Materiały źródłowe

• #1 Statistics and Facts – Brain Aneurysm Foundation

  https://www.bafound.org/statistics-and-facts/

  An estimated 6.8 million people in the United States have an unruptured brain aneurysm, or 1 in 50 people. […] The annual rate of rupture is approximately 8 – 10 per 100,000 people. […] About 30,000 people in the United States suffer a brain aneurysm rupture each year. A brain aneurysm ruptures every 18 minutes. […] There are almost 500,000 deaths worldwide each year caused by brain aneurysms, and half the victims are younger than 50. […] Brain aneurysms are most prevalent in people ages 35 to 60, but can occur in children as well. Most aneurysms develop after the age of 40. […] Women are more likely than men to have a brain aneurysm (3:2 ratio). […] Women, particularly those over the age of 55, have a higher risk of brain aneurysm rupture than men (about 1.5 times the risk). […] African-Americans and Hispanics are about twice as likely to have a brain aneurysm rupture compared to caucasians.

• #2 An Analysis of the Incidence and Cost of Intracranial Aneurysm and Subarachnoid Haemorrhage Treatment between 2013 and 2021

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10001767/

  The incidence of unruptured intracranial aneurysms (UIAs) amounts to 3.2% among adults. […] The annual risk of aneurysm rupture is 2-10% and it results in subarachnoid haemorrhage (SAH). […] The overall incidence of SAH is 9.1 per 100,000 person-years in most regions of the world, yielding approximately 36,000 SAH cases per year in Europe. […] The incidence of SAH increases with the age of the patient, the mean age of the first SAH incidence in a lifetime is 52 years. […] The changes that were observed in the rate of change of the value of services prescribed per patient or per hospitalisation were highly consistent. […] The overall number of patients hospitalised with diagnosis of UIA or SAH is not decreasing in subsequent years of observation. […] The recorded changes in the dynamics of the value of medical services per patient or per hospitalisation largely coincided.

• #3 Cerebral Aneurysm – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507902/

  Cerebral aneurysms are defined as dilations that occur at weak points along the arterial circulation within the brain. The majority of cerebral aneurysms are silent and may be found incidentally on neuroimaging or upon autopsy. Approximately 85% of aneurysms are located in the anterior circulation, predominately at junctions or bifurcations along the circle of Willis. Subarachnoid hemorrhage (SAH) usually occurs with rupture and is associated with a high rate of morbidity and mortality. […] The worldwide prevalence of cerebral aneurysms is approximately 3.2%, with a mean age of 50 and an overall 1:1 gender ratio. This ratio changes significantly after age 50, with an increasing female predominance approaching 2:1, thought to be due to decreased circulating estrogen causing a reduction in the collagen content of the vascular tissue. The rate of rupture causing SAH is about 10 per 100,000. This is higher in certain populations such as the Finnish and Japanese. However, this is not due to a higher prevalence of aneurysms in these populations. The overall mortality due to aneurysmal SAH is considered to be 0.4 to 0.6% of all-cause deaths, with an approximate 20% mortality and an additional 30 to 40% morbidity in patients with known rupture.

• #4 Screening for intracranial aneurysm – UpToDate

  https://www.uptodate.com/contents/screening-for-intracranial-aneurysm

  Screening for intracranial aneurysm […] Most SAHs are caused by ruptured saccular aneurysms. Recommendations for screening for aneurysms and methods of screening are discussed here. The epidemiology and pathogenesis of intracranial aneurysms, management of unruptured aneurysms, and screening for new aneurysms after treatment for SAH are discussed separately. […] Widespread screening for cerebral aneurysm is not warranted. This was also the conclusion in guidelines published by the American Stroke Association. […] The prevalence of intracranial saccular aneurysms by radiographic and autopsy series is approximately 0.4 to 6.0 percent, or between 1 and 18 million people in the United States. In adult patients without risk factors, the best estimate is that approximately 2 percent harbor asymptomatic cerebral aneurysms. Aneurysmal subarachnoid hemorrhage (SAH) occurs at an estimated rate of 6 to 16 per 100,000 population. In North America, this translates into approximately 30,000 affected persons per year. Thus, most aneurysms do not rupture.

• #5 Intracranial Aneurysms: Current Evidence and Clinical Practice | AAFP

  https://www.aafp.org/pubs/afp/issues/2002/0815/p601.html

  Unruptured intracranial aneurysms occur in up to 6 percent of the general population. […] A recent systematic review of studies involving more than 56,000 patients found that unruptured intracranial aneurysms occur in 3.6 to 6 percent of the general population. […] The incidence of intracranial aneurysms is between 8 and 9 percent in persons with two or more relatives who have had a subarachnoid hemorrhage or an aneurysm. […] Recent data have shown that age over 50 years, female gender, and current cigarette smoking are risk factors for intracranial aneurysm. […] Since 1984, cocaine use has been linked to the formation and rupture of aneurysms. […] The findings of the International Study of Unruptured Intracranial Aneurysms (ISUIA) were published in 1998. […] The ISUIA data suggest that aneurysms with a diameter of 10 mm or more are at critical risk for rupture.

• #6 Cerebral Aneurysm – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507902/

  Cerebral aneurysms are defined as dilations that occur at weak points along the arterial circulation within the brain. The majority of cerebral aneurysms are silent and may be found incidentally on neuroimaging or upon autopsy. Approximately 85% of aneurysms are located in the anterior circulation, predominately at junctions or bifurcations along the circle of Willis. Subarachnoid hemorrhage (SAH) usually occurs with rupture and is associated with a high rate of morbidity and mortality. […] The worldwide prevalence of cerebral aneurysms is approximately 3.2%, with a mean age of 50 and an overall 1:1 gender ratio. This ratio changes significantly after age 50, with an increasing female predominance approaching 2:1, thought to be due to decreased circulating estrogen causing a reduction in the collagen content of the vascular tissue. The rate of rupture causing SAH is about 10 per 100,000. This is higher in certain populations such as the Finnish and Japanese. However, this is not due to a higher prevalence of aneurysms in these populations. The overall mortality due to aneurysmal SAH is considered to be 0.4 to 0.6% of all-cause deaths, with an approximate 20% mortality and an additional 30 to 40% morbidity in patients with known rupture.

• #7 Statistics and Facts – Brain Aneurysm Foundation

  https://www.bafound.org/statistics-and-facts/

  An estimated 6.8 million people in the United States have an unruptured brain aneurysm, or 1 in 50 people. […] The annual rate of rupture is approximately 8 – 10 per 100,000 people. […] About 30,000 people in the United States suffer a brain aneurysm rupture each year. A brain aneurysm ruptures every 18 minutes. […] There are almost 500,000 deaths worldwide each year caused by brain aneurysms, and half the victims are younger than 50. […] Brain aneurysms are most prevalent in people ages 35 to 60, but can occur in children as well. Most aneurysms develop after the age of 40. […] Women are more likely than men to have a brain aneurysm (3:2 ratio). […] Women, particularly those over the age of 55, have a higher risk of brain aneurysm rupture than men (about 1.5 times the risk). […] African-Americans and Hispanics are about twice as likely to have a brain aneurysm rupture compared to caucasians.

• #8 Cerebral Aneurysm: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1161518-overview

  Cerebral aneurysms affect equal numbers of women and men younger than 40 years, although women are affected more frequently in older age groups. Overall, the female-to-male ratio has been estimated at 1.6:1. […] Saccular aneurysms are most common in the anterior communicating artery (ACoA) or anterior cerebral artery (ACA) in men, whereas the junction of the ICA with the posterior communicating artery (PCoA) is the most common site for saccular aneurysms in women. […] The prognosis of aneurysmal SAH worsens with increasing age.

• #9 Cerebral Aneurysm – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507902/

  Cerebral aneurysms are defined as dilations that occur at weak points along the arterial circulation within the brain. The majority of cerebral aneurysms are silent and may be found incidentally on neuroimaging or upon autopsy. Approximately 85% of aneurysms are located in the anterior circulation, predominately at junctions or bifurcations along the circle of Willis. Subarachnoid hemorrhage (SAH) usually occurs with rupture and is associated with a high rate of morbidity and mortality. […] The worldwide prevalence of cerebral aneurysms is approximately 3.2%, with a mean age of 50 and an overall 1:1 gender ratio. This ratio changes significantly after age 50, with an increasing female predominance approaching 2:1, thought to be due to decreased circulating estrogen causing a reduction in the collagen content of the vascular tissue. The rate of rupture causing SAH is about 10 per 100,000. This is higher in certain populations such as the Finnish and Japanese. However, this is not due to a higher prevalence of aneurysms in these populations. The overall mortality due to aneurysmal SAH is considered to be 0.4 to 0.6% of all-cause deaths, with an approximate 20% mortality and an additional 30 to 40% morbidity in patients with known rupture.

• #10 Cerebral Aneurysm Market Size, Trends & Report, 2034

  https://www.imarcgroup.com/cerebral-aneurys-market

  The cerebral aneurysm market has been comprehensively analyzed in IMARC’s new report titled „Cerebral Aneurysm Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034”. […] The global prevalence of cerebral aneurysms is around 3.2%, with a mean age of 50 and a 1:1 gender ratio. […] This ratio shifts considerably beyond age 50, with female preponderance nearing 2:1, which is assumed to be owing to decreasing circulating estrogen, which causes a decrease in the collagen composition of vascular tissue. […] Ruptured aneurysms are less common, occurring in approximately ten per 100,000 instances. […] Most aneurysms form after the age of 40; however, they can also occur in children. […] African-Americans and Hispanics have twice the risk of having a ruptured cerebral aneurysm as Caucasians.

• #11 Statistics and Facts – Brain Aneurysm Foundation

  https://www.bafound.org/statistics-and-facts/

  An estimated 6.8 million people in the United States have an unruptured brain aneurysm, or 1 in 50 people. […] The annual rate of rupture is approximately 8 – 10 per 100,000 people. […] About 30,000 people in the United States suffer a brain aneurysm rupture each year. A brain aneurysm ruptures every 18 minutes. […] There are almost 500,000 deaths worldwide each year caused by brain aneurysms, and half the victims are younger than 50. […] Brain aneurysms are most prevalent in people ages 35 to 60, but can occur in children as well. Most aneurysms develop after the age of 40. […] Women are more likely than men to have a brain aneurysm (3:2 ratio). […] Women, particularly those over the age of 55, have a higher risk of brain aneurysm rupture than men (about 1.5 times the risk). […] African-Americans and Hispanics are about twice as likely to have a brain aneurysm rupture compared to caucasians.

• #12 The Medical Minute: The dangers of cerebral aneurysms – Penn State Health News

  https://pennstatehealthnews.org/2024/05/the-medical-minute-the-dangers-of-cerebral-aneurysms/

  For roughly 6.8 million Americans currently living with aneurysms, those blisters occur in the brain, according to the Brain Aneurysm Foundation. […] According to the Brain Aneurysm Foundation: Most people who have brain aneurysms are ages 35-60, but they can happen in all age groups including children. Most people develop aneurysms after they turn 40. […] For the general population, doctors dont recommend testing. However, if you have more than one relative with an aneurysm, doctors recommend screening every five years starting at age 30, Simon said. […] In many cases, you dont. Often aneurysms dont rupture, grow or cause problems, and doctors opt to keep them under surveillance to make sure they stay that way.

• #13 Cerebral Aneurysm – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507902/

  Cerebral aneurysms are defined as dilations that occur at weak points along the arterial circulation within the brain. The majority of cerebral aneurysms are silent and may be found incidentally on neuroimaging or upon autopsy. Approximately 85% of aneurysms are located in the anterior circulation, predominately at junctions or bifurcations along the circle of Willis. Subarachnoid hemorrhage (SAH) usually occurs with rupture and is associated with a high rate of morbidity and mortality. […] The worldwide prevalence of cerebral aneurysms is approximately 3.2%, with a mean age of 50 and an overall 1:1 gender ratio. This ratio changes significantly after age 50, with an increasing female predominance approaching 2:1, thought to be due to decreased circulating estrogen causing a reduction in the collagen content of the vascular tissue. The rate of rupture causing SAH is about 10 per 100,000. This is higher in certain populations such as the Finnish and Japanese. However, this is not due to a higher prevalence of aneurysms in these populations. The overall mortality due to aneurysmal SAH is considered to be 0.4 to 0.6% of all-cause deaths, with an approximate 20% mortality and an additional 30 to 40% morbidity in patients with known rupture.

• #14 Statistics and Facts – Brain Aneurysm Foundation

  https://www.bafound.org/statistics-and-facts/

  An estimated 6.8 million people in the United States have an unruptured brain aneurysm, or 1 in 50 people. […] The annual rate of rupture is approximately 8 – 10 per 100,000 people. […] About 30,000 people in the United States suffer a brain aneurysm rupture each year. A brain aneurysm ruptures every 18 minutes. […] There are almost 500,000 deaths worldwide each year caused by brain aneurysms, and half the victims are younger than 50. […] Brain aneurysms are most prevalent in people ages 35 to 60, but can occur in children as well. Most aneurysms develop after the age of 40. […] Women are more likely than men to have a brain aneurysm (3:2 ratio). […] Women, particularly those over the age of 55, have a higher risk of brain aneurysm rupture than men (about 1.5 times the risk). […] African-Americans and Hispanics are about twice as likely to have a brain aneurysm rupture compared to caucasians.

• #15 Cerebral Aneurysm: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1161518-overview

  The frequency of cerebral aneurysms is difficult to ascertain because of variation in the definitions of the size of aneurysm and modes of detection. Autopsy series cite a prevalence range of 1%5%. Prevalence ranges from 5-10%, with unruptured aneurysms accounting for 50% of all aneurysms. Pediatric aneurysms account for only 2% of all cerebral aneurysms. In the United States, the incidence of ruptured aneurysms is approximately 12 per 100,000 individuals or 30,000 annual cases of aneurysmal SAH. The frequency of cerebral aneurysms has not declined in recent years. […] Incidence of aneurysmal SAH varies widely depending on geographic location, with Finland and Japan having the highest reported rates. Overall, the incidence has been estimated at 10.5 per 100,000 individuals. […] The racial predilection of cerebral aneurysms is largely unknown, although a higher incidence has been noted in African Americans, with an odds ratio of 2:1.

• #16 Traumatic intracranial aneurysms | MedLink Neurology

  https://www.medlink.com/articles/traumatic-intracranial-aneurysms

  Traumatic intracranial aneurysms constitute less than 1% of adult aneurysms; however, they account for more than 20% of pediatric aneurysms. […] The incidence of traumatic intracranial aneurysms caused by penetrating trauma across studies is approximately 2% to 6% across studies. […] Among wartime patients with closed and penetrating head injuries deemed to warrant angiography, there was a 34% prevalence of vascular injuries, with traumatic intracranial aneurysms constituting the majority. […] The reported incidence of vascular injury in civilian penetrating brain injury ranges between 38% and 50%. […] Traumatic intracranial aneurysms have a higher rate of rupture and growth compared to true saccular aneurysms. It is estimated that 40% will hemorrhage and 21% will grow in size on follow-up imaging.

• #17 Exploring Aneurysm Risk Factors in Different Age Groups – CVRTI

  https://cvrti.utah.edu/exploring-aneurysm-risk-factors-in-different-age-groups/

  Aneurysms, characterized by a strange bulge in a blood vessels wall, can create major health risks for people of all kinds. Being aware of which demographics are more likely to experience aneurysms, as well as age-specific risk factors and guidelines to follow, is crucial for preventing and managing this potentially life-threatening disease. […] This article will detail the complexities of aneurysms, especially how the risk changes with age, the groups most likely to experience the condition, and the recommended follow-ups in a medical environment. […] First, an aneurysm can happen to anyone of any age. However, they are most common for adults between the ages of 30 and 60. Pediatric aneurysms are uncommon and tend to be different from those that adults experience. […] As people age, their risk factors also increases. This is largely due to the deterioration of blood vessel strength and elasticity. For instance, intracranial aneurysms are most commonly diagnosed in those between 40 and 60. This age group might have several risk factors, such as high cholesterol, high blood pressure, and smoking.

• #18 An Analysis of the Incidence and Cost of Intracranial Aneurysm and Subarachnoid Haemorrhage Treatment between 2013 and 2021

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10001767/

  The incidence of unruptured intracranial aneurysms (UIAs) amounts to 3.2% among adults. […] The annual risk of aneurysm rupture is 2-10% and it results in subarachnoid haemorrhage (SAH). […] The overall incidence of SAH is 9.1 per 100,000 person-years in most regions of the world, yielding approximately 36,000 SAH cases per year in Europe. […] The incidence of SAH increases with the age of the patient, the mean age of the first SAH incidence in a lifetime is 52 years. […] The changes that were observed in the rate of change of the value of services prescribed per patient or per hospitalisation were highly consistent. […] The overall number of patients hospitalised with diagnosis of UIA or SAH is not decreasing in subsequent years of observation. […] The recorded changes in the dynamics of the value of medical services per patient or per hospitalisation largely coincided.

• #19 Statistics and Facts – Brain Aneurysm Foundation

  https://www.bafound.org/statistics-and-facts/

  An estimated 6.8 million people in the United States have an unruptured brain aneurysm, or 1 in 50 people. […] The annual rate of rupture is approximately 8 – 10 per 100,000 people. […] About 30,000 people in the United States suffer a brain aneurysm rupture each year. A brain aneurysm ruptures every 18 minutes. […] There are almost 500,000 deaths worldwide each year caused by brain aneurysms, and half the victims are younger than 50. […] Brain aneurysms are most prevalent in people ages 35 to 60, but can occur in children as well. Most aneurysms develop after the age of 40. […] Women are more likely than men to have a brain aneurysm (3:2 ratio). […] Women, particularly those over the age of 55, have a higher risk of brain aneurysm rupture than men (about 1.5 times the risk). […] African-Americans and Hispanics are about twice as likely to have a brain aneurysm rupture compared to caucasians.

• #20 Brain aneurysms: Prevalence and more

  https://www.medicalnewstoday.com/articles/how-common-are-brain-aneurysms

  Unruptured aneurysms affect about 3.2% of people worldwide. Ruptured aneurysms are less common, occurring in approximately 10 per 100,000 cases. […] In the United States, about 6.7 million individuals have the unruptured type, and rupture happens in an estimated 30,000 annually. Hispanic and African American people have twice the risk. […] Worldwide, the condition causes 500,000 deaths annually half of which are people younger than 50 years. […] After a rupture of a cerebral aneurysm, the illness and death rate is very high. Evidence indicates that within the first 24 hours, nearly 25% of people die, and 50% die within 3 months. Factors that can influence outlook include age, presence of high blood pressure and other co-occurring conditions, the extent of the bleeding from the rupture, degree of vasospasms, which are contractions of arteries in the brain that limit blood flow, and neurological status. […] In the U.S., about 6.7 million people have an unruptured brain aneurysm, and about 30,000 per year have the ruptured type. […] Various factors such as genetics, smoking, and untreated high blood pressure can increase a person’s risk of the condition.

• #21 Cerebral Aneurysm: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1161518-overview

  The frequency of cerebral aneurysms is difficult to ascertain because of variation in the definitions of the size of aneurysm and modes of detection. Autopsy series cite a prevalence range of 1%5%. Prevalence ranges from 5-10%, with unruptured aneurysms accounting for 50% of all aneurysms. Pediatric aneurysms account for only 2% of all cerebral aneurysms. In the United States, the incidence of ruptured aneurysms is approximately 12 per 100,000 individuals or 30,000 annual cases of aneurysmal SAH. The frequency of cerebral aneurysms has not declined in recent years. […] Incidence of aneurysmal SAH varies widely depending on geographic location, with Finland and Japan having the highest reported rates. Overall, the incidence has been estimated at 10.5 per 100,000 individuals. […] The racial predilection of cerebral aneurysms is largely unknown, although a higher incidence has been noted in African Americans, with an odds ratio of 2:1.

• #22 Cerebral Aneurysm – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507902/

  Cerebral aneurysms are defined as dilations that occur at weak points along the arterial circulation within the brain. The majority of cerebral aneurysms are silent and may be found incidentally on neuroimaging or upon autopsy. Approximately 85% of aneurysms are located in the anterior circulation, predominately at junctions or bifurcations along the circle of Willis. Subarachnoid hemorrhage (SAH) usually occurs with rupture and is associated with a high rate of morbidity and mortality. […] The worldwide prevalence of cerebral aneurysms is approximately 3.2%, with a mean age of 50 and an overall 1:1 gender ratio. This ratio changes significantly after age 50, with an increasing female predominance approaching 2:1, thought to be due to decreased circulating estrogen causing a reduction in the collagen content of the vascular tissue. The rate of rupture causing SAH is about 10 per 100,000. This is higher in certain populations such as the Finnish and Japanese. However, this is not due to a higher prevalence of aneurysms in these populations. The overall mortality due to aneurysmal SAH is considered to be 0.4 to 0.6% of all-cause deaths, with an approximate 20% mortality and an additional 30 to 40% morbidity in patients with known rupture.

• #23 Cerebral Aneurysm: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1161518-overview

  The frequency of cerebral aneurysms is difficult to ascertain because of variation in the definitions of the size of aneurysm and modes of detection. Autopsy series cite a prevalence range of 1%5%. Prevalence ranges from 5-10%, with unruptured aneurysms accounting for 50% of all aneurysms. Pediatric aneurysms account for only 2% of all cerebral aneurysms. In the United States, the incidence of ruptured aneurysms is approximately 12 per 100,000 individuals or 30,000 annual cases of aneurysmal SAH. The frequency of cerebral aneurysms has not declined in recent years. […] Incidence of aneurysmal SAH varies widely depending on geographic location, with Finland and Japan having the highest reported rates. Overall, the incidence has been estimated at 10.5 per 100,000 individuals. […] The racial predilection of cerebral aneurysms is largely unknown, although a higher incidence has been noted in African Americans, with an odds ratio of 2:1.

• #24 An Analysis of the Incidence and Cost of Intracranial Aneurysm and Subarachnoid Haemorrhage Treatment between 2013 and 2021

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10001767/

  The incidence of unruptured intracranial aneurysms (UIAs) amounts to 3.2% among adults. […] The annual risk of aneurysm rupture is 2-10% and it results in subarachnoid haemorrhage (SAH). […] The overall incidence of SAH is 9.1 per 100,000 person-years in most regions of the world, yielding approximately 36,000 SAH cases per year in Europe. […] The incidence of SAH increases with the age of the patient, the mean age of the first SAH incidence in a lifetime is 52 years. […] The changes that were observed in the rate of change of the value of services prescribed per patient or per hospitalisation were highly consistent. […] The overall number of patients hospitalised with diagnosis of UIA or SAH is not decreasing in subsequent years of observation. […] The recorded changes in the dynamics of the value of medical services per patient or per hospitalisation largely coincided.

• #25 Screening for intracranial aneurysm – UpToDate

  https://www.uptodate.com/contents/screening-for-intracranial-aneurysm

  Screening for intracranial aneurysm […] Most SAHs are caused by ruptured saccular aneurysms. Recommendations for screening for aneurysms and methods of screening are discussed here. The epidemiology and pathogenesis of intracranial aneurysms, management of unruptured aneurysms, and screening for new aneurysms after treatment for SAH are discussed separately. […] Widespread screening for cerebral aneurysm is not warranted. This was also the conclusion in guidelines published by the American Stroke Association. […] The prevalence of intracranial saccular aneurysms by radiographic and autopsy series is approximately 0.4 to 6.0 percent, or between 1 and 18 million people in the United States. In adult patients without risk factors, the best estimate is that approximately 2 percent harbor asymptomatic cerebral aneurysms. Aneurysmal subarachnoid hemorrhage (SAH) occurs at an estimated rate of 6 to 16 per 100,000 population. In North America, this translates into approximately 30,000 affected persons per year. Thus, most aneurysms do not rupture.

• #26 Brain aneurysms: Prevalence and more

  https://www.medicalnewstoday.com/articles/how-common-are-brain-aneurysms

  Unruptured aneurysms affect about 3.2% of people worldwide. Ruptured aneurysms are less common, occurring in approximately 10 per 100,000 cases. […] In the United States, about 6.7 million individuals have the unruptured type, and rupture happens in an estimated 30,000 annually. Hispanic and African American people have twice the risk. […] Worldwide, the condition causes 500,000 deaths annually half of which are people younger than 50 years. […] After a rupture of a cerebral aneurysm, the illness and death rate is very high. Evidence indicates that within the first 24 hours, nearly 25% of people die, and 50% die within 3 months. Factors that can influence outlook include age, presence of high blood pressure and other co-occurring conditions, the extent of the bleeding from the rupture, degree of vasospasms, which are contractions of arteries in the brain that limit blood flow, and neurological status. […] In the U.S., about 6.7 million people have an unruptured brain aneurysm, and about 30,000 per year have the ruptured type. […] Various factors such as genetics, smoking, and untreated high blood pressure can increase a person’s risk of the condition.

• #27 Statistics and Facts – Brain Aneurysm Foundation

  https://www.bafound.org/statistics-and-facts/

  An estimated 6.8 million people in the United States have an unruptured brain aneurysm, or 1 in 50 people. […] The annual rate of rupture is approximately 8 – 10 per 100,000 people. […] About 30,000 people in the United States suffer a brain aneurysm rupture each year. A brain aneurysm ruptures every 18 minutes. […] There are almost 500,000 deaths worldwide each year caused by brain aneurysms, and half the victims are younger than 50. […] Brain aneurysms are most prevalent in people ages 35 to 60, but can occur in children as well. Most aneurysms develop after the age of 40. […] Women are more likely than men to have a brain aneurysm (3:2 ratio). […] Women, particularly those over the age of 55, have a higher risk of brain aneurysm rupture than men (about 1.5 times the risk). […] African-Americans and Hispanics are about twice as likely to have a brain aneurysm rupture compared to caucasians.

• #28 Brain aneurysms: Prevalence and more

  https://www.medicalnewstoday.com/articles/how-common-are-brain-aneurysms

  Unruptured aneurysms affect about 3.2% of people worldwide. Ruptured aneurysms are less common, occurring in approximately 10 per 100,000 cases. […] In the United States, about 6.7 million individuals have the unruptured type, and rupture happens in an estimated 30,000 annually. Hispanic and African American people have twice the risk. […] Worldwide, the condition causes 500,000 deaths annually half of which are people younger than 50 years. […] After a rupture of a cerebral aneurysm, the illness and death rate is very high. Evidence indicates that within the first 24 hours, nearly 25% of people die, and 50% die within 3 months. Factors that can influence outlook include age, presence of high blood pressure and other co-occurring conditions, the extent of the bleeding from the rupture, degree of vasospasms, which are contractions of arteries in the brain that limit blood flow, and neurological status. […] In the U.S., about 6.7 million people have an unruptured brain aneurysm, and about 30,000 per year have the ruptured type. […] Various factors such as genetics, smoking, and untreated high blood pressure can increase a person’s risk of the condition.

• #29 Statistics and Facts – Brain Aneurysm Foundation

  https://www.bafound.org/statistics-and-facts/

  An estimated 6.8 million people in the United States have an unruptured brain aneurysm, or 1 in 50 people. […] The annual rate of rupture is approximately 8 – 10 per 100,000 people. […] About 30,000 people in the United States suffer a brain aneurysm rupture each year. A brain aneurysm ruptures every 18 minutes. […] There are almost 500,000 deaths worldwide each year caused by brain aneurysms, and half the victims are younger than 50. […] Brain aneurysms are most prevalent in people ages 35 to 60, but can occur in children as well. Most aneurysms develop after the age of 40. […] Women are more likely than men to have a brain aneurysm (3:2 ratio). […] Women, particularly those over the age of 55, have a higher risk of brain aneurysm rupture than men (about 1.5 times the risk). […] African-Americans and Hispanics are about twice as likely to have a brain aneurysm rupture compared to caucasians.

• #30 An Analysis of the Incidence and Cost of Intracranial Aneurysm and Subarachnoid Haemorrhage Treatment between 2013 and 2021

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10001767/

  The incidence of unruptured intracranial aneurysms (UIAs) amounts to 3.2% among adults. […] The annual risk of aneurysm rupture is 2-10% and it results in subarachnoid haemorrhage (SAH). […] The overall incidence of SAH is 9.1 per 100,000 person-years in most regions of the world, yielding approximately 36,000 SAH cases per year in Europe. […] The incidence of SAH increases with the age of the patient, the mean age of the first SAH incidence in a lifetime is 52 years. […] The changes that were observed in the rate of change of the value of services prescribed per patient or per hospitalisation were highly consistent. […] The overall number of patients hospitalised with diagnosis of UIA or SAH is not decreasing in subsequent years of observation. […] The recorded changes in the dynamics of the value of medical services per patient or per hospitalisation largely coincided.

• #31

  https://journals.lww.com/neurosurgpraconline/fulltext/2020/12000/intracranial_aneurysms__does_size_really_matter_.5.aspx

  To stratify the risk of aneurysmal rupture, size remains the primary criterion as proposed by 2 ISUIA (International Study of Unruptured Intracranial Aneurysms) trials that recommend the observation of 7mm aneurysms because of their low propensity to rupture. […] The morbidity and mortality associated with subarachnoid hemorrhage (SAH) resulting from ruptured intracranial aneurysms (IAs) are significant. The reported annual risk of hemorrhage is 1.4% and the mortality around 50%. Half the survivors end up with permanent brain damage. A size of 7mm has become a significant determinant for the risk of SAH. However, controversy persists regarding its practical applicability. […] Factors beyond size appear to play a role in aneurysmal rupture. Age, hypertension, prior SAH, and geographical location (ie, Japanese and Finnish populations) are some of the known risk factors associated with aneurysmal rupture.

• #32 Insomnia May Be Risk Factor for Highly Fatal Brain Aneurysm Rupture | Sleep Review

  https://sleepreviewmag.com/sleep-disorders/insomnia/insomnia-may-be-risk-factor-for-highly-fatal-brain-aneurysm-rupture/

  Insomnia may be a potential risk factor for a brain bleed from a ruptured aneurysm along with more well known risk factors of smoking and high blood pressure, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association. […] More than 3% of adults worldwide have unruptured blood vessel malformations in the brain called intracranial aneurysms, the majority of which will never rupture. About 2.5% of intracranial aneurysms will rupture, resulting in a subarachnoid hemorrhage (SAH), also called a brain bleed. […] Ruptured aneurysms are highly fatal. It is, therefore, extremely important to identify modifiable risk factors that can help prevent aneurysms from rupturing, says study author Susanna C. Larsson, PhD, associate professor in the unit of cardiovascular and nutritional epidemiology at the Karolinska Institutet in Stockholm, Sweden, and the unit of medical epidemiology at Uppsala University in Uppsala, Sweden, in a release.

• #33 Screening for intracranial aneurysm – UpToDate

  https://www.uptodate.com/contents/screening-for-intracranial-aneurysm

  The probability of rupture is related to the size of the aneurysm. Small aneurysms (<6 mm in diameter) are most commonly identified with screening, and these are at low risk for rupture. In addition, patients with smaller aneurysms (<10 mm) that have ruptured have a better prognosis than larger aneurysm rupture.

• #34 Intracranial Aneurysms: Current Evidence and Clinical Practice | AAFP

  https://www.aafp.org/pubs/afp/issues/2002/0815/p601.html

  Unruptured intracranial aneurysms occur in up to 6 percent of the general population. […] A recent systematic review of studies involving more than 56,000 patients found that unruptured intracranial aneurysms occur in 3.6 to 6 percent of the general population. […] The incidence of intracranial aneurysms is between 8 and 9 percent in persons with two or more relatives who have had a subarachnoid hemorrhage or an aneurysm. […] Recent data have shown that age over 50 years, female gender, and current cigarette smoking are risk factors for intracranial aneurysm. […] Since 1984, cocaine use has been linked to the formation and rupture of aneurysms. […] The findings of the International Study of Unruptured Intracranial Aneurysms (ISUIA) were published in 1998. […] The ISUIA data suggest that aneurysms with a diameter of 10 mm or more are at critical risk for rupture.

• #35

  https://journals.lww.com/neurosurgpraconline/fulltext/2020/12000/intracranial_aneurysms__does_size_really_matter_.5.aspx

  To stratify the risk of aneurysmal rupture, size remains the primary criterion as proposed by 2 ISUIA (International Study of Unruptured Intracranial Aneurysms) trials that recommend the observation of 7mm aneurysms because of their low propensity to rupture. […] The morbidity and mortality associated with subarachnoid hemorrhage (SAH) resulting from ruptured intracranial aneurysms (IAs) are significant. The reported annual risk of hemorrhage is 1.4% and the mortality around 50%. Half the survivors end up with permanent brain damage. A size of 7mm has become a significant determinant for the risk of SAH. However, controversy persists regarding its practical applicability. […] Factors beyond size appear to play a role in aneurysmal rupture. Age, hypertension, prior SAH, and geographical location (ie, Japanese and Finnish populations) are some of the known risk factors associated with aneurysmal rupture.

• #36

  https://journals.lww.com/neurosurgpraconline/fulltext/2020/12000/intracranial_aneurysms__does_size_really_matter_.5.aspx

  To stratify the risk of aneurysmal rupture, size remains the primary criterion as proposed by 2 ISUIA (International Study of Unruptured Intracranial Aneurysms) trials that recommend the observation of 7mm aneurysms because of their low propensity to rupture. […] The morbidity and mortality associated with subarachnoid hemorrhage (SAH) resulting from ruptured intracranial aneurysms (IAs) are significant. The reported annual risk of hemorrhage is 1.4% and the mortality around 50%. Half the survivors end up with permanent brain damage. A size of 7mm has become a significant determinant for the risk of SAH. However, controversy persists regarding its practical applicability. […] Factors beyond size appear to play a role in aneurysmal rupture. Age, hypertension, prior SAH, and geographical location (ie, Japanese and Finnish populations) are some of the known risk factors associated with aneurysmal rupture.

• #37 Aneurysmal Subarachnoid Hemorrhage Part 1: Epidemiology, Pathophysiology, Diagnosis, Cardiac Complications – OpenAnesthesia

  https://www.openanesthesia.org/keywords/aneurysmal-subarachnoid-hemorrhage-part-1-epidemiology-pathophysiology-diagnosis-cardiac-complications/

  Stroke is the second leading cause of death. In the United States, the annual incidence of a new or recurring stroke is 795,000, of which 87% are ischemic, 10% are intracranial hemorrhages (ICH), and 3% are SAH. Globally, 62% are ischemic, 28% are ICH, and 10% are SAH. […] The global incidence of aSAH is 2 to 16 per 100,000. The incidence varies by ethnicity and geography. […] The lowest incidence of SAH is in China, followed by Central and South America, United States, while the highest incidence is in Finland and Japan. […] Women are more likely to be affected than men by a factor of 1.24. […] A higher incidence of SAH is seen among Black and Hispanic patients. […] Most aneurysms occur between 40-60 years of age, with a mean age of rupture between 50 and 55 years. […] Risk factors for SAH include: Aneurysm size and location: larger aneurysms and posterior circulation aneurysms at an increased risk for rupture; Smoking: most important preventable risk factor for SAH; Hypertension: major risk factor; Genetic risk and family history of SAH; Prior history of aSAH; Moderate to heavy alcohol abuse; Use of sympathomimetic drugs: methamphetamine and cocaine abuse; Estrogen deficiency; Antithrombotic therapy, etc. […] SAH is associated with an increased risk of mortality: About 10-15% of patients die before hospitalization, and 25% die within the first 48 hours. Initial hemorrhage is usually the primary cause of death, followed by rebleeding.

• #38 Cerebral Aneurysms | East Bay Brain & Spine

  https://www.eastbaybrainandspine.com/conditions/vascular/cerebral-aneurysms-overview/

  Cerebral aneurysms are relatively common, affecting approximately 3-5% of the population. […] The incidence of cerebral aneurysms varies by ethnicity, with certain racial and ethnic groups having a higher risk. For instance, African Americans and Hispanics are 1.5 to 2 times more likely to develop cerebral aneurysms compared to Caucasians. […] Several factors can increase the likelihood of a cerebral aneurysm rupturing. These include smoking, hypertension, a family history of cerebral aneurysms, female gender, and certain genetic disorders such as polycystic kidney disease and Ehlers-Danlos syndrome. […] Studies have suggested that about 7-20% of patients with a brain aneurysm have a family history of the condition. Individuals with a first-degree relative (parent, sibling, or child) who has experienced a brain aneurysm are considered to be at a higher risk.

• #39 Aneurysmal Subarachnoid Hemorrhage Part 1: Epidemiology, Pathophysiology, Diagnosis, Cardiac Complications – OpenAnesthesia

  https://www.openanesthesia.org/keywords/aneurysmal-subarachnoid-hemorrhage-part-1-epidemiology-pathophysiology-diagnosis-cardiac-complications/

  Stroke is the second leading cause of death. In the United States, the annual incidence of a new or recurring stroke is 795,000, of which 87% are ischemic, 10% are intracranial hemorrhages (ICH), and 3% are SAH. Globally, 62% are ischemic, 28% are ICH, and 10% are SAH. […] The global incidence of aSAH is 2 to 16 per 100,000. The incidence varies by ethnicity and geography. […] The lowest incidence of SAH is in China, followed by Central and South America, United States, while the highest incidence is in Finland and Japan. […] Women are more likely to be affected than men by a factor of 1.24. […] A higher incidence of SAH is seen among Black and Hispanic patients. […] Most aneurysms occur between 40-60 years of age, with a mean age of rupture between 50 and 55 years. […] Risk factors for SAH include: Aneurysm size and location: larger aneurysms and posterior circulation aneurysms at an increased risk for rupture; Smoking: most important preventable risk factor for SAH; Hypertension: major risk factor; Genetic risk and family history of SAH; Prior history of aSAH; Moderate to heavy alcohol abuse; Use of sympathomimetic drugs: methamphetamine and cocaine abuse; Estrogen deficiency; Antithrombotic therapy, etc. […] SAH is associated with an increased risk of mortality: About 10-15% of patients die before hospitalization, and 25% die within the first 48 hours. Initial hemorrhage is usually the primary cause of death, followed by rebleeding.

• #40 Statistics and Facts – Brain Aneurysm Foundation

  https://www.bafound.org/statistics-and-facts/

  An estimated 6.8 million people in the United States have an unruptured brain aneurysm, or 1 in 50 people. […] The annual rate of rupture is approximately 8 – 10 per 100,000 people. […] About 30,000 people in the United States suffer a brain aneurysm rupture each year. A brain aneurysm ruptures every 18 minutes. […] There are almost 500,000 deaths worldwide each year caused by brain aneurysms, and half the victims are younger than 50. […] Brain aneurysms are most prevalent in people ages 35 to 60, but can occur in children as well. Most aneurysms develop after the age of 40. […] Women are more likely than men to have a brain aneurysm (3:2 ratio). […] Women, particularly those over the age of 55, have a higher risk of brain aneurysm rupture than men (about 1.5 times the risk). […] African-Americans and Hispanics are about twice as likely to have a brain aneurysm rupture compared to caucasians.

• #41 Brain aneurysms: Prevalence and more

  https://www.medicalnewstoday.com/articles/how-common-are-brain-aneurysms

  Unruptured aneurysms affect about 3.2% of people worldwide. Ruptured aneurysms are less common, occurring in approximately 10 per 100,000 cases. […] In the United States, about 6.7 million individuals have the unruptured type, and rupture happens in an estimated 30,000 annually. Hispanic and African American people have twice the risk. […] Worldwide, the condition causes 500,000 deaths annually half of which are people younger than 50 years. […] After a rupture of a cerebral aneurysm, the illness and death rate is very high. Evidence indicates that within the first 24 hours, nearly 25% of people die, and 50% die within 3 months. Factors that can influence outlook include age, presence of high blood pressure and other co-occurring conditions, the extent of the bleeding from the rupture, degree of vasospasms, which are contractions of arteries in the brain that limit blood flow, and neurological status. […] In the U.S., about 6.7 million people have an unruptured brain aneurysm, and about 30,000 per year have the ruptured type. […] Various factors such as genetics, smoking, and untreated high blood pressure can increase a person’s risk of the condition.

• #42 Statistics and Facts – Brain Aneurysm Foundation

  https://www.bafound.org/statistics-and-facts/

  Ruptured brain aneurysms are fatal in about 50% of cases. Of those who survive, about 66% suffer some permanent neurological deficit. […] Approximately 15% of people with a ruptured aneurysm die before reaching the hospital. Most of the deaths are due to rapid and massive brain injury from the initial bleeding. […] Accurate early diagnosis of a ruptured brain aneurysm is critical, as the initial hemorrhage may be fatal or result in devastating neurologic outcomes. […] Despite the widespread availability of brain imaging that can detect a ruptured brain aneurysm, misdiagnosis or delays in diagnosis occur in up to one quarter of patients when initially seeking medical attention. In three out of four cases, misdiagnosis results from a failure to do a scan. […] The treatment of ruptured brain aneurysms is far more costly than the treatment of unruptured aneurysms: The cost of a brain aneurysm treated by surgical clipping more than doubles after the aneurysm has ruptured. The cost of a brain aneurysm treated by endovascular coiling increases by about 70% after the aneurysm has ruptured.

• #43 Brain aneurysms: Prevalence and more

  https://www.medicalnewstoday.com/articles/how-common-are-brain-aneurysms

  Unruptured aneurysms affect about 3.2% of people worldwide. Ruptured aneurysms are less common, occurring in approximately 10 per 100,000 cases. […] In the United States, about 6.7 million individuals have the unruptured type, and rupture happens in an estimated 30,000 annually. Hispanic and African American people have twice the risk. […] Worldwide, the condition causes 500,000 deaths annually half of which are people younger than 50 years. […] After a rupture of a cerebral aneurysm, the illness and death rate is very high. Evidence indicates that within the first 24 hours, nearly 25% of people die, and 50% die within 3 months. Factors that can influence outlook include age, presence of high blood pressure and other co-occurring conditions, the extent of the bleeding from the rupture, degree of vasospasms, which are contractions of arteries in the brain that limit blood flow, and neurological status. […] In the U.S., about 6.7 million people have an unruptured brain aneurysm, and about 30,000 per year have the ruptured type. […] Various factors such as genetics, smoking, and untreated high blood pressure can increase a person’s risk of the condition.

• #44 Aneurysmal Subarachnoid Hemorrhage Part 1: Epidemiology, Pathophysiology, Diagnosis, Cardiac Complications – OpenAnesthesia

  https://www.openanesthesia.org/keywords/aneurysmal-subarachnoid-hemorrhage-part-1-epidemiology-pathophysiology-diagnosis-cardiac-complications/

  Stroke is the second leading cause of death. In the United States, the annual incidence of a new or recurring stroke is 795,000, of which 87% are ischemic, 10% are intracranial hemorrhages (ICH), and 3% are SAH. Globally, 62% are ischemic, 28% are ICH, and 10% are SAH. […] The global incidence of aSAH is 2 to 16 per 100,000. The incidence varies by ethnicity and geography. […] The lowest incidence of SAH is in China, followed by Central and South America, United States, while the highest incidence is in Finland and Japan. […] Women are more likely to be affected than men by a factor of 1.24. […] A higher incidence of SAH is seen among Black and Hispanic patients. […] Most aneurysms occur between 40-60 years of age, with a mean age of rupture between 50 and 55 years. […] Risk factors for SAH include: Aneurysm size and location: larger aneurysms and posterior circulation aneurysms at an increased risk for rupture; Smoking: most important preventable risk factor for SAH; Hypertension: major risk factor; Genetic risk and family history of SAH; Prior history of aSAH; Moderate to heavy alcohol abuse; Use of sympathomimetic drugs: methamphetamine and cocaine abuse; Estrogen deficiency; Antithrombotic therapy, etc. […] SAH is associated with an increased risk of mortality: About 10-15% of patients die before hospitalization, and 25% die within the first 48 hours. Initial hemorrhage is usually the primary cause of death, followed by rebleeding.

• #45 Cerebral Aneurysm – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507902/

  Cerebral aneurysms are defined as dilations that occur at weak points along the arterial circulation within the brain. The majority of cerebral aneurysms are silent and may be found incidentally on neuroimaging or upon autopsy. Approximately 85% of aneurysms are located in the anterior circulation, predominately at junctions or bifurcations along the circle of Willis. Subarachnoid hemorrhage (SAH) usually occurs with rupture and is associated with a high rate of morbidity and mortality. […] The worldwide prevalence of cerebral aneurysms is approximately 3.2%, with a mean age of 50 and an overall 1:1 gender ratio. This ratio changes significantly after age 50, with an increasing female predominance approaching 2:1, thought to be due to decreased circulating estrogen causing a reduction in the collagen content of the vascular tissue. The rate of rupture causing SAH is about 10 per 100,000. This is higher in certain populations such as the Finnish and Japanese. However, this is not due to a higher prevalence of aneurysms in these populations. The overall mortality due to aneurysmal SAH is considered to be 0.4 to 0.6% of all-cause deaths, with an approximate 20% mortality and an additional 30 to 40% morbidity in patients with known rupture.

• #46 Screening for intracranial aneurysm – UpToDate

  https://www.uptodate.com/contents/screening-for-intracranial-aneurysm

  Screening for intracranial aneurysm […] Most SAHs are caused by ruptured saccular aneurysms. Recommendations for screening for aneurysms and methods of screening are discussed here. The epidemiology and pathogenesis of intracranial aneurysms, management of unruptured aneurysms, and screening for new aneurysms after treatment for SAH are discussed separately. […] Widespread screening for cerebral aneurysm is not warranted. This was also the conclusion in guidelines published by the American Stroke Association. […] The prevalence of intracranial saccular aneurysms by radiographic and autopsy series is approximately 0.4 to 6.0 percent, or between 1 and 18 million people in the United States. In adult patients without risk factors, the best estimate is that approximately 2 percent harbor asymptomatic cerebral aneurysms. Aneurysmal subarachnoid hemorrhage (SAH) occurs at an estimated rate of 6 to 16 per 100,000 population. In North America, this translates into approximately 30,000 affected persons per year. Thus, most aneurysms do not rupture.

• #47 Intracranial Aneurysms: Current Evidence and Clinical Practice | AAFP

  https://www.aafp.org/pubs/afp/issues/2002/0815/p601.html

  Surveillance of patients from the ISUIA is ongoing and will help to define the risk of aneurysmal rupture over time. […] Screening of asymptomatic patients without risk factors does not appear to provide any benefits. […] Screening of patients with acquired risk factors, such as smoking or alcohol abuse, is not recommended. […] Screening of patients with a positive family history of ruptured intracranial aneurysm is controversial. […] The issue of screening in patients who have two or more family members with intracranial aneurysms is more complicated. […] Therefore, the decision on whether or not to screen for intracranial aneurysms in patients who have two or more first-degree relatives with documented subarachnoid hemorrhage is best decided on a case-by-case basis. […] In patients with a history of aneurysmal subarachnoid hemorrhage, the annual rate of new aneurysm formation is between 1 and 2 percent, and the risk of aneurysmal rupture appears to be increased.

• #48 Screening for intracranial aneurysm – UpToDate

  https://www.uptodate.com/contents/screening-for-intracranial-aneurysm

  Screening for intracranial aneurysm […] Most SAHs are caused by ruptured saccular aneurysms. Recommendations for screening for aneurysms and methods of screening are discussed here. The epidemiology and pathogenesis of intracranial aneurysms, management of unruptured aneurysms, and screening for new aneurysms after treatment for SAH are discussed separately. […] Widespread screening for cerebral aneurysm is not warranted. This was also the conclusion in guidelines published by the American Stroke Association. […] The prevalence of intracranial saccular aneurysms by radiographic and autopsy series is approximately 0.4 to 6.0 percent, or between 1 and 18 million people in the United States. In adult patients without risk factors, the best estimate is that approximately 2 percent harbor asymptomatic cerebral aneurysms. Aneurysmal subarachnoid hemorrhage (SAH) occurs at an estimated rate of 6 to 16 per 100,000 population. In North America, this translates into approximately 30,000 affected persons per year. Thus, most aneurysms do not rupture.

• #49 Unruptured intracranial aneurysms – UpToDate

  https://www.uptodate.com/contents/unruptured-intracranial-aneurysms

  Unruptured intracranial aneurysms […] The epidemiology and pathogenesis of intracranial aneurysms and the management of unruptured aneurysms are discussed here. […] The recommendations provided are generally in agreement with those of the American Stroke Association as well as with those of the European Stroke Organization.

• #50

  https://www.nhs.uk/conditions/brain-aneurysm/diagnosis/

  A brain aneurysm is usually diagnosed using angiography. Angiography is a type of X-ray used to check blood vessels. […] There’s no routine screening programme for brain aneurysms and it’s unlikely that one will be introduced in future. Screening is only recommended for people thought to have a significant risk of having a brain aneurysm that could rupture at some point in the future. […] Screening may also be recommended if you have a condition that increases your chances of developing a brain aneurysm, such as autosomal dominant polycystic kidney disease.

• #51 Unruptured Intracranial Aneurysm: Screening, Prevalence and Risk Factors

  https://neurointervention.org/journal/view.php?number=348

  Consequently, Korean Clinical Practice Guidelines for UIA currently recommended that UIA should be screened according to the following three categories: 1) patients who have 2 or more first-degree relatives with an intracranial aneurysm; 2) patients with ADPKD; and 3) regular screening tests for new aneurysms for patients previously treated with aneurysmal SAH. […] Although the current guidelines do not support widespread screening for intracranial aneurysms in the general population, additional screening may be considered in patients with other genetic or medical conditions associated with intracranial aneurysms. […] Recently, according to the data from Korean National Health Insurance Service (NHIS), the number of treatments for UIA has increased because of the increased detection rate as well as increase in number of hospitals capable of performing embolization of UIA.

• #52 Unruptured Intracranial Aneurysm: Screening, Prevalence and Risk Factors

  https://neurointervention.org/journal/view.php?number=348

  Consequently, Korean Clinical Practice Guidelines for UIA currently recommended that UIA should be screened according to the following three categories: 1) patients who have 2 or more first-degree relatives with an intracranial aneurysm; 2) patients with ADPKD; and 3) regular screening tests for new aneurysms for patients previously treated with aneurysmal SAH. […] Although the current guidelines do not support widespread screening for intracranial aneurysms in the general population, additional screening may be considered in patients with other genetic or medical conditions associated with intracranial aneurysms. […] Recently, according to the data from Korean National Health Insurance Service (NHIS), the number of treatments for UIA has increased because of the increased detection rate as well as increase in number of hospitals capable of performing embolization of UIA.

• #53 Intracranial Aneurysms: Current Evidence and Clinical Practice | AAFP

  https://www.aafp.org/pubs/afp/issues/2002/0815/p601.html

  Unruptured intracranial aneurysms occur in up to 6 percent of the general population. […] A recent systematic review of studies involving more than 56,000 patients found that unruptured intracranial aneurysms occur in 3.6 to 6 percent of the general population. […] The incidence of intracranial aneurysms is between 8 and 9 percent in persons with two or more relatives who have had a subarachnoid hemorrhage or an aneurysm. […] Recent data have shown that age over 50 years, female gender, and current cigarette smoking are risk factors for intracranial aneurysm. […] Since 1984, cocaine use has been linked to the formation and rupture of aneurysms. […] The findings of the International Study of Unruptured Intracranial Aneurysms (ISUIA) were published in 1998. […] The ISUIA data suggest that aneurysms with a diameter of 10 mm or more are at critical risk for rupture.

• #54 Routine screening for individuals with a family history of aneurysm – Mayo Clinic

  https://www.mayoclinic.org/medical-professionals/neurology-neurosurgery/news/routine-screening-for-individuals-with-a-family-history-of-aneurysm/mac-20531273

  Although the precise etiology of brain aneurysm is unknown, the cause might include a genetic component. Mayo Clinic recommends regular MRI of individuals with a family history of aneurysm, to help prevent a ruptured aneurysm and hemorrhagic stroke. […] „Screening can be a wise approach to members of families that are prone to aneurysms,” says Bernard R. Bendok, M.D., chair of Neurologic Surgery at Mayo Clinic in Phoenix/Scottsdale, Arizona. „About 1% of the general population has an aneurysm. But in some families, the risk is as high as 30%. Treating an aneurysm before it ruptures is much more beneficial than treating it afterward.” […] Familial brain aneurysm tends to pose additional risks compared with brain aneurysm in individuals with no family history of the condition. „Familial brain aneurysms are more likely to have thinner walls than sporadic aneurysms have,” Dr. Bendok says. „People with familial brain aneurysms also tend to be about a decade younger when ruptures occur.”

• #55 Saccular cerebral aneurysm | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/saccular-cerebral-aneurysm?lang=us

  Prevalence of saccular cerebral aneurysms in the asymptomatic general population has been reported over a wide range (0.2-8.9%) when examined angiographically, and in 15-30% of these patients, multiple aneurysms are found. […] A familial tendency to aneurysms is also well recognized, with patients who have more than one first-degree relative affected, having a ~30% (range 17-44%) chance of themselves having an aneurysm.

• #56 Intracranial Aneurysms: Current Evidence and Clinical Practice | AAFP

  https://www.aafp.org/pubs/afp/issues/2002/0815/p601.html

  Surveillance of patients from the ISUIA is ongoing and will help to define the risk of aneurysmal rupture over time. […] Screening of asymptomatic patients without risk factors does not appear to provide any benefits. […] Screening of patients with acquired risk factors, such as smoking or alcohol abuse, is not recommended. […] Screening of patients with a positive family history of ruptured intracranial aneurysm is controversial. […] The issue of screening in patients who have two or more family members with intracranial aneurysms is more complicated. […] Therefore, the decision on whether or not to screen for intracranial aneurysms in patients who have two or more first-degree relatives with documented subarachnoid hemorrhage is best decided on a case-by-case basis. […] In patients with a history of aneurysmal subarachnoid hemorrhage, the annual rate of new aneurysm formation is between 1 and 2 percent, and the risk of aneurysmal rupture appears to be increased.

• #57 The Medical Minute: The dangers of cerebral aneurysms – Penn State Health News

  https://pennstatehealthnews.org/2024/05/the-medical-minute-the-dangers-of-cerebral-aneurysms/

  For roughly 6.8 million Americans currently living with aneurysms, those blisters occur in the brain, according to the Brain Aneurysm Foundation. […] According to the Brain Aneurysm Foundation: Most people who have brain aneurysms are ages 35-60, but they can happen in all age groups including children. Most people develop aneurysms after they turn 40. […] For the general population, doctors dont recommend testing. However, if you have more than one relative with an aneurysm, doctors recommend screening every five years starting at age 30, Simon said. […] In many cases, you dont. Often aneurysms dont rupture, grow or cause problems, and doctors opt to keep them under surveillance to make sure they stay that way.

• #58 The Medical Minute: The dangers of cerebral aneurysms | Penn State University

  https://www.psu.edu/news/hershey/story/medical-minute-dangers-cerebral-aneurysms

  For roughly 6.8 million Americans currently living with aneurysms, those blisters occur in the brain, according to the Brain Aneurysm Foundation. […] Most people who have brain aneurysms are ages 35-60, but they can happen in all age groups including children. Most people develop aneurysms after they turn 40. […] Women are more likely than men to have a brain aneurysm. […] Women older than 55 have a higher risk of brain aneurysm rupture than men. […] African-Americans and Hispanics have more brain aneurysms than white people. […] Twenty percent of people with an aneurysm in their brain have more than one. […] For the general population, doctors dont recommend testing. However, if you have more than one relative with an aneurysm, doctors recommend screening every five years starting at age 30, Simon said. […] In many cases, you dont. Often aneurysms dont rupture, grow or cause problems, and doctors opt to keep them under surveillance to make sure they stay that way.

• #59 Guidelines on Management of Patients With Unruptured Intracranial Aneurysms

  https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2015/07/07/15/20/guidelines-for-the-management-of-patients-with-unruptured-intracranial-aneurysms

  Guidelines for the Management of Patients With Unruptured Intracranial Aneurysms: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke 2015;Jun 18:[Epub ahead of print]. […] Given that smoking appears to increase the risk of UIA formation, patients with UIA should be counseled regarding the importance of smoking cessation (Class I; Level of Evidence B). […] Aneurysmal growth may increase the risk of rupture, and intermittent imaging studies to follow those UIAs managed conservatively should be considered (Class I; Level of Evidence B). […] Patients with 2 family members with IA or SAH should be offered aneurysmal screening by CTA or MRA. Risk factors that predict a particularly high risk of aneurysm occurrence in such families include history of hypertension, smoking, and female sex (Class I; Level of Evidence B).

• #60 Brain (Cerebral) Aneurysm Imaging: Practice Essentials, Computed Tomography, Magnetic Resonance Imaging

  https://emedicine.medscape.com/article/337027-overview

  For patients with UIAs that are managed noninvasively without either surgical or endovascular intervention, radiographic follow-up with MRA or CTA at regular intervals is indicated. […] Surveillance imaging after endovascular treatment of UIAs lacking high-risk features for recurrence is probably indicated. […] Patients with 2 family members with IA or SAH should be offered aneurysmal screening by CTA or MRA. Risk factors that predict a particularly high risk of aneurysm occurrence in such families include history of hypertension, smoking, and female sex. […] The American Heart Association/American Stroke Association (AHA/ASA) guidelines for the management of unruptured intracranial aneurysms (UIA) includes the following imaging recommendations.

• #61 Cerebral Aneurysm Follow-Up: How Standards Have Changed and Why – Endovascular Today

  https://evtoday.com/articles/2019-feb/cerebral-aneurysm-follow-up-how-standards-have-changed-and-why

  Based on these findings, follow-up beyond 10 years is warranted. […] The timing and imaging modality used in the follow-up of endovascularly treated cerebral aneurysms will vary based on institutional preference and expertise. […] In general, early follow-up with DSA within the first 3 to 12 months is most common. […] Imaging follow-up beyond 10 years from treatment is recommended for all treated aneurysms based on the potential for delayed recanalization of certain types of high-risk aneurysms and the 1 in 25 likelihood of de novo aneurysm development in the all-comer treated population.

• #62 Cerebral Aneurysm Follow-Up: How Standards Have Changed and Why – Endovascular Today

  https://evtoday.com/articles/2019-feb/cerebral-aneurysm-follow-up-how-standards-have-changed-and-why

  Based on these findings, follow-up beyond 10 years is warranted. […] The timing and imaging modality used in the follow-up of endovascularly treated cerebral aneurysms will vary based on institutional preference and expertise. […] In general, early follow-up with DSA within the first 3 to 12 months is most common. […] Imaging follow-up beyond 10 years from treatment is recommended for all treated aneurysms based on the potential for delayed recanalization of certain types of high-risk aneurysms and the 1 in 25 likelihood of de novo aneurysm development in the all-comer treated population.

• #63 Cerebral Aneurysm Follow-Up: How Standards Have Changed and Why – Endovascular Today

  https://evtoday.com/articles/2019-feb/cerebral-aneurysm-follow-up-how-standards-have-changed-and-why

  Based on these findings, follow-up beyond 10 years is warranted. […] The timing and imaging modality used in the follow-up of endovascularly treated cerebral aneurysms will vary based on institutional preference and expertise. […] In general, early follow-up with DSA within the first 3 to 12 months is most common. […] Imaging follow-up beyond 10 years from treatment is recommended for all treated aneurysms based on the potential for delayed recanalization of certain types of high-risk aneurysms and the 1 in 25 likelihood of de novo aneurysm development in the all-comer treated population.

• #64 Cerebral Aneurysm Follow-Up: How Standards Have Changed and Why – Endovascular Today

  https://evtoday.com/articles/2019-feb/cerebral-aneurysm-follow-up-how-standards-have-changed-and-why

  Based on these findings, follow-up beyond 10 years is warranted. […] The timing and imaging modality used in the follow-up of endovascularly treated cerebral aneurysms will vary based on institutional preference and expertise. […] In general, early follow-up with DSA within the first 3 to 12 months is most common. […] Imaging follow-up beyond 10 years from treatment is recommended for all treated aneurysms based on the potential for delayed recanalization of certain types of high-risk aneurysms and the 1 in 25 likelihood of de novo aneurysm development in the all-comer treated population.

• #65 Cerebral Aneurysm Follow-Up: How Standards Have Changed and Why – Endovascular Today

  https://evtoday.com/articles/2019-feb/cerebral-aneurysm-follow-up-how-standards-have-changed-and-why

  Neurointerventional surgery has become the primary management strategy for both ruptured and unruptured cerebral aneurysms in most institutions. […] However, the long-term angiographic durability of coiling for both ruptured and unruptured aneurysms has been raised as a concern, with reports that one-fifth of patients demonstrate some form of occlusion status deterioration in early imaging follow-up. […] At present, no official guideline outlines the optimal evidence-based approach to follow-up frequency and imaging modality type. […] In general, there is no universally agreed upon timetable for imaging and clinical follow-up of treated aneurysms. […] The majority of recurrences occur within the first year after treatment, necessitating an early posttreatment imaging study. […] Historically, aneurysm follow-up was concluded at 5 years because data examining aneurysm recurrence beyond the 5-year mark were scant.

• #66 Cerebral Aneurysm Follow-Up: How Standards Have Changed and Why – Endovascular Today

  https://evtoday.com/articles/2019-feb/cerebral-aneurysm-follow-up-how-standards-have-changed-and-why

  Based on these findings, follow-up beyond 10 years is warranted. […] The timing and imaging modality used in the follow-up of endovascularly treated cerebral aneurysms will vary based on institutional preference and expertise. […] In general, early follow-up with DSA within the first 3 to 12 months is most common. […] Imaging follow-up beyond 10 years from treatment is recommended for all treated aneurysms based on the potential for delayed recanalization of certain types of high-risk aneurysms and the 1 in 25 likelihood of de novo aneurysm development in the all-comer treated population.

• #67 Brain Aneurysm | Brain Institute | OHSU

  https://www.ohsu.edu/brain-institute/brain-aneurysm

  At the OHSU Brain Institute, we offer the regions most advanced care to diagnose, treat and monitor brain aneurysms. […] A surveillance clinic for skilled monitoring. […] At OHSU, patients with a history of aneurysm are routinely screened at our aneurysm surveillance clinic. Screening may be recommended for people with a strong family history of aneurysm or those with conditions that increase the risk of aneurysm.

• #68 Brain Aneurysm | Brain Institute | OHSU

  https://www.ohsu.edu/brain-institute/brain-aneurysm

  At the OHSU Brain Institute, we offer the regions most advanced care to diagnose, treat and monitor brain aneurysms. […] A surveillance clinic for skilled monitoring. […] At OHSU, patients with a history of aneurysm are routinely screened at our aneurysm surveillance clinic. Screening may be recommended for people with a strong family history of aneurysm or those with conditions that increase the risk of aneurysm.

• #69 Brain Aneurysm Diagnosis and Treatment | Brain Institute | OHSU

  https://www.ohsu.edu/brain-institute/brain-aneurysm-diagnosis-and-treatment

  The OHSU Brain Institute is a national leader in diagnosing and treating brain aneurysms. […] Our aneurysm surveillance clinic gives you: […] Regular monitoring. […] The goal is to prevent a second rupture. […] The goal is to prevent rupture. […] You also might have regular scans to monitor the aneurysm. […] OHSU neurointerventionalists were the first on the West Coast to use a pipeline embolization device, or PED, to treat wide-neck aneurysms.

• #70 Brain Aneurysm Diagnosis and Treatment | Brain Institute | OHSU

  https://www.ohsu.edu/brain-institute/brain-aneurysm-diagnosis-and-treatment

  The OHSU Brain Institute is a national leader in diagnosing and treating brain aneurysms. […] Our aneurysm surveillance clinic gives you: […] Regular monitoring. […] The goal is to prevent a second rupture. […] The goal is to prevent rupture. […] You also might have regular scans to monitor the aneurysm. […] OHSU neurointerventionalists were the first on the West Coast to use a pipeline embolization device, or PED, to treat wide-neck aneurysms.

• #71 Statistics and Facts – Brain Aneurysm Foundation

  https://www.bafound.org/statistics-and-facts/

  Ruptured brain aneurysms are fatal in about 50% of cases. Of those who survive, about 66% suffer some permanent neurological deficit. […] Approximately 15% of people with a ruptured aneurysm die before reaching the hospital. Most of the deaths are due to rapid and massive brain injury from the initial bleeding. […] Accurate early diagnosis of a ruptured brain aneurysm is critical, as the initial hemorrhage may be fatal or result in devastating neurologic outcomes. […] Despite the widespread availability of brain imaging that can detect a ruptured brain aneurysm, misdiagnosis or delays in diagnosis occur in up to one quarter of patients when initially seeking medical attention. In three out of four cases, misdiagnosis results from a failure to do a scan. […] The treatment of ruptured brain aneurysms is far more costly than the treatment of unruptured aneurysms: The cost of a brain aneurysm treated by surgical clipping more than doubles after the aneurysm has ruptured. The cost of a brain aneurysm treated by endovascular coiling increases by about 70% after the aneurysm has ruptured.

• #72 Statistics and Facts – Brain Aneurysm Foundation

  https://www.bafound.org/statistics-and-facts/

  Ruptured brain aneurysms are fatal in about 50% of cases. Of those who survive, about 66% suffer some permanent neurological deficit. […] Approximately 15% of people with a ruptured aneurysm die before reaching the hospital. Most of the deaths are due to rapid and massive brain injury from the initial bleeding. […] Accurate early diagnosis of a ruptured brain aneurysm is critical, as the initial hemorrhage may be fatal or result in devastating neurologic outcomes. […] Despite the widespread availability of brain imaging that can detect a ruptured brain aneurysm, misdiagnosis or delays in diagnosis occur in up to one quarter of patients when initially seeking medical attention. In three out of four cases, misdiagnosis results from a failure to do a scan. […] The treatment of ruptured brain aneurysms is far more costly than the treatment of unruptured aneurysms: The cost of a brain aneurysm treated by surgical clipping more than doubles after the aneurysm has ruptured. The cost of a brain aneurysm treated by endovascular coiling increases by about 70% after the aneurysm has ruptured.

• #73 Should Surveillance of Unruptured Brain Aneurysms Be Selective?logo-32logo-40logo-60NEJM Journal WatchnejmJW_1L_RGB-b

  https://www.jwatch.org/na55077/2022/07/05/should-surveillance-unruptured-brain-aneurysms-be

  Unruptured brain aneurysms are present in about 3% of the general population. […] For small aneurysms, the optimal strategy for surveillance of aneurysm growth is uncertain. […] The authors found that to prevent one case of subarachnoid hemorrhage (SAH), the number needed to screen was as follows: U.S., 2222; U.K., 1910; Netherlands, 2040. […] In general, for the U.S. and U.K., no surveillance was the most cost-effective strategy, but in the Netherlands, annual surveillance until age 70 was considered reasonable. […] For individuals in the U.S. and U.K. at increased risk for aneurysm growth, annual surveillance or imaging in the first and fifth year was cost effective in individuals younger than 60 years.

• #74 Should Surveillance of Unruptured Brain Aneurysms Be Selective?logo-32logo-40logo-60NEJM Journal WatchnejmJW_1L_RGB-b

  https://www.jwatch.org/na55077/2022/07/05/should-surveillance-unruptured-brain-aneurysms-be

  Unruptured brain aneurysms are present in about 3% of the general population. […] For small aneurysms, the optimal strategy for surveillance of aneurysm growth is uncertain. […] The authors found that to prevent one case of subarachnoid hemorrhage (SAH), the number needed to screen was as follows: U.S., 2222; U.K., 1910; Netherlands, 2040. […] In general, for the U.S. and U.K., no surveillance was the most cost-effective strategy, but in the Netherlands, annual surveillance until age 70 was considered reasonable. […] For individuals in the U.S. and U.K. at increased risk for aneurysm growth, annual surveillance or imaging in the first and fifth year was cost effective in individuals younger than 60 years.

• #75 Cerebral Aneurysm: Early Detection & Proactive Care

  https://www.illuminate.ai/disease-pages/cerebral-aneurysm

  In the U.S., over 30,000 brain aneurysms rupture annually, with 50% being fatal and 25% causing serious health issues. Timely follow-up and intervention are crucial in reducing these dire outcomes. […] An estimated 6.7 million people in the United States have an unruptured brain aneurysm, equating to about 1 in 50 people. Each year, approximately 30,000 people in the U.S. suffer a brain aneurysm rupture, which translates to a rupture every 18 minutes. […] Identifies the entire cerebral aneurysm population for improved planning and care. Removes the burden of surveillance from the neurosurgeon. […] Ensures radiologists actionable incidental findings are acted upon. Removes the follow-up responsibility from radiology. […] Improves health equity and patient outcomes. Minimizes medical legal risk.

• #76 Brain (Cerebral) Aneurysm Imaging: Practice Essentials, Computed Tomography, Magnetic Resonance Imaging

  https://emedicine.medscape.com/article/337027-overview

  Cerebral aneurysm is a cerebrovascular disorder in which weakness in the wall of an intracranial artery causes a localized dilation or ballooning of the blood vessel. If an aneurysm ruptures, blood leaks into the space around the brain and causes a subarachnoid hemorrhage (SAH). Unruptured intracranial aneurysms (UIAs) are relatively common in the general population, found in and estimated 1-5% of the general population. […] They are being discovered incidentally with increasing frequency because of the widespread use of high-resolution magnetic resonance imaging (MRI) scanning. Only a very small percentage (1 in 200 to 400) will rupture. […] After the diagnosis, the specific anatomic details of the aneurysm must be reported to categorize the lesion, select appropriate management, and assess treatment outcomes.

• #77 Unruptured Intracranial Aneurysm: Screening, Prevalence and Risk Factors

  https://neurointervention.org/journal/view.php?number=348

  In studies analyzing data from a cohort of 1 million people from the Korean NHIS, the crude incidence of UIA increased steadily from 29.6 per 100,000 person-years in 2008, to 90.0 per 100,000 person-years in 2016. […] It is believed that this is due to an increase in the number of asymptomatic cerebral aneurysms discovered through screening rather than an increase in the number of development of cerebral aneurysms. […] Meanwhile, the incidence of ruptured intracranial aneurysm has decreased, which may be due to an increase in the treatment of UIA and improved management of hypertension through health screening. […] The worldwide incidence of SAH also declined between 1980 and 2010 in Europe, Asia and North America, in parallel with a global decline in prevalence of hypertension and smoking, which is also in good contrast with an increasing rate of diagnosis of UIA. […] Therefore, the regional or ethnic difference should also be considered for elucidating the effective relationship between the active screening and treatment of UIA, and their preventive effect for SAH.

• #78 Unruptured Intracranial Aneurysm: Screening, Prevalence and Risk Factors

  https://neurointervention.org/journal/view.php?number=348

  In studies analyzing data from a cohort of 1 million people from the Korean NHIS, the crude incidence of UIA increased steadily from 29.6 per 100,000 person-years in 2008, to 90.0 per 100,000 person-years in 2016. […] It is believed that this is due to an increase in the number of asymptomatic cerebral aneurysms discovered through screening rather than an increase in the number of development of cerebral aneurysms. […] Meanwhile, the incidence of ruptured intracranial aneurysm has decreased, which may be due to an increase in the treatment of UIA and improved management of hypertension through health screening. […] The worldwide incidence of SAH also declined between 1980 and 2010 in Europe, Asia and North America, in parallel with a global decline in prevalence of hypertension and smoking, which is also in good contrast with an increasing rate of diagnosis of UIA. […] Therefore, the regional or ethnic difference should also be considered for elucidating the effective relationship between the active screening and treatment of UIA, and their preventive effect for SAH.

• #79 Unruptured Intracranial Aneurysm: Screening, Prevalence and Risk Factors

  https://neurointervention.org/journal/view.php?number=348

  In studies analyzing data from a cohort of 1 million people from the Korean NHIS, the crude incidence of UIA increased steadily from 29.6 per 100,000 person-years in 2008, to 90.0 per 100,000 person-years in 2016. […] It is believed that this is due to an increase in the number of asymptomatic cerebral aneurysms discovered through screening rather than an increase in the number of development of cerebral aneurysms. […] Meanwhile, the incidence of ruptured intracranial aneurysm has decreased, which may be due to an increase in the treatment of UIA and improved management of hypertension through health screening. […] The worldwide incidence of SAH also declined between 1980 and 2010 in Europe, Asia and North America, in parallel with a global decline in prevalence of hypertension and smoking, which is also in good contrast with an increasing rate of diagnosis of UIA. […] Therefore, the regional or ethnic difference should also be considered for elucidating the effective relationship between the active screening and treatment of UIA, and their preventive effect for SAH.

• #80 Illuminate Announces Partnership with Wellstar to Improve Cerebral Aneurysm Surveillance

  https://www.prnewswire.com/news-releases/illuminate-announces-partnership-with-wellstar-to-improve-cerebral-aneurysm-surveillance-302178505.html

  Expands existing Illuminate aneurysm surveillance capability to include management of incidentally found cerebral aneurysms. […] This collaboration aims to outline the entire clinical surveillance decision process for incidentally found cerebral aneurysms and identify new and appropriate clinical parameters for treating these patients. […] These new capabilities will help save lives and reduce delays in care by facilitating the development of cerebral aneurysm surveillance programs. […] „This partnership will provide valuable clinical insights that will further enhance cerebral aneurysm treatment and the patient experience,” notes Dr. William Humphries, Neurosurgeon, Wellstar, „Given the complexities, fragile nature, and the fact that cerebral aneurysms are often found incidentally, we believe this technology provides a significant opportunity to address a gap in neurovascular care and better optimize treatment plans.” […] We believe the unique capability of our AI will enable the improved management of patients with incidentally found Cerebral Aneurysms, enabling providers to be more proactive and provide more treatment options for their patients.

• #81 Study for familial brain aneurysm recognition | Baptist Health | Jacksonville FL

  https://www.wolfsonchildrens.com/about/news/news-release/baptist-health-launches-study-for-familial-brain-aneurysm-recognition-as-part-of-brain-aneurysm-awareness-month

  Baptist Health of Northeast Florida has launched a research study funded by The State of Florida to assess the hereditary probability of brain aneurysms in families. The findings will then be used to advance the use of screening during routine medical exams, and finding lower-cost screening options for patients who may be at risk. […] „With this study, we aim to understand better the epidemiology of familial aneurysms and, at the same time, understand the genetic markers for intracranial aneurysms that may provide new targets for future screening processes and therapies and potentially help us save lives.” […] „Raising awareness of the signs and symptoms of brain aneurysms is important and improves our ability to help patients before aneurysms can cause a problem. Now, with this study, we are taking further action to advance the care and treatment we offer our patients.”

• #82

  https://journals.lww.com/neurosurgpraconline/fulltext/2020/12000/intracranial_aneurysms__does_size_really_matter_.5.aspx

  The ruptured aneurysms were mostly smaller than reported previously. Surgical clipping was at equipoise with endovascular treatments. Further studies to correlate aneurysmal characteristics to the risk of rupture are needed. […] In both crude and adjusted models, there was insufficient evidence to conclude that there was an association between aneurysm size and the odds of rupture. […] Logistic regression analysis failed to find an effect of increasing size on the risk of rupture of IAs. […] The retrospective arm of ISUIA suggested that aneurysms 10mm should be managed conservatively because they have a very low (0.05% per year) propensity to rupture. […] Given such severe outcomes after SAH, there is a pressing need to make uniform guidelines that can be used to better stratify the risk of rupture and manage these patients. […] The data suggest that size cannot be the sole determinant in selecting appropriate therapy for incidental aneurysms.

• #83 Time-of-Flight MRA of Intracranial Aneurysms with Interval Surveillance, Clinical Segmentation and Annotations | Scientific Data

  https://www.nature.com/articles/s41597-024-03397-8

  Intracranial aneurysms (IAs) are present in 26% of the global population and can be catastrophic upon rupture with a mortality rate of 3050%. IAs are commonly detected through time-of-flight magnetic resonance angiography (TOF-MRA), however, this data is rarely available for research and training purposes. […] This dataset is the first to provide interval surveillance imaging for supporting the understanding of IA growth and stability. […] The AneurRisk Project thus arose in 2008 to unite researchers in the goal to uncover the complex pathology around aneurysms, providing DSA scans of 65 patients with IAs. […] To further support this effort to address bottlenecks in data availability, we provide an open-access annotated TOF-MRA dataset comprising 63 subjects containing IAs. Importantly, this work differs to the existing databases by providing interval surveillance imaging on 24 subjects, ranging from 112 years of surveillance. This data is useful for investigating changes in size and morphology of IAs over time, which may help validate the predictive risk of IA geometry and fluid dynamics in rupture.

• #84 Time-of-Flight MRA of Intracranial Aneurysms with Interval Surveillance, Clinical Segmentation and Annotations | Scientific Data

  https://www.nature.com/articles/s41597-024-03397-8

  Intracranial aneurysms (IAs) are present in 26% of the global population and can be catastrophic upon rupture with a mortality rate of 3050%. IAs are commonly detected through time-of-flight magnetic resonance angiography (TOF-MRA), however, this data is rarely available for research and training purposes. […] This dataset is the first to provide interval surveillance imaging for supporting the understanding of IA growth and stability. […] The AneurRisk Project thus arose in 2008 to unite researchers in the goal to uncover the complex pathology around aneurysms, providing DSA scans of 65 patients with IAs. […] To further support this effort to address bottlenecks in data availability, we provide an open-access annotated TOF-MRA dataset comprising 63 subjects containing IAs. Importantly, this work differs to the existing databases by providing interval surveillance imaging on 24 subjects, ranging from 112 years of surveillance. This data is useful for investigating changes in size and morphology of IAs over time, which may help validate the predictive risk of IA geometry and fluid dynamics in rupture.

• #85 Time-of-Flight MRA of Intracranial Aneurysms with Interval Surveillance, Clinical Segmentation and Annotations | Scientific Data

  https://www.nature.com/articles/s41597-024-03397-8

  Patients having undergone interval surveillance imaging have been further analysed for increases in size, daughter sac formation, aneurysm recurrence, new aneurysm formation, and treatment. […] This dataset aims to support the effort to reduce bottlenecks in data availability which currently limits research and modelling into IA growth and rupture dynamics.

• #86 Illuminate Announces Partnership with Wellstar to Improve Cerebral Aneurysm Surveillance

  https://www.prnewswire.com/news-releases/illuminate-announces-partnership-with-wellstar-to-improve-cerebral-aneurysm-surveillance-302178505.html

  Expands existing Illuminate aneurysm surveillance capability to include management of incidentally found cerebral aneurysms. […] This collaboration aims to outline the entire clinical surveillance decision process for incidentally found cerebral aneurysms and identify new and appropriate clinical parameters for treating these patients. […] These new capabilities will help save lives and reduce delays in care by facilitating the development of cerebral aneurysm surveillance programs. […] „This partnership will provide valuable clinical insights that will further enhance cerebral aneurysm treatment and the patient experience,” notes Dr. William Humphries, Neurosurgeon, Wellstar, „Given the complexities, fragile nature, and the fact that cerebral aneurysms are often found incidentally, we believe this technology provides a significant opportunity to address a gap in neurovascular care and better optimize treatment plans.” […] We believe the unique capability of our AI will enable the improved management of patients with incidentally found Cerebral Aneurysms, enabling providers to be more proactive and provide more treatment options for their patients.

• #87 Study Reveals Insomnia Could Be a Risk Factor for Brain Aneurysms

  https://www.uspharmacist.com/article/study-reveals-insomnia-could-be-a-risk-factor-for-brain-aneurysms

  According to the analysis, a genetic predisposition for insomnia was associated with a 24% increased risk for intracranial aneurysm and aneurysmal subarachnoid hemorrhage. […] The researchers concluded that this Mendelian randomization study suggests that smoking, insomnia, and high blood pressure are major risk factors for intracranial aneurysm and aneurysmal subarachnoid hemorrhage. […] The association between insomnia and intracranial aneurysm has not been reported previously, and these findings warrant confirmation in future studies. Our research supports the thinking that risk factors that people can change or manage may impact brain aneurysms and hemorrhage risk.

• #88 Insomnia may be a risk factor for highly fatal brain aneurysm rupture | American Heart Association

  https://newsroom.heart.org/news/insomnia-may-be-a-risk-factor-for-highly-fatal-brain-aneurysm-rupture

  Researchers identified insomnia as a potential risk factor for brain aneurysm, also called an intracranial aneurysm, and a type of stroke called an aneurysmal subarachnoid hemorrhage. […] According to researchers, the finding that insomnia may be a potential risk factor for intracranial aneurysm is new and calls for additional research. […] Ruptured aneurysms are highly fatal. It is, therefore, extremely important to identify modifiable risk factors that can help prevent aneurysms from rupturing, said study author Susanna C. Larsson, Ph.D., associate professor in the unit of cardiovascular and nutritional epidemiology at the Karolinska Institutet in Stockholm, Sweden, and the unit of medical epidemiology at Uppsala University in Uppsala, Sweden. […] The association between insomnia and intracranial aneurysm has not been reported previously, and these findings warrant confirmation in future studies, Larsson said. Our research supports the thinking that risk factors that people can change or manage may impact brain aneurysms and hemorrhage risk. Once confirmed, future studies should examine ways to incorporate this knowledge into prevention programs and therapies.

• #89 Exploring Aneurysm Risk Factors in Different Age Groups – CVRTI

  https://cvrti.utah.edu/exploring-aneurysm-risk-factors-in-different-age-groups/

  A small aneurysm with very few symptoms might need nothing more than monitoring and regular imaging studies to assess its growth. […] For those with symptomatic or larger aneurysms, intervention may need to happen sooner and go beyond imaging tests. […] Awareness of the demographics and risk factors associated with aneurysms in various age groups is important for proper treatment and prevention. […] Individualized management and follow-up strategies based on demographics can improve outcomes for those at risk or impacted by the condition.

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