oxygen. After 1 to 2 weeks, the skin may start to peel, especially on the palms of the hands and soles of the feet. Also, blood may not clot properly, which increases the risk of bleeding.

• #69 Toxic shock syndrome – Wikipedia

  https://en.wikipedia.org/wiki/Toxic_shock_syndrome

  TSS resulting from infection with the bacterium Staphylococcus aureus typically manifests in otherwise healthy individuals via signs and symptoms including high fever, accompanied by low blood pressure, malaise and confusion, which can rapidly progress to stupor, coma, and multiple organ failure. […] The characteristic rash, often seen early in the course of illness, resembles a sunburn. […] In patients who survive, the rash desquamates (peels off) after 10-21 days. […] STSS caused by the bacterium Streptococcus pyogenes, or TSLS, typically presents in people with pre-existing skin infections with the bacteria. These individuals often experience severe pain at the site of the skin infection, followed by rapid progression of symptoms as described above for TSS.

• #70 Toxic Shock Syndrome (TSS): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/15437-toxic-shock-syndrome

  The onset of symptoms is usually sudden. Toxic shock syndrome tends to occur within days of the bacteria invading your bloodstream. […] Toxic shock syndrome is serious and life-threatening. Symptoms can progress quickly, and immediate treatment is necessary. Shock, organ failure, amputation of limbs and death can occur if toxic shock syndrome is left untreated. […] No, toxic shock syndrome won’t go away on its own. Prompt treatment is necessary to avoid potentially deadly complications. […] Toxic shock syndrome can lead to death in 30% to 70% of cases. Prompt diagnosis and treatment lead to the best outcomes.

• #71 Toxic Shock Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459345/

  Toxic shock syndrome (TSS) is an acute-onset illness characterized by fever, hypotension, sunburn-like rash, and end-organ damage. […] TSS typically presents with rapid onset of fever, rash, and hypotension. It may be preceded by a prodrome of fever and chills with nausea and vomiting as well as nonspecific symptoms such as myalgias, headache, or symptoms of pharyngitis (e.g., a sore throat, painful swallowing), which then progresses to sepsis and organ dysfunction. […] Early recognition and antibiotic administration are key to improving patient outcomes and reducing mortality. […] The case fatality rate of Streptococcal TSS may exceed 50%, particularly with delayed diagnosis; whereas non-streptococcal TSS is less than 3%. […] A small study in France showed that non-menstrual Toxic Shock Syndrome had a higher mortality (22%) than that of the menstrual toxic shock syndrome (0%). However, this was a small case series of 55 patients. […] Many of the complications from toxic shock syndrome are also part of the diagnostic criteria: end organ damage including renal failure, liver failure, coagulopathy, etc. In addition to these, glomerulonephritis and rheumatic fever can also occur.

• #72 Toxic Shock Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459345/

  Toxic shock syndrome (TSS) is an acute-onset illness characterized by fever, hypotension, sunburn-like rash, and end-organ damage. […] TSS typically presents with rapid onset of fever, rash, and hypotension. It may be preceded by a prodrome of fever and chills with nausea and vomiting as well as nonspecific symptoms such as myalgias, headache, or symptoms of pharyngitis (e.g., a sore throat, painful swallowing), which then progresses to sepsis and organ dysfunction. […] Early recognition and antibiotic administration are key to improving patient outcomes and reducing mortality. […] The case fatality rate of Streptococcal TSS may exceed 50%, particularly with delayed diagnosis; whereas non-streptococcal TSS is less than 3%. […] A small study in France showed that non-menstrual Toxic Shock Syndrome had a higher mortality (22%) than that of the menstrual toxic shock syndrome (0%). However, this was a small case series of 55 patients. […] Many of the complications from toxic shock syndrome are also part of the diagnostic criteria: end organ damage including renal failure, liver failure, coagulopathy, etc. In addition to these, glomerulonephritis and rheumatic fever can also occur.

• #73 Orphanet: Streptococcal toxic-shock syndrome

  https://www.orpha.net/en/disease/detail/99918

  Streptococcal toxic-shock syndrome (streptococcal TSS) is an acute disease mediated by the production of superantigenic toxins characterized by the sudden onset of fever and other febrile symptoms, pain, multisystem organ involvement and potentially leading to coma, shock and death due to a Streptococcus pyogenes infection. […] Streptococcal TSS usually presents with a sudden onset of pain, often mimicking peritonitis or located in the extremities in previously healthy adults. General flu-like symptoms such as high fever, myalgia, nausea, diarrhea and vomiting are signs of streptococcal TSS and most patients develop hypotension soon after hospital admission. Signs of soft tissue infection can also be present manifesting with localized erythema and swelling which can lead to necrotizing fasciitis in some cases. A diffuse scarlatina-like erythema occurs in about 10% of cases. Other serious manifestations include confusion, shock, renal dysfunction, acute respiratory distress syndrome (ARDS) and coma. In some cases streptococcal TSS can be associated with acute adrenal insufficiency.

• #74 Toxic shock syndrome: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000653.htm

  Toxic shock syndrome is a serious and potentially life-threatening disease that involves fever, shock, and problems with several body organs. […] Symptoms include: Confusion, Diarrhea, General ill feeling, Headaches, High fever, sometimes accompanied by chills, Low blood pressure, Muscle aches, Nausea and vomiting, Organ failure (most often kidneys and liver), Redness of eyes, mouth, throat, Seizures, Widespread red rash that looks like a sunburn — skin peeling occurs 1 or 2 weeks after the rash, particularly on the palms of the hand or bottom of the feet. […] Toxic shock syndrome may be deadly in up to 50% of cases. The condition may return in those who survive. […] Toxic shock syndrome is a medical emergency. Seek medical help right away if you develop a rash, fever, and feel ill, particularly during menstruation and tampon use or if you have had recent surgery.

• #75 Toxic Shock Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459345/

  Toxic shock syndrome (TSS) is an acute-onset illness characterized by fever, hypotension, sunburn-like rash, and end-organ damage. […] TSS typically presents with rapid onset of fever, rash, and hypotension. It may be preceded by a prodrome of fever and chills with nausea and vomiting as well as nonspecific symptoms such as myalgias, headache, or symptoms of pharyngitis (e.g., a sore throat, painful swallowing), which then progresses to sepsis and organ dysfunction. […] Early recognition and antibiotic administration are key to improving patient outcomes and reducing mortality. […] The case fatality rate of Streptococcal TSS may exceed 50%, particularly with delayed diagnosis; whereas non-streptococcal TSS is less than 3%. […] A small study in France showed that non-menstrual Toxic Shock Syndrome had a higher mortality (22%) than that of the menstrual toxic shock syndrome (0%). However, this was a small case series of 55 patients. […] Many of the complications from toxic shock syndrome are also part of the diagnostic criteria: end organ damage including renal failure, liver failure, coagulopathy, etc. In addition to these, glomerulonephritis and rheumatic fever can also occur.

• #76 Orphanet: Streptococcal toxic-shock syndrome

  https://www.orpha.net/en/disease/detail/99918

  The onset of streptococcal TSS is sudden and requires immediate medical treatment in an intensive care setting. Treatment involves antibiotics (beta-lactam antibiotics and clindamycin) along with supportive therapy (fluid resuscitation, inotropes and vassopressors) and intravenous immunoglobins that block superantigens. Corticosteroids and recombinant activated protein C (derotrecogin-alpha) can also be helpful in some cases. Dialysis may be necessary for those with renal dysfunction and oxygen supplementation along with mechanical ventilation is required for patients with ARDS. Suspected necrotizing fasciitis may require debridement. […] The prognosis varies, with streptococcal TSS having a mortality rate of 30-80% in adults and 5-8% in children.

• #77 Orphanet: Streptococcal toxic-shock syndrome

  https://www.orpha.net/en/disease/detail/99918

  The onset of streptococcal TSS is sudden and requires immediate medical treatment in an intensive care setting. Treatment involves antibiotics (beta-lactam antibiotics and clindamycin) along with supportive therapy (fluid resuscitation, inotropes and vassopressors) and intravenous immunoglobins that block superantigens. Corticosteroids and recombinant activated protein C (derotrecogin-alpha) can also be helpful in some cases. Dialysis may be necessary for those with renal dysfunction and oxygen supplementation along with mechanical ventilation is required for patients with ARDS. Suspected necrotizing fasciitis may require debridement. […] The prognosis varies, with streptococcal TSS having a mortality rate of 30-80% in adults and 5-8% in children.

• #78 Toxic Shock Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459345/

  Toxic shock syndrome (TSS) is an acute-onset illness characterized by fever, hypotension, sunburn-like rash, and end-organ damage. […] TSS typically presents with rapid onset of fever, rash, and hypotension. It may be preceded by a prodrome of fever and chills with nausea and vomiting as well as nonspecific symptoms such as myalgias, headache, or symptoms of pharyngitis (e.g., a sore throat, painful swallowing), which then progresses to sepsis and organ dysfunction. […] Early recognition and antibiotic administration are key to improving patient outcomes and reducing mortality. […] The case fatality rate of Streptococcal TSS may exceed 50%, particularly with delayed diagnosis; whereas non-streptococcal TSS is less than 3%. […] A small study in France showed that non-menstrual Toxic Shock Syndrome had a higher mortality (22%) than that of the menstrual toxic shock syndrome (0%). However, this was a small case series of 55 patients. […] Many of the complications from toxic shock syndrome are also part of the diagnostic criteria: end organ damage including renal failure, liver failure, coagulopathy, etc. In addition to these, glomerulonephritis and rheumatic fever can also occur.

• #79 Toxic Shock Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459345/

  Toxic shock syndrome (TSS) is an acute-onset illness characterized by fever, hypotension, sunburn-like rash, and end-organ damage. […] TSS typically presents with rapid onset of fever, rash, and hypotension. It may be preceded by a prodrome of fever and chills with nausea and vomiting as well as nonspecific symptoms such as myalgias, headache, or symptoms of pharyngitis (e.g., a sore throat, painful swallowing), which then progresses to sepsis and organ dysfunction. […] Early recognition and antibiotic administration are key to improving patient outcomes and reducing mortality. […] The case fatality rate of Streptococcal TSS may exceed 50%, particularly with delayed diagnosis; whereas non-streptococcal TSS is less than 3%. […] A small study in France showed that non-menstrual Toxic Shock Syndrome had a higher mortality (22%) than that of the menstrual toxic shock syndrome (0%). However, this was a small case series of 55 patients. […] Many of the complications from toxic shock syndrome are also part of the diagnostic criteria: end organ damage including renal failure, liver failure, coagulopathy, etc. In addition to these, glomerulonephritis and rheumatic fever can also occur.

• #80 Toxic Shock Syndrome (TSS): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/15437-toxic-shock-syndrome

  The onset of symptoms is usually sudden. Toxic shock syndrome tends to occur within days of the bacteria invading your bloodstream. […] Toxic shock syndrome is serious and life-threatening. Symptoms can progress quickly, and immediate treatment is necessary. Shock, organ failure, amputation of limbs and death can occur if toxic shock syndrome is left untreated. […] No, toxic shock syndrome won’t go away on its own. Prompt treatment is necessary to avoid potentially deadly complications. […] Toxic shock syndrome can lead to death in 30% to 70% of cases. Prompt diagnosis and treatment lead to the best outcomes.

• #81 Toxic shock syndrome (TSS) | Healthify

  https://healthify.nz/health-a-z/t/toxic-shock-syndrome-tss/

  Toxic shock syndrome (TSS) is an uncommon but life-threatening condition caused by poisons from certain bacterial infections getting into your blood. […] Symptoms come on quickly and get worse quickly. They include fever, chills, body pain, vomiting and diarrhoea, low blood pressure and a skin rash over most or all of your body. […] The symptoms appear suddenly and get worse quickly. If you don’t get treatment quickly you could develop severe body organ damage or die. […] The symptoms of TSS usually start suddenly and quickly get worse, especially if treatment isn’t started as soon as possible. […] Get medical help straight away if you have the symptoms below, because TSS can quickly result in the failure of important body organs, such as your kidneys, lungs and heart. […] TSS gets worse very quickly and can be fatal if it’s not treated quickly. If it’s diagnosed and treated early, most people make a full recovery. […] If toxic shock syndrome isn’t treated quickly you may develop complications such as heart and lung problems, kidney failure and blood clotting problems. About 5 to 15% of people who get toxic shock syndrome (TSS) die. TSS caused by Streptococcus pyogenes is more likely to be fatal.

• #82 Toxic shock syndrome: Symptoms, causes, and diagnosis

  https://www.medicalnewstoday.com/articles/175736

  Toxic shock syndrome is a potentially fatal condition that starts with a staphylococcal or streptococcal strain of bacteria. […] Signs and symptoms of TSS develop suddenly and progress quickly. The first indication is normally a sudden, high fever. […] The condition can progress to kidney failure, shock, and death within 48 hours. […] The risk of developing TSS is very low, but there appears to be a significant link between tampon use and absorbency and TSS risk. […] The chance of staphylococcal TSS being fatal is less than 3 percent, but recurrence is common, because having it does not cause the person to develop an immunity. […] In streptococcal TSS, mortality is between 20 percent and 60 percent, even with aggressive treatment.

• #83 Toxic shock syndrome // Middlesex Health

  https://middlesexhealth.org/learning-center/diseases-and-conditions/toxic-shock-syndrome

  Possible signs and symptoms of toxic shock syndrome include: A sudden high fever […] Toxic shock syndrome can progress rapidly. Complications may include: Shock […] Toxic shock syndrome can recur. People who’ve had it once can get it again.

• #84 Toxic shock syndrome – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/toxic-shock-syndrome/symptoms-causes/syc-20355384

  Possible signs and symptoms of toxic shock syndrome include: […] Toxic shock syndrome can progress rapidly. Complications may include: […] Call your doctor immediately if you have signs or symptoms of toxic shock syndrome. This is especially important if you’ve recently used tampons or if you have a skin or wound infection.

• #85 Toxic Shock Syndrome – Harvard Health

  https://www.health.harvard.edu/a_to_z/toxic-shock-syndrome-a-to-z

  Shock and other life-threatening symptoms of toxic shock syndrome can develop suddenly. Once symptoms begin, death can follow quickly if the patient is not taken to a hospital immediately. Among hospitalized patients, the length of illness varies. Many patients require prolonged hospital treatment for kidney failure, liver failure, or for severe respiratory problems that require mechanical ventilation (in which a machine breathes for the patient). […] Toxic shock syndrome is a medical emergency. Call your doctor immediately whenever someone develops the symptoms listed above. Also, contact your doctor if a wound, puncture, or bruise becomes red, warm, swollen, or painful.

• #86 Toxic Shock Syndrome (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/toxic-shock.html

  Toxic shock syndrome starts suddenly, often with a high fever (temperature at least 102F [38.8C]). […] Other signs include vomiting, confusion, weakness, tiredness, peeing less than usual, and being thirsty. A person also might have bloodshot eyes and an unusual redness under the eyelids or inside the mouth (and in the vagina in females). The area around an infected wound can become swollen, red, and tender. […] Symptoms of toxic shock syndrome come on suddenly. Call your doctor right away if your child gets a sudden high fever, feels faint, or has other signs of TSS.

• #87 Toxic Shock Syndrome (for Teens) | Nemours KidsHealth

  https://kidshealth.org/en/teens/tss.html

  Toxic shock syndrome starts suddenly, often with a high fever (temperature at least 102F [38.8C]). […] Other signs include vomiting, confusion, weakness, tiredness, peeing less than usual, and being thirsty. […] A person also might have bloodshot eyes and an unusual redness under the eyelids or inside the mouth (and in the vagina in females). The area around an infected wound can become swollen, red, and tender. […] Symptoms of toxic shock syndrome come on suddenly. Call your doctor right away if you get a sudden high fever, feel faint, or have any other signs of TSS.

• #88 Toxic shock syndrome

  https://www.nhs.uk/conditions/toxic-shock-syndrome/

  Toxic shock syndrome (TSS) can come on quickly. […] Symptoms include: a high temperature, muscle aches, a raised skin rash that feels like sandpaper, flu-like symptoms. […] You think you might have toxic shock syndrome and you have any of these symptoms: a high temperature, feeling shivery, with muscle aches, vomiting and diarrhoea, severe pain in your arms or legs, or all over your body, a rash that feels rough like sandpaper the rash may look red, which can be harder to see on brown or black skin, the palms of your hands, soles of your feet, tongue and the whites of your eyes turn bright red, swollen or peeling skin, feeling sick, dizzy or confused.

• #89 Toxic shock syndrome

  https://www.nhs.uk/conditions/toxic-shock-syndrome/

  Toxic shock syndrome (TSS) can come on quickly. […] Symptoms include: a high temperature, muscle aches, a raised skin rash that feels like sandpaper, flu-like symptoms. […] You think you might have toxic shock syndrome and you have any of these symptoms: a high temperature, feeling shivery, with muscle aches, vomiting and diarrhoea, severe pain in your arms or legs, or all over your body, a rash that feels rough like sandpaper the rash may look red, which can be harder to see on brown or black skin, the palms of your hands, soles of your feet, tongue and the whites of your eyes turn bright red, swollen or peeling skin, feeling sick, dizzy or confused.

• #90 Toxic Shock Syndrome (TSS)

  https://healthlibrary.uwmedicine.org/Conditions/Pregnancy/85,P00653

  Symptoms of TSS involve many systems. They may look like other infections. Each person is different, but symptoms of TSS can start quickly and include: […] Early symptoms are similar to other infections. But they can progress quickly to become life-threatening. […] TSS may start like other infections. But it can quickly progress to a life-threatening disease. If a mild illness quickly becomes severe with whole-body symptoms, seek care right away.

• #91 Toxic Shock Syndrome (TSS) – Basics & Causes

  https://www.webmd.com/women/understanding-toxic-shock-syndrome-basics

  When it starts, TSS causes the same symptoms as a lot of other less serious illnesses. They come on suddenly and include: A high fever and chills, Muscle aches, Vomiting and diarrhea, Headache, Sore throat. […] Symptoms get worse fast, and you can also have: Low blood pressure, A rash that looks like a sunburn, especially on your palms and bottoms of your feet, Red eyes, mouth, and throat, Confusion, Seizures. […] After about a week, the rash from TSS can cause your skin to peel in large sheets. […] You may feel like you have the flu at first. But you’ll quickly feel much sicker as the toxins from the infection start to damage your organs. Pay special attention to symptoms like a sudden high fever and vomiting if you’re on your period or if you have an open wound or a skin infection. If you’re using a tampon, menstrual sponge, diaphragm, or cervical cap when you get sick, take it out right away, even before you call the doctor. […] TSS starts out with mild flu-like symptoms that get worse fast. You should suspect it if you suddenly feel very sick all over your body, especially if you’ve been using tampons or have an infected cut or burn.

• #92 What Everyone Should Know about Toxic Shock Syndrome (TSS)

  https://tampax.com/en-us/period-health/toxic-shock-syndrome-causes-treatment/

  TSS can feel a lot like the flu, and symptoms can vary from person to person, but most commonly, the symptoms of TSS are: […] High fever (over 102 F or 38.9 C) […] Body or joint aches […] Nausea and/or vomiting […] Diarrhea […] Dizziness or fainting or confusion […] Sometimes there is a red rash […] If you are using a tampon, and feel very ill with some of the symptoms above, its important to remove your tampon right away, get immediate medical attention, and tell the person youre with or the healthcare provider youre worried about Toxic Shock Syndrome.

• #93 Toxic shock syndrome | HealthLink BC

  https://www.healthlinkbc.ca/healthlinkbc-files/toxic-shock-syndrome

  Symptoms of TSS include flu-like symptoms such as fever, headache and muscle soreness. These symptoms will develop quickly and are severe. Other symptoms may include pain at the site of a wound, vomiting and diarrhea, signs of shock including low blood pressure and light-headedness, shortness of breath and a sunburn-like rash. […] In general, TSS symptoms can develop as soon as 12 hours after a surgical procedure. Symptoms usually develop in 3 to 5 days in individuals who are menstruating and using tampons or menstrual cups. […] If you experience the above symptoms after using tampons, a menstrual cup or after a surgery or skin injury, contact your health care provider immediately.

• #94 Toxic shock syndrome | HealthLink BC

  https://www.healthlinkbc.ca/healthlinkbc-files/toxic-shock-syndrome

  Symptoms of TSS include flu-like symptoms such as fever, headache and muscle soreness. These symptoms will develop quickly and are severe. Other symptoms may include pain at the site of a wound, vomiting and diarrhea, signs of shock including low blood pressure and light-headedness, shortness of breath and a sunburn-like rash. […] In general, TSS symptoms can develop as soon as 12 hours after a surgical procedure. Symptoms usually develop in 3 to 5 days in individuals who are menstruating and using tampons or menstrual cups. […] If you experience the above symptoms after using tampons, a menstrual cup or after a surgery or skin injury, contact your health care provider immediately.

• #95 Toxic Shock Syndrome (TSS): Signs and Symptoms

  https://www.health.com/toxic-shock-syndrome-symptoms-8353272

  Toxic shock syndrome (TSS) is a rare but serious, life-threatening condition that occurs when bacteria like Staphylococcus aureus (known as staph) or Streptococcus pyogenes (known as strep A) release harmful toxins into the blood. If you develop this infection, it’s common to experience flu-like symptoms like high fever, sore throat, and fatigue. But without treatment, symptoms can worsen and cause seizures and organ failure. […] TSS affects less than 1% of people in the U.S. each year, but if you or a loved one experiences symptoms of the condition, it’s necessary to see a healthcare provider urgently to prevent serious complications. […] Early symptoms of TSS may include: Fever higher than 102 degrees Fahrenheit or 38.9 degrees Celcius, Fatigue, Muscle aches or weakness, Sore throat or cough, Headache, Runny nose, Nausea or vomiting, Diarrhea.

• #96 Toxic Shock Syndrome (TSS): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/15437-toxic-shock-syndrome

  Toxic shock syndrome (TSS) is a rare but serious condition caused by certain strains of bacteria. It causes toxins to spread into the bloodstream, causing severe organ damage or death. Knowing the signs of TSS and seeking prompt treatment results in the best outcomes. […] The symptoms of TSS happen suddenly and worsen quickly. However, most people recover if TSS is diagnosed and treated quickly. […] Symptoms of toxic shock syndrome may vary depending on the type of bacteria producing the toxins. They may include: Sudden high fever, chills, body aches and other flu-like symptoms. Nausea or vomiting. Watery diarrhea. Rash resembling a bad sunburn or red dots on your skin. Dizziness, lightheadedness or fainting. Low blood pressure (hypotension). Redness in your eyes (conjunctivitis) and throat. Peeling of the skin on the soles of your feet or palms of your hands.

• #97 Toxic shock syndrome: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000653.htm

  Toxic shock syndrome is a serious and potentially life-threatening disease that involves fever, shock, and problems with several body organs. […] Symptoms include: Confusion, Diarrhea, General ill feeling, Headaches, High fever, sometimes accompanied by chills, Low blood pressure, Muscle aches, Nausea and vomiting, Organ failure (most often kidneys and liver), Redness of eyes, mouth, throat, Seizures, Widespread red rash that looks like a sunburn — skin peeling occurs 1 or 2 weeks after the rash, particularly on the palms of the hand or bottom of the feet. […] Toxic shock syndrome may be deadly in up to 50% of cases. The condition may return in those who survive. […] Toxic shock syndrome is a medical emergency. Seek medical help right away if you develop a rash, fever, and feel ill, particularly during menstruation and tampon use or if you have had recent surgery.

• #98 About Streptococcal Toxic Shock Syndrome | Group A Strep | CDC

  https://www.cdc.gov/group-a-strep/about/streptococcal-toxic-shock-syndrome.html

  Streptococcal toxic shock syndrome (STSS) is a rare, but serious bacterial infection. STSS can develop very quickly into a life-threatening emergency. People with STSS need immediate care in a hospital and antibiotics. First symptoms of STSS often include: Fever and chills, Muscle aches, Nausea and vomiting. After the first symptoms start, it usually only takes about 24 to 48 hours for low blood pressure to develop. Once this happens, STSS quickly gets much more serious: Hypotension (low blood pressure), Organ failure (other signs that organs are not working), Tachycardia (faster than normal heart rate), Tachypnea (rapid breathing). STSS often results in complications from organs shutting down and the body going into shock. Even with treatment, STSS can be deadly. Out of 10 people with STSS, as many as 3 people will die from the infection. Healthcare providers diagnose STSS when the patient has all the following: A group A strep infection, Low blood pressure, Problems with 2 or more organs. People with STSS need care in a hospital. They often need fluids given through a vein and other treatments to help treat shock and organ failure. Many people with STSS also need surgery to remove infected tissue.

• #99 Toxic Shock Syndrome (TSS): Signs and Symptoms

  https://www.health.com/toxic-shock-syndrome-symptoms-8353272

  When toxins from TSS widen the blood vessels in the skin, a flat, red, sunburn-like rash can appear. […] Aside from a skin rash, TSS can cause also cause redness in the whites of the eyes, mouth, throat, or vagina. […] Confusion occurs when you don’t know where you are, who you are, or what time it is. […] Seizures are sudden, uncontrolled disturbances that can affect the chemicals in your brain. […] Organ dysfunction is a severe and potentially life-threatening complication of TSS. […] If your flu-like symptoms persist and you begin to notice symptoms like a rash, redness, low blood pressure, confusion, and seizures, it’s necessary to get the medical care you need immediately. […] TSS typically requires hospitalization in an intensive care unit (ICU) and treatment such as intravenous (IV) antibiotics and fluids.

• #100 Toxic Shock Syndrome (TSS) | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/toxic-shock-syndrome

  Toxic shock syndrome (TSS) is a rare but life-threatening complication of bacterial infection or colonization. TSS can affect anyone, male or female. It generally is characterized by high fever with or without chills, a sunburn-like rash, and shock (low blood pressure and/or very high heart rate). […] Symptoms usually evolve very quickly and treatment almost always requires hospitalization, intravenous antibiotics, and IV fluids, often with medicines to increase blood pressure. […] While symptoms may vary from child to child, the most common symptoms are listed below. It can look like a severe flu. Symptoms overlap between the two types of TSS, but a medical doctor can help distinguish the two infections with blood tests. […] For staphylococcal TSS: High fever, Chills, Malaise (uneasiness and despair), Headache, Fatigue, A red, flat rash that covers most of the areas of the body, Low blood pressure, Vomiting, Diarrhea, Muscle pain, Increased blood flow to mouth, eyes, and vagina, making them appear red, Decreased urine output and sediment in urine, Decreased liver function, Bruising, Disorientation and confusion, Eventual sloughing of the skin (especially the palms and soles) one to two weeks after the onset of symptoms.

• #101 Toxic shock syndrome – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/toxic-shock-syndrome/diagnosis-treatment/drc-20355390

  There’s no one test for toxic shock syndrome. […] Because toxic shock syndrome can affect multiple organs, your doctor may order other tests, such as a CT scan, lumbar puncture or chest X-ray, to assess the extent of your illness. […] If you develop toxic shock syndrome, you’ll likely be hospitalized. In the hospital, you’ll: […] The toxins produced by the staph or strep bacteria and accompanying hypotension may result in kidney failure. If your kidneys fail, you may need dialysis. […] Toxic shock syndrome usually is diagnosed in an emergency setting.

• #102 Toxic Shock Syndrome (TSS): Causes, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/15437-toxic-shock-syndrome

  The onset of symptoms is usually sudden. Toxic shock syndrome tends to occur within days of the bacteria invading your bloodstream. […] Toxic shock syndrome is serious and life-threatening. Symptoms can progress quickly, and immediate treatment is necessary. Shock, organ failure, amputation of limbs and death can occur if toxic shock syndrome is left untreated. […] No, toxic shock syndrome won’t go away on its own. Prompt treatment is necessary to avoid potentially deadly complications. […] Toxic shock syndrome can lead to death in 30% to 70% of cases. Prompt diagnosis and treatment lead to the best outcomes.

• #103 Toxic Shock Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459345/

  Toxic shock syndrome (TSS) is an acute-onset illness characterized by fever, hypotension, sunburn-like rash, and end-organ damage. […] TSS typically presents with rapid onset of fever, rash, and hypotension. It may be preceded by a prodrome of fever and chills with nausea and vomiting as well as nonspecific symptoms such as myalgias, headache, or symptoms of pharyngitis (e.g., a sore throat, painful swallowing), which then progresses to sepsis and organ dysfunction. […] Early recognition and antibiotic administration are key to improving patient outcomes and reducing mortality. […] The case fatality rate of Streptococcal TSS may exceed 50%, particularly with delayed diagnosis; whereas non-streptococcal TSS is less than 3%. […] A small study in France showed that non-menstrual Toxic Shock Syndrome had a higher mortality (22%) than that of the menstrual toxic shock syndrome (0%). However, this was a small case series of 55 patients. […] Many of the complications from toxic shock syndrome are also part of the diagnostic criteria: end organ damage including renal failure, liver failure, coagulopathy, etc. In addition to these, glomerulonephritis and rheumatic fever can also occur.

• #104 Toxic Shock Syndrome – Harvard Health

  https://www.health.harvard.edu/a_to_z/toxic-shock-syndrome-a-to-z

  Shock and other life-threatening symptoms of toxic shock syndrome can develop suddenly. Once symptoms begin, death can follow quickly if the patient is not taken to a hospital immediately. Among hospitalized patients, the length of illness varies. Many patients require prolonged hospital treatment for kidney failure, liver failure, or for severe respiratory problems that require mechanical ventilation (in which a machine breathes for the patient). […] Toxic shock syndrome is a medical emergency. Call your doctor immediately whenever someone develops the symptoms listed above. Also, contact your doctor if a wound, puncture, or bruise becomes red, warm, swollen, or painful.

• #105 Toxic shock syndrome – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/toxic-shock-syndrome/symptoms-causes/syc-20355384

  Possible signs and symptoms of toxic shock syndrome include: […] Toxic shock syndrome can progress rapidly. Complications may include: […] Call your doctor immediately if you have signs or symptoms of toxic shock syndrome. This is especially important if you’ve recently used tampons or if you have a skin or wound infection.

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